Kim Orth - Publications

Affiliations: 
University of Texas Southwestern, Dallas, TX, United States 

41/99 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Peng W, Casey AK, Fernandez J, Carpinone EM, Servage KA, Chen Z, Li Y, Tomchick DR, Starai VJ, Orth K. A distinct inhibitory mechanism of the V-ATPase by Vibrio VopQ revealed by cryo-EM. Nature Structural & Molecular Biology. PMID 32424347 DOI: 10.1038/s41594-020-0429-1  0.4
2018 Sreelatha A, Yee SS, Lopez VA, Park BC, Kinch LN, Pilch S, Servage KA, Zhang J, Jiou J, Karasiewicz-Urbańska M, Łobocka M, Grishin NV, Orth K, Kucharczyk R, Pawłowski K, et al. Protein AMPylation by an Evolutionarily Conserved Pseudokinase. Cell. PMID 30270044 DOI: 10.1016/j.cell.2018.08.046  0.4
2015 Salomon D, Klimko JA, Trudgian DC, Kinch LN, Grishin NV, Mirzaei H, Orth K. Type VI Secretion System Toxins Horizontally Shared between Marine Bacteria. Plos Pathogens. 11: e1005128. PMID 26305100 DOI: 10.1371/journal.ppat.1005128  0.4
2015 Sreelatha A, Bennett TL, Carpinone EM, O'Brien KM, Jordan KD, Burdette DL, Orth K, Starai VJ. Vibrio effector protein VopQ inhibits fusion of V-ATPase-containing membranes. Proceedings of the National Academy of Sciences of the United States of America. 112: 100-5. PMID 25453092 DOI: 10.1073/pnas.1413764111  0.4
2014 Ham H, Woolery AR, Tracy C, Stenesen D, Krämer H, Orth K. Unfolded protein response-regulated Drosophila Fic (dFic) protein reversibly AMPylates BiP chaperone during endoplasmic reticulum homeostasis. The Journal of Biological Chemistry. 289: 36059-69. PMID 25395623 DOI: 10.1074/jbc.M114.612515  0.4
2014 Calder T, de Souza Santos M, Attah V, Klimko J, Fernandez J, Salomon D, Krachler AM, Orth K. Structural and regulatory mutations in Vibrio parahaemolyticus type III secretion systems display variable effects on virulence. Fems Microbiology Letters. 361: 107-14. PMID 25288215 DOI: 10.1111/1574-6968.12619  0.4
2014 Calder T, Kinch LN, Fernandez J, Salomon D, Grishin NV, Orth K. Vibrio type III effector VPA1380 is related to the cysteine protease domain of large bacterial toxins. Plos One. 9: e104387. PMID 25099122 DOI: 10.1371/journal.pone.0104387  0.4
2014 Yu X, Woolery AR, Luong P, Hao YH, Grammel M, Westcott N, Park J, Wang J, Bian X, Demirkan G, Hang HC, Orth K, LaBaer J. Copper-catalyzed azide-alkyne cycloaddition (click chemistry)-based detection of global pathogen-host AMPylation on self-assembled human protein microarrays. Molecular & Cellular Proteomics : McP. 13: 3164-76. PMID 25073739 DOI: 10.1074/mcp.M114.041103  0.4
2014 Salomon D, Kinch LN, Trudgian DC, Guo X, Klimko JA, Grishin NV, Mirzaei H, Orth K. Marker for type VI secretion system effectors. Proceedings of the National Academy of Sciences of the United States of America. 111: 9271-6. PMID 24927539 DOI: 10.1073/pnas.1406110111  0.4
2014 Lewallen DM, Sreelatha A, Dharmarajan V, Madoux F, Chase P, Griffin PR, Orth K, Hodder P, Thompson PR. Inhibiting AMPylation: a novel screen to identify the first small molecule inhibitors of protein AMPylation. Acs Chemical Biology. 9: 433-42. PMID 24274060 DOI: 10.1021/cb4006886  0.4
2013 Salomon D, Guo Y, Kinch LN, Grishin NV, Gardner KH, Orth K. Effectors of animal and plant pathogens use a common domain to bind host phosphoinositides. Nature Communications. 4: 2973. PMID 24346350 DOI: 10.1038/ncomms3973  0.4
2013 Hawley CA, Watson CA, Orth K, Krachler AM. A MAM7 peptide-based inhibitor of Staphylococcus aureus adhesion does not interfere with in vitro host cell function. Plos One. 8: e81216. PMID 24265842 DOI: 10.1371/journal.pone.0081216  0.4
2013 Sreelatha A, Orth K, Starai VJ. The pore-forming bacterial effector, VopQ, halts autophagic turnover. Autophagy. 9: 2169-70. PMID 24145145 DOI: 10.4161/auto.26449  0.4
2013 Altura MA, Heath-Heckman EA, Gillette A, Kremer N, Krachler AM, Brennan C, Ruby EG, Orth K, McFall-Ngai MJ. The first engagement of partners in the Euprymna scolopes-Vibrio fischeri symbiosis is a two-step process initiated by a few environmental symbiont cells. Environmental Microbiology. 15: 2937-50. PMID 23819708 DOI: 10.1111/1462-2920.12179  0.4
2013 Krachler AM, Orth K. Targeting the bacteria-host interface: strategies in anti-adhesion therapy. Virulence. 4: 284-94. PMID 23799663 DOI: 10.4161/viru.24606  0.4
2013 Sreelatha A, Bennett TL, Zheng H, Jiang QX, Orth K, Starai VJ. Vibrio effector protein, VopQ, forms a lysosomal gated channel that disrupts host ion homeostasis and autophagic flux. Proceedings of the National Academy of Sciences of the United States of America. 110: 11559-64. PMID 23798441 DOI: 10.1073/pnas.1307032110  0.4
2012 Ham H, Orth K. The role of type III secretion System 2 in Vibrio parahaemolyticus pathogenicity Journal of Microbiology. 50: 719-725. PMID 23124738 DOI: 10.1007/s12275-012-2550-2  0.4
2012 Zhang L, Krachler AM, Broberg CA, Li Y, Mirzaei H, Gilpin CJ, Orth K. Type III effector VopC mediates invasion for Vibrio species. Cell Reports. 1: 453-60. PMID 22787576 DOI: 10.1016/j.celrep.2012.04.004  0.4
2012 Krachler AM, Mende K, Murray C, Orth K. In vitro characterization of multivalent adhesion molecule 7-based inhibition of multidrug-resistant bacteria isolated from wounded military personnel. Virulence. 3: 389-99. PMID 22722243 DOI: 10.4161/viru.20816  0.4
2012 Krachler AM, Ham H, Orth K. Turnabout is fair play: use of the bacterial Multivalent Adhesion Molecule 7 as an antimicrobial agent. Virulence. 3: 68-71. PMID 22086133 DOI: 10.4161/viru.3.1.18172  0.4
2011 Krachler AM, Woolery AR, Orth K. Manipulation of kinase signaling by bacterial pathogens. The Journal of Cell Biology. 195: 1083-92. PMID 22123833 DOI: 10.1083/jcb.201107132  0.4
2011 Ham H, Orth K. De-AMPylation unmasked: Modulation of host membrane trafficking Science Signaling. 4. PMID 21990428 DOI: 10.1126/scisignal.2002458  0.4
2011 Krachler AM, Orth K. Functional characterization of the interaction between bacterial adhesin multivalent adhesion molecule 7 (MAM7) protein and its host cell ligands. The Journal of Biological Chemistry. 286: 38939-47. PMID 21937438 DOI: 10.1074/jbc.M111.291377  0.4
2011 Ham H, Sreelatha A, Orth K. Manipulation of host membranes by bacterial effectors Nature Reviews Microbiology. 9: 635-646. PMID 21765451 DOI: 10.1038/nrmicro2602  0.4
2011 Krachler AM, Ham H, Orth K. Outer membrane adhesion factor multivalent adhesion molecule 7 initiates host cell binding during infection by gram-negative pathogens. Proceedings of the National Academy of Sciences of the United States of America. 108: 11614-9. PMID 21709226 DOI: 10.1073/pnas.1102360108  0.4
2011 Li Y, Al-Eryani R, Yarbrough ML, Orth K, Ball HL. Characterization of AMPylation on threonine, serine, and tyrosine using mass spectrometry. Journal of the American Society For Mass Spectrometry. 22: 752-61. PMID 21472612 DOI: 10.1007/s13361-011-0084-1  0.4
2011 Hao YH, Chuang T, Ball HL, Luong P, Li Y, Flores-Saaib RD, Orth K. Characterization of a rabbit polyclonal antibody against threonine-AMPylation. Journal of Biotechnology. 151: 251-4. PMID 21185336 DOI: 10.1016/j.jbiotec.2010.12.013  0.4
2010 Luong P, Kinch LN, Brautigam CA, Grishin NV, Tomchick DR, Orth K. Kinetic and structural insights into the mechanism of AMPylation by VopS Fic domain. The Journal of Biological Chemistry. 285: 20155-63. PMID 20410310 DOI: 10.1074/jbc.M110.114884  0.4
2009 Burdette DL, Seemann J, Orth K. Vibrio VopQ induces PI3-kinase-independent autophagy and antagonizes phagocytosis. Molecular Microbiology. 73: 639-49. PMID 19627496 DOI: 10.1111/j.1365-2958.2009.06798.x  0.4
2009 Kinch LN, Yarbrough ML, Orth K, Grishin NV. Fido, a novel AMPylation domain common to fic, doc, and AvrB. Plos One. 4: e5818. PMID 19503829 DOI: 10.1371/journal.pone.0005818  0.4
2009 Yarbrough ML, Orth K. AMPylation is a new post-translational modiFICation. Nature Chemical Biology. 5: 378-9. PMID 19448605 DOI: 10.1038/nchembio0609-378  0.36
2009 Yarbrough ML, Li Y, Kinch LN, Grishin NV, Ball HL, Orth K. AMPylation of Rho GTPases by Vibrio VopS disrupts effector binding and downstream signaling. Science (New York, N.Y.). 323: 269-72. PMID 19039103 DOI: 10.1126/science.1166382  0.4
2009 Burdette DL, Yarbrough ML, Orth K. Not without cause: Vibrio parahaemolyticus induces acute autophagy and cell death. Autophagy. 5: 100-2. PMID 19011375  0.4
2008 Burdette DL, Yarbrough ML, Orvedahl A, Gilpin CJ, Orth K. Vibrio parahaemolyticus orchestrates a multifaceted host cell infection by induction of autophagy, cell rounding, and then cell lysis. Proceedings of the National Academy of Sciences of the United States of America. 105: 12497-502. PMID 18713860 DOI: 10.1073/pnas.0802773105  0.4
2008 Trosky JE, Liverman AD, Orth K. Yersinia outer proteins: Yops. Cellular Microbiology. 10: 557-65. PMID 18081726 DOI: 10.1111/j.1462-5822.2007.01109.x  0.36
2007 Liverman ADB, Cheng HC, Trosky JE, Leung DW, Yarbrough ML, Burdette DL, Rosen MK, Orth K. Arp2/3-independent assembly of actin by Vibrio type III effector VopL Proceedings of the National Academy of Sciences of the United States of America. 104: 17117-17122. PMID 17942696 DOI: 10.1073/pnas.0703196104  0.4
2007 Trosky JE, Li Y, Mukherjee S, Keitany G, Ball H, Orth K. VopA inhibits ATP binding by acetylating the catalytic loop of MAPK kinases. The Journal of Biological Chemistry. 282: 34299-305. PMID 17881352 DOI: 10.1074/jbc.M706970200  0.36
2006 Mukherjee S, Keitany G, Li Y, Wang Y, Ball HL, Goldsmith EJ, Orth K. Yersinia YopJ acetylates and inhibits kinase activation by blocking phosphorylation. Science (New York, N.Y.). 312: 1211-4. PMID 16728640 DOI: 10.1126/science.1126867  0.4
2004 Trosky JE, Mukherjee S, Burdette DL, Roberts M, McCarter L, Siegel RM, Orth K. Inhibition of MAPK signaling pathways by VopA from Vibrio parahaemolyticus. The Journal of Biological Chemistry. 279: 51953-7. PMID 15459200 DOI: 10.1074/jbc.M407001200  0.4
2003 Hotson A, Chosed R, Shu H, Orth K, Mudgett MB. Xanthomonas type III effector XopD targets SUMO-conjugated proteins in planta. Molecular Microbiology. 50: 377-89. PMID 14617166 DOI: 10.1046/j.1365-2958.2003.03730.x  0.4
2002 Collier-Hyams LS, Zeng H, Sun J, Tomlinson AD, Bao ZQ, Chen H, Madara JL, Orth K, Neish AS. Cutting edge: Salmonella AvrA effector inhibits the key proinflammatory, anti-apoptotic NF-kappa B pathway. Journal of Immunology (Baltimore, Md. : 1950). 169: 2846-50. PMID 12218096 DOI: 10.4049/jimmunol.169.6.2846  0.4
Low-probability matches
2012 Rahman M, Ham H, Liu X, Sugiura Y, Orth K, Krämer H. Visual neurotransmission in Drosophila requires expression of Fic in glial capitate projections. Nature Neuroscience. 15: 871-5. PMID 22544313 DOI: 10.1038/nn.3102  0.24
2012 Alto NM, Orth K. Subversion of cell signaling by pathogens. Cold Spring Harbor Perspectives in Biology. 4: a006114. PMID 22952390 DOI: 10.1101/cshperspect.a006114  0.2
2017 Ray A, Schwartz N, de Souza Santos M, Zhang J, Orth K, Salomon D. Type VI secretion system MIX-effectors carry both antibacterial and anti-eukaryotic activities. Embo Reports. PMID 28912123 DOI: 10.15252/embr.201744226  0.16
2017 de Souza Santos M, Salomon D, Orth K. T3SS effector VopL inhibits the host ROS response, promoting the intracellular survival of Vibrio parahaemolyticus. Plos Pathogens. 13: e1006438. PMID 28640881 DOI: 10.1371/journal.ppat.1006438  0.16
2017 Li P, Kinch LN, Ray A, Dalia AB, Cong Q, Nunan LM, Camilli A, Grishin NV, Salomon D, Orth K. Acute Hepatopancreatic Necrosis Disease (AHPND)-causing Vibrio parahaemolyticus strains maintain an antibacterial Type VI Secretion System with versatile effector repertoires. Applied and Environmental Microbiology. PMID 28432099 DOI: 10.1128/AEM.00737-17  0.16
2016 Ray A, Kinch LN, de Souza Santos M, Grishin NV, Orth K, Salomon D. Proteomics Analysis Reveals Previously Uncharacterized Virulence Factors in Vibrio proteolyticus. Mbio. 7. PMID 27460800 DOI: 10.1128/mBio.01077-16  0.16
2016 Li P, Rivera-Cancel G, Kinch LN, Salomon D, Tomchick DR, Grishin NV, Orth K. Bile salt receptor complex activates a pathogenic type III secretion system. Elife. 5. PMID 27377244 DOI: 10.7554/eLife.15718  0.16
2015 Salomon D, Orth K. Type VI secretion system. Current Biology : Cb. 25: R265-6. PMID 25829005 DOI: 10.1016/j.cub.2015.02.031  0.16
2014 Salomon D, Klimko JA, Orth K. H-NS regulates the Vibrio parahaemolyticus type VI secretion system 1. Microbiology (Reading, England). 160: 1867-73. PMID 24987102 DOI: 10.1099/mic.0.080028-0  0.16
2013 Salomon D, Orth K. What pathogens have taught us about posttranslational modifications. Cell Host & Microbe. 14: 269-79. PMID 24034613 DOI: 10.1016/j.chom.2013.07.008  0.16
2013 Salomon D, Gonzalez H, Updegraff BL, Orth K. Vibrio parahaemolyticus type VI secretion system 1 is activated in marine conditions to target bacteria, and is differentially regulated from system 2. Plos One. 8: e61086. PMID 23613791 DOI: 10.1371/journal.pone.0061086  0.16
2013 Salomon D, Orth K. Lost after translation: post-translational modifications by bacterial type III effectors. Current Opinion in Microbiology. 16: 213-20. PMID 23466212 DOI: 10.1016/j.mib.2013.01.013  0.16
2009 Nejmeddine M, Negi VS, Mukherjee S, Tanaka Y, Orth K, Taylor GP, Bangham CR. HTLV-1-Tax and ICAM-1 act on T-cell signal pathways to polarize the microtubule-organizing center at the virological synapse. Blood. 114: 1016-25. PMID 19494354 DOI: 10.1182/blood-2008-03-136770  0.16
2008 Mukherjee S, Orth K. Microbiology. A protein pupylation paradigm. Science (New York, N.Y.). 322: 1062-3. PMID 19008436 DOI: 10.1126/science.1166485  0.16
2008 Mukherjee S, Orth K. In vitro signaling by MAPK and NFkappaB pathways inhibited by Yersinia YopJ. Methods in Enzymology. 438: 343-53. PMID 18413260 DOI: 10.1016/S0076-6879(07)38024-5  0.16
2008 Le Negrate G, Faustin B, Welsh K, Loeffler M, Krajewska M, Hasegawa P, Mukherjee S, Orth K, Krajewski S, Godzik A, Guiney DG, Reed JC. Salmonella secreted factor L deubiquitinase of Salmonella typhimurium inhibits NF-kappaB, suppresses IkappaBalpha ubiquitination and modulates innate immune responses. Journal of Immunology (Baltimore, Md. : 1950). 180: 5045-56. PMID 18354230  0.16
2008 Mukherjee S, Negi VS, Keitany G, Tanaka Y, Orth K. In vitro activation of the IkappaB kinase complex by human T-cell leukemia virus type-1 Tax. The Journal of Biological Chemistry. 283: 15127-33. PMID 18223255 DOI: 10.1074/jbc.M704831200  0.16
2008 Hao YH, Wang Y, Burdette D, Mukherjee S, Keitany G, Goldsmith E, Orth K. Structural requirements for Yersinia YopJ inhibition of MAP kinase pathways. Plos One. 3: e1375. PMID 18167536 DOI: 10.1371/journal.pone.0001375  0.16
2007 Mukherjee S, Hao YH, Orth K. A newly discovered post-translational modification--the acetylation of serine and threonine residues. Trends in Biochemical Sciences. 32: 210-6. PMID 17412595 DOI: 10.1016/j.tibs.2007.03.007  0.16
2007 Chosed R, Tomchick DR, Brautigam CA, Mukherjee S, Negi VS, Machius M, Orth K. Structural analysis of Xanthomonas XopD provides insights into substrate specificity of ubiquitin-like protein proteases. The Journal of Biological Chemistry. 282: 6773-82. PMID 17204475 DOI: 10.1074/jbc.M608730200  0.16
2006 Chosed R, Mukherjee S, Lois LM, Orth K. Evolution of a signalling system that incorporates both redundancy and diversity: Arabidopsis SUMOylation. The Biochemical Journal. 398: 521-9. PMID 16740136 DOI: 10.1042/BJ20060426  0.16
2019 Peng W, de Souza Santos M, Li Y, Tomchick DR, Orth K. High-resolution cryo-EM structures of the E. coli hemolysin ClyA oligomers. Plos One. 14: e0213423. PMID 31048915 DOI: 10.1371/journal.pone.0213423  0.08
2016 Huebinger RM, Stones DH, de Souza Santos M, Carlson DL, Song J, Vaz DP, Keen E, Wolf SE, Orth K, Krachler AM. Targeting bacterial adherence inhibits multidrug-resistant Pseudomonas aeruginosa infection following burn injury. Scientific Reports. 6: 39341. PMID 27996032 DOI: 10.1038/srep39341  0.08
2013 Zhang L, Orth K. Virulence determinants for Vibrio parahaemolyticus infection. Current Opinion in Microbiology. 16: 70-7. PMID 23433802 DOI: 10.1016/j.mib.2013.02.002  0.08
2011 Broberg CA, Calder TJ, Orth K. Vibrio parahaemolyticus cell biology and pathogenicity determinants. Microbes and Infection. 13: 992-1001. PMID 21782964 DOI: 10.1016/j.micinf.2011.06.013  0.08
2010 Woolery AR, Luong P, Broberg CA, Orth K. AMPylation: Something Old is New Again. Frontiers in Microbiology. 1: 113. PMID 21607083 DOI: 10.3389/fmicb.2010.00113  0.08
2010 Broberg CA, Zhang L, Gonzalez H, Laskowski-Arce MA, Orth K. A Vibrio effector protein is an inositol phosphatase and disrupts host cell membrane integrity. Science (New York, N.Y.). 329: 1660-2. PMID 20724587 DOI: 10.1126/science.1192850  0.08
2010 Broberg CA, Orth K. Tipping the balance by manipulating post-translational modifications. Current Opinion in Microbiology. 13: 34-40. PMID 20071215 DOI: 10.1016/j.mib.2009.12.004  0.08
2018 Fernandez J, Orth K. Rise of a Cereal Killer: The Biology of Magnaporthe oryzae Biotrophic Growth. Trends in Microbiology. PMID 29395728 DOI: 10.1016/j.tim.2017.12.007  0.04
2017 De Nisco NJ, Kanchwala M, Li P, Fernandez J, Xing C, Orth K. The cytotoxic type 3 secretion system 1 of Vibrio rewires host gene expression to subvert cell death and activate cell survival pathways. Science Signaling. 10. PMID 28512145 DOI: 10.1126/scisignal.aal4501  0.04
2011 Grammel M, Luong P, Orth K, Hang HC. A chemical reporter for protein AMPylation. Journal of the American Chemical Society. 133: 17103-5. PMID 21942216 DOI: 10.1021/ja205137d  0.04
2020 Chimalapati S, de Souza Santos M, Lafrance AE, Ray A, Lee WR, Rivera-Cancel G, Vale G, Pawlowski K, Mitsche MA, McDonald JG, Liou J, Orth K. Vibrio deploys type 2 secreted lipase to esterify cholesterol with host fatty acids and mediate cell egress. Elife. 9. PMID 32808593 DOI: 10.7554/eLife.58057  0.01
2020 Servage KA, Stefanius K, Gray HF, Orth K. Proteomic Profiling of Small Extracellular Vesicles Secreted by Human Pancreatic Cancer Cells Implicated in Cellular Transformation. Scientific Reports. 10: 7713. PMID 32382024 DOI: 10.1038/s41598-020-64718-6  0.01
2020 D'Souza RS, Lim JY, Turgut A, Servage K, Zhang J, Orth K, Sosale N, Lazzara M, Allegood J, Casanova JE. Calcium-stimulated disassembly of focal adhesions mediated by an ORP3/IQSec1 complex. Elife. 9. PMID 32234213 DOI: 10.7554/eLife.54113  0.01
2019 Yang H, de Souza Santos M, Lee J, Law HT, Chimalapati S, Verdu EF, Orth K, Vallance BA. A Novel Mouse Model of Enteric Vibrio parahaemolyticus Infection Reveals that the Type III Secretion System 2 Effector VopC Plays a Key Role in Tissue Invasion and Gastroenteritis. Mbio. 10. PMID 31848276 DOI: 10.1128/mBio.02608-19  0.01
2019 Bhargava V, Goldstein CD, Russell L, Xu L, Ahmed M, Li W, Casey A, Servage K, Kollipara R, Picciarelli Z, Kittler R, Yatsenko A, Carmell M, Orth K, Amatruda JF, et al. GCNA Preserves Genome Integrity and Fertility Across Species. Developmental Cell. PMID 31839537 DOI: 10.1016/j.devcel.2019.11.007  0.01
2019 De Souza Santos M, Orth K. The Role of the Type III Secretion System in the Intracellular Lifestyle of Enteric Pathogens. Microbiology Spectrum. 7. PMID 31152523 DOI: 10.1128/microbiolspec.BAI-0008-2019  0.01
2019 Stefanius K, Servage K, de Souza Santos M, Gray HF, Toombs JE, Chimalapati S, Kim MS, Malladi VS, Brekken R, Orth K. Human pancreatic cancer cell exosomes, but not human normal cell exosomes, act as an initiator in cell transformation. Elife. 8. PMID 31134894 DOI: 10.7554/eLife.40226  0.01
2019 De Nisco NJ, Neugent M, Mull J, Chen L, Kuprasertkul A, de Souza Santos M, Palmer KL, Zimmern P, Orth K. Direct Detection of Tissue-Resident Bacteria and Chronic Inflammation in the Bladder Wall of Postmenopausal Women with Recurrent Urinary Tract Infection. Journal of Molecular Biology. PMID 31002774 DOI: 10.1016/j.jmb.2019.04.008  0.01
2018 Moehlman AT, Casey AK, Servage K, Orth K, Krämer H. Adaptation to constant light requires Fic-mediated AMPylation of BiP to protect against reversible photoreceptor degeneration. Elife. 7. PMID 30015618 DOI: 10.7554/eLife.38752  0.01
2018 Orth K. My winding trail while fulfilling my love for science and family. The Journal of Biological Chemistry. PMID 29643182 DOI: 10.1074/jbc.AW118.003225  0.01
2018 Chimalapati S, de Souza Santos M, Servage K, De Nisco NJ, Dalia AB, Orth K. Natural transformation of: A rapid method to create genetic deletions. Journal of Bacteriology. PMID 29555695 DOI: 10.1128/JB.00032-18  0.01
2018 Casey AK, Moehlman AT, Zhang J, Servage KA, Krämer H, Orth K. Fic-mediated deAMPylation is not dependent on homodimerization and rescues toxic AMPylation in flies. The Journal of Biological Chemistry. 293: 1550. PMID 29414767 DOI: 10.1074/jbc.AAC118.001798  0.01
2018 De Nisco NJ, Rivera-Cancel G, Orth K. The Biochemistry of Sensing: Enteric Pathogens Regulate Type III Secretion in Response to Environmental and Host Cues. Mbio. 9. PMID 29339429 DOI: 10.1128/mBio.02122-17  0.01
2017 Casey AK, Moehlman AT, Zhang J, Servage KA, Krämer H, Orth K. Fic-mediated deAMPylation is not dependent on homo-dimerization and rescues toxic AMPylation in flies. The Journal of Biological Chemistry. PMID 29089387 DOI: 10.1074/jbc.M117.799296  0.01
2017 Casey AK, Orth K. Enzymes Involved in AMPylation and deAMPylation. Chemical Reviews. PMID 28819965 DOI: 10.1021/acs.chemrev.7b00145  0.01
2017 De Nisco NJ, Orth K, VanHook AM. Science Signaling Podcast for 16 May 2017: Vibrio rewires host cells. Science Signaling. 10. PMID 28512146 DOI: 10.1126/scisignal.aan5621  0.01
2017 Rivera-Cancel G, Orth K. Biochemical basis for activation of virulence genes by bile salts in Vibrio parahaemolyticus. Gut Microbes. 1-8. PMID 28129014 DOI: 10.1080/19490976.2017.1287655  0.01
2015 de Souza Santos M, Orth K. Subversion of the cytoskeleton by intracellular bacteria: lessons from Listeria, Salmonella and Vibrio. Cellular Microbiology. 17: 164-73. PMID 25440316 DOI: 10.1111/cmi.12399  0.01
2014 Woolery AR, Yu X, LaBaer J, Orth K. AMPylation of Rho GTPases subverts multiple host signaling processes. The Journal of Biological Chemistry. 289: 32977-88. PMID 25301945 DOI: 10.1074/jbc.M114.601310  0.01
2014 de Souza Santos M, Orth K. Intracellular Vibrio parahaemolyticus escapes the vacuole and establishes a replicative niche in the cytosol of epithelial cells. Mbio. 5: e01506-14. PMID 25205094 DOI: 10.1128/mBio.01506-14  0.01
2013 Orth K. An interview with Kim Orth. Trends in Biochemical Sciences. 38: 331-2. PMID 23768998 DOI: 10.1016/j.tibs.2013.05.002  0.01
2008 Laskowski-Arce MA, Orth K. Acanthamoeba castellanii promotes the survival of Vibrio parahaemolyticus. Applied and Environmental Microbiology. 74: 7183-8. PMID 18849458 DOI: 10.1128/AEM.01332-08  0.01
2007 Laskowski-Arce MA, Orth K. The elusive activity of the Yersinia protein kinase A kinase domain is revealed. Trends in Microbiology. 15: 437-40. PMID 17920275 DOI: 10.1016/j.tim.2007.09.002  0.01
2006 Fehr D, Casanova C, Liverman A, Blazkova H, Orth K, Dobbelaere D, Frey J, Burr SE. AopP, a type III effector protein of Aeromonas salmonicida, inhibits the NF-kappaB signalling pathway. Microbiology (Reading, England). 152: 2809-18. PMID 16946275 DOI: 10.1099/mic.0.28889-0  0.01
2003 Yoon S, Liu Z, Eyobo Y, Orth K. Yersinia effector YopJ inhibits yeast MAPK signaling pathways by an evolutionarily conserved mechanism. The Journal of Biological Chemistry. 278: 2131-5. PMID 12433923 DOI: 10.1074/jbc.M209905200  0.01
2002 Heussler VT, Rottenberg S, Schwab R, Küenzi P, Fernandez PC, McKellar S, Shiels B, Chen ZJ, Orth K, Wallach D, Dobbelaere DA. Hijacking of host cell IKK signalosomes by the transforming parasite Theileria. Science (New York, N.Y.). 298: 1033-6. PMID 12411708 DOI: 10.1126/science.1075462  0.01
2002 Orth K. Function of the Yersinia effector YopJ. Current Opinion in Microbiology. 5: 38-43. PMID 11834367  0.01
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