| Year |
Citation |
Score |
| 2022 |
Ruf WP, Palmer A, Dörfer L, Wiesner D, Buck E, Grozdanov V, Kassubek J, Dimou L, Ludolph AC, Huber-Lang M, Danzer KM. Thoracic trauma promotes alpha-Synuclein oligomerization in murine Parkinson's disease. Neurobiology of Disease. 105877. PMID 36162738 DOI: 10.1016/j.nbd.2022.105877 |
0.373 |
|
| 2022 |
Ruf WP, Meirelles JL, Danzer KM. Spreading of alpha-synuclein between different cell types. Behavioural Brain Research. 436: 114059. PMID 35995264 DOI: 10.1016/j.bbr.2022.114059 |
0.491 |
|
| 2021 |
Bhatia D, Grozdanov V, Ruf WP, Kassubek J, Ludolph AC, Weishaupt JH, Danzer KM. T-cell dysregulation is associated with disease severity in Parkinson's Disease. Journal of Neuroinflammation. 18: 250. PMID 34717679 DOI: 10.1186/s12974-021-02296-8 |
0.321 |
|
| 2020 |
Grozdanov V, Danzer KM. Intracellular Alpha-Synuclein and Immune Cell Function. Frontiers in Cell and Developmental Biology. 8: 562692. PMID 33178682 DOI: 10.3389/fcell.2020.562692 |
0.338 |
|
| 2020 |
Kiechle M, Grozdanov V, Danzer KM. The Role of Lipids in the Initiation of α-Synuclein Misfolding. Frontiers in Cell and Developmental Biology. 8: 562241. PMID 33042996 DOI: 10.3389/fcell.2020.562241 |
0.442 |
|
| 2019 |
Kiechle M, von Einem B, Höfs L, Voehringer P, Grozdanov V, Markx D, Parlato R, Wiesner D, Mayer B, Sakk O, Baumann B, Lukassen S, Liss B, Ekici AB, Ludolph AC, ... ... Danzer KM, et al. In Vivo Protein Complementation Demonstrates Presynaptic α-Synuclein Oligomerization and Age-Dependent Accumulation of 8-16-mer Oligomer Species. Cell Reports. 29: 2862-2874.e9. PMID 31775051 DOI: 10.1016/J.Celrep.2019.10.089 |
0.661 |
|
| 2019 |
Grozdanov V, Bousset L, Hoffmeister M, Bliederhaeuser C, Meier C, Madiona K, Pieri L, Kiechle M, McLean PJ, Kassubek J, Behrends C, Ludolph AC, Weishaupt JH, Melki R, Danzer KM. Increased immune activation by pathologic alpha-synuclein in Parkinson's Disease. Annals of Neurology. PMID 31343083 DOI: 10.1002/Ana.25557 |
0.65 |
|
| 2018 |
Grozdanov V, Danzer KM. Release and uptake of pathologic alpha-synuclein. Cell and Tissue Research. PMID 29411106 DOI: 10.1007/s00441-017-2775-9 |
0.526 |
|
| 2017 |
Zondler L, Kostka M, Garidel P, Heinzelmann U, Hengerer B, Mayer B, Weishaupt JH, Gillardon F, Danzer KM. Proteasome impairment by α-synuclein. Plos One. 12: e0184040. PMID 28945746 DOI: 10.1371/journal.pone.0184040 |
0.482 |
|
| 2017 |
von Einem B, Eschbach J, Kiechle M, Wahler A, Thal DR, McLean PJ, Weishaupt JH, Ludolph AC, von Arnim CAF, Danzer KM. The Golgi-localized, gamma ear-containing, ARF-binding (GGA) protein family alters alpha synuclein (α-syn) oligomerization and secretion. Aging. PMID 28722658 DOI: 10.18632/aging.101261 |
0.703 |
|
| 2017 |
Falkenburger B, Danzer K, Schneider A, Mollenhauer B. Recent developments in alpha-synuclein research – Clinical and preclinical data Basal Ganglia. 8: 22. DOI: 10.1016/J.Baga.2017.02.065 |
0.378 |
|
| 2016 |
Helferich AM, McLean PJ, Weishaupt JH, Danzer KM. Commentary: alpha-synuclein interacts with SOD1 and promotes its oligomerization. Journal of Neurology & Neuromedicine. 1: 28-30. PMID 27853754 |
0.67 |
|
| 2016 |
Koch Y, Helferich AM, Steinacker P, Oeckl P, Walther P, Weishaupt JH, Danzer KM, Otto M. Aggregated α-Synuclein Increases SOD1 Oligomerization in a Mouse Model of Amyotrophic Lateral Sclerosis. The American Journal of Pathology. 186: 2152-2161. PMID 27322773 DOI: 10.1016/j.ajpath.2016.04.008 |
0.401 |
|
| 2015 |
Stuendl A, Kunadt M, Kruse N, Bartels C, Moebius W, Danzer KM, Mollenhauer B, Schneider A. Induction of α-synuclein aggregate formation by CSF exosomes from patients with Parkinson's disease and dementia with Lewy bodies. Brain : a Journal of Neurology. PMID 26647156 DOI: 10.1093/brain/awv346 |
0.428 |
|
| 2015 |
Helferich AM, Ruf WP, Grozdanov V, Freischmidt A, Feiler MS, Zondler L, Ludolph AC, McLean PJ, Weishaupt JH, Danzer KM. α-synuclein interacts with SOD1 and promotes its oligomerization. Molecular Neurodegeneration. 10: 66. PMID 26643113 DOI: 10.1186/S13024-015-0062-3 |
0.677 |
|
| 2015 |
Bliederhaeuser C, Grozdanov V, Speidel A, Zondler L, Ruf WP, Bayer H, Kiechle M, Feiler MS, Freischmidt A, Brenner D, Witting A, Hengerer B, Fändrich M, Ludolph AC, Weishaupt JH, ... ... Danzer KM, et al. Age-dependent defects of alpha-synuclein oligomer uptake in microglia and monocytes. Acta Neuropathologica. PMID 26576561 DOI: 10.1007/s00401-015-1504-2 |
0.376 |
|
| 2015 |
von Einem B, Wahler A, Schips T, Serrano-Pozo A, Proepper C, Boeckers TM, Rueck A, Wirth T, Hyman BT, Danzer KM, Thal DR, von Arnim CA. The Golgi-Localized γ-Ear-Containing ARF-Binding (GGA) Proteins Alter Amyloid-β Precursor Protein (APP) Processing through Interaction of Their GAE Domain with the Beta-Site APP Cleaving Enzyme 1 (BACE1). Plos One. 10: e0129047. PMID 26053850 DOI: 10.1371/Journal.Pone.0129047 |
0.368 |
|
| 2015 |
Kunadt M, Eckermann K, Stuendl A, Gong J, Russo B, Strauss K, Rai S, Kügler S, Falomir Lockhart L, Schwalbe M, Krumova P, Oliveira LM, Bähr M, Möbius W, Levin J, ... ... Danzer KM, et al. Extracellular vesicle sorting of α-Synuclein is regulated by sumoylation. Acta Neuropathologica. 129: 695-713. PMID 25778619 DOI: 10.1007/S00401-015-1408-1 |
0.322 |
|
| 2015 |
Eschbach J, von Einem B, Müller K, Bayer H, Scheffold A, Morrison BE, Rudolph KL, Thal DR, Witting A, Weydt P, Otto M, Fauler M, Liss B, McLean PJ, Spada AR, ... ... Danzer KM, et al. Mutual exacerbation of peroxisome proliferator-activated receptor γ coactivator 1α deregulation and α-synuclein oligomerization. Annals of Neurology. 77: 15-32. PMID 25363075 DOI: 10.1002/Ana.24294 |
0.663 |
|
| 2014 |
Lázaro DF, Rodrigues EF, Langohr R, Shahpasandzadeh H, Ribeiro T, Guerreiro P, Gerhardt E, Kröhnert K, Klucken J, Pereira MD, Popova B, Kruse N, Mollenhauer B, Rizzoli SO, Braus GH, ... Danzer KM, et al. Systematic comparison of the effects of alpha-synuclein mutations on its oligomerization and aggregation. Plos Genetics. 10: e1004741. PMID 25393002 DOI: 10.1371/Journal.Pgen.1004741 |
0.476 |
|
| 2014 |
Grozdanov V, Bliederhaeuser C, Ruf WP, Roth V, Fundel-Clemens K, Zondler L, Brenner D, Martin-Villalba A, Hengerer B, Kassubek J, Ludolph AC, Weishaupt JH, Danzer KM. Inflammatory dysregulation of blood monocytes in Parkinson’s disease patients Acta Neuropathologica. 128: 651-663. PMID 25284487 DOI: 10.1007/s00401-014-1345-4 |
0.326 |
|
| 2014 |
McFarland NR, Dimant H, Kibuuka L, Ebrahimi-Fakhari D, Desjardins CA, Danzer KM, Danzer M, Fan Z, Schwarzschild MA, Hirst W, McLean PJ. Chronic treatment with novel small molecule Hsp90 inhibitors rescues striatal dopamine levels but not α-synuclein-induced neuronal cell loss. Plos One. 9: e86048. PMID 24465863 DOI: 10.1371/Journal.Pone.0086048 |
0.643 |
|
| 2014 |
Eschbach J, Danzer KM. α-Synuclein in Parkinson's disease: pathogenic function and translation into animal models. Neuro-Degenerative Diseases. 14: 1-17. PMID 24080741 DOI: 10.1159/000354615 |
0.44 |
|
| 2012 |
Danzer KM, Kranich LR, Ruf WP, Cagsal-Getkin O, Winslow AR, Zhu L, Vanderburg CR, McLean PJ. Exosomal cell-to-cell transmission of alpha synuclein oligomers. Molecular Neurodegeneration. 7: 42. PMID 22920859 DOI: 10.1186/1750-1326-7-42 |
0.733 |
|
| 2011 |
Vlad C, Lindner K, Karreman C, Schildknecht S, Leist M, Tomczyk N, Rontree J, Langridge J, Danzer K, Ciossek T, Petre A, Gross ML, Hengerer B, Przybylski M. Autoproteolytic fragments are intermediates in the oligomerization/aggregation of the Parkinson's disease protein alpha-synuclein as revealed by ion mobility mass spectrometry. Chembiochem : a European Journal of Chemical Biology. 12: 2740-4. PMID 22162214 DOI: 10.1002/Cbic.201100569 |
0.407 |
|
| 2011 |
Danzer KM, McLean PJ. Drug targets from genetics: α-synuclein. Cns & Neurological Disorders Drug Targets. 10: 712-23. PMID 21838671 DOI: 10.2174/187152711797247867 |
0.673 |
|
| 2011 |
Welander H, Bontha SV, Näsström T, Karlsson M, Nikolajeff F, Danzer K, Kostka M, Kalimo H, Lannfelt L, Ingelsson M, Bergström J. Gelsolin co-occurs with Lewy bodies in vivo and accelerates α-synuclein aggregation in vitro. Biochemical and Biophysical Research Communications. 412: 32-8. PMID 21798243 DOI: 10.1016/J.Bbrc.2011.07.027 |
0.559 |
|
| 2011 |
Danzer KM, Ruf WP, Putcha P, Joyner D, Hashimoto T, Glabe C, Hyman BT, McLean PJ. Heat-shock protein 70 modulates toxic extracellular α-synuclein oligomers and rescues trans-synaptic toxicity. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 326-36. PMID 20876215 DOI: 10.1096/Fj.10-164624 |
0.705 |
|
| 2011 |
Vlad C, Lindner K, Karreman C, Schildknecht S, Leist M, Tomczyk N, Rontree J, Langridge J, Danzer K, Ciossek T, Petre A, Gross ML, Hengerer B, Przybylski M. Inside Cover: Autoproteolytic Fragments Are Intermediates in the Oligomerization/Aggregation of the Parkinson's Disease Protein Alpha-Synuclein as Revealed by Ion Mobility Mass Spectrometry (ChemBioChem 18/2011) Chembiochem. 12: 2706-2706. DOI: 10.1002/Cbic.201190086 |
0.456 |
|
| 2010 |
Putcha P, Danzer KM, Kranich LR, Scott A, Silinski M, Mabbett S, Hicks CD, Veal JM, Steed PM, Hyman BT, McLean PJ. Brain-permeable small-molecule inhibitors of Hsp90 prevent alpha-synuclein oligomer formation and rescue alpha-synuclein-induced toxicity. The Journal of Pharmacology and Experimental Therapeutics. 332: 849-57. PMID 19934398 DOI: 10.1124/Jpet.109.158436 |
0.714 |
|
| 2009 |
Danzer KM, Krebs SK, Wolff M, Birk G, Hengerer B. Seeding induced by alpha-synuclein oligomers provides evidence for spreading of alpha-synuclein pathology. Journal of Neurochemistry. 111: 192-203. PMID 19686384 DOI: 10.1111/j.1471-4159.2009.06324.x |
0.471 |
|
| 2009 |
Hüls S, Högen T, Danzer K, Hengerer B, Vassallo N, Kretzschmar H, Giese A, Herms J. P4-222: Alpha-synuclein oligomers alter excitatory synaptic transmission via both pre- and postsynaptic mechanisms Alzheimer's & Dementia. 5: P495-P495. DOI: 10.1016/J.Jalz.2009.04.688 |
0.343 |
|
| 2008 |
Schnack C, Danzer KM, Hengerer B, Gillardon F. Protein array analysis of oligomerization-induced changes in alpha-synuclein protein-protein interactions points to an interference with Cdc42 effector proteins. Neuroscience. 154: 1450-7. PMID 18541383 DOI: 10.1016/j.neuroscience.2008.02.049 |
0.368 |
|
| 2008 |
Kostka M, Högen T, Danzer KM, Levin J, Habeck M, Wirth A, Wagner R, Glabe CG, Finger S, Heinzelmann U, Garidel P, Duan W, Ross CA, Kretzschmar H, Giese A. Single particle characterization of iron-induced pore-forming alpha-synuclein oligomers. The Journal of Biological Chemistry. 283: 10992-1003. PMID 18258594 DOI: 10.1074/Jbc.M709634200 |
0.418 |
|
| 2007 |
Danzer KM, Schnack C, Sutcliffe A, Hengerer B, Gillardon F. Functional protein kinase arrays reveal inhibition of p-21-activated kinase 4 by alpha-synuclein oligomers. Journal of Neurochemistry. 103: 2401-7. PMID 17883396 DOI: 10.1111/j.1471-4159.2007.04933.x |
0.382 |
|
| 2007 |
Danzer KM, Haasen D, Karow AR, Moussaud S, Habeck M, Giese A, Kretzschmar H, Hengerer B, Kostka M. Different species of alpha-synuclein oligomers induce calcium influx and seeding. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 9220-32. PMID 17715357 DOI: 10.1523/JNEUROSCI.2617-07.2007 |
0.75 |
|
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