Clive Page, PhD - Publications

Affiliations: 
1986- Institute of Pharmaceutical Science King's College London, London, UK 
Area:
Airway remodelling, Airway Diseases, Vascular Permeability
Website:
https://kclpure.kcl.ac.uk/portal/en/persons/clive-page(be7ffbc0-80e3-4606-9e96-0756b9e26fc4).html

209 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Calzetta L, Page C, Matera MG, Cazzola M, Rogliani P. Use of human airway smooth muscle in vitro and ex vivo to investigate drugs for the treatment of chronic obstructive respiratory disorders. British Journal of Pharmacology. PMID 37859567 DOI: 10.1111/bph.16272  0.51
2023 Cazzola M, Page C, Calzetta L, Singh D, Rogliani P, Matera MG. What role will ensifentrine play in the future treatment of chronic obstructive pulmonary disease patients? Implications from recent clinical trials. Immunotherapy. PMID 37779474 DOI: 10.2217/imt-2023-0136  0.504
2023 Stolfa I, Page C. Phosphodiesterase inhibitors and lung diseases. Advances in Pharmacology (San Diego, Calif.). 98: 55-81. PMID 37524492 DOI: 10.1016/bs.apha.2023.05.001  0.793
2023 Arkless KL, Fish M, Jennings A, Page CP, Shankar-Hari M, Pitchford SC. Investigation into P2Y Receptor function in platelets from patients with sepsis. Shock (Augusta, Ga.). PMID 37405876 DOI: 10.1097/SHK.0000000000002158  0.821
2023 Hoffman E, Urbano L, Martin A, Mahendran R, Patel A, Murnane D, Page C, Dailey LA, Forbes B, Hutter V. Profiling alveolar macrophage responses to inhaled compounds using in vitro high content image analysis. Toxicology and Applied Pharmacology. 116608. PMID 37385476 DOI: 10.1016/j.taap.2023.116608  0.784
2023 Hogwood J, Mulloy B, Lever R, Gray E, Page CP. Pharmacology of Heparin and Related Drugs: An Update. Pharmacological Reviews. 75: 328-379. PMID 36792365 DOI: 10.1124/pharmrev.122.000684  0.732
2023 Arkless KL, Pan D, Shankar-Hari M, Amison RT, Page CP, Rahman KM, Pitchford SC. Stimulation of platelet P2Y receptors by different endogenous nucleotides leads to functional selectivity via biased signalling. British Journal of Pharmacology. PMID 36694432 DOI: 10.1111/bph.16039  0.797
2022 Cazzola M, Page C, Rogliani P, Calzetta L, Matera MG. Dual bronchodilation for the treatment of COPD: From bench to bedside. British Journal of Clinical Pharmacology. PMID 35514240 DOI: 10.1111/bcp.15390  0.493
2022 Rogliani P, Page C, Calzetta L. Prescribing the right therapy for the treatment of chronic cough: a critical focus on current and investigational options. Expert Opinion On Pharmacotherapy. 1-4. PMID 35239465 DOI: 10.1080/14656566.2022.2047646  0.419
2021 Calzetta L, Pietroiusti A, Page C, Bussolati O, Chetta A, Facciolo F, Rogliani P. Multi-walled carbon nanotubes induce airway hyperresponsiveness in human bronchi by stimulating sensory C-fibers and increasing the release of neuronal acetylcholine. Expert Review of Respiratory Medicine. PMID 34498989 DOI: 10.1080/17476348.2021.1979395  0.428
2021 Man F, Nadkarni S, Kanabar V, E-Lacerda R, Gomes Ferreira S, Federici Canova D, Perretti M, Page CP, Riffo-Vasquez Y. A peptide derived from chaperonin 60.1, IRL201104, inhibits LPS-induced acute lung inflammation. American Journal of Physiology. Lung Cellular and Molecular Physiology. PMID 34431396 DOI: 10.1152/ajplung.00155.2021  0.761
2021 Amison RT, Page CP. Novel pharmacological therapies for the treatment of bronchial asthma. Minerva Medica. PMID 34236157 DOI: 10.23736/S0026-4806.21.07559-5  0.765
2021 Shah SA, Kanabar V, Riffo-Vasquez Y, Mohamed Z, Cleary SJ, Corrigan C, James AL, Elliot JG, Shute JK, Page CP, Pitchford SC. Platelets Independently Recruit into Asthmatic Lungs and Models of Allergic Inflammation via CCR3. American Journal of Respiratory Cell and Molecular Biology. PMID 33556295 DOI: 10.1165/rcmb.2020-0425OC  0.819
2020 Matera MG, Cazzola M, Page C. Prospects for COPD treatment. Current Opinion in Pharmacology. 56: 74-84. PMID 33333428 DOI: 10.1016/j.coph.2020.11.003  0.301
2020 Arnold S, Shah SA, Cleary SJ, OʼShaughnessy BG, Amison RT, Arkless K, Page CP, Pitchford SC. Red Blood Cells Elicit Platelet-Dependent Neutrophil Recruitment into Lung Airspaces. Shock (Augusta, Ga.). PMID 33306620 DOI: 10.1097/SHK.0000000000001705  0.816
2020 Manzo G, Hind CK, Ferguson PM, Amison RT, Hodgson-Casson AC, Ciazynska KA, Weller BJ, Clarke M, Lam C, Man RCH, Shaughnessy BGO, Clifford M, Bui TT, Drake AF, Atkinson RA, ... ... Page CP, et al. A pleurocidin analogue with greater conformational flexibility, enhanced antimicrobial potency and in vivo therapeutic efficacy. Communications Biology. 3: 697. PMID 33247193 DOI: 10.1038/s42003-020-01420-3  0.731
2020 Cleary SJ, Magnen M, Looney MR, Page CP. Update on animal models for COVID-19 research. British Journal of Pharmacology. PMID 33140409 DOI: 10.1111/bph.15266  0.634
2020 Tree JA, Turnbull JE, Buttigieg KR, Elmore MJ, Coombes N, Hogwood J, Mycroft-West CJ, Lima MA, Skidmore MA, Karlsson R, Chen YH, Zhang Y, Spalluto CM, Staples KJ, Yates EA, ... ... Page CP, et al. Unfractionated heparin inhibits live wild-type SARS-CoV-2 cell infectivity at therapeutically relevant concentrations. British Journal of Pharmacology. PMID 33125711 DOI: 10.1111/bph.15304  0.692
2020 Cazzola M, Page C, Rogliani P, Calzetta L, Matera MG. Multifaceted Beneficial Effects of Erdosteine: More than a Mucolytic Agent. Drugs. PMID 33025535 DOI: 10.1007/s40265-020-01412-x  0.515
2020 Muddle J, Kanabar V, Brown M, Page C, Forbes B. An in vitro bioassay for evaluating the effect of inhaled bronchodilators on airway smooth muscle. Pulmonary Pharmacology & Therapeutics. 101943. PMID 32889156 DOI: 10.1016/J.Pupt.2020.101943  0.307
2020 van Haren FMP, Page C, Laffey JG, Artigas A, Camprubi-Rimblas M, Nunes Q, Smith R, Shute J, Carroll M, Tree J, Carroll M, Singh D, Wilkinson T, Dixon B. Nebulised heparin as a treatment for COVID-19: scientific rationale and a call for randomised evidence. Critical Care (London, England). 24: 454. PMID 32698853 DOI: 10.1186/S13054-020-03148-2  0.4
2020 Hogwood J, Pitchford S, Mulloy B, Page C, Gray E. Heparin and non-anticoagulant heparin attenuate histone-induced inflammatory responses in whole blood. Plos One. 15: e0233644. PMID 32469940 DOI: 10.1371/Journal.Pone.0233644  0.725
2020 Cleary SJ, Pitchford SC, Amison RT, Carrington R, Robaina Cabrera CL, Magnen M, Looney MR, Gray E, Page CP. Animal models of mechanisms of SARS-CoV-2 infection and COVID-19 pathology. British Journal of Pharmacology. PMID 32462701 DOI: 10.1111/Bph.15143  0.768
2019 Riffo-Vasquez Y, Kanabar V, Keir SD, E-Lacerda RR, Man F, Jackson DJ, Corrigall V, Coates ARM, Page CP. Modulation of allergic inflammation in the lung by a peptide derived from mycobacteria tuberculosis chaperonin 60.1. Clinical and Experimental Allergy : Journal of the British Society For Allergy and Clinical Immunology. PMID 31845415 DOI: 10.1111/Cea.13550  0.738
2019 Cleary SJ, Rauzi F, Smyth E, Correia A, Hobbs C, Emerson M, Page CP, Pitchford SC. Radiolabelling and immunohistochemistry reveal platelet recruitment into lungs and platelet migration into airspaces following LPS inhalation in mice. Journal of Pharmacological and Toxicological Methods. 102: 106660. PMID 31838234 DOI: 10.1016/J.Vascn.2019.106660  0.747
2019 Calverley PM, Page C, Dal Negro RW, Fontana G, Cazzola M, Cicero AF, Pozzi E, Wedzicha JA. Effect of Erdosteine on COPD Exacerbations in COPD Patients with Moderate Airflow Limitation. International Journal of Chronic Obstructive Pulmonary Disease. 14: 2733-2744. PMID 31819405 DOI: 10.2147/Copd.S221852  0.325
2019 Dexter A, Steven RT, Patel A, Dailey LA, Taylor AJ, Ball D, Klapwijk J, Forbes B, Page CP, Bunch J. Imaging drugs, metabolites and biomarkers in rodent lung: a DESI MS strategy for the evaluation of drug-induced lipidosis. Analytical and Bioanalytical Chemistry. PMID 31776643 DOI: 10.1007/S00216-019-02151-Z  0.77
2019 Rogliani P, Matera MG, Facciolo F, Page C, Cazzola M, Calzetta L. Beclomethasone dipropionate, formoterol fumarate and glycopyrronium bromide: synergy of triple combination therapy on human airway smooth muscle ex vivo. British Journal of Pharmacology. PMID 31660611 DOI: 10.1111/Bph.14909  0.543
2019 Patel A, Hoffman E, Ball D, Klapwijk J, Steven RT, Dexter A, Bunch J, Baker D, Murnane D, Hutter V, Page C, Dailey LA, Forbes B. Comparison of Oral, Intranasal and Aerosol Administration of Amiodarone in Rats as a Model of Pulmonary Phospholipidosis. Pharmaceutics. 11. PMID 31319538 DOI: 10.3390/Pharmaceutics11070345  0.791
2019 Rogliani P, Matera MG, Calzetta L, Hanania NA, Page C, Rossi I, Andreadi A, Galli A, Coppola A, Cazzola M, Lauro D. Long-term observational study on the impact of GLP-1R agonists on lung function in diabetic patients. Respiratory Medicine. 154: 86-92. PMID 31228775 DOI: 10.1016/J.Rmed.2019.06.015  0.513
2019 Cazzola M, Calzetta L, Page C, Rogliani P, Matera MG. Thiol-Based Drugs in Pulmonary Medicine: Much More than Mucolytics. Trends in Pharmacological Sciences. PMID 31147200 DOI: 10.1016/J.Tips.2019.04.015  0.534
2019 Rogliani P, Matera MG, Page C, Puxeddu E, Cazzola M, Calzetta L. Efficacy and safety profile of mucolytic/antioxidant agents in chronic obstructive pulmonary disease: a comparative analysis across erdosteine, carbocysteine, and N-acetylcysteine. Respiratory Research. 20: 104. PMID 31133026 DOI: 10.1186/S12931-019-1078-Y  0.505
2019 Calzetta L, Rogliani P, Page C, Rinaldi B, Cazzola M, Matera MG. Pharmacological characterization of the interaction between tiotropium bromide and olodaterol on human bronchi and small airways. Pulmonary Pharmacology & Therapeutics. PMID 30876907 DOI: 10.1016/J.Pupt.2019.03.004  0.56
2019 Birring S, de Blasio F, Dicpinigaitis P, Fontana G, Lanata L, Page C, Saibene F, Zanasi A. Antitussive therapy: A role for levodropropizine. Pulmonary Pharmacology & Therapeutics. PMID 30872161 DOI: 10.1016/J.Pupt.2019.03.003  0.322
2019 Cleary SJ, Hobbs C, Amison RT, Arnold S, O'Shaughnessy BG, Lefrançais E, Mallavia B, Looney MR, Page CP, Pitchford SC. LPS-Induced Lung Platelet Recruitment Occurs Independently from Neutrophils, PSGL-1, and P-selectin. American Journal of Respiratory Cell and Molecular Biology. PMID 30768917 DOI: 10.1165/Rcmb.2018-0182Oc  0.825
2019 Cazzola M, Page C, Calzetta L, Matera MG. Ensifentrine (RPL554): an inhaled 'bifunctional' dual PDE3/4 inhibitor for the treatment of asthma and chronic obstructive pulmonary disease. Pharmaceutical Patent Analyst. PMID 30657422 DOI: 10.4155/Ppa-2018-0030  0.567
2019 Riffo-Vasquez Y, Kanabar-Raivadera V, Corrigall V, Page C. TNFAIP3/A20 expression in allergic asthma European Respiratory Journal. 54. DOI: 10.1183/13993003.Congress-2019.Pa2372  0.32
2018 Cleary SJ, Page CP. Gustav Born: pioneer in imaging platelet and leukocyte biology. Platelets. 1-5. PMID 30411649 DOI: 10.1080/09537104.2018.1535001  0.693
2018 Petito E, Amison RT, Piselli E, Shah S, Momi S, Pitchford SC, Gresele P, Page CP. A dichotomy in platelet activation: Evidence of different functional platelet responses to inflammatory versus haemostatic stimuli. Thrombosis Research. 172: 110-118. PMID 30408636 DOI: 10.1016/j.thromres.2018.10.019  0.82
2018 Cazzola M, Page C. An inhaled "bifunctional" dual PDE3/4 inhibitor provides additional short-term improvements in lung function compared to existing classes of bronchodilator: implications for future treatment of COPD. The European Respiratory Journal. 52. PMID 30385603 DOI: 10.1183/13993003.01675-2018  0.329
2018 Matera MG, Rinaldi B, Page C, Rogliani P, Cazzola M. Pharmacokinetic considerations concerning the use of bronchodilators in the treatment of chronic obstructive pulmonary disease. Expert Opinion On Drug Metabolism & Toxicology. 1-11. PMID 30261755 DOI: 10.1080/17425255.2018.1530215  0.37
2018 Carrington R, Jordan S, Pitchford SC, Page CP. Use of animal models in IPF research. Pulmonary Pharmacology & Therapeutics. 51: 73-78. PMID 29981850 DOI: 10.1016/j.pupt.2018.07.002  0.791
2018 Matera MG, Page C, Rinaldi B. β2-Adrenoceptor signalling bias in asthma and COPD and the potential impact on the comorbidities associated with these diseases. Current Opinion in Pharmacology. 40: 142-146. PMID 29763833 DOI: 10.1016/J.Coph.2018.04.012  0.313
2018 Cazzola M, Calzetta L, Rogliani P, Page C, Matera MG. Impact of doxofylline in COPD: A pair-wise meta-analysis. Pulmonary Pharmacology & Therapeutics. PMID 29705620 DOI: 10.1016/J.Pupt.2018.04.010  0.532
2018 Calzetta L, Rogliani P, Pistocchini E, Mattei M, Cito G, Alfonsi P, Page C, Matera MG. Combining long-acting bronchodilators with different mechanisms of action: A pharmacological approach to optimize bronchodilation of equine airways. Journal of Veterinary Pharmacology and Therapeutics. 41: 546-554. PMID 29582435 DOI: 10.1111/Jvp.12504  0.538
2018 Amison RT, Jamshidi S, Rahman KM, Page CP, Pitchford SC. Diverse signaling of the platelet P2Yreceptor leads to a dichotomy in platelet function. European Journal of Pharmacology. PMID 29534999 DOI: 10.1016/j.ejphar.2018.03.014  0.816
2018 Hogwood J, Naggi A, Torri G, Page C, Rigsby P, Mulloy B, Gray E. The effect of increasing the sulfation level of chondroitin sulfate on anticoagulant specific activity and activation of the kinin system. Plos One. 13: e0193482. PMID 29494632 DOI: 10.1371/Journal.Pone.0193482  0.711
2018 Calzetta L, Rogliani P, Pistocchini E, Mattei M, Cito G, Alfonsi P, Page C, Matera MG. Effect of lipopolysaccharide on the responsiveness of equine bronchial tissue. Pulmonary Pharmacology & Therapeutics. 49: 88-94. PMID 29408044 DOI: 10.1016/J.Pupt.2018.01.010  0.542
2018 Calzetta L, Rogliani P, Page C, Roncada P, Pistocchini E, Soggiu A, Piras C, Urbani A, Matera MG. Clinical effect of corticosteroids in asthma-affected horses: A quantitative synthesis. Equine Veterinary Journal. 50: 594-601. PMID 29393535 DOI: 10.1111/Evj.12815  0.517
2018 Amison RT, Cleary S, Riffo-Vasquez Y, Bajwa M, Page CP, Pitchford SC. Platelets Play a Central Role in Sensitization to Allergen. American Journal of Respiratory Cell and Molecular Biology. PMID 29365287 DOI: 10.1165/Rcmb.2017-0401Oc  0.808
2018 Jacobson GA, Raidal S, Hostrup M, Calzetta L, Wood-Baker R, Farber MO, Page CP, Walters EH. Long-Acting β2-Agonists in Asthma: Enantioselective Safety Studies are Needed. Drug Safety. PMID 29332144 DOI: 10.1007/S40264-017-0631-1  0.471
2018 Cazzola M, Calzetta L, Page C, Rogliani P, Matera MG. Impact of erdosteine on chronic bronchitis and COPD: A meta-analysis. Pulmonary Pharmacology & Therapeutics. 48: 185-194. PMID 29233650 DOI: 10.1016/J.Pupt.2017.11.009  0.523
2018 Riffo-Vasquez Y, Venkatasamy R, Page CP. Steroid sparing effects of doxofylline. Pulmonary Pharmacology & Therapeutics. 48: 1-4. PMID 29031617 DOI: 10.1016/j.pupt.2017.10.008  0.333
2018 Shute JK, Calzetta L, Cardaci V, di Toro S, Page CP, Cazzola M. Inhaled nebulised unfractionated heparin improves lung function in moderate to very severe COPD: A pilot study. Pulmonary Pharmacology & Therapeutics. 48: 88-96. PMID 28986203 DOI: 10.1016/J.Pupt.2017.10.001  0.527
2018 Lacerda R, Vasquez Y, Anhê G, Page C. Late Breaking Abstract - Gender and asthma: Gender-dependent effects of obesity on allergic pulmonary inflammation European Respiratory Journal. DOI: 10.1183/13993003.Congress-2018.Oa3571  0.311
2017 Matera MG, Page C, Cazzola M. Doxofylline is not just another theophylline! International Journal of Chronic Obstructive Pulmonary Disease. 12: 3487-3493. PMID 29255355 DOI: 10.2147/Copd.S150887  0.328
2017 Dal Negro RW, Wedzicha JA, Iversen M, Fontana G, Page C, Cicero AF, Pozzi E, Calverley PMA. Effect of erdosteine on the rate and duration of COPD exacerbations: the RESTORE study. The European Respiratory Journal. 50. PMID 29025888 DOI: 10.1183/13993003.00711-2017  0.312
2017 Amison RT, O'Shaughnessy BG, Arnold S, Cleary SJ, Nandi M, Pitchford SC, Bragonzi A, Page CP. Platelet Depletion Impairs Host Defence to Pulmonary Infection with Pseudomonas aeruginosa in Mice. American Journal of Respiratory Cell and Molecular Biology. PMID 28957635 DOI: 10.1165/Rcmb.2017-0083Oc  0.813
2017 Shah SA, Page CP, Pitchford SC. Platelet-Eosinophil Interactions As a Potential Therapeutic Target in Allergic Inflammation and Asthma. Frontiers in Medicine. 4: 129. PMID 28848732 DOI: 10.3389/fmed.2017.00129  0.691
2017 Cazzola M, Rogliani P, Calzetta L, Lauro D, Page C, Matera MG. Targeting Mechanisms Linking COPD to Type 2 Diabetes Mellitus. Trends in Pharmacological Sciences. 38: 940-951. PMID 28784329 DOI: 10.1016/J.Tips.2017.07.003  0.501
2017 Amison RT, Arnold S, O'Shaughnessy BG, Cleary SJ, Ofoedu J, Idzko M, Page CP, Pitchford SC. Lipopolysaccharide (LPS) induced pulmonary neutrophil recruitment and platelet activation is mediated via the P2Y1 and P2Y14 receptors in mice. Pulmonary Pharmacology & Therapeutics. PMID 28487256 DOI: 10.1016/J.Pupt.2017.05.005  0.799
2017 Cazzola M, Calzetta L, Rinaldi B, Page C, Rosano G, Rogliani P, Matera MG. Management of Chronic Obstructive Pulmonary Disease in Patients with Cardiovascular Diseases. Drugs. 77: 721-732. PMID 28349353 DOI: 10.1007/S40265-017-0731-3  0.502
2017 Page C, Cazzola M. Bifunctional Drugs for the Treatment of Respiratory Diseases. Handbook of Experimental Pharmacology. 237: 197-212. PMID 27787715 DOI: 10.1007/164_2016_69  0.36
2017 Negro RWD, Wedzicha JA, Iversen MI, Fontana G, Page C, Cicero AF, Pozzi E, Calverley PMA. Effect of erdosteine on the rate and duration of COPD exacerbations: the RESTORE study (Reducing Exacerbations and Symptoms by Treatment with ORal Erdosteine) European Respiratory Journal. 50. DOI: 10.1183/1393003.Congress-2017.Pa675  0.317
2017 Cleary S, Arnold S, Hobbs C, Page C, Pitchford S. Neither P-selectin nor PSGL-1 are critical for lung platelet accumulation following LPS inhalation European Respiratory Journal. DOI: 10.1183/1393003.Congress-2017.Pa344  0.744
2017 Shah S, Vasquez YR, Page C, Pitchford S. Platelets roll and adhere to the vascular bed in response to allergen challenge in allergic mice European Respiratory Journal. DOI: 10.1183/1393003.Congress-2017.Oa4845  0.645
2017 O'Shaughnessy B, Amison R, Coates A, Page C. Assessing the synergistic effect of the enhancer compound HT61 on Tobramycin activity in a murine model of pulmonary infection European Respiratory Journal. DOI: 10.1183/1393003.Congress-2017.Oa4837  0.774
2016 Page C, O'Shaughnessy B, Barnes P. Pathogenesis of COPD and Asthma. Handbook of Experimental Pharmacology. PMID 27888348 DOI: 10.1007/164_2016_61  0.645
2016 Muddle J, Kirton SB, Parisini I, Muddle A, Murnane D, Ali J, Brown M, Page C, Forbes B. Predicting the Fine Particle Fraction of Dry Powder Inhalers Using Artificial Neural Networks. Journal of Pharmaceutical Sciences. PMID 27837967 DOI: 10.1016/J.Xphs.2016.10.002  0.661
2016 Lever R, Smailbegovic A, Riffo-Vasquez Y, Gray E, Hogwood J, Francis SM, Richardson NV, Page CP, Mulloy B. Biochemical and functional characterization of glycosaminoglycans released from degranulating rat peritoneal mast cells: Insights into the physiological role of endogenous heparin. Pulmonary Pharmacology & Therapeutics. PMID 27816772 DOI: 10.1016/J.Pupt.2016.11.002  0.706
2016 Patel A, Keir SD, Brown MB, Hider R, Jones SA, Page CP. Using Salt Counterions to Modify β2-Agonist Behavior in Vivo. Molecular Pharmaceutics. PMID 27568865 DOI: 10.1021/Acs.Molpharmaceut.6B00448  0.788
2016 Matera MG, Page C, Rogliani P, Calzetta L, Cazzola M. Therapeutic Monoclonal Antibodies for the Treatment of Chronic Obstructive Pulmonary Disease. Drugs. 76: 1257-70. PMID 27506851 DOI: 10.1007/S40265-016-0625-9  0.558
2016 Calzetta L, Orlandi A, Page C, Rogliani P, Rinaldi B, Rosano G, Cazzola M, Matera MG. Brain natriuretic peptide: Much more than a biomarker. International Journal of Cardiology. 221: 1031-1038. PMID 27447810 DOI: 10.1016/J.Ijcard.2016.07.109  0.535
2016 Kanabar V, Tedaldi L, Jiang J, Nie X, Panina I, Descroix K, Man F, Pitchford SC, Page CP, Wagner GK. Base-modified UDP-sugars reduce cell surface levels of P-selectin glycoprotein 1 (PSGL-1) on IL-1β-stimulated human monocytes. Glycobiology. PMID 27233805 DOI: 10.1093/Glycob/Cww053  0.764
2016 Thomson D, Moss C, Venkatasamy R, Panagos CG, Robinson J, Bavington CD, Hogwood J, Mulloy B, Uhrín D, Spina D, Page CP. Structural characterization and anti-inflammatory activity of two novel polysaccharides from the sea squirt, ascadellia aspersa. Pulmonary Pharmacology & Therapeutics. PMID 27220632 DOI: 10.1016/j.pupt.2016.05.001  0.693
2016 Riffo-Vasquez Y, Somani A, Man F, Amison R, Pitchford S, Page CP. A Non Anti-coagulant Fraction of Heparin Inhibits Leukocyte Diapedesis into the Lung by an Effect on Platelets. American Journal of Respiratory Cell and Molecular Biology. PMID 27181499 DOI: 10.1165/Rcmb.2015-0172Oc  0.826
2016 Patel A, Woods A, Riffo-Vasquez Y, Babin-Morgan A, Jones MC, Jones S, Sunassee K, Clark S, de Rosales RT, Page C, Spina D, Forbes B, Dailey LA. Lung inflammation does not affect the clearance kinetics of lipid nanocapsules following pulmonary administration. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 27180635 DOI: 10.1016/J.Jconrel.2016.05.024  0.797
2016 Jiang J, Kanabar V, Padilla B, Man F, Pitchford SC, Page CP, Wagner GK. Uncharged nucleoside inhibitors of β-1,4-galactosyltransferase with activity in cells. Chemical Communications (Cambridge, England). PMID 26882174 DOI: 10.1039/C5Cc09289B  0.765
2016 Clay E, Patacchini R, Trevisani M, Preti D, Branà MP, Spina D, Page C. Ozone-Induced Hypertussive Responses in Rabbits and Guinea Pigs. The Journal of Pharmacology and Experimental Therapeutics. 357: 73-83. PMID 26837703 DOI: 10.1124/Jpet.115.230227  0.688
2016 Mulloy B, Hogwood J, Gray E, Lever R, Page CP. Pharmacology of Heparin and Related Drugs. Pharmacological Reviews. 68: 76-141. PMID 26672027 DOI: 10.1124/Pr.115.011247  0.715
2016 Shute J, Calzetta L, Cardaci V, Toro SD, Page C, Cazzola M. A randomised double-blind placebo-controlled trial of the effect of inhaled heparin on lung function, hyperinflation and exercise capacity in patients with COPD European Respiratory Journal. 48. DOI: 10.1183/13993003.Congress-2016.Oa3311  0.539
2016 Clay E, Patacchini R, Trevisani M, Preti D, Branà MP, Spina D, Page C. Ozone-induced hypertussive responses in rabbits and Guinea pigs Journal of Pharmacology and Experimental Therapeutics. 357: 73-83. DOI: 10.1124/jpet.115.230227  0.657
2015 Cazzola M, Calzetta L, Page C, Jardim J, Chuchalin AG, Rogliani P, Matera MG. Influence of N-acetylcysteine on chronic bronchitis or COPD exacerbations: a meta-analysis. European Respiratory Review : An Official Journal of the European Respiratory Society. 24: 451-61. PMID 26324807 DOI: 10.1183/16000617.00002215  0.515
2015 Muddle J, Murnane D, Parisini I, Brown M, Page C, Forbes B. Interaction of Formulation and Device Factors Determine the In Vitro Performance of Salbutamol Sulphate Dry Powders for Inhalation. Journal of Pharmaceutical Sciences. 104: 3861-9. PMID 26220184 DOI: 10.1002/Jps.24599  0.643
2015 Idzko M, Pitchford S, Page C. Role of platelets in allergic airway inflammation. The Journal of Allergy and Clinical Immunology. 135: 1416-23. PMID 26051948 DOI: 10.1016/J.Jaci.2015.04.028  0.452
2015 Morris A, Wang B, Waern I, Venkatasamy R, Page C, Schmidt EP, Wernersson S, Li JP, Spina D. The role of heparanase in pulmonary cell recruitment in response to an allergic but not non-allergic stimulus. Plos One. 10: e0127032. PMID 26039697 DOI: 10.1371/Journal.Pone.0127032  0.45
2015 Spina D, Page C. Editorial overview: Respiratory: Cough: a burning issue. Current Opinion in Pharmacology. 22: iv. PMID 26013559 DOI: 10.1016/J.Coph.2015.05.006  0.32
2015 Keir SD, Spina D, Page CP. Bradykinin and capsaicin induced airways obstruction in the guinea pig are platelet dependent. Pulmonary Pharmacology & Therapeutics. 33: 25-31. PMID 26006082 DOI: 10.1016/j.pupt.2015.05.004  0.352
2015 Hoffman E, Kumar A, Kanabar V, Arno M, Preux L, Millar V, Page C, Collins H, Mudway I, Dailey LA, Forbes B. In Vitro Multiparameter Assay Development Strategy toward Differentiating Macrophage Responses to Inhaled Medicines. Molecular Pharmaceutics. 12: 2675-87. PMID 25941945 DOI: 10.1021/Acs.Molpharmaceut.5B00048  0.353
2015 Calzetta L, Luongo L, Cazzola M, Page C, Rogliani P, Facciolo F, Maione S, Capuano A, Rinaldi B, Matera MG. Contribution of sensory nerves to LPS-induced hyperresponsiveness of human isolated bronchi. Life Sciences. 131: 44-50. PMID 25914087 DOI: 10.1016/J.Lfs.2015.03.023  0.502
2015 Calzetta L, Cazzola M, Page CP, Rogliani P, Facciolo F, Matera MG. Pharmacological characterization of the interaction between the dual phosphodiesterase (PDE) 3/4 inhibitor RPL554 and glycopyrronium on human isolated bronchi and small airways. Pulmonary Pharmacology & Therapeutics. 32: 15-23. PMID 25899618 DOI: 10.1016/J.Pupt.2015.03.007  0.474
2015 Makwana R, Venkatasamy R, Spina D, Page C. The effect of phytocannabinoids on airway hyper-responsiveness, airway inflammation, and cough. The Journal of Pharmacology and Experimental Therapeutics. 353: 169-80. PMID 25655949 DOI: 10.1124/Jpet.114.221283  0.345
2015 Pan D, Amison RT, Riffo-Vasquez Y, Spina D, Cleary SJ, Wakelam MJ, Page CP, Pitchford SC, Welch HC. P-Rex and Vav Rac-GEFs in platelets control leukocyte recruitment to sites of inflammation. Blood. 125: 1146-58. PMID 25538043 DOI: 10.1182/Blood-2014-07-591040  0.821
2015 Amison RT, Momi S, Morris A, Manni G, Keir S, Gresele P, Page CP, Pitchford SC. RhoA signaling through platelet P2Y₁ receptor controls leukocyte recruitment in allergic mice. The Journal of Allergy and Clinical Immunology. 135: 528-38. PMID 25445826 DOI: 10.1016/j.jaci.2014.09.032  0.804
2015 Dailey LA, Hernández-Prieto R, Casas-Ferreira AM, Jones MC, Riffo-Vasquez Y, Rodríguez-Gonzalo E, Spina D, Jones SA, Smith NW, Forbes B, Page C, Legido-Quigley C. Adenosine monophosphate is elevated in the bronchoalveolar lavage fluid of mice with acute respiratory toxicity induced by nanoparticles with high surface hydrophobicity. Nanotoxicology. 9: 106-15. PMID 24621376 DOI: 10.3109/17435390.2014.894150  0.308
2015 Cleary SJ, Page CP. Exploring dual PDE3/4 inhibition in the treatment of airway diseases Drugs of the Future. 40: 301-310. DOI: 10.1358/Dof.2015.040.05.2310563  0.681
2015 Mulloy B, Hogwood J, Gray E, Lever R, Page CP. Pharmacology of Heparin and Related Drugs Pharmacological Reviews. 68: 76-141. DOI: 10.1124/pr.115.011247  0.68
2014 Cazzola M, Calzetta L, Page CP, Rogliani P, Facciolo F, Gavaldà A, Matera MG. Pharmacological characterization of the interaction between aclidinium bromide and formoterol fumarate on human isolated bronchi. European Journal of Pharmacology. 745: 135-43. PMID 25446566 DOI: 10.1016/j.ejphar.2014.10.025  0.438
2014 Panagos CG, Thomson DS, Moss C, Hughes AD, Kelly MS, Liu Y, Chai W, Venkatasamy R, Spina D, Page CP, Hogwood J, Woods RJ, Mulloy B, Bavington CD, Uhrín D. Fucosylated chondroitin sulfates from the body wall of the sea cucumber Holothuria forskali: conformation, selectin binding, and biological activity. The Journal of Biological Chemistry. 289: 28284-98. PMID 25147180 DOI: 10.1074/Jbc.M114.572297  0.71
2014 Matera MG, Page C, Cazzola M. PDE inhibitors currently in early clinical trials for the treatment of asthma. Expert Opinion On Investigational Drugs. 23: 1267-75. PMID 24865624 DOI: 10.1517/13543784.2014.921157  0.357
2014 Page C, Pitchford S. Platelets and allergic inflammation. Clinical and Experimental Allergy : Journal of the British Society For Allergy and Clinical Immunology. 44: 901-13. PMID 24708345 DOI: 10.1111/Cea.12322  0.496
2014 Page C, Cazzola M. Bifunctional drugs for the treatment of asthma and chronic obstructive pulmonary disease. The European Respiratory Journal. 44: 475-82. PMID 24696121 DOI: 10.1183/09031936.00003814  0.366
2014 Jones MC, Jones SA, Riffo-Vasquez Y, Spina D, Hoffman E, Morgan A, Patel A, Page C, Forbes B, Dailey LA. Quantitative assessment of nanoparticle surface hydrophobicity and its influence on pulmonary biocompatibility. Journal of Controlled Release : Official Journal of the Controlled Release Society. 183: 94-104. PMID 24657808 DOI: 10.1016/J.Jconrel.2014.03.022  0.769
2014 Riffo-Vasquez Y, Man F, Page CP. Doxofylline, a novofylline inhibits lung inflammation induced by lipopolysacharide in the mouse. Pulmonary Pharmacology & Therapeutics. 27: 170-8. PMID 24456641 DOI: 10.1016/J.Pupt.2014.01.001  0.764
2014 Cazzola M, Calzetta L, Page CP, Matera MG. Use of indacaterol for the treatment of COPD: a pharmacokinetic evaluation. Expert Opinion On Drug Metabolism & Toxicology. 10: 129-37. PMID 24295085 DOI: 10.1517/17425255.2014.865723  0.436
2014 Calzetta L, Passeri D, Kanabar V, Rogliani P, Page C, Cazzola M, Matera MG, Orlandi A. Brain natriuretic peptide protects against hyperresponsiveness of human asthmatic airway smooth muscle via an epithelial cell-dependent mechanism. American Journal of Respiratory Cell and Molecular Biology. 50: 493-501. PMID 24074453 DOI: 10.1165/Rcmb.2013-0119Oc  0.546
2014 Cazzola M, Page C. Long-acting bronchodilators in COPD: where are we now and where are we going? Breathe. 10: 110-120. DOI: 10.1183/20734735.014813  0.332
2013 Franciosi LG, Diamant Z, Banner KH, Zuiker R, Morelli N, Kamerling IM, de Kam ML, Burggraaf J, Cohen AF, Cazzola M, Calzetta L, Singh D, Spina D, Walker MJ, Page CP. Efficacy and safety of RPL554, a dual PDE3 and PDE4 inhibitor, in healthy volunteers and in patients with asthma or chronic obstructive pulmonary disease: findings from four clinical trials. The Lancet. Respiratory Medicine. 1: 714-27. PMID 24429275 DOI: 10.1016/S2213-2600(13)70187-5  0.521
2013 Page C. Heparin and related drugs: beyond anticoagulant activity. Isrn Pharmacology. 2013: 910743. PMID 23984092 DOI: 10.1155/2013/910743  0.372
2013 Page C, Pitchford S. Neutrophil and platelet complexes and their relevance to neutrophil recruitment and activation. International Immunopharmacology. 17: 1176-84. PMID 23810443 DOI: 10.1016/J.Intimp.2013.06.004  0.444
2013 Calzetta L, Page CP, Spina D, Cazzola M, Rogliani P, Facciolo F, Matera MG. Effect of the mixed phosphodiesterase 3/4 inhibitor RPL554 on human isolated bronchial smooth muscle tone. The Journal of Pharmacology and Experimental Therapeutics. 346: 414-23. PMID 23766543 DOI: 10.1124/jpet.113.204644  0.456
2013 Spina D, Page CP. Regulating cough through modulation of sensory nerve function in the airways. Pulmonary Pharmacology & Therapeutics. 26: 486-90. PMID 23524012 DOI: 10.1016/J.Pupt.2013.03.011  0.351
2013 Page C, Pitchford S. Platelets coming of age: implications for our understanding of allergic inflammation. American Journal of Respiratory and Critical Care Medicine. 187: 459-60. PMID 23457362 DOI: 10.1164/Rccm.201301-0085Ed  0.387
2013 Cazzola M, Page C, Matera MG. Long-acting muscarinic receptor antagonists for the treatment of respiratory disease. Pulmonary Pharmacology & Therapeutics. 26: 307-17. PMID 23274274 DOI: 10.1016/J.Pupt.2012.12.006  0.334
2012 Amison R, Page C, Pitchford S. Pharmacological modulation of the inflammatory actions of platelets. Handbook of Experimental Pharmacology. 447-68. PMID 22918742 DOI: 10.1007/978-3-642-29423-5_18  0.795
2012 Cazzola M, Calzetta L, Rogliani P, Lauro D, Novelli L, Page CP, Kanabar V, Matera MG. High glucose enhances responsiveness of human airways smooth muscle via the Rho/ROCK pathway. American Journal of Respiratory Cell and Molecular Biology. 47: 509-16. PMID 22652200 DOI: 10.1165/rcmb.2011-0449OC  0.442
2012 Cazzola M, Page CP, Calzetta L, Matera MG. Pharmacology and therapeutics of bronchodilators. Pharmacological Reviews. 64: 450-504. PMID 22611179 DOI: 10.1124/pr.111.004580  0.494
2012 Cazzola M, Page CP, Calzetta L, Matera MG. Emerging anti-inflammatory strategies for COPD. The European Respiratory Journal. 40: 724-41. PMID 22496331 DOI: 10.1183/09031936.00213711  0.525
2012 Brown RA, Leung E, Kankaanranta H, Moilanen E, Page CP. Effects of heparin and related drugs on neutrophil function. Pulmonary Pharmacology & Therapeutics. 25: 185-92. PMID 22327105 DOI: 10.1016/J.Pupt.2012.01.006  0.417
2012 Hewson CA, Patel S, Calzetta L, Campwala H, Havard S, Luscombe E, Clarke PA, Peachell PT, Matera MG, Cazzola M, Page C, Abraham WM, Williams CM, Clark JD, Liu WL, et al. Preclinical evaluation of an inhibitor of cytosolic phospholipase A2α for the treatment of asthma. The Journal of Pharmacology and Experimental Therapeutics. 340: 656-65. PMID 22160268 DOI: 10.1124/Jpet.111.186379  0.593
2012 van Mastbergen J, Jolas T, Allegra L, Page CP. The mechanism of action of doxofylline is unrelated to HDAC inhibition, PDE inhibition or adenosine receptor antagonism. Pulmonary Pharmacology & Therapeutics. 25: 55-61. PMID 22138191 DOI: 10.1016/J.Pupt.2011.10.007  0.394
2012 Makwana R, Gozzard N, Spina D, Page C. TNF-α-induces airway hyperresponsiveness to cholinergic stimulation in guinea pig airways. British Journal of Pharmacology. 165: 1978-91. PMID 21951209 DOI: 10.1111/J.1476-5381.2011.01675.X  0.362
2012 Babin AL, Cannet C, Gérard C, Saint-Mezard P, Page CP, Sparrer H, Matsuguchi T, Beckmann N. Bleomycin-induced lung injury in mice investigated by MRI: model assessment for target analysis. Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. 67: 499-509. PMID 21656559 DOI: 10.1002/mrm.23009  0.778
2011 Calzetta L, Spina D, Cazzola M, Page CP, Facciolo F, Rendina EA, Matera MG. Pharmacological characterization of adenosine receptors on isolated human bronchi. American Journal of Respiratory Cell and Molecular Biology. 45: 1222-31. PMID 21700958 DOI: 10.1165/Rcmb.2011-0056Oc  0.487
2011 Page CP, Spina D. Phosphodiesterase inhibitors in the treatment of inflammatory diseases. Handbook of Experimental Pharmacology. 391-414. PMID 21695650 DOI: 10.1007/978-3-642-17969-3_17  0.385
2011 Babin AL, Cannet C, Gérard C, Wyss D, Page CP, Beckmann N. Noninvasive assessment of bleomycin-induced lung injury and the effects of short-term glucocorticosteroid treatment in rats using MRI. Journal of Magnetic Resonance Imaging : Jmri. 33: 603-14. PMID 21563244 DOI: 10.1002/jmri.22476  0.776
2011 Page C. Paradoxical pharmacology: turning our pharmacological models upside down. Trends in Pharmacological Sciences. 32: 197-200. PMID 21458081 DOI: 10.1016/J.Tips.2011.02.006  0.326
2011 Matera MG, Calzetta L, Passeri D, Facciolo F, Rendina EA, Page C, Cazzola M, Orlandi A. Epithelium integrity is crucial for the relaxant activity of brain natriuretic peptide in human isolated bronchi. British Journal of Pharmacology. 163: 1740-54. PMID 21410689 DOI: 10.1111/J.1476-5381.2011.01339.X  0.526
2011 Cazzola M, Calzetta L, Page CP, Rinaldi B, Capuano A, Matera MG. Protein prenylation contributes to the effects of LPS on EFS-induced responses in human isolated bronchi. American Journal of Respiratory Cell and Molecular Biology. 45: 704-10. PMID 21278325 DOI: 10.1165/rcmb.2010-0306OC  0.466
2011 Matera MG, Calzetta L, Rogliani P, Bardaro F, Page CP, Cazzola M. Evaluation of the effects of the R- and S-enantiomers of salbutamol on equine isolated bronchi. Pulmonary Pharmacology & Therapeutics. 24: 221-6. PMID 21195788 DOI: 10.1016/j.pupt.2010.12.008  0.497
2011 Saihkay HN, Rickards KJ, Page CP, Ballinger JR. Validating 123I-metaiodobenzylguanidine as a platelet marker for non-invasive imaging in rabbits. Journal of Pharmacological and Toxicological Methods. 63: 69-78. PMID 20646985 DOI: 10.1016/j.vascn.2010.05.001  0.817
2011 Page C. New Drugs and Targets for Asthma and Chronic Obstructive Pulmonary Disease (CDPD) British Journal of Clinical Pharmacology. 71: 969-969. DOI: 10.1111/J.1365-2125.2010.03886.X  0.345
2011 Page C, Pitchford S, Spina D. Development of new drugs for the treatment of respiratory diseases: from concept to the clinic Journal of Drug Delivery Science and Technology. 21: 347-352. DOI: 10.1016/S1773-2247(11)50053-X  0.365
2010 Kornerup KN, Salmon GP, Pitchford SC, Liu WL, Page CP. Circulating platelet-neutrophil complexes are important for subsequent neutrophil activation and migration. Journal of Applied Physiology (Bethesda, Md. : 1985). 109: 758-67. PMID 20558756 DOI: 10.1152/japplphysiol.01086.2009  0.837
2010 Cazzola M, Floriani I, Page CP. The therapeutic efficacy of erdosteine in the treatment of chronic obstructive bronchitis: a meta-analysis of individual patient data. Pulmonary Pharmacology & Therapeutics. 23: 135-44. PMID 19854285 DOI: 10.1016/J.Pupt.2009.10.002  0.306
2009 Page C. The beta2 receptor and airway hyper-responsiveness: are sensory nerves involved? Thorax. 64: 738-9. PMID 19717706 DOI: 10.1136/Thx.2009.113506  0.342
2009 Spina D, Page C. Airway irritability--a burning issue? Current Opinion in Pharmacology. 9: 530-4. PMID 19625215 DOI: 10.1016/J.Coph.2009.06.019  0.329
2009 Page C, MacLean M. Novel pharmacological approaches to airway and pulmonary vascular disease. Current Opinion in Pharmacology. 9: 229-30. PMID 19442583 DOI: 10.1016/J.Coph.2009.04.003  0.361
2009 Dunkel B, Rickards KJ, Werling D, Page CP, Cunningham FM. Neutrophil and platelet activation in equine recurrent airway obstruction is associated with increased neutrophil CD13 expression, but not platelet CD41/61 and CD62P or neutrophil-platelet aggregate formation. Veterinary Immunology and Immunopathology. 131: 25-32. PMID 19362377 DOI: 10.1016/J.Vetimm.2009.03.004  0.402
2009 Spina D, McFadzean I, Bertram FK, Page CP. Peripheral mechanisms II: the pharmacology of peripherally active antitussive drugs. Handbook of Experimental Pharmacology. 155-86. PMID 18825340 DOI: 10.1007/978-3-540-79842-2_8  0.36
2008 Keir S, Page C. The rabbit as a model to study asthma and other lung diseases. Pulmonary Pharmacology & Therapeutics. 21: 721-30. PMID 18430597 DOI: 10.1016/J.Pupt.2008.01.005  0.391
2008 Matera MG, Calzetta L, Sanduzzi A, Page CP, Cazzola M. Effects of neuraminidase on equine isolated bronchi. Pulmonary Pharmacology & Therapeutics. 21: 624-9. PMID 18394940 DOI: 10.1016/J.Pupt.2008.02.003  0.546
2008 Tymvios C, Jones S, Moore C, Pitchford SC, Page CP, Emerson M. Real-time measurement of non-lethal platelet thromboembolic responses in the anaesthetized mouse. Thrombosis and Haemostasis. 99: 435-40. PMID 18278196 DOI: 10.1160/Th07-07-0479  0.345
2008 Pitchford SC, Momi S, Baglioni S, Casali L, Giannini S, Rossi R, Page CP, Gresele P. Allergen induces the migration of platelets to lung tissue in allergic asthma. American Journal of Respiratory and Critical Care Medicine. 177: 604-12. PMID 18096710 DOI: 10.1164/rccm.200702-214OC  0.37
2008 Hanania NA, Singh S, El-Wali R, Flashner M, Franklin AE, Garner WJ, Dickey BF, Parra S, Ruoss S, Shardonofsky F, O'Connor BJ, Page C, Bond RA. The safety and effects of the beta-blocker, nadolol, in mild asthma: an open-label pilot study. Pulmonary Pharmacology & Therapeutics. 21: 134-41. PMID 17703976 DOI: 10.1016/J.Pupt.2007.07.002  0.31
2007 Dunkel B, Rickards KJ, Page CP, Cunningham FM. Platelet activation in ponies with airway inflammation. Equine Veterinary Journal. 39: 557-61. PMID 18065316 DOI: 10.2746/042516407X217885  0.464
2007 Cazzola M, Matera MG, Rogliani P, Page C. Treating systemic effects of COPD. Trends in Pharmacological Sciences. 28: 544-50. PMID 17897727 DOI: 10.1016/J.Tips.2007.09.006  0.384
2007 Kornerup KN, Page CP. The role of platelets in the pathophysiology of asthma. Platelets. 18: 319-28. PMID 17654302 DOI: 10.1080/09537100701230436  0.817
2007 Lever R, Hefni A, Moffatt JD, Paul W, Page CP. Effect of tecastemizole on pulmonary and cutaneous allergic inflammatory responses. Clinical and Experimental Allergy : Journal of the British Society For Allergy and Clinical Immunology. 37: 909-17. PMID 17517105 DOI: 10.1111/J.1365-2222.2007.02730.X  0.342
2007 Karmouty-Quintana H, Cannet C, Sugar R, Fozard JR, Page CP, Beckmann N. Capsaicin-induced mucus secretion in rat airways assessed in vivo and non-invasively by magnetic resonance imaging. British Journal of Pharmacology. 150: 1022-30. PMID 17351665 DOI: 10.1038/Sj.Bjp.0707168  0.345
2006 Pitchford SC, Page CP. Platelet activation in asthma: integral to the inflammatory response. Clinical and Experimental Allergy : Journal of the British Society For Allergy and Clinical Immunology. 36: 399-401. PMID 16630144 DOI: 10.1111/J.1365-2222.2006.02462.X  0.406
2006 Lawson EC, Santulli RJ, Dyatkin AB, Ballentine SA, Abraham WM, Rudman S, Page CP, de Garavilla L, Damiano BP, Kinney WA, Maryanoff BE. Selection of a 2-azabicyclo[2.2.2]octane-based alpha4beta1 integrin antagonist as an inhaled anti-asthmatic agent. Bioorganic & Medicinal Chemistry. 14: 4208-16. PMID 16495061 DOI: 10.1016/j.bmc.2006.01.067  0.324
2006 Keir S, Boswell-Smith V, Spina D, Page C. Mechanism of adenosine-induced airways obstruction in allergic guinea pigs. British Journal of Pharmacology. 147: 720-8. PMID 16432507 DOI: 10.1038/Sj.Bjp.0706663  0.381
2006 Saihkay H, Page C, Ballinger J, Rickards K. P5 Validation of a platelet marker for use in non-invasive imaging studies in the rabbit Nuclear Medicine Communications. 27: 1024. DOI: 10.1097/00006231-200612000-00056  0.779
2005 Kornerup KN, Page CP, Moffatt JD. Pharmacological characterisation of the adenosine receptor mediating increased ion transport in the mouse isolated trachea and the effect of allergen challenge. British Journal of Pharmacology. 144: 1011-6. PMID 15685200 DOI: 10.1038/sj.bjp.0706133  0.782
2005 Pitchford SC, Momi S, Giannini S, Casali L, Spina D, Page CP, Gresele P. Platelet P-selectin is required for pulmonary eosinophil and lymphocyte recruitment in a murine model of allergic inflammation. Blood. 105: 2074-81. PMID 15528309 DOI: 10.1182/blood-2004-06-2282  0.365
2004 Johnson Z, Kosco-Vilbois MH, Herren S, Cirillo R, Muzio V, Zaratin P, Carbonatto M, Mack M, Smailbegovic A, Rose M, Lever R, Page C, Wells TN, Proudfoot AE. Interference with heparin binding and oligomerization creates a novel anti-inflammatory strategy targeting the chemokine system. Journal of Immunology (Baltimore, Md. : 1950). 173: 5776-85. PMID 15494530 DOI: 10.4049/Jimmunol.173.9.5776  0.368
2004 Rose MJ, Page C. Glycosaminoglycans and the regulation of allergic inflammation. Current Drug Targets. Inflammation and Allergy. 3: 221-5. PMID 15446270 DOI: 10.2174/1568010043343589  0.386
2004 Riffo-Vasquez Y, Spina D, Page C, Tormay P, Singh M, Henderson B, Coates A. Effect of Mycobacterium tuberculosis chaperonins on bronchial eosinophilia and hyper-responsiveness in a murine model of allergic inflammation Clinical & Experimental Allergy. 34: 712-719. PMID 15144461 DOI: 10.1111/J.1365-2222.2004.1931.X  0.34
2004 Rickards KJ, Page CP, Cunningham FM. Allergen challenge alters lymphocyte phosphodiesterase activity in horses with heaves. Pulmonary Pharmacology & Therapeutics. 17: 163-72. PMID 15123226 DOI: 10.1016/J.Pupt.2004.02.001  0.353
2004 Rickards KJ, Page CP, Hamblin AS, Goode NT, Cunningham FM. Biochemical and functional assessment of equine lymphocyte phosphodiesterases and protein kinase C. Veterinary Immunology and Immunopathology. 98: 153-65. PMID 15010224 DOI: 10.1016/J.Vetimm.2003.12.001  0.347
2004 El-Hashim AZ, Buchheit KH, Fozard J, Page C. Effect of the K+(ATP) channel opener, KCO912, on baseline and allergen induced airway hyperresponsiveness in allergic rabbits. European Journal of Pharmacology. 484: 351-6. PMID 14744622 DOI: 10.1016/J.Ejphar.2003.11.018  0.355
2004 Pitchford SC, Riffo-Vasquez Y, Sousa A, Momi S, Gresele P, Spina D, Page CP. Platelets are necessary for airway wall remodeling in a murine model of chronic allergic inflammation. Blood. 103: 639-47. PMID 14504080 DOI: 10.1182/blood-2003-05-1707  0.388
2003 Pitchford SC, Yano H, Lever R, Riffo-Vasquez Y, Ciferri S, Rose MJ, Giannini S, Momi S, Spina D, O'connor B, Gresele P, Page CP. Platelets are essential for leukocyte recruitment in allergic inflammation. The Journal of Allergy and Clinical Immunology. 112: 109-18. PMID 12847487 DOI: 10.1067/mai.2003.1514  0.321
2003 Rickards KJ, Page CP, Lees P, Gettinby G, Cunningham FM. In vitro and ex vivo effects of the phosphodiesterase 4 inhibitor, rolipram, on thromboxane production in equine blood. Journal of Veterinary Pharmacology and Therapeutics. 26: 123-30. PMID 12667182 DOI: 10.1046/J.1365-2885.2003.00450.X  0.414
2003 Adcock JJ, Douglas GJ, Garabette M, Gascoigne M, Beatch G, Walker M, Page CP. RSD931, a novel anti-tussive agent acting on airway sensory nerves. British Journal of Pharmacology. 138: 407-16. PMID 12569065 DOI: 10.1038/Sj.Bjp.0705056  0.315
2003 Gresele P, Page C, Fuster V, Vermylen J. Platelets in Thrombotic and Non-Thrombotic Disorders. Cambridge University Press 2002 - ISBN 0 521 80261 X Transfusion Medicine. 13: 57-58. DOI: 10.1046/J.1365-3148.2003.00411.X  0.414
2002 Page C, Lee LY. Summary: peripheral pharmacology of cough. Pulmonary Pharmacology & Therapeutics. 15: 217-9. PMID 12099767 DOI: 10.1006/Pupt.2002.0353  0.322
2002 Rickards KJ, Page CP, Lees P, Cunningham FM. Phosphodiesterase activity in neutrophils from horses with chronic obstructive pulmonary disease. Veterinary Immunology and Immunopathology. 76: 319-30. PMID 11044563 DOI: 10.1016/S0165-2427(00)00220-8  0.375
2001 Rickards KJ, Page CP, Lees P, Cunningham FM. Differential inhibition of equine neutrophil function by phosphodiesterase inhibitors. Journal of Veterinary Pharmacology and Therapeutics. 24: 275-81. PMID 11555183 DOI: 10.1046/J.1365-2885.2001.00344.X  0.424
2001 Lever R, Page C. Glycosaminoglycans, airways inflammation and bronchial hyperresponsiveness. Pulmonary Pharmacology & Therapeutics. 14: 249-254. PMID 11448151 DOI: 10.1006/Pupt.2001.0296  0.393
2001 Seeds EA, Page CP. Heparin inhibits allergen-induced eosinophil infiltration into guinea-pig lung via a mechanism unrelated to its anticoagulant activity. Pulmonary Pharmacology & Therapeutics. 14: 111-9. PMID 11273792 DOI: 10.1006/Pupt.2000.0277  0.454
2001 Woisin FE, Herd CM, Douglas GJ, Raynor K, Spina D, Mitchell HW, Page CP. Relationship of airway responsiveness with airway morphometry in normal and immunized rabbits. Pulmonary Pharmacology & Therapeutics. 14: 75-83. PMID 11273787 DOI: 10.1006/Pupt.2000.0265  0.319
2001 Tucker RC, Kagaya M, Page CP, Spina D. The endogenous cannabinoid agonist, anandamide stimulates sensory nerves in guinea-pig airways. British Journal of Pharmacology. 132: 1127-35. PMID 11226144 DOI: 10.1038/Sj.Bjp.0703906  0.318
2001 Lever R, Smailbegovic A, Page C. Role of glycosaminoglycans in inflammation Inflammopharmacology. 9: 165-169. DOI: 10.1163/156856001300248443  0.315
2000 Sullivan PJ, Jafar ZH, Harbinson PL, Restrick LJ, Costello JF, Page CP. Platelet dynamics following allergen challenge in allergic asthmatics Respiration. 67: 514-517. PMID 11070455 DOI: 10.1159/000067466  0.455
2000 Landells LJ, Spina D, Souness JE, O'Connor BJ, Page CP. A biochemical and functional assessment of monocyte phosphodiesterase activity in healthy and asthmatic subjects Pulmonary Pharmacology and Therapeutics. 13: 231-239. PMID 11003567 DOI: 10.1006/Pupt.2000.0248  0.317
2000 Perretti M, Page C. Heparin and inflammation: a new use for an old GAG? Gut. 47: 14-15. PMID 10861256 DOI: 10.1136/Gut.47.1.14  0.401
2000 Momi S, Emerson M, Paul W, Leone M, Mezzasoma AM, Del Soldato P, Page CP, Gresele P. Prevention of pulmonary thromboembolism by NCX 4016, a nitric oxide-releasing aspirin. European Journal of Pharmacology. 397: 177-85. PMID 10844112 DOI: 10.1016/S0014-2999(00)00223-5  0.311
2000 Fairbairn SM, Page CP, Lees P, Cunningham FM. Early neutrophil but not eosinophil or platelet recruitment to the lungs of allergic horses following antigen exposure. Clinical and Experimental Allergy : Journal of the British Society For Allergy and Clinical Immunology. 23: 821-8. PMID 10780888 DOI: 10.1111/j.1365-2222.1993.tb00259.x  0.312
2000 Woisin FE, Matsumoto T, Douglas GJ, Paul W, Whalley ET, Page CP. Effect of antagonists for NK(2)and B(2) receptors on antigen-induced airway responses in allergic rabbits. Pulmonary Pharmacology & Therapeutics. 13: 13-23. PMID 10718986 DOI: 10.1006/Pupt.1999.0226  0.345
2000 Page C. The role of proteoglycans in the regulation of airways inflammation and airways remodelling Journal of Allergy and Clinical Immunology. 105. PMID 10669535 DOI: 10.1016/S0091-6749(00)90054-X  0.341
1999 Emerson M, Momi S, Paul W, Alberti PF, Page C, Gresele P. Endogenous nitric oxide acts as a natural antithrombotic agent in vivo by inhibiting platelet aggregation in the pulmonary vasculature. Thrombosis and Haemostasis. 81: 961-966. DOI: 10.1055/S-0037-1614607  0.423
1998 Harrison S, Reddy S, Page CP, Spina D. Stimulation of airway sensory nerves by cyclosporin A and FK506 in guinea-pig isolated bronchus British Journal of Pharmacology. 125: 1405-1412. PMID 9884067 DOI: 10.1038/Sj.Bjp.0702198  0.305
1998 Page CP, Cotter T, Kilfeather S, Sullivan P, Spina D, Costello JF. Effect of chronic theophylline treatment on the methacholine dose-response curve in allergic asthmatic subjects European Respiratory Journal. 12: 24-29. PMID 9701409 DOI: 10.1183/09031936.98.12010024  0.38
1998 Marr KA, Lees P, Page CP, Cunningham FM. Inhaled leukotrienes cause bronchoconstriction and neutrophil accumulation in horses. Research in Veterinary Science. 64: 219-24. PMID 9690607 DOI: 10.1016/S0034-5288(98)90129-1  0.302
1997 Emerson M, Paul W, Ferlenga P, Semeraro C, Page C. Effects of dopamine and selective dopamine agonists upon platelet accumulation in the cerebral and pulmonary vasculature of the rabbit British Journal of Pharmacology. 122: 682-686. PMID 9375964 DOI: 10.1038/Sj.Bjp.0701432  0.38
1997 Ablett JM, Fairbairn SM, Page CP, Lees P, Cunningham FM. Influence of antigen challenge on platelet responsiveness in horses with chronic obstructive pulmonary disease. Equine Veterinary Journal. 29: 382-6. PMID 9306066 DOI: 10.1111/J.2042-3306.1997.TB03144.X  0.341
1997 Fairbairn SM, Marr KA, Lees P, Cunningham FM, Page CP. Effects of platelet activating factor on the distribution of radiolabelled leucocytes and platelets in normal horses and asymptomatic horses with chronic obstructive pulmonary disease. Research in Veterinary Science. 61: 107-13. PMID 8880978 DOI: 10.1016/S0034-5288(96)90083-1  0.348
1996 Seeds EA, Kilfeather S, Okiji S, Schoupe TS, Donigi-Gale D, Page CP. Role of lipoxygenase metabolites in platelet-activating factor- and antigen-induced bronchial hyperresponsiveness and eosinophil infiltration. European Journal of Pharmacology. 293: 369-76. PMID 8748690 DOI: 10.1016/0926-6917(95)90057-8  0.305
1996 Jaffar Z, Sullivan P, Page C, Costello J. Low-dose theophylline modulates T-lymphocyte activation in allergen-challenged asthmatics European Respiratory Journal. 9: 456-462. PMID 8730004 DOI: 10.1183/09031936.96.09030456  0.312
1994 Herd CM, Donigi-Gale D, Shoupe TS, Kilfeather SA, Okiji SA, Page CP. Effect of PF 10040 on PAF-induced airway responses in neonatally immunized rabbits. British Journal of Pharmacology. 111: 7-12. PMID 8012726 DOI: 10.1111/j.1476-5381.1994.tb14016.x  0.301
1994 Sullivan P, Jaffar Z, Page C, Costello J, Bekir S, Jeffery P. Anti-inflammatory effects of low-dose oral theophylline in atopic asthma The Lancet. 343: 1006-1008. PMID 7909049 DOI: 10.1016/S0140-6736(94)90127-9  0.353
1994 Manzini S, Perretti F, Abelli L, Evangelista S, Seeds EA, Page CP. Isbufylline, a new xanthine derivative, inhibits airway hyperresponsiveness and airway inflammation in guinea pigs. European Journal of Pharmacology. 249: 251-7. PMID 7507057 DOI: 10.1016/0014-2999(93)90519-N  0.302
1992 Page CP. The contribution of platelet-activating factor to allergen-induced eosinophil infiltration and bronchial hyperresponsiveness. Lipids. 26: 1280-2. PMID 1819716 DOI: 10.1007/BF02536548  0.344
1991 Coyle AJ, Spina D, Page CP. PAF-induced bronchial hyperresponsiveness in the rabbit: contribution of platelets and airway smooth muscle. British Journal of Pharmacology. 101: 31-8. PMID 2282464 DOI: 10.1111/j.1476-5381.1990.tb12084.x  0.353
1991 Page CP. The role of platelet activating factor in allergic respiratory disease. British Journal of Clinical Pharmacology. 99S-106S. PMID 2268512 DOI: 10.1111/J.1365-2125.1990.Tb05475.X  0.482
1991 Spina D, McKenniff MG, Coyle AJ, Seeds EA, Tramontana M, Perretti F, Manzini S, Page CP. Effect of capsaicin on PAF-induced bronchial hyperresponsiveness and pulmonary cell accumulation in the rabbit. British Journal of Pharmacology. 103: 1268-74. PMID 1878761 DOI: 10.1111/j.1476-5381.1991.tb12335.x  0.317
1990 Page C. The role of platelets in allergic disease Clinical and Experimental Allergy. 20: 339-340. PMID 2376020 DOI: 10.1111/J.1365-2222.1990.Tb02790.X  0.39
1989 Spina D, Coyle AJ, Page CP. The role of platelet activating factor in allergic inflammation. Pulmonary Pharmacology. 2: 13-9. PMID 2520484 DOI: 10.1016/S0952-0600(89)80004-3  0.341
1988 Arnoux B, Denjean A, Page CP, Nolibe D, Morley J, Benveniste J. Accumulation of platelets and eosinophils in baboon lung after paf-acether challenge. Inhibition by ketotifen. The American Review of Respiratory Disease. 137: 855-60. PMID 3354991 DOI: 10.1164/AJRCCM/137.4.855  0.386
1988 Page CP. The involvement of platelets in non-thrombotic processes Trends in Pharmacological Sciences. 9: 66-71. PMID 3072733 DOI: 10.1016/0165-6147(88)90120-4  0.311
1988 Beijer L, Botting J, Crook P, Oyekan AO, Page CP, Rylander R. The involvement of platelet activating factor in endotoxin-induced pulmonary platelet recruitment in the guinea-pig. British Journal of Pharmacology. 92: 803-8. PMID 2447993 DOI: 10.1111/j.1476-5381.1987.tb11384.x  0.346
1987 Robertson DN, Page CP. Effect of platelet agonists on airway reactivity and intrathoracic platelet accumulation. British Journal of Pharmacology. 92: 105-11. PMID 3664082 DOI: 10.1111/j.1476-5381.1987.tb11301.x  0.351
1986 Pretolani M, Page CP, Lefort J, Lagente V, Vargaftig BB. Pharmacological modulation of the respiratory and haematological changes accompanying active anaphylaxis in the guinea-pig. European Journal of Pharmacology. 125: 403-9. PMID 3732399 DOI: 10.1016/0014-2999(86)90796-X  0.335
1985 Pirotzky E, Page C, Morley J, Bidault J, Benveniste J. Vascular permeability induced by Paf-acether (platelet-activating factor) in the isolated perfused rat kidney. Inflammation Research. 16: 17-18. PMID 4003192 DOI: 10.1007/Bf01999630  0.324
1984 Page CP, Paul W, Morley J. Platelets and bronchospasm. International Archives of Allergy and Applied Immunology. 74: 347-50. PMID 6735490 DOI: 10.1159/000233571  0.321
1984 Dewar A, Archer CB, Paul W, Page CP, MacDonald DM, Morley J. Cutaneous and pulmonary histopathological responses to platelet activating factor (Paf-acether) in the guinea-pig. The Journal of Pathology. 144: 25-34. PMID 6481526 DOI: 10.1002/PATH.1711440104  0.343
1984 Barrett PA, Butler KD, Morley J, Page CP, Paul W, White AM. Inhibition by Heparin of Platelet Accumulation In Vivo Thrombosis and Haemostasis. 51: 366-370. DOI: 10.1055/S-0038-1661103  0.317
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