| Year |
Citation |
Score |
| 2024 |
Poluben L, Nouri M, Liang J, Chen S, Varkaris A, Ersoy-Fazlioglu B, Voznesensky O, Lee II, Qiu X, Cato L, Seo JH, Freedman ML, Sowalsky AG, Lack NA, Corey E, ... ... Brown M, et al. Increased nuclear factor I-mediated chromatin access drives transition to androgen receptor splice variant dependence in prostate cancer. Cell Reports. 44: 115089. PMID 39709604 DOI: 10.1016/j.celrep.2024.115089 |
0.782 |
|
| 2024 |
DiCiaccio B, Seehawer M, Li Z, Patmanidis A, Bui T, Foidart P, Nishida J, D'Santos CS, Papachristou EK, Papanastasiou M, Reiter AH, Qiu X, Li R, Jiang Y, Huang XY, ... ... Brown M, et al. ZBTB7A is a modulator of KDM5-driven transcriptional networks in basal breast cancer. Cell Reports. 43: 114991. PMID 39570746 DOI: 10.1016/j.celrep.2024.114991 |
0.63 |
|
| 2024 |
Safi R, Wardell SE, Watkinson P, Qin X, Lee M, Park S, Krebs T, Dolan EL, Blattler A, Tsuji T, Nayak S, Khater M, Fontanillo C, Newlin MA, Kirkland ML, ... ... Brown M, et al. Androgen receptor monomers and dimers regulate opposing biological processes in prostate cancer cells. Nature Communications. 15: 7675. PMID 39227594 DOI: 10.1038/s41467-024-52032-y |
0.345 |
|
| 2024 |
Venkadakrishnan VB, Presser AG, Singh R, Booker MA, Traphagen NA, Weng K, Voss NCE, Mahadevan NR, Mizuno K, Puca L, Idahor O, Ku SY, Bakht MK, Borah AA, Herbert ZT, ... ... Brown M, et al. Lineage-specific canonical and non-canonical activity of EZH2 in advanced prostate cancer subtypes. Nature Communications. 15: 6779. PMID 39117665 DOI: 10.1038/s41467-024-51156-5 |
0.357 |
|
| 2024 |
Hillis AL, Martin TD, Manchester HE, Högström J, Zhang N, Lecky E, Kozlova N, Lee J, Persky NS, Root DE, Brown M, Cichowski K, Elledge SJ, Muranen T, Fruman DA, et al. Targeting Cholesterol Biosynthesis with Statins Synergizes with AKT Inhibitors in Triple-Negative Breast Cancer. Cancer Research. PMID 39024548 DOI: 10.1158/0008-5472.CAN-24-0970 |
0.304 |
|
| 2024 |
Neeb A, Figueiredo I, Bogdan D, Cato L, Stober J, Jiménez-Vacas JM, Gourain V, Lee II, Seeger R, Muhle-Goll C, Gurel B, Welti J, Nava Rodrigues D, Rekowski J, Qiu X, ... ... Brown M, et al. Thio-2 inhibits key signaling pathways required for the development and progression of castration resistant prostate cancer. Molecular Cancer Therapeutics. PMID 38412481 DOI: 10.1158/1535-7163.MCT-23-0354 |
0.767 |
|
| 2024 |
Venkadakrishnan VB, Presser AG, Singh R, Booker MA, Traphagen NA, Weng K, Voss NC, Mahadevan NR, Mizuno K, Puca L, Idahor O, Ku SY, Bakht MK, Borah AA, Herbert ZT, ... ... Brown M, et al. Lineage-specific canonical and non-canonical activity of EZH2 in advanced prostate cancer subtypes. Research Square. PMID 38405800 DOI: 10.21203/rs.3.rs-3935288/v1 |
0.357 |
|
| 2024 |
Poluben L, Nouri M, Liang J, Varkaris A, Ersoy-Fazlioglu B, Voznesensky O, Lee II, Qiu X, Cato L, Seo JH, Freedman ML, Sowalsky AG, Lack NA, Corey E, Nelson PS, ... Brown M, et al. Increased chromatin accessibility drives transition to androgen receptor splice variant dependence in castration-resistant prostate cancer. Biorxiv : the Preprint Server For Biology. PMID 38260576 DOI: 10.1101/2024.01.10.575110 |
0.782 |
|
| 2023 |
Jovanović B, Temko D, Stevens LE, Seehawer M, Fassl A, Murphy K, Anand J, Garza K, Gulvady A, Qiu X, Harper NW, Daniels VW, Xiao-Yun H, Ge JY, Alečković M, ... ... Brown M, et al. Heterogeneity and transcriptional drivers of triple-negative breast cancer. Cell Reports. 42: 113564. PMID 38100350 DOI: 10.1016/j.celrep.2023.113564 |
0.573 |
|
| 2023 |
Wu G, Yoshida N, Liu J, Zhang X, Xiong Y, Heavican-Foral TB, Mandato E, Liu H, Nelson GM, Yang L, Chen R, Donovan KA, Jones MK, Roshal M, Zhang Y, ... ... Brown M, et al. TP63 fusions drive multicomplex enhancer rewiring, lymphomagenesis, and EZH2 dependence. Science Translational Medicine. 15: eadi7244. PMID 37729434 DOI: 10.1126/scitranslmed.adi7244 |
0.464 |
|
| 2022 |
Qiu X, Brown LG, Conner JL, Nguyen HM, Boufaied N, Abou Alaiwi S, Seo JH, El Zarif T, Bell C, O'Connor E, Hanratty B, Pomerantz M, Freedman ML, Brown M, Haffner MC, et al. Response to supraphysiological testosterone is predicted by a distinct androgen receptor cistrome. Jci Insight. 7. PMID 35603787 DOI: 10.1172/jci.insight.157164 |
0.68 |
|
| 2022 |
Qiu X, Boufaied N, Hallal T, Feit A, de Polo A, Luoma AM, Alahmadi W, Larocque J, Zadra G, Xie Y, Gu S, Tang Q, Zhang Y, Syamala S, Seo JH, ... ... Brown M, et al. MYC drives aggressive prostate cancer by disrupting transcriptional pause release at androgen receptor targets. Nature Communications. 13: 2559. PMID 35562350 DOI: 10.1038/s41467-022-30257-z |
0.719 |
|
| 2022 |
Kuznik NC, Solozobova V, Lee II, Jung N, Yang L, Nienhaus K, Ntim EA, Rottenberg JT, Muhle-Goll C, Kumar AR, Peravali R, Gräßle S, Gourain V, Deville C, Cato L, ... ... Brown M, et al. A chemical probe for BAG1 targets androgen receptor-positive prostate cancer through oxidative stress signaling pathway. Iscience. 25: 104175. PMID 35479411 DOI: 10.1016/j.isci.2022.104175 |
0.772 |
|
| 2022 |
DeCaprio JA, Brown M. David M. Livingston 1941-2021. Nature Cancer. 2: 1276-1277. PMID 35121923 DOI: 10.1038/s43018-021-00318-1 |
0.393 |
|
| 2022 |
Liao Y, Chen CH, Xiao T, de la Peña Avalos B, Dray EV, Cai C, Gao S, Shah N, Zhang Z, Feit A, Xue P, Liu Z, Yang M, Lee JH, Xu H, ... ... Brown M, et al. Inhibition of EZH2 transactivation function sensitizes solid tumors to genotoxic stress. Proceedings of the National Academy of Sciences of the United States of America. 119. PMID 35031563 DOI: 10.1073/pnas.2105898119 |
0.328 |
|
| 2021 |
Cejas P, Xie Y, Font-Tello A, Lim K, Syamala S, Qiu X, Tewari AK, Shah N, Nguyen HM, Patel RA, Brown L, Coleman I, Hackeng WM, Brosens L, Dreijerink KMA, ... ... Brown M, et al. Subtype heterogeneity and epigenetic convergence in neuroendocrine prostate cancer. Nature Communications. 12: 5775. PMID 34599169 DOI: 10.1038/s41467-021-26042-z |
0.668 |
|
| 2021 |
Tewari AK, Cheung ATM, Crowdis J, Conway JR, Camp SY, Wankowicz SA, Livitz DG, Park J, Lis RT, Bosma-Moody A, He MX, AlDubayan SH, Zhang Z, McKay RR, Leshchiner I, ... Brown M, et al. Molecular features of exceptional response to neoadjuvant anti-androgen therapy in high-risk localized prostate cancer. Cell Reports. 36: 109665. PMID 34496240 DOI: 10.1016/j.celrep.2021.109665 |
0.548 |
|
| 2021 |
Qiu X, Feit AS, Feiglin A, Xie Y, Kesten N, Taing L, Perkins J, Gu S, Li Y, Cejas P, Zhou N, Jeselsohn R, Brown M, Shirley Liu X, Long HW. CoBRA: Containerized Bioinformatics Workflow for Reproducible ChIP/ATAC-seq Analysis. Genomics, Proteomics & Bioinformatics. PMID 34284136 DOI: 10.1016/j.gpb.2020.11.007 |
0.572 |
|
| 2021 |
Liang J, Wang L, Poluben L, Nouri M, Arai S, Xie L, Voznesensky OS, Cato L, Yuan X, Russo JW, Long HW, Brown M, Chen S, Balk SP. Androgen receptor splice variant 7 functions independently of the full length receptor in prostate cancer cells. Cancer Letters. PMID 34256096 DOI: 10.1016/j.canlet.2021.07.013 |
0.781 |
|
| 2021 |
Watt AC, Cejas P, DeCristo MJ, Metzger-Filho O, Lam EYN, Qiu X, BrinJones H, Kesten N, Coulson R, Font-Tello A, Lim K, Vadhi R, Daniels VW, Montero J, Taing L, ... ... Brown M, et al. CDK4/6 inhibition reprograms the breast cancer enhancer landscape by stimulating AP-1 transcriptional activity. Nature Cancer. 2: 34-48. PMID 33997789 DOI: 10.1038/s43018-020-00135-y |
0.577 |
|
| 2021 |
Wu Z, Zhou J, Zhang X, Zhang Z, Xie Y, Liu JB, Ho ZV, Panda A, Qiu X, Cejas P, Cañadas I, Akarca FG, McFarland JM, Nagaraja AK, Goss LB, ... ... Brown M, et al. Reprogramming of the esophageal squamous carcinoma epigenome by SOX2 promotes ADAR1 dependence. Nature Genetics. PMID 33972779 DOI: 10.1038/s41588-021-00859-2 |
0.481 |
|
| 2021 |
Baca SC, Takeda DY, Seo JH, Hwang J, Ku SY, Arafeh R, Arnoff T, Agarwal S, Bell C, O'Connor E, Qiu X, Alaiwi SA, Corona RI, Fonseca MAS, Giambartolomei C, ... ... Brown M, et al. Reprogramming of the FOXA1 cistrome in treatment-emergent neuroendocrine prostate cancer. Nature Communications. 12: 1979. PMID 33785741 DOI: 10.1038/s41467-021-22139-7 |
0.402 |
|
| 2021 |
Tokheim C, Wang X, Timms RT, Zhang B, Mena EL, Wang B, Chen C, Ge J, Chu J, Zhang W, Elledge SJ, Brown M, Liu XS. Systematic characterization of mutations altering protein degradation in human cancers. Molecular Cell. PMID 33567269 DOI: 10.1016/j.molcel.2021.01.020 |
0.307 |
|
| 2021 |
Dhimolea E, de Matos Simoes R, Kansara D, Al'Khafaji A, Bouyssou J, Weng X, Sharma S, Raja J, Awate P, Shirasaki R, Tang H, Glassner BJ, Liu Z, Gao D, Bryan J, ... ... Brown M, et al. An Embryonic Diapause-like Adaptation with Suppressed Myc Activity Enables Tumor Treatment Persistence. Cancer Cell. PMID 33417832 DOI: 10.1016/j.ccell.2020.12.002 |
0.643 |
|
| 2020 |
Bagati A, Kumar S, Jiang P, Pyrdol J, Zou AE, Godicelj A, Mathewson ND, Cartwright ANR, Cejas P, Brown M, Giobbie-Hurder A, Dillon D, Agudo J, Mittendorf EA, Liu XS, et al. Integrin αvβ6-TGFβ-SOX4 Pathway Drives Immune Evasion in Triple-Negative Breast Cancer. Cancer Cell. PMID 33385331 DOI: 10.1016/j.ccell.2020.12.001 |
0.356 |
|
| 2020 |
Wan C, Keany MP, Dong H, Al-Alem LF, Pandya UM, Lazo S, Boehnke K, Lynch KN, Xu R, Zarrella DT, Gu S, Cejas P, Lim K, Long HW, Elias KM, ... ... Brown M, et al. Enhanced efficacy of simultaneous PD-1 and PD-L1 immune checkpoint blockade in high grade serous ovarian cancer. Cancer Research. PMID 33158814 DOI: 10.1158/0008-5472.CAN-20-1674 |
0.77 |
|
| 2020 |
Shah N, Kesten N, Font-Tello A, Chang MEK, Vadhi R, Lim K, Flory MR, Cejas P, Mohammed H, Long HW, Brown M. ERG-mediated coregulator complex formation maintains androgen receptor signaling in prostate cancer. Cancer Research. PMID 32934023 DOI: 10.1158/0008-5472.Can-20-2044 |
0.443 |
|
| 2020 |
Dhimolea E, de Matos Simoes R, Kansara D, Weng X, Sharma S, Awate P, Liu Z, Gao D, Mitsiades N, Schwab JH, Chen Y, Jeselsohn R, Culhane AC, Brown M, Georgakoudi I, et al. Pleiotropic mechanisms drive endocrine resistance in the three-dimensional bone microenvironment. Cancer Research. PMID 32859606 DOI: 10.1158/0008-5472.Can-20-0571 |
0.646 |
|
| 2020 |
Wang C, Sun D, Huang X, Wan C, Li Z, Han Y, Qin Q, Fan J, Qiu X, Xie Y, Meyer CA, Brown M, Tang M, Long H, Liu T, et al. Integrative analyses of single-cell transcriptome and regulome using MAESTRO. Genome Biology. 21: 198. PMID 32767996 DOI: 10.1186/S13059-020-02116-X |
0.34 |
|
| 2020 |
Shi S, Gu S, Han T, Zhang W, Huang L, Li Z, Pan D, Fu J, Ge J, Brown M, Zhang P, Jiang P, Wucherpfennig KW, Liu XS. Inhibition of MAN2A1 enhances tumor response to anti-PD-L1. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 32723834 DOI: 10.1158/1078-0432.Ccr-20-0778 |
0.723 |
|
| 2020 |
Fassl A, Brain C, Abu-Remaileh M, Stukan I, Butter D, Stepien P, Feit AS, Bergholz J, Michowski W, Otto T, Sheng Q, Loo A, Michael W, Tiedt R, DeAngelis C, ... ... Brown M, et al. Increased lysosomal biomass is responsible for the resistance of triple-negative breast cancers to CDK4/6 inhibition. Science Advances. 6: eabb2210. PMID 32704543 DOI: 10.1126/Sciadv.Abb2210 |
0.664 |
|
| 2020 |
Font-Tello A, Kesten N, Xie Y, Taing L, Varešlija D, Young LS, Hamid AA, Van Allen EM, Sweeney CJ, Gjini E, Lako A, Hodi FS, Bellmunt J, Brown M, Cejas P, et al. FiTAc-seq: fixed-tissue ChIP-seq for H3K27ac profiling and super-enhancer analysis of FFPE tissues. Nature Protocols. PMID 32591768 DOI: 10.1038/S41596-020-0340-6 |
0.532 |
|
| 2020 |
Chen CH, Zheng R, Tokheim C, Dong X, Fan J, Wan C, Tang Q, Brown M, Liu JS, Meyer CA, Liu XS. Determinants of transcription factor regulatory range. Nature Communications. 11: 2472. PMID 32424124 DOI: 10.1038/S41467-020-16106-X |
0.38 |
|
| 2020 |
Shu S, Wu HJ, Ge JY, Zeid R, Harris IS, Jovanović B, Murphy K, Wang B, Qiu X, Endress JE, Reyes J, Lim K, Font-Tello A, Syamala S, Xiao T, ... ... Brown M, et al. Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer. Molecular Cell. PMID 32416067 DOI: 10.1016/J.Molcel.2020.04.027 |
0.62 |
|
| 2020 |
Li Z, Wang B, Gu S, Jiang P, Sahu A, Chen CH, Han T, Shi S, Wang X, Traugh N, Liu H, Liu Y, Wu Q, Brown M, Xiao T, et al. CRISPR Screens Identify Essential Cell Growth Mediators in BRAF Inhibitor-resistant Melanoma. Genomics, Proteomics & Bioinformatics. PMID 32413516 DOI: 10.1016/J.Gpb.2020.02.002 |
0.332 |
|
| 2020 |
Ge JY, Shu S, Kwon M, Jovanović B, Murphy K, Gulvady A, Fassl A, Trinh A, Kuang Y, Heavey GA, Luoma A, Paweletz C, Thorner AR, Wucherpfennig KW, Qi J, ... Brown M, et al. Acquired resistance to combined BET and CDK4/6 inhibition in triple-negative breast cancer. Nature Communications. 11: 2350. PMID 32393766 DOI: 10.1038/S41467-020-16170-3 |
0.385 |
|
| 2020 |
Andreano KJ, Baker JG, Park S, Safi R, Artham S, Oesterreich S, Jeselsohn R, Brown M, Sammons S, Wardell SE, Chang CY, Norris JD, McDonnell DP. The dysregulated pharmacology of clinically relevant ESR1 mutants is normalized by ligand-activated WT receptor. Molecular Cancer Therapeutics. PMID 32381587 DOI: 10.1158/1535-7163.Mct-19-1148 |
0.687 |
|
| 2020 |
Tay RE, Olawoyin O, Cejas P, Xie Y, Meyer CA, Weng QY, Fisher DE, Long HW, Brown M, Kim HJ, Wucherpfennig KW. Hdac3 is an epigenetic inhibitor of the cytotoxicity program in CD8 T cells. The Journal of Experimental Medicine. 217. PMID 32374402 DOI: 10.1084/Jem.20191453 |
0.31 |
|
| 2020 |
Kotsopoulos J, McGee EE, Lozano-Esparza S, Garber JE, Ligibel J, Collins LC, Polyak K, Brown M, Narod S, Tamimi RM, Eliassen AH. Premenopausal plasma osteoprotegerin and breast cancer risk: a case-control analysis nested within the Nurses' Health Study II. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. PMID 32277005 DOI: 10.1158/1055-9965.Epi-19-1154 |
0.407 |
|
| 2020 |
Qin Q, Fan J, Zheng R, Wan C, Mei S, Wu Q, Sun H, Brown M, Zhang J, Meyer CA, Liu XS. Lisa: inferring transcriptional regulators through integrative modeling of public chromatin accessibility and ChIP-seq data. Genome Biology. 21: 32. PMID 32033573 DOI: 10.1186/S13059-020-1934-6 |
0.371 |
|
| 2020 |
Mandigo AC, McNair C, Ku K, Pang A, Guan YF, Holst J, Brown M, Kelly WK, Knudsen KE. Molecular underpinnings of RB status as a biomarker of poor outcome in advanced prostate cancer. Journal of Clinical Oncology. 38: 189-189. DOI: 10.1200/Jco.2020.38.6_Suppl.189 |
0.42 |
|
| 2020 |
Ma W, Hermida-Prado F, Guarducci C, Feit A, Nardone A, Cohen G, Pan W, Wei H, Li N, Brown M, Jeseslsohn R. Combination of fulvestrant and chemotherapy in ESR1 Y537S mutant breast cancer cells and potential synergy mechanism related to p53 wildtype. Journal of Clinical Oncology. 38: 1065-1065. DOI: 10.1200/Jco.2020.38.15_Suppl.1065 |
0.432 |
|
| 2020 |
Hill SJ, Lizotte P, Kesten N, Horowitz NS, Muto MG, Worley MJ, Feltmate CM, Berkowitz RS, Long H, Matulonis UA, Crum CP, Brown M, D'Andrea AD. Abstract PR06: Dissecting mechanisms of replication fork stabilization in patient-derived high-grade serous organoid cultures and their impact on therapeutic sensitivity and the immune-tumor interaction Clinical Cancer Research. 26. DOI: 10.1158/1557-3265.Ovca19-Pr06 |
0.598 |
|
| 2020 |
Fu X, Pereira R, Angelis CD, Nanda S, Qin L, Veeraraghavan J, Selenica P, Weigelt B, Reis-Filho JS, Nardone A, Jeselsohn R, Brown M, Rimawi MF, Osborne CK, Schiff R. Abstract PD7-01: Identification of a high FOXA1-induced pro-metastatic enhancer signature in endocrine-resistant and metastatic breast cancer Cancer Research. 80. DOI: 10.1158/1538-7445.Sabcs19-Pd7-01 |
0.717 |
|
| 2020 |
Fu X, Pereira R, Angelis CD, Nanda S, Qin L, Shea MJ, Mitchell T, Veeraraghavan J, Sethunath V, Gutierrez C, Győrffy B, Cohen O, Wagle N, Nardone A, Jeselsohn R, ... Brown M, et al. Abstract P6-04-02: Integrative cistromic/transcriptomic profiling identifies a high FOXA1/ER-activated pro-metastatic secretome in endocrine-resistant breast cancer Cancer Research. 80. DOI: 10.1158/1538-7445.Sabcs19-P6-04-02 |
0.709 |
|
| 2020 |
Brown M. Abstract DL-1: Essential Genes and Cistromes in Breast Cancer Cancer Research. 80. DOI: 10.1158/1538-7445.Sabcs19-Dl-1 |
0.518 |
|
| 2020 |
Stein S, Nardone A, Liu W, Cohen G, Guarducci C, Brown M, Jeselsohn R, Michor F. Abstract B16: Mathematical modeling identifies optimum palbociclib dosing schedules for the treatment of estrogen receptor-positive (ER+) breast cancer patients Cancer Research. 80. DOI: 10.1158/1538-7445.Camodels2020-B16 |
0.678 |
|
| 2019 |
Fu X, Pereira R, De Angelis C, Veeraraghavan J, Nanda S, Qin L, Cataldo ML, Sethunath V, Mehravaran S, Gutierrez C, Chamness GC, Feng Q, O'Malley BW, Selenica P, Weigelt B, ... ... Brown M, et al. FOXA1 upregulation promotes enhancer and transcriptional reprogramming in endocrine-resistant breast cancer. Proceedings of the National Academy of Sciences of the United States of America. PMID 31826955 DOI: 10.1073/Pnas.1911584116 |
0.727 |
|
| 2019 |
Fei T, Li W, Peng J, Xiao T, Chen CH, Wu A, Huang J, Zang C, Liu XS, Brown M. Deciphering essential cistromes using genome-wide CRISPR screens. Proceedings of the National Academy of Sciences of the United States of America. PMID 31727847 DOI: 10.1073/Pnas.1908155116 |
0.392 |
|
| 2019 |
Ponnusamy S, Asemota S, Schwartzberg LS, Guestini F, McNamara KM, Pierobon M, Font-Tello A, Qiu X, Xie Y, Rao PK, Thiyagarajan T, Grimes B, Johnson DL, Fleming MD, Pritchard FE, ... ... Brown M, et al. Androgen Receptor Is a Non-canonical Inhibitor of Wild-Type and Mutant Estrogen Receptors in Hormone Receptor-Positive Breast Cancers. Iscience. 21: 341-358. PMID 31698248 DOI: 10.1016/J.Isci.2019.10.038 |
0.474 |
|
| 2019 |
Cocce KJ, Jasper JS, Desautels TK, Everett L, Wardell S, Westerling T, Baldi R, Wright TM, Tavares K, Yllanes A, Bae Y, Blitzer JT, Logsdon C, Rakiec DP, Ruddy DA, ... ... Brown M, et al. The Lineage Determining Factor GRHL2 Collaborates with FOXA1 to Establish a Targetable Pathway in Endocrine Therapy-Resistant Breast Cancer. Cell Reports. 29: 889-903.e10. PMID 31644911 DOI: 10.1016/J.Celrep.2019.09.032 |
0.435 |
|
| 2019 |
Labbé DP, Zadra G, Yang M, Reyes JM, Lin CY, Cacciatore S, Ebot EM, Creech AL, Giunchi F, Fiorentino M, Elfandy H, Syamala S, Karoly ED, Alshalalfa M, Erho N, ... ... Brown M, et al. High-fat diet fuels prostate cancer progression by rewiring the metabolome and amplifying the MYC program. Nature Communications. 10: 4358. PMID 31554818 DOI: 10.1038/S41467-019-12298-Z |
0.708 |
|
| 2019 |
Shah N, Brown M. The Sly Oncogene: FOXA1 Mutations in Prostate Cancer. Cancer Cell. 36: 119-121. PMID 31408618 DOI: 10.1016/J.Ccell.2019.07.005 |
0.387 |
|
| 2019 |
Chi D, Singhal H, Li L, Xiao T, Liu W, Pun M, Jeselsohn R, He H, Lim E, Vadhi R, Rao P, Long H, Garber J, Brown M. Estrogen receptor signaling is reprogrammed during breast tumorigenesis. Proceedings of the National Academy of Sciences of the United States of America. PMID 31110002 DOI: 10.1073/Pnas.1819155116 |
0.772 |
|
| 2019 |
Venema CM, Bense RD, Steenbruggen TG, Nienhuis HH, Qiu SQ, van Kruchten M, Brown M, Tamimi RM, Hospers GAP, Schröder CP, Fehrmann RSN, de Vries EGE. Consideration of breast cancer subtype in targeting the androgen receptor. Pharmacology & Therapeutics. PMID 31077689 DOI: 10.1016/J.Pharmthera.2019.05.005 |
0.461 |
|
| 2019 |
Ligibel J, Dillon DA, Giobbie-Hurder A, McTiernan A, Frank ES, Cornwell M, Pun M, Campbell N, Dowling RJO, Chang MC, Tolaney SM, Chagpar AB, Yung R, Freedman RA, Dominici LS, ... ... Brown M, et al. Impact of a pre-operative exercise intervention on breast cancer proliferation and gene expression: Results from the Pre-Operative Health and Body (PreHAB) Study. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 31018921 DOI: 10.1158/1078-0432.Ccr-18-3143 |
0.652 |
|
| 2019 |
Saito Y, Li L, Coyaud E, Luna A, Sander C, Raught B, Asara JM, Brown M, Muthuswamy SK. LLGL2 rescues nutrient stress by promoting leucine uptake in ER breast cancer. Nature. PMID 30996345 DOI: 10.1038/S41586-019-1126-2 |
0.479 |
|
| 2019 |
Lee II, Kuznik NC, Rottenberg J, Brown M, Cato ACB. Bag-1L: a promising therapeutic target for androgen receptor-dependent prostate cancer. Journal of Molecular Endocrinology. PMID 30913537 DOI: 10.1530/Jme-19-0034 |
0.442 |
|
| 2019 |
Köster J, Brown M, Liu XS. A Bayesian model for single cell transcript expression analysis on MERFISH data. Bioinformatics (Oxford, England). 35: 995-1001. PMID 30875429 DOI: 10.1093/Bioinformatics/Bty718 |
0.743 |
|
| 2019 |
Kensler KH, Regan MM, Heng YJ, Baker GM, Pyle ME, Schnitt SJ, Hazra A, Kammler R, Thürlimann B, Colleoni M, Viale G, Brown M, Tamimi RM. Prognostic and predictive value of androgen receptor expression in postmenopausal women with estrogen receptor-positive breast cancer: results from the Breast International Group Trial 1-98. Breast Cancer Research : Bcr. 21: 30. PMID 30795773 DOI: 10.1186/S13058-019-1118-Z |
0.474 |
|
| 2019 |
Cato L, de Tribolet-Hardy J, Lee I, Rottenberg JT, Coleman I, Melchers D, Houtman R, Xiao T, Li W, Uo T, Sun S, Kuznik NC, Göppert B, Ozgun F, van Royen ME, ... ... Brown M, et al. ARv7 Represses Tumor-Suppressor Genes in Castration-Resistant Prostate Cancer. Cancer Cell. PMID 30773341 DOI: 10.1016/J.Ccell.2019.01.008 |
0.832 |
|
| 2019 |
Hinohara K, Wu HJ, Sébastien Vigneau, McDonald TO, Igarashi KJ, Yamamoto KN, Madsen T, Fassl A, Egri SB, Papanastasiou M, Ding L, Peluffo G, Cohen O, Kales SC, Lal-Nag M, ... ... Brown M, et al. KDM5 Histone Demethylase Activity Links Cellular Transcriptomic Heterogeneity to Therapeutic Resistance. Cancer Cell. 35: 330-332. PMID 30753830 DOI: 10.1016/j.ccell.2019.01.012 |
0.587 |
|
| 2019 |
Kensler KH, Eliassen AH, Rosner BA, Hankinson SE, Brown M, Tamimi RM. Pre-diagnostic sex hormone levels and survival among breast cancer patients. Breast Cancer Research and Treatment. PMID 30604001 DOI: 10.1007/S10549-018-05121-8 |
0.392 |
|
| 2019 |
Gu SS, Hu XS, Wang XS, Li Z, Traugh N, Bu X, Xing X, Freeman G, Brown M, Liu XS. Abstract A077: Microenvironmental factors shape resistance patterns to immune checkpoint blockade Cancer Immunology Research. 7. DOI: 10.1158/2326-6074.Cricimteatiaacr18-A077 |
0.767 |
|
| 2019 |
Guarducci C, Nardone A, Feiglin A, Migliaccio I, Malorni L, Bonechi M, Benelli M, Leo AD, Hodgson G, Shapiro G, Brown M, Jeselsohn R. Abstract PD7-12: Inhibition of CDK7 overcomes resistance to CDK4/6 inhibitors in hormone receptor positive breast cancer cells Cancer Research. 79. DOI: 10.1158/1538-7445.Sabcs18-Pd7-12 |
0.674 |
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| 2019 |
Jeselsohn R, Guo H, Rees R, Barry W, Barlett C, Tung N, Krop I, Brown M, Winer E. Abstract PD1-05: Results from the phase Ib/II clinical trial of bazedoxifene and palbociclib in hormone receptor positive metastatic breast cancer Cancer Research. 79. DOI: 10.1158/1538-7445.Sabcs18-Pd1-05 |
0.669 |
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| 2019 |
Abraham BJ, Reddy J, Fonseca MA, Klein IA, Afeyan LK, Corona RI, Cejas P, Segato F, Karlan BY, Gayther SA, Freedman ML, Noushmehr H, Brown M, Matulonis UA, Lawrenson K, et al. Abstract 2615: Systematic approaches to predict oncogenic transcriptional regulatory circuitries identify important nodes in high-grade serous ovarian cancer Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-2615 |
0.355 |
|
| 2019 |
Gu S, Hu X, Wang X, Jiang P, Li Z, Traugh N, Bu X, Xing X, Freeman GJ, Brown M, Liu XS. Abstract 3779: Clonal tracing reveals different mechanisms of resistance to immune checkpoint blockade Cancer Research. 79: 3779-3779. DOI: 10.1158/1538-7445.Am2019-3779 |
0.759 |
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| 2018 |
Fanning SW, Jeselsohn R, Dharmarajan V, Mayne CG, Karimi M, Buchwalter G, Houtman R, Toy W, Fowler CE, Han R, Lainé M, Carlson KE, Martin TA, Nowak J, Nwachukwu JC, ... Brown M, et al. The SERM/SERD bazedoxifene disrupts ESR1 helix 12 to overcome acquired hormone resistance in breast cancer cells. Elife. 7. PMID 30489256 DOI: 10.7554/Elife.37161 |
0.7 |
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| 2018 |
Hinohara K, Wu HJ, Vigneau S, McDonald TO, Igarashi KJ, Yamamoto KN, Madsen T, Fassl A, Egri SB, Papanastasiou M, Ding L, Peluffo G, Cohen O, Kales SC, Lal-Nag M, ... ... Brown M, et al. KDM5 Histone Demethylase Activity Links Cellular Transcriptomic Heterogeneity to Therapeutic Resistance. Cancer Cell. PMID 30472020 DOI: 10.1016/J.Ccell.2018.10.014 |
0.691 |
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| 2018 |
Zheng R, Wan C, Mei S, Qin Q, Wu Q, Sun H, Chen CH, Brown M, Zhang X, Meyer CA, Liu XS. Cistrome Data Browser: expanded datasets and new tools for gene regulatory analysis. Nucleic Acids Research. PMID 30462313 DOI: 10.1093/Nar/Gky1094 |
0.742 |
|
| 2018 |
Kensler KH, Poole EM, Heng YJ, Collins LC, Glass B, Beck AH, Hazra A, Rosner BA, Eliassen AH, Hankinson SE, Winer EP, Brown M, Tamimi RM. Androgen Receptor Expression and Breast Cancer Survival: Results From the Nurses' Health Studies. Journal of the National Cancer Institute. PMID 30445651 DOI: 10.1093/Jnci/Djy173 |
0.455 |
|
| 2018 |
Witwicki RM, Ekram MB, Qiu X, Janiszewska M, Shu S, Kwon M, Trinh A, Frias E, Ramadan N, Hoffman G, Yu K, Xie Y, McAllister G, McDonald R, Golji J, ... ... Brown M, et al. TRPS1 Is a Lineage-Specific Transcriptional Dependency in Breast Cancer. Cell Reports. 25: 1255-1267.e5. PMID 30380416 DOI: 10.1016/J.Celrep.2018.10.023 |
0.655 |
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| 2018 |
Kensler KH, Beca F, Baker GM, Heng YJ, Beck AH, Schnitt SJ, Hazra A, Rosner BA, Eliassen AH, Hankinson SE, Brown M, Tamimi RM. Androgen receptor expression in normal breast tissue and subsequent breast cancer risk. Npj Breast Cancer. 4: 33. PMID 30276234 DOI: 10.1038/s41523-018-0085-3 |
0.3 |
|
| 2018 |
Kuang Y, Siddiqui B, Hu J, Pun M, Cornwell M, Buchwalter G, Hughes ME, Wagle N, Kirschmeier P, Jänne PA, Paweletz CP, Lin NU, Krop IE, Barry WT, Winer EP, ... Brown M, et al. Unraveling the clinicopathological features driving the emergence of mutations in metastatic breast cancer. Npj Breast Cancer. 4: 22. PMID 30083595 DOI: 10.1038/s41523-018-0075-5 |
0.6 |
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| 2018 |
Xiao T, Li W, Wang X, Xu H, Yang J, Wu Q, Huang Y, Geradts J, Jiang P, Fei T, Chi D, Zang C, Liao Q, Rennhack J, Andrechek E, ... ... Brown M, et al. Estrogen-regulated feedback loop limits the efficacy of estrogen receptor-targeted breast cancer therapy. Proceedings of the National Academy of Sciences of the United States of America. PMID 29987050 DOI: 10.1073/Pnas.1722617115 |
0.773 |
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| 2018 |
Chen CH, Xiao T, Xu H, Jiang P, Meyer CA, Li W, Brown M, Liu XS. Improved design and analysis of CRISPR knockout screens. Bioinformatics (Oxford, England). PMID 29868757 DOI: 10.1093/Bioinformatics/Bty450 |
0.709 |
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| 2018 |
Cornwell M, Vangala M, Taing L, Herbert Z, Köster J, Li B, Sun H, Li T, Zhang J, Qiu X, Pun M, Jeselsohn R, Brown M, Liu XS, Long HW. VIPER: Visualization Pipeline for RNA-seq, a Snakemake workflow for efficient and complete RNA-seq analysis. Bmc Bioinformatics. 19: 135. PMID 29649993 DOI: 10.1186/S12859-018-2139-9 |
0.764 |
|
| 2018 |
Labbé DP, Brown M. Transcriptional Regulation in Prostate Cancer. Cold Spring Harbor Perspectives in Medicine. PMID 29530947 DOI: 10.1101/Cshperspect.A030437 |
0.726 |
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| 2018 |
Jeselsohn R, Bergholz JS, Pun M, Cornwell M, Liu W, Nardone A, Xiao T, Li W, Qiu X, Buchwalter G, Feiglin A, Abell-Hart K, Fei T, Rao P, Long H, ... ... Brown M, et al. Allele-Specific Chromatin Recruitment and Therapeutic Vulnerabilities of ESR1 Activating Mutations. Cancer Cell. 33: 173-186.e5. PMID 29438694 DOI: 10.1016/J.Ccell.2018.01.004 |
0.692 |
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| 2018 |
Singhal H, Greene ME, Zarnke AL, Laine M, Al Abosy R, Chang YF, Dembo AG, Schoenfelt K, Vadhi R, Qiu X, Rao P, Santhamma B, Nair HB, Nickisch KJ, Long HW, ... ... Brown M, et al. Progesterone receptor isoforms, agonists and antagonists differentially reprogram estrogen signaling. Oncotarget. 9: 4282-4300. PMID 29435103 DOI: 10.18632/Oncotarget.21378 |
0.46 |
|
| 2018 |
Jiang P, Lee W, Li X, Johnson C, Liu JS, Brown M, Aster JC, Liu XS. Genome-Scale Signatures of Gene Interaction from Compound Screens Predict Clinical Efficacy of Targeted Cancer Therapies. Cell Systems. PMID 29428415 DOI: 10.1016/J.Cels.2018.01.009 |
0.342 |
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| 2018 |
Wan L, Xu K, Wei Y, Zhang J, Han T, Fry C, Zhang Z, Wang YV, Huang L, Yuan M, Xia W, Chang WC, Huang WC, Liu CL, Chang YC, ... ... Brown M, et al. Phosphorylation of EZH2 by AMPK Suppresses PRC2 Methyltransferase Activity and Oncogenic Function. Molecular Cell. 69: 279-291.e5. PMID 29351847 DOI: 10.1016/J.Molcel.2017.12.024 |
0.401 |
|
| 2018 |
Pan D, Kobayashi A, Jiang P, Ferrari de Andrade L, Tay RE, Luoma A, Tsoucas D, Qiu X, Lim K, Rao P, Long HW, Yuan GC, Doench J, Brown M, Liu S, et al. A major chromatin regulator determines resistance of tumor cells to T cell-mediated killing. Science (New York, N.Y.). PMID 29301958 DOI: 10.1126/Science.Aao1710 |
0.368 |
|
| 2018 |
Fanning SW, Jeselsohn R, Dharmarajan V, Mayne CG, Karimi M, Buchwalter G, Houtman R, Toy W, Fowler CE, Han R, Lainé M, Carlson KE, Martin TA, Nowak J, Nwachukwu JC, ... ... Brown M, et al. Author response: The SERM/SERD bazedoxifene disrupts ESR1 helix 12 to overcome acquired hormone resistance in breast cancer cells Elife. DOI: 10.7554/Elife.37161.024 |
0.682 |
|
| 2018 |
Gu SSG, Li Z, Bu X, Xing X, Freeman G, Brown M, Liu XS. Abstract A12: Identification of resistance to immune checkpoint blockade Cancer Immunology Research. 6. DOI: 10.1158/2326-6074.Tumimm17-A12 |
0.764 |
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| 2018 |
Fu X, Pereira R, Angelis CD, Veeraraghavan J, Shea M, Nanda S, Feng Q, Jeselsohn R, O'Malley B, Brown M, Osborne C, Schiff R. Abstract P4-04-03: Hyperactive FOXA1 activates super-enhancer-engaged HIF2α/EPAS1 to promote endocrine-resistant metastatic ER-positive breast cancer Cancer Research. 78. DOI: 10.1158/1538-7445.Sabcs17-P4-04-03 |
0.685 |
|
| 2018 |
McNair C, Xu K, Mandigo AC, Benelli M, Leiby B, Rodrigues D, Lindberg J, Gronberg H, Laere BD, Dirix L, Visakorpi T, Li F, Feng FY, Bono Jd, Demichelis F, ... ... Brown M, et al. Abstract IA03: Differential impact of RB pathway status on E2F1 reprogramming and disease progression in human prostate cancer Cancer Research. 78. DOI: 10.1158/1538-7445.Prca2017-Ia03 |
0.447 |
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| 2018 |
McNair C, Xu K, Mandigo AC, Benelli M, Leiby B, Rodrigues D, Lindberg J, Gronberg H, Crespo M, Laere BD, Dirix L, Visakorpi T, Li F, Feng FY, Bono Jd, ... ... Brown M, et al. Abstract B040: Differential impact of RB status on E2F1 reprogramming in human cancer Cancer Research. 78. DOI: 10.1158/1538-7445.Prca2017-B040 |
0.427 |
|
| 2018 |
Kensler KH, Regan MM, Heng YJ, Pyle ME, Schnitt SJ, Thürlimann B, Viale G, Colleoni M, Brown M, Tamimi RM. Abstract 4207: Androgen receptor expression and ER+ breast cancer prognosis in the BIG 1-98 trial Cancer Research. 78: 4207-4207. DOI: 10.1158/1538-7445.Am2018-4207 |
0.467 |
|
| 2018 |
Lee I, Brown M. Abstract 3731: Deciphering the transcriptional role of estrogen receptor alpha in ovarian cancer Endocrinology. DOI: 10.1158/1538-7445.Am2018-3731 |
0.402 |
|
| 2017 |
Willis S, Sun Y, Abramovitz M, Fei T, Young B, Lin X, Ni M, Achua J, Regan MM, Gray KP, Gray R, Wang V, Long B, Kammler R, Sparano JA, ... ... Brown M, et al. High Expression of FGD3, a Putative Regulator of Cell Morphology and Motility, Is Prognostic of Favorable Outcome in Multiple Cancers. Jco Precision Oncology. 1. PMID 32913979 DOI: 10.1200/PO.17.00009 |
0.309 |
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| 2017 |
Wu Y, Zhang Z, Cenciarini ME, Proietti CJ, Amasino MF, Hong T, Yang M, Liao Y, Chiang HC, Kaklamani V, Jeselsohn R, Vadlamudi RK, Huang TH, Li R, De Angelis C, ... ... Brown M, et al. Tamoxifen resistance in breast cancer is regulated by the EZH2-ERα-GREB1 transcriptional axis. Cancer Research. PMID 29212856 DOI: 10.1158/0008-5472.Can-17-1327 |
0.727 |
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| 2017 |
McNair C, Xu K, Mandigo AC, Benelli M, Leiby B, Rodrigues D, Lindberg J, Gronberg H, Crespo M, De Laere B, Dirix L, Visakorpi T, Li F, Feng FY, de Bono J, ... ... Brown M, et al. Differential impact of RB status on E2F1 reprogramming in human cancer. The Journal of Clinical Investigation. PMID 29202480 DOI: 10.1172/Jci93566 |
0.407 |
|
| 2017 |
Mei S, Meyer CA, Zheng R, Qin Q, Wu Q, Jiang P, Li B, Shi X, Wang B, Fan J, Shih C, Brown M, Zang C, Liu XS. Cistrome Cancer: A Web Resource for Integrative Gene Regulation Modeling in Cancer. Cancer Research. 77: e19-e22. PMID 29092931 DOI: 10.1158/0008-5472.Can-17-0327 |
0.456 |
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| 2017 |
Cheng J, Park DE, Berrios C, White EA, Arora R, Yoon R, Branigan T, Xiao T, Westerling T, Federation A, Zeid R, Strober B, Swanson SK, Florens L, Bradner JE, ... Brown M, et al. Merkel cell polyomavirus recruits MYCL to the EP400 complex to promote oncogenesis. Plos Pathogens. 13: e1006668. PMID 29028833 DOI: 10.1371/Journal.Ppat.1006668 |
0.603 |
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| 2017 |
Labbé DP, Sweeney CJ, Brown M, Galbo P, Rosario S, Wadosky KM, Ku SY, Sjöström M, Alshalalfa M, Erho N, Davicioni E, Karnes RJ, Schaeffer EM, Jenkins RB, Den RB, et al. TOP2A and EZH2 provide early detection of an aggressive prostate cancer subgroup. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 28899973 DOI: 10.1158/1078-0432.Ccr-17-0413 |
0.706 |
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| 2017 |
Cato L, Neeb A, Sharp A, Buzón V, Ficarro SB, Yang L, Muhle-Goll C, Kuznik NC, Riisnaes R, Nava Rodrigues D, Armant O, Gourain V, Adelmant G, Ntim EA, Westerling T, ... ... Brown M, et al. Development of Bag-1L as a therapeutic target in androgen receptor-dependent prostate cancer. Elife. 6. PMID 28826504 DOI: 10.7554/Elife.27159 |
0.759 |
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| 2017 |
Dreijerink KMA, Timmers M, Brown M. Twenty years of menin: emerging opportunities for restoration of transcription in MEN1. Endocrine-Related Cancer. PMID 28811299 DOI: 10.1530/Erc-17-0281 |
0.384 |
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| 2017 |
Ebot EM, Gerke T, Labbé DP, Sinnott JA, Zadra G, Rider JR, Tyekucheva S, Wilson KM, Kelly RS, Shui IM, Loda M, Kantoff PW, Finn S, Vander Heiden MG, Brown M, et al. Gene expression profiling of prostate tissue identifies chromatin regulation as a potential link between obesity and lethal prostate cancer. Cancer. PMID 28700821 DOI: 10.1002/Cncr.30831 |
0.704 |
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| 2017 |
Fei T, Chen Y, Xiao T, Li W, Cato L, Zhang P, Cotter MB, Bowden M, Lis RT, Zhao SG, Wu Q, Feng FY, Loda M, He HH, Liu XS, ... Brown M, et al. Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing. Proceedings of the National Academy of Sciences of the United States of America. PMID 28611215 DOI: 10.1073/Pnas.1617467114 |
0.763 |
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| 2017 |
Jeselsohn R, Cornwell M, Pun M, Buchwalter G, Nguyen M, Bango C, Huang Y, Kuang Y, Paweletz C, Fu X, Nardone A, De Angelis C, Detre S, Dodson A, Mohammed H, ... ... Brown M, et al. Embryonic transcription factor SOX9 drives breast cancer endocrine resistance. Proceedings of the National Academy of Sciences of the United States of America. PMID 28507152 DOI: 10.1073/Pnas.1620993114 |
0.775 |
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| 2017 |
Jeselsohn R, De Angelis C, Brown M, Schiff R. The Evolving Role of the Estrogen Receptor Mutations in Endocrine Therapy-Resistant Breast Cancer. Current Oncology Reports. 19: 35. PMID 28374222 DOI: 10.1007/S11912-017-0591-8 |
0.644 |
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| 2017 |
Groner AC, Brown M. Role of steroid receptor and coregulator mutations in hormone-dependent cancers. The Journal of Clinical Investigation. 127: 1126-1135. PMID 28368289 DOI: 10.1172/Jci88885 |
0.804 |
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| 2017 |
Liu Y, Chen S, Wang S, Soares F, Fischer M, Meng F, Du Z, Lin C, Meyer C, DeCaprio JA, Brown M, Liu XS, He HH. Transcriptional landscape of the human cell cycle. Proceedings of the National Academy of Sciences of the United States of America. PMID 28289232 DOI: 10.1073/Pnas.1617636114 |
0.792 |
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| 2017 |
Dreijerink KM, Groner AC, Vos ES, Font-Tello A, Gu L, Chi D, Reyes J, Cook J, Lim E, Lin CY, de Laat W, Rao PK, Long HW, Brown M. Enhancer-Mediated Oncogenic Function of the Menin Tumor Suppressor in Breast Cancer. Cell Reports. 18: 2359-2372. PMID 28273452 DOI: 10.1016/J.Celrep.2017.02.025 |
0.834 |
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| 2017 |
Tavera-Mendoza LE, Westerling T, Libby E, Marusyk A, Cato L, Cassani R, Cameron LA, Ficarro SB, Marto JA, Klawitter J, Brown M. Vitamin D receptor regulates autophagy in the normal mammary gland and in luminal breast cancer cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 28242709 DOI: 10.1073/Pnas.1615015114 |
0.753 |
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| 2017 |
Ku SY, Rosario S, Wang Y, Mu P, Seshadri M, Goodrich ZW, Goodrich MM, Labbé DP, Gomez EC, Wang J, Long HW, Xu B, Brown M, Loda M, Sawyers CL, et al. Rb1 and Trp53 cooperate to suppress prostate cancer lineage plasticity, metastasis, and antiandrogen resistance. Science (New York, N.Y.). 355: 78-83. PMID 28059767 DOI: 10.1126/Science.Aah4199 |
0.729 |
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| 2017 |
Cato L, Neeb A, Sharp A, Buzón V, Ficarro SB, Yang L, Muhle-Goll C, Kuznik NC, Riisnaes R, Rodrigues DN, Armant O, Gourain V, Adelmant G, Ntim EA, Westerling T, ... ... Brown M, et al. Author response: Development of Bag-1L as a therapeutic target in androgen receptor-dependent prostate cancer Elife. DOI: 10.7554/Elife.27159.041 |
0.77 |
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| 2017 |
Xiao T, Li W, Wang X, Xu H, Wu Q, Jiang P, Yang J, Fei T, Zang C, Liao Q, Rennhack J, Andrechek E, Li N, Jeselsohn R, Liu SX, ... Brown M, et al. Abstract PR06: CRISPR screens identified drivers of endocrine resistance and synthetic lethal vulnerabilities in breast cancer Molecular Cancer Therapeutics. 16. DOI: 10.1158/1538-8514.Synthleth-Pr06 |
0.705 |
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| 2017 |
Ligibel J, Irwin M, Dillon D, Barry W, Giobbie-Hurder A, Frank E, Winer E, McTiernan A, Cornwell M, Pun M, Brown M, Jeselsohn R. Abstract S5-05: Impact of pre-operative exercise on breast cancer gene expression Cancer Research. 77. DOI: 10.1158/1538-7445.Sabcs16-S5-05 |
0.641 |
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| 2017 |
Fu X, Pereira R, Zhao D, Jung S, Jeselsohn R, Creighton C, Shea M, Nardone A, Angelis C, Tsimelzon A, Wang T, Gutierrez C, Huang S, Edwards D, Rimawi M, ... ... Brown M, et al. Abstract PD2-04: FOXA1 induces a pro-metastatic secretome through ER-dependent and independent transcriptional reprogramming in endocrine-resistant breast cancer Cancer Research. 77. DOI: 10.1158/1538-7445.Sabcs16-Pd2-04 |
0.676 |
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| 2017 |
Kensler KH, Poole EM, Collins LC, Beck AH, Rosner BA, Eliassen AH, Hankinson SE, Brown M, Tamimi RM. Abstract A05: Androgen receptor expression and breast cancer survival in the Nurses' Health Study cohorts Cancer Research. 77. DOI: 10.1158/1538-7445.Newfront17-A05 |
0.475 |
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| 2017 |
Singhal H, Chi D, Lim E, He H, Vadhi R, Rao PK, Long HW, Richardson AL, Garber J, Brown M. Abstract LB-257: Estrogen signaling in mature luminal and luminal progenitor cells of BRCA2 carriers and non-carriers Cancer Research. 77. DOI: 10.1158/1538-7445.Am2017-Lb-257 |
0.668 |
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| 2017 |
McNair C, Xu K, Mandigo A, Benelli M, Leiby B, Rodrigues D, Lindberg J, Gronberg H, Visakorpi T, Li F, Bono JD, Demichelis F, Rubin M, Brown M, Knudsen KE. Abstract LB-085: RB loss-induced genome wide E2F1 reprogramming drive advanced prostate cancer Cancer Research. 77. DOI: 10.1158/1538-7445.Am2017-Lb-085 |
0.384 |
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| 2017 |
Kuang Y, Siddiqui B, Hu J, Barry WT, Lin NU, Wagle N, Kirschmeier P, Jänne PA, Paweletz C, Krop I, Winer EP, Brown M, Jeselsohn R. Abstract 4950: The emergence of ESR1 mutations is associated with aromatase inhibitor and fulvestrant therapy Cancer Research. 77: 4950-4950. DOI: 10.1158/1538-7445.Am2017-4950 |
0.613 |
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| 2017 |
Kensler KH, Eliassen AH, Rosner BA, Hankinson SE, Brown M, Tamimi RM. Abstract 2257: Pre-diagnostic sex hormone levels and breast cancer survival in the Nurses' Health Study Epidemiology. 77: 2257-2257. DOI: 10.1158/1538-7445.Am2017-2257 |
0.333 |
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| 2017 |
Ku S, Rosario S, Wang Y, Mu P, Seshadri M, Goodrich Z, Goodrich M, Labbé DP, Gomez EC, Wang J, Long HW, Xu B, Brown M, Loda M, Sawyers CL, et al. Abstract 2170:Rb1suppresses prostate cancer metastasis and lineage plasticity underlying castration resistance Cancer Research. 77: 2170-2170. DOI: 10.1158/1538-7445.Am2017-2170 |
0.391 |
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| 2016 |
Zhu S, Li W, Liu J, Chen CH, Liao Q, Xu P, Xu H, Xiao T, Cao Z, Peng J, Yuan P, Brown M, Liu XS, Wei W. Genome-scale deletion screening of human long non-coding RNAs using a paired-guide RNA CRISPR-Cas9 library. Nature Biotechnology. PMID 27798563 DOI: 10.1038/Nbt.3715 |
0.727 |
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| 2016 |
Fu X, Jeselsohn R, Pereira R, Hollingsworth EF, Creighton CJ, Li F, Shea M, Nardone A, De Angelis C, Heiser LM, Anur P, Wang N, Grasso CS, Spellman PT, Griffith OL, ... ... Brown M, et al. FOXA1 overexpression mediates endocrine resistance by altering the ER transcriptome and IL-8 expression in ER-positive breast cancer. Proceedings of the National Academy of Sciences of the United States of America. 113: E6600-E6609. PMID 27791031 DOI: 10.1073/Pnas.1612835113 |
0.699 |
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| 2016 |
Mei S, Qin Q, Wu Q, Sun H, Zheng R, Zang C, Zhu M, Wu J, Shi X, Taing L, Liu T, Brown M, Meyer CA, Liu XS. Cistrome Data Browser: a data portal for ChIP-Seq and chromatin accessibility data in human and mouse. Nucleic Acids Research. PMID 27789702 DOI: 10.1093/Nar/Gkw983 |
0.742 |
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| 2016 |
Qin Q, Mei S, Wu Q, Sun H, Li L, Taing L, Chen S, Li F, Liu T, Zang C, Xu H, Chen Y, Meyer CA, Zhang Y, Brown M, et al. ChiLin: a comprehensive ChIP-seq and DNase-seq quality control and analysis pipeline. Bmc Bioinformatics. 17: 404. PMID 27716038 DOI: 10.1186/S12859-016-1274-4 |
0.71 |
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| 2016 |
Elias KM, Emori MM, Westerling T, Long H, Budina-Kolomets A, Li F, MacDuffie E, Davis MR, Holman A, Lawney B, Freedman ML, Quackenbush J, Brown M, Drapkin R. Epigenetic remodeling regulates transcriptional changes between ovarian cancer and benign precursors. Jci Insight. 1. PMID 27617304 DOI: 10.1172/Jci.Insight.87988 |
0.651 |
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| 2016 |
Groner AC, Brown M, Theurillat JP. Targeting Transcriptional Co-Activators in Advanced Prostate Cancer. Cell Cycle (Georgetown, Tex.). 0. PMID 27610751 DOI: 10.1080/15384101.2016.1229019 |
0.774 |
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| 2016 |
Townsend EC, Murakami MA, Christodoulou A, Christie AL, Köster J, DeSouza TA, Morgan EA, Kallgren SP, Liu H, Wu SC, Plana O, Montero J, Stevenson KE, Rao P, Vadhi R, ... ... Brown M, et al. The Public Repository of Xenografts Enables Discovery and Randomized Phase II-like Trials in Mice. Cancer Cell. 30: 183. PMID 27479034 DOI: 10.1016/J.Ccell.2016.06.008 |
0.598 |
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| 2016 |
Wang S, Zang C, Xiao T, Fan J, Mei S, Qin Q, Wu Q, Li XL, Xu K, He HH, Brown M, Meyer CA, Liu XS. Modeling cis-regulation with a compendium of genome-wide histone H3K27ac profiles. Genome Research. PMID 27466232 DOI: 10.1101/Gr.201574.115 |
0.422 |
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| 2016 |
Zhang H, Qi J, Reyes JM, Li L, Rao PK, Li F, Lin CY, Perry JA, Lawlor MA, Federation A, De Raedt T, Li YY, Liu Y, Duarte MA, Zhang Y, ... ... Brown M, et al. Oncogenic deregulation of EZH2 as an opportunity for targeted therapy in lung cancer. Cancer Discovery. PMID 27312177 DOI: 10.1158/2159-8290.Cd-16-0164 |
0.373 |
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| 2016 |
Spangle JM, Dreijerink KM, Groner AC, Cheng H, Ohlson CE, Reyes J, Lin CY, Bradner J, Zhao JJ, Roberts TM, Brown M. PI3K/AKT Signaling Regulates H3K4 Methylation in Breast Cancer. Cell Reports. PMID 27292631 DOI: 10.1016/J.Celrep.2016.05.046 |
0.785 |
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| 2016 |
Groner AC, Cato L, de Tribolet-Hardy J, Bernasocchi T, Janouskova H, Melchers D, Houtman R, Cato AC, Tschopp P, Gu L, Corsinotti A, Zhong Q, Fankhauser C, Fritz C, Poyet C, ... ... Brown M, et al. TRIM24 Is an Oncogenic Transcriptional Activator in Prostate Cancer. Cancer Cell. PMID 27238081 DOI: 10.1016/J.Ccell.2016.04.012 |
0.828 |
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| 2016 |
Jeselsohn R, Barry WT, Migliaccio I, Biagioni C, Zhao J, de Tribolet-Hardy J, Guarducci C, Bonechi M, Laing N, Winer EP, Brown M, Di Leo A, Malorni L. TransCONFIRM: Identification of a genetic signature of response to fulvestrant in advanced hormone receptor positive breast cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 27185372 DOI: 10.1158/1078-0432.Ccr-16-0148 |
0.69 |
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| 2016 |
Mounir Z, Korn JM, Westerling T, Lin F, Kirby CA, Schirle M, McAllister G, Hoffman G, Ramadan N, Hartung A, Feng Y, Kipp DR, Quinn C, Fodor M, Baird J, ... ... Brown M, et al. ERG signaling in prostate cancer is driven through PRMT5-dependent methylation of the androgen receptor. Elife. 5. PMID 27183006 DOI: 10.7554/Elife.13964 |
0.626 |
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| 2016 |
Cejas P, Li L, O'Neill NK, Duarte M, Rao P, Bowden M, Zhou CW, Mendiola M, Burgos E, Feliu J, Moreno-Rubio J, Guadalajara H, Moreno V, García-Olmo D, Bellmunt J, ... ... Brown M, et al. Chromatin immunoprecipitation from fixed clinical tissues reveals tumor-specific enhancer profiles. Nature Medicine. PMID 27111282 DOI: 10.1038/Nm.4085 |
0.322 |
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| 2016 |
Zang C, Wang T, Deng K, Li B, Hu S, Qin Q, Xiao T, Zhang S, Meyer CA, He HH, Brown M, Liu JS, Xie Y, Liu XS. High-dimensional genomic data bias correction and data integration using MANCIE. Nature Communications. 7: 11305. PMID 27072482 DOI: 10.1038/Ncomms11305 |
0.343 |
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| 2016 |
Townsend EC, Murakami MA, Christodoulou A, Christie AL, Köster J, DeSouza TA, Morgan EA, Kallgren SP, Liu H, Wu SC, Plana O, Montero J, Stevenson KE, Rao P, Vadhi R, ... ... Brown M, et al. The Public Repository of Xenografts Enables Discovery and Randomized Phase II-like Trials in Mice. Cancer Cell. 29: 574-86. PMID 27070704 DOI: 10.1016/J.Ccell.2016.03.008 |
0.631 |
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| 2016 |
Jeselsohn R, Brown M. How drug resistance takes shape. Elife. 5. PMID 27010172 DOI: 10.7554/Elife.14973 |
0.616 |
|
| 2016 |
Tavera-Mendoza LE, Brown M. A less invasive method for orthotopic injection of breast cancer cells into the mouse mammary gland. Laboratory Animals. PMID 26994106 DOI: 10.1177/0023677216640706 |
0.418 |
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| 2016 |
Du Z, Sun T, Hacisuleyman E, Fei T, Wang X, Brown M, Rinn JL, Lee MG, Chen Y, Kantoff PW, Liu XS. Integrative analyses reveal a long noncoding RNA-mediated sponge regulatory network in prostate cancer. Nature Communications. 7: 10982. PMID 26975529 DOI: 10.1038/Ncomms10982 |
0.446 |
|
| 2016 |
Malorni L, Giuliano M, Migliaccio I, Wang T, Creighton CJ, Lupien M, Fu X, Hilsenbeck SG, Healy N, De Angelis C, Mazumdar A, Trivedi MV, Massarweh S, Gutierrez C, De Placido S, ... ... Brown M, et al. Blockade of AP-1 Potentiates Endocrine Therapy and Overcomes Resistance. Molecular Cancer Research : McR. PMID 26965145 DOI: 10.1158/1541-7786.Mcr-15-0423 |
0.765 |
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| 2016 |
Liu Y, Fei T, Zheng X, Brown M, Zhang P, Liu XS, Wang H. An Integrative Pharmacogenomic Approach Identifies Two-drug Combination Therapies for Personalized Cancer Medicine. Scientific Reports. 6: 22120. PMID 26916442 DOI: 10.1038/Srep22120 |
0.383 |
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| 2016 |
Shu S, Lin CY, He HH, Witwicki RM, Tabassum DP, Roberts JM, Janiszewska M, Jin Huh S, Liang Y, Ryan J, Doherty E, Mohammed H, Guo H, Stover DG, Ekram MB, ... ... Brown M, et al. Response and resistance to BET bromodomain inhibitors in triple-negative breast cancer. Nature. PMID 26735014 DOI: 10.1038/Nature16508 |
0.627 |
|
| 2016 |
Mounir Z, Korn JM, Westerling T, Lin F, Kirby CA, Schirle M, McAllister G, Hoffman G, Ramadan N, Hartung A, Feng Y, Kipp DR, Quinn C, Fodor M, Baird J, ... ... Brown M, et al. Author response: ERG signaling in prostate cancer is driven through PRMT5-dependent methylation of the Androgen Receptor Elife. DOI: 10.7554/Elife.13964.024 |
0.597 |
|
| 2016 |
Sewastianik T, Zhao J, Jiang M, Dennis PS, Brown M, Wong K, Carrasco RD. Overexpression of BCL9, a Wnt/β-Catenin Transcriptional Co-Activator, in Transgenic Mice Promotes Spontaneous Development of B-Cell Malignancies Blood. 128: 441-441. DOI: 10.1182/Blood.V128.22.441.441 |
0.346 |
|
| 2016 |
Elias KM, Emori M, Brown M, Drapkin R. Abstract A69: The PAX8 cistrome in benign and malignant Mullerian epithelia. Clinical Cancer Research. 22. DOI: 10.1158/1557-3265.Ovca15-A69 |
0.424 |
|
| 2016 |
Ebot EM, Gerke T, Tyekucheva S, Labbé DP, Zadra G, Kelly RS, Bowden M, Rider JR, Wilson MK, Martin NE, Brown M, Heiden MGV, Giovannucci EL, Loda M, Mucci LA. Abstract B67: Identifying obesity-linked gene expression changes in prostate cancer Molecular Cancer Research. 14. DOI: 10.1158/1557-3125.Metca15-B67 |
0.399 |
|
| 2016 |
Shu S, Lin C, He HH, Witwicki R, Roberts J, Tabassum D, Liang Y, Ekram M, Doherty E, Brown J, Mohammed H, D'Santos C, McKeown M, Ott C, Qi J, ... ... Brown M, et al. Abstract B16: Response and resistance to BET bromodomain inhibitors in triple-negative breast cancer Molecular Cancer Research. 14. DOI: 10.1158/1557-3125.Advbc15-B16 |
0.664 |
|
| 2016 |
Luo F, Le X, Jeselsohn R, Brown M, Garraway L. Abstract P3-05-13: Estrogen-independent growth ofESR1-mutant breast cancer cells requires CDK4/6 Cancer Research. 76. DOI: 10.1158/1538-7445.Sabcs15-P3-05-13 |
0.707 |
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| 2016 |
Nguyen M, Buchwalter G, Luo F, Garraway L, Brown M, Jeselsohn R. Abstract P3-05-09: Exploring bazedoxifene and palbociclib as potential therapeutic strategies for overcoming ESR1-mediated endocrine resistance Cancer Research. 76. DOI: 10.1158/1538-7445.Sabcs15-P3-05-09 |
0.682 |
|
| 2016 |
Fei T, Chen Y, Brown M, Liu XS. Abstract IA11: Dependency of prostate cancer on HNRNPL and its associated RNAs Cancer Research. 76. DOI: 10.1158/1538-7445.Nonrna15-Ia11 |
0.372 |
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| 2016 |
Fei T, Chen Y, Liu XS, Brown M. Abstract A22: Functional long noncoding RNAs in castration-resistant prostate cancer Cancer Research. 76. DOI: 10.1158/1538-7445.Nonrna15-A22 |
0.793 |
|
| 2016 |
Zang C, Wang T, Deng K, Li B, Hu S, Qin Q, Xiao T, Zhang S, Meyer CA, He HH, Brown M, Liu JS, Xie Y, Liu XS. Abstract B24: High-dimensional genomic data integration and bias correction using MANCIE Cancer Research. 76. DOI: 10.1158/1538-7445.Chromepi15-B24 |
0.745 |
|
| 2016 |
Labbé DP, Zadra G, Ebot EM, Lin CY, Reyes JM, Cacciatore S, Cotter M, Creech AL, Jaffe JD, Kantoff PW, Bradner JE, Mucci LA, Loda M, Brown M. Abstract A10: High-fat diet enhances MYC-driven prostate cancer through epigenomic and metabolomic rewiring Cancer Research. 76. DOI: 10.1158/1538-7445.Chromepi15-A10 |
0.399 |
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| 2016 |
Cato L, Neeb A, Sharp A, Ficarro S, Buzon V, Salvatella X, Marto JA, Bono JSd, Cato AC, Brown M. Abstract 864: Androgen receptor stability in prostate cancer is regulated by the cochaperone Bag-1L Endocrinology. 76: 864-864. DOI: 10.1158/1538-7445.Am2016-864 |
0.771 |
|
| 2016 |
Kensler K, Beck A, Beca F, Collins L, Schnitt S, Hazra A, Hankinson S, Brown M, Tamimi R. Abstract 4295: Androgen receptor expression in normal breast TDLUs and subsequent breast cancer risk Cancer Research. 76: 4295-4295. DOI: 10.1158/1538-7445.Am2016-4295 |
0.451 |
|
| 2016 |
Labbe DP, Zadra G, Yang M, Lin CY, Reyes JM, Cacciatore S, Ebot EM, Cotter MB, Creech AL, Jaffe JD, Kantoff PW, Bradner JE, Mucci LA, Chavarro JE, Loda M, ... Brown M, et al. Abstract 2674: High fat diet accelerates MYC-driven prostate cancer through metabolic and epigenomic rewiring Cancer Research. 76: 2674-2674. DOI: 10.1158/1538-7445.Am2016-2674 |
0.412 |
|
| 2016 |
Groner AC, Cato L, Tribolet-Hardy Jd, Bernasocchi T, Zhong Q, Fankhauser C, Fritz C, Poyet C, Wagner U, Garraway LA, Wild PJ, Theurillat J, Brown M. Abstract 1806: TRIM24 is an oncogenic transcriptional activator in prostate cancer Cancer Research. 76: 1806-1806. DOI: 10.1158/1538-7445.Am2016-1806 |
0.836 |
|
| 2015 |
Xu H, Xu K, He HH, Zang C, Chen CH, Chen Y, Qin Q, Wang S, Wang C, Hu S, Li F, Long H, Brown M, Liu XS. Integrative analysis reveals the transcriptional collaboration between EZH2 and E2F1 in the regulation of cancer-related gene expression. Molecular Cancer Research : McR. PMID 26659825 DOI: 10.1158/1541-7786.Mcr-15-0313 |
0.51 |
|
| 2015 |
Pomerantz MM, Li F, Takeda DY, Lenci R, Chonkar A, Chabot M, Cejas P, Vazquez F, Cook J, Shivdasani RA, Bowden M, Lis R, Hahn WC, Kantoff PW, Brown M, et al. The androgen receptor cistrome is extensively reprogrammed in human prostate tumorigenesis. Nature Genetics. PMID 26457646 DOI: 10.1038/Ng.3419 |
0.415 |
|
| 2015 |
Wang J, Zhang X, Beck AH, Collins LC, Chen WY, Tamimi RM, Hazra A, Brown M, Rosner B, Hankinson SE. Alcohol Consumption and Risk of Breast Cancer by Tumor Receptor Expression. Hormones & Cancer. PMID 26385458 DOI: 10.1007/S12672-015-0235-0 |
0.415 |
|
| 2015 |
Jeselsohn R, Buchwalter G, Angelis C, Brown M, Schiff R. ESR1 mutations-a mechanism for acquired endocrine resistance in breast cancer. Nature Reviews. Clinical Oncology. PMID 26122181 DOI: 10.1038/Nrclinonc.2015.117 |
0.655 |
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| 2015 |
Zhang X, Eliassen AH, Tamimi RM, Hazra A, Beck AH, Brown M, Collins LC, Rosner B, Hankinson SE. Adult body size and physical activity in relation to risk of breast cancer according to tumor androgen receptor status. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 24: 962-8. PMID 25855627 DOI: 10.1158/1055-9965.EPI-14-1429 |
0.302 |
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| 2015 |
Hsieh CL, Botta G, Gao S, Li T, Van Allen EM, Treacy DJ, Cai C, He HH, Sweeney CJ, Brown M, Balk SP, Nelson PS, Garraway LA, Kantoff PW. PLZF, a Tumor Suppressor Genetically Lost in Metastatic Castration-Resistant Prostate Cancer, Is a Mediator of Resistance to Androgen Deprivation Therapy. Cancer Research. 75: 1944-8. PMID 25808865 DOI: 10.1158/0008-5472.Can-14-3602 |
0.638 |
|
| 2015 |
Brown M, Chinnaiyan A, Farsetti A, Livingston DM, Loda M, Schuele R, Mihich E. 26th Pezcoller symposium: cancers driven by hormones. Cancer Research. 75: 1177-80. PMID 25788695 DOI: 10.1158/0008-5472.Can-14-2902 |
0.644 |
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| 2015 |
Chia K, O'Brien M, Brown M, Lim E. Targeting the androgen receptor in breast cancer. Current Oncology Reports. 17: 4. PMID 25665553 DOI: 10.1007/S11912-014-0427-8 |
0.462 |
|
| 2015 |
Bailey ST, Westerling T, Brown M. Loss of estrogen-regulated microRNA expression increases HER2 signaling and is prognostic of poor outcome in luminal breast cancer. Cancer Research. 75: 436-45. PMID 25388283 DOI: 10.1158/0008-5472.Can-14-1041 |
0.396 |
|
| 2015 |
van Kruchten M, de Vries EG, Glaudemans AW, van Lanschot MC, van Faassen M, Kema IP, Brown M, Schröder CP, de Vries EF, Hospers GA. Measuring residual estrogen receptor availability during fulvestrant therapy in patients with metastatic breast cancer. Cancer Discovery. 5: 72-81. PMID 25380844 DOI: 10.1158/2159-8290.Cd-14-0697 |
0.369 |
|
| 2015 |
Mounir Z, Lin F, Lin VG, Korn JM, Yu Y, Valdez R, Aina OH, Buchwalter G, Jaffe AB, Korpal M, Zhu P, Brown M, Cardiff RD, Rocnik JL, Yang Y, et al. TMPRSS2:ERG blocks neuroendocrine and luminal cell differentiation to maintain prostate cancer proliferation. Oncogene. 34: 3815-25. PMID 25263440 DOI: 10.1038/Onc.2014.308 |
0.457 |
|
| 2015 |
Sun T, Du Z, Fei T, Brown M, Lee GM, Chen Y, Liu XS, Kantoff PW. Long non-coding RNA-mediated PTEN regulation in prostate cancer. Journal of Clinical Oncology. 33: e16081-e16081. DOI: 10.1200/Jco.2015.33.15_Suppl.E16081 |
0.789 |
|
| 2015 |
Jeselsohn RM, Barry WT, Zhao J, Buchwalter G, Guarducci C, Migliaccio I, Biagioni C, Bonechi M, Laing N, Rukazenkov Y, Winer EP, Brown M, Leo AD, Malorni L. Abstract S1-01: TransCONFIRM: The correlative analysis of breast tumors from patients with advanced hormone receptor positive disease identifies a genetic signature associated with decreased benefit from single agent fulvestrant Cancer Research. 75. DOI: 10.1158/1538-7445.Sabcs14-S1-01 |
0.682 |
|
| 2015 |
Fu X, Jeselsohn R, Hollingsworth EF, Lopez-Terrada D, Creighton CJ, Nardone A, Shea M, Heiser LM, Anur P, Wang N, Grasso C, Spellman P, Gutierrez C, Rimawi MF, Hilsenbeck SG, ... ... Brown M, et al. Abstract PD6-2: FoxA1 gene amplification in ER+ breast cancer mediates endocrine resistance by increasing IL-8 Cancer Research. 75. DOI: 10.1158/1538-7445.Sabcs14-Pd6-2 |
0.682 |
|
| 2015 |
Cao SA, Lim E, Brown M, Bailey ST. Abstract P3-05-14: Modeling chemoendocrine therapy for ER+/p53wt luminal breast cancer Cancer Research. 75. DOI: 10.1158/1538-7445.Sabcs14-P3-05-14 |
0.453 |
|
| 2015 |
Bailey ST, Westerling T, Brown M. Abstract LB-016: Estrogen receptor stability is modulated by calpain activity in breast cancer cells Cancer Research. 75. DOI: 10.1158/1538-7445.Am2015-Lb-016 |
0.44 |
|
| 2015 |
Gao S, Gao Y, He H, Brown M, Balk S, Cai C. Abstract 966: LSD1 functions as a global androgen receptor coactivator and is a therapeutic target in prostate cancer Cancer Research. 75: 966-966. DOI: 10.1158/1538-7445.Am2015-966 |
0.506 |
|
| 2015 |
Ebot EM, Gerke T, Tyekucheva S, Labbé DP, Zadra G, Kelly RS, Bowden M, Rider JR, Wilson KM, Martin NE, Brown M, Heiden MGV, Giovannucci EL, Loda M, Mucci LA. Abstract 4686: Identifying obesity-linked gene expression changes in prostate cancer Cancer Research. 75: 4686-4686. DOI: 10.1158/1538-7445.Am2015-4686 |
0.377 |
|
| 2015 |
Cato L, Neeb A, Adelmant G, Ficarro S, Westerling T, Marto JA, Cato AC, Brown M. Abstract 4677: Control of androgen receptor function by the genomic action of the cochaperone Bag-1L Cancer Research. 75: 4677-4677. DOI: 10.1158/1538-7445.Am2015-4677 |
0.778 |
|
| 2015 |
Groner AC, Tribolet-Hardy Jd, Theurillat J, Wild PJ, Brown M. Abstract 1865: TRIM24 acts as a transcriptional co-activator of the androgen receptor during prostate cancer progression Endocrinology. 75: 1865-1865. DOI: 10.1158/1538-7445.Am2015-1865 |
0.784 |
|
| 2015 |
Elias KM, Emori M, Westerling T, Long H, Li F, Macduffie E, Holman A, Lawney B, Quackenbush J, Brown M, Drapkin R. PAX8 and lineage dependence in high grade serous ovarian cancer Gynecologic Oncology. 139: 591-592. DOI: 10.1016/J.Ygyno.2015.09.044 |
0.354 |
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| 2014 |
Labbé DP, Zadra G, Ebot EM, Mucci LA, Kantoff PW, Loda M, Brown M. Role of diet in prostate cancer: the epigenetic link. Oncogene. PMID 25531313 DOI: 10.1038/Onc.2014.422 |
0.34 |
|
| 2014 |
Cai C, He HH, Gao S, Chen S, Yu Z, Gao Y, Chen S, Chen MW, Zhang J, Ahmed M, Wang Y, Metzger E, Schüle R, Liu XS, Brown M, et al. Lysine-specific demethylase 1 has dual functions as a major regulator of androgen receptor transcriptional activity. Cell Reports. 9: 1618-27. PMID 25482560 DOI: 10.1016/J.Celrep.2014.11.008 |
0.421 |
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| 2014 |
Li W, Xu H, Xiao T, Cong L, Love MI, Zhang F, Irizarry RA, Liu JS, Brown M, Liu XS. MAGeCK enables robust identification of essential genes from genome-scale CRISPR/Cas9 knockout screens. Genome Biology. 15: 554. PMID 25476604 DOI: 10.1186/S13059-014-0554-4 |
0.325 |
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| 2014 |
Cato L, Neeb A, Brown M, Cato AC. Control of steroid receptor dynamics and function by genomic actions of the cochaperones p23 and Bag-1L. Nuclear Receptor Signaling. 12: e005. PMID 25422595 DOI: 10.1621/Nrs.12005 |
0.754 |
|
| 2014 |
Hu Y, Petit SA, Ficarro SB, Toomire KJ, Xie A, Lim E, Cao SA, Park E, Eck MJ, Scully R, Brown M, Marto JA, Livingston DM. PARP1-driven poly-ADP-ribosylation regulates BRCA1 function in homologous recombination-mediated DNA repair. Cancer Discovery. 4: 1430-47. PMID 25252691 DOI: 10.1158/2159-8290.Cd-13-0891 |
0.724 |
|
| 2014 |
Gordon FK, Vallaster CS, Westerling T, Iyer LK, Brown M, Schnitzler GR. Research resource: Aorta- and liver-specific ERα-binding patterns and gene regulation by estrogen. Molecular Endocrinology (Baltimore, Md.). 28: 1337-51. PMID 24992180 DOI: 10.1210/Me.2013-1395 |
0.416 |
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| 2014 |
Yoo S, Pettersson A, Jordahl KM, Lis RT, Lindstrom S, Meisner A, Nuttall EJ, Stack EC, Stampfer MJ, Kraft P, Brown M, Loda M, Giovannucci EL, Kantoff PW, Mucci LA. Androgen receptor CAG repeat polymorphism and risk of TMPRSS2:ERG-positive prostate cancer. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 23: 2027-31. PMID 24925673 DOI: 10.1158/1055-9965.Epi-14-0020 |
0.45 |
|
| 2014 |
Lim E, Ni M, Cao S, Hazra A, Tamimi RM, Brown M. Importance of Breast Cancer Subtype in the Development of Androgen Receptor Directed Therapy. Current Breast Cancer Reports. 6: 71-78. PMID 24860642 DOI: 10.1007/S12609-014-0140-5 |
0.464 |
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| 2014 |
Hsieh CL, Fei T, Chen Y, Li T, Gao Y, Wang X, Sun T, Sweeney CJ, Lee GS, Chen S, Balk SP, Liu XS, Brown M, Kantoff PW. Enhancer RNAs participate in androgen receptor-driven looping that selectively enhances gene activation. Proceedings of the National Academy of Sciences of the United States of America. 111: 7319-24. PMID 24778216 DOI: 10.1073/Pnas.1324151111 |
0.775 |
|
| 2014 |
Chen X, Iliopoulos D, Zhang Q, Tang Q, Greenblatt MB, Hatziapostolou M, Lim E, Tam WL, Ni M, Chen Y, Mai J, Shen H, Hu DZ, Adoro S, Hu B, ... ... Brown M, et al. XBP1 promotes triple-negative breast cancer by controlling the HIF1α pathway. Nature. 508: 103-7. PMID 24670641 DOI: 10.1038/Nature13119 |
0.499 |
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| 2014 |
Jehle K, Cato L, Neeb A, Muhle-Goll C, Jung N, Smith EW, Buzon V, Carbó LR, Estébanez-Perpiñá E, Schmitz K, Fruk L, Luy B, Chen Y, Cox MB, Bräse S, ... Brown M, et al. Coregulator control of androgen receptor action by a novel nuclear receptor-binding motif. The Journal of Biological Chemistry. 289: 8839-51. PMID 24523409 DOI: 10.1074/Jbc.M113.534859 |
0.76 |
|
| 2014 |
Jeselsohn R, Yelensky R, Buchwalter G, Frampton G, Meric-Bernstam F, Gonzalez-Angulo AM, Ferrer-Lozano J, Perez-Fidalgo JA, Cristofanilli M, Gómez H, Arteaga CL, Giltnane J, Balko JM, Cronin MT, Jarosz M, ... ... Brown M, et al. Emergence of constitutively active estrogen receptor-α mutations in pretreated advanced estrogen receptor-positive breast cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 20: 1757-67. PMID 24398047 DOI: 10.1158/1078-0432.Ccr-13-2332 |
0.68 |
|
| 2014 |
Bailey ST, Miron PL, Choi YJ, Kochupurakkal B, Maulik G, Rodig SJ, Tian R, Foley KM, Bowman T, Miron A, Brown M, Iglehart JD, Biswas DK. NF-κB activation-induced anti-apoptosis renders HER2-positive cells drug resistant and accelerates tumor growth. Molecular Cancer Research : McR. 12: 408-20. PMID 24319068 DOI: 10.1158/1541-7786.Mcr-13-0206-T |
0.411 |
|
| 2014 |
Sun T, Wang X, He HH, Sweeney CJ, Liu SX, Brown M, Balk S, Lee GS, Kantoff PW. MiR-221 promotes the development of androgen independence in prostate cancer cells via downregulation of HECTD2 and RAB1A. Oncogene. 33: 2790-800. PMID 23770851 DOI: 10.1038/Onc.2013.230 |
0.375 |
|
| 2014 |
Kruchten Mv, Vries EGEd, Brown M, Glaudemans AWJM, Lanschot MCv, Kema IP, Faassen MV, Schroder CP, Vries EFJD, Hospers G. Residual estrogen receptor availability during fulvestrant 500 mg therapy in patients with metastatic breast cancer. Journal of Clinical Oncology. 32: 588-588. DOI: 10.1200/Jco.2014.32.15_Suppl.588 |
0.368 |
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| 2014 |
Pomerantz MM, Li F, Chonkar A, Vazquez F, Chabot M, Cejas P, Bowden M, Shivdasani R, Hahn WC, Brown M, Kantoff PW, Loda M, Long H, Freedman ML. Effect of HOXB13 and FOXA1 on the AR cistrome during prostate tumorigenesis in primary human tissue. Journal of Clinical Oncology. 32: 5018-5018. DOI: 10.1200/Jco.2014.32.15_Suppl.5018 |
0.387 |
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| 2014 |
Zhang X, Eliassen AH, Tamimi R, Hazra A, Beck AH, Brown M, Collins LC, Rosner B, Hankinson SE. Abstract LB-275: Adult body size and physical activity in relation to risk of breast cancer defined by tumor androgen receptor status Cancer Research. 74. DOI: 10.1158/1538-7445.Am2014-Lb-275 |
0.429 |
|
| 2014 |
Fei T, Chen Y, Du Z, Liu XS, Brown M. Abstract 5238: Integrative analysis of functional long noncoding RNAs during prostate cancer progression Cancer Research. 74: 5238-5238. DOI: 10.1158/1538-7445.Am2014-5238 |
0.789 |
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| 2014 |
Dreijerink K, Conemans E, Cornelissen C, Blokland MV, Mannstadt M, Pieterman C, Herder WD, Havekes B, Fliers E, Hermus A, Vriens M, Timmers M, Wall EVd, Brown M, Luijt RVd, et al. Abstract 1289: Breast cancer predisposition in multiple endocrine neoplasia type 1 Cancer Research. 74: 1289-1289. DOI: 10.1158/1538-7445.Am2014-1289 |
0.423 |
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| 2013 |
Pfefferle AD, Herschkowitz JI, Usary J, Harrell JC, Spike BT, Adams JR, Torres-Arzayus MI, Brown M, Egan SE, Wahl GM, Rosen JM, Perou CM. Transcriptomic classification of genetically engineered mouse models of breast cancer identifies human subtype counterparts. Genome Biology. 14: R125. PMID 24220145 DOI: 10.1186/Gb-2013-14-11-R125 |
0.394 |
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| 2013 |
Merenbakh-Lamin K, Ben-Baruch N, Yeheskel A, Dvir A, Soussan-Gutman L, Jeselsohn R, Yelensky R, Brown M, Miller VA, Sarid D, Rizel S, Klein B, Rubinek T, Wolf I. D538G mutation in estrogen receptor-α: A novel mechanism for acquired endocrine resistance in breast cancer. Cancer Research. 73: 6856-64. PMID 24217577 DOI: 10.1158/0008-5472.Can-13-1197 |
0.71 |
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| 2013 |
van Kruchten M, de Vries EGE, Brown M, de Vries EFJ, Glaudemans AWJM, Dierckx RAJO, Schröder CP, Hospers GAP. PET imaging of oestrogen receptors in patients with breast cancer. The Lancet. Oncology. 14: e465-e475. PMID 24079874 DOI: 10.1016/S1470-2045(13)70292-4 |
0.326 |
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| 2013 |
McLaughlin SK, Olsen SN, Dake B, De Raedt T, Lim E, Bronson RT, Beroukhim R, Polyak K, Brown M, Kuperwasser C, Cichowski K. The RasGAP gene, RASAL2, is a tumor and metastasis suppressor. Cancer Cell. 24: 365-78. PMID 24029233 DOI: 10.1016/J.Ccr.2013.08.004 |
0.389 |
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| 2013 |
Tam WL, Lu H, Buikhuisen J, Soh BS, Lim E, Reinhardt F, Wu ZJ, Krall JA, Bierie B, Guo W, Chen X, Liu XS, Brown M, Lim B, Weinberg RA. Protein kinase C α is a central signaling node and therapeutic target for breast cancer stem cells. Cancer Cell. 24: 347-64. PMID 24029232 DOI: 10.1016/J.Ccr.2013.08.005 |
0.765 |
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| 2013 |
Buchwalter G, Hickey MM, Cromer A, Selfors LM, Gunawardane RN, Frishman J, Jeselsohn R, Lim E, Chi D, Fu X, Schiff R, Brown M, Brugge JS. PDEF promotes luminal differentiation and acts as a survival factor for ER-positive breast cancer cells. Cancer Cell. 23: 753-67. PMID 23764000 DOI: 10.1016/J.Ccr.2013.04.026 |
0.789 |
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| 2013 |
Bhat-Nakshatri P, Song EK, Collins NR, Uversky VN, Dunker AK, O'Malley BW, Geistlinger TR, Carroll JS, Brown M, Nakshatri H. Interplay between estrogen receptor and AKT in estradiol-induced alternative splicing. Bmc Medical Genomics. 6: 21. PMID 23758675 DOI: 10.1186/1755-8794-6-21 |
0.576 |
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| 2013 |
Jeselsohn RM, Werner L, Regan MM, Fatima A, Gilmore L, Collins LC, Beck AH, Bailey ST, He HH, Buchwalter G, Brown M, Iglehart JD, Richardson A, Come SE. Digital quantification of gene expression in sequential breast cancer biopsies reveals activation of an immune response. Plos One. 8: e64225. PMID 23741308 DOI: 10.1371/Journal.Pone.0064225 |
0.682 |
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| 2013 |
Du Z, Fei T, Verhaak RG, Su Z, Zhang Y, Brown M, Chen Y, Liu XS. Integrative genomic analyses reveal clinically relevant long noncoding RNAs in human cancer. Nature Structural & Molecular Biology. 20: 908-13. PMID 23728290 DOI: 10.1038/Nsmb.2591 |
0.403 |
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| 2013 |
Ni M, Chen Y, Fei T, Li D, Lim E, Liu XS, Brown M. Amplitude modulation of androgen signaling by c-MYC. Genes & Development. 27: 734-48. PMID 23530127 DOI: 10.1101/Gad.209569.112 |
0.49 |
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| 2013 |
Sun H, Qin B, Liu T, Wang Q, Liu J, Wang J, Lin X, Yang Y, Taing L, Rao PK, Brown M, Zhang Y, Long HW, Liu XS. CistromeFinder for ChIP-seq and DNase-seq data reuse. Bioinformatics (Oxford, England). 29: 1352-4. PMID 23508969 DOI: 10.1093/Bioinformatics/Btt135 |
0.737 |
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| 2013 |
Cai C, Wang H, He HH, Chen S, He L, Ma F, Mucci L, Wang Q, Fiore C, Sowalsky AG, Loda M, Liu XS, Brown M, Balk SP, Yuan X. ERG induces androgen receptor-mediated regulation of SOX9 in prostate cancer. The Journal of Clinical Investigation. 123: 1109-22. PMID 23426182 DOI: 10.1172/Jci66666 |
0.473 |
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| 2013 |
Li Q, Seo JH, Stranger B, McKenna A, Pe'er I, Laframboise T, Brown M, Tyekucheva S, Freedman ML. Integrative eQTL-based analyses reveal the biology of breast cancer risk loci. Cell. 152: 633-41. PMID 23374354 DOI: 10.1016/J.Cell.2012.12.034 |
0.454 |
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| 2013 |
He HH, Meyer CA, Long H, Liu XS, Brown M. A closer look into DNase I hypersensitivity Epigenetics & Chromatin. 6. DOI: 10.1186/1756-8935-6-S1-P25 |
0.773 |
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| 2013 |
Groner AC, Brown M. The role of TRIM24 during prostate cancer progression Epigenetics & Chromatin. 6. DOI: 10.1186/1756-8935-6-S1-P24 |
0.743 |
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| 2013 |
Cato L, Jehle K, Neeb A, Cato AC, Brown M. Control of androgen receptor action by a novel nuclear receptor binding motif in Bag-1L Epigenetics & Chromatin. 6. DOI: 10.1186/1756-8935-6-S1-P13 |
0.772 |
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| 2013 |
Xu K, Wu ZJ, Groner AC, He HH, Cai C, Stack EC, Loda M, Liu T, Morrissey C, Vessella RL, Kantoff PW, Balk SP, Liu XS, Brown M. Polycomb-independent activity of EZH2 in castration resistant prostate cancer Epigenetics & Chromatin. 6. DOI: 10.1186/1756-8935-6-S1-O14 |
0.798 |
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| 2013 |
Brown M. Abstract IA15: Epigenetics of hormone dependence Cancer Research. 73. DOI: 10.1158/1538-7445.Cec13-Ia15 |
0.533 |
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| 2013 |
Cai C, He HH, Brown M, Balk SP. Abstract A46: LSD1 globally mediates epigenetic modifications on androgen receptor-dependent enhancers Cancer Research. 73. DOI: 10.1158/1538-7445.Cec13-A46 |
0.472 |
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| 2013 |
Tavera LE, Westerling T, Brown M. Abstract 3562: Genome-wide analysis of the vitamin D receptor (VDR) binding sites reveals vitamin D role modulating autophagy and metabolism in luminal-like breast cancer cells. Cancer Research. 73: 3562-3562. DOI: 10.1158/1538-7445.Am2013-3562 |
0.402 |
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| 2013 |
Chi D, He H, Yeung T, Jeselsohn R, Schnitt S, Garber J, Richardson A, Lim E, Brown M. Abstract 2313: Differences in estrogen receptor signaling in normal mammary epithelial cells and ER-positive primary breast tumors and metastases. Cancer Research. 73: 2313-2313. DOI: 10.1158/1538-7445.Am2013-2313 |
0.785 |
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| 2013 |
Jeselsohn R, Yelensky R, Buchwalter G, Frampton G, Meric-Bernstam F, Cristofanilli M, Arteaga C, Balko J, Gilmore L, Schnitt S, Come S, Pusztai L, Stephens P, Miller V, Brown M. Abstract S3-06: Emergence of constitutively active estrogen receptor mutations in advanced estrogen receptor positive breast cancer Cancer Research. 73. DOI: 10.1158/0008-5472.Sabcs13-S3-06 |
0.69 |
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| 2013 |
Lin N, Whitesell L, Gelman R, Mayer E, Krop I, Santagata S, Lowe A, Proia D, Farooq S, Brown M, Iannone M, Lindquist S, Winer E. Abstract OT3-2-05: Randomized phase II study of fulvestrant with or without ganetespib in patients (pts) with hormone receptor (HR)-positive metastatic breast cancer Cancer Research. 73. DOI: 10.1158/0008-5472.Sabcs13-Ot3-2-05 |
0.361 |
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| 2012 |
Xu K, Wu ZJ, Groner AC, He HH, Cai C, Lis RT, Wu X, Stack EC, Loda M, Liu T, Xu H, Cato L, Thornton JE, Gregory RI, Morrissey C, ... ... Brown M, et al. EZH2 oncogenic activity in castration-resistant prostate cancer cells is Polycomb-independent. Science (New York, N.Y.). 338: 1465-9. PMID 23239736 DOI: 10.1126/Science.1227604 |
0.84 |
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| 2012 |
Bailey ST, Shin H, Westerling T, Liu XS, Brown M. Estrogen receptor prevents p53-dependent apoptosis in breast cancer. Proceedings of the National Academy of Sciences of the United States of America. 109: 18060-5. PMID 23077249 DOI: 10.1073/Pnas.1018858109 |
0.787 |
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| 2012 |
Villa A, Della Torre S, Stell A, Cook J, Brown M, Maggi A. Tetradian oscillation of estrogen receptor α is necessary to prevent liver lipid deposition. Proceedings of the National Academy of Sciences of the United States of America. 109: 11806-11. PMID 22761311 DOI: 10.1073/Pnas.1205797109 |
0.308 |
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| 2012 |
He HH, Meyer CA, Chen MW, Jordan VC, Brown M, Liu XS. Differential DNase I hypersensitivity reveals factor-dependent chromatin dynamics. Genome Research. 22: 1015-25. PMID 22508765 DOI: 10.1101/Gr.133280.111 |
0.446 |
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| 2012 |
Lim E, Ni M, Hazra A, Tamimi R, Brown M. Elucidating the role of androgen receptor in breast cancer Clinical Investigation. 2: 1003-1011. DOI: 10.4155/Cli.12.88 |
0.458 |
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| 2012 |
Lim E, He HH, Chi D, Garber JE, Richardson A, Brown M. Estrogen receptor (ER) signaling in normal, BRCA (B) 1 and B2 mutation associated, and ER-positive breast cancer (BC) mammary cells. Journal of Clinical Oncology. 30: 576-576. DOI: 10.1200/Jco.2012.30.15_Suppl.576 |
0.623 |
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| 2012 |
Mounir Z, Pagliarini R, Lin F, Schirle M, Klekota J, Feng Y, Hartung A, Jaffe A, Buchwalter G, Brown M. Abstract B23: Identification of TMPRSS2:ERG-dependent regulators of AR function and differentiation status in prostate cancer Cancer Research. 72: B23-B23. DOI: 10.1158/1538-7445.Prca2012-B23 |
0.456 |
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| 2012 |
Bailey ST, Shin H, Liu XS, Brown M. Abstract LB-74: The estrogen receptor regulates the transcription of p53 target genes in breast cancer cells Cancer Research. 72. DOI: 10.1158/1538-7445.Am2012-Lb-74 |
0.484 |
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| 2012 |
Westerling T, Tavera-Mendoza L, Brown M. Abstract LB-406: Identification of functional enhancer SNPs in breast cancer models though ChIP-sequencing screening Cancer Research. 72. DOI: 10.1158/1538-7445.Am2012-Lb-406 |
0.425 |
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| 2012 |
Tavera LE, Westerling T, Brown M. Abstract LB-275: Genome-wide analysis of the vitamin D receptor (VDR) binding sites reveals vitamin D role mediating autophagy in luminal-like breast cancer cells Cancer Research. 72. DOI: 10.1158/1538-7445.Am2012-Lb-275 |
0.406 |
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| 2012 |
He HH, Meyer CA, Liu SX, Brown M. Abstract 2960: Factor dependent chromatin structure and nucleosome dynamics Cancer Research. 72: 2960-2960. DOI: 10.1158/1538-7445.Am2012-2960 |
0.474 |
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| 2012 |
Buchwalter G, Brown M. Abstract 2256: PDEF regulation and role as a survival factor in ER positive breast cancer cells Cancer Research. 72: 2256-2256. DOI: 10.1158/1538-7445.Am2012-2256 |
0.502 |
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| 2012 |
Lim E, He H, Chi D, Yeung T, Schnitt S, Liu S, Garber J, Richardson A, Brown M. Abstract PD01-08: Differences in estrogen receptor signaling in non-malignant primary ER-positive breast epithelial cells and breast cancer. Cancer Research. 72. DOI: 10.1158/0008-5472.Sabcs12-Pd01-08 |
0.634 |
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| 2012 |
Jeselsohn R, Regan M, Werner L, Fatima A, He H, Brown M, Iglehart J, Richardson A, Come S. Abstract P1-07-07: Inflammatory gene expression variations in the interval between core needle biopsy and excisional biopsy in early breast cancer Cancer Research. 72. DOI: 10.1158/0008-5472.Sabcs12-P1-07-07 |
0.688 |
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| 2011 |
Fujiki R, Hashiba W, Sekine H, Yokoyama A, Chikanishi T, Ito S, Imai Y, Kim J, He HH, Igarashi K, Kanno J, Ohtake F, Kitagawa H, Roeder RG, Brown M, et al. GlcNAcylation of histone H2B facilitates its monoubiquitination. Nature. 480: 557-60. PMID 22121020 DOI: 10.1038/Nature10656 |
0.302 |
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| 2011 |
Cai C, He HH, Chen S, Coleman I, Wang H, Fang Z, Chen S, Nelson PS, Liu XS, Brown M, Balk SP. Androgen receptor gene expression in prostate cancer is directly suppressed by the androgen receptor through recruitment of lysine-specific demethylase 1. Cancer Cell. 20: 457-71. PMID 22014572 DOI: 10.1016/J.Ccr.2011.09.001 |
0.452 |
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| 2011 |
Tang Q, Chen Y, Meyer C, Geistlinger T, Lupien M, Wang Q, Liu T, Zhang Y, Brown M, Liu XS. A comprehensive view of nuclear receptor cancer cistromes. Cancer Research. 71: 6940-7. PMID 21940749 DOI: 10.1158/0008-5472.Can-11-2091 |
0.825 |
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| 2011 |
Zhang C, Wang L, Wu D, Chen H, Chen Z, Thomas-Ahner JM, Zynger DL, Eeckhoute J, Yu J, Luo J, Brown M, Clinton SK, Nephew KP, Huang TH, Li W, et al. Definition of a FoxA1 Cistrome that is crucial for G1 to S-phase cell-cycle transit in castration-resistant prostate cancer. Cancer Research. 71: 6738-48. PMID 21900400 DOI: 10.1158/0008-5472.Can-11-1882 |
0.445 |
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| 2011 |
Liu T, Ortiz JA, Taing L, Meyer CA, Lee B, Zhang Y, Shin H, Wong SS, Ma J, Lei Y, Pape UJ, Poidinger M, Chen Y, Yeung K, Brown M, et al. Cistrome: an integrative platform for transcriptional regulation studies. Genome Biology. 12: R83. PMID 21859476 DOI: 10.1186/Gb-2011-12-8-R83 |
0.305 |
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| 2011 |
Wang C, Mayer JA, Mazumdar A, Fertuck K, Kim H, Brown M, Brown PH. Estrogen induces c-myc gene expression via an upstream enhancer activated by the estrogen receptor and the AP-1 transcription factor. Molecular Endocrinology (Baltimore, Md.). 25: 1527-38. PMID 21835891 DOI: 10.1210/Me.2011-1037 |
0.435 |
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| 2011 |
Ni M, Chen Y, Lim E, Wimberly H, Bailey ST, Imai Y, Rimm DL, Liu XS, Brown M. Targeting androgen receptor in estrogen receptor-negative breast cancer. Cancer Cell. 20: 119-31. PMID 21741601 DOI: 10.1016/J.Ccr.2011.05.026 |
0.483 |
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| 2011 |
Scott SM, Brown M, Come SE. Emerging data on the efficacy and safety of fulvestrant, a unique antiestrogen therapy for advanced breast cancer Expert Opinion On Drug Safety. 10: 819-826. PMID 21699443 DOI: 10.1517/14740338.2011.595560 |
0.416 |
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| 2011 |
Yang M, Xie W, Mostaghel E, Nakabayashi M, Werner L, Sun T, Pomerantz M, Freedman M, Ross R, Regan M, Sharifi N, Figg WD, Balk S, Brown M, Taplin ME, et al. SLCO2B1 and SLCO1B3 may determine time to progression for patients receiving androgen deprivation therapy for prostate cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: 2565-73. PMID 21606417 DOI: 10.1200/Jco.2010.31.2405 |
0.389 |
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| 2011 |
Meyer CA, He HH, Brown M, Liu XS. BINOCh: binding inference from nucleosome occupancy changes. Bioinformatics (Oxford, England). 27: 1867-8. PMID 21551136 DOI: 10.1093/bioinformatics/btr279 |
0.731 |
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| 2011 |
Baba A, Ohtake F, Okuno Y, Yokota K, Okada M, Imai Y, Ni M, Meyer CA, Igarashi K, Kanno J, Brown M, Kato S. PKA-dependent regulation of the histone lysine demethylase complex PHF2-ARID5B. Nature Cell Biology. 13: 668-75. PMID 21532585 DOI: 10.1038/Ncb2228 |
0.328 |
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| 2011 |
Sérandour AA, Avner S, Percevault F, Demay F, Bizot M, Lucchetti-Miganeh C, Barloy-Hubler F, Brown M, Lupien M, Métivier R, Salbert G, Eeckhoute J. Epigenetic switch involved in activation of pioneer factor FOXA1-dependent enhancers. Genome Research. 21: 555-65. PMID 21233399 DOI: 10.1101/Gr.111534.110 |
0.619 |
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| 2011 |
Frigo DE, Howe MK, Wittmann BM, Brunner AM, Cushman I, Wang Q, Brown M, Means AR, McDonnell DP. CaM kinase kinase beta-mediated activation of the growth regulatory kinase AMPK is required for androgen-dependent migration of prostate cancer cells. Cancer Research. 71: 528-37. PMID 21098087 DOI: 10.1158/0008-5472.Can-10-2581 |
0.43 |
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| 2011 |
Madak-Erdogan Z, Lupien M, Stossi F, Brown M, Katzenellenbogen BS. Genomic collaboration of estrogen receptor alpha and extracellular signal-regulated kinase 2 in regulating gene and proliferation programs. Molecular and Cellular Biology. 31: 226-36. PMID 20956553 DOI: 10.1128/Mcb.00821-10 |
0.66 |
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| 2011 |
Ni M, Chen Y, Bailey ST, Imai Y, Liu XS, Brown M. Abstract 941: Targeting androgen receptor in estrogen receptor-negative breast cancer Cancer Research. 71: 941-941. DOI: 10.1158/1538-7445.Am2011-941 |
0.496 |
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| 2011 |
Wade H, McDonnell D, Brown M. Abstract 4542: Dose-dependent effects of progestins on progesterone receptor activity and target gene expression: less is more Cancer Research. 71: 4542-4542. DOI: 10.1158/1538-7445.Am2011-4542 |
0.466 |
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| 2011 |
Cato L, Brown M. Abstract 260: Identification of the role of linker histone H1 in estrogen receptor binding and activity Cancer Research. 71: 260-260. DOI: 10.1158/1538-7445.Am2011-260 |
0.787 |
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| 2011 |
Malorni L, Giuliano M, Migliaccio I, Wang T, Creighton C, Lupien M, Hilsenbeck S, Healy N, Mazumdar A, Trivedi M, Jeselsohn R, He H, Fu X, Gutierrez C, Brown M, et al. P4-01-18: AP-1 Blockade Potentiates the Anti-Tumor Effect of Endocrine Treatment and Reverts the Resistant Phenotype in Hormone Receptor-Positive Breast Cancer. Cancer Research. 71. DOI: 10.1158/0008-5472.Sabcs11-P4-01-18 |
0.76 |
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| 2011 |
Imai Y, Kondoh S, Inoue K, Brown M, Kato S. Identification of androgen receptor function in osteoblast by genome-wide approach using ChIP-seq Bone. 48. DOI: 10.1016/J.Bone.2011.03.678 |
0.32 |
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| 2010 |
Verzi MP, Shin H, He HH, Sulahian R, Meyer CA, Montgomery RK, Fleet JC, Brown M, Liu XS, Shivdasani RA. Differentiation-specific histone modifications reveal dynamic chromatin interactions and partners for the intestinal transcription factor CDX2. Developmental Cell. 19: 713-26. PMID 21074721 DOI: 10.1016/J.Devcel.2010.10.006 |
0.798 |
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| 2010 |
Lupien M, Meyer CA, Bailey ST, Eeckhoute J, Cook J, Westerling T, Zhang X, Carroll JS, Rhodes DR, Liu XS, Brown M. Growth factor stimulation induces a distinct ER(alpha) cistrome underlying breast cancer endocrine resistance. Genes & Development. 24: 2219-27. PMID 20889718 DOI: 10.1101/Gad.1944810 |
0.792 |
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| 2010 |
Verzi MP, Hatzis P, Sulahian R, Philips J, Schuijers J, Shin H, Freed E, Lynch JP, Dang DT, Brown M, Clevers H, Liu XS, Shivdasani RA. TCF4 and CDX2, major transcription factors for intestinal function, converge on the same cis-regulatory regions. Proceedings of the National Academy of Sciences of the United States of America. 107: 15157-62. PMID 20696899 DOI: 10.1073/Pnas.1003822107 |
0.378 |
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| 2010 |
Ahmadiyeh N, Pomerantz MM, Grisanzio C, Herman P, Jia L, Almendro V, He HH, Brown M, Liu XS, Davis M, Caswell JL, Beckwith CA, Hills A, Macconaill L, Coetzee GA, et al. 8q24 prostate, breast, and colon cancer risk loci show tissue-specific long-range interaction with MYC. Proceedings of the National Academy of Sciences of the United States of America. 107: 9742-6. PMID 20453196 DOI: 10.1073/Pnas.0910668107 |
0.39 |
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| 2010 |
Torres-Arzayus MI, Zhao J, Bronson R, Brown M. Estrogen-dependent and estrogen-independent mechanisms contribute to AIB1-mediated tumor formation. Cancer Research. 70: 4102-11. PMID 20442283 DOI: 10.1158/0008-5472.Can-09-4080 |
0.36 |
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| 2010 |
Badve S, Collins NR, Bhat-Nakshatri P, Turbin D, Leung S, Thorat M, Dunn SE, Geistlinger TR, Carroll JS, Brown M, Bose S, Teitell MA, Nakshatri H. Subcellular localization of activated AKT in estrogen receptor- and progesterone receptor-expressing breast cancers: potential clinical implications. The American Journal of Pathology. 176: 2139-49. PMID 20228224 DOI: 10.2353/Ajpath.2010.090477 |
0.652 |
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| 2010 |
He HH, Meyer CA, Shin H, Bailey ST, Wei G, Wang Q, Zhang Y, Xu K, Ni M, Lupien M, Mieczkowski P, Lieb JD, Zhao K, Brown M, Liu XS. Nucleosome dynamics define transcriptional enhancers. Nature Genetics. 42: 343-7. PMID 20208536 DOI: 10.1038/Ng.545 |
0.826 |
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| 2010 |
Wolfer A, Wittner BS, Irimia D, Flavin RJ, Lupien M, Gunawardane RN, Meyer CA, Lightcap ES, Tamayo P, Mesirov JP, Liu XS, Shioda T, Toner M, Loda M, Brown M, et al. MYC regulation of a "poor-prognosis" metastatic cancer cell state. Proceedings of the National Academy of Sciences of the United States of America. 107: 3698-703. PMID 20133671 DOI: 10.1073/Pnas.0914203107 |
0.663 |
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| 2010 |
Wade HE, Kobayashi S, Eaton ML, Jansen MS, Lobenhofer EK, Lupien M, Geistlinger TR, Zhu W, Nevins JR, Brown M, Otteson DC, McDonnell DP. Multimodal regulation of E2F1 gene expression by progestins. Molecular and Cellular Biology. 30: 1866-77. PMID 20123965 DOI: 10.1128/Mcb.01060-09 |
0.667 |
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| 2010 |
Liu Y, Ni M, Roccaro AM, Leleu X, Zhang Y, Azab AKA, Azab F, Maiso P, Ngo HT, Sacco A, Morgan B, Brown M, Ghobrial I. Promoter-Wide Transcriptional Deregulation In Waldenstrom Macroglobulinemia Blood. 116: 3620-3620. DOI: 10.1182/Blood.V116.21.3620.3620 |
0.393 |
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| 2010 |
Wolfer A, Wittner BS, Irimia D, Flavin RJ, Lupien M, Gunawardane RN, Meyer CA, Lightcap ES, Tamayo P, Mesirov JP, Liu XS, Shioda T, Toner M, Loda M, Brown M, et al. Abstract 3300: MYC regulation of a “poor prognosis” metastatic cancer cell state Cancer Research. 70: 3300-3300. DOI: 10.1158/1538-7445.Am10-3300 |
0.834 |
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| 2010 |
Bailey ST, He HH, Brown M. Abstract 2071: Loss of ER-regulated microRNAs is fundamental to hormone-independent breast cancer cells Cancer Research. 70: 2071-2071. DOI: 10.1158/1538-7445.Am10-2071 |
0.41 |
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| 2009 |
Zhang Q, Gu J, Li L, Liu J, Luo B, Cheung HW, Boehm JS, Ni M, Geisen C, Root DE, Polyak K, Brown M, Richardson AL, Hahn WC, Kaelin WG, et al. Control of cyclin D1 and breast tumorigenesis by the EglN2 prolyl hydroxylase. Cancer Cell. 16: 413-24. PMID 19878873 DOI: 10.1016/J.Ccr.2009.09.029 |
0.607 |
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| 2009 |
Boros J, Donaldson IJ, O'Donnell A, Odrowaz ZA, Zeef L, Lupien M, Meyer CA, Liu XS, Brown M, Sharrocks AD. Elucidation of the ELK1 target gene network reveals a role in the coordinate regulation of core components of the gene regulation machinery. Genome Research. 19: 1963-73. PMID 19687146 DOI: 10.1101/Gr.093047.109 |
0.609 |
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| 2009 |
Wang Q, Li W, Zhang Y, Yuan X, Xu K, Yu J, Chen Z, Beroukhim R, Wang H, Lupien M, Wu T, Regan MM, Meyer CA, Carroll JS, Manrai AK, ... ... Brown M, et al. Androgen receptor regulates a distinct transcription program in androgen-independent prostate cancer. Cell. 138: 245-56. PMID 19632176 DOI: 10.1016/J.Cell.2009.04.056 |
0.761 |
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| 2009 |
Bhat-Nakshatri P, Wang G, Collins NR, Thomson MJ, Geistlinger TR, Carroll JS, Brown M, Hammond S, Srour EF, Liu Y, Nakshatri H. Estradiol-regulated microRNAs control estradiol response in breast cancer cells. Nucleic Acids Research. 37: 4850-61. PMID 19528081 DOI: 10.1093/Nar/Gkp500 |
0.605 |
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| 2009 |
Eeckhoute J, Lupien M, Brown M. Combining chromatin immunoprecipitation and oligonucleotide tiling arrays (ChIP-Chip) for functional genomic studies. Methods in Molecular Biology (Clifton, N.J.). 556: 155-64. PMID 19488877 DOI: 10.1007/978-1-60327-192-9_11 |
0.577 |
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| 2009 |
Nucera C, Eeckhoute J, Finn S, Carroll JS, Ligon AH, Priolo C, Fadda G, Toner M, Sheils O, Attard M, Pontecorvi A, Nose V, Loda M, Brown M. FOXA1 is a potential oncogene in anaplastic thyroid carcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 3680-9. PMID 19470727 DOI: 10.1158/1078-0432.Ccr-08-3155 |
0.522 |
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| 2009 |
Frigo DE, Sherk AB, Wittmann BM, Norris JD, Wang Q, Joseph JD, Toner AP, Brown M, McDonnell DP. Induction of Kruppel-like factor 5 expression by androgens results in increased CXCR4-dependent migration of prostate cancer cells in vitro. Molecular Endocrinology (Baltimore, Md.). 23: 1385-96. PMID 19460858 DOI: 10.1210/Me.2009-0010 |
0.46 |
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| 2009 |
Lupien M, Brown M. Cistromics of hormone-dependent cancer. Endocrine-Related Cancer. 16: 381-9. PMID 19369485 DOI: 10.1677/Erc-09-0038 |
0.726 |
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| 2009 |
Lupien M, Eeckhoute J, Meyer CA, Krum SA, Rhodes DR, Liu XS, Brown M. Coactivator function defines the active estrogen receptor alpha cistrome. Molecular and Cellular Biology. 29: 3413-23. PMID 19364822 DOI: 10.1128/Mcb.00020-09 |
0.649 |
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| 2009 |
Sun T, Wang Q, Balk S, Brown M, Lee GS, Kantoff P. The role of microRNA-221 and microRNA-222 in androgen-independent prostate cancer cell lines. Cancer Research. 69: 3356-63. PMID 19351832 DOI: 10.1158/0008-5472.Can-08-4112 |
0.307 |
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| 2009 |
Nwachukwu JC, Mita P, Ruoff R, Ha S, Wang Q, Huang SJ, Taneja SS, Brown M, Gerald WL, Garabedian MJ, Logan SK. Genome-wide impact of androgen receptor trapped clone-27 loss on androgen-regulated transcription in prostate cancer cells. Cancer Research. 69: 3140-7. PMID 19318562 DOI: 10.1158/0008-5472.CAN-08-3738 |
0.403 |
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| 2009 |
Xia X, Lemieux ME, Li W, Carroll JS, Brown M, Liu XS, Kung AL. Integrative analysis of HIF binding and transactivation reveals its role in maintaining histone methylation homeostasis. Proceedings of the National Academy of Sciences of the United States of America. 106: 4260-5. PMID 19255431 DOI: 10.1073/Pnas.0810067106 |
0.679 |
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| 2009 |
Eeckhoute J, Lupien M, Meyer CA, Verzi MP, Shivdasani RA, Liu XS, Brown M. Cell-type selective chromatin remodeling defines the active subset of FOXA1-bound enhancers. Genome Research. 19: 372-80. PMID 19129543 DOI: 10.1101/Gr.084582.108 |
0.617 |
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| 2009 |
Hurtado A, Holmes KA, Geistlinger TR, Hutcheson IR, Nicholson RI, Brown M, Jiang J, Howat WJ, Ali S, Carroll JS. Regulation of ERBB2 by oestrogen receptor-PAX2 determines response to tamoxifen (Nature (2008) 456, (663-666)) Nature. 457: 1168. DOI: 10.1038/Nature07835 |
0.507 |
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| 2008 |
Hurtado A, Holmes KA, Geistlinger TR, Hutcheson IR, Nicholson RI, Brown M, Jiang J, Howat WJ, Ali S, Carroll JS. Regulation of ERBB2 by oestrogen receptor-PAX2 determines response to tamoxifen. Nature. 456: 663-6. PMID 19005469 DOI: 10.1038/Nature07483 |
0.673 |
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| 2008 |
Bhat-Nakshatri P, Wang G, Appaiah H, Luktuke N, Carroll JS, Geistlinger TR, Brown M, Badve S, Liu Y, Nakshatri H. AKT alters genome-wide estrogen receptor alpha binding and impacts estrogen signaling in breast cancer. Molecular and Cellular Biology. 28: 7487-503. PMID 18838536 DOI: 10.1128/Mcb.00799-08 |
0.655 |
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| 2008 |
Krum SA, Miranda-Carboni GA, Lupien M, Eeckhoute J, Carroll JS, Brown M. Unique ERalpha cistromes control cell type-specific gene regulation. Molecular Endocrinology (Baltimore, Md.). 22: 2393-406. PMID 18818283 DOI: 10.1210/Me.2008-0100 |
0.729 |
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| 2008 |
Holmes KA, Song JS, Liu XS, Brown M, Carroll JS. Nkx3-1 and LEF-1 function as transcriptional inhibitors of estrogen receptor activity. Cancer Research. 68: 7380-5. PMID 18794125 DOI: 10.1158/0008-5472.Can-08-0133 |
0.821 |
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| 2008 |
Agoulnik IU, Bingman WE, Nakka M, Li W, Wang Q, Liu XS, Brown M, Weigel NL. Target gene-specific regulation of androgen receptor activity by p42/p44 mitogen-activated protein kinase. Molecular Endocrinology (Baltimore, Md.). 22: 2420-32. PMID 18787043 DOI: 10.1210/Me.2007-0481 |
0.455 |
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| 2008 |
Setlur SR, Mertz KD, Hoshida Y, Demichelis F, Lupien M, Perner S, Sboner A, Pawitan Y, Andrén O, Johnson LA, Tang J, Adami HO, Calza S, Chinnaiyan AM, Rhodes D, ... ... Brown M, et al. Estrogen-dependent signaling in a molecularly distinct subclass of aggressive prostate cancer. Journal of the National Cancer Institute. 100: 815-25. PMID 18505969 DOI: 10.1093/Jnci/Djn150 |
0.651 |
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| 2008 |
Yang XH, Richardson AL, Torres-Arzayus MI, Zhou P, Sharma C, Kazarov AR, Andzelm MM, Strominger JL, Brown M, Hemler ME. CD151 accelerates breast cancer by regulating alpha 6 integrin function, signaling, and molecular organization. Cancer Research. 68: 3204-13. PMID 18451146 DOI: 10.1158/0008-5472.Can-07-2949 |
0.324 |
|
| 2008 |
Krum SA, Brown M. Unraveling estrogen action in osteoporosis. Cell Cycle (Georgetown, Tex.). 7: 1348-52. PMID 18418063 DOI: 10.4161/Cc.7.10.5892 |
0.367 |
|
| 2008 |
Li W, Carroll JS, Brown M, Liu xS. xMAN: extreme MApping of OligoNucleotides. Bmc Genomics. 9: S20. PMID 18366610 DOI: 10.1186/1471-2164-9-S1-S20 |
0.747 |
|
| 2008 |
Lupien M, Eeckhoute J, Meyer CA, Wang Q, Zhang Y, Li W, Carroll JS, Liu XS, Brown M. FoxA1 translates epigenetic signatures into enhancer-driven lineage-specific transcription. Cell. 132: 958-70. PMID 18358809 DOI: 10.1016/J.Cell.2008.01.018 |
0.706 |
|
| 2008 |
Leleu X, Eeckhoute J, Jia X, Roccaro AM, Moreau AS, Farag M, Sacco A, Ngo HT, Runnels J, Melhem MR, Burwick N, Azab A, Azab F, Hunter Z, Hatjiharissi E, ... ... Brown M, et al. Targeting NF-kappaB in Waldenstrom macroglobulinemia. Blood. 111: 5068-77. PMID 18334673 DOI: 10.1182/Blood-2007-09-115170 |
0.319 |
|
| 2008 |
Bao BY, Chuang BF, Wang Q, Sartor O, Balk SP, Brown M, Kantoff PW, Lee GS. Androgen receptor mediates the expression of UDP-glucuronosyltransferase 2 B15 and B17 genes. The Prostate. 68: 839-48. PMID 18302198 DOI: 10.1002/Pros.20749 |
0.416 |
|
| 2008 |
Johnson DS, Li W, Gordon DB, Bhattacharjee A, Curry B, Ghosh J, Brizuela L, Carroll JS, Brown M, Flicek P, Koch CM, Dunham I, Bieda M, Xu X, Farnham PJ, et al. Systematic evaluation of variability in ChIP-chip experiments using predefined DNA targets. Genome Research. 18: 393-403. PMID 18258921 DOI: 10.1101/Gr.7080508 |
0.507 |
|
| 2008 |
Krum SA, Miranda-Carboni GA, Hauschka PV, Carroll JS, Lane TF, Freedman LP, Brown M. Estrogen protects bone by inducing Fas ligand in osteoblasts to regulate osteoclast survival. The Embo Journal. 27: 535-45. PMID 18219273 DOI: 10.1038/Sj.Emboj.7601984 |
0.544 |
|
| 2008 |
Frietze S, Lupien M, Silver PA, Brown M. CARM1 regulates estrogen-stimulated breast cancer growth through up-regulation of E2F1. Cancer Research. 68: 301-6. PMID 18172323 DOI: 10.1158/0008-5472.Can-07-1983 |
0.68 |
|
| 2007 |
Wang Q, Li W, Liu XS, Carroll JS, Jänne OA, Keeton EK, Chinnaiyan AM, Pienta KJ, Brown M. A hierarchical network of transcription factors governs androgen receptor-dependent prostate cancer growth. Molecular Cell. 27: 380-92. PMID 17679089 DOI: 10.1016/J.Molcel.2007.05.041 |
0.656 |
|
| 2007 |
Eeckhoute J, Keeton EK, Lupien M, Krum SA, Carroll JS, Brown M. Positive cross-regulatory loop ties GATA-3 to estrogen receptor alpha expression in breast cancer. Cancer Research. 67: 6477-83. PMID 17616709 DOI: 10.1158/0008-5472.Can-07-0746 |
0.735 |
|
| 2007 |
Durand M, Kolpak A, Farrell T, Elliott NA, Shao W, Brown M, Volkert MR. The OXR domain defines a conserved family of eukaryotic oxidation resistance proteins. Bmc Cell Biology. 8: 13. PMID 17391516 DOI: 10.1186/1471-2121-8-13 |
0.687 |
|
| 2006 |
Torres-Arzayus MI, Yuan J, DellaGatta JL, Lane H, Kung AL, Brown M. Targeting the AIB1 oncogene through mammalian target of rapamycin inhibition in the mammary gland. Cancer Research. 66: 11381-8. PMID 17145884 DOI: 10.1158/0008-5472.Can-06-2316 |
0.633 |
|
| 2006 |
Carroll JS, Meyer CA, Song J, Li W, Geistlinger TR, Eeckhoute J, Brodsky AS, Keeton EK, Fertuck KC, Hall GF, Wang Q, Bekiranov S, Sementchenko V, Fox EA, Silver PA, ... ... Brown M, et al. Genome-wide analysis of estrogen receptor binding sites. Nature Genetics. 38: 1289-97. PMID 17013392 DOI: 10.1038/Ng1901 |
0.666 |
|
| 2006 |
Eeckhoute J, Carroll JS, Geistlinger TR, Torres-Arzayus MI, Brown M. A cell-type-specific transcriptional network required for estrogen regulation of cyclin D1 and cell cycle progression in breast cancer. Genes & Development. 20: 2513-26. PMID 16980581 DOI: 10.1101/Gad.1446006 |
0.679 |
|
| 2006 |
Johnson WE, Li W, Meyer CA, Gottardo R, Carroll JS, Brown M, Liu XS. Model-based analysis of tiling-arrays for ChIP-chip. Proceedings of the National Academy of Sciences of the United States of America. 103: 12457-62. PMID 16895995 DOI: 10.1073/Pnas.0601180103 |
0.506 |
|
| 2006 |
Carroll DK, Carroll JS, Leong CO, Cheng F, Brown M, Mills AA, Brugge JS, Ellisen LW. p63 regulates an adhesion programme and cell survival in epithelial cells. Nature Cell Biology. 8: 551-61. PMID 16715076 DOI: 10.1038/Ncb1420 |
0.556 |
|
| 2006 |
Richardson AL, Wang ZC, De Nicolo A, Lu X, Brown M, Miron A, Liao X, Iglehart JD, Livingston DM, Ganesan S. X chromosomal abnormalities in basal-like human breast cancer. Cancer Cell. 9: 121-32. PMID 16473279 DOI: 10.1016/J.Ccr.2006.01.013 |
0.504 |
|
| 2006 |
Come SE, Buzdar AU, Ingle JN, Arteaga CL, Brown M, Dowsett M, Hilsenbeck SG, Kumar R, Johnston SR, Lee AV, Paik S, Pritchard KI, Winer EP, Hart C. Proceedings of the Fifth International Conference on Recent Advances and Future Directions in Endocrine Therapy for Breast Cancer: conference summary statement. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 997s-1000s. PMID 16467115 DOI: 10.1158/1078-0432.Ccr-05-2268 |
0.365 |
|
| 2006 |
Carroll JS, Brown M. Estrogen receptor target gene: an evolving concept. Molecular Endocrinology (Baltimore, Md.). 20: 1707-14. PMID 16396959 DOI: 10.1210/Me.2005-0334 |
0.634 |
|
| 2006 |
Colilla S, Kantoff PW, Neuhausen SL, Godwin AK, Daly MB, Narod SA, Garber JE, Lynch HT, Brown M, Weber BL, Rebbeck TR. The joint effect of smoking and AIB1 on breast cancer risk in BRCA1 mutation carriers. Carcinogenesis. 27: 599-605. PMID 16244359 DOI: 10.1093/Carcin/Bgi246 |
0.343 |
|
| 2005 |
Wang Q, Carroll JS, Brown M. Spatial and temporal recruitment of androgen receptor and its coactivators involves chromosomal looping and polymerase tracking. Molecular Cell. 19: 631-42. PMID 16137620 DOI: 10.1016/J.Molcel.2005.07.018 |
0.63 |
|
| 2005 |
Carroll JS, Liu XS, Brodsky AS, Li W, Meyer CA, Szary AJ, Eeckhoute J, Shao W, Hestermann EV, Geistlinger TR, Fox EA, Silver PA, Brown M. Chromosome-wide mapping of estrogen receptor binding reveals long-range regulation requiring the forkhead protein FoxA1. Cell. 122: 33-43. PMID 16009131 DOI: 10.1016/J.Cell.2005.05.008 |
0.813 |
|
| 2005 |
Georgescu SP, Li JH, Lu Q, Karas RH, Brown M, Mendelsohn ME. Modulator recognition factor 1, an AT-rich interaction domain family member, is a novel corepressor for estrogen receptor α Molecular Endocrinology. 19: 2491-2501. PMID 15941852 DOI: 10.1210/Me.2004-0311 |
0.429 |
|
| 2005 |
Febbo PG, Lowenberg M, Thorner AR, Brown M, Loda M, Golub TR. Androgen mediated regulation and functional implications of fkbp51 expression in prostate cancer. The Journal of Urology. 173: 1772-7. PMID 15821585 DOI: 10.1097/01.Ju.0000155845.44729.Ba |
0.462 |
|
| 2005 |
Keeton EK, Brown M. Cell cycle progression stimulated by tamoxifen-bound estrogen receptor-alpha and promoter-specific effects in breast cancer cells deficient in N-CoR and SMRT. Molecular Endocrinology (Baltimore, Md.). 19: 1543-54. PMID 15802375 DOI: 10.1210/Me.2004-0395 |
0.49 |
|
| 2004 |
Torres-Arzayus MI, Font de Mora J, Yuan J, Vazquez F, Bronson R, Rue M, Sellers WR, Brown M. High tumor incidence and activation of the PI3K/AKT pathway in transgenic mice define AIB1 as an oncogene. Cancer Cell. 6: 263-74. PMID 15380517 DOI: 10.1016/J.Ccr.2004.06.027 |
0.577 |
|
| 2004 |
Shao W, Keeton EK, McDonnell DP, Brown M. Coactivator AIB1 links estrogen receptor transcriptional activity and stability. Proceedings of the National Academy of Sciences of the United States of America. 101: 11599-604. PMID 15289619 DOI: 10.1073/Pnas.0402997101 |
0.751 |
|
| 2004 |
Shao W, Brown M. Advances in estrogen receptor biology: Prospects for improvements in targeted breast cancer therapy Breast Cancer Research. 6: 39-52. PMID 14680484 DOI: 10.1186/Bcr742 |
0.75 |
|
| 2003 |
Hestermann EV, Brown M. Agonist and chemopreventative ligands induce differential transcriptional cofactor recruitment by aryl hydrocarbon receptor. Molecular and Cellular Biology. 23: 7920-7925. PMID 14560034 DOI: 10.1128/Mcb.23.21.7920-7925.2003 |
0.39 |
|
| 2002 |
Shao W, Halachmi S, Brown M. ERAP140, a conserved tissue-specific nuclear receptor coactivator Molecular and Cellular Biology. 22: 3358-3372. PMID 11971969 DOI: 10.1128/Mcb.22.10.3358-3372.2002 |
0.74 |
|
| 2002 |
Shang Y, Myers M, Brown M. Formation of the androgen receptor transcription complex. Molecular Cell. 9: 601-10. PMID 11931767 DOI: 10.1016/S1097-2765(02)00471-9 |
0.677 |
|
| 2002 |
Shang Y, Brown M. Molecular determinants for the tissue specificity of SERMs. Science (New York, N.Y.). 295: 2465-8. PMID 11923541 DOI: 10.1126/Science.1068537 |
0.711 |
|
| 2002 |
DiRenzo J, Signoretti S, Nakamura N, Rivera-Gonzalez R, Sellers W, Loda M, Brown M. Growth factor requirements and basal phenotype of an immortalized mammary epithelial cell line. Cancer Research. 62: 89-98. PMID 11782364 |
0.737 |
|
| 2001 |
Yahata T, Shao W, Endoh H, Hur J, Coser KR, Sun H, Ueda Y, Kato S, Isselbacher KJ, Brown M, Shioda T. Selective coactivation of estrogen-dependent transcription by CITED1 CBP/p300-binding protein Genes & Development. 15: 2598-2612. PMID 11581164 DOI: 10.1101/Gad.906301 |
0.769 |
|
| 2000 |
Shang Y, Hu X, DiRenzo J, Lazar MA, Brown M. Cofactor dynamics and sufficiency in estrogen receptor-regulated transcription Cell. 103: 843-852. PMID 11136970 DOI: 10.1016/S0092-8674(00)00188-4 |
0.815 |
|
| 2000 |
DiRenzo J, Shang Y, Phelan M, Sif S, Myers M, Kingston R, Brown M. BRG-1 is recruited to estrogen-responsive promoters and cooperates with factors involved in histone acetylation. Molecular and Cellular Biology. 20: 7541-9. PMID 11003650 DOI: 10.1128/Mcb.20.20.7541-7549.2000 |
0.818 |
|
| 2000 |
Mora JFd, Brown M. AIB1 Is a Conduit for Kinase-Mediated Growth Factor Signaling to the Estrogen Receptor Molecular and Cellular Biology. 20: 5041-5047. PMID 10866661 DOI: 10.1128/Mcb.20.14.5041-5047.2000 |
0.42 |
|
| 2000 |
Poelzl G, Kasai Y, Mochizuki N, Shaul PW, Brown M, Mendelsohn ME. Specific association of estrogen receptor β with the cell cycle spindle assembly checkpoint protein, MAD2 Proceedings of the National Academy of Sciences of the United States of America. 97: 2836-2839. PMID 10706629 DOI: 10.1073/Pnas.050580997 |
0.396 |
|
| 2000 |
DiRenzo J, Rivera-Gonzalez R, Brown M. Mammary epithelial cells immortalized by over-expression of the catalytic subunit of human telomerase may represent a model for mammary epithelial differentiation Breast Cancer Research. 2. DOI: 10.1186/Bcr121 |
0.68 |
|
| 2000 |
Platz EA, Giovannucci E, Brown M, Cieluch C, Shepard TF, Stampfer MJ, Kantoff PW. Amplified in breast cancer-1 glutamine repeat and prostate cancer risk Prostate Journal. 2: 27-32. DOI: 10.1046/J.1525-1411.2000.15005.X |
0.443 |
|
| 1999 |
Rebbeck TR, Kantoff PW, Krithivas K, Neuhausen S, Blackwood MA, Godwin AK, Daly MB, Narod SA, Garber JE, Lynch HT, Weber BL, Brown M. Modification of BRCA1-associated breast cancer risk by the polymorphic androgen-receptor CAG repeat. American Journal of Human Genetics. 64: 1371-7. PMID 10205268 DOI: 10.1086/302366 |
0.408 |
|
| 1999 |
Hanstein B, Liu H, Yancisin MC, Brown M. Functional analysis of a novel estrogen receptor-beta isoform. Molecular Endocrinology. 13: 129-137. PMID 9892018 DOI: 10.1210/Mend.13.1.0234 |
0.393 |
|
| 1999 |
Shim WS, DiRenzo J, DeCaprio JA, Santen RJ, Brown M, Jeng MH. Segregation of steroid receptor coactivator-1 from steroid receptors in mammary epithelium. Proceedings of the National Academy of Sciences of the United States of America. 96: 208-13. PMID 9874797 DOI: 10.1073/Pnas.96.1.208 |
0.777 |
|
| 1998 |
Kantoff P, Giovannucci E, Brown M. The androgen receptor CAG repeat polymorphism and its relationship to prostate cancer Biochimica Et Biophysica Acta. 1378: 1-5. PMID 9875243 DOI: 10.1016/S0304-419X(98)00023-7 |
0.396 |
|
| 1998 |
Seol W, Hanstein B, Brown M, Moore DD. Inhibition of estrogen receptor action by the orphan receptor SHP (short heterodimer partner). Molecular Endocrinology (Baltimore, Md.). 12: 1551-7. PMID 9773978 DOI: 10.1210/Mend.12.10.0184 |
0.367 |
|
| 1997 |
Neuman E, Ladha MH, Lin N, Upton TM, Miller SJ, DiRenzo J, Pestell RG, Hinds PW, Dowdy SF, Brown M, Ewen ME. Cyclin D1 stimulation of estrogen receptor transcriptional activity independent of cdk4. Molecular and Cellular Biology. 17: 5338-47. PMID 9271411 DOI: 10.1128/Mcb.17.9.5338 |
0.804 |
|
| 1997 |
Treilleux I, Peloux N, Brown M, Sergeant A. Human Estrogen Receptor (ER) Gene Promoter-P1: Estradiol-Independent Activity and Estradiol Inducibility in ER+ and ER− Cells Molecular Endocrinology. 11: 1319-1331. PMID 9259322 DOI: 10.1210/Mend.11.9.9973 |
0.439 |
|
| 1997 |
Giovannucci E, Stampfer MJ, Krithivas K, Brown M, Dahl D, Brufsky A, Talcott J, Hennekens CH, Kantoff PW. The CAG repeat within the androgen receptor gene and its relationship to prostate cancer. Proceedings of the National Academy of Sciences of the United States of America. 94: 3320-3. PMID 9096391 DOI: 10.1073/Pnas.94.7.3320 |
0.425 |
|
| 1997 |
Tang Z, Treilleux I, Brown M. A transcriptional enhancer required for the differential expression of the human estrogen receptor in breast cancers. Molecular and Cellular Biology. 17: 1274-1280. PMID 9032254 DOI: 10.1128/Mcb.17.3.1274 |
0.466 |
|
| 1996 |
Hanstein B, Eckner R, DiRenzo J, Halachmi S, Liu H, Searcy B, Kurokawa R, Brown M. p300 is a component of an estrogen receptor coactivator complex Proceedings of the National Academy of Sciences of the United States of America. 93: 11540-11545. PMID 8876171 DOI: 10.1073/Pnas.93.21.11540 |
0.724 |
|
| 1995 |
Yu K, Bayona W, Kallen CB, Harding HP, Ravera CP, McMahon G, Brown M, Lazar MA. Differential activation of peroxisome proliferator-activated receptors by eicosanoids. The Journal of Biological Chemistry. 270: 23975-83. PMID 7592593 DOI: 10.1074/Jbc.270.41.23975 |
0.331 |
|
| 1995 |
Kurokawa R, Söderström M, Hörlein A, Halachmi S, Brown M, Rosenfeld MG, Glass CK. Polarity-specific activities of retinoic acid receptors determined by a co-repressor. Nature. 377: 451-4. PMID 7566126 DOI: 10.1038/377451A0 |
0.351 |
|
| 1994 |
Halachmi S, Marden E, Martin G, Mackay H, Abbondanza C, Brown M. Estrogen receptor-associated proteins: possible mediators of hormone-induced transcription Science. 264: 1455-1458. PMID 8197458 DOI: 10.1126/Science.8197458 |
0.441 |
|
| 1994 |
Brown M. Estrogen Receptor Molecular Biology Hematology/Oncology Clinics of North America. 8: 101-112. DOI: 10.1016/S0889-8588(18)30189-8 |
0.419 |
|
| 1991 |
Kjems J, Brown M, Chang DD, Sharp PA. Structural analysis of the interaction between the human immunodeficiency virus Rev protein and the Rev response element. Proceedings of the National Academy of Sciences of the United States of America. 88: 683-7. PMID 1992459 DOI: 10.1073/Pnas.88.3.683 |
0.593 |
|
| 1987 |
Brown M, Figge J, Hansen U, Wright C, Jeang KT, Khoury G, Livingston DM, Roberts TM. lac repressor can regulate expression from a hybrid SV40 early promoter containing a lac operator in animal cells. Cell. 49: 603-12. PMID 3034429 DOI: 10.1016/0092-8674(87)90536-8 |
0.783 |
|
| 1987 |
Bikel I, Montano X, Agha ME, Brown M, McCormack M, Boltax J, Livingston DM. SV40 small t antigen enhances the transformation activity of limiting concentrations of SV40 large T antigen Cell. 48: 321-330. PMID 3026642 DOI: 10.1016/0092-8674(87)90435-1 |
0.454 |
|
| 1986 |
Brown M, McCormack M, Zinn KG, Farrell MP, Bikel I, Livingston DM. A recombinant murine retrovirus for simian virus 40 large T cDNA transforms mouse fibroblasts to anchorage-independent growth. Journal of Virology. 60: 290-3. PMID 3018293 DOI: 10.1128/Jvi.60.1.290-293.1986 |
0.454 |
|
| 1985 |
Lynch DC, Zimmerman TS, Collins CJ, Brown M, Morin MJ, Ling EH, Livingston DM. Molecular cloning of cDNA for human von Willebrand factor: authentication by a new method. Cell. 41: 49-56. PMID 3873280 DOI: 10.1016/0092-8674(85)90060-1 |
0.501 |
|
| 1981 |
Goldman N, Brown M, Khoury G. Modification of SV40 T antigen by poly ADP-ribosylation Cell. 24: 567-572. PMID 7237559 DOI: 10.1016/0092-8674(81)90347-0 |
0.573 |
|
| 1977 |
Ferdinand F, Brown M, Khoury G. Characterization of early simian virus 40 transcriptional complexes: late transcription in the absence of detectable DNA replication Proceedings of the National Academy of Sciences of the United States of America. 74: 5443-5447. PMID 202957 DOI: 10.1073/Pnas.74.12.5443 |
0.59 |
|
| 1977 |
Kuster JM, Mora PT, Brown M, Khoury G. Immunologic selection against simian virus-40 transformed cells: Concomitant loss of viral antigens and early viral gene sequences Proceedings of the National Academy of Sciences of the United States of America. 74: 4796-4800. PMID 200932 DOI: 10.1073/Pnas.74.11.4796 |
0.592 |
|
| 1976 |
Khoury G, Carter BJ, Ferdinand FJ, Howley PM, Brown M, Martin MA. Genome localization of simian virus 40 RNA species. Journal of Virology. 17: 832-40. PMID 176448 DOI: 10.1128/Jvi.17.3.832-840.1976 |
0.562 |
|
| 1974 |
Khoury G, Howley P, Brown M, Martin M. The Detection and Quantitation of SV40 Nucleic Acid Sequences Using Single-stranded SV40 DNA Probes Cold Spring Harbor Symposia On Quantitative Biology. 39: 147-152. PMID 169053 DOI: 10.1101/Sqb.1974.039.01.020 |
0.534 |
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