Richard T Eastman - Publications

Affiliations: 
National Insitutes of Health, Bethesda, MD, United States 
Area:
Microbiology, Infectious Diseases, Malaria

26 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Kearney SE, Zahoránszky-Kőhalmi G, Brimacombe KR, Henderson MJ, Lynch C, Zhao T, Wan KK, Itkin Z, Dillon C, Shen M, Cheff DM, Lee TD, Bougie D, Cheng K, Coussens NP, ... ... Eastman RT, et al. Canvass: A Crowd-Sourced, Natural-Product Screening Library for Exploring Biological Space. Acs Central Science. 4: 1727-1741. PMID 30648156 DOI: 10.1021/acscentsci.8b00747  0.4
2018 Sá JM, Kaslow SR, Krause MA, Melendez-Muniz VA, Salzman RE, Kite WA, Zhang M, Moraes Barros RR, Mu J, Han PK, Mershon JP, Figan CE, Caleon RL, Rahman RS, Gibson TJ, ... ... Eastman RT, et al. Artemisinin resistance phenotypes and K13 inheritance in a cross and model. Proceedings of the National Academy of Sciences of the United States of America. PMID 30455312 DOI: 10.1073/pnas.1813386115  0.4
2017 Lacerda-Queiroz N, Riteau N, Eastman RT, Bock KW, Orandle MS, Moore IN, Sher A, Long CA, Jankovic D, Su XZ. Mechanism of splenic cell death and host mortality in a Plasmodium yoelii malaria model. Scientific Reports. 7: 10438. PMID 28874800 DOI: 10.1038/s41598-017-10776-2  0.4
2017 Nair SC, Xu R, Pattaradilokrat S, Wu J, Qi Y, Zilversmit M, Ganesan S, Nagarajan V, Eastman RT, Orandle MS, Tan JC, Myers TG, Liu S, Long CA, Li J, et al. A Plasmodium yoelii HECT-like E3 ubiquitin ligase regulates parasite growth and virulence. Nature Communications. 8: 223. PMID 28790316 DOI: 10.1038/s41467-017-00267-3  0.4
2016 Eastman RT, Khine P, Huang R, Thomas CJ, Su XZ. PfCRT and PfMDR1 modulate interactions of artemisinin derivatives and ion channel blockers. Scientific Reports. 6: 25379. PMID 27147113 DOI: 10.1038/srep25379  0.4
2015 Cheng KC, Cao S, Raveh A, MacArthur R, Dranchak P, Chlipala G, Okoneski MT, Guha R, Eastman RT, Yuan J, Schultz PJ, Su XZ, Tamayo-Castillo G, Matainaho T, Clardy J, et al. Actinoramide A Identified as a Potent Antimalarial from Titration-Based Screening of Marine Natural Product Extracts. Journal of Natural Products. PMID 26465675 DOI: 10.1021/acs.jnatprod.5b00489  0.4
2015 Mott BT, Eastman RT, Guha R, Sherlach KS, Siriwardana A, Shinn P, McKnight C, Michael S, Lacerda-Queiroz N, Patel PR, Khine P, Sun H, Kasbekar M, Aghdam N, Fontaine SD, et al. High-throughput matrix screening identifies synergistic and antagonistic antimalarial drug combinations. Scientific Reports. 5: 13891. PMID 26403635 DOI: 10.1038/srep13891  0.4
2015 Qi Y, Zhu F, Eastman RT, Fu Y, Zilversmit M, Pattaradilokrat S, Hong L, Liu S, McCutchan TF, Pan W, Xu W, Li J, Huang F, Su XZ. Regulation of Plasmodium yoelii oocyst development by strain- and stage-specific small-subunit rRNA. Mbio. 6: e00117. PMID 25759501 DOI: 10.1128/mBio.00117-15  0.4
2014 Lisewski AM, Quiros JP, Ng CL, Adikesavan AK, Miura K, Putluri N, Eastman RT, Scanfeld D, Regenbogen SJ, Altenhofen L, Llinás M, Sreekumar A, Long C, Fidock DA, Lichtarge O. Supergenomic network compression and the discovery of EXP1 as a glutathione transferase inhibited by artesunate. Cell. 158: 916-28. PMID 25126794 DOI: 10.1016/j.cell.2014.07.011  0.4
2014 Ojo KK, Eastman RT, Vidadala R, Zhang Z, Rivas KL, Choi R, Lutz JD, Reid MC, Fox AM, Hulverson MA, Kennedy M, Isoherranen N, Kim LM, Comess KM, Kempf DJ, et al. A specific inhibitor of PfCDPK4 blocks malaria transmission: chemical-genetic validation. The Journal of Infectious Diseases. 209: 275-84. PMID 24123773 DOI: 10.1093/infdis/jit522  0.4
2013 Lemieux JE, Kyes SA, Otto TD, Feller AI, Eastman RT, Pinches RA, Berriman M, Su XZ, Newbold CI. Genome-wide profiling of chromosome interactions in Plasmodium falciparum characterizes nuclear architecture and reconfigurations associated with antigenic variation. Molecular Microbiology. 90: 519-37. PMID 23980881 DOI: 10.1111/mmi.12381  0.4
2013 Lim P, Dek D, Try V, Eastman RT, Chy S, Sreng S, Suon S, Mao S, Sopha C, Sam B, Ashley EA, Miotto O, Dondorp AM, White NJ, Su XZ, et al. Ex vivo susceptibility of Plasmodium falciparum to antimalarial drugs in western, northern, and eastern Cambodia, 2011-2012: association with molecular markers. Antimicrobial Agents and Chemotherapy. 57: 5277-83. PMID 23939897 DOI: 10.1128/AAC.00687-13  0.4
2013 Eastman RT, Pattaradilokrat S, Raj DK, Dixit S, Deng B, Miura K, Yuan J, Tanaka TQ, Johnson RL, Jiang H, Huang R, Williamson KC, Lambert LE, Long C, Austin CP, et al. A class of tricyclic compounds blocking malaria parasite oocyst development and transmission. Antimicrobial Agents and Chemotherapy. 57: 425-35. PMID 23129054 DOI: 10.1128/AAC.00920-12  0.4
2011 Adjalley SH, Johnston GL, Li T, Eastman RT, Ekland EH, Eappen AG, Richman A, Sim BK, Lee MC, Hoffman SL, Fidock DA. Quantitative assessment of Plasmodium falciparum sexual development reveals potent transmission-blocking activity by methylene blue. Proceedings of the National Academy of Sciences of the United States of America. 108: E1214-23. PMID 22042867 DOI: 10.1073/pnas.1112037108  0.4
2011 Eastman RT, Dharia NV, Winzeler EA, Fidock DA. Piperaquine resistance is associated with a copy number variation on chromosome 5 in drug-pressured Plasmodium falciparum parasites. Antimicrobial Agents and Chemotherapy. 55: 3908-16. PMID 21576453 DOI: 10.1128/AAC.01793-10  0.4
2009 Eastman RT, Fidock DA. Artemisinin-based combination therapies: a vital tool in efforts to eliminate malaria. Nature Reviews. Microbiology. 7: 864-74. PMID 19881520 DOI: 10.1038/nrmicro2239  0.4
2008 Fidock DA, Eastman RT, Ward SA, Meshnick SR. Recent highlights in antimalarial drug resistance and chemotherapy research. Trends in Parasitology. 24: 537-44. PMID 18938106 DOI: 10.1016/j.pt.2008.09.005  0.4
2007 Gillespie JR, Yokoyama K, Lu K, Eastman RT, Bollinger JG, Van Voorhis WC, Gelb MH, Buckner FS. C-terminal proteolysis of prenylated proteins in trypanosomatids and RNA interference of enzymes required for the post-translational processing pathway of farnesylated proteins. Molecular and Biochemical Parasitology. 153: 115-24. PMID 17397944 DOI: 10.1016/j.molbiopara.2007.02.009  0.4
2007 Eastman RT, White J, Hucke O, Yokoyama K, Verlinde CL, Hast MA, Beese LS, Gelb MH, Rathod PK, Van Voorhis WC. Resistance mutations at the lipid substrate binding site of Plasmodium falciparum protein farnesyltransferase. Molecular and Biochemical Parasitology. 152: 66-71. PMID 17208314 DOI: 10.1016/j.molbiopara.2006.11.012  0.36
2006 Eastman RT, Buckner FS, Yokoyama K, Gelb MH, Van Voorhis WC. Fighting parasitic disease by blocking protein farnesylation Journal of Lipid Research. 47: 233-240. PMID 16339110 DOI: 10.1194/jlr.R500016-JLR200  0.4
2005 Eastman RT, Barrett LK, Dupuis K, Buckner FS, Van Voorhis WC. Leishmania inactivation in human pheresis platelets by a psoralen (amotosalen HCl) and long-wavelength ultraviolet irradiation Transfusion. 45: 1459-1463. PMID 16131378 DOI: 10.1111/j.1537-2995.2005.00552.x  0.4
2005 Buckner FS, Eastman RT, Yokoyama K, Gelb MH, Van Voorhis WC. Protein farnesyl transferase inhibitors for the treatment of malaria and African trypanosomiasis Current Opinion in Investigational Drugs. 6: 791-797. PMID 16121685  0.4
2005 Eastman RT, White J, Hucke O, Bauer K, Yokoyama K, Nallan L, Chakrabarti D, Verlinde CL, Gelb MH, Rathod PK, Van Voorhis WC. Resistance to a protein farnesyltransferase inhibitor in Plasmodium falciparum. The Journal of Biological Chemistry. 280: 13554-9. PMID 15661734 DOI: 10.1074/jbc.M413556200  0.36
2003 Hinshaw JC, Suh DY, Garnier P, Buckner FS, Eastman RT, Matsuda SP, Joubert BM, Coppens I, Joiner KA, Merali S, Nash TE, Prestwich GD. Oxidosqualene cyclase inhibitors as antimicrobial agents. Journal of Medicinal Chemistry. 46: 4240-3. PMID 13678402 DOI: 10.1021/jm034126t  0.4
2003 Van Voorhis WC, Barrett LK, Eastman RT, Alfonso R, Dupuis K. Trypanosoma cruzi inactivation in human platelet concentrates and plasma by a psoralen (Amotosalen HCl) and long-wavelength UV Antimicrobial Agents and Chemotherapy. 47: 475-479. PMID 12543646 DOI: 10.1128/AAC.47.2.475-479.2003  0.4
2002 Buckner FS, Eastman RT, Nepomuceno-Silva JL, Speelmon EC, Myler PJ, Van Voorhis WC, Yokoyama K. Cloning, heterologous expression, and substrate specificities of protein farnesyltransferases from Trypanosoma cruzi and Leishmania major. Molecular and Biochemical Parasitology. 122: 181-8. PMID 12106872 DOI: 10.1016/S0166-6851(02)00099-3  0.4
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