Ronit Satchi-Fainaro - Publications

Affiliations: 
Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv-Yafo, Tel Aviv District, Israel 

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Year Citation  Score
2024 Liubomirski Y, Tiram G, Scomparin A, Gnaim S, Das S, Gholap S, Ge L, Yeini E, Shelef O, Zauberman A, Berger N, Kalimi D, Toister-Achituv M, Schröter C, Dickgiesser S, ... ... Satchi-Fainaro R, et al. Potent antitumor activity of anti-HER2 antibody-topoisomerase I inhibitor conjugate based on self-immolative dendritic dimeric-linker. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 38228272 DOI: 10.1016/j.jconrel.2024.01.025  0.323
2023 Matos AI, Peres C, Carreira B, Moura LIF, Acúrcio RC, Vogel T, Wegener E, Ribeiro F, Afonso MB, Santos FMF, Martínez-Barriocanal Á, Arango D, Viana AS, Góis PMP, Silva LC, ... ... Satchi-Fainaro R, et al. Polyoxazoline-Based Nanovaccine Synergizes with Tumor-Associated Macrophage Targeting and Anti-PD-1 Immunotherapy against Solid Tumors. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). e2300299. PMID 37434063 DOI: 10.1002/advs.202300299  0.314
2023 Ofek P, Yeini E, Arad G, Danilevsky A, Pozzi S, Luna CB, Dangoor SI, Grossman R, Ram Z, Shomron N, Brem H, Hyde TM, Geiger T, Satchi-Fainaro R. Deoxyhypusine hydroxylase: A novel therapeutic target differentially expressed in short-term vs long-term survivors of glioblastoma. International Journal of Cancer. PMID 37141410 DOI: 10.1002/ijc.34545  0.31
2022 Epshtein Y, Blau R, Pisarevsky E, Koshrovski-Michael S, Ben-Shushan D, Pozzi S, Shenbach-Koltin G, Fridrich L, Buzhor M, Krivitsky A, Dey P, Satchi-Fainaro R. Polyglutamate-based nanoconjugates for image-guided surgery and post-operative melanoma metastases prevention. Theranostics. 12: 6339-6362. PMID 36168618 DOI: 10.7150/thno.72941  0.774
2021 Krivitsky A, Pozzi S, Yeini E, Israeli Dangoor S, Zur T, Golan S, Krivitsky V, Albeck N, Pisarevsky E, Ofek P, Madi A, Satchi-Fainaro R. Sulfonated Amphiphilic Poly(α)glutamate Amine-A Potential siRNA Nanocarrier for the Treatment of Both Chemo-Sensitive and Chemo-Resistant Glioblastoma Tumors. Pharmaceutics. 13. PMID 34959480 DOI: 10.3390/pharmaceutics13122199  0.331
2021 Neufeld L, Yeini E, Reisman N, Shtilerman Y, Ben-Shushan D, Pozzi S, Madi A, Tiram G, Eldar-Boock A, Ferber S, Grossman R, Ram Z, Satchi-Fainaro R. Microengineered perfusable 3D-bioprinted glioblastoma model for in vivo mimicry of tumor microenvironment. Science Advances. 7. PMID 34407932 DOI: 10.1126/sciadv.abi9119  0.302
2020 Pisarevsky E, Blau R, Epshtein Y, Ben-Shushan D, Eldar-Boock A, Tiram G, Koshrovski-Michael S, Scomparin A, Pozzi S, Krivitsky A, Shenbach-Koltin G, Yeini E, Fridrich L, White R, Satchi-Fainaro R. Rational Design of Polyglutamic Acid Delivering an Optimized Combination of Drugs Targeting Mutated BRAF and MEK in Melanoma. Advanced Therapeutics. 3. PMID 35754977 DOI: 10.1002/adtp.202000028  0.695
2019 Zinger A, Koren L, Adir O, Poley M, Alyan M, Yaari Z, Noor N, Krinsky N, Simon A, Gibori H, Krayem M, Mumblat Y, Kasten S, Ofir S, Fridman E, ... ... Satchi-Fainaro R, et al. Collagenase Nanoparticles Enhance the Penetration of Drugs into Pancreatic Tumors. Acs Nano. PMID 31503443 DOI: 10.1021/Acsnano.9B02395  0.44
2019 Doron H, Amer M, Ershaid N, Blazquez R, Shani O, Lahav TG, Cohen N, Adler O, Hakim Z, Pozzi S, Scomparin A, Cohen J, Yassin M, Monteran L, Grossman R, ... ... Satchi-Fainaro R, et al. Inflammatory Activation of Astrocytes Facilitates Melanoma Brain Tropism via the CXCL10-CXCR3 Signaling Axis. Cell Reports. 28: 1785-1798.e6. PMID 31412247 DOI: 10.1016/J.Celrep.2019.07.033  0.339
2019 Malfanti A, Scomparin A, Pozzi S, Gibori H, Krivitsky A, Blau R, Satchi-Fainaro R, Mastrotto F, Caliceti P, Salmaso S. Oligo-guanidyl targeted bioconjugates forming rod shaped polyplexes as a new nanoplatform for oligonucleotide delivery. Journal of Controlled Release : Official Journal of the Controlled Release Society. 310: 58-73. PMID 31400381 DOI: 10.1016/J.Jconrel.2019.08.005  0.315
2019 Conniot J, Scomparin A, Peres C, Yeini E, Pozzi S, Matos AI, Kleiner R, Moura LIF, Zupančič E, Viana AS, Doron H, Gois PMP, Erez N, Jung S, Satchi-Fainaro R, et al. Immunization with mannosylated nanovaccines and inhibition of the immune-suppressing microenvironment sensitizes melanoma to immune checkpoint modulators. Nature Nanotechnology. PMID 31384037 DOI: 10.1038/S41565-019-0512-0  0.327
2018 Krivitsky A, Krivitsky V, Polyak D, Scomparin A, Eliyahu S, Gibori H, Yeini E, Pisarevsky E, Blau R, Satchi-Fainaro R. Molecular Weight-Dependent Activity of Aminated Poly(α)glutamates as siRNA Nanocarriers. Polymers. 10. PMID 30966582 DOI: 10.3390/Polym10050548  0.741
2018 Blau R, Epshtein Y, Pisarevsky E, Tiram G, Israeli Dangoor S, Yeini E, Krivitsky A, Eldar-Boock A, Ben-Shushan D, Gibori H, Scomparin A, Green O, Ben-Nun Y, Merquiol E, Doron H, ... ... Satchi-Fainaro R, et al. Image-guided surgery using near-infrared Turn-ON fluorescent nanoprobes for precise detection of tumor margins. Theranostics. 8: 3437-3460. PMID 30026858 DOI: 10.7150/thno.23853  0.759
2018 Sainz V, Moura LIF, Peres C, Matos AI, Viana AS, Wagner AM, Vela Ramirez JE, Barata T, Gaspar M, Brocchini S, Zloh M, Peppas NA, Satchi-Fainaro R, Florindo HF. α-Galactosylceramide and peptide-based nano-vaccine synergistically induced a strong tumor suppressive effectin melanoma. Acta Biomaterialia. PMID 29940370 DOI: 10.1016/J.Actbio.2018.06.029  0.393
2018 Tiram G, Ferber S, Ofek P, Eldar-Boock A, Ben-Shushan D, Yeini E, Krivitsky A, Blatt R, Almog N, Henkin J, Amsalem O, Yavin E, Cohen G, Lazarovici P, Lee JS, ... ... Satchi-Fainaro R, et al. Reverting the molecular fingerprint of tumor dormancy as a therapeutic strategy for glioblastoma. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201701568R. PMID 29856660 DOI: 10.1096/Fj.201701568R  0.417
2018 Shabat D, Gnaim S, Scomparin A, Das S, Satchi-Fainaro R. Real-Time Monitoring of Prodrug Activation by Direct-Mode of Chemiluminescence. Angewandte Chemie (International Ed. in English). PMID 29786931 DOI: 10.1002/Anie.201804816  0.328
2018 Vossen LI, Markovsky E, Eldar-Boock A, Tschiche HR, Wedepohl S, Pisarevsky E, Satchi-Fainaro R, Calderón M. PEGylated dendritic polyglycerol conjugate targeting NCAM-expressing neuroblastoma: Limitations and challenges. Nanomedicine : Nanotechnology, Biology, and Medicine. 14: 1169-1179. PMID 29471169 DOI: 10.1016/J.Nano.2018.02.009  0.78
2018 Eilon-Shaffer T, Roth-Konforti M, Eldar-Boock A, Satchi-Fainaro R, Shabat D. ortho-Chlorination of phenoxy 1,2-dioxetane yields superior chemiluminescent probes for in vitro and in vivo imaging. Organic & Biomolecular Chemistry. PMID 29451576 DOI: 10.1039/C8Ob00087E  0.346
2018 Zupančič E, Curato C, Kim JS, Yeini E, Porat Z, Viana AS, Globerson-Levin A, Waks T, Eshhar Z, Moreira JN, Satchi-Fainaro R, Eisenbach L, Jung S, Florindo HF. Nanoparticulate vaccine inhibits tumor growth via improved T cell recruitment into melanoma and huHER2 breast cancer. Nanomedicine : Nanotechnology, Biology, and Medicine. PMID 29306001 DOI: 10.1016/J.Nano.2017.12.011  0.374
2018 Gibori H, Eliyahu S, Krivitsky A, Ben-Shushan D, Epshtein Y, Tiram G, Blau R, Ofek P, Lee JS, Ruppin E, Landsman L, Barshack I, Golan T, Merquiol E, Blum G, ... Satchi-Fainaro R, et al. Amphiphilic nanocarrier-induced modulation of PLK1 and miR-34a leads to improved therapeutic response in pancreatic cancer. Nature Communications. 9: 16. PMID 29295989 DOI: 10.1038/S41467-017-02283-9  0.38
2017 Krivitsky A, Polyak D, Scomparin A, Eliyahu S, Ofek P, Tiram G, Kalinski H, Avkin-Nachum S, Gracia NF, Albertazzi L, Satchi-Fainaro R. Amphiphilic poly(α)glutamate polymeric micelles for systemic administration of siRNA to tumors. Nanomedicine : Nanotechnology, Biology, and Medicine. PMID 29127036 DOI: 10.1016/J.Nano.2017.10.012  0.444
2017 Ferber S, Tiram G, Sousa-Herves A, Eldar-Boock A, Krivitsky A, Scomparin A, Yeini E, Ofek P, Ben-Shushan D, Vossen LI, Licha K, Grossman R, Ram Z, Henkin J, Ruppin E, ... ... Satchi-Fainaro R, et al. Co-targeting the tumor endothelium and P-selectin-expressing glioblastoma cells leads to a remarkable therapeutic outcome. Elife. 6. PMID 28976305 DOI: 10.7554/Elife.25281  0.452
2017 Scomparin A, Florindo HF, Tiram G, Ferguson EL, Satchi-Fainaro R. Two-step polymer- and liposome- enzyme prodrug therapies for cancer: PDEPT and PELT concepts and future perspectives. Advanced Drug Delivery Reviews. PMID 28916497 DOI: 10.1016/J.Addr.2017.09.011  0.386
2017 Satchi-Fainaro R, Vicent MJ, Richardson S. Professor Ruth Duncan: A Pioneer in the Field of Polymer Therapeutics. Journal of Drug Targeting. 1-3. PMID 28832230 DOI: 10.1080/1061186X.2017.1371722  0.347
2017 Eldar-Boock A, Blau R, Ryppa C, Baabur-Cohen H, Many A, Vicent MJ, Kratz F, Sanchis J, Satchi-Fainaro R. Integrin-Targeted Nano-Sized Polymeric Systems for Paclitaxel Conjugation: A Comparative Study. Journal of Drug Targeting. 1-41. PMID 28737432 DOI: 10.1080/1061186X.2017.1358727  0.468
2017 Markovsky E, Vax E, Ben-Shushan D, Eldar-Boock A, Shukrun R, Yeini E, Barshack I, Caspi R, Harari-Steinberg O, Pode-Shakked N, Dekel B, Satchi-Fainaro R. Wilms Tumor NCAM-Expressing Cancer Stem Cells as Potential Therapeutic Target for Polymeric Nanomedicine. Molecular Cancer Therapeutics. 16: 2462-2472. PMID 28729402 DOI: 10.1158/1535-7163.Mct-17-0184  0.5
2017 Ferguson EL, Scomparin A, Hailu H, Satchi-Fainaro R. HPMA Copolymer-phospholipase C and Dextrin-Phospholipase A2 as Model Triggers for Polymer Enzyme Liposome Therapy (PELT). Journal of Drug Targeting. 1-33. PMID 28728446 DOI: 10.1080/1061186X.2017.1358726  0.357
2017 Ofek P, Tiram G, Satchi-Fainaro R. Angiogenesis regulation by nanocarriers bearing RNA interference. Advanced Drug Delivery Reviews. 119: 3-19. PMID 28163106 DOI: 10.1016/J.Addr.2017.01.008  0.355
2017 Markovsky E, Eldar-Boock A, Ben-Shushan D, Baabur-Cohen H, Yeini E, Pisarevsky E, Many A, Aviel-Ronen S, Barshack I, Satchi-Fainaro R. Targeting NCAM-expressing neuroblastoma with polymeric precision nanomedicine. Journal of Controlled Release : Official Journal of the Controlled Release Society. 249: 162-172. PMID 28159518 DOI: 10.1016/J.Jconrel.2017.01.044  0.784
2017 Ferber S, Tiram G, Sousa-Herves A, Eldar-Boock A, Krivitsky A, Scomparin A, Yeini E, Ofek P, Ben-Shushan D, Vossen LI, Licha K, Grossman R, Ram Z, Henkin J, Ruppin E, ... ... Satchi-Fainaro R, et al. Author response: Co-targeting the tumor endothelium and P-selectin-expressing glioblastoma cells leads to a remarkable therapeutic outcome Elife. DOI: 10.7554/Elife.25281.027  0.416
2016 Alishekevitz D, Gingis-Velitski S, Kaidar-Person O, Gutter-Kapon L, Scherer SD, Raviv Z, Merquiol E, Ben-Nun Y, Miller V, Rachman-Tzemah C, Timaner M, Mumblat Y, Ilan N, Loven D, Hershkovitz D, ... Satchi-Fainaro R, et al. Macrophage-Induced Lymphangiogenesis and Metastasis following Paclitaxel Chemotherapy Is Regulated by VEGFR3. Cell Reports. 17: 1344-1356. PMID 27783948 DOI: 10.1016/J.Celrep.2016.09.083  0.407
2016 Shatsberg Z, Zhang X, Ofek P, Malhotra S, Krivitsky A, Scomparin A, Tiram G, Calderón M, Haag R, Satchi-Fainaro R. Functionalized nanogels carrying an anticancer microRNA for glioblastoma therapy. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 27569663 DOI: 10.1016/J.Jconrel.2016.08.029  0.351
2016 Gnaim S, Scomparin A, Li X, Baran PS, Rader C, Satchi-Fainaro R, Shabat D. Tagging the Untaggable: A Difluoroalkyl-Sulfinate Ketone-Based Reagent for Direct C-H Functionalization of Bioactive Heteroarenes. Bioconjugate Chemistry. PMID 27494153 DOI: 10.1021/Acs.Bioconjchem.6B00382  0.327
2016 Blau R, Krivitsky A, Epshtein Y, Satchi-Fainaro R. Are nanotheranostics and nanodiagnostics-guided drug delivery stepping stones towards precision medicine? Drug Resistance Updates : Reviews and Commentaries in Antimicrobial and Anticancer Chemotherapy. 27: 39-58. PMID 27449597 DOI: 10.1016/J.Drup.2016.06.003  0.355
2016 Krivitsky A, Polyak D, Scomparin A, Eliyahu S, Ori A, Avkin Nachum S, Krivitsky V, Satchi-Fainaro R. Structure-function correlation of aminated poly(α)glutamate as siRNA nanocarriers. Biomacromolecules. PMID 27377188 DOI: 10.1021/Acs.Biomac.6B00555  0.376
2016 Baabur-Cohen H, Vossen L, Krüger HR, Eldar-Boock A, Yeini E, Landa-Rouben N, Tiram G, Wedepohl S, Markovsky E, Leor J, Calderón M, Satchi-Fainaro R. In vivo comparative study of distinct polymeric architectures bearing a combination of paclitaxel and doxorubicin at a synergistic ratio. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 27374630 DOI: 10.1016/J.Jconrel.2016.06.037  0.469
2016 Polyak D, Krivitsky A, Scomparin A, Eliyahu S, Kalinski H, Avkin-Nachum S, Satchi-Fainaro R. Systemic delivery of siRNA by aminated poly(α)glutamate for the treatment of solid tumors. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 27356019 DOI: 10.1016/J.Jconrel.2016.06.034  0.499
2016 Ofek P, Calderón M, Mehrabadi FS, Krivitsky A, Ferber S, Tiram G, Yerushalmi N, Kredo-Russo S, Grossman R, Ram Z, Haag R, Satchi-Fainaro R. Restoring the Oncosuppressor Activity of MicroRNA-34a in Glioblastoma Using a Polyglycerol-based Polyplex. Nanomedicine : Nanotechnology, Biology, and Medicine. PMID 27262933 DOI: 10.1016/J.Nano.2016.05.016  0.346
2016 Schwartz H, Blacher E, Amer M, Livneh N, Abramovitz L, Klein A, Ben-Shushan D, Soffer S, Blazquez R, Barrantes-Freer A, Müller M, Müller-Decker K, Stein R, Tsarfaty G, Satchi-Fainaro R, et al. Incipient melanoma brain metastases instigate astrogliosis and neuroinflammation. Cancer Research. PMID 27261506 DOI: 10.1158/0008-5472.Can-16-0485  0.307
2016 Golan M, Feinshtein V, Polyak D, Scomparin A, Satchi-Fainaro R, David A. Inhibition of Gene Expression and Cancer Cell Migration by CD44v3/6-Targeted Polyion Complexes. Bioconjugate Chemistry. 27: 947-60. PMID 26974863 DOI: 10.1021/Acs.Bioconjchem.6B00020  0.478
2016 Tiram G, Segal E, Krivitsky A, Shreberk-Hassidim R, Ofek P, Ferber S, Udagawa T, Edry L, Shomron N, Roniger M, Kerem B, Shaked Y, Aviel-Ronen S, Barshack I, Calderon M, ... ... Satchi-Fainaro R, et al. Identification of Dormancy-Associated MicroRNAs for the Design of Osteosarcoma-Targeted Dendritic Polyglycerol Nanopolyplexes. Acs Nano. PMID 26815014 DOI: 10.1021/Acsnano.5B06189  0.415
2016 Ofek P, Dromi N, Yerushalmi N, Kredo-Russo S, Grossman R, Ram Z, Satchi-Fainaro R. Abstract B05: Patient-derived GBM tumors versus patient-derived primary cells and GBM cell lines: lessons from microRNA profiling Clinical Cancer Research. 22. DOI: 10.1158/1557-3265.Pdx16-B05  0.379
2016 Schwartz H, Blacher E, Amer M, Livneh N, Klein A, Ben-Shushan D, Soffer S, Stein R, Satchi-Fainaro R, Umansky V, Pukrop T, Erez N. Abstract C26: Melanoma brain metastasis is facilitated by instigation of reactive astrogliosis Cancer Research. 76. DOI: 10.1158/1538-7445.Tme16-C26  0.343
2016 Tiram G, Ofek P, Udagawa T, Shomron N, Roniger M, Kerem B, Shaked Y, Aviel-Ronen S, Barshack I, Calderon M, Haag R, Satchi-Fainaro R. Abstract B42: Dysregulation of key microRNAs controlling tumor-host interactions triggers escape from osteosarcoma dormancy Cancer Research. 76. DOI: 10.1158/1538-7445.Tme16-B42  0.377
2016 Tiram G, Ferber S, Satchi-Fainaro R. Abstract B39: Identifying molecular signatures of tumor dormancy as a basis for the rational design of precision nanomedicines Cancer Research. 76. DOI: 10.1158/1538-7445.Tme16-B39  0.474
2015 Scomparin A, Polyak D, Krivitsky A, Satchi-Fainaro R. Achieving successful delivery of oligonucleotides--From physico-chemical characterization to in vivo evaluation. Biotechnology Advances. 33: 1294-309. PMID 25916823 DOI: 10.1016/J.Biotechadv.2015.04.008  0.388
2015 Scomparin A, Salmaso S, Eldar-Boock A, Ben-Shushan D, Ferber S, Tiram G, Shmeeda H, Landa-Rouben N, Leor J, Caliceti P, Gabizon A, Satchi-Fainaro R. A comparative study of folate receptor-targeted doxorubicin delivery systems: dosing regimens and therapeutic index. Journal of Controlled Release : Official Journal of the Controlled Release Society. 208: 106-20. PMID 25869964 DOI: 10.1016/J.Jconrel.2015.04.009  0.453
2015 Bonzi G, Salmaso S, Scomparin A, Eldar-Boock A, Satchi-Fainaro R, Caliceti P. Novel pullulan bioconjugate for selective breast cancer bone metastases treatment. Bioconjugate Chemistry. 26: 489-501. PMID 25613006 DOI: 10.1021/Bc500614B  0.31
2014 Ben-Shushan D, Markovsky E, Gibori H, Tiram G, Scomparin A, Satchi-Fainaro R. Overcoming obstacles in microRNA delivery towards improved cancer therapy. Drug Delivery and Translational Research. 4: 38-49. PMID 25786616 DOI: 10.1007/S13346-013-0160-0  0.302
2014 Ferber S, Tiram G, Satchi-Fainaro R. Monitoring functionality and morphology of vasculature recruited by factors secreted by fast-growing tumor-generating cells. Journal of Visualized Experiments : Jove. e51525. PMID 25490071 DOI: 10.3791/51525  0.366
2014 Markovsky E, Baabur-Cohen H, Satchi-Fainaro R. Anticancer polymeric nanomedicine bearing synergistic drug combination is superior to a mixture of individually-conjugated drugs. Journal of Controlled Release : Official Journal of the Controlled Release Society. 187: 145-57. PMID 24862318 DOI: 10.1016/J.Jconrel.2014.05.025  0.438
2014 Kisin-Finfer E, Ferber S, Blau R, Satchi-Fainaro R, Shabat D. Synthesis and evaluation of new NIR-fluorescent probes for cathepsin B: ICT versus FRET as a turn-ON mode-of-action. Bioorganic & Medicinal Chemistry Letters. 24: 2453-8. PMID 24767838 DOI: 10.1016/J.Bmcl.2014.04.022  0.331
2014 Tiram G, Scomparin A, Ofek P, Satchi-Fainaro R. Interfering cancer with polymeric siRNA nanomedicines. Journal of Biomedical Nanotechnology. 10: 50-66. PMID 24724498 DOI: 10.1166/Jbn.2014.1715  0.413
2014 Ferber S, Baabur-Cohen H, Blau R, Epshtein Y, Kisin-Finfer E, Redy O, Shabat D, Satchi-Fainaro R. Polymeric nanotheranostics for real-time non-invasive optical imaging of breast cancer progression and drug release. Cancer Letters. 352: 81-9. PMID 24614283 DOI: 10.1016/J.Canlet.2014.02.022  0.401
2014 Eldar-Boock A, Ben-Shushan D, Sanchis J, Lupu R, Vicent MJ, Satchi-Fainaro R. Abstract LB-196: Preventing breast cancer metastases with an anti-angiogenic and anticancer RGD-bearing nanomedicine Cancer Research. 74. DOI: 10.1158/1538-7445.Am2014-Lb-196  0.462
2014 Ferber S, Tiram G, Amsalem O, Yavin E, Almog N, Henkin J, Calderon M, Haag R, Satchi-Fainaro R. Abstract LB-104: Reverting the angiogenic switch of glioblastoma with a nanopolyplex based on the molecular fingerprint of tumor dormancy Cancer Research. 74. DOI: 10.1158/1538-7445.Am2014-Lb-104  0.448
2014 Ofek P, Calderon M, Sheikhi-Mehrabadi F, Ferber S, Haag R, Satchi-Fainaro R. Abstract 4391: Multi-modal nanomedicine for glioblastoma Cancer Research. 74: 4391-4391. DOI: 10.1158/1538-7445.Am2014-4391  0.38
2014 Tiram G, Ferber S, Ofek P, Shomron N, Udagawa T, Aviel-Ronen S, Barshack I, Satchi-Fainaro R. Abstract 4219: miR-34a, miR-93 and miR-200c - novel molecular regulators of osteosarcoma dormancy Cancer Research. 74: 4219-4219. DOI: 10.1158/1538-7445.Am2014-4219  0.333
2013 Eldar-Boock A, Polyak D, Scomparin A, Satchi-Fainaro R. Nano-sized polymers and liposomes designed to deliver combination therapy for cancer. Current Opinion in Biotechnology. 24: 682-9. PMID 23726153 DOI: 10.1016/J.Copbio.2013.04.014  0.43
2013 Miller K, Clementi C, Polyak D, Eldar-Boock A, Benayoun L, Barshack I, Shaked Y, Pasut G, Satchi-Fainaro R. Poly(ethylene glycol)-paclitaxel-alendronate self-assembled micelles for the targeted treatment of breast cancer bone metastases. Biomaterials. 34: 3795-806. PMID 23434349 DOI: 10.1016/J.Biomaterials.2013.01.052  0.407
2013 Benayoun L, Schaffer M, Bril R, Gingis-Velitski S, Segal E, Nevelsky A, Satchi-Fainaro R, Shaked Y. Porfimer-sodium (Photofrin-II) in combination with ionizing radiation inhibits tumor-initiating cell proliferation and improves glioblastoma treatment efficacy Cancer Biology and Therapy. 14: 64-74. PMID 23114641 DOI: 10.4161/Cbt.22630  0.429
2013 Herzog IM, Feldman M, Eldar-Boock A, Satchi-Fainaro R, Fridman M. Design of membrane targeting tobramycin-based cationic amphiphiles with reduced hemolytic activity Medchemcomm. 4: 120-124. DOI: 10.1039/C2Md20162C  0.347
2013 Polyak D, Eldar-Boock A, Baabur-Cohen H, Satchi-Fainaro R. Polymer conjugates for focal and targeted delivery of drugs Polymers For Advanced Technologies. 24: 777-790. DOI: 10.1002/Pat.3158  0.469
2012 Satchi-Fainaro R, Ferber S, Segal E, Ma L, Dixit N, Ijaz A, Hlatky L, Abdollahi A, Almog N. Prospective identification of glioblastoma cells generating dormant tumors. Plos One. 7: e44395. PMID 22970208 DOI: 10.1371/Journal.Pone.0044395  0.432
2012 Benayoun L, Gingis-Velitski S, Voloshin T, Segal E, Segev R, Munster M, Bril R, Satchi-Fainaro R, Scherer SJ, Shaked Y. Tumor-initiating cells of various tumor types exhibit differential angiogenic properties and react differently to antiangiogenic drugs. Stem Cells (Dayton, Ohio). 30: 1831-41. PMID 22782858 DOI: 10.1002/Stem.1170  0.449
2012 Markovsky E, Baabur-Cohen H, Eldar-Boock A, Omer L, Tiram G, Ferber S, Ofek P, Polyak D, Scomparin A, Satchi-Fainaro R. Administration, distribution, metabolism and elimination of polymer therapeutics. Journal of Controlled Release : Official Journal of the Controlled Release Society. 161: 446-60. PMID 22286005 DOI: 10.1016/J.Jconrel.2011.12.021  0.364
2012 Ofek P, Fischer W, Calderon M, Haag R, Satchi-Fainaro R. Abstract 5650: Targeting siRNA to tumors and their stroma as a dual anticancer and anti-angiogenic therapy Cancer Research. 72: 5650-5650. DOI: 10.1158/1538-7445.Am2012-5650  0.441
2012 Ferber S, Segal E, Almog N, Satchi-Fainaro R. Abstract 5238: Impaired angiogenesis as a hallmark of prolonged tumor dormancy in a mouse model of human glioblastoma Cancer Research. 72: 5238-5238. DOI: 10.1158/1538-7445.Am2012-5238  0.376
2012 Tiram G, Segal E, Sherberk R, Bachar G, Ofek P, Udagawa T, Edry L, Shomron N, Satchi-Fainaro R. Abstract 5235: Uncovering tumor-host molecular and cellular interactions involved in tumor dormancy using microRNAs Cancer Research. 72: 5235-5235. DOI: 10.1158/1538-7445.Am2012-5235  0.398
2012 Eldar-Boock A, Sanchis J, Lupu R, Vicent MJ, Satchi-Fainaro R. Abstract 5225: Correlation between αvβ3 integrin expression, paclitaxel resistance and RGD-bearing conjugate efficacy Cancer Research. 72: 5225-5225. DOI: 10.1158/1538-7445.Am2012-5225  0.505
2012 Tiram G, Segal E, Bachar G, Shreberk R, Ofek P, Satchi-Fainaro R. Abstract 4643: Shedding light on the molecular basis of tumor dormancy using antiangiogenic nanomedicines Cancer Research. 72: 4643-4643. DOI: 10.1158/1538-7445.Am2012-4643  0.362
2011 Karton-Lifshin N, Segal E, Omer L, Portnoy M, Satchi-Fainaro R, Shabat D. A unique paradigm for a Turn-ON near-infrared cyanine-based probe: noninvasive intravital optical imaging of hydrogen peroxide. Journal of the American Chemical Society. 133: 10960-5. PMID 21631116 DOI: 10.1021/Ja203145V  0.301
2011 Clementi C, Miller K, Mero A, Satchi-Fainaro R, Pasut G. Dendritic poly(ethylene glycol) bearing paclitaxel and alendronate for targeting bone neoplasms. Molecular Pharmaceutics. 8: 1063-72. PMID 21608527 DOI: 10.1021/Mp2001445  0.424
2011 Miller K, Eldar-Boock A, Polyak D, Segal E, Benayoun L, Shaked Y, Satchi-Fainaro R. Antiangiogenic antitumor activity of HPMA copolymer-paclitaxel-alendronate conjugate on breast cancer bone metastasis mouse model. Molecular Pharmaceutics. 8: 1052-62. PMID 21545170 DOI: 10.1021/Mp200083N  0.483
2011 Segal E, Pan H, Benayoun L, Kopečková P, Shaked Y, Kopeček J, Satchi-Fainaro R. Enhanced anti-tumor activity and safety profile of targeted nano-scaled HPMA copolymer-alendronate-TNP-470 conjugate in the treatment of bone malignances. Biomaterials. 32: 4450-63. PMID 21429572 DOI: 10.1016/J.Biomaterials.2011.02.059  0.436
2011 Eldar-Boock A, Miller K, Sanchis J, Lupu R, Vicent MJ, Satchi-Fainaro R. Integrin-assisted drug delivery of nano-scaled polymer therapeutics bearing paclitaxel Biomaterials. 32: 3862-3874. PMID 21376390 DOI: 10.1016/J.Biomaterials.2011.01.073  0.51
2011 Scomparin A, Salmaso S, Bersani S, Satchi-Fainaro R, Caliceti P. Novel folated and non-folated pullulan bioconjugates for anticancer drug delivery. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 42: 547-58. PMID 21371555 DOI: 10.1016/J.Ejps.2011.02.012  0.383
2011 Polyak D, Ryppa C, Eldar-Boock A, Ofek P, Many A, Licha K, Kratz F, Satchi-Fainaro R. Development of PEGylated doxorubicin-E-[c(RGDfK)2] conjugate for integrin-targeted cancer therapy Polymers For Advanced Technologies. 22: 103-113. DOI: 10.1002/Pat.1731  0.456
2010 Marom H, Miller K, Bechor-Bar Y, Tsarfaty G, Satchi-Fainaro R, Gozin M. Toward development of targeted nonsteroidal antiandrogen-1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid-gadolinium complex for prostate cancer diagnostics. Journal of Medicinal Chemistry. 53: 6316-25. PMID 20715870 DOI: 10.1021/Jm100289B  0.316
2010 Ofek P, Fischer W, Calderón M, Haag R, Satchi-Fainaro R. In vivo delivery of small interfering RNA to tumors and their vasculature by novel dendritic nanocarriers The Faseb Journal. 24: 3122-3134. PMID 20385622 DOI: 10.1096/Fj.09-149641  0.448
2009 Segal E, Satchi-Fainaro R. Design and development of polymer conjugates as anti-angiogenic agents. Advanced Drug Delivery Reviews. 61: 1159-76. PMID 19699248 DOI: 10.1016/J.Addr.2009.06.005  0.483
2009 Erez R, Segal E, Miller K, Satchi-Fainaro R, Shabat D. Enhanced cytotoxicity of a polymer-drug conjugate with triple payload of paclitaxel. Bioorganic & Medicinal Chemistry. 17: 4327-35. PMID 19482477 DOI: 10.1016/J.Bmc.2009.05.028  0.41
2009 Segal E, Pan H, Ofek P, Udagawa T, Kopecková P, Kopecek J, Satchi-Fainaro R. Targeting angiogenesis-dependent calcified neoplasms using combined polymer therapeutics. Plos One. 4: e5233. PMID 19381291 DOI: 10.1371/Journal.Pone.0005233  0.463
2009 Miller K, Erez R, Segal E, Shabat D, Satchi-Fainaro R. Targeting bone metastases with a bispecific anticancer and antiangiogenic polymer-alendronate-taxane conjugate. Angewandte Chemie (International Ed. in English). 48: 2949-54. PMID 19294707 DOI: 10.1002/Anie.200805133  0.38
2009 Stern L, Perry R, Ofek P, Many A, Shabat D, Satchi-Fainaro R. A novel antitumor prodrug platform designed to be cleaved by the endoprotease legumain. Bioconjugate Chemistry. 20: 500-10. PMID 19196156 DOI: 10.1021/Bc800448U  0.434
2009 Ryppa C, Mann-Steinberg H, Biniossek ML, Satchi-Fainaro R, Kratz F. In vitro and in vivo evaluation of a paclitaxel conjugate with the divalent peptide E-[c(RGDfK)2] that targets integrin alpha v beta 3. International Journal of Pharmaceutics. 368: 89-97. PMID 18992308 DOI: 10.1016/J.Ijpharm.2008.09.055  0.345
2007 Chesler L, Goldenberg DD, Seales IT, Satchi-Fainaro R, Grimmer M, Collins R, Struett C, Nguyen KN, Kim G, Tihan T, Bao Y, Brekken RA, Bergers G, Folkman J, Weiss WA. Malignant progression and blockade of angiogenesis in a murine transgenic model of neuroblastoma. Cancer Research. 67: 9435-42. PMID 17909053 DOI: 10.1158/0008-5472.Can-07-1316  0.439
2007 Nahari D, Satchi-Fainaro R, Chen M, Mitchell I, Task LB, Liu Z, Kihneman J, Carroll AB, Terada LS, Nwariaku FE. Tumor cytotoxicity and endothelial Rac inhibition induced by TNP-470 in anaplastic thyroid cancer. Molecular Cancer Therapeutics. 6: 1329-37. PMID 17431111 DOI: 10.1158/1535-7163.Mct-06-0554  0.383
2007 Sagi A, Segal E, Satchi-Fainaro R, Shabat D. Remarkable drug-release enhancement with an elimination-based AB3 self-immolative dendritic amplifier. Bioorganic & Medicinal Chemistry. 15: 3720-7. PMID 17416532 DOI: 10.1016/J.Bmc.2007.03.054  0.355
2006 Duncan R, Ringsdorf H, Satchi-Fainaro R. Polymer therapeutics--polymers as drugs, drug and protein conjugates and gene delivery systems: past, present and future opportunities. Journal of Drug Targeting. 14: 337-41. PMID 17092834 DOI: 10.1080/10611860600833856  0.316
2006 Becker CM, Wright RD, Satchi-Fainaro R, Funakoshi T, Folkman J, Kung AL, D'Amato RJ. A novel noninvasive model of endometriosis for monitoring the efficacy of antiangiogenic therapy. The American Journal of Pathology. 168: 2074-84. PMID 16723720 DOI: 10.2353/Ajpath.2006.051133  0.303
2005 Sjin RMTT, Satchi-Fainaro R, Birsner AE, Ramanujam VMS, Folkman J, Javaherian K. A 27-amino-acid synthetic peptide corresponding to the NH 2-terminal zinc-binding domain of endostatin is responsible for its antitumor activity Cancer Research. 65: 3656-3663. PMID 15867360 DOI: 10.1158/0008-5472.Can-04-1833  0.317
2005 Satchi-Fainaro R, Mamluk R, Wang L, Short SM, Nagy JA, Feng D, Dvorak AM, Dvorak HF, Puder M, Mukhopadhyay D, Folkman J. Inhibition of vessel permeability by TNP-470 and its polymer conjugate, caplostatin. Cancer Cell. 7: 251-61. PMID 15766663 DOI: 10.1016/J.Ccr.2005.02.007  0.385
2004 Satchi-Fainaro R, Puder M, Davies JW, Tran HT, Sampson DA, Greene AK, Corfas G, Folkman J. Targeting angiogenesis with a conjugate of HPMA copolymer and TNP-470. Nature Medicine. 10: 255-61. PMID 14981512 DOI: 10.1038/Nm1002  0.516
2003 Satchi-Fainaro R, Hailu H, Davies JW, Summerford C, Duncan R. PDEPT: Polymer-directed enzyme prodrug therapy. 2. HPMA copolymer-β-lactamase and HPMA copolymer-C-Dox as a model combination Bioconjugate Chemistry. 14: 797-804. PMID 12862433 DOI: 10.1021/Bc020091K  0.354
2002 Satchi-Fainaro R. Targeting tumor vasculature: reality or a dream? Journal of Drug Targeting. 10: 529-533. PMID 12683719 DOI: 10.1080/1061186021000051062  0.506
2002 Satchi-Fainaro R, Wrasidlo W, Lode HN, Shabat D. Synthesis and characterization of a catalytic antibody-HPMA copolymer-Conjugate as a tool for tumor selective prodrug activation. Bioorganic & Medicinal Chemistry. 10: 3023-9. PMID 12110325 DOI: 10.1016/S0968-0896(02)00156-6  0.359
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