Alan Sher - Publications

Affiliations: 
LPD NIAID, NIH, Rockville, MD, United States 

348 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Hilligan KL, Namasivayam S, Clancy CS, Baker PJ, Old SI, Peluf V, Amaral EP, Oland SD, O'Mard D, Laux J, Cohen M, Garza NL, Lafont BAP, Johnson RF, Feng CG, ... ... Sher A, et al. Bacterial-induced or passively administered interferon gamma conditions the lung for early control of SARS-CoV-2. Nature Communications. 14: 8229. PMID 38086794 DOI: 10.1038/s41467-023-43447-0  0.356
2023 Amaral EP, Namasivayam S, Queiroz ATL, Fukutani E, Hilligan KL, Aberman K, Fisher L, Bomfim CCB, Kauffman K, Buchanan J, Santuo L, Gazzinelli-Guimaraes PH, Costa DL, Teixeira MA, Barreto-Duarte B, ... ... Sher A, et al. BACH1 promotes tissue necrosis and Mycobacterium tuberculosis susceptibility. Nature Microbiology. PMID 38066332 DOI: 10.1038/s41564-023-01523-7  0.347
2023 Iwamura C, Ohnuki H, Flomerfelt FA, Zheng L, Carletti A, Wakashin H, Mikami Y, Brooks SR, Kanno Y, Gress RE, Tosato G, Nakayama T, O'Shea JJ, Sher A, Jankovic D. Microbial ligand-independent regulation of lymphopoiesis by NOD1. Nature Immunology. PMID 37957354 DOI: 10.1038/s41590-023-01668-x  0.339
2023 Oyesola OO, Hilligan KL, Namasivayam S, Howard N, Clancy CS, Zhao M, Oland SD, Kiwanuka KN, Garza NL, Lafont BAP, Johnson RF, Mayer-Barber KD, Sher A, Loke P. Exposure to lung-migrating helminth protects against murine SARS-CoV-2 infection through macrophage-dependent T cell activation. Science Immunology. 8: eadf8161. PMID 37566678 DOI: 10.1126/sciimmunol.adf8161  0.31
2022 Hilligan KL, Oyesola OO, Namasivayam S, Howard N, Clancy CS, Oland SD, Garza NL, Lafont BAP, Johnson RF, Mayer-Barber KD, Sher A, Loke PN. Helminth exposure protects against murine SARS-CoV-2 infection through macrophage dependent T cell activation. Biorxiv : the Preprint Server For Biology. PMID 36380767 DOI: 10.1101/2022.11.09.515832  0.327
2022 Amaral EP, Foreman TW, Namasivayam S, Hilligan KL, Kauffman KD, Barbosa Bomfim CC, Costa DL, Barreto-Duarte B, Gurgel-Rocha C, Santana MF, Cordeiro-Santos M, Du Bruyn E, Riou C, Aberman K, Wilkinson RJ, ... ... Sher A, et al. GPX4 regulates cellular necrosis and host resistance in Mycobacterium tuberculosis infection. The Journal of Experimental Medicine. 219. PMID 36069923 DOI: 10.1084/jem.20220504  0.346
2022 Bohrer AC, Castro E, Tocheny CE, Assmann M, Schwarz B, Bohrnsen E, Makiya MA, Legrand F, Hilligan KL, Baker PJ, Torres-Juarez F, Hu Z, Ma H, Wang L, Niu L, ... ... Sher A, et al. Rapid GPR183-mediated recruitment of eosinophils to the lung after Mycobacterium tuberculosis infection. Cell Reports. 40: 111144. PMID 35905725 DOI: 10.1016/j.celrep.2022.111144  0.318
2022 Wallis RS, O'Garra A, Sher A, Wack A. Host-directed immunotherapy of viral and bacterial infections: past, present and future. Nature Reviews. Immunology. PMID 35672482 DOI: 10.1038/s41577-022-00734-z  0.301
2022 Fang D, Cui K, Cao Y, Zheng M, Kawabe T, Hu G, Khillan JS, Li D, Zhong C, Jankovic D, Sher A, Zhao K, Zhu J. Differential regulation of transcription factor T-bet induction during NK cell development and T helper-1 cell differentiation. Immunity. PMID 35381213 DOI: 10.1016/j.immuni.2022.03.005  0.313
2022 Nelson CE, Namasivayam S, Foreman TW, Kauffman KD, Sakai S, Dorosky DE, Lora NE, Brooks K, Potter EL, Garza NL, Lafont BAP, Johnson RF, Roederer M, Sher A, Weiskopf D, et al. Mild SARS-CoV-2 infection in rhesus macaques is associated with viral control prior to antigen-specific T cell responses in tissues. Science Immunology. eabo0535. PMID 35271298 DOI: 10.1126/sciimmunol.abo0535  0.318
2022 Martin-Fernandez M, Buta S, Le Voyer T, Li Z, Dynesen LT, Vuillier F, Franklin L, Ailal F, Muglia Amancio A, Malle L, Gruber C, Benhsaien I, Altman J, Taft J, Deswarte C, ... ... Sher A, et al. A partial form of inherited human USP18 deficiency underlies infection and inflammation. The Journal of Experimental Medicine. 219. PMID 35258551 DOI: 10.1084/jem.20211273  0.335
2022 Hilligan KL, Namasivayam S, Clancy CS, O'Mard D, Oland SD, Robertson SJ, Baker PJ, Castro E, Garza NL, Lafont BAP, Johnson R, Ronchese F, Mayer-Barber KD, Best SM, Sher A. Intravenous administration of BCG protects mice against lethal SARS-CoV-2 challenge. The Journal of Experimental Medicine. 219. PMID 34889942 DOI: 10.1084/jem.20211862  0.334
2021 Hilligan KL, Namasivayam S, Clancy CS, O'Mard D, Oland SD, Robertson SJ, Baker PJ, Castro E, Garza NL, Lafont BAP, Johnson R, Ronchese F, Mayer-Barber KD, Best SM, Sher A. Intravenous administration of BCG protects mice against lethal SARS-CoV-2 challenge. Biorxiv : the Preprint Server For Biology. PMID 34494021 DOI: 10.1101/2021.08.30.458273  0.354
2021 Costa DL, Amaral EP, Namasivayam S, Mittereder LR, Andrade BB, Sher A. Enhancement of CD4 T Cell Function as a Strategy for Improving Antibiotic Therapy Efficacy in Tuberculosis: Does It Work? Frontiers in Cellular and Infection Microbiology. 11: 672527. PMID 34235093 DOI: 10.3389/fcimb.2021.672527  0.327
2020 Costa DL, Amaral EP, Andrade BB, Sher A. Modulation of Inflammation and Immune Responses by Heme Oxygenase-1: Implications for Infection with Intracellular Pathogens. Antioxidants (Basel, Switzerland). 9. PMID 33266044 DOI: 10.3390/antiox9121205  0.304
2020 Hilligan KL, Tang SC, Hyde EJ, Roussel E, Mayer JU, Yang J, Wakelin KA, Schmidt AJ, Connor LM, Sher A, MacDonald AS, Ronchese F. Dermal IRF4+ dendritic cells and monocytes license CD4+ T helper cells to distinct cytokine profiles. Nature Communications. 11: 5637. PMID 33159073 DOI: 10.1038/s41467-020-19463-9  0.347
2020 Costa DL, Amaral EP, Namasivayam S, Mittereder LR, Fisher L, Bonfim CC, Sardinha-Silva A, Thompson RW, Hieny SE, Andrade BB, Sher A. Heme oxygenase-1 inhibition promotes IFNγ- and NOS2-mediated control of Mycobacterium tuberculosis infection. Mucosal Immunology. PMID 32862202 DOI: 10.1038/S41385-020-00342-X  0.406
2020 Du Bruyn E, Ruzive S, Lindestam Arlehamn CS, Sette A, Sher A, Barber DL, Wilkinson RJ, Riou C. Mycobacterium tuberculosis-specific CD4 T cells expressing CD153 inversely associate with bacterial load and disease severity in human tuberculosis. Mucosal Immunology. PMID 32678272 DOI: 10.1038/S41385-020-0322-6  0.37
2020 Kawabe T, Yi J, Kawajiri A, Hilligan K, Fang D, Ishii N, Yamane H, Zhu J, Jankovic D, Kim KS, Trinchieri G, Sher A. Requirements for the differentiation of innate T-bet memory-phenotype CD4 T lymphocytes under steady state. Nature Communications. 11: 3366. PMID 32632165 DOI: 10.1038/S41467-020-17136-1  0.396
2020 Marino AP, Dos Santos LI, Henriques PM, Roffe E, Vasconcelos-Santos DV, Sher A, Jankovic D, Gomes MS, Amaral LR, Campi-Azevedo AC, Teixeira-Carvalho A, Martins-Filho OA, Gazzinelli RT, Antonelli LR. Circulating inflammatory mediators as biomarkers of ocular toxoplasmosis in acute and in chronic infection. Journal of Leukocyte Biology. 108: 1253-1264. PMID 32421913 DOI: 10.1002/Jlb.4Ma0420-702R  0.426
2020 Namasivayam S, Diarra B, Diabate S, Sarro YDS, Kone A, Kone B, Tolofoudie M, Baya B, Diakite MT, Kodio O, Cohen K, Holl J, Achenbach CJ, Chatterjee S, Murphy RL, ... ... Sher A, et al. Patients infected with Mycobacterium africanum versus Mycobacterium tuberculosis possess distinct intestinal microbiota. Plos Neglected Tropical Diseases. 14: e0008230. PMID 32401750 DOI: 10.1371/Journal.Pntd.0008230  0.378
2020 Moreira-Teixeira L, Tabone O, Graham CM, Singhania A, Stavropoulos E, Redford PS, Chakravarty P, Priestnall SL, Suarez-Bonnet A, Herbert E, Mayer-Barber KD, Sher A, Fonseca KL, Sousa J, Cá B, et al. Mouse transcriptome reveals potential signatures of protection and pathogenesis in human tuberculosis. Nature Immunology. 21: 464-476. PMID 32205882 DOI: 10.1038/S41590-020-0610-Z  0.448
2019 Stifter SA, Bhattacharyya N, Sawyer AJ, Cootes TA, Stambas J, Doyle SE, Feigenbaum L, Paul WE, Britton WJ, Sher A, Feng CG. Visualizing the Selectivity and Dynamics of Interferon Signaling In Vivo. Cell Reports. 29: 3539-3550.e4. PMID 31825834 DOI: 10.1016/J.Celrep.2019.11.021  0.428
2019 Petermann F, Pękowska A, Johnson CA, Jankovic D, Shih HY, Jiang K, Hudson WH, Brooks SR, Sun HW, Villarino AV, Yao C, Singleton K, Akondy RS, Kanno Y, Sher A, et al. The Magnitude of IFN-γ Responses Is Fine-Tuned by DNA Architecture and the Non-coding Transcript of Ifng-as1. Molecular Cell. PMID 31377117 DOI: 10.1016/J.Molcel.2019.06.025  0.367
2019 Singhania A, Graham CM, Gabryšová L, Moreira-Teixeira L, Stavropoulos E, Pitt JM, Chakravarty P, Warnatsch A, Branchett WJ, Conejero L, Lin JW, Davidson S, Wilson MS, Bancroft G, Langhorne J, ... ... Sher A, et al. Transcriptional profiling unveils type I and II interferon networks in blood and tissues across diseases. Nature Communications. 10: 2887. PMID 31253760 DOI: 10.1038/S41467-019-10601-6  0.471
2019 Sardinha-Silva A, Mendonça-Natividade FC, Pinzan CF, Lopes CD, Costa DL, Jacot D, Fernandes FF, Zorzetto-Fernandes ALV, Gay NJ, Sher A, Jankovic D, Soldati-Favre D, Grigg ME, Roque-Barreira MC. The lectin-specific activity of Toxoplasma gondii microneme proteins 1 and 4 binds Toll-like receptor 2 and 4 N-glycans to regulate innate immune priming. Plos Pathogens. 15: e1007871. PMID 31226171 DOI: 10.1371/journal.ppat.1007871  0.42
2019 Namasivayam S, Kauffman KD, McCulloch JA, Yuan W, Thovarai V, Mittereder LR, Trinchieri G, Barber DL, Sher A. Correlation between Disease Severity and the Intestinal Microbiome in Mycobacterium tuberculosis-Infected Rhesus Macaques. Mbio. 10. PMID 31164469 DOI: 10.1128/Mbio.01018-19  0.386
2019 Oliveira-de-Souza D, Vinhaes CL, Arriaga MB, Kumar NP, Cubillos-Angulo JM, Shi R, Wei W, Yuan X, Zhang G, Cai Y, Barry CE, Via LE, Sher A, Babu S, Mayer-Barber KD, et al. Molecular degree of perturbation of plasma inflammatory markers associated with tuberculosis reveals distinct disease profiles between Indian and Chinese populations. Scientific Reports. 9: 8002. PMID 31142816 DOI: 10.1038/S41598-019-44513-8  0.327
2019 Amaral EP, Costa DL, Namasivayam S, Riteau N, Kamenyeva O, Mittereder L, Mayer-Barber KD, Andrade BB, Sher A. A major role for ferroptosis in -induced cell death and tissue necrosis. The Journal of Experimental Medicine. PMID 30787033 DOI: 10.1084/Jem.20181776  0.414
2019 Silveira-Mattos PS, Narendran G, Akrami K, Fukutani KF, Anbalagan S, Nayak K, Subramanyam S, Subramani R, Vinhaes CL, Souza DO, Antonelli LR, Satagopan K, Porter BO, Sher A, Swaminathan S, et al. Differential expression of CXCR3 and CCR6 on CD4 T-lymphocytes with distinct memory phenotypes characterizes tuberculosis-associated immune reconstitution inflammatory syndrome. Scientific Reports. 9: 1502. PMID 30728405 DOI: 10.1038/S41598-018-37846-3  0.396
2018 Sallin MA, Kauffman KD, Riou C, Du Bruyn E, Foreman TW, Sakai S, Hoft SG, Myers TG, Gardina PJ, Sher A, Moore R, Wilder-Kofie T, Moore IN, Sette A, Lindestam Arlehamn CS, et al. Host resistance to pulmonary Mycobacterium tuberculosis infection requires CD153 expression. Nature Microbiology. PMID 30202016 DOI: 10.1038/S41564-018-0231-6  0.414
2018 Amaral EP, Riteau N, Moayeri M, Maier N, Mayer-Barber KD, Pereira RM, Lage SL, Kubler A, Bishai WR, D'Império-Lima MR, Sher A, Andrade BB. Lysosomal Cathepsin Release Is Required for NLRP3-Inflammasome Activation by in Infected Macrophages. Frontiers in Immunology. 9: 1427. PMID 29977244 DOI: 10.3389/Fimmu.2018.01427  0.44
2018 Moreira-Teixeira L, Mayer-Barber K, Sher A, O'Garra A. Type I interferons in tuberculosis: Foe and occasionally friend. The Journal of Experimental Medicine. PMID 29666166 DOI: 10.1084/jem.20180325  0.331
2018 Kawabe T, Zhu J, Sher A. Foreign antigen-independent memory-phenotype CD4T cells: a new player in innate immunity? Nature Reviews. Immunology. 18: 1. PMID 29480287 DOI: 10.1038/Nri.2018.12  0.355
2017 Wipperman MF, Fitzgerald DW, Juste MAJ, Taur Y, Namasivayam S, Sher A, Bean JM, Bucci V, Glickman MS. Antibiotic treatment for Tuberculosis induces a profound dysbiosis of the microbiome that persists long after therapy is completed. Scientific Reports. 7: 10767. PMID 28883399 DOI: 10.1038/S41598-017-10346-6  0.301
2017 Lacerda-Queiroz N, Riteau N, Eastman RT, Bock KW, Orandle MS, Moore IN, Sher A, Long CA, Jankovic D, Su XZ. Mechanism of splenic cell death and host mortality in a Plasmodium yoelii malaria model. Scientific Reports. 7: 10438. PMID 28874800 DOI: 10.1038/S41598-017-10776-2  0.457
2017 Schechter ME, Andrade BB, He T, Richter GH, Tosh KW, Policicchio BB, Singh A, Raehtz KD, Sheikh V, Ma D, Brocca-Cofano E, Apetrei C, Tracy R, Ribeiro RM, Sher A, et al. Inflammatory monocytes expressing tissue factor drive SIV and HIV coagulopathy. Science Translational Medicine. 9. PMID 28855397 DOI: 10.1126/Scitranslmed.Aam5441  0.421
2017 Kawabe T, Jankovic D, Kawabe S, Huang Y, Lee PH, Yamane H, Zhu J, Sher A, Germain RN, Paul WE. Memory-phenotype CD4(+) T cells spontaneously generated under steady-state conditions exert innate TH1-like effector function. Science Immunology. 2. PMID 28783663 DOI: 10.1126/Sciimmunol.Aam9304  0.343
2017 Namasivayam S, Maiga M, Yuan W, Thovarai V, Costa DL, Mittereder LR, Wipperman MF, Glickman MS, Dzutsev A, Trinchieri G, Sher A. Longitudinal profiling reveals a persistent intestinal dysbiosis triggered by conventional anti-tuberculosis therapy. Microbiome. 5: 71. PMID 28683818 DOI: 10.1186/S40168-017-0286-2  0.348
2017 Iwata S, Mikami Y, Sun HW, Brooks SR, Jankovic D, Hirahara K, Onodera A, Shih HY, Kawabe T, Jiang K, Nakayama T, Sher A, O'Shea JJ, Davis FP, Kanno Y. The Transcription Factor T-bet Limits Amplification of Type I IFN Transcriptome and Circuitry in T Helper 1 Cells. Immunity. PMID 28623086 DOI: 10.1016/J.Immuni.2017.05.005  0.417
2017 Rockwood N, Costa DL, Amaral EP, Du Bruyn E, Kubler A, Gil-Santana L, Fukutani KF, Scanga CA, Flynn JL, Jackson SH, Wilkinson KA, Bishai WR, Sher A, Wilkinson RJ, Andrade BB. Mycobacterium tuberculosis Induction of Heme Oxygenase-1 Expression Is Dependent on Oxidative Stress and Reflects Treatment Outcomes. Frontiers in Immunology. 8: 542. PMID 28553288 DOI: 10.3389/Fimmu.2017.00542  0.349
2017 Radtke AJ, Anderson CF, Riteau N, Rausch K, Scaria P, Kelnhofer ER, Howard RF, Sher A, Germain RN, Duffy P. Adjuvant and carrier protein-dependent T-cell priming promotes a robust antibody response against the Plasmodium falciparum Pfs25 vaccine candidate. Scientific Reports. 7: 40312. PMID 28091576 DOI: 10.1038/Srep40312  0.331
2017 Sher A, Tosh K, Jankovic D. Innate recognition of Toxoplasma gondii in humans involves a mechanism distinct from that utilized by rodents. Cellular & Molecular Immunology. 14: 36-42. PMID 27157497 DOI: 10.1038/Cmi.2016.12  0.465
2016 Poholek AC, Jankovic D, Villarino AV, Petermann F, Hettinga A, Shouval DS, Snapper SB, Kaech SM, Brooks SR, Vahedi G, Sher A, Kanno Y, O'Shea JJ. IL-10 induces a STAT3-dependent autoregulatory loop in TH2 cells that promotes Blimp-1 restriction of cell expansion via antagonism of STAT5 target genes. Science Immunology. 1. PMID 28713870 DOI: 10.1126/Sciimmunol.Aaf8612  0.408
2016 Kugler DG, Flomerfelt FA, Costa DL, Laky K, Kamenyeva O, Mittelstadt PR, Gress RE, Rosshart SP, Rehermann B, Ashwell JD, Sher A, Jankovic D. Systemic toxoplasma infection triggers a long-term defect in the generation and function of naive T lymphocytes. The Journal of Experimental Medicine. PMID 27849554 DOI: 10.1084/Jem.20151636  0.447
2016 Sher A. A Third signal from Conditioned DCs dictates microbial effector choice Nature Reviews Immunology. 16: 721-721. PMID 27841281 DOI: 10.1038/Nri.2016.126  0.317
2016 Iwamura C, Bouladoux N, Belkaid Y, Sher A, Jankovic D. Sensing of the microbiota by NOD1 in mesenchymal stromal cells regulates murine hematopoiesis. Blood. PMID 27799160 DOI: 10.1182/Blood-2016-06-723742  0.385
2016 Riteau N, Radtke AJ, Shenderov K, Mittereder L, Oland SD, Hieny S, Jankovic D, Sher A. Water-in-Oil-Only Adjuvants Selectively Promote T Follicular Helper Cell Polarization through a Type I IFN and IL-6-Dependent Pathway. Journal of Immunology (Baltimore, Md. : 1950). 197: 3884-3893. PMID 27798160 DOI: 10.4049/Jimmunol.1600883  0.429
2016 Costa DL, Namasivayam S, Amaral EP, Arora K, Chao A, Mittereder LR, Maiga M, Boshoff HI, Barry CE, Goulding CW, Andrade BB, Sher A. Pharmacological Inhibition of Host Heme Oxygenase-1 Suppresses Mycobacterium tuberculosis Infection In Vivo by a Mechanism Dependent on T Lymphocytes. Mbio. 7. PMID 27795400 DOI: 10.1128/Mbio.01675-16  0.432
2016 Arbore G, West EE, Spolski R, Robertson AA, Klos A, Rheinheimer C, Dutow P, Woodruff TM, Yu ZX, O'Neill LA, Coll RC, Sher A, Leonard WJ, Köhl J, Monk P, et al. T helper 1 immunity requires complement-driven NLRP3 inflammasome activity in CD4⁺ T cells. Science (New York, N.Y.). 352: aad1210. PMID 27313051 DOI: 10.1126/Science.Aad1210  0.43
2016 Riteau N, Sher A. Chitosan: An Adjuvant with an Unanticipated STING. Immunity. 44: 522-4. PMID 26982361 DOI: 10.1016/J.Immuni.2016.03.002  0.36
2015 Tosh KW, Mittereder L, Bonne-Annee S, Hieny S, Nutman TB, Singer SM, Sher A, Jankovic D. The IL-12 Response of Primary Human Dendritic Cells and Monocytes to Toxoplasma gondii Is Stimulated by Phagocytosis of Live Parasites Rather Than Host Cell Invasion. Journal of Immunology (Baltimore, Md. : 1950). PMID 26597011 DOI: 10.4049/Jimmunol.1501558  0.483
2015 Andrade BB, Pavan Kumar N, Amaral EP, Riteau N, Mayer-Barber KD, Tosh KW, Maier N, Conceição EL, Kubler A, Sridhar R, Banurekha VV, Jawahar MS, Barbosa T, Manganiello VC, Moss J, ... ... Sher A, et al. Heme Oxygenase-1 Regulation of Matrix Metalloproteinase-1 Expression Underlies Distinct Disease Profiles in Tuberculosis. Journal of Immunology (Baltimore, Md. : 1950). 195: 2763-73. PMID 26268658 DOI: 10.4049/Jimmunol.1500942  0.322
2015 Tassi I, Claudio E, Wang H, Tang W, Ha HL, Saret S, Sher A, Jankovic D, Siebenlist U. Adaptive immune-mediated host resistance to Toxoplasma gondii is governed by the NF-κB regulator Bcl-3 in dendritic cells. European Journal of Immunology. 45: 1972-9. PMID 25884683 DOI: 10.1002/Eji.201445045  0.502
2015 Mayer-Barber KD, Sher A. Cytokine and lipid mediator networks in tuberculosis. Immunological Reviews. 264: 264-75. PMID 25703565 DOI: 10.1111/Imr.12249  0.432
2015 McNab F, Mayer-Barber K, Sher A, Wack A, O'Garra A. Type I interferons in infectious disease. Nature Reviews. Immunology. 15: 87-103. PMID 25614319 DOI: 10.1038/Nri3787  0.474
2015 Sher A, Antonelli L, Feng C, Costa D, Andrade B, O’Garra A, Mayer-Marber K. ID: 15: The probacterial activity of Type I interferons: a target for disease intervention? Cytokine. 76: 59-60. DOI: 10.1016/J.Cyto.2015.08.019  0.403
2014 Cardone M, Dzutsev AK, Li H, Riteau N, Gerosa F, Shenderov K, Winkler-Pickett R, Provezza L, Riboldi E, Leighty RM, Orr SJ, Steinhagen F, Wewers MD, Sher A, Anderson SK, et al. Interleukin-1 and interferon-γ orchestrate β-glucan-activated human dendritic cell programming via IκB-ζ modulation. Plos One. 9: e114516. PMID 25474109 DOI: 10.1371/Journal.Pone.0114516  0.436
2014 Andrade BB, Singh A, Narendran G, Schechter ME, Nayak K, Subramanian S, Anbalagan S, Jensen SM, Porter BO, Antonelli LR, Wilkinson KA, Wilkinson RJ, Meintjes G, van der Plas H, Follmann D, ... ... Sher A, et al. Mycobacterial antigen driven activation of CD14++CD16- monocytes is a predictor of tuberculosis-associated immune reconstitution inflammatory syndrome. Plos Pathogens. 10: e1004433. PMID 25275318 DOI: 10.1371/Journal.Ppat.1004433  0.407
2014 Mayer-Barber KD, Andrade BB, Oland SD, Amaral EP, Barber DL, Gonzales J, Derrick SC, Shi R, Kumar NP, Wei W, Yuan X, Zhang G, Cai Y, Babu S, Catalfamo M, ... ... Sher A, et al. Host-directed therapy of tuberculosis based on interleukin-1 and type I interferon crosstalk. Nature. 511: 99-103. PMID 24990750 DOI: 10.1038/Nature13489  0.489
2014 Escobar TM, Kanellopoulou C, Kugler DG, Kilaru G, Nguyen CK, Nagarajan V, Bhairavabhotla RK, Northrup D, Zahr R, Burr P, Liu X, Zhao K, Sher A, Jankovic D, Zhu J, et al. miR-155 activates cytokine gene expression in Th17 cells by regulating the DNA-binding protein Jarid2 to relieve polycomb-mediated repression. Immunity. 40: 865-79. PMID 24856900 DOI: 10.1016/J.Immuni.2014.03.014  0.345
2014 Gorfu G, Cirelli KM, Melo MB, Mayer-Barber K, Crown D, Koller BH, Masters S, Sher A, Leppla SH, Moayeri M, Saeij JP, Grigg ME. Dual role for inflammasome sensors NLRP1 and NLRP3 in murine resistance to Toxoplasma gondii. Mbio. 5. PMID 24549849 DOI: 10.1128/Mbio.01117-13  0.473
2014 Gazzinelli RT, Mendonça-Neto R, Lilue J, Howard J, Sher A. Innate resistance against Toxoplasma gondii: an evolutionary tale of mice, cats, and men. Cell Host & Microbe. 15: 132-8. PMID 24528860 DOI: 10.1016/J.Chom.2014.01.004  0.426
2014 Shenderov K, Riteau N, Yip R, Mayer-Barber KD, Oland S, Hieny S, Fitzgerald P, Oberst A, Dillon CP, Green DR, Cerundolo V, Sher A. Cutting edge: Endoplasmic reticulum stress licenses macrophages to produce mature IL-1β in response to TLR4 stimulation through a caspase-8- and TRIF-dependent pathway. Journal of Immunology (Baltimore, Md. : 1950). 192: 2029-33. PMID 24489101 DOI: 10.4049/Jimmunol.1302549  0.362
2014 Barber DL, Andrade BB, McBerry C, Sereti I, Sher A. Role of IL-6 in Mycobacterium avium--associated immune reconstitution inflammatory syndrome. Journal of Immunology (Baltimore, Md. : 1950). 192: 676-82. PMID 24337386 DOI: 10.4049/Jimmunol.1301004  0.498
2014 Redford PS, Mayer-Barber KD, McNab FW, Stavropoulos E, Wack A, Sher A, O'Garra A. Influenza A virus impairs control of Mycobacterium tuberculosis coinfection through a type I interferon receptor-dependent pathway. The Journal of Infectious Diseases. 209: 270-4. PMID 23935205 DOI: 10.1093/Infdis/Jit424  0.378
2013 Kugler DG, Mittelstadt PR, Ashwell JD, Sher A, Jankovic D. CD4+ T cells are trigger and target of the glucocorticoid response that prevents lethal immunopathology in toxoplasma infection. The Journal of Experimental Medicine. 210: 1919-27. PMID 23980098 DOI: 10.1084/Jem.20122300  0.522
2013 Narendran G, Andrade BB, Porter BO, Chandrasekhar C, Venkatesan P, Menon PA, Subramanian S, Anbalagan S, Bhavani KP, Sekar S, Padmapriyadarshini C, Kumar S, Ravichandran N, Raja K, Bhanu K, ... ... Sher A, et al. Paradoxical tuberculosis immune reconstitution inflammatory syndrome (TB-IRIS) in HIV patients with culture confirmed pulmonary tuberculosis in India and the potential role of IL-6 in prediction. Plos One. 8: e63541. PMID 23691062 DOI: 10.1371/Journal.Pone.0063541  0.334
2013 Andrade BB, Pavan Kumar N, Mayer-Barber KD, Barber DL, Sridhar R, Rekha VV, Jawahar MS, Nutman TB, Sher A, Babu S. Plasma heme oxygenase-1 levels distinguish latent or successfully treated human tuberculosis from active disease. Plos One. 8: e62618. PMID 23671613 DOI: 10.1371/Journal.Pone.0062618  0.357
2013 Shenderov K, Barber DL, Mayer-Barber KD, Gurcha SS, Jankovic D, Feng CG, Oland S, Hieny S, Caspar P, Yamasaki S, Lin X, Ting JP, Trinchieri G, Besra GS, Cerundolo V, ... Sher A, et al. Cord factor and peptidoglycan recapitulate the Th17-promoting adjuvant activity of mycobacteria through mincle/CARD9 signaling and the inflammasome. Journal of Immunology (Baltimore, Md. : 1950). 190: 5722-30. PMID 23630357 DOI: 10.4049/Jimmunol.1203343  0.462
2013 Mackey-Lawrence NM, Guo X, Sturdevant DE, Virtaneva K, Hernandez MM, Houpt E, Sher A, Porcella SF, Petri WA. Effect of the leptin receptor Q223R polymorphism on the host transcriptome following infection with Entamoeba histolytica. Infection and Immunity. 81: 1460-70. PMID 23429533 DOI: 10.1128/IAI.01383-12  0.401
2013 Koblansky AA, Jankovic D, Oh H, Hieny S, Sungnak W, Mathur R, Hayden MS, Akira S, Sher A, Ghosh S. Recognition of profilin by Toll-like receptor 12 is critical for host resistance to Toxoplasma gondii. Immunity. 38: 119-30. PMID 23246311 DOI: 10.1016/J.Immuni.2012.09.016  0.493
2012 Wasmuth JD, Pszenny V, Haile S, Jansen EM, Gast AT, Sher A, Boyle JP, Boulanger MJ, Parkinson J, Grigg ME. Integrated bioinformatic and targeted deletion analyses of the SRS gene superfamily identify SRS29C as a negative regulator of Toxoplasma virulence. Mbio. 3. PMID 23149485 DOI: 10.1128/Mbio.00321-12  0.303
2012 Rothfuchs AG, Roffê E, Gibson A, Cheever AW, Ezekowitz RA, Takahashi K, Steindel M, Sher A, Báfica A. Mannose-binding lectin regulates host resistance and pathology during experimental infection with Trypanosoma cruzi. Plos One. 7: e47835. PMID 23139754 DOI: 10.1371/Journal.Pone.0047835  0.718
2012 Abdalla H, Srinivasan L, Shah S, Mayer-Barber KD, Sher A, Sutterwala FS, Briken V. Mycobacterium tuberculosis infection of dendritic cells leads to partially caspase-1/11-independent IL-1β and IL-18 secretion but not to pyroptosis. Plos One. 7: e40722. PMID 22911706 DOI: 10.1371/Journal.Pone.0040722  0.451
2012 Pearce EJ, Caspar P, Grzych JM, Lewis FA, Sher A. Pillars article: downregulation of Th1 cytokine production accompanies induction of Th2 responses by a parasitic helminth, Schistosoma mansoni. J. Exp. Med. 1991. 173: 159-166. Journal of Immunology (Baltimore, Md. : 1950). 189: 1104-11. PMID 22815380  0.412
2012 Goldszmid RS, Caspar P, Rivollier A, White S, Dzutsev A, Hieny S, Kelsall B, Trinchieri G, Sher A. NK cell-derived interferon-γ orchestrates cellular dynamics and the differentiation of monocytes into dendritic cells at the site of infection. Immunity. 36: 1047-59. PMID 22749354 DOI: 10.1016/J.Immuni.2012.03.026  0.476
2012 Shi CS, Shenderov K, Huang NN, Kabat J, Abu-Asab M, Fitzgerald KA, Sher A, Kehrl JH. Activation of autophagy by inflammatory signals limits IL-1β production by targeting ubiquitinated inflammasomes for destruction. Nature Immunology. 13: 255-63. PMID 22286270 DOI: 10.1038/Ni.2215  0.364
2012 Barber DL, Andrade BB, Sereti I, Sher A. Immune reconstitution inflammatory syndrome: the trouble with immunity when you had none. Nature Reviews. Microbiology. 10: 150-6. PMID 22230950 DOI: 10.1038/Nrmicro2712  0.459
2012 Mahnke YD, Greenwald JH, DerSimonian R, Roby G, Antonelli LR, Sher A, Roederer M, Sereti I. Selective expansion of polyfunctional pathogen-specific CD4(+) T cells in HIV-1-infected patients with immune reconstitution inflammatory syndrome. Blood. 119: 3105-12. PMID 22219223 DOI: 10.1182/Blood-2011-09-380840  0.426
2011 Mayer-Barber KD, Andrade BB, Barber DL, Hieny S, Feng CG, Caspar P, Oland S, Gordon S, Sher A. Innate and adaptive interferons suppress IL-1α and IL-1β production by distinct pulmonary myeloid subsets during Mycobacterium tuberculosis infection. Immunity. 35: 1023-34. PMID 22195750 DOI: 10.1016/J.Immuni.2011.12.002  0.457
2011 Mashayekhi M, Sandau MM, Dunay IR, Frickel EM, Khan A, Goldszmid RS, Sher A, Ploegh HL, Murphy TL, Sibley LD, Murphy KM. CD8α(+) dendritic cells are the critical source of interleukin-12 that controls acute infection by Toxoplasma gondii tachyzoites. Immunity. 35: 249-59. PMID 21867928 DOI: 10.1016/J.Immuni.2011.08.008  0.499
2011 Novikov A, Cardone M, Thompson R, Shenderov K, Kirschman KD, Mayer-Barber KD, Myers TG, Rabin RL, Trinchieri G, Sher A, Feng CG. Mycobacterium tuberculosis triggers host type I IFN signaling to regulate IL-1β production in human macrophages. Journal of Immunology (Baltimore, Md. : 1950). 187: 2540-7. PMID 21784976 DOI: 10.4049/Jimmunol.1100926  0.482
2011 Egen JG, Rothfuchs AG, Feng CG, Horwitz MA, Sher A, Germain RN. Intravital imaging reveals limited antigen presentation and T cell effector function in mycobacterial granulomas. Immunity. 34: 807-19. PMID 21596592 DOI: 10.1016/J.Immuni.2011.03.022  0.424
2011 Cooper AM, Mayer-Barber KD, Sher A. Role of innate cytokines in mycobacterial infection. Mucosal Immunology. 4: 252-60. PMID 21430655 DOI: 10.1038/Mi.2011.13  0.474
2011 Duggal P, Guo X, Haque R, Peterson KM, Ricklefs S, Mondal D, Alam F, Noor Z, Verkerke HP, Marie C, Leduc CA, Chua SC, Myers MG, Leibel RL, Houpt E, ... ... Sher A, et al. A mutation in the leptin receptor is associated with Entamoeba histolytica infection in children. The Journal of Clinical Investigation. 121: 1191-8. PMID 21393862 DOI: 10.1172/Jci45294  0.351
2011 Barber DL, Mayer-Barber KD, Feng CG, Sharpe AH, Sher A. CD4 T cells promote rather than control tuberculosis in the absence of PD-1-mediated inhibition. Journal of Immunology (Baltimore, Md. : 1950). 186: 1598-607. PMID 21172867 DOI: 10.4049/Jimmunol.1003304  0.367
2011 Hunn JP, Feng CG, Sher A, Howard JC. The immunity-related GTPases in mammals: a fast-evolving cell-autonomous resistance system against intracellular pathogens. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 22: 43-54. PMID 21052678 DOI: 10.1007/S00335-010-9293-3  0.447
2011 Marakalala MJ, Guler R, Matika L, Murray G, Jacobs M, Brombacher F, Rothfuchs AG, Sher A, Brown GD. The Syk/CARD9-coupled receptor Dectin-1 is not required for host resistance to Mycobacterium tuberculosis in mice. Microbes and Infection / Institut Pasteur. 13: 198-201. PMID 21034845 DOI: 10.1016/J.Micinf.2010.10.013  0.448
2011 Sher A, Mayer-Barber K, Novikov A, Andrade B, Barber D, Shenderov K, Feng C. CS17-1. Cytokine pathways regulating the innate immune response to mycobacteria Cytokine. 56: 107. DOI: 10.1016/J.Cyto.2011.07.415  0.375
2010 Feng CG, Sher A. Parasites paralyze cellular host defense system to promote virulence. Cell Host & Microbe. 8: 463-4. PMID 21147459 DOI: 10.1016/J.Chom.2010.11.012  0.39
2010 Walseng E, Furuta K, Goldszmid RS, Weih KA, Sher A, Roche PA. Dendritic cell activation prevents MHC class II ubiquitination and promotes MHC class II survival regardless of the activation stimulus. The Journal of Biological Chemistry. 285: 41749-54. PMID 21047782 DOI: 10.1074/Jbc.M110.157586  0.328
2010 Coffman RL, Sher A, Seder RA. Vaccine adjuvants: putting innate immunity to work. Immunity. 33: 492-503. PMID 21029960 DOI: 10.1016/J.Immuni.2010.10.002  0.36
2010 Antonelli LR, Mahnke Y, Hodge JN, Porter BO, Barber DL, DerSimonian R, Greenwald JH, Roby G, Mican J, Sher A, Roederer M, Sereti I. Elevated frequencies of highly activated CD4+ T cells in HIV+ patients developing immune reconstitution inflammatory syndrome. Blood. 116: 3818-27. PMID 20660788 DOI: 10.1182/Blood-2010-05-285080  0.383
2010 Barber DL, Mayer-Barber KD, Antonelli LR, Wilson MS, White S, Caspar P, Hieny S, Sereti I, Sher A. Th1-driven immune reconstitution disease in Mycobacterium avium-infected mice. Blood. 116: 3485-93. PMID 20656932 DOI: 10.1182/Blood-2010-05-286336  0.469
2010 Antonelli LR, Gigliotti Rothfuchs A, Gonçalves R, Roffê E, Cheever AW, Bafica A, Salazar AM, Feng CG, Sher A. Intranasal Poly-IC treatment exacerbates tuberculosis in mice through the pulmonary recruitment of a pathogen-permissive monocyte/macrophage population. The Journal of Clinical Investigation. 120: 1674-82. PMID 20389020 DOI: 10.1172/Jci40817  0.724
2010 Wilson MS, Feng CG, Barber DL, Yarovinsky F, Cheever AW, Sher A, Grigg M, Collins M, Fouser L, Wynn TA. Redundant and pathogenic roles for IL-22 in mycobacterial, protozoan, and helminth infections. Journal of Immunology (Baltimore, Md. : 1950). 184: 4378-90. PMID 20220096 DOI: 10.4049/Jimmunol.0903416  0.418
2010 Min-Oo G, Ayi K, Bongfen SE, Tam M, Radovanovic I, Gauthier S, Santiago H, Rothfuchs AG, Roffê E, Sher A, Mullick A, Fortin A, Stevenson MM, Kain KC, Gros P. Cysteamine, the natural metabolite of pantetheinase, shows specific activity against Plasmodium. Experimental Parasitology. 125: 315-24. PMID 20219464 DOI: 10.1016/J.Exppara.2010.02.009  0.429
2010 Jankovic D, Kugler DG, Sher A. IL-10 production by CD4+ effector T cells: a mechanism for self-regulation. Mucosal Immunology. 3: 239-46. PMID 20200511 DOI: 10.1038/Mi.2010.8  0.485
2010 Mayer-Barber KD, Barber DL, Shenderov K, White SD, Wilson MS, Cheever A, Kugler D, Hieny S, Caspar P, Núñez G, Schlueter D, Flavell RA, Sutterwala FS, Sher A. Caspase-1 independent IL-1beta production is critical for host resistance to mycobacterium tuberculosis and does not require TLR signaling in vivo. Journal of Immunology (Baltimore, Md. : 1950). 184: 3326-30. PMID 20200276 DOI: 10.4049/Jimmunol.0904189  0.446
2010 Goldszmid RS, Sher A. Processing and presentation of antigens derived from intracellular protozoan parasites. Current Opinion in Immunology. 22: 118-23. PMID 20153156 DOI: 10.1016/J.Coi.2010.01.017  0.423
2010 Gros GL, Harvie M, Camberis M, Tang S, Brinkmann V, Wong S, Neill DR, Bellosi A, Bucks C, Kane CM, Fallon PG, McKenzie ANJ, Obata K, Yoshikawa S, Ishiwata K, ... ... Sher A, et al. Immunity to helminth infection (WS-091) Chairpersons: Tomohiro Yoshimoto, Graham LeGros International Immunology. 22. DOI: 10.1093/Intimm/Dxq345  0.418
2010 Gros GL, Harvie M, Camberis M, Tang S, Brinkmann V, Wong S, Neill DR, Bellosi A, Bucks C, Kane CM, Fallon PG, McKenzie ANJ, Obata K, Yoshikawa S, Ishiwata K, ... ... Sher A, et al. Immunity to helminth infection (PP-091) Chairperson: Tomohiro Yoshimoto International Immunology. 22. DOI: 10.1093/Intimm/Dxq344  0.417
2010 Hill AVS, Kaye P, Sher A, Jankovic D, Ghosh S, Koblansky A, Trinchieri G, Goldszmid R, Nakanishi K, Wynn T, Yazdanbakhsh M. Infection 3 Protozoal and helminth infection (SY1-5) Chairpersons: Kenji Nakanishi, Maria Yazdanbakhsh International Immunology. 22. DOI: 10.1093/Intimm/Dxq282  0.346
2009 Sassi A, Brichacek B, Hieny S, Yarovinsky F, Golding H, Grivel JC, Sher A, Margolis L. Toxoplasma gondii inhibits R5 HIV-1 replication in human lymphoid tissues ex vivo. Microbes and Infection / Institut Pasteur. 11: 1106-13. PMID 19671446 DOI: 10.1016/J.Micinf.2009.08.004  0.327
2009 Steinfelder S, Andersen JF, Cannons JL, Feng CG, Joshi M, Dwyer D, Caspar P, Schwartzberg PL, Sher A, Jankovic D. The major component in schistosome eggs responsible for conditioning dendritic cells for Th2 polarization is a T2 ribonuclease (omega-1). The Journal of Experimental Medicine. 206: 1681-90. PMID 19635859 DOI: 10.1084/Jem.20082462  0.403
2009 la Sala A, He J, Laricchia-Robbio L, Gorini S, Iwasaki A, Braun M, Yap GS, Sher A, Ozato K, Kelsall B. Cholera toxin inhibits IL-12 production and CD8alpha+ dendritic cell differentiation by cAMP-mediated inhibition of IRF8 function. The Journal of Experimental Medicine. 206: 1227-35. PMID 19487420 DOI: 10.1084/Jem.20080912  0.41
2009 Rothfuchs AG, Egen JG, Feng CG, Antonelli LR, Bafica A, Winter N, Locksley RM, Sher A. In situ IL-12/23p40 production during mycobacterial infection is sustained by CD11bhigh dendritic cells localized in tissue sites distinct from those harboring bacilli. Journal of Immunology (Baltimore, Md. : 1950). 182: 6915-25. PMID 19454688 DOI: 10.4049/Jimmunol.0900074  0.71
2009 Henry SC, Daniell XG, Burroughs AR, Indaram M, Howell DN, Coers J, Starnbach MN, Hunn JP, Howard JC, Feng CG, Sher A, Taylor GA. Balance of Irgm protein activities determines IFN-gamma-induced host defense. Journal of Leukocyte Biology. 85: 877-85. PMID 19176402 DOI: 10.1189/Jlb.1008599  0.42
2009 Goldszmid RS, Coppens I, Lev A, Caspar P, Mellman I, Sher A. Host ER-parasitophorous vacuole interaction provides a route of entry for antigen cross-presentation in Toxoplasma gondii-infected dendritic cells. The Journal of Experimental Medicine. 206: 399-410. PMID 19153244 DOI: 10.1084/Jem.20082108  0.426
2009 Feng CG, Zheng L, Lenardo MJ, Sher A. Interferon-inducible immunity-related GTPase Irgm1 regulates IFN gamma-dependent host defense, lymphocyte survival and autophagy. Autophagy. 5: 232-4. PMID 19066452 DOI: 10.4161/Auto.5.2.7445  0.481
2009 La Sala A, He J, Laricchia-Robbio L, Gorini S, Iwasaki A, Braun M, Yap GS, Sher A, Ozato K, Kelsall B. Cholera toxin inhibits IL-12 production and CD8α+ dendritic cell differentiation by cAMP-mediated inhibition of IRF8 function (Journal of Experimental Medicine (2009) 206, 6, (1227-1235)) Journal of Experimental Medicine. 206: 1635. DOI: 10.1084/Jem.2008091262209C  0.357
2008 Yarovinsky F, Hieny S, Sher A. Recognition of Toxoplasma gondii by TLR11 Prevents Parasite-Induced Immunopathology Journal of Immunology. 181: 8478-8484. PMID 19050265 DOI: 10.4049/Jimmunol.181.12.8478  0.456
2008 Watford WT, Hissong BD, Durant LR, Yamane H, Muul LM, Kanno Y, Tato CM, Ramos HL, Berger AE, Mielke L, Pesu M, Solomon B, Frucht DM, Paul WE, Sher A, et al. Tpl2 kinase regulates T cell interferon-gamma production and host resistance to Toxoplasma gondii. The Journal of Experimental Medicine. 205: 2803-12. PMID 19001140 DOI: 10.1084/Jem.20081461  0.461
2008 Sahu N, Venegas AM, Jankovic D, Mitzner W, Gomez-Rodriguez J, Cannons JL, Sommers C, Love P, Sher A, Schwartzberg PL, August A. Selective expression rather than specific function of Txk and Itk regulate Th1 and Th2 responses. Journal of Immunology (Baltimore, Md. : 1950). 181: 6125-31. PMID 18941202 DOI: 10.4049/Jimmunol.181.9.6125  0.397
2008 Feng CG, Zheng L, Jankovic D, Báfica A, Cannons JL, Watford WT, Chaussabel D, Hieny S, Caspar P, Schwartzberg PL, Lenardo MJ, Sher A. The immunity-related GTPase Irgm1 promotes the expansion of activated CD4+ T cell populations by preventing interferon-gamma-induced cell death. Nature Immunology. 9: 1279-87. PMID 18806793 DOI: 10.1038/Ni.1653  0.731
2008 West NP, Wozniak TM, Valenzuela J, Feng CG, Sher A, Ribeiro JMC, Britton WJ. Immunological diversity within a family of cutinase-like proteins of Mycobacterium tuberculosis. Vaccine. 26: 3853-3859. PMID 18565629 DOI: 10.1016/J.Vaccine.2008.05.007  0.404
2008 Sampaio EP, Elloumi HZ, Zelazny A, Ding L, Paulson ML, Sher A, Bafica AL, Shea YR, Holland SM. Mycobacterium abscessus and M. avium trigger Toll-like receptor 2 and distinct cytokine response in human cells. American Journal of Respiratory Cell and Molecular Biology. 39: 431-9. PMID 18441280 DOI: 10.1165/Rcmb.2007-0413Oc  0.696
2008 Feng CG, Weksberg DC, Taylor GA, Sher A, Goodell MA. The p47 GTPase Lrg-47 (Irgm1) links host defense and hematopoietic stem cell proliferation. Cell Stem Cell. 2: 83-9. PMID 18371424 DOI: 10.1016/J.Stem.2007.10.007  0.378
2008 Plattner F, Yarovinsky F, Romero S, Didry D, Carlier MF, Sher A, Soldati-Favre D. Toxoplasma profilin is essential for host cell invasion and TLR11-dependent induction of an interleukin-12 response. Cell Host & Microbe. 3: 77-87. PMID 18312842 DOI: 10.1016/J.Chom.2008.01.001  0.453
2008 Egen JG, Rothfuchs AG, Feng CG, Winter N, Sher A, Germain RN. Macrophage and T cell dynamics during the development and disintegration of mycobacterial granulomas. Immunity. 28: 271-84. PMID 18261937 DOI: 10.1016/J.Immuni.2007.12.010  0.4
2008 Alter-Koltunoff M, Goren S, Nousbeck J, Feng CG, Sher A, Ozato K, Azriel A, Levi BZ. Innate immunity to intraphagosomal pathogens is mediated by interferon regulatory factor 8 (IRF-8) that stimulates the expression of macrophage-specific Nramp1 through antagonizing repression by c-Myc. The Journal of Biological Chemistry. 283: 2724-33. PMID 18045875 DOI: 10.1074/Jbc.M707704200  0.422
2007 Taylor GA, Feng CG, Sher A. Control of IFN-gamma-mediated host resistance to intracellular pathogens by immunity-related GTPases (p47 GTPases). Microbes and Infection / Institut Pasteur. 9: 1644-51. PMID 18023232 DOI: 10.1016/J.Micinf.2007.09.004  0.431
2007 Goldszmid RS, Bafica A, Jankovic D, Feng CG, Caspar P, Winkler-Pickett R, Trinchieri G, Sher A. TAP-1 indirectly regulates CD4+ T cell priming in Toxoplasma gondii infection by controlling NK cell IFN-gamma production. The Journal of Experimental Medicine. 204: 2591-602. PMID 17923502 DOI: 10.1084/Jem.20070634  0.719
2007 Bafica A, Feng CG, Santiago HC, Aliberti J, Cheever A, Thomas KE, Taylor GA, Vogel SN, Sher A. The IFN-inducible GTPase LRG47 (Irgm1) negatively regulates TLR4-triggered proinflammatory cytokine production and prevents endotoxemia. Journal of Immunology (Baltimore, Md. : 1950). 179: 5514-22. PMID 17911638 DOI: 10.4049/Jimmunol.179.8.5514  0.696
2007 Rothfuchs AG, Bafica A, Feng CG, Egen JG, Williams DL, Brown GD, Sher A. Dectin-1 interaction with Mycobacterium tuberculosis leads to enhanced IL-12p40 production by splenic dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 179: 3463-71. PMID 17785780 DOI: 10.4049/Jimmunol.179.6.3463  0.715
2007 Amsen D, Antov A, Jankovic D, Sher A, Radtke F, Souabni A, Busslinger M, McCright B, Gridley T, Flavell RA. Direct regulation of Gata3 expression determines the T helper differentiation potential of Notch. Immunity. 27: 89-99. PMID 17658279 DOI: 10.1016/J.Immuni.2007.05.021  0.387
2007 Trinchieri G, Sher A. Cooperation of Toll-like receptor signals in innate immune defence Nature Reviews Immunology. 7: 179-190. PMID 17318230 DOI: 10.1038/Nri2038  0.38
2007 Jankovic D, Kullberg MC, Feng CG, Goldszmid RS, Collazo CM, Wilson M, Wynn TA, Kamanaka M, Flavell RA, Sher A. Conventional T-bet(+)Foxp3(-) Th1 cells are the major source of host-protective regulatory IL-10 during intracellular protozoan infection. The Journal of Experimental Medicine. 204: 273-83. PMID 17283209 DOI: 10.1084/Jem.20062175  0.475
2007 Scanga CA, Bafica A, Sher A. Viral gene expression in HIV transgenic mice is activated by Mycobacterium tuberculosis and suppressed after antimycobacterial chemotherapy. The Journal of Infectious Diseases. 195: 246-54. PMID 17191170 DOI: 10.1086/510244  0.682
2007 Weksberg DC, Feng CG, Sher A, Goodell MA. The P47 GTPase Lrg-47 Links Host Defense and HSC Proliferation. Blood. 110: 640-640. DOI: 10.1182/Blood.V110.11.640.640  0.434
2006 Feng CG, Kaviratne M, Rothfuchs AG, Cheever A, Hieny S, Young HA, Wynn TA, Sher A. NK cell-derived IFN-gamma differentially regulates innate resistance and neutrophil response in T cell-deficient hosts infected with Mycobacterium tuberculosis. Journal of Immunology (Baltimore, Md. : 1950). 177: 7086-93. PMID 17082625 DOI: 10.4049/Jimmunol.177.10.7086  0.533
2006 Kullberg MC, Jankovic D, Feng CG, Hue S, Gorelick PL, McKenzie BS, Cua DJ, Powrie F, Cheever AW, Maloy KJ, Sher A. IL-23 plays a key role in Helicobacter hepaticus-induced T cell-dependent colitis Journal of Experimental Medicine. 203: 2485-2494. PMID 17030948 DOI: 10.1084/Jem.20061082  0.417
2006 Yarovinsky F, Kanzler H, Hieny S, Coffman RL, Sher A. Toll-like receptor recognition regulates immunodominance in an antimicrobial CD4+ T cell response. Immunity. 25: 655-64. PMID 17000122 DOI: 10.1016/J.Immuni.2006.07.015  0.418
2006 Bertholet S, Goldszmid R, Morrot A, Debrabant A, Afrin F, Collazo-Custodio C, Houde M, Desjardins M, Sher A, Sacks D. Leishmania antigens are presented to CD8+ T cells by a transporter associated with antigen processing-independent pathway in vitro and in vivo Journal of Immunology. 177: 3525-3533. PMID 16951311 DOI: 10.4049/Jimmunol.177.6.3525  0.384
2006 Bafica A, Santiago HC, Goldszmid R, Ropert C, Gazzinelli RT, Sher A. Cutting edge: TLR9 and TLR2 signaling together account for MyD88-dependent control of parasitemia in Trypanosoma cruzi infection. Journal of Immunology (Baltimore, Md. : 1950). 177: 3515-9. PMID 16951309 DOI: 10.4049/Jimmunol.177.6.3515  0.737
2006 Cannons JL, Yu LJ, Jankovic D, Crotty S, Horai R, Kirby M, Anderson S, Cheever AW, Sher A, Schwartzberg PL. SAP regulates T cell-mediated help for humoral immunity by a mechanism distinct from cytokine regulation. The Journal of Experimental Medicine. 203: 1551-65. PMID 16754717 DOI: 10.1084/Jem.20052097  0.458
2006 Dear JW, Yasuda H, Hu X, Hieny S, Yuen PS, Hewitt SM, Sher A, Star RA. Sepsis-induced organ failure is mediated by different pathways in the kidney and liver: acute renal failure is dependent on MyD88 but not renal cell apoptosis. Kidney International. 69: 832-836. PMID 16518342 DOI: 10.1038/Sj.Ki.5000165  0.336
2006 Collazo CM, Sher A, Meierovics AI, Elkins KL. Myeloid differentiation factor-88 (MyD88) is essential for control of primary in vivo Francisella tularensis LVS infection, but not for control of intra-macrophage bacterial replication. Microbes and Infection / Institut Pasteur. 8: 779-90. PMID 16513388 DOI: 10.1016/J.Micinf.2005.09.014  0.461
2006 Yap GS, Shaw MH, Ling Y, Sher A. Genetic analysis of host resistance to intracellular pathogens: lessons from studies of Toxoplasma gondii infection. Microbes and Infection / Institut Pasteur. 8: 1174-8. PMID 16513380 DOI: 10.1016/J.Micinf.2005.10.031  0.425
2006 Yarovinsky F, Sher A. Toll-like receptor recognition of Toxoplasma gondii International Journal For Parasitology. 36: 255-259. PMID 16476433 DOI: 10.1016/J.Ijpara.2005.12.003  0.432
2006 Jankovic D, Steinfelder S, Kullberg MC, Sher A. Mechanisms underlying helminth-induced Th2 polarization : Default, negative or positive pathways? Chemical Immunology and Allergy. 90: 65-81. PMID 16210903 DOI: 10.1159/000088881  0.377
2005 Bafica A, Scanga CA, Feng CG, Leifer C, Cheever A, Sher A. TLR9 regulates Th1 responses and cooperates with TLR2 in mediating optimal resistance to Mycobacterium tuberculosis. The Journal of Experimental Medicine. 202: 1715-24. PMID 16365150 DOI: 10.1084/Jem.20051782  0.73
2005 Santiago HC, Feng CG, Bafica A, Roffe E, Arantes RM, Cheever A, Taylor G, Vieira LQ, Vierira LQ, Aliberti J, Gazzinelli RT, Sher A. Mice deficient in LRG-47 display enhanced susceptibility to Trypanosoma cruzi infection associated with defective hemopoiesis and intracellular control of parasite growth. Journal of Immunology (Baltimore, Md. : 1950). 175: 8165-72. PMID 16339555 DOI: 10.4049/Jimmunol.175.12.8165  0.732
2005 Kullberg MC, Hay V, Cheever AW, Mamura M, Sher A, Letterio JJ, Shevach EM, Piccirillo CA. TGF-beta1 production by CD4+ CD25+ regulatory T cells is not essential for suppression of intestinal inflammation. European Journal of Immunology. 35: 2886-95. PMID 16180248 DOI: 10.1002/Eji.200526106  0.323
2005 Bafica A, Scanga CA, Serhan C, Machado F, White S, Sher A, Aliberti J. Host control of Mycobacterium tuberculosis is regulated by 5-lipoxygenase-dependent lipoxin production. The Journal of Clinical Investigation. 115: 1601-6. PMID 15931391 DOI: 10.1172/Jci23949  0.736
2005 Butcher BA, Greene RI, Henry SC, Annecharico KL, Weinberg JB, Denkers EY, Sher A, Taylor GA. p47 GTPases regulate Toxoplasma gondii survival in activated macrophages. Infection and Immunity. 73: 3278-86. PMID 15908352 DOI: 10.1128/Iai.73.6.3278-3286.2005  0.452
2005 Yarovinsky F, Zhang D, Andersen JF, Bannenberg GL, Serhan CN, Hayden MS, Hieny S, Sutterwala FS, Flavell RA, Ghosh S, Sher A. TLR11 activation of dendritic cells by a protozoan profilin-like protein. Science (New York, N.Y.). 308: 1626-9. PMID 15860593 DOI: 10.1126/Science.1109893  0.476
2005 Sher A, Kullberg M. Effector and regulatory CD4+ T cell function in a murine model of helicobacter hepaticus-induced colitis Journal of Pediatric Gastroenterology and Nutrition. 40. PMID 15805844 DOI: 10.1097/00005176-200504001-00021  0.336
2005 Feng CG, Jankovic D, Kullberg M, Cheever A, Scanga CA, Hieny S, Caspar P, Yap GS, Sher A. Maintenance of pulmonary Th1 effector function in chronic tuberculosis requires persistent IL-12 production. Journal of Immunology (Baltimore, Md. : 1950). 174: 4185-92. PMID 15778379 DOI: 10.4049/Jimmunol.174.7.4185  0.508
2005 Arita M, Bianchini F, Aliberti J, Sher A, Chiang N, Hong S, Yang R, Petasis NA, Serhan CN. Stereochemical assignment, antiinflammatory properties, and receptor for the omega-3 lipid mediator resolvin E1. The Journal of Experimental Medicine. 201: 713-22. PMID 15753205 DOI: 10.1084/Jem.20042031  0.333
2005 Weksberg D, Feng CG, Sher A, Goodell MA. The Interferon-Inducible GTPase LRG-47 Regulates Hematopoietic Stem Cell Proliferation and Is Required for Maintenance of Normal Hematopoiesis during Microbial Infection. Blood. 106: 2266-2266. DOI: 10.1182/Blood.V106.11.2266.2266  0.375
2004 Yarovinsky F, Andersen JF, King LR, Caspar P, Aliberti J, Golding H, Sher A. Structural Determinants of the Anti-HIV Activity of a CCR5 Antagonist Derived from Toxoplasma gondii Journal of Biological Chemistry. 279: 53635-53642. PMID 15469936 DOI: 10.1074/Jbc.M410550200  0.326
2004 Aliberti J, Jankovic D, Sher A. Turning it on and off: regulation of dendritic cell function in Toxoplasma gondii infection. Immunological Reviews. 201: 26-34. PMID 15361230 DOI: 10.1111/J.0105-2896.2004.00179.X  0.486
2004 Jankovic D, Kullberg MC, Caspar P, Sher A. Parasite-Induced Th2 Polarization Is Associated with Down-Regulated Dendritic Cell Responsiveness to Th1 Stimuli and a Transient Delay in T Lymphocyte Cycling Journal of Immunology. 173: 2419-2427. PMID 15294955 DOI: 10.4049/Jimmunol.173.4.2419  0.423
2004 Báfica A, Scanga CA, Schito M, Chaussabel D, Sher A. Influence of coinfecting pathogens on HIV expression: evidence for a role of Toll-like receptors. Journal of Immunology (Baltimore, Md. : 1950). 172: 7229-34. PMID 15187096 DOI: 10.4049/Jimmunol.172.12.7229  0.66
2004 Del Rio L, Butcher BA, Bennouna S, Hieny S, Sher A, Denkers EY. Toxoplasma gondii triggers myeloid differentiation factor 88-dependent IL-12 and chemokine ligand 2 (monocyte chemoattractant protein 1) responses using distinct parasite molecules and host receptors. Journal of Immunology (Baltimore, Md. : 1950). 172: 6954-60. PMID 15153515 DOI: 10.4049/Jimmunol.172.11.6954  0.44
2004 Taylor GA, Feng CG, Sher A. P47 Gtpases: Regulators Of Immunity To Intracellular Pathogens Nature Reviews Immunology. 4: 100-109. PMID 15040583 DOI: 10.1038/Nri1270  0.471
2004 Scanga CA, Bafica A, Feng CG, Cheever AW, Hieny S, Sher A. MyD88-deficient mice display a profound loss in resistance to Mycobacterium tuberculosis associated with partially impaired Th1 cytokine and nitric oxide synthase 2 expression. Infection and Immunity. 72: 2400-4. PMID 15039368 DOI: 10.1128/Iai.72.4.2400-2404.2004  0.704
2004 Bannenberg GL, Aliberti J, Hong S, Sher A, Serhan C. Exogenous pathogen and plant 15-lipoxygenase initiate endogenous lipoxin A4 biosynthesis. The Journal of Experimental Medicine. 199: 515-23. PMID 14970178 DOI: 10.1084/Jem.20031325  0.453
2004 Feng CG, Collazo-Custodio CM, Eckhaus M, Hieny S, Belkaid Y, Elkins K, Jankovic D, Taylor GA, Sher A. Mice deficient in LRG-47 display increased susceptibility to mycobacterial infection associated with the induction of lymphopenia. Journal of Immunology (Baltimore, Md. : 1950). 172: 1163-8. PMID 14707092 DOI: 10.4049/Jimmunol.172.2.1163  0.512
2004 Báfica A, Scanga CA, Equils O, Sher A. The induction of Toll-like receptor tolerance enhances rather than suppresses HIV-1 gene expression in transgenic mice. Journal of Leukocyte Biology. 75: 460-6. PMID 14657211 DOI: 10.1189/Jlb.0803388  0.7
2004 Sher A, Collazzo C, Scanga C, Jankovic D, Yap G, Aliberti J. Induction and regulation of IL-12-dependent host resistance to Toxoplasma gondii. Immunologic Research. 27: 521-8. PMID 12857995 DOI: 10.1385/Ir:27:2-3:521  0.456
2003 Kullberg MC, Andersen JF, Gorelick PL, Caspar P, Suerbaum S, Fox JG, Cheever AW, Jankovic D, Sher A. Induction of colitis by a CD4+ T cell clone specific for a bacterial epitope. Proceedings of the National Academy of Sciences of the United States of America. 100: 15830-5. PMID 14673119 DOI: 10.1073/Pnas.2534546100  0.465
2003 Feng CG, Scanga CA, Collazo-Custodio CM, Cheever AW, Hieny S, Caspar P, Sher A. Mice lacking myeloid differentiation factor 88 display profound defects in host resistance and immune responses to Mycobacterium avium infection not exhibited by Toll-like receptor 2 (TLR2)- and TLR4-deficient animals. Journal of Immunology (Baltimore, Md. : 1950). 171: 4758-64. PMID 14568952 DOI: 10.4049/Jimmunol.171.9.4758  0.503
2003 Sher A, Pearce E, Kaye P. Shaping the immune response to parasites: role of dendritic cells. Current Opinion in Immunology. 15: 421-9. PMID 12900274 DOI: 10.1016/S0952-7915(03)00072-4  0.431
2003 Huang LY, Aliberti J, Leifer CA, Segal DM, Sher A, Golenbock DT, Golding B. Heat-killed Brucella abortus induces TNF and IL-12p40 by distinct MyD88-dependent pathways: TNF, unlike IL-12p40 secretion, is Toll-like receptor 2 dependent. Journal of Immunology (Baltimore, Md. : 1950). 171: 1441-6. PMID 12874236 DOI: 10.4049/Jimmunol.171.3.1441  0.459
2003 Báfica A, Scanga CA, Schito ML, Hieny S, Sher A. Cutting edge: in vivo induction of integrated HIV-1 expression by mycobacteria is critically dependent on Toll-like receptor 2. Journal of Immunology (Baltimore, Md. : 1950). 171: 1123-7. PMID 12874196 DOI: 10.4049/Jimmunol.171.3.1123  0.69
2003 Golding H, Aliberti J, King LR, Manischewitz J, Andersen J, Valenzuela J, Landau NR, Sher A. Inhibition of HIV-1 infection by a CCR5-binding cyclophilin from Toxoplasma gondii. Blood. 102: 3280-6. PMID 12855560 DOI: 10.1182/Blood-2003-04-1096  0.349
2003 Edwards AD, Chaussabel D, Tomlinson S, Schulz O, Sher A, Sousa CRe. Relationships Among Murine CD11chigh Dendritic Cell Subsets as Revealed by Baseline Gene Expression Patterns Journal of Immunology. 171: 47-60. PMID 12816982 DOI: 10.4049/Jimmunol.171.1.47  0.322
2003 Iqbal J, Hira PR, Al-Ali F, Khalid N, Sher A. Modified Giemsa staining for rapid diagnosis of malaria infection. Medical Principles and Practice : International Journal of the Kuwait University, Health Science Centre. 12: 156-9. PMID 12766332 DOI: 10.1159/000070751  0.313
2003 Aliberti J, Viola JP, Vieira-de-Abreu A, Bozza PT, Sher A, Scharfstein J. Cutting edge: bradykinin induces IL-12 production by dendritic cells: a danger signal that drives Th1 polarization. Journal of Immunology (Baltimore, Md. : 1950). 170: 5349-53. PMID 12759407 DOI: 10.4049/Jimmunol.170.11.5349  0.453
2003 Equils O, Schito ML, Karahashi H, Madak Z, Yarali A, Michelsen KS, Sher A, Arditi M. Toll-like receptor 2 (TLR2) and TLR9 signaling results in HIV-long terminal repeat trans-activation and HIV replication in HIV-1 transgenic mouse spleen cells: implications of simultaneous activation of TLRs on HIV replication. Journal of Immunology (Baltimore, Md. : 1950). 170: 5159-64. PMID 12734363 DOI: 10.4049/Jimmunol.170.10.5159  0.345
2003 Aliberti J, Valenzuela JG, Carruthers VB, Hieny S, Andersen J, Charest H, Reis e Sousa C, Fairlamb A, Ribeiro JM, Sher A. Molecular mimicry of a CCR5 binding-domain in the microbial activation of dendritic cells. Nature Immunology. 4: 485-90. PMID 12665855 DOI: 10.1038/Ni915  0.444
2003 Chaussabel D, Semnani RT, McDowell MA, Sacks D, Sher A, Nutman TB. Unique gene expression profiles of human macrophages and dendritic cells to phylogenetically distinct parasites. Blood. 102: 672-81. PMID 12663451 DOI: 10.1182/Blood-2002-10-3232  0.377
2003 Schito ML, Goel A, Song Y, Inman JK, Fattah RJ, Rice WG, Turpin JA, Sher A, Appella E. In vivo antiviral activity of novel human immunodeficiency virus type 1 nucleocapsid p7 zinc finger inhibitors in a transgenic murine model. Aids Research and Human Retroviruses. 19: 91-101. PMID 12639244 DOI: 10.1089/088922203762688595  0.341
2003 Aliberti J, Serhan C, Sher A. Parasite-induced lipoxin A4 is an endogenous regulator of IL-12 production and immunopathology in Toxoplasma gondii infection. The Journal of Experimental Medicine. 196: 1253-62. PMID 12417634 DOI: 10.1084/Jem.20021183  0.495
2003 Aliberti J, Schulz O, Pennington DJ, Tsujimura H, Sousa CRe, Ozato K, Sher A. Essential role for ICSBP in the in vivo development of murine CD8α+ dendritic cells Blood. 101: 305-310. PMID 12393690 DOI: 10.1182/Blood-2002-04-1088  0.375
2003 Tsujimura H, Tamura T, Gongora C, Aliberti J, Sousa CRe, Sher A, Ozato K. ICSBP/IRF-8 retrovirus transduction rescues dendritic cell development in vitro. Blood. 101: 961-969. PMID 12393459 DOI: 10.1182/Blood-2002-05-1327  0.392
2002 Ozaki K, Spolski R, Feng CG, Qi CF, Cheng J, Sher A, Morse HC, Liu C, Schwartzberg PL, Leonard WJ. A critical role for IL-21 in regulating immunoglobulin production. Science (New York, N.Y.). 298: 1630-4. PMID 12446913 DOI: 10.1126/Science.1077002  0.398
2002 Lqbal J, Sher A, Hira PR, Al-Aniezi A. Drug-resistant Plasmodium falciparum infection in immigrants and non-immune travellers. Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases. 8: 734-8. PMID 12445011 DOI: 10.1046/J.1469-0691.2002.00451.X  0.352
2002 Collazo CM, Yap GS, Hieny S, Caspar P, Feng CG, Taylor GA, Sher A. The function of gamma interferon-inducible GTP-binding protein IGTP in host resistance to Toxoplasma gondii is Stat1 dependent and requires expression in both hematopoietic and nonhematopoietic cellular compartments. Infection and Immunity. 70: 6933-9. PMID 12438372 DOI: 10.1128/Iai.70.12.6933-6939.2002  0.495
2002 Feng CG, Kullberg MC, Jankovic D, Cheever AW, Caspar P, Coffman RL, Sher A. Transgenic mice expressing human interleukin-10 in the antigen-presenting cell compartment show increased susceptibility to infection with Mycobacterium avium associated with decreased macrophage effector function and apoptosis. Infection and Immunity. 70: 6672-9. PMID 12438341 DOI: 10.1128/Iai.70.12.6672-6679.2002  0.543
2002 Sacks D, Sher A. Evasion of innate immunity by parasitic protozoa Nature Immunology. 3: 1041-1047. PMID 12407413 DOI: 10.1038/Ni1102-1041  0.424
2002 Yap GS, Sher A. The use of germ line-mutated mice in understanding host-pathogen interactions. Cellular Microbiology. 4: 627-34. PMID 12366400 DOI: 10.1046/J.1462-5822.2002.00224.X  0.371
2002 Edwards AD, Manickasingham SP, Spörri R, Diebold SS, Schulz O, Sher A, Kaisho T, Akira S, Sousa CRe. Microbial Recognition Via Toll-Like Receptor-Dependent and -Independent Pathways Determines the Cytokine Response of Murine Dendritic Cell Subsets to CD40 Triggering Journal of Immunology. 169: 3652-3660. PMID 12244157 DOI: 10.4049/Jimmunol.169.7.3652  0.455
2002 Kullberg MC, Jankovic D, Gorelick PL, Caspar P, Letterio JJ, Cheever AW, Sher A. Bacteria-triggered CD4(+) T regulatory cells suppress Helicobacter hepaticus-induced colitis. The Journal of Experimental Medicine. 196: 505-15. PMID 12186842 DOI: 10.1084/Jem.20020556  0.45
2002 Aliberti J, Sher A. Role of G-protein-coupled signaling in the induction and regulation of dendritic cell function by Toxoplasma gondii Microbes and Infection. 4: 991-997. PMID 12106793 DOI: 10.1016/S1286-4579(02)01618-0  0.475
2002 Scanga CA, Aliberti J, Jankovic D, Tilloy F, Bennouna S, Denkers EY, Medzhitov R, Sher A. Cutting edge: MyD88 is required for resistance to Toxoplasma gondii infection and regulates parasite-induced IL-12 production by dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 168: 5997-6001. PMID 12055206 DOI: 10.4049/Jimmunol.168.12.5997  0.502
2002 Aliberti J, Sher A. Positive and negative regulation of pathogen induced dendritic cell function by G-protein coupled receptors Molecular Immunology. 38: 891-893. PMID 12009566 DOI: 10.1016/S0161-5890(02)00015-9  0.41
2002 Jankovic D, Kullberg MC, Hieny S, Caspar P, Collazo CM, Sher A. In the absence of IL-12, CD4(+) T cell responses to intracellular pathogens fail to default to a Th2 pattern and are host protective in an IL-10(-/-) setting. Immunity. 16: 429-439. PMID 11911827 DOI: 10.1016/S1074-7613(02)00278-9  0.456
2001 Lighvani AA, Frucht DM, Jankovic D, Yamane H, Aliberti J, Hissong BD, Nguyen BV, Gadina M, Sher A, Paul WE, O'Shea JJ. T-bet is rapidly induced by interferon-gamma in lymphoid and myeloid cells. Proceedings of the National Academy of Sciences of the United States of America. 98: 15137-42. PMID 11752460 DOI: 10.1073/Pnas.261570598  0.434
2001 Aliberti J, Hieny S, Reis e Sousa C, Serhan CN, Sher A. Lipoxin-mediated inhibition of IL-12 production by DCs: a mechanism for regulation of microbial immunity. Nature Immunology. 3: 76-82. PMID 11743584 DOI: 10.1038/Ni745  0.445
2001 Marshall MA, Jankovic D, Ellen Maher V, Sher A, Berzofsky JA. Mice infected with Schistosoma mansoni develop a novel non-T-lymphocyte suppressor population which inhibits virus-specific CTL induction via a soluble factor Microbes and Infection. 3: 1051-1061. PMID 11709285 DOI: 10.1016/S1286-4579(01)01499-X  0.487
2001 Schaeffer EM, Yap GS, Lewis CM, Czar MJ, McVicar DW, Cheever AW, Sher A, Schwartzberg PL. Mutation of Tec family kinases alters T helper cell differentiation. Nature Immunology. 2: 1183-8. PMID 11702066 DOI: 10.1038/Ni734  0.399
2001 Jankovic D, Sher A, Yap G. Th1/Th2 effector choice in parasitic infection: decision making by committee. Current Opinion in Immunology. 13: 403-409. PMID 11498295 DOI: 10.1016/S0952-7915(00)00234-X  0.466
2001 Collazo CM, Yap GS, Sempowski GD, Lusby KC, Tessarollo L, Vande Woude GF, Sher A, Taylor GA. Inactivation of LRG-47 and IRG-47 reveals a family of interferon γ-inducible genes with essential, pathogen-specific roles in resistance to infection Journal of Experimental Medicine. 194: 181-187. PMID 11457893 DOI: 10.1084/Jem.194.2.181  0.491
2001 Czar MJ, Kersh EN, Mijares LA, Lanier G, Lewis J, Yap G, Chen A, Sher A, Duckett CS, Ahmed R, Schwartzberg PL. Altered lymphocyte responses and cytokine production in mice deficient in the X-linked lymphoproliferative disease gene SH2D1A/DSHP/SAP Proceedings of the National Academy of Sciences of the United States of America. 98: 7449-7454. PMID 11404475 DOI: 10.1073/Pnas.131193098  0.466
2001 Kullberg MC, Rothfuchs AG, Jankovic D, Caspar P, Wynn TA, Gorelick PL, Cheever AW, Sher A. Helicobacter hepaticus-induced colitis in interleukin-10-deficient mice: Cytokine requirements for the induction and maintenance of intestinal inflammation Infection and Immunity. 69: 4232-4241. PMID 11401959 DOI: 10.1128/Iai.69.7.4232-4241.2001  0.47
2001 Schito ML, Kennedy PE, Kowal RP, Berger EA, Sher A. A Human Immunodeficiency Virus–Transgenic Mouse Model for Assessing Interventions that Block Microbial-Induced Proviral Expression The Journal of Infectious Diseases. 183: 1592-1600. PMID 11343207 DOI: 10.1086/320716  0.401
2001 Yap GS, Ortmann R, Shevach E, Sher A. A heritable defect in IL-12 signaling in B10.Q/J mice. II. Effect on acute resistance to Toxoplasma gondii and rescue by IL-18 treatment Journal of Immunology. 166: 5720-5725. PMID 11313414 DOI: 10.4049/Jimmunol.166.9.5720  0.439
2001 Ortmann R, Smeltz R, Yap G, Sher A, Shevach EM. A Heritable Defect in IL-12 Signaling in B10.Q/J Mice. I. In Vitro Analysis Journal of Immunology. 166: 5712-5719. PMID 11313413 DOI: 10.4049/Jimmunol.166.9.5712  0.424
2001 Freitag C, Chougnet C, Schito M, Near KA, Shearer GM, Li C, Langhorne J, Sher A. Malaria infection induces virus expression in human immunodeficiency virus transgenic mice by CD4 T cell-dependent immune activation. The Journal of Infectious Diseases. 183: 1260-8. PMID 11262209 DOI: 10.1086/319686  0.461
2001 Chougnet C, Freitag C, Schito M, Thomas EK, Sher A, Shearer GM. In vivo CD40-CD154 (CD40 ligand) interaction induces integrated HIV expression by APC in an HIV-1-transgenic mouse model. Journal of Immunology (Baltimore, Md. : 1950). 166: 3210-7. PMID 11207274 DOI: 10.4049/Jimmunol.166.5.3210  0.381
2001 Kullberg MC, Jankovic D, Caspar P, Gorelick PL, Cheever A, Sher A. Bacteria-specific CD4+ T-cell clones induce colitis in helicobacter hepaticus-infected T-cell-deficient RAG-2 KO mice Gastroenterology. 120. DOI: 10.1016/S0016-5085(08)82580-2  0.423
2000 Schulz O, Edwards AD, Schito M, Aliberti J, Manickasingham S, Sher A, Sousa CRe. CD40 triggering of heterodimeric IL-12 p70 production by dendritic cells in vivo requires a microbial priming signal. Immunity. 13: 453-462. PMID 11070164 DOI: 10.1016/S1074-7613(00)00045-5  0.391
2000 Charest H, Sedegah M, Yap GS, Gazzinelli RT, Caspar P, Hoffman SL, Sher A. Recombinant attenuated Toxoplasma gondii expressing the Plasmodium yoelii circumsporozoite protein provides highly effective priming for CD8+ T cell-dependent protective immunity against malaria Journal of Immunology. 165: 2084-2092. PMID 10925293 DOI: 10.4049/Jimmunol.165.4.2084  0.484
2000 Aliberti J, Reis E Sousa C, Schito M, Hieny S, Wells T, Huffnagle GB, Sher A. CCR5 provides a signal for microbial induced production of IL-12 by CD8α+ dendritic cells Nature Immunology. 1: 83-87. PMID 10881180 DOI: 10.1038/76957  0.452
2000 Yap G, Pesin M, Sher A. Cutting Edge: IL-12 Is Required for the Maintenance of IFN-γ Production in T Cells Mediating Chronic Resistance to the Intracellular Pathogen, Toxoplasma gondii Journal of Immunology. 165: 628-631. PMID 10878333 DOI: 10.4049/Jimmunol.165.2.628  0.494
2000 Bundy D, Sher A, Michael E. Good Worms or Bad Worms: Do Worm Infections Affect the Epidemiological Patterns of Other Diseases? Parasitology Today. 16: 273-274. PMID 10858643 DOI: 10.1016/S0169-4758(00)01689-6  0.308
2000 Suzuki Y, Sher A, Yap G, Park D, Neyer LE, Liesenfeld O, Fort M, Kang H, Gufwoli E. IL-10 is required for prevention of necrosis in the small intestine and mortality in both genetically resistant BALB/c and susceptible C57BL/6 mice following peroral infection with Toxoplasma gondii. Journal of Immunology (Baltimore, Md. : 1950). 164: 5375-82. PMID 10799901 DOI: 10.4049/Jimmunol.164.10.5375  0.45
2000 Collazo CM, Miller C, Yap G, Hieny S, Caspar P, Schwartz RH, Sher A. Host resistance and immune deviation in pigeon cytochrome c T-cell receptor transgenic mice infected with Toxoplasma gondii. Infection and Immunity. 68: 2713-2719. PMID 10768964 DOI: 10.1128/Iai.68.5.2713-2719.2000  0.502
2000 Jankovic D, Kullberg MC, Noben-Trauth N, Caspar P, Paul WE, Sher A. Single cell analysis reveals that IL-4 receptor/Stat6 signaling is not required for the in vivo or in vitro development of CD4+ lymphocytes with a Th2 cytokine profile. Journal of Immunology (Baltimore, Md. : 1950). 164: 3047-55. PMID 10706693 DOI: 10.4049/Jimmunol.164.6.3047  0.446
2000 Taylor GA, Collazo CM, Yap GS, Nguyen K, Gregorio TA, Taylor LS, Eagleson B, Secrest L, Southon EA, Reid SW, Tessarollo L, Bray M, McVicar DW, Komschlies KL, Young HA, ... ... Sher A, et al. Pathogen-specific loss of host resistance in mice lacking the IFN-γ- inducible gene IGTP Proceedings of the National Academy of Sciences of the United States of America. 97: 751-755. PMID 10639151 DOI: 10.1073/Pnas.97.2.751  0.485
1999 Yap GS, Sher A. Cell-mediated immunity to Toxoplasma gondii: Initiation, regulation and effector function Immunobiology. 201: 240-247. PMID 10631573 DOI: 10.1016/S0171-2985(99)80064-3  0.51
1999 Sousa CRe, Yap G, Schulz O, Rogers N, Schito M, Aliberti J, Hieny S, Sher A. Paralysis of dendritic cell IL-12 production by microbial products prevents infection-induced immunopathology. Immunity. 11: 637-647. PMID 10591188 DOI: 10.1016/S1074-7613(00)80138-7  0.492
1999 Mountford AP, Coulson PS, Cheever AW, Sher A, Wilson RA, Wynn TA. Interleukin-12 can directly induce T-helper 1 responses in interferon- γ (IFN-γ) receptor-deficient mice, but requires IFN-γ signalling to downregulate T-helper 2 responses Immunology. 97: 588-594. PMID 10457211 DOI: 10.1046/J.1365-2567.1999.00832.X  0.456
1999 Sousa CRe, Sher A, Kaye P. The role of dendritic cells in the induction and regulation of immunity to microbial infection. Current Opinion in Immunology. 11: 392-399. PMID 10448137 DOI: 10.1016/S0952-7915(99)80066-1  0.413
1999 Liesenfeld O, Kang H, Park D, Nguyen TA, Parkhe CV, Watanabe H, Abo T, Sher A, Remington JS, Suzuki Y. TNF-alpha, nitric oxide and IFN-gamma are all critical for development of necrosis in the small intestine and early mortality in genetically susceptible mice infected perorally with Toxoplasma gondii. Parasite Immunology. 21: 365-76. PMID 10417671 DOI: 10.1046/J.1365-3024.1999.00237.X  0.439
1999 Montenegro SM, Miranda P, Mahanty S, Abath FG, Teixeira KM, Coutinho EM, Brinkman J, Gonçalves I, Domingues LA, Domingues AL, Sher A, Wynn TA. Cytokine production in acute versus chronic human Schistosomiasis mansoni: the cross-regulatory role of interferon-gamma and interleukin-10 in the responses of peripheral blood mononuclear cells and splenocytes to parasite antigens. The Journal of Infectious Diseases. 179: 1502-14. PMID 10228073 DOI: 10.1086/314748  0.436
1999 Schaeffer EM, Debnath J, Yap G, McVicar D, Liao XC, Littman DR, Sher A, Varmus HE, Lenardo MJ, Schwartzberg PL. Requirement for Tec kinases Rlk and Itk in T cell receptor signaling and immunity. Science (New York, N.Y.). 284: 638-41. PMID 10213685 DOI: 10.1126/Science.284.5414.638  0.35
1999 Yap GS, Sher A. Effector cells of both nonhemopoietic and hemopoietic origin are required for interferon (IFN)-γ- and tumor necrosis factor (TNF)-α- dependent host resistance to the intracellular pathogen, Toxoplasma gondii Journal of Experimental Medicine. 189: 1083-1091. PMID 10190899 DOI: 10.1084/Jem.189.7.1083  0.498
1999 Sher A, Hieny S, Charest H, Scharton-Kersten T, Collazo C, Germain RN, Reis e Sousa C. The role of dendritic cells in the initiation of host resistance to Toxoplasma gondii. Advances in Experimental Medicine and Biology. 452: 103-10. PMID 9889964 DOI: 10.1007/978-1-4615-5355-7_12  0.457
1999 Segal BH, Doherty TM, Wynn TA, Cheever AW, Sher A, Holland SM. The p47phox−/− Mouse Model of Chronic Granulomatous Disease Has Normal Granuloma Formation and Cytokine Responses to Mycobacterium avium and Schistosoma mansoni Eggs Infection and Immunity. 67: 1659-1665. DOI: 10.1128/Iai.67.4.1659-1665.1999  0.447
1998 Montenegro SM, Miranda P, Abath FG, Teixeira KM, Coutinho EM, Domingues AL, Domingues L, Brinkman J, Gonçalves I, Mahanty S, Sher A, Wynn TA. Preliminary results on the regulatory role of IFN-gamma and IL-10 human schistosomiasis mansoni. Memã³Rias Do Instituto Oswaldo Cruz. 93: 173. PMID 9921343 DOI: 10.1590/S0074-02761998000700027  0.445
1998 Cheever AW, Jankovic D, Yap GS, Kullberg MC, Sher A, Wynn TA. Role of Cytokines in the Formation and Down regulation of Hepatic Circumoval Granulomas and Hepatic Fibrosis in Schistosoma mansoni-Infected Mice Memorias Do Instituto Oswaldo Cruz. 93: 25-32. PMID 9921320 DOI: 10.1590/S0074-02761998000700004  0.517
1998 Kullberg MC, Ward JM, Gorelick PL, Caspar P, Hieny S, Cheever A, Jankovic D, Sher A. Helicobacter hepaticus triggers colitis in specific-pathogen-free interleukin-10 (IL-10)-deficient mice through an IL-12- and gamma interferon-dependent mechanism. Infection and Immunity. 66: 5157-66. PMID 9784517 DOI: 10.1128/Iai.66.11.5157-5166.1998  0.456
1998 Yap GS, Scharton-Kersten T, Ferguson DJP, Howe D, Suzuki Y, Sher A. Partially protective vaccination permits the development of latency in a normally virulent strain of Toxoplasma gondii Infection and Immunity. 66: 4382-4388. PMID 9712791 DOI: 10.1128/Iai.66.9.4382-4388.1998  0.371
1998 Sher A, Gazzinelli RT, Jankovic D, Scharton-Kersten T, Yap G, Doherty TM, Wynn T. Cytokines as determinants of disease and disease interactions. Brazilian Journal of Medical and Biological Research. 31: 85-87. PMID 9686183 DOI: 10.1590/S0100-879X1998000100011  0.474
1998 Oswald IP, Caspar P, Wynn TA, Scharton-Kersten T, Williams ME, Hieny S, Sher A, James SL. Failure of P strain mice to respond to vaccination against schistosomiasis correlates with impaired production of IL-12 and up-regulation of Th2 cytokines that inhibit macrophage activation. European Journal of Immunology. 28: 1762-72. PMID 9645357 DOI: 10.1002/(Sici)1521-4141(199806)28:06<1762::Aid-Immu1762>3.0.Co;2-J  0.451
1998 Jankovic D, Cheever AW, Kullberg MC, Wynn TA, Yap G, Caspar P, Lewis FA, Clynes R, Ravetch JV, Sher A. CD4+ T cell-mediated granulomatous pathology in schistosomiasis is downregulated by a B cell-dependent mechanism requiring Fc receptor signaling Journal of Experimental Medicine. 187: 619-629. PMID 9463412 DOI: 10.1084/Jem.187.4.619  0.454
1998 Doherty TM, Sher A, Vogel SN. Paclitaxel (Taxol)-Induced Killing ofLeishmania major in Murine Macrophages Infection and Immunity. 66: 4553-4556. DOI: 10.1128/Iai.66.9.4553-4556.1998  0.321
1997 Reis e Sousa C, Hieny S, Scharton-Kersten T, Jankovic D, Charest H, Germain RN, Sher A. In vivo microbial stimulation induces rapid CD40 ligand-independent production of interleukin 12 by dendritic cells and their redistribution to T cell areas. The Journal of Experimental Medicine. 186: 1819-29. PMID 9382881 DOI: 10.1084/Jem.186.11.1819  0.476
1997 Alexander J, Scharton-Kersten TM, Yap G, Roberts CW, Liew FY, Sher A. Mechanisms of innate resistance to Toxoplasma gondii infection Philosophical Transactions of the Royal Society B. 352: 1355-1359. PMID 9355127 DOI: 10.1098/Rstb.1997.0120  0.528
1997 Scharton-Kersten T, Contursi C, Masumi A, Sher A, Ozato K. Interferon consensus sequence binding protein-deficient mice display impaired resistance to intracellular infection due to a primary defect in interleukin 12 p40 induction Journal of Experimental Medicine. 186: 1523-1534. PMID 9348310 DOI: 10.1084/Jem.186.9.1523  0.484
1997 Gazzinelli RT, Camargo MM, Almeida IC, Morita YS, Giraldo M, Acosta-Serrano A, Hieny S, Englund PT, Ferguson MA, Travassos LR, Sher A. Identification and characterization of protozoan products that trigger the synthesis of IL-12 by inflammatory macrophages. Chemical Immunology. 68: 136-52. PMID 9329220 DOI: 10.1159/000058689  0.356
1997 Yap G, Cheever A, Caspar P, Jankovic D, Sher A. Unimpaired down-modulation of the hepatic granulomatous response in CD8 T-cell- and gamma interferon-deficient mice chronically infected with Schistosoma mansoni. Infection and Immunity. 65: 2583-6. PMID 9199423 DOI: 10.1128/Iai.65.7.2583-2586.1997  0.475
1997 Denkers EY, Sher A. Role of natural killer and NK1+ T-cells in regulating cell-mediated immunity during Toxoplasma gondii infection Biochemical Society Transactions. 25: 699-703. PMID 9191186 DOI: 10.1042/Bst0250699  0.44
1997 Wahl SM, Frazier-Jessen M, Jin WW, Kopp JB, Sher A, Cheever AW. Cytokine regulation of schistosome-induced granuloma and fibrosis. Kidney International. 51: 1370-5. PMID 9150446 DOI: 10.1038/Ki.1997.187  0.324
1997 Franzoso G, Carlson L, Scharton-Kersten T, Shores EW, Epstein S, Grinberg A, Tran T, Shacter E, Leonardi A, Anver M, Love P, Sher A, Siebenlist U. Critical roles for the Bcl-3 oncoprotein in T cell-mediated immunity, splenic microarchitecture, and germinal center reactions Immunity. 6: 479-490. PMID 9133427 DOI: 10.1016/S1074-7613(00)80291-5  0.409
1997 Scharton-Kersten TM, Yap G, Magram J, Sher A. Inducible Nitric Oxide Is Essential for Host Control of Persistent but Not Acute Infection with the Intracellular Pathogen Toxoplasma gondii Journal of Experimental Medicine. 185: 1261-1274. PMID 9104813 DOI: 10.1084/Jem.185.7.1261  0.485
1997 Scharton-Kersten TM, Sher A. Role of natural killer cells in innate resistance to protozoan infections. Current Opinion in Immunology. 9: 44-51. PMID 9039777 DOI: 10.1016/S0952-7915(97)80157-4  0.436
1997 Ahmed SF, Oswald IP, Caspar P, Hieny S, Keefer L, Sher A, James SL. Developmental differences determine larval susceptibility to nitric oxide-mediated killing in a murine model of vaccination against Schistosoma mansoni Infection and Immunity. 65: 219-226. PMID 8975915 DOI: 10.1128/Iai.65.1.219-226.1997  0.426
1996 Sher A, Jankovic D, Cheever A, Wynn T. An IL-12-based vaccine approach for preventing immunopathology in schistosomiasis. Annals of the New York Academy of Sciences. 795: 202-7. PMID 8958931 DOI: 10.1111/J.1749-6632.1996.Tb52669.X  0.446
1996 Scharton-Kersten T, Caspar P, Sher A, Denkers EY. Toxoplasma gondii: Evidence for interleukin-12-dependent and -independent pathways of interferon-γ production induced by an attenuated parasite strain Experimental Parasitology. 84: 102-114. PMID 8932760 DOI: 10.1006/Expr.1996.0096  0.507
1996 Abbas AK, Murphy KM, Sher A. Functional diversity of helper T lymphocytes Nature. 383: 787-793. PMID 8893001 DOI: 10.1038/383787A0  0.393
1996 Gazzinelli RT, Amichay D, Sharton-Kersten T, Grunwald E, Farber JM, Sher A. Role of macrophage-derived cytokines in the induction and regulation of cell-mediated immunity to Toxoplasma gondii. Current Topics in Microbiology and Immunology. 219: 127-39. PMID 8791695 DOI: 10.1007/978-3-642-51014-4_12  0.47
1996 Denkers EY, Scharton-Kersten T, Barbieri S, Caspar P, Sher A. A role for CD4+NK1.1+ T lymphocytes as major histocompatibility complex class II independent helper cells in the generation of CD8+ effector function against intracellular infection Journal of Experimental Medicine. 184: 131-139. PMID 8691126 DOI: 10.1084/Jem.184.1.131  0.467
1996 Gazzinelli RT, Sher A, Cheever A, Gerstberger S, Martin MA, Dickie P. Infection of human immunodeficiency virus 1 transgenic mice with Toxoplasma gondii stimulates proviral transcription in macrophages in vivo. The Journal of Experimental Medicine. 183: 1645-55. PMID 8666922 DOI: 10.1084/Jem.183.4.1645  0.375
1996 Chougnet C, Wynn TA, Clerici M, Landay AL, Kessler HA, Rusnak J, Melcher GP, Sher A, Shearer GM. Molecular analysis of decreased interleukin-12 production in persons infected with human immunodeficiency virus Journal of Infectious Diseases. 174: 46-53. PMID 8656012 DOI: 10.1093/Infdis/174.1.46  0.376
1996 Jankovic D, Sher A. Initiation and Regulation of CD4+ T-Cell Function in Host-Parasite Models Chemical Immunology. 63: 51-65. DOI: 10.1159/000425057  0.358
1995 Wynn TA, Sher A. IL 12 as an adjuvant for vaccines designed to prevent infection and immunopathology by schistosomes Research in Immunology. 146: 582-590. PMID 8839165 DOI: 10.1016/0923-2494(96)83035-5  0.353
1995 Scharton-Kersten T, Denkers EY, Gazzinelli R, Sher A. Role of IL 12 in induction of cell-mediated immunity to Toxoplasma gondii Research in Immunology. 146: 539-545. PMID 8839159 DOI: 10.1016/0923-2494(96)83029-X  0.441
1995 Sher A, Denkers EY, Gazzinelli RT. Induction and regulation of host cell-mediated immunity by Toxoplasma gondii Ciba Foundation Symposium. 195. PMID 8724832  0.428
1995 Cohn RG, Williams M, Sher A, Caulfield JP. Schistosoma mansoni: Characterization of an FcϵR+ Population of Granule-Containing Splenocytes Isolated from Infected Mice Experimental Parasitology. 80: 339-341. PMID 7895845 DOI: 10.1006/Expr.1995.1042  0.365
1995 Eltoum IA, Wynn TA, Poindexter RW, Finkelman FD, Lewis FA, Sher A, Cheever AW. Suppressive effect of interleukin-4 neutralization differs for granulomas around Schistosoma mansoni eggs injected into mice compared with those around eggs laid in infected mice Infection and Immunity. 63: 2532-2536. PMID 7790066 DOI: 10.1128/Iai.63.7.2532-2536.1995  0.38
1995 Fernandez-Botran R, Wynn TA, Hieny S, Caspar P, Chilton PM, Sher A. Linked in vivo expression of soluble interleukin-4 receptor and interleukin-4 in murine schistosomiasis European Journal of Immunology. 25: 649-656. PMID 7705393 DOI: 10.1002/Eji.1830250304  0.398
1995 Wynn TA, Cheever AW, Jankovic D, Poindexter RW, Caspar P, Lewis FA, Sher A. An IL-12-based vaccination method for preventing fibrosis induced by schistosome infection Nature. 376: 594-596. PMID 7637808 DOI: 10.1038/376594A0  0.44
1995 Epstein MM, Rosa FD, Jankovic D, Sher A, Matzinger P. Successful T cell priming in B cell-deficient mice. Journal of Experimental Medicine. 182: 915-922. PMID 7561694 DOI: 10.1084/Jem.182.4.915  0.366
1995 Sher A, Ahmed R. Regulation of innate and adaptive responses to infection: new avenues and angles Current Opinion in Immunology. 7: 471-473. DOI: 10.1016/0952-7915(95)80090-5  0.36
1994 Carrera L, Chiaramonte M, Kuhn R, Muller W, Sacks D, Sher A, Gazzinelli RT. Leishmania major and Toxoplasma gondii have opposite effects on cytokine synthesis by macrophages. MemóRias Do Instituto Oswaldo Cruz. 89: 649-50. PMID 8524067 DOI: 10.1590/S0074-02761994000400024  0.366
1994 Clerici M, Wynn TA, Berzofsky JA, Blatt SP, Hendrix CW, Sher A, Coffman RL, Shearer GM. Role of interleukin-10 in T helper cell dysfunction in asymptomatic individuals infected with the human immunodeficiency virus Journal of Clinical Investigation. 93: 768-775. PMID 8113410 DOI: 10.1172/Jci117031  0.422
1994 Denkers EY, Caspar P, Sher A. Toxoplasma gondii possesses a superantigen activity that selectively expands murine T cell receptor Vβ5-bearing CD8+ lymphocytes Journal of Experimental Medicine. 180: 985-994. PMID 8064244 DOI: 10.1084/Jem.180.3.985  0.458
1994 Nara T, Matsumoto N, Janecharut T, Matsuda H, Yamamoto K, Irimura T, Nakamura K, Alkawa M, Oswald I, Sher A, Kita K, Kojima S. Demonstration of the target molecule of a protective IgE antibody in secretory glands of Schistosoma japonicum larvae. International Immunology. 6: 963-971. PMID 7947464 DOI: 10.1093/Intimm/6.7.963  0.314
1994 Williams ME, Montenegro S, Domingues AL, Wynn TA, Teixeira K, Mahanty S, Coutinho A, Sher A. Leukocytes of patients with Schistosoma mansoni respond with a Th2 pattern of cytokine production to mitogen or egg antigens but with a Th0 pattern to worm antigens. The Journal of Infectious Diseases. 170: 946-54. PMID 7930740 DOI: 10.1093/Infdis/170.4.946  0.475
1994 Wynn TA, Eltoum I, Oswald IP, Cheever AW, Sher A. Endogenous interleukin 12 (IL-12) regulates granuloma formation induced by eggs of Schistosoma mansoni and exogenous IL-12 both inhibits and prophylactically immunizes against egg pathology Journal of Experimental Medicine. 179: 1551-1561. PMID 7909326 DOI: 10.1084/Jem.179.5.1551  0.448
1994 Actor JK, Marshall MA, Eltoum IA, Buller RML, Berzofsky JA, Sher A. Increased susceptibility of mice infected with Schistosoma mansoni to recombinant vaccinia virus: Association of viral persistence with egg granuloma formation European Journal of Immunology. 24: 3050-3056. PMID 7805733 DOI: 10.1002/Eji.1830241220  0.41
1994 Viana IR, Sher A, Carvalho OS, Massara CL, Eloi-Santos SM, Pearce EJ, Colley DG, Gazzinelli G, Correa-Oliveira R. Interferon-gamma production by peripheral blood mononuclear cells from residents of an area endemic for Schistosoma mansoni. Transactions of the Royal Society of Tropical Medicine and Hygiene. 88: 466-70. PMID 7570847 DOI: 10.1016/0035-9203(94)90436-7  0.432
1994 Oswald IP, Wynn TA, Sher A, James SL. NO as an affector molecule of parasite killing: modulation of its synthesis by cytokines Comparative Biochemistry and Physiology. Part C: Pharmacology. 108: 11-18. PMID 7520338 DOI: 10.1016/1367-8280(94)90083-3  0.472
1994 Oswald IP, Eltoum I, Wynn TA, Schwartz B, Caspar P, Paulin D, Sher A, James SL. Endothelial cells are activated by cytokine treatment to kill an intravascular parasite, Schistosoma mansoni, through the production of nitric oxide Proceedings of the National Academy of Sciences of the United States of America. 91: 999-1003. PMID 7508126 DOI: 10.1073/Pnas.91.3.999  0.439
1993 Williams ME, Kullberg MC, Barbieri S, Caspar P, Berzofsky JA, Seder RA, Sher A. Fc epsilon receptor-positive cells are a major source of antigen-induced interleukin-4 in spleens of mice infected with Schistosoma mansoni. European Journal of Immunology. 23: 1910-6. PMID 8344353 DOI: 10.1002/Eji.1830230827  0.5
1993 Oswald IP, Wynn TA, Williams ME, Eltoum I, Cheever AW, James SL, Sher A. Regulatory and immunopathological roles of IL4 in experimental schistosomiasis. Research in Immunology. 144: 643-8. PMID 8303083 DOI: 10.1016/S0923-2494(05)80020-3  0.339
1993 Denkers EY, Gazzinelli RT, Martin D, Sher A. Emergence of NK1.1+ cells as effectors of IFN-γ dependent immunity to Toxoplasma gondii in MHC class I-deficient mice Journal of Experimental Medicine. 178: 1465-1472. PMID 8228800 DOI: 10.1084/Jem.178.5.1465  0.467
1993 Gazzinelli RT, Hieny S, Wynn TA, Wolf S, Sher A. Interleukin 12 is required for the T-lymphocyte-independent induction of interferon γ by an intracellular parasite and induces resistance in T-cell- deficient hosts Proceedings of the National Academy of Sciences of the United States of America. 90: 6115-6119. PMID 8100999 DOI: 10.1073/Pnas.90.13.6115  0.503
1993 Cheever AW, Xu Y, Sher A, Finkelman FD, Cox TM, Macedonia JG. Schistosoma japonicum-infected mice show reduced hepatic fibrosis and eosinophilia and selective inhibition of interleukin-5 secretion by CD4+ cells after treatment with anti-interleukin-2 antibodies. Infection and Immunity. 61: 1288-92. PMID 8095922 DOI: 10.1128/Iai.61.4.1288-1292.1993  0.425
1993 Denkers EY, Sher A, Gazzinelli RT. CD8+ T-cell interactions with Toxoplasma gondii: implications for processing of antigen for class-I-restricted recognition Research in Immunology. 144: 51-57. PMID 8095730 DOI: 10.1016/S0923-2494(05)80099-9  0.39
1993 Actor JK, Shirai M, Kullberg MC, Buller RML, Sher A, Berzofsky JA. Helminth infection results in decreased virus-specific CD8+ cytotoxic T-cell and Th1 cytokine responses as well as delayed virus clearance Proceedings of the National Academy of Sciences of the United States of America. 90: 948-952. PMID 8094248 DOI: 10.1073/Pnas.90.3.948  0.472
1993 Seder RA, Gazzinelli R, Sher A, Paul WE. Interleukin 12 acts directly on CD4+ T cells to enhance priming for interferon gamma production and diminishes interleukin 4 inhibition of such priming. Proceedings of the National Academy of Sciences of the United States of America. 90: 10188-92. PMID 7901851 DOI: 10.1073/Pnas.90.21.10188  0.43
1993 Murphy E, Hieny S, Sher A, O'Garra A. Detection of in vivo expression of interleukin-10 using a semi-quantitative polymerase chain reaction method in Schistosoma mansoni infected mice Journal of Immunological Methods. 162: 211-223. PMID 7686199 DOI: 10.1016/0022-1759(93)90386-L  0.367
1992 Sher A, Coffman RL. Regulation of immunity to parasites by T cells and T cell-derived cytokines Annual Review of Immunology. 10: 385-409. PMID 1590992 DOI: 10.1146/ANNUREV.IY.10.040192.002125  0.377
1992 Sher A. Parasitizing the cytokine system Nature. 356: 565-566. PMID 1560840 DOI: 10.1038/356565A0  0.376
1992 Oswald IP, Wynn TA, Sher A, James SL. Interleukin 10 inhibits macrophage microbicidal activity by blocking the endogenous production of tumor necrosis factor α required as a costimulatory factor for interferon γ-induced activation Proceedings of the National Academy of Sciences of the United States of America. 89: 8676-8680. PMID 1528880 DOI: 10.1073/Pnas.89.18.8676  0.376
1992 Gazzinelli RT, Oswald IP, Hieny S, James SL, Sher A. The microbicidal activity of interferon‐γ‐treated macrophages against Trypanosoma cruzi involves an L‐arginine‐dependent, nitrogen oxide‐mediated mechanism inhibitable by interleukin‐10 and transforming growth factor‐β European Journal of Immunology. 22: 2501-2506. PMID 1396957 DOI: 10.1002/Eji.1830221006  0.41
1992 Sher A, Gazzinelli RT, Oswald IP, Clerici M, Kullberg M, Pearce EJ, Berzofsky JA, Mosmann TR, James SL, Morse HC, Shearer GM. Role of T-cell derived cytokines in the downregulation of immune responses in parasitic and retroviral infection Immunological Reviews. 183-204. PMID 1354651 DOI: 10.1111/J.1600-065X.1992.Tb01414.X  0.531
1992 Cheever AW, Xu Y, Macedonia JG, Cox T, Hieny S, Sher A. The role of cytokines in the pathogenesis of hepatic granulomatous disease in Schistosoma mansoni infected mice. Memã³Rias Do Instituto Oswaldo Cruz. 87: 81-5. PMID 1343930 DOI: 10.1590/S0074-02761992000800011  0.434
1992 Gazzinelli RT, Hartley JW, Fredrickson TN, Chattopadhyay SK, Sher A, Morse HC. Opportunistic infections and retrovirus-induced immunodeficiency: studies of acute and chronic infections with Toxoplasma gondii in mice infected with LP-BM5 murine leukemia viruses. Infection and Immunity. 60: 4394-401. PMID 1328058 DOI: 10.1128/Iai.60.10.4394-4401.1992  0.473
1991 Cheever AW, Xu YH, Sher A, Macedonia JG. Analysis of egg granuloma formation in Schistosoma japonicum-infected mice treated with antibodies to interleukin-5 and gamma interferon. Infection and Immunity. 59: 4071-4. PMID 1834572 DOI: 10.1128/Iai.59.11.4071-4074.1991  0.463
1991 Finkelman FD, Pearce EJ, Urban JF, Sher A. Regulation and biological function of helminth-induced cytokine responses Immunology Today. 12. PMID 1829892 DOI: 10.1016/S0167-5699(05)80018-0  0.476
1991 Pearce EJ, Caspar P, Grzych JM, Lewis FA, Sher A. Downregulation of Th1 cytokine production accompanies induction of Th2 responses by a parasitic helminth, Schistosoma mansoni. The Journal of Experimental Medicine. 173: 159-66. PMID 1824635 DOI: 10.1084/Jem.173.1.159  0.51
1991 Pearce EJ, Sher A. Functional dichotomy in the CD4+T cell response to Schistosoma mansoni Experimental Parasitology. 73: 110-116. PMID 1711476 DOI: 10.1016/0014-4894(91)90014-N  0.321
1991 Mosmann TR, Schumacher JH, Street NF, Budd R, O'Garra A, Fong TA, Bond MW, Moore KW, Sher A, Fiorentino DF. Diversity of cytokine synthesis and function of mouse CD4+ T cells. Immunological Reviews. 123: 209-29. PMID 1684780 DOI: 10.1111/J.1600-065X.1991.Tb00612.X  0.345
1991 Xu YH, Macedonia J, Sher A, Pearce E, Cheever AW. Dynamic analysis of splenic Th1 and Th2 lymphocyte functions in mice infected with Schistosoma japonicum. Infection and Immunity. 59: 2934-40. PMID 1679041 DOI: 10.1128/Iai.59.9.2934-2940.1991  0.492
1991 Finkelman FD, Pearce EJ, Urban JF, Sher A. Regulation and biological function of helminth-induced cytokine responses Parasitology Today. 7: 62-66. DOI: 10.1016/0169-4758(91)90035-M  0.474
1990 Scott P, Pearce E, Cheever AW, Coffman RL, Sher A. Role of cytokines and CD4+ T-cell subsets in the regulation of parasite immunity and disease. Immunological Reviews. 112: 161-82. PMID 2575073 DOI: 10.1111/J.1600-065X.1989.Tb00557.X  0.512
1990 Pearce EJ, Sher A. Immunity to helminths Current Opinion in Immunology. 2: 375-379. PMID 2534502 DOI: 10.1016/0952-7915(89)90144-1  0.346
1990 James SL, Sher A. Cell-mediated immune response to schistosomiasis Current Topics in Microbiology and Immunology. 155: 21-31. PMID 2407432 DOI: 10.1007/978-3-642-74983-4_2  0.362
1990 Sher A, Coffman RL, Hieny S, Scott P, Cheever AW. Interleukin 5 is required for the blood and tissue eosinophilia but not granuloma formation induced by infection with Schistosoma mansoni. Proceedings of the National Academy of Sciences of the United States of America. 87: 61-5. PMID 2104985 DOI: 10.1073/Pnas.87.1.61  0.478
1989 Scott P, Natovitz P, Coffman RL, Pearce E, Sher A. CD4+ T cell subsets in experimental cutaneous leishmaniasis. Memorias Do Instituto Oswaldo Cruz. 256-9. PMID 3267029 DOI: 10.1590/S0074-02761988000500006  0.304
1989 James SL, Pearce EJ, Sher A. Prospects for a nonliving vaccine against schistosomiasis based on cell-mediated immune resistance mechanisms. Memorias Do Instituto Oswaldo Cruz. 121-3. PMID 3151085 DOI: 10.1590/S0074-02761987000800020  0.467
1989 Correa-Oliveira R, Pearce EJ, Oliveira GC, Golgher DB, Katz N, Bahia LG, Carvalho OS, Gazzinelli G, Sher A. The human immune response to defined immunogens of Schistosoma mansoni: elevated antibody levels to paramyosin in stool-negative individuals from two endemic areas in Brazil. Transactions of the Royal Society of Tropical Medicine and Hygiene. 83: 798-804. PMID 2617649 DOI: 10.1016/0035-9203(89)90334-9  0.332
1989 Sher A, James SL, Correa-Oliveira R, Hieny S, Pearce E. Schistosome vaccines: current progress and future prospects. Parasitology. S61-8. PMID 2498828 DOI: 10.1017/S0031182000072255  0.341
1989 Brindley PJ, Strand M, Norden AP, Sher A. Role of host antibody in the chemotherapeutic action of praziquantel against Schistosoma mansoni: identification of target antigens. Molecular and Biochemical Parasitology. 34: 99-108. PMID 2496307 DOI: 10.1016/0166-6851(89)90001-7  0.331
1988 Rimoldi MT, Sher A, Heiny S, Lituchy A, Hammer CH, Joiner K. Developmentally regulated expression by Trypanosoma cruzi of molecules that accelerate the decay of complement C3 convertases. Proceedings of the National Academy of Sciences of the United States of America. 85: 193-7. PMID 3277170 DOI: 10.1073/Pnas.85.1.193  0.316
1988 Sher A, James S. Genetic control of vaccine-induced immunity against a parasitic helminth, Schistosoma mansoni Bioessays. 9: 163-166. PMID 3149197 DOI: 10.1002/Bies.950090506  0.427
1988 Pearce EJ, James SL, Hieny S, Lanar DE, Sher A. Induction of protective immunity against Schistosoma mansoni by vaccination with schistosome paramyosin (Sm97), a nonsurface parasite antigen. Proceedings of the National Academy of Sciences of the United States of America. 85: 5678-82. PMID 3135553 DOI: 10.1073/Pnas.85.15.5678  0.455
1988 Correa-Oliveira R, James SL, Sher A. Genetic complementation of defects in vaccine-induced immunity against Schistosoma mansoni in P- and A-strain inbred mice. Infection and Immunity. 56: 708-10. PMID 3125113 DOI: 10.1128/Iai.56.3.708-710.1988  0.374
1988 Scott P, Natovitz P, Coffman RL, Pearce E, Sher A. Immunoregulation of cutaneous leishmaniasis. T cell lines that transfer protective immunity or exacerbation belong to different T helper subsets and respond to distinct parasite antigens. The Journal of Experimental Medicine. 168: 1675-84. PMID 2903212 DOI: 10.1084/Jem.168.5.1675  0.469
1987 Pearce EJ, Zilberstein D, James SL, Sher A. Kinetic correlation of the acquisition of resistance to immune attack in schistosomula of Schistosoma mansoni with a developmental change in membrane potential. Molecular and Biochemical Parasitology. 21: 259-67. PMID 3807946 DOI: 10.1016/0166-6851(86)90131-3  0.317
1987 Scott P, Pearce E, Heath S, Sher A. Identification of T-cell-reactive antigens that protect BALB/c mice against Leishmania major. Annales De L'Institut Pasteur. Immunologie. 138: 771-774. PMID 3501959 DOI: 10.1016/S0769-2625(87)80036-3  0.378
1987 Brindley PJ, Sher A. Anti-schistosomal drugs: observations on the mechanism of drug resistance to hycanthone, and on the involvement of host antibodies in the mode of action of praziquantel Memorias Do Instituto Oswaldo Cruz. 82: 157-161. PMID 3151089 DOI: 10.1590/S0074-02761987000800027  0.303
1987 James SL, Correa-Oliveira R, Sher A, Medvitz LA, McCall RD. Genetic association of defects in macrophage larvicidal activity and vaccine-induced resistance to Schistosoma mansoni in P strain mice. Infection and Immunity. 55: 1884-1889. PMID 3112016 DOI: 10.1128/Iai.55.8.1884-1889.1987  0.379
1987 Sher A, Correa-Oliveira R, Brindley P, James SL. Selection of the host for resistance: genetic control of protective immunity to schistosomes. International Journal For Parasitology. 17: 53-7. PMID 3108177 DOI: 10.1016/0020-7519(87)90026-9  0.404
1986 Lanar DE, Pearce EJ, James SL, Sher A. Identification of paramyosin as schistosome antigen recognized by intradermally vaccinated mice. Science (New York, N.Y.). 234: 593-6. PMID 3094144 DOI: 10.1126/Science.3094144  0.313
1986 Joiner K, Sher A, Gaither T, Hammer C. Evasion of alternative complement pathway by Trypanosoma cruzi results from inefficient binding of factor B. Proceedings of the National Academy of Sciences of the United States of America. 83: 6593-6597. PMID 2944112 DOI: 10.1073/Pnas.83.17.6593  0.325
1986 Pearce EJ, Basch PF, Sher A. Evidence that the reduced surface antigenicity of developing Schistosoma mansoni schistosomula is due to antigen shedding rather than host molecule acquisition. Parasite Immunology. 8: 79-94. PMID 2421228 DOI: 10.1111/J.1365-3024.1986.Tb00835.X  0.352
1985 Von Lichtenberg F, Correa-Oliveira R, Sher A. The fate of challenge schistosomula in the murine anti-schistosome vaccine model. The American Journal of Tropical Medicine and Hygiene. 34: 96-106. PMID 3970313 DOI: 10.4269/Ajtmh.1985.34.96  0.384
1985 Lewis FA, Hieny S, Sher A. Evidence against the existence of specific Schistosoma mansoni subpopulations which are resistant to irradiated vaccine-induced immunity. American Journal of Tropical Medicine and Hygiene. 34: 86-91. PMID 3970312 DOI: 10.4269/Ajtmh.1985.34.86  0.418
1985 Correa-Oliveira R, Sher A. Defective immunoglobulin M responses to vaccination or infection with Schistosoma mansoni in xid mice Infection and Immunity. 50: 409-414. PMID 3932208 DOI: 10.1128/Iai.50.2.409-414.1985  0.338
1985 Cheever AW, Byram JE, Hieny S, Lichtenberg F, Lunde MN, Sher A. Immunopathology of Schistosoma japonicum and S. mansoni infection in B cell depleted mice. Parasite Immunology. 7: 399-413. PMID 3875829 DOI: 10.1111/J.1365-3024.1985.Tb00086.X  0.411
1985 Scott P, James S, Sher A. The respiratory burst is not required for killing of intracellular and extracellular parasites by a lymphokine-activated macrophage cell line European Journal of Immunology. 15: 553-558. PMID 2988973 DOI: 10.1002/Eji.1830150605  0.334
1985 Lanar DE, Pearce EJ, Sher A. Expression in Escherichia coli of two Schistosoma mansoni genes that encode major antigens recognized by immune mice. Molecular and Biochemical Parasitology. 17: 45-60. PMID 2414657 DOI: 10.1016/0166-6851(85)90127-6  0.348
1984 Correa-Oliveira R, Sher A, James SL. Mechanisms of protective immunity against Schistosoma mansoni infection in mice vaccinated with irradiated cercariae. V. Anamnestic cellular and humoral responses following challenge infection. The American Journal of Tropical Medicine and Hygiene. 33: 261-8. PMID 6711743 DOI: 10.4269/Ajtmh.1984.33.261  0.409
1984 Sher A, Hieny S, James S. Mechanisms of protective immunity against 5. mansoni infection in mice vaccinated with irradiated cercariae. VI. Influence of the major histocompatibility complex Parasite Immunology. 6: 319-328. PMID 6472878 DOI: 10.1111/J.1365-3024.1984.Tb00804.X  0.361
1984 Sher A, Sacks DL, Simpson AJ, Singer A. Dichotomy in the tissue origin of schistosome acquired class I and class II major histocompatibility complex antigens. The Journal of Experimental Medicine. 159: 952-7. PMID 6366108 DOI: 10.1084/Jem.159.3.952  0.318
1983 Cheever AW, Hieny S, Duvall RH, Sher A. Lack of resistance to Schistosoma japonicum in mice immunized with irradiated S. mansoni cercariae. Transactions of the Royal Society of Tropical Medicine and Hygiene. 77: 812-4. PMID 6665834 DOI: 10.1016/0035-9203(83)90295-X  0.332
1983 James SL, Sher A. Mechanisms of protective immunity against Schistosoma mansoni infection in mice vaccinated with irradiated cercariae. III. Identification of a mouse strain, P/N, that fails to respond to vaccination Parasite Immunology. 5: 567-575. PMID 6657295 DOI: 10.1111/J.1365-3024.1983.Tb00773.X  0.36
1983 Simpson AJ, James SL, Sher A. Identification of surface antigens of schistosomula of Schistosoma mansoni recognized by antibodies from mice immunized by chronic infection and by exposure to highly irradiated cercariae. Infection and Immunity. 41: 591-597. PMID 6347891 DOI: 10.1128/Iai.41.2.591-597.1983  0.384
1983 Sher A, Sacks DL, Scott PA. Host and parasite factors influencing the expression of cutaneous leishmaniasis. Ciba Foundation Symposium. 99: 174-89. PMID 6227463  0.34
1982 Sher A, Benno D. Decreasing immunogenicity of developing schistosome larvae Parasite Immunology. 4: 101-107. PMID 7070833 DOI: 10.1111/J.1365-3024.1982.Tb00423.X  0.331
1982 Sacks DL, Esser KM, Sher A. Immunization of mice against African trypanosomiasis using anti-idiotypic antibodies. The Journal of Experimental Medicine. 155: 1108-19. PMID 6977615 DOI: 10.1084/Jem.155.4.1108  0.399
1982 Sher A, Snary D. Specific inhibition of the morphogenesis of Trypanosoma cruzi by a monoclonal antibody Nature. 300: 639-640. PMID 6755270 DOI: 10.1038/300639A0  0.375
1982 James SL, Lazdins JK, Meltzer MS, Sher A. Macrophages as effector cells of protective immunity in murine schistosomiasis: I. Activation of peritoneal macrophages during natural infection Cellular Immunology. 67: 255-266. PMID 6282469 DOI: 10.1016/0008-8749(82)90218-0  0.478
1982 James SL, Kipnis TL, Sher A, Hoff R. Enhanced resistance to acute infection with Trypanosoma cruzi in mice treated with an interferon inducer. Infection and Immunity. 35: 588-593. PMID 6173326 DOI: 10.1128/Iai.35.2.588-593.1982  0.458
1981 Miller KL, Smithers SR, Sher A. The response of mice immune to Schistosoma mansoni to a challenge infection which bypasses the skin: Evidence for two mechanisms of immunity Parasite Immunology. 3: 25-31. PMID 7012761 DOI: 10.1111/J.1365-3024.1981.Tb00382.X  0.441
1981 James SL, Labine M, Sher A. Mechanisms of protective immunity against Schistosoma mansoni infection in mice vaccinated with irradiated cercariae. I. Analysis of antibody and T-lymphocyte responses in mouse strains developing differing levels of immunity. Cellular Immunology. 65: 75-83. PMID 6976215 DOI: 10.1016/0008-8749(81)90053-8  0.397
1981 Kipnis TL, James SL, Sher A, David JR. Cell-mediated cytotoxicity to Trypanosoma cruzi. II. Antibody-dependent killing of bloodstream forms by mouse eosinophils and neutrophils. American Journal of Tropical Medicine and Hygiene. 30: 47-53. DOI: 10.4269/Ajtmh.1981.30.47  0.359
1981 Moser G, Lichtenberg Fv, Sher A. Studies of the antibody-dependent killing of schistosomula of Schistosoma mansoni employing haptenic target antigens. Analysis of mechanisms responsible for the rejection of parasites in vivo. Parasitology. 83: 543-558. DOI: 10.1017/S0031182000080525  0.305
1979 James SL, Leid RW, Sher A. Purification of rodent eosinophils on discontinuous metrizamide gradients Journal of Immunological Methods. 27: 373-382. PMID 469262 DOI: 10.1016/0022-1759(79)90214-X  0.351
1979 Vadas MA, Butterworth AE, Burakoff S, Sher A. Major histocompatibility complex products restrict the adherence of cytolytic T lymphocytes to minor histocompatibility antigens or to trinitrophenyl determinants on schistosomula of Schistosoma mansoni. Proceedings of the National Academy of Sciences of the United States of America. 76: 1982-1985. PMID 88051 DOI: 10.1073/Pnas.76.4.1982  0.323
1978 Imohiosen EAE, Sher A, Lichtenberg FV. Early developmental changes of the schistosomula of Schistosoma mansoni in vitro and in mouse lung. Parasitology. 76: 317-326. PMID 662413 DOI: 10.1017/S0031182000048198  0.347
1978 Sher A, Hall BF, Vadas MA. Acquisition of murine major histocompatibility complex gene products by schistosomula of schistosoma mansoni. Journal of Experimental Medicine. 148: 46-57. PMID 97360 DOI: 10.1084/Jem.148.1.46  0.371
1977 Sher A, McIntyre S, Lichtenberg Fv. Schistosoma mansoni: kinetics and class specificity of hypergammaglobulinemia induced during murine infection. Experimental Parasitology. 41: 415-422. PMID 849767 DOI: 10.1016/0014-4894(77)90114-X  0.389
1977 Sher A, Smithers SR, MacKenzie P, Broomfield K. Schistosoma mansoni: Immunoglobulins involved in passive immunization of laboratory mice Experimental Parasitology. 41: 160-166. PMID 838027 DOI: 10.1016/0014-4894(77)90141-2  0.363
1977 Sher A. Immunity against Schistosoma mansoni in the mouse American Journal of Tropical Medicine and Hygiene. 26: 20-28. PMID 596522 DOI: 10.4269/Ajtmh.1977.26.20  0.375
1977 Goldring OL, Sher A, Smithers SR, McLaren DJ. Host antigens and parasite antigens of murine Schistosoma mansoni. Transactions of the Royal Society of Tropical Medicine and Hygiene. 71: 144-148. PMID 327628 DOI: 10.1016/0035-9203(77)90083-9  0.365
1976 Sher A. Complement-dependent adherence of mast cells to schistosomula Nature. 263: 334-336. PMID 958490 DOI: 10.1038/263334A0  0.429
1975 Sher A, Smithers SR, Mackenzie P. Passive transfer of acquired resistance to Schistosoma mansoni in laboratory mice. Parasitology. 70: 347-358. PMID 1134831 DOI: 10.1017/S0031182000052124  0.419
1974 Sher A, Mackenzie P, Smithers SR. Decreased Recovery of Invading Parasites from the Lungs as a Parameter of Acquired Immunity to Schistosomiasis in the Mouse The Journal of Infectious Diseases. 130: 626-633. PMID 4427079 DOI: 10.1093/Infdis/130.6.626  0.379
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