John Fielding Kellie - Publications

Affiliations: 
2012 Chemistry Northwestern University, Evanston, IL 

27 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Schneck NA, Mehl JT, Kellie JF. Protein LC-MS Tools for the Next Generation of Biotherapeutic Analyses from Preclinical and Clinical Serum. Journal of the American Society For Mass Spectrometry. PMID 37478497 DOI: 10.1021/jasms.3c00064  0.577
2022 Carle K, Kellie JF, Gunn GR, Jiang Y. Determination of label efficiency and label degree of critical reagents by LC-MS and native MS. Analytical Biochemistry. 115033. PMID 36584741 DOI: 10.1016/j.ab.2022.115033  0.439
2022 Kellie JF, Schneck NA, Causon JC, Baba T, Mehl JT, Pohl KI. Top-Down Characterization and Intact Mass Quantitation of a Monoclonal Antibody Drug from Serum by Use of a Quadrupole TOF MS System Equipped with Electron-Activated Dissociation. Journal of the American Society For Mass Spectrometry. PMID 36459688 DOI: 10.1021/jasms.2c00206  0.514
2022 An B, Sikorsiki T, Kellie JF, Chen Z, Schneck NA, Mehl J, Tang H, Qu J, Shi T, Gao Y, Jacobs JM, Nandita E, van Soest R, Jones E. An antibody-free platform for multiplexed, sensitive quantification of protein biomarkers in complex biomatrices. Journal of Chromatography. A. 1676: 463261. PMID 35752151 DOI: 10.1016/j.chroma.2022.463261  0.588
2020 Kellie JF, Alelyunas YW, Albert J, Schneck NA, Chen Z, Sychterz CJ, Edwards I, Shion H, Wrona MD, Szapacs ME. Intact mAb LC-MS for drug concentration from pre-clinical studies: bioanalytical method performance and in-life samples. Bioanalysis. PMID 32975433 DOI: 10.4155/bio-2020-0168  0.553
2020 Kellie JF, Tran JC, Jian W, Jones BR, Mehl JT, Ge Y, Henion J, Bateman KP. Intact Protein Mass Spectrometry for Therapeutic Protein Quantitation, Pharmacokinetics and Biotransformation in Pre-Clinical and Clinical Studies: An Industry Perspective. Journal of the American Society For Mass Spectrometry. PMID 32869982 DOI: 10.1021/Jasms.0C00270  0.63
2020 Chen Z, Kellie JF, Hottenstein CS, Szapacs ME. Native high-resolution mass spectrometry analysis of noncovalent protein complexes up to 450 kDa. Bioanalysis. PMID 32830519 DOI: 10.4155/Bio-2020-0145  0.692
2020 Kellie JF, Pannullo KE, Li YB, Fraley KJ, Mayer AP, Sychterz CJ, Szapacs ME, Karlinsey MZ. Antibody Subunit LC-MS Analysis for Pharmacokinetic and Biotransformation Determination from In-Life Studies for Complex Biotherapeutics. Analytical Chemistry. PMID 32392410 DOI: 10.1021/Acs.Analchem.0C00520  0.421
2019 Fandozzi C, Evans C, Wilson A, Su D, Anderson M, Clausen V, Dillen L, Garofolo F, Holliman C, Nickbarg E, Olah T, Ramanathan R, Zhang H, Kaur S, Pillutla R, ... ... Kellie J, et al. 2019 White Paper on Recent Issues in Bioanalysis: Chromatographic Assays (Part 1 - Innovation in Small Molecules and Oligonucleotides & Mass Spectrometric Method Development Strategies for Large Molecule Bioanalysis). Bioanalysis. 2029-2048. PMID 31808716 DOI: 10.4155/Bio-2019-0260  0.343
2019 Kellie JF, Sikorski TW, An B, Chen Z, Moghieb AH, Busz MG, Szapacs ME, Angel TE. A new era for proteomics. Bioanalysis. PMID 31617394 DOI: 10.4155/Bio-2019-0191  0.383
2019 Kellie JF. Intact protein LC–MS for pharmacokinetics International Journal of Pharmacokinetics. 4: IPK05. DOI: 10.4155/ipk-2020-0004  0.557
2018 Kellie JF, Thomson AS, Chen S, Childs SL, Karlinsey MZ, Mai SH, White JR, Biddlecombe RA. Biotherapeutic Antibody Subunit LC-MS and Peptide Mapping LC-MS Measurements to Study Possible Biotransformation and Critical Quality Attributes In Vivo. Journal of Pharmaceutical Sciences. PMID 30465782 DOI: 10.1016/J.Xphs.2018.11.019  0.475
2018 Kellie JF, Karlinsey MZ. Review of approaches and examples for monitoring biotransformation in protein and peptide therapeutics by MS. Bioanalysis. PMID 30325207 DOI: 10.4155/Bio-2018-0113  0.541
2017 Kellie JF, Kehler JR, Karlinsey MZ, Summerfield SG. Toward best practices in data processing and analysis for intact biotherapeutics by MS in quantitative bioanalysis. Bioanalysis. PMID 29171758 DOI: 10.4155/Bio-2017-0179  0.678
2016 Kellie JF, Kehler JR, Mencken TJ, Snell RJ, Hottenstein CS. A whole-molecule immunocapture LC-MS approach for the in vivo quantitation of biotherapeutics. Bioanalysis. PMID 27611496 DOI: 10.4155/Bio-2016-0180  0.481
2016 Kellie JF, Kehler JR, Szapacs ME. Application of high-resolution MS for development of peptide and large-molecule drug candidates. Bioanalysis. PMID 26795399 DOI: 10.4155/Bio.15.249  0.552
2015 Lee H, Le HV, Wu R, Doud E, Sanishvili R, Kellie JF, Compton PD, Pachaiyappan B, Liu D, Kelleher NL, Silverman RB. Mechanism of Inactivation of GABA Aminotransferase by (E)- and (Z)-(1S,3S)-3-Amino-4-fluoromethylenyl-1-cyclopentanoic Acid. Acs Chemical Biology. PMID 26110556 DOI: 10.1021/Acschembio.5B00212  0.41
2014 Kellie J, Szapacs M. Quantitative immunocapture MS: Current status and challenges in drug discovery Bioanalysis. 6: 2335-2337. PMID 25384587 DOI: 10.4155/Bio.14.178  0.625
2014 Kellie JF, Higgs RE, Ryder JW, Major A, Beach TG, Adler CH, Merchant K, Knierman MD. Quantitative measurement of intact alpha-synuclein proteoforms from post-mortem control and Parkinson's disease brain tissue by intact protein mass spectrometry. Scientific Reports. 4: 5797. PMID 25052239 DOI: 10.1038/Srep05797  0.385
2012 Tipton JD, Tran JC, Catherman AD, Ahlf DR, Durbin KR, Lee JE, Kellie JF, Kelleher NL, Hendrickson CL, Marshall AG. Nano-LC FTICR tandem mass spectrometry for top-down proteomics: routine baseline unit mass resolution of whole cell lysate proteins up to 72 kDa. Analytical Chemistry. 84: 2111-7. PMID 22356091 DOI: 10.1021/Ac202651V  0.877
2012 Kellie JF, Catherman AD, Durbin KR, Tran JC, Tipton JD, Norris JL, Witkowski CE, Thomas PM, Kelleher NL. Robust analysis of the yeast proteome under 50 kDa by molecular-mass-based fractionation and top-down mass spectrometry. Analytical Chemistry. 84: 209-15. PMID 22103811 DOI: 10.1021/Ac202384V  0.867
2011 Tran JC, Zamdborg L, Ahlf DR, Lee JE, Catherman AD, Durbin KR, Tipton JD, Vellaichamy A, Kellie JF, Li M, Wu C, Sweet SM, Early BP, Siuti N, LeDuc RD, et al. Mapping intact protein isoforms in discovery mode using top-down proteomics. Nature. 480: 254-8. PMID 22037311 DOI: 10.1038/Nature10575  0.688
2010 Durbin KR, Tran JC, Zamdborg L, Sweet SM, Catherman AD, Lee JE, Li M, Kellie JF, Kelleher NL. Intact mass detection, interpretation, and visualization to automate Top-Down proteomics on a large scale. Proteomics. 10: 3589-97. PMID 20848673 DOI: 10.1002/Pmic.201000177  0.816
2010 Robinson RA, Kellie JF, Kaufman TC, Clemmer DE. Insights into aging through measurements of the Drosophila proteome as a function of temperature. Mechanisms of Ageing and Development. 131: 584-90. PMID 20732347 DOI: 10.1016/J.Mad.2010.08.004  0.542
2010 Kellie JF, Tran JC, Lee JE, Ahlf DR, Thomas HM, Ntai I, Catherman AD, Durbin KR, Zamdborg L, Vellaichamy A, Thomas PM, Kelleher NL. The emerging process of Top Down mass spectrometry for protein analysis: biomarkers, protein-therapeutics, and achieving high throughput. Molecular Biosystems. 6: 1532-9. PMID 20711533 DOI: 10.1039/C000896F  0.779
2010 Vellaichamy A, Tran JC, Catherman AD, Lee JE, Kellie JF, Sweet SM, Zamdborg L, Thomas PM, Ahlf DR, Durbin KR, Valaskovic GA, Kelleher NL. Size-sorting combined with improved nanocapillary liquid chromatography-mass spectrometry for identification of intact proteins up to 80 kDa. Analytical Chemistry. 82: 1234-44. PMID 20073486 DOI: 10.1021/Ac9021083  0.807
2009 Lee JE, Kellie JF, Tran JC, Tipton JD, Catherman AD, Thomas HM, Ahlf DR, Durbin KR, Vellaichamy A, Ntai I, Marshall AG, Kelleher NL. A robust two-dimensional separation for top-down tandem mass spectrometry of the low-mass proteome. Journal of the American Society For Mass Spectrometry. 20: 2183-91. PMID 19747844 DOI: 10.1016/J.Jasms.2009.08.001  0.776
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