Year |
Citation |
Score |
2015 |
Li T, He X, Thomas JM, Yang D, Zhong S, Xue F, Smith WW. A novel GTP-binding inhibitor, FX2149, attenuates LRRK2 toxicity in Parkinson's disease models. Plos One. 10: e0122461. PMID 25816252 DOI: 10.1371/Journal.Pone.0122461 |
0.317 |
|
2014 |
Li T, Yang D, Zhong S, Thomas JM, Xue F, Liu J, Kong L, Voulalas P, Hassan HE, Park JS, MacKerell AD, Smith WW. Novel LRRK2 GTP-binding inhibitors reduced degeneration in Parkinson's disease cell and mouse models. Human Molecular Genetics. 23: 6212-22. PMID 24993787 DOI: 10.1093/Hmg/Ddu341 |
0.303 |
|
2010 |
Cerchietti LC, Ghetu AF, Zhu X, Da Silva GF, Zhong S, Matthews M, Bunting KL, Polo JM, Farès C, Arrowsmith CH, Yang SN, Garcia M, Coop A, Mackerell AD, Privé GG, et al. A small-molecule inhibitor of BCL6 kills DLBCL cells in vitro and in vivo. Cancer Cell. 17: 400-11. PMID 20385364 DOI: 10.1016/J.Ccr.2009.12.050 |
0.326 |
|
2009 |
Sorci L, Pan Y, Eyobo Y, Rodionova I, Huang N, Kurnasov O, Zhong S, MacKerell AD, Zhang H, Osterman AL. Targeting NAD Biosynthesis in Bacterial Pathogens: Structure-Based Development of Inhibitors of Nicotinate Mononucleotide Adenylyltransferase NadD Chemistry and Biology. 16: 849-861. PMID 19716475 DOI: 10.1016/J.Chembiol.2009.07.006 |
0.302 |
|
2009 |
Charpentier TH, Wilder PT, Liriano MA, Varney KM, Zhong S, Coop A, Pozharski E, MacKerell AD, Toth EA, Weber DJ. Small molecules bound to unique sites in the target protein binding cleft of calcium-bound S100B as characterized by nuclear magnetic resonance and X-ray crystallography. Biochemistry. 48: 6202-12. PMID 19469484 DOI: 10.1021/Bi9005754 |
0.33 |
|
2009 |
Cerchietti LC, Ghetu A, Zhu X, Silva GD, Zhong S, Matthews M, Polo J, Farès C, Arrowsmith C, Bunting K, Coop A, MacKerell A, Privè G, Melnick A. Abstract B236: A small molecule disrupts the BCL6 transcriptional repressor complex and kills lymphoma cells in vitro and in vivo Molecular Cancer Therapeutics. 8. DOI: 10.1158/1535-7163.Targ-09-B236 |
0.344 |
|
2008 |
Zhong S, MacKerell AD. Pose scaling: Geometrical assessment of ligand binding poses Journal of Theoretical and Computational Chemistry. 7: 833-852. DOI: 10.1142/S0219633608004155 |
0.3 |
|
2007 |
Zhong S, Mackerell AD. Binding response: A descriptor for selecting ligand binding site on protein surfaces Journal of Chemical Information and Modeling. 47: 2303-2315. PMID 17900106 DOI: 10.1021/Ci700149K |
0.314 |
|
2007 |
Furci LM, Lopes P, Eakanunkul S, Zhong S, MacKerell AD, Wilks A. Inhibition of the bacterial heme oxygenases from Pseudomonas aeruginosa and Neisseria meningitidis: novel antimicrobial targets. Journal of Medicinal Chemistry. 50: 3804-13. PMID 17629261 DOI: 10.1021/Jm0700969 |
0.306 |
|
2006 |
Chen F, Hancock CN, Macias AT, Joh J, Still K, Zhong S, MacKerell AD, Shapiro P. Characterization of ATP-independent ERK inhibitors identified through in silico analysis of the active ERK2 structure. Bioorganic & Medicinal Chemistry Letters. 16: 6281-7. PMID 17000106 DOI: 10.1016/J.Bmcl.2006.09.038 |
0.316 |
|
2002 |
Zhong S, Dadarlat VM, Glaeser RM, Head-Gordon T, Downing KH. Modeling chemical bonding effects for protein electron crystallography: the transferable fragmental electrostatic potential (TFESP) method. Acta Crystallographica. Section a, Foundations of Crystallography. 58: 162-70. PMID 11832586 DOI: 10.1107/S0108767301020256 |
0.459 |
|
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