Ramasamy Paulmurugan - Publications

Affiliations: 
Radiology Stanford University, Palo Alto, CA 

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Year Citation  Score
2020 Bose RJ, Tharmalingam N, Garcia Marques FJ, Sukumar UK, Natarajan A, Zeng Y, Robinson E, Bermudez A, Chang E, Habte F, Pitteri SJ, McCarthy J, Gambhir SS, Massoud TF, Mylonakis E, ... Paulmurugan R, et al. Reconstructed Apoptotic Bodies as Targeted 'Nano Decoys' to Treat Intracellular Bacterial Infections within Macrophages and Cancer Cells. Acs Nano. PMID 32347709 DOI: 10.1021/acsnano.0c00921  0.84
2020 Kim SB, Hori SS, Sadeghipour N, Sukumar UK, Fujii R, Massoud TF, Paulmurugan R. Highly sensitive eight-channel light sensing system for biomedical applications. Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society For Photobiology. PMID 32159572 DOI: 10.1039/d0pp00017e  0.84
2020 Peterson KM, Franchi F, Olthoff M, Chen IY, Paulmurugan R, Rodriguez-Porcel M. Pathway-specific reporter genes to study stem cell biology. Stem Cells (Dayton, Ohio). PMID 32129537 DOI: 10.1002/stem.3167  0.8
2020 Sukumar UK, Rajendran JCB, Gambhir SS, Massoud TF, Paulmurugan R. SP94-Targeted Triblock Co-Polymer Nanoparticle Delivers Thymidine Kinase-p53-Nitroreductase Triple Therapeutic Gene and Restores Anticancer Function against Hepatocellular Carcinoma in vivo. Acs Applied Materials & Interfaces. PMID 32048820 DOI: 10.1021/acsami.9b20071  0.84
2020 Zheng F, Li P, Bachawal SV, Wang H, Li C, Yuan W, Huang B, Paulmurugan R. Assessment of Metastatic and Reactive Sentinel Lymph Nodes with B7-H3-Targeted Ultrasound Molecular Imaging: A Longitudinal Study in Mouse Models. Molecular Imaging and Biology. PMID 32034623 DOI: 10.1007/s11307-020-01478-9  0.56
2020 Wischhusen JC, Chowdhury SM, Lee T, Wang H, Bachawal S, Devulapally R, Afjei R, Sukumar UK, Paulmurugan R. Ultrasound-mediated delivery of miRNA-122 and anti-miRNA-21 therapeutically immunomodulates murine hepatocellular carcinoma in vivo. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 32004588 DOI: 10.1016/j.jconrel.2020.01.051  0.84
2020 Bam R, Lown PS, Stern LA, Sharma K, Wilson KE, Bean GR, Lutz AM, Paulmurugan R, Hackel BJ, Dahl J, Abou-Elkacem L. Efficacy of affibody-based ultrasound molecular imaging of vascular B7-H3 for breast cancer detection. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 31924738 DOI: 10.1158/1078-0432.CCR-19-1655  0.52
2020 Franchi F, Ramaswamy V, Olthoff M, Peterson KM, Paulmurugan R, Rodriguez-Porcel M. The Myocardial Microenvironment Modulates the Biology of Transplanted Mesenchymal Stem Cells. Molecular Imaging and Biology. PMID 31907845 DOI: 10.1007/s11307-019-01470-y  0.8
2019 Bae Kim S, Fujii R, Natarajan A, Massoud TF, Paulmurugan R. Ligand-activated BRET9 imaging for measuring protein-protein interactions in living mice. Chemical Communications (Cambridge, England). PMID 31807738 DOI: 10.1039/c9cc07634d  0.84
2019 Kimura RH, Wang L, Shen B, Huo L, Tummers W, Filipp FV, Guo HH, Haywood T, Abou-Elkacem L, Baratto L, Habte F, Devulapally R, Witney TH, Cheng Y, Tikole S, ... ... Paulmurugan R, et al. Evaluation of integrin αvβ cystine knot PET tracers to detect cancer and idiopathic pulmonary fibrosis. Nature Communications. 10: 4673. PMID 31611594 DOI: 10.1038/s41467-019-11863-w  0.84
2019 Kanada M, Kim BD, Hardy JW, Bachmann MH, Bernard MP, Perez GI, Zarea AA, Ge TJ, Withrow A, Ibrahim SA, Toomajian V, Gambhir SS, Paulmurugan R, Contag CH, Ronald JA. Microvesicle-mediated delivery of minicircle DNA results in effective gene-directed enzyme prodrug cancer therapy. Molecular Cancer Therapeutics. PMID 31451563 DOI: 10.1158/1535-7163.MCT-19-0299  0.84
2019 Sukumar UK, Bose RJC, Malhotra M, Babikir HA, Afjei R, Robinson E, Zeng Y, Chang E, Habte F, Sinclair R, Gambhir SS, Massoud TF, Paulmurugan R. Intranasal delivery of targeted polyfunctional gold-iron oxide nanoparticles loaded with therapeutic microRNAs for combined theranostic multimodality imaging and presensitization of glioblastoma to temozolomide. Biomaterials. 218: 119342. PMID 31326657 DOI: 10.1016/j.biomaterials.2019.119342  0.84
2019 Di Ianni T, Bose RJC, Sukumar UK, Bachawal S, Wang H, Telichko A, Herickhoff C, Robinson E, Baker S, Vilches-Moure JG, Felt SA, Gambhir SS, Paulmurugan R, Dahl JD. Ultrasound/microbubble-mediated targeted delivery of anticancer microRNA-loaded nanoparticles to deep tissues in pigs. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 31326463 DOI: 10.1016/j.jconrel.2019.07.024  0.84
2019 Nishihara R, Paulmurugan R, Nakajima T, Yamamoto E, Natarajan A, Afjei R, Hiruta Y, Iwasawa N, Nishiyama S, Citterio D, Sato M, Kim SB, Suzuki K. Highly bright and stable NIR-BRET with blue-shifted coelenterazine derivatives for deep-tissue imaging of molecular events . Theranostics. 9: 2646-2661. PMID 31131059 DOI: 10.7150/thno.32219  0.84
2019 Paulmurugan R, Malhotra M, Massoud TF. The protean world of non-coding RNAs in glioblastoma. Journal of Molecular Medicine (Berlin, Germany). PMID 31129756 DOI: 10.1007/s00109-019-01798-6  0.84
2019 Kim SB, Fujii R, Nishihara R, Bose RJC, Citterio D, Suzuki K, Massoud TF, Paulmurugan R. Molecular imaging of retinoic acids in live cells using single-chain bioluminescence probes. Acs Combinatorial Science. PMID 31034200 DOI: 10.1021/acscombsci.9b00035  0.84
2019 Abe M, Nishihara R, Ikeda Y, Nakajima T, Sato M, Iwasawa N, Nishiyama S, Paulmurugan R, Citterio D, Kim SB, Suzuki K. Near Infrared bioluminescence imaging with Through-Bond Energy Transfer Cassette. Chembiochem : a European Journal of Chemical Biology. PMID 30957352 DOI: 10.1002/cbic.201900149  0.6
2019 Kim SB, Nishihara R, Fujii R, Paulmurugan R, Citterio D, Suzuki K. In vitro Determination of Rapamycin-triggered FKBP-FRB Interactions Using a Molecular Tension Probe. Analytical Sciences : the International Journal of the Japan Society For Analytical Chemistry. 35: 71-78. PMID 30504653 DOI: 10.2116/analsci.18SDP08  0.6
2018 Kumar N, Afjei R, Massoud TF, Paulmurugan R. Comparison of cell-based assays to quantify treatment effects of anticancer drugs identifies a new application for Bodipy-L-cystine to measure apoptosis. Scientific Reports. 8: 16363. PMID 30397244 DOI: 10.1038/s41598-018-34696-x  0.84
2018 Jc Bose R, Uday Kumar S, Zeng Y, Afjei R, Robinson E, Lau K, Bermudez A, Habte F, Pitteri SJ, Sinclair R, Willmann JK, Massoud TF, Gambhir SS, Paulmurugan R. Tumor Cell-Derived Extracellular Vesicle-Coated Nanocarriers: An Efficient Theranostic Platform for the Cancer-Specific Delivery of Anti-miR-21 and Imaging Agents. Acs Nano. PMID 30346694 DOI: 10.1021/acsnano.8b02587  0.84
2018 Babikir HA, Afjei R, Paulmurugan R, Massoud TF. Restoring guardianship of the genome: Anticancer drug strategies to reverse oncogenic mutant p53 misfolding. Cancer Treatment Reviews. 71: 19-31. PMID 30336366 DOI: 10.1016/j.ctrv.2018.09.004  0.84
2018 Li K, Chan CT, Nejadnik H, Lenkov OD, Wolterman C, Paulmurugan R, Yang H, Gambhir SS, Daldrup-Link HE. Ferumoxytol-based Dual-modality Imaging Probe for Detection of Stem Cell Transplant Rejection. Nanotheranostics. 2: 306-319. PMID 29977742 DOI: 10.7150/ntno.26389  0.84
2018 Devulapally R, Lee T, Barghava-Shah A, Sekar TV, Foygel K, Bachawal SV, Willmann JK, Paulmurugan R. Ultrasound-guided delivery of thymidine kinase-nitroreductase dual therapeutic genes by PEGylated-PLGA/PIE nanoparticles for enhanced triple negative breast cancer therapy. Nanomedicine (London, England). PMID 29790803 DOI: 10.2217/nnm-2017-0328  0.84
2018 Paulmurugan R, Afjei R, Sekar TV, Babikir HA, Massoud TF. A protein folding molecular imaging biosensor monitors the effects of drugs that restore mutant p53 structure and its downstream function in glioblastoma cells. Oncotarget. 9: 21495-21511. PMID 29765555 DOI: 10.18632/oncotarget.25138  0.84
2018 Malhotra M, Sekar TV, Ananta JS, Devulapally R, Afjei R, Babikir HA, Paulmurugan R, Massoud TF. Targeted nanoparticle delivery of therapeutic antisense microRNAs presensitizes glioblastoma cells to lower effective doses of temozolomide and in a mouse model. Oncotarget. 9: 21478-21494. PMID 29765554 DOI: 10.18632/oncotarget.25135  0.84
2018 Chowdhury SM, Lee T, Bachawal SV, Devulapally R, Abou-Elkacem L, Yeung TA, Wischhusen J, Tian L, Dahl J, Paulmurugan R, Willmann JK. Longitudinal assessment of ultrasound-guided complementary microRNA therapy of hepatocellular carcinoma. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 29758233 DOI: 10.1016/j.jconrel.2018.05.009  0.8
2017 Gaur S, Bhargava-Shah A, Hori S, Afjei R, Sekar TV, Gambhir SS, Massoud TF, Paulmurugan R. Engineering intracellularly retained Gaussia Luciferase reporters for improved biosensing and molecular imaging applications. Acs Chemical Biology. PMID 28767220 DOI: 10.1021/acschembio.7b00454  0.84
2017 Hori SS, Lutz AM, Paulmurugan R, Gambhir SS. A model-based personalized cancer screening strategy for detecting early-stage tumors using blood-borne biomarkers. Cancer Research. PMID 28283654 DOI: 10.1158/0008-5472.CAN-16-2904  0.84
2016 Devulapally R, Foygel K, Sekar TV, Willmann JK, Paulmurugan R. Gemcitabine and Antisense-microRNA Co-encapsulated PLGA-PEG Polymer Nanoparticles for Hepatocellular Carcinoma Therapy. Acs Applied Materials & Interfaces. 8: 33412-33422. PMID 27960411 DOI: 10.1021/acsami.6b08153  0.84
2016 Oronsky B, Paulmurugan R, Foygel K, Scicinski J, Knox SJ, Peehl D, Zhao H, Ning S, Cabrales P, Summers TA, Reid TR, Fitch WL, Kim MM, Trepel JB, Lee MJ, et al. RRx-001: A Systemically Non-Toxic M2-to-M1 Macrophage Stimulating and Prosensitizing Agent In Phase II Clinical Trials. Expert Opinion On Investigational Drugs. PMID 27935336 DOI: 10.1080/13543784.2017.1268600  0.68
2016 Sekar TV, Foygel K, Devulapally R, Kumar V, Malhotra S, Massoud TF, Paulmurugan R. Molecular Imaging Biosensor Monitors p53 Sumoylation in Cells and Living Mice. Analytical Chemistry. 88: 11420-11428. PMID 27934110 DOI: 10.1021/acs.analchem.6b02048  0.84
2016 Calibasi Kocal G, Güven S, Foygel K, Goldman A, Chen P, Sengupta S, Paulmurugan R, Baskin Y, Demirci U. Dynamic Microenvironment Induces Phenotypic Plasticity of Esophageal Cancer Cells Under Flow. Scientific Reports. 6: 38221. PMID 27910892 DOI: 10.1038/srep38221  0.68
2016 Sekar TV, Foygel K, Massoud TF, Gambhir SS, Paulmurugan R. A transgenic mouse model expressing an ERα folding biosensor reveals the effects of Bisphenol A on estrogen receptor signaling. Scientific Reports. 6: 34788. PMID 27721470 DOI: 10.1038/srep34788  0.84
2016 Ananta JS, Paulmurugan R, Massoud TF. Tailored Nanoparticle Codelivery of antimiR-21 and antimiR-10b Augments Glioblastoma Cell Kill by Temozolomide: Toward a "Personalized" Anti-microRNA Therapy. Molecular Pharmaceutics. 13: 3164-75. PMID 27508339 DOI: 10.1021/acs.molpharmaceut.6b00388  0.84
2016 Chowdhury SM, Wang TY, Bachawal S, Devulapally R, Choe JW, Elkacem LA, Yakub BK, Wang DS, Tian L, Paulmurugan R, Willmann JK. Ultrasound-Guided Therapeutic Modulation of Hepatocellular Carcinoma using Complementary microRNAs. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 27503707 DOI: 10.1016/j.jconrel.2016.08.005  0.8
2016 Sekar TV, Paulmurugan R. Theranostic Imaging of Cancer Gene Therapy. Methods in Molecular Biology (Clifton, N.J.). 1461: 241-54. PMID 27424910 DOI: 10.1007/978-1-4939-3813-1_20  0.84
2016 Sekar TV, Paulmurugan R. Imaging Histone Methylations in Living Animals. Methods in Molecular Biology (Clifton, N.J.). 1461: 203-15. PMID 27424907 DOI: 10.1007/978-1-4939-3813-1_17  0.84
2016 Parashurama N, Ahn BC, Ziv K, Ito K, Paulmurugan R, Willmann JK, Chung J, Ikeno F, Swanson JC, Merk DR, Lyons JK, Yerushalmi D, Teramoto T, Kosuge H, Dao CN, et al. Multimodality Molecular Imaging of Cardiac Cell Transplantation: Part II. In Vivo Imaging of Bone Marrow Stromal Cells in Swine with PET/CT and MR Imaging. Radiology. 151150. PMID 27332865 DOI: 10.1148/radiol.2016151150  0.8
2016 Parashurama N, Ahn BC, Ziv K, Ito K, Paulmurugan R, Willmann JK, Chung J, Ikeno F, Swanson JC, Merk DR, Lyons JK, Yerushalmi D, Teramoto T, Kosuge H, Dao CN, et al. Multimodality Molecular Imaging of Cardiac Cell Transplantation: Part I. Reporter Gene Design, Characterization, and Optical in Vivo Imaging of Bone Marrow Stromal Cells after Myocardial Infarction. Radiology. 140049. PMID 27308957 DOI: 10.1148/radiol.2016140049  0.8
2016 Sheahan AV, Sekar TV, Chen K, Paulmurugan R, Massoud TF. A molecular imaging biosensor detects in vivo protein folding and misfolding. Journal of Molecular Medicine (Berlin, Germany). PMID 27277823 DOI: 10.1007/s00109-016-1437-9  0.84
2016 Liu Y, Zhang Y, Jiang J, Lobie PE, Paulmurugan R, Langenheim JF, Chen WY, Zinn KR, Frank SJ. GHR/PRLR Hetero-multimer is Composed of GHR Homodimers and PRLR Homodimers. Molecular Endocrinology (Baltimore, Md.). me20151319. PMID 27003442 DOI: 10.1210/me.2015-1319  0.8
2016 Ananta JS, Paulmurugan R, Massoud TF. Temozolomide-loaded PLGA nanoparticles to treat glioblastoma cells: a biophysical and cell culture evaluation. Neurological Research. 38: 51-9. PMID 26905383 DOI: 10.1080/01616412.2015.1133025  0.84
2016 Franchi F, Peterson KM, Paulmurugan R, Folmes C, Lanza IR, Lerman A, Rodriguez-Porcel M. Noninvasive Monitoring of the Mitochondrial Function in Mesenchymal Stromal Cells. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. PMID 26865378 DOI: 10.1007/s11307-016-0929-x  0.8
2016 Bhargava-Shah A, Foygel K, Devulapally R, Paulmurugan R. Orlistat and antisense-miRNA-loaded PLGA-PEG nanoparticles for enhanced triple negative breast cancer therapy. Nanomedicine (London, England). 11: 235-47. PMID 26787319 DOI: 10.2217/nnm.15.193  0.68
2015 Ananta JS, Paulmurugan R, Massoud TF. Nanoparticle-Delivered Antisense MicroRNA-21 Enhances the Effects of Temozolomide on Glioblastoma Cells. Molecular Pharmaceutics. 12: 4509-17. PMID 26559642 DOI: 10.1021/acs.molpharmaceut.5b00694  0.84
2015 Paulmurugan R, Bhethanabotla R, Mishra K, Devulapally R, Foygel K, Sekar TV, Ananta JS, Massoud TF, Joy A. Folate Receptor Targeted Polymeric Micellar Nanocarriers for Delivery of Orlistat as a Repurposed Drug against Triple Negative Breast Cancer. Molecular Cancer Therapeutics. PMID 26553061 DOI: 10.1158/1535-7163.MCT-15-0579  0.84
2015 Foygel K, Sekar TV, Paulmurugan R. Monitoring the Antioxidant Mediated Chemosensitization and ARE-Signaling in Triple Negative Breast Cancer Therapy. Plos One. 10: e0141913. PMID 26536456 DOI: 10.1371/journal.pone.0141913  0.84
2015 Ning S, Sekar TV, Scicinski J, Oronsky B, Peehl DM, Knox SJ, Paulmurugan R. Nrf2 activity as a potential biomarker for the pan-epigenetic anticancer agent, RRx-001. Oncotarget. 6: 21547-56. PMID 26280276 DOI: 10.18632/oncotarget.4249  0.84
2015 Hwang GL, van den Bosch MA, Kim YI, Katzenberg R, Willmann JK, Paulmurugan R, Gambhir SS, Hofmann L. Development of a High-Throughput Molecular Imaging-Based Orthotopic Hepatocellular Carcinoma Model. CurēUs. 7: e281. PMID 26180705 DOI: 10.7759/cureus.281  0.84
2015 Devulapally R, Sekar TV, Paulmurugan R. Formulation of Anti-miR-21 and 4-Hydroxytamoxifen Co-loaded Biodegradable Polymer Nanoparticles and Their Antiproliferative Effect on Breast Cancer Cells. Molecular Pharmaceutics. 12: 2080-92. PMID 25880495 DOI: 10.1021/mp500852s  0.84
2015 Wang TY, Choe JW, Pu K, Devulapally R, Bachawal S, Machtaler S, Chowdhury SM, Luong R, Tian L, Khuri-Yakub B, Rao J, Paulmurugan R, Willmann JK. Ultrasound-guided delivery of microRNA loaded nanoparticles into cancer. Journal of Controlled Release : Official Journal of the Controlled Release Society. 203: 99-108. PMID 25687306 DOI: 10.1016/j.jconrel.2015.02.018  0.8
2015 Devulapally R, Sekar NM, Sekar TV, Foygel K, Massoud TF, Willmann JK, Paulmurugan R. Polymer nanoparticles mediated codelivery of antimiR-10b and antimiR-21 for achieving triple negative breast cancer therapy. Acs Nano. 9: 2290-302. PMID 25652012 DOI: 10.1021/nn507465d  0.8
2015 Sekar TV, Foygel K, Gelovani JG, Paulmurugan R. Genetically encoded molecular biosensors to image histone methylation in living animals. Analytical Chemistry. 87: 892-9. PMID 25506787 DOI: 10.1021/ac502629r  0.84
2015 Sekar TV, Foygel K, Devulapally R, Paulmurugan R. Degron protease blockade sensor to image epigenetic histone protein methylation in cells and living animals. Acs Chemical Biology. 10: 165-74. PMID 25489787 DOI: 10.1021/cb5008037  0.84
2014 Liu Y, Berry PA, Zhang Y, Jiang J, Lobie PE, Paulmurugan R, Langenheim JF, Chen WY, Zinn KR, Frank SJ. Dynamic analysis of GH receptor conformational changes by split luciferase complementation. Molecular Endocrinology (Baltimore, Md.). 28: 1807-19. PMID 25188449 DOI: 10.1210/me.2014-1153  0.8
2014 Ahn BC, Parashurama N, Patel M, Ziv K, Bhaumik S, Yaghoubi SS, Paulmurugan R, Gambhir SS. Noninvasive reporter gene imaging of human Oct4 (pluripotency) dynamics during the differentiation of embryonic stem cells in living subjects. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. 16: 865-76. PMID 24845530 DOI: 10.1007/s11307-014-0744-1  0.8
2014 Sekar TV, Foygel K, Ilovich O, Paulmurugan R. Noninvasive theranostic imaging of HSV1-sr39TK-NTR/GCV-CB1954 dual-prodrug therapy in metastatic lung lesions of MDA-MB-231 triple negative breast cancer in mice. Theranostics. 4: 460-74. PMID 24669276 DOI: 10.7150/thno.8077  0.84
2014 Bhakkiyalakshmi E, Shalini D, Sekar TV, Rajaguru P, Paulmurugan R, Ramkumar KM. Therapeutic potential of pterostilbene against pancreatic beta-cell apoptosis mediated through Nrf2. British Journal of Pharmacology. 171: 1747-57. PMID 24417315 DOI: 10.1111/bph.12577  0.84
2014 Devulapally R, Paulmurugan R. Polymer nanoparticles for drug and small silencing RNA delivery to treat cancers of different phenotypes. Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology. 6: 40-60. PMID 23996830 DOI: 10.1002/wnan.1242  0.6
2014 Chen IY, Paulmurugan R, Nielsen CH, Wang DS, Chow V, Robbins RC, Gambhir SS. A titratable two-step transcriptional amplification strategy for targeted gene therapy based on ligand-induced intramolecular folding of a mutant human estrogen receptor. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. 16: 224-34. PMID 23955099 DOI: 10.1007/s11307-013-0673-4  0.8
2013 Sekar TV, Paulmurugan R. H-Penciclovir (H-PCV) Uptake Assay. Bio-Protocol. 3. PMID 27446976  0.84
2013 Sekar TV, Mohanram RK, Foygel K, Paulmurugan R. Therapeutic evaluation of microRNAs by molecular imaging. Theranostics. 3: 964-85. PMID 24396507 DOI: 10.7150/thno.4928  0.84
2013 Yan X, Ray P, Paulmurugan R, Tong R, Gong Y, Sathirachinda A, Wu JC, Gambhir SS. A transgenic tri-modality reporter mouse. Plos One. 8: e73580. PMID 23951359 DOI: 10.1371/journal.pone.0073580  0.8
2013 Chen IY, Gheysens O, Li Z, Rasooly JA, Wang Q, Paulmurugan R, Rosenberg J, Rodriguez-Porcel M, Willmann JK, Wang DS, Contag CH, Robbins RC, Wu JC, Gambhir SS. Noninvasive imaging of hypoxia-inducible factor-1α gene therapy for myocardial ischemia. Human Gene Therapy Methods. 24: 279-88. PMID 23937265 DOI: 10.1089/hgtb.2013.028  0.8
2013 Ramkumar KM, Sekar TV, Foygel K, Elango B, Paulmurugan R. Reporter protein complementation imaging assay to screen and study Nrf2 activators in cells and living animals. Analytical Chemistry. 85: 7542-9. PMID 23826874 DOI: 10.1021/ac401569j  0.84
2013 Fan-Minogue H, Bodapati S, Solow-Cordero D, Fan A, Paulmurugan R, Massoud TF, Felsher DW, Gambhir SS. A c-Myc activation sensor-based high-throughput drug screening identifies an antineoplastic effect of nitazoxanide. Molecular Cancer Therapeutics. 12: 1896-905. PMID 23825064 DOI: 10.1158/1535-7163.MCT-12-1243  0.8
2012 Panje CM, Wang DS, Pysz MA, Paulmurugan R, Ren Y, Tranquart F, Tian L, Willmann JK. Ultrasound-mediated gene delivery with cationic versus neutral microbubbles: effect of DNA and microbubble dose on in vivo transfection efficiency. Theranostics. 2: 1078-91. PMID 23227124 DOI: 10.7150/thno.4240  0.8
2012 Chan CT, Reeves RE, Geller R, Yaghoubi SS, Hoehne A, Solow-Cordero DE, Chiosis G, Massoud TF, Paulmurugan R, Gambhir SS. Discovery and validation of small-molecule heat-shock protein 90 inhibitors through multimodality molecular imaging in living subjects. Proceedings of the National Academy of Sciences of the United States of America. 109: E2476-85. PMID 22895790 DOI: 10.1073/pnas.1205459109  0.8
2012 Wang DS, Panje C, Pysz MA, Paulmurugan R, Rosenberg J, Gambhir SS, Schneider M, Willmann JK. Cationic versus neutral microbubbles for ultrasound-mediated gene delivery in cancer. Radiology. 264: 721-32. PMID 22723497 DOI: 10.1148/radiol.12112368  0.84
2012 Ramkumar KM, Manjula C, Gnanakumar G, Kanjwal MA, Sekar TV, Paulmurugan R, Rajaguru P. Oxidative stress-mediated cytotoxicity and apoptosis induction by TiO2 nanofibers in HeLa cells. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V. 81: 324-33. PMID 22446064 DOI: 10.1016/j.ejpb.2012.02.013  0.84
2012 Kim YI, Ahn BC, Ronald JA, Katzenberg R, Singh A, Paulmurugan R, Ray S, Gambhir SS, Hofmann LV. Intratumoral versus intravenous gene therapy using a transcriptionally targeted viral vector in an orthotopic hepatocellular carcinoma rat model. Journal of Vascular and Interventional Radiology : Jvir. 23: 704-11. PMID 22387029 DOI: 10.1016/j.jvir.2012.01.053  0.84
2011 Paulmurugan R, Tamrazi A, Massoud TF, Katzenellenbogen JA, Gambhir SS. In vitro and in vivo molecular imaging of estrogen receptor α and β homo- and heterodimerization: exploration of new modes of receptor regulation. Molecular Endocrinology (Baltimore, Md.). 25: 2029-40. PMID 22052998 DOI: 10.1210/me.2011-1145  0.8
2011 Thakor AS, Luong R, Paulmurugan R, Lin FI, Kempen P, Zavaleta C, Chu P, Massoud TF, Sinclair R, Gambhir SS. The fate and toxicity of Raman-active silica-gold nanoparticles in mice. Science Translational Medicine. 3: 79ra33. PMID 21508310 DOI: 10.1126/scitranslmed.3001963  0.8
2011 Sekar TV, Dhanabalan A, Paulmurugan R. Imaging cellular receptors in breast cancers: An overview Current Pharmaceutical Biotechnology. 12: 508-527. PMID 21342102 DOI: 10.2174/138920111795164039  0.8
2011 Gheysens O, Chen IY, Rodriguez-Porcel M, Chan C, Rasooly J, Vaerenberg C, Paulmurugan R, Willmann JK, Deroose C, Wu J, Gambhir SS. Non-invasive bioluminescence imaging of myoblast-mediated hypoxia-inducible factor-1 alpha gene transfer. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. 13: 1124-32. PMID 21267661 DOI: 10.1007/s11307-011-0471-9  0.8
2011 Thakor AS, Paulmurugan R, Kempen P, Zavaleta C, Sinclair R, Massoud TF, Gambhir SS. Oxidative stress mediates the effects of Raman-active gold nanoparticles in human cells. Small (Weinheim An Der Bergstrasse, Germany). 7: 126-36. PMID 21104804 DOI: 10.1002/smll.201001466  0.8
2010 Fan-Minogue H, Cao Z, Paulmurugan R, Chan CT, Massoud TF, Felsher DW, Gambhir SS. Noninvasive molecular imaging of c-Myc activation in living mice. Proceedings of the National Academy of Sciences of the United States of America. 107: 15892-7. PMID 20713710 DOI: 10.1073/pnas.1007443107  0.8
2010 Massoud TF, Paulmurugan R, Gambhir SS. A molecularly engineered split reporter for imaging protein-protein interactions with positron emission tomography. Nature Medicine. 16: 921-6. PMID 20639890 DOI: 10.1038/nm.2185  0.84
2010 Rodriguez-Porcel M, Gheysens O, Paulmurugan R, Chen IY, Peterson KM, Willmann JK, Wu JC, Zhu X, Lerman LO, Gambhir SS. Antioxidants improve early survival of cardiomyoblasts after transplantation to the myocardium. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. 12: 325-34. PMID 20013064 DOI: 10.1007/s11307-009-0274-4  0.8
2009 Paulmurugan R, Padmanabhan P, Ahn BC, Ray S, Willmann JK, Massoud TF, Biswal S, Gambhir SS. A novel estrogen receptor intramolecular folding-based titratable transgene expression system. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 1703-11. PMID 19654568 DOI: 10.1038/mt.2009.171  0.8
2009 Willmann JK, Paulmurugan R, Rodriguez-Porcel M, Stein W, Brinton TJ, Connolly AJ, Nielsen CH, Lutz AM, Lyons J, Ikeno F, Suzuki Y, Rosenberg J, Chen IY, Wu JC, Yeung AC, et al. Imaging gene expression in human mesenchymal stem cells: from small to large animals. Radiology. 252: 117-27. PMID 19366903 DOI: 10.1148/radiol.2513081616  0.8
2009 Chen IY, Greve JM, Gheysens O, Willmann JK, Rodriguez-Porcel M, Chu P, Sheikh AY, Faranesh AZ, Paulmurugan R, Yang PC, Wu JC, Gambhir SS. Comparison of optical bioluminescence reporter gene and superparamagnetic iron oxide MR contrast agent as cell markers for noninvasive imaging of cardiac cell transplantation. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. 11: 178-87. PMID 19034584 DOI: 10.1007/s11307-008-0182-z  0.8
2008 Choi CY, Chan DA, Paulmurugan R, Sutphin PD, Le QT, Koong AC, Zundel W, Gambhir SS, Giaccia AJ. Molecular imaging of hypoxia-inducible factor 1 alpha and von Hippel-Lindau interaction in mice. Molecular Imaging. 7: 139-46. PMID 19123984  0.84
2008 Ray S, Paulmurugan R, Patel MR, Ahn BC, Wu L, Carey M, Gambhir SS. Noninvasive imaging of therapeutic gene expression using a bidirectional transcriptional amplification strategy. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 1848-56. PMID 18766175 DOI: 10.1038/mt.2008.180  0.84
2008 Willmann JK, Lutz AM, Paulmurugan R, Patel MR, Chu P, Rosenberg J, Gambhir SS. Dual-targeted contrast agent for US assessment of tumor angiogenesis in vivo. Radiology. 248: 936-44. PMID 18710985 DOI: 10.1148/radiol.2483072231  0.84
2008 Berger F, Paulmurugan R, Bhaumik S, Gambhir SS. Uptake kinetics and biodistribution of 14C-D-luciferin--a radiolabeled substrate for the firefly luciferase catalyzed bioluminescence reaction: impact on bioluminescence based reporter gene imaging. European Journal of Nuclear Medicine and Molecular Imaging. 35: 2275-85. PMID 18661130 DOI: 10.1007/s00259-008-0870-6  0.84
2008 Park S, Ramnarain DB, Hatanpaa KJ, Mickey BE, Saha D, Paulmurugan R, Madden CJ, Wright PS, Bhai S, Ali MA, Puttaparthi K, Hu W, Elliott JL, Stuve O, Habib AA. The death domain-containing kinase RIP1 regulates p27(Kip1) levels through the PI3K-Akt-forkhead pathway. Embo Reports. 9: 766-73. PMID 18566599 DOI: 10.1038/embor.2008.102  0.8
2008 Paulmurugan R, Tamrazi A, Katzenellenbogen JA, Katzenellenbogen BS, Gambhir SS. A human estrogen receptor (ER)alpha mutation with differential responsiveness to nonsteroidal ligands: novel approaches for studying mechanism of ER action. Molecular Endocrinology (Baltimore, Md.). 22: 1552-64. PMID 18451095 DOI: 10.1210/me.2007-0570  0.8
2008 Willmann JK, Chen K, Wang H, Paulmurugan R, Rollins M, Cai W, Wang DS, Chen IY, Gheysens O, Rodriguez-Porcel M, Chen X, Gambhir SS. Monitoring of the biological response to murine hindlimb ischemia with 64Cu-labeled vascular endothelial growth factor-121 positron emission tomography. Circulation. 117: 915-22. PMID 18250264 DOI: 10.1161/CIRCULATIONAHA.107.733220  0.8
2008 Willmann JK, Paulmurugan R, Chen K, Gheysens O, Rodriguez-Porcel M, Lutz AM, Chen IY, Chen X, Gambhir SS. US imaging of tumor angiogenesis with microbubbles targeted to vascular endothelial growth factor receptor type 2 in mice. Radiology. 246: 508-18. PMID 18180339 DOI: 10.1148/radiol.2462070536  0.8
2008 Chan CT, Paulmurugan R, Gheysens OS, Kim J, Chiosis G, Gambhir SS. Molecular imaging of the efficacy of heat shock protein 90 inhibitors in living subjects. Cancer Research. 68: 216-26. PMID 18172314 DOI: 10.1158/0008-5472.CAN-07-2268  0.8
2007 Paulmurugan R, Gambhir SS. Combinatorial library screening for developing an improved split-firefly luciferase fragment-assisted complementation system for studying protein-protein interactions. Analytical Chemistry. 79: 2346-53. PMID 17295448 DOI: 10.1021/ac062053q  0.84
2007 Massoud TF, Paulmurugan R, De A, Ray P, Gambhir SS. Reporter gene imaging of protein-protein interactions in living subjects. Current Opinion in Biotechnology. 18: 31-7. PMID 17254764 DOI: 10.1016/j.copbio.2007.01.007  0.84
2006 Paulmurugan R, Gambhir SS. An intramolecular folding sensor for imaging estrogen receptor-ligand interactions. Proceedings of the National Academy of Sciences of the United States of America. 103: 15883-8. PMID 17043219 DOI: 10.1073/pnas.0607385103  0.84
2006 Padmanabhan P, Otero J, Ray P, Paulmurugan R, Hoffman AR, Gambhir SS, Biswal S, Ulaner GA. Visualization of telomerase reverse transcriptase (hTERT) promoter activity using a trimodality fusion reporter construct. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 47: 270-7. PMID 16455633  0.8
2005 Paulmurugan R, Gambhir SS. Novel fusion protein approach for efficient high-throughput screening of small molecule-mediating protein-protein interactions in cells and living animals. Cancer Research. 65: 7413-20. PMID 16103094 DOI: 10.1158/0008-5472.CAN-05-0588  0.84
2005 Paulmurugan R, Gambhir SS. Firefly luciferase enzyme fragment complementation for imaging in cells and living animals. Analytical Chemistry. 77: 1295-302. PMID 15732910 DOI: 10.1021/ac0484777  0.84
2004 Ray S, Paulmurugan R, Hildebrandt I, Iyer M, Wu L, Carey M, Gambhir SS. Novel bidirectional vector strategy for amplification of therapeutic and reporter gene expression. Human Gene Therapy. 15: 681-90. PMID 15242528 DOI: 10.1089/1043034041361271  0.84
2004 Massoud TF, Paulmurugan R, Gambhir SS. Molecular imaging of homodimeric protein-protein interactions in living subjects. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 18: 1105-7. PMID 15132989 DOI: 10.1096/fj.03-1128fje  0.84
2004 Paulmurugan R, Massoud TF, Huang J, Gambhir SS. Molecular imaging of drug-modulated protein-protein interactions in living subjects. Cancer Research. 64: 2113-9. PMID 15026351  0.84
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