James Patrick Allison
Affiliations: | 1985-1997 | Molecular and Cell Biology | University of California, Berkeley, Berkeley, CA, United States |
| 1997-2004 | Rheumatology | University of California, San Francisco, San Francisco, CA | |
| 2004-2012 | Weill Cornell Medical College, New York, NY, United States | ||
| 2006-2012 | Memorial Sloan-Kettering Cancer Center, Rockville Centre, NY, United States | ||
| 2012- | Immunology | M. D. Anderson Cancer Center, Houston, TX, United States |
Area:
ImmunotherapyWebsite:
https://faculty.mdanderson.org/profiles/james_allison.htmlGoogle:
"James Patrick Allison"Bio:
The Nobel Prize in Physiology or Medicine 2018 was awarded jointly to James P. Allison and Tasuku Honjo "for their discovery of cancer therapy by inhibition of negative immune regulation"
http://www.nasonline.org/member-directory/members/3003904.html
http://www.whatisbiotechnology.org/index.php/people/summary/Allison
https://kingfaisalprize.org/professor-james-p-allison/
http://digitalassets.lib.berkeley.edu/rohoia/ucb/text/oralhisttransretro00maririch.pdf
Cross-listing: Chemistry Tree
Parents
Sign in to add mentor| G Barrie Kitto | grad student | 1973 | UT Austin (Chemistry Tree) | |
| (I. Isolation and characterization of a tumor inhibitory asparaginase from Alcaligenes eutrophus. II. Insolubilization of L-Asparaginase by covalent attachment to nylon tubing.) | ||||
| Ralph Alfred Reisfeld | post-doc | 1974-1977 | Scripps Institute (Chemistry Tree) | |
Children
Sign in to add trainee| Jackson G. Egen | grad student | 2002 | UC Berkeley (Chemistry Tree) |
| Dilnawaz Kapadia | grad student | 2003 | UC Berkeley (Chemistry Tree) |
| Virginia A. Pedicord | grad student | 2010 | Weill Cornell Medical College (Chemistry Tree) |
| Rachel A. Gottschalk | grad student | 2012 | Weill Cornell Medical College (Chemistry Tree) |
| Xiaozhou Fan | grad student | 2013 | Weill Cornell Medical College (Chemistry Tree) |
| Tyler R. Simpson | grad student | 2013 | Weill Cornell Medical College (Chemistry Tree) |
Collaborators
Sign in to add collaborator| Grégoire Altan-Bonnet | collaborator | 2006-2012 | Memorial Sloan Kettering Cancer Center (Chemistry Tree) |
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Publications
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| Sultan H, Takeuchi Y, Ward JP, et al. (2024) Neoantigen-specific cytotoxic Tr1 CD4 T cells suppress cancer immunotherapy. Nature |
| Mok S, Ağaç Çobanoğlu D, Liu H, et al. (2024) Post-immunotherapy CTLA-4 Ig treatment improves antitumor efficacy. Proceedings of the National Academy of Sciences of the United States of America. 121: e2404661121 |
| Siddiqui BA, Palaskas NL, Basu S, et al. (2024) Molecular pathways and cellular subsets associated with adverse clinical outcomes in overlapping immune-related myocarditis and myositis. Cancer Immunology Research |
| Sharma N, Fan X, Atolagbe OT, et al. (2024) ICOS costimulation in combination with CTLA-4 blockade remodels tumor-associated macrophages toward an antitumor phenotype. The Journal of Experimental Medicine. 221 |
| Axelrod ML, Meijers WC, Screever EM, et al. (2022) T cells specific for α-myosin drive immunotherapy-related myocarditis. Nature |
| Hailemichael Y, Johnson DH, Abdel-Wahab N, et al. (2022) Interleukin-6 blockade abrogates immunotherapy toxicity and promotes tumor immunity. Cancer Cell. 40: 509-523.e6 |
| Abbas HA, Hao D, Tomczak K, et al. (2021) Single cell T cell landscape and T cell receptor repertoire profiling of AML in context of PD-1 blockade therapy. Nature Communications. 12: 6071 |
| Sharma N, Atolagbe OT, Ge Z, et al. (2021) LILRB4 suppresses immunity in solid tumors and is a potential target for immunotherapy. The Journal of Experimental Medicine. 218 |
| Goswami S, Chen Y, Anandhan S, et al. (2020) mutation plus CXCL13 expression act as combinatorial biomarkers to predict responses to immune checkpoint therapy in mUCC. Science Translational Medicine. 12 |
| Mitra A, Andrews MC, Roh W, et al. (2020) Spatially resolved analyses link genomic and immune diversity and reveal unfavorable neutrophil activation in melanoma. Nature Communications. 11: 1839 |