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Brent Hartman Cochran, Ph.D. - Publications

Affiliations: 
1985-1993 Biology Massachusetts Institute of Technology, Cambridge, MA, United States 
 1993- Developmental, Molecular, and Chemical Biology Tufts University School of Medicine, Boston, MA, United States 
Area:
signal transduction, glioblastoma, Jak/STAT
Website:
www.cochranlab.org
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32 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Kulkarni S, Goel S, Sengupta S, Cochran BH. A Large-scale RNAi Screen Identifies SGK1 as a Key Survival Kinase for GBM Stem Cells. Molecular Cancer Research : McR. PMID 28993509 DOI: 10.1158/1541-7786.Mcr-17-0146  0.745
2017 Sherry-Lynes MM, Sengupta S, Kulkarni S, Cochran BH. Regulation of the JMJD3 (KDM6B) histone demethylase in glioblastoma stem cells by STAT3. Plos One. 12: e0174775. PMID 28384648 DOI: 10.1371/Journal.Pone.0174775  0.737
2014 Goel-Bhattacharya S, Kulkarni S, Sengupta S, Khagi S, Cochran B. CS-11 * AN RNAi KINOME SCREEN OF GLIOBLASTOMA STEM CELLS UNDER NORMOXIA AND HYPOXIA Neuro-Oncology. 16: v53-v53. DOI: 10.1093/Neuonc/Nou242.11  0.736
2013 Chakraborty S, Li L, Tang H, Xie Y, Puliyappadamba VT, Raisanen J, Burma S, Boothman DA, Cochran B, Wu J, Habib AA. Cytoplasmic TRADD confers a worse prognosis in glioblastoma. Neoplasia (New York, N.Y.). 15: 888-97. PMID 23908590 DOI: 10.1593/Neo.13608  0.31
2009 Sherry MM, Reeves A, Wu JK, Cochran BH. STAT3 is required for proliferation and maintenance of multipotency in glioblastoma stem cells. Stem Cells (Dayton, Ohio). 27: 2383-92. PMID 19658181 DOI: 10.1002/Stem.185  0.708
2008 Simeone-Penney MC, Severgnini M, Rozo L, Takahashi S, Cochran BH, Simon AR. PDGF-induced human airway smooth muscle cell proliferation requires STAT3 and the small GTPase Rac1. American Journal of Physiology. Lung Cellular and Molecular Physiology. 294: L698-704. PMID 18310224 DOI: 10.1152/ajplung.00529.2007  0.325
2005 Konnikova L, Simeone MC, Kruger MM, Kotecki M, Cochran BH. Signal transducer and activator of transcription 3 (STAT3) regulates human telomerase reverse transcriptase (hTERT) expression in human cancer and primary cells. Cancer Research. 65: 6516-20. PMID 16061629 DOI: 10.1158/0008-5472.Can-05-0924  0.669
2003 Konnikova L, Kotecki M, Kruger MM, Cochran BH. Knockdown of STAT3 expression by RNAi induces apoptosis in astrocytoma cells. Bmc Cancer. 3: 23. PMID 13678425 DOI: 10.1186/1471-2407-3-23  0.671
2001 Kim DW, Cochran BH. JAK2 activates TFII-I and regulates its interaction with extracellular signal-regulated kinase. Molecular and Cellular Biology. 21: 3387-97. PMID 11313464 DOI: 10.1128/Mcb.21.10.3387-3397.2000  0.445
2000 Simon AR, Vikis HG, Stewart S, Fanburg BL, Cochran BH, Guan KL. Regulation of STAT3 by direct binding to the Rac1 GTPase. Science (New York, N.Y.). 290: 144-7. PMID 11021801 DOI: 10.1126/Science.290.5489.144  0.302
1998 Simon AR, Rai U, Fanburg BL, Cochran BH. Activation of the JAK-STAT pathway by reactive oxygen species. The American Journal of Physiology. 275: C1640-52. PMID 9843726  0.327
1993 Meyer DJ, Stephenson EW, Johnson L, Cochran BH, Schwartz J. The serum response element can mediate induction of c-fos by growth hormone. Proceedings of the National Academy of Sciences of the United States of America. 90: 6721-5. PMID 8341690 DOI: 10.1073/Pnas.90.14.6721  0.328
1993 Cochran BH. Regulation of immediate early gene expression. Nida Research Monograph. 125: 3-24. PMID 8341367  0.309
1991 Sengupta P, Cochran BH. MAT alpha 1 can mediate gene activation by a-mating factor. Genes & Development. 5: 1924-34. PMID 1916267  0.471
1990 Sacca R, Cochran BH. Identification of a PDGF-responsive element in the murine c-myc gene. Oncogene. 5: 1499-505. PMID 2250909  0.401
1990 Sengupta P, Cochran BH. The PRE and PQ box are functionally distinct yeast pheromone response elements. Molecular and Cellular Biology. 10: 6809-12. PMID 2247085  0.53
1990 Gurland G, Ashcom G, Cochran BH, Schwartz J. Rapid events in growth hormone action. Induction of c-fos and c-jun transcription in 3T3-F442A preadipocytes. Endocrinology. 127: 3187-95. PMID 2123448 DOI: 10.1210/Endo-127-6-3187  0.334
1988 Hayes TE, Sengupta P, Cochran BH. The human c-fos serum response factor and the yeast factors GRM/PRTF have related DNA-binding specificities. Genes & Development. 2: 1713-22. PMID 3071491  0.57
1988 Cochran BH, Townes J, Hayes TE. Transcriptional regulation of competence genes in Balb/c-3T3 cells. Progress in Clinical and Biological Research. 284: 225-41. PMID 3064103  0.373
1987 Hayes TE, Kitchen AM, Cochran BH. A rapidly inducible DNA-binding activity which binds upstream of the c-fos proto-oncogene. Journal of Cellular Physiology. Supplement. 63-8. PMID 3119603  0.371
1987 Hayes TE, Kitchen AM, Cochran BH. Inducible binding of a factor to the c-fos regulatory region. Proceedings of the National Academy of Sciences of the United States of America. 84: 1272-6. PMID 3029776  0.375
1987 Cochran BH, Zumstein P, Zullo J, Rollins B, Mercola M, Stiles CD. Differential colony hybridization: molecular cloning from a zero data base. Methods in Enzymology. 147: 64-85. PMID 2444861 DOI: 10.1016/0076-6879(87)47099-7  0.671
1985 Callahan M, Cochran BH, Stiles CD. The PDGF-inducible 'competence genes': intracellular mediators of the mitogenic response. Ciba Foundation Symposium. 116: 87-97. PMID 4075904 DOI: 10.1002/9780470720974.ch6  0.616
1985 Zullo JN, Cochran BH, Huang AS, Stiles CD. Platelet-derived growth factor and double-stranded ribonucleic acids stimulate expression of the same genes in 3T3 cells. Cell. 43: 793-800. PMID 3000615 DOI: 10.1016/0092-8674(85)90252-1  0.658
1984 Hendrickson SL, Cochran BH, Reffel AC, Stiles CD. Regulation of gene expression by serum and serum growth factors. Symposium On Fundamental Cancer Research. 37: 71-85. PMID 6335592  0.572
1984 Kelly K, Cochran B, Stiles C, Leder P. The regulation of c-myc by growth signals. Current Topics in Microbiology and Immunology. 113: 117-26. PMID 6332711 DOI: 10.1007/978-3-642-69860-6_22  0.636
1984 Cochran BH, Zullo J, Verma IM, Stiles CD. Expression of the c-fos gene and of an fos-related gene is stimulated by platelet-derived growth factor. Science (New York, N.Y.). 226: 1080-2. PMID 6093261 DOI: 10.1126/Science.6093261  0.642
1984 Armelin HA, Armelin MC, Kelly K, Stewart T, Leder P, Cochran BH, Stiles CD. Functional role for c-myc in mitogenic response to platelet-derived growth factor. Nature. 310: 655-60. PMID 6088986 DOI: 10.1038/310655A0  0.657
1984 Cochran BH, Kelly K, Leder P, Stiles CD. Molecular action of platelet-derived growth factor: Insights to oncogene function Federation Proceedings. 43: no. 3265.  0.522
1983 Cochran BH, Reffel AC, Stiles CD. Molecular cloning of gene sequences regulated by platelet-derived growth factor. Cell. 33: 939-47. PMID 6872001 DOI: 10.1016/0092-8674(83)90037-5  0.64
1983 Kelly K, Cochran BH, Stiles CD, Leder P. Cell-specific regulation of the c-myc gene by lymphocyte mitogens and platelet-derived growth factor. Cell. 35: 603-10. PMID 6606489 DOI: 10.1016/0092-8674(83)90092-2  0.652
1981 Cochran BH, Lillquist JS, Stiles CD. Post-transcriptional control of protein synthesis in Balb/c-3T3 cells by platelet-derived growth factor and platelet-poor plasma. Journal of Cellular Physiology. 109: 429-38. PMID 6798044 DOI: 10.1002/Jcp.1041090308  0.602
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