| Year |
Citation |
Score |
| 2024 |
Ureña E, Xu B, Regan JC, Atilano ML, Minkley LJ, Filer D, Lu YX, Bolukbasi E, Khericha M, Alic N, Partridge L. Trametinib ameliorates aging-associated gut pathology in females by reducing Pol III activity in intestinal stem cells. Proceedings of the National Academy of Sciences of the United States of America. 121: e2311313121. PMID 38241436 DOI: 10.1073/pnas.2311313121 |
0.798 |
|
| 2023 |
Debès C, Papadakis A, Grönke S, Karalay Ö, Tain LS, Mizi A, Nakamura S, Hahn O, Weigelt C, Josipovic N, Zirkel A, Brusius I, Sofiadis K, Lamprousi M, Lu YX, ... ... Partridge L, et al. Ageing-associated changes in transcriptional elongation influence longevity. Nature. PMID 37046086 DOI: 10.1038/s41586-023-05922-y |
0.764 |
|
| 2022 |
Regan JC, Lu YX, Ureña E, Meilenbrock RL, Catterson JH, Kißler D, Fröhlich J, Funk E, Partridge L. Sexual identity of enterocytes regulates autophagy to determine intestinal health, lifespan and responses to rapamycin. Nature Aging. 2: 1145-1158. PMID 37118538 DOI: 10.1038/s43587-022-00308-7 |
0.8 |
|
| 2022 |
Juricic P, Lu YX, Leech T, Drews LF, Paulitz J, Lu J, Nespital T, Azami S, Regan JC, Funk E, Fröhlich J, Grönke S, Partridge L. Long-lasting geroprotection from brief rapamycin treatment in early adulthood by persistently increased intestinal autophagy. Nature Aging. 2: 824-836. PMID 37118497 DOI: 10.1038/s43587-022-00278-w |
0.779 |
|
| 2022 |
Laskovs M, Partridge L, Slack C. Molecular inhibition of RAS signalling to target ageing and age-related health. Disease Models & Mechanisms. 15. PMID 36111627 DOI: 10.1242/dmm.049627 |
0.743 |
|
| 2022 |
Meron E, Thaysen M, Angeli S, Antebi A, Barzilai N, Baur JA, Bekker-Jensen S, Birkisdottir M, Bischof E, Bruening J, Brunet A, Buchwalter A, Cabreiro F, Cai S, Chen BH, ... ... Partridge L, et al. Meeting Report: Aging Research and Drug Discovery. Aging. 14. PMID 35089871 DOI: 10.18632/aging.203859 |
0.743 |
|
| 2021 |
Aman Y, Schmauck-Medina T, Hansen M, Morimoto RI, Simon AK, Bjedov I, Palikaras K, Simonsen A, Johansen T, Tavernarakis N, Rubinsztein DC, Partridge L, Kroemer G, Labbadia J, Fang EF. Autophagy in healthy aging and disease. Nature Aging. 1: 634-650. PMID 34901876 DOI: 10.1038/s43587-021-00098-4 |
0.722 |
|
| 2021 |
Lu YX, Regan JC, Eßer J, Drews LF, Weinseis T, Stinn J, Hahn O, Miller RA, Grönke S, Partridge L. A TORC1-histone axis regulates chromatin organisation and non-canonical induction of autophagy to ameliorate ageing. Elife. 10. PMID 33988501 DOI: 10.7554/eLife.62233 |
0.782 |
|
| 2020 |
Bjedov I, Cochemé HM, Foley A, Wieser D, Woodling NS, Castillo-Quan JI, Norvaisas P, Lujan C, Regan J, Toivonen JM, Murphy MP, Thornton J, Kinghorn KJ, Neufeld TP, Cabreiro F, ... Partridge L, et al. Fine-tuning autophagy maximises lifespan and is associated with changes in mitochondrial gene expression in Drosophila. Plos Genetics. 16: e1009083. PMID 33253201 DOI: 10.1371/journal.pgen.1009083 |
0.803 |
|
| 2020 |
Woodling NS, Rajasingam A, Minkley LJ, Rizzo A, Partridge L. Independent glial subtypes delay development and extend healthy lifespan upon reduced insulin-PI3K signalling. Bmc Biology. 18: 124. PMID 32928209 DOI: 10.1186/s12915-020-00854-9 |
0.393 |
|
| 2020 |
Weigelt CM, Sehgal R, Tain LS, Cheng J, Eßer J, Pahl A, Dieterich C, Grönke S, Partridge L. An Insulin-Sensitive Circular RNA that Regulates Lifespan in Drosophila. Molecular Cell. PMID 32592682 DOI: 10.1016/j.molcel.2020.06.011 |
0.379 |
|
| 2020 |
Yu Y, Niccoli T, Ren Z, Woodling NS, Aleyakpo B, Szabadkai G, Partridge L. PICALM rescues glutamatergic neurotransmission, behavioural function, and survival in a Drosophila model of Aβ42 toxicity. Human Molecular Genetics. PMID 32592479 DOI: 10.1093/Hmg/Ddaa125 |
0.562 |
|
| 2020 |
Partridge L, Fuentealba M, Kennedy BK. The quest to slow ageing through drug discovery. Nature Reviews. Drug Discovery. PMID 32467649 DOI: 10.1038/S41573-020-0067-7 |
0.351 |
|
| 2020 |
Woodling NS, Aleyakpo B, Dyson MC, Minkley LJ, Rajasingam A, Dobson AJ, Leung KHC, Pomposova S, Fuentealba M, Alic N, Partridge L. The neuronal receptor tyrosine kinase Alk is a target for longevity. Aging Cell. e13137. PMID 32291952 DOI: 10.1111/Acel.13137 |
0.716 |
|
| 2019 |
Morón-Oset J, Supèr T, Esser J, Isaacs AM, Grönke S, Partridge L. Glycine-alanine dipeptide repeats spread rapidly in a repeat length- and age-dependent manner in the fly brain. Acta Neuropathologica Communications. 7: 209. PMID 31843021 DOI: 10.1186/s40478-019-0860-x |
0.317 |
|
| 2019 |
Hahn O, Drews LF, Nguyen A, Tatsuta T, Gkioni L, Hendrich O, Zhang Q, Langer T, Pletcher S, Wakelam MJO, Beyer A, Grönke S, Partridge L. A nutritional memory effect counteracts benefits of dietary restriction in old mice. Nature Metabolism. 1: 1059-1073. PMID 31742247 DOI: 10.1038/s42255-019-0121-0 |
0.553 |
|
| 2019 |
Tain LS, Jain C, Nespital T, Froehlich J, Hinze Y, Grönke S, Partridge L. Longevity in response to lowered insulin signaling requires glycine N-methyltransferase-dependent spermidine production. Aging Cell. e13043. PMID 31721422 DOI: 10.1111/acel.13043 |
0.381 |
|
| 2019 |
Castillo-Quan JI, Tain LS, Kinghorn KJ, Li L, Grönke S, Hinze Y, Blackwell TK, Bjedov I, Partridge L. A triple drug combination targeting components of the nutrient-sensing network maximizes longevity. Proceedings of the National Academy of Sciences of the United States of America. PMID 31570569 DOI: 10.1073/Pnas.1913212116 |
0.738 |
|
| 2019 |
Juricic P, Grönke S, Partridge L. Branched-chain amino acids have equivalent effects to other essential amino acids on lifespan and ageing-related traits in Drosophila. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 30891588 DOI: 10.1093/gerona/glz080 |
0.358 |
|
| 2019 |
Fuentealba M, Dönertaş HM, Williams R, Labbadia J, Thornton JM, Partridge L. Using the drug-protein interactome to identify anti-ageing compounds for humans. Plos Computational Biology. 15: e1006639. PMID 30625143 DOI: 10.1371/Journal.Pcbi.1006639 |
0.329 |
|
| 2019 |
Partridge L, Prowse N. The effects of reproduction on longevity and fertility in male Drosophila melanogaster. Journal of Insect Physiology. 43: 501-512. PMID 12770412 DOI: 10.1016/S0022-1910(97)00014-0 |
0.336 |
|
| 2018 |
Dönertaş HM, Fuentealba M, Partridge L, Thornton JM. Identifying Potential Ageing-Modulating Drugs In Silico. Trends in Endocrinology and Metabolism: Tem. PMID 30581056 DOI: 10.1016/J.Tem.2018.11.005 |
0.335 |
|
| 2018 |
Hahn O, Stubbs TM, Reik W, Grönke S, Beyer A, Partridge L. Hepatic gene body hypermethylation is a shared epigenetic signature of murine longevity. Plos Genetics. 14: e1007766. PMID 30462643 DOI: 10.1371/Journal.Pgen.1007766 |
0.331 |
|
| 2018 |
Kauppila TES, Bratic A, Jensen MB, Baggio F, Partridge L, Jasper H, Grönke S, Larsson NG. Mutations of mitochondrial DNA are not major contributors to aging of fruit flies. Proceedings of the National Academy of Sciences of the United States of America. PMID 30249665 DOI: 10.1073/Pnas.1721683115 |
0.308 |
|
| 2018 |
Partridge L, Deelen J, Slagboom PE. Facing up to the global challenges of ageing. Nature. 561: 45-56. PMID 30185958 DOI: 10.1038/s41586-018-0457-8 |
0.31 |
|
| 2018 |
Flatt T, Partridge L. Horizons in the evolution of aging. Bmc Biology. 16: 93. PMID 30124168 DOI: 10.1186/S12915-018-0562-Z |
0.376 |
|
| 2018 |
Dönertaş HM, Fuentealba Valenzuela M, Partridge L, Thornton JM. Gene Expression-Based Drug Repurposing to Target Ageing. Aging Cell. e12819. PMID 29959820 DOI: 10.1111/Acel.12819 |
0.346 |
|
| 2018 |
Catterson JH, Khericha M, Dyson MC, Vincent AJ, Callard R, Haveron SM, Rajasingam A, Ahmad M, Partridge L. Short-Term, Intermittent Fasting Induces Long-Lasting Gut Health and TOR-Independent Lifespan Extension. Current Biology : Cb. PMID 29779873 DOI: 10.1016/j.cub.2018.04.015 |
0.349 |
|
| 2018 |
Augustin H, McGourty K, Allen MJ, Adcott J, Wong CT, Boucrot E, Partridge L. Impact of insulin signaling and proteasomal activity on physiological output of a neuronal circuit in aging Drosophila melanogaster. Neurobiology of Aging. 66: 149-157. PMID 29579685 DOI: 10.1016/J.Neurobiolaging.2018.02.027 |
0.38 |
|
| 2017 |
Bolukbasi E, Khericha M, Regan JC, Ivanov DK, Adcott J, Dyson MC, Nespital T, Thornton JM, Alic N, Partridge L. Intestinal Fork Head Regulates Nutrient Absorption and Promotes Longevity. Cell Reports. 21: 641-653. PMID 29045833 DOI: 10.1016/J.Celrep.2017.09.042 |
0.811 |
|
| 2017 |
Niccoli T, Partridge L, Isaacs AM. Ageing as a risk factor for ALS/FTD. Human Molecular Genetics. 26: R105-R113. PMID 28977441 DOI: 10.1093/hmg/ddx247 |
0.356 |
|
| 2017 |
Piper MDW, Partridge L. Drosophila as a model for ageing. Biochimica Et Biophysica Acta. PMID 28964875 DOI: 10.1016/J.Bbadis.2017.09.016 |
0.408 |
|
| 2017 |
Tain LS, Sehlke R, Jain C, Chokkalingam M, Nagaraj N, Essers P, Rassner M, Grönke S, Froelich J, Dieterich C, Mann M, Alic N, Beyer A, Partridge L. A proteomic atlas of insulin signalling reveals tissue-specific mechanisms of longevity assurance. Molecular Systems Biology. 13: 939. PMID 28916541 DOI: 10.15252/Msb.20177663 |
0.72 |
|
| 2017 |
Augustin H, McGourty K, Allen MJ, Madem SK, Adcott J, Kerr F, Wong CT, Vincent A, Godenschwege T, Boucrot E, Partridge L. Reduced insulin signaling maintains electrical transmission in a neural circuit in aging flies. Plos Biology. 15: e2001655. PMID 28902870 DOI: 10.1371/Journal.Pbio.2001655 |
0.379 |
|
| 2017 |
Augustin H, Adcott J, Elliott CJH, Partridge L. Complex Roles of Myoglianin in Regulating Adult Performance and Lifespan. Fly. 0. PMID 28837401 DOI: 10.1080/19336934.2017.1369638 |
0.368 |
|
| 2017 |
Bustos V, Partridge L. Good Ol' Fat: Links between Lipid Signaling and Longevity. Trends in Biochemical Sciences. PMID 28802547 DOI: 10.1016/j.tibs.2017.07.001 |
0.358 |
|
| 2017 |
Brandt T, Mourier A, Tain LS, Partridge L, Larsson NG, Kühlbrandt W. Changes of mitochondrial ultrastructure and function during ageing in mice and Drosophila. Elife. 6. PMID 28699890 DOI: 10.7554/Elife.24662 |
0.332 |
|
| 2017 |
Ziehm M, Kaur S, Ivanov DK, Ballester PJ, Marcus D, Partridge L, Thornton JM. Drug repurposing for aging research using model organisms. Aging Cell. PMID 28620943 DOI: 10.1111/Acel.12626 |
0.361 |
|
| 2017 |
Hahn O, Grönke S, Stubbs TM, Ficz G, Hendrich O, Krueger F, Andrews S, Zhang Q, Wakelam MJ, Beyer A, Reik W, Partridge L. Dietary restriction protects from age-associated DNA methylation and induces epigenetic reprogramming of lipid metabolism. Genome Biology. 18: 56. PMID 28351387 DOI: 10.1186/S13059-017-1187-1 |
0.354 |
|
| 2017 |
Piper MD, Soultoukis GA, Blanc E, Mesaros A, Herbert SL, Juricic P, He X, Atanassov I, Salmonowicz H, Yang M, Simpson SJ, Ribeiro C, Partridge L. Matching Dietary Amino Acid Balance to the In Silico-Translated Exome Optimizes Growth and Reproduction without Cost to Lifespan. Cell Metabolism. 25: 610-621. PMID 28273481 DOI: 10.1016/J.Cmet.2017.02.005 |
0.67 |
|
| 2016 |
Tiku V, Jain C, Raz Y, Nakamura S, Heestand B, Liu W, Späth M, Suchiman HED, Müller RU, Slagboom PE, Partridge L, Antebi A. Small nucleoli are a cellular hallmark of longevity. Nature Communications. 8: 16083. PMID 28853436 DOI: 10.1038/ncomms16083 |
0.375 |
|
| 2016 |
Kinghorn KJ, Grönke S, Castillo-Quan JI, Woodling NS, Li L, Sirka E, Gegg M, Mills K, Hardy J, Bjedov I, Partridge L. A Drosophila Model of Neuronopathic Gaucher Disease Demonstrates Lysosomal-Autophagic Defects and Altered mTOR Signalling and Is Functionally Rescued by Rapamycin. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 11654-11670. PMID 27852774 DOI: 10.1523/Jneurosci.4527-15.2016 |
0.725 |
|
| 2016 |
Piper MD, Partridge L. Protocols to Study Aging in Drosophila. Methods in Molecular Biology (Clifton, N.J.). 1478: 291-302. PMID 27730590 DOI: 10.1007/978-1-4939-6371-3_18 |
0.7 |
|
| 2016 |
Kakanj P, Moussian B, Grönke S, Bustos V, Eming SA, Partridge L, Leptin M. Insulin and TOR signal in parallel through FOXO and S6K to promote epithelial wound healing. Nature Communications. 7: 12972. PMID 27713427 DOI: 10.1038/ncomms12972 |
0.341 |
|
| 2016 |
Essers P, Tain LS, Nespital T, Goncalves J, Froehlich J, Partridge L. Reduced insulin/insulin-like growth factor signaling decreases translation in Drosophila and mice. Scientific Reports. 6: 30290. PMID 27452396 DOI: 10.1038/srep30290 |
0.357 |
|
| 2016 |
Soultoukis GA, Partridge L. Dietary Protein, Metabolism, and Aging. Annual Review of Biochemistry. PMID 27145842 DOI: 10.1146/annurev-biochem-060815-014422 |
0.387 |
|
| 2016 |
Castillo-Quan JI, Li L, Kinghorn KJ, Ivanov DK, Tain LS, Slack C, Kerr F, Nespital T, Thornton J, Hardy J, Bjedov I, Partridge L. Lithium Promotes Longevity through GSK3/NRF2-Dependent Hormesis. Cell Reports. PMID 27068460 DOI: 10.1016/J.Celrep.2016.03.041 |
0.801 |
|
| 2016 |
Burnouf S, Grönke S, Augustin H, Dols J, Gorsky MK, Werner J, Kerr F, Alic N, Martinez P, Partridge L. Deletion of endogenous Tau proteins is not detrimental in Drosophila. Scientific Reports. 6: 23102. PMID 26976084 DOI: 10.1038/Srep23102 |
0.668 |
|
| 2016 |
Regan JC, Khericha M, Dobson AJ, Bolukbasi E, Rattanavirotkul N, Partridge L. Sex difference in pathology of the ageing gut mediates the greater response of female lifespan to dietary restriction. Elife. 5. PMID 26878754 DOI: 10.7554/eLife.10956 |
0.725 |
|
| 2016 |
Afschar S, Toivonen JM, Hoffmann JM, Tain LS, Wieser D, Finlayson AJ, Driege Y, Alic N, Emran S, Stinn J, Froehlich J, Piper MD, Partridge L. Nuclear hormone receptor DHR96 mediates the resistance to xenobiotics but not the increased lifespan of insulin-mutant Drosophila. Proceedings of the National Academy of Sciences of the United States of America. PMID 26787908 DOI: 10.1073/Pnas.1515137113 |
0.801 |
|
| 2016 |
Kinghorn K, Gronke S, Castillo-Quan JI, Li L, Woodling N, Sirka E, Gegg M, Hardy J, Partridge L. A NOVEL MODEL OF GBA1-ASSOCIATED PARKINSON'S DISEASE IMPLICATES AUTOPHAGY Journal of Neurology, Neurosurgery & Psychiatry. 87: e1.68-e1. DOI: 10.1136/Jnnp-2016-315106.16 |
0.301 |
|
| 2015 |
Kerr F, Augustin H, Piper MDW, Gandy C, Allen MJ, Lovestone S, Partridge L. Erratum to "Dietary restriction delays aging, but not neuronal dysfunction, in Drosophila models of Alzheimer's disease." [Neurobiol. Aging 32 (2011) 1977-1989]. Neurobiology of Aging. 36: 2331. PMID 28843333 DOI: 10.1016/J.Neurobiolaging.2015.05.007 |
0.324 |
|
| 2015 |
Armanios M, de Cabo R, Mannick J, Partridge L, van Deursen J, Villeda S. Translational strategies in aging and age-related disease. Nature Medicine. 21: 1395-9. PMID 26646495 DOI: 10.1038/Nm.4004 |
0.324 |
|
| 2015 |
Slack C, Alic N, Partridge L. Could cancer drugs provide ammunition against ageing? Cell Cycle (Georgetown, Tex.). 0. PMID 26587873 DOI: 10.1080/15384101.2015.1118905 |
0.769 |
|
| 2015 |
Hoffmann JM, Partridge L. Nuclear hormone receptors: Roles of xenobiotic detoxification and sterol homeostasis in healthy aging. Critical Reviews in Biochemistry and Molecular Biology. 50: 380-92. PMID 26383043 DOI: 10.3109/10409238.2015.1067186 |
0.385 |
|
| 2015 |
Slack C, Alic N, Foley A, Cabecinha M, Hoddinott MP, Partridge L. The Ras-Erk-ETS-Signaling Pathway Is a Drug Target for Longevity. Cell. 162: 72-83. PMID 26119340 DOI: 10.1016/J.Cell.2015.06.023 |
0.786 |
|
| 2015 |
Menger KE, James AM, Cochemé HM, Harbour ME, Chouchani ET, Ding S, Fearnley IM, Partridge L, Murphy MP. Fasting, but Not Aging, Dramatically Alters the Redox Status of Cysteine Residues on Proteins in Drosophila melanogaster. Cell Reports. 11: 1856-65. PMID 26095360 DOI: 10.1016/j.celrep.2015.05.033 |
0.302 |
|
| 2015 |
Ivanov DK, Escott-Price V, Ziehm M, Magwire MM, Mackay TF, Partridge L, Thornton JM. Longevity GWAS Using the Drosophila Genetic Reference Panel. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 25922346 DOI: 10.1093/Gerona/Glv047 |
0.325 |
|
| 2015 |
Fontana L, Partridge L. Promoting health and longevity through diet: from model organisms to humans. Cell. 161: 106-18. PMID 25815989 DOI: 10.1016/j.cell.2015.02.020 |
0.361 |
|
| 2015 |
Alic N, Partridge L. Myc mouse and anti-ageing therapy. Trends in Endocrinology and Metabolism: Tem. 26: 163-4. PMID 25727046 DOI: 10.1016/J.Tem.2015.02.005 |
0.702 |
|
| 2015 |
Piper MDW, Blanc E, Leitão-Gonçalves R, Yang M, He X, Linford NJ, Hoddinott MP, Hopfen C, Soultoukis GA, Niemeyer C, Kerr F, Pletcher SD, Ribeiro C, Partridge L. Erratum: Corrigendum: A holidic medium for Drosophila melanogaster Nature Methods. 12: 1098-1098. DOI: 10.1038/Nmeth1115-1098D |
0.552 |
|
| 2014 |
Piper MD, Selman C, Speakman JR, Partridge L. Using doubly-labeled water to measure energy expenditure in an important small ectotherm Drosophila melanogaster. Journal of Genetics and Genomics = Yi Chuan Xue Bao. 41: 505-12. PMID 25269676 DOI: 10.1016/J.Jgg.2014.07.004 |
0.669 |
|
| 2014 |
Alic N, Giannakou ME, Papatheodorou I, Hoddinott MP, Andrews TD, Bolukbasi E, Partridge L. Interplay of dFOXO and two ETS-family transcription factors determines lifespan in Drosophila melanogaster. Plos Genetics. 10: e1004619. PMID 25232726 DOI: 10.1371/Journal.Pgen.1004619 |
0.696 |
|
| 2014 |
Partridge L. Intervening in ageing to prevent the diseases of ageing. Trends in Endocrinology and Metabolism: Tem. 25: 555-7. PMID 25175302 DOI: 10.1016/j.tem.2014.08.003 |
0.371 |
|
| 2014 |
Sofola-Adesakin O, Castillo-Quan JI, Rallis C, Tain LS, Bjedov I, Rogers I, Li L, Martinez P, Khericha M, Cabecinha M, Bähler J, Partridge L. Lithium suppresses Aβ pathology by inhibiting translation in an adult Drosophila model of Alzheimer's disease. Frontiers in Aging Neuroscience. 6: 190. PMID 25126078 DOI: 10.3389/Fnagi.2014.00190 |
0.713 |
|
| 2014 |
Alic N, Tullet JM, Niccoli T, Broughton S, Hoddinott MP, Slack C, Gems D, Partridge L. Cell-nonautonomous effects of dFOXO/DAF-16 in aging. Cell Reports. 6: 608-16. PMID 24508462 DOI: 10.1016/J.Celrep.2014.01.015 |
0.805 |
|
| 2014 |
Piper MD, Blanc E, Leitão-Gonçalves R, Yang M, He X, Linford NJ, Hoddinott MP, Hopfen C, Soultoukis GA, Niemeyer C, Kerr F, Pletcher SD, Ribeiro C, Partridge L. A holidic medium for Drosophila melanogaster. Nature Methods. 11: 100-5. PMID 24240321 DOI: 10.1038/Nmeth.2731 |
0.745 |
|
| 2014 |
Piper MDW, Blanc E, Leitão-Gonçalves R, Yang M, He X, Linford NJ, Hoddinott MP, Hopfen C, Soultoukis GA, Niemeyer C, Kerr F, Pletcher SD, Ribeiro C, Partridge L. Corrigendum: A holidic medium for Drosophila melanogaster (Nature Methods (2014) 11, (100-105)) Nature Methods. 11: 971. DOI: 10.1038/Nmeth0914-971C |
0.537 |
|
| 2013 |
Regan JC, Partridge L. Gender and longevity: why do men die earlier than women? Comparative and experimental evidence. Best Practice & Research. Clinical Endocrinology & Metabolism. 27: 467-79. PMID 24054925 DOI: 10.1016/j.beem.2013.05.016 |
0.708 |
|
| 2013 |
Metaxakis A, Partridge L. Dietary restriction extends lifespan in wild-derived populations of Drosophila melanogaster. Plos One. 8: e74681. PMID 24040317 DOI: 10.1371/journal.pone.0074681 |
0.311 |
|
| 2013 |
López-Otín C, Blasco MA, Partridge L, Serrano M, Kroemer G. The hallmarks of aging. Cell. 153: 1194-217. PMID 23746838 DOI: 10.1016/J.Cell.2013.05.039 |
0.382 |
|
| 2013 |
Lee SF, Eyre-Walker YC, Rane RV, Reuter C, Vinti G, Rako L, Partridge L, Hoffmann AA. Polymorphism in the neurofibromin gene, Nf1, is associated with antagonistic selection on wing size and development time in Drosophila melanogaster. Molecular Ecology. 22: 2716-25. PMID 23506114 DOI: 10.1111/Mec.12301 |
0.423 |
|
| 2013 |
Gems D, Partridge L. Genetics of longevity in model organisms: debates and paradigm shifts. Annual Review of Physiology. 75: 621-44. PMID 23190075 DOI: 10.1146/annurev-physiol-030212-183712 |
0.408 |
|
| 2013 |
Piper M, Partridge L. Preparation of a holidic medium for Drosophila melanogaster Protocol Exchange. DOI: 10.1038/Protex.2013.082 |
0.635 |
|
| 2013 |
Slack C, Partridge L. Genes, pathways and metabolism in ageing Drug Discovery Today: Disease Models. 10: e87-e93. DOI: 10.1016/j.ddmod.2013.01.002 |
0.404 |
|
| 2012 |
Partridge L. Diet and healthy aging. The New England Journal of Medicine. 367: 2550-1. PMID 23268671 DOI: 10.1056/NEJMcibr1210447 |
0.308 |
|
| 2012 |
Papatheodorou I, Ziehm M, Wieser D, Alic N, Partridge L, Thornton JM. Using answer set programming to integrate RNA expression with signalling pathway information to infer how mutations affect ageing. Plos One. 7: e50881. PMID 23251396 DOI: 10.1371/Journal.Pone.0050881 |
0.71 |
|
| 2012 |
Slack C, Foley A, Partridge L. Activation of AMPK by the putative dietary restriction mimetic metformin is insufficient to extend lifespan in Drosophila. Plos One. 7: e47699. PMID 23077661 DOI: 10.1371/journal.pone.0047699 |
0.757 |
|
| 2012 |
Alic N, Hoddinott MP, Foley A, Slack C, Piper MD, Partridge L. Detrimental effects of RNAi: a cautionary note on its use in Drosophila ageing studies. Plos One. 7: e45367. PMID 23028964 DOI: 10.1371/Journal.Pone.0045367 |
0.799 |
|
| 2012 |
Gioti A, Wigby S, Wertheim B, Schuster E, Martinez P, Pennington CJ, Partridge L, Chapman T. Sex peptide of Drosophila melanogaster males is a global regulator of reproductive processes in females. Proceedings. Biological Sciences / the Royal Society. 279: 4423-32. PMID 22977156 DOI: 10.1098/Rspb.2012.1634 |
0.73 |
|
| 2012 |
Niccoli T, Partridge L. Ageing as a risk factor for disease. Current Biology : Cb. 22: R741-52. PMID 22975005 DOI: 10.1016/j.cub.2012.07.024 |
0.399 |
|
| 2012 |
Rogers I, Kerr F, Martinez P, Hardy J, Lovestone S, Partridge L. Ageing increases vulnerability to aβ42 toxicity in Drosophila. Plos One. 7: e40569. PMID 22808195 DOI: 10.1371/Journal.Pone.0040569 |
0.345 |
|
| 2012 |
Barzilai N, Guarente L, Kirkwood TB, Partridge L, Rando TA, Slagboom PE. The place of genetics in ageing research. Nature Reviews. Genetics. 13: 589-94. PMID 22777128 DOI: 10.1038/Nrg3290 |
0.346 |
|
| 2012 |
Chen Y, Lee SF, Blanc E, Reuter C, Wertheim B, Martinez-Diaz P, Hoffmann AA, Partridge L. Genome-wide transcription analysis of clinal genetic variation in Drosophila. Plos One. 7: e34620. PMID 22514645 DOI: 10.1371/Journal.Pone.0034620 |
0.458 |
|
| 2012 |
Selman C, Partridge L. A double whammy for aging? Rapamycin extends lifespan and inhibits cancer in inbred female mice. Cell Cycle (Georgetown, Tex.). 11: 17-8. PMID 22186783 DOI: 10.4161/cc.11.1.18736 |
0.315 |
|
| 2012 |
Kerr F, Rogers I, Martinez P, Hardy J, Lovestone S, Partridge L. Ageing increases vulnerability to Aβ42 toxicity in drosophila Alzheimers & Dementia. 8: 202. DOI: 10.1016/J.Jalz.2012.05.554 |
0.334 |
|
| 2012 |
Partridge L. Nutrient Sensing Pathways and Ageing Free Radical Biology and Medicine. 53: S3. DOI: 10.1016/j.freeradbiomed.2012.08.073 |
0.361 |
|
| 2011 |
Burnett C, Valentini S, Cabreiro F, Goss M, Somogyvári M, Piper MD, Hoddinott M, Sutphin GL, Leko V, McElwee JJ, Vazquez-Manrique RP, Orfila AM, Ackerman D, Au C, Vinti G, ... ... Partridge L, et al. Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila. Nature. 477: 482-5. PMID 21938067 DOI: 10.1038/Nature10296 |
0.701 |
|
| 2011 |
Alic N, Partridge L. Death and dessert: nutrient signalling pathways and ageing. Current Opinion in Cell Biology. 23: 738-43. PMID 21835601 DOI: 10.1016/J.Ceb.2011.07.006 |
0.725 |
|
| 2011 |
Piper MD, Partridge L, Raubenheimer D, Simpson SJ. Dietary restriction and aging: a unifying perspective. Cell Metabolism. 14: 154-60. PMID 21803286 DOI: 10.1016/J.Cmet.2011.06.013 |
0.711 |
|
| 2011 |
Alic N, Andrews TD, Giannakou ME, Papatheodorou I, Slack C, Hoddinott MP, Cochemé HM, Schuster EF, Thornton JM, Partridge L. Genome-wide dFOXO targets and topology of the transcriptomic response to stress and insulin signalling. Molecular Systems Biology. 7: 502. PMID 21694719 DOI: 10.1038/Msb.2011.36 |
0.797 |
|
| 2011 |
Slack C, Giannakou ME, Foley A, Goss M, Partridge L. dFOXO-independent effects of reduced insulin-like signaling in Drosophila. Aging Cell. 10: 735-48. PMID 21443682 DOI: 10.1111/j.1474-9726.2011.00707.x |
0.764 |
|
| 2011 |
Bjedov I, Partridge L. A longer and healthier life with TOR down-regulation: genetics and drugs. Biochemical Society Transactions. 39: 460-5. PMID 21428920 DOI: 10.1042/Bst0390460 |
0.755 |
|
| 2011 |
Lee SF, Chen Y, Varan AK, Wee CW, Rako L, Axford JK, Good RT, Blacket MJ, Reuter C, Partridge L, Hoffmann AA. Molecular basis of adaptive shift in body size in Drosophila melanogaster: functional and sequence analyses of the Dca gene. Molecular Biology and Evolution. 28: 2393-402. PMID 21393605 DOI: 10.1093/Molbev/Msr064 |
0.453 |
|
| 2011 |
Selman C, Partridge L, Withers DJ. Replication of extended lifespan phenotype in mice with deletion of insulin receptor substrate 1. Plos One. 6: e16144. PMID 21283571 DOI: 10.1371/journal.pone.0016144 |
0.357 |
|
| 2011 |
Partridge L, Thornton J, Bates G. The new science of ageing. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 366: 6-8. PMID 21115524 DOI: 10.1098/Rstb.2010.0298 |
0.328 |
|
| 2011 |
Alic N, Hoddinott MP, Vinti G, Partridge L. Lifespan extension by increased expression of the Drosophila homologue of the IGFBP7 tumour suppressor. Aging Cell. 10: 137-47. PMID 21108726 DOI: 10.1111/J.1474-9726.2010.00653.X |
0.712 |
|
| 2011 |
Partridge L. Some highlights of research on aging with invertebrates, 2010. Aging Cell. 10: 5-9. PMID 21078113 DOI: 10.1111/j.1474-9726.2010.00649.x |
0.426 |
|
| 2011 |
Partridge L, Alic N, Bjedov I, Piper MD. Ageing in Drosophila: the role of the insulin/Igf and TOR signalling network. Experimental Gerontology. 46: 376-81. PMID 20849947 DOI: 10.1016/J.Exger.2010.09.003 |
0.816 |
|
| 2011 |
Wigby S, Slack C, Grönke S, Martinez P, Calboli FC, Chapman T, Partridge L. Insulin signalling regulates remating in female Drosophila. Proceedings. Biological Sciences / the Royal Society. 278: 424-31. PMID 20739318 DOI: 10.1098/Rspb.2010.1390 |
0.808 |
|
| 2011 |
Kerr F, Augustin H, Piper MD, Gandy C, Allen MJ, Lovestone S, Partridge L. Dietary restriction delays aging, but not neuronal dysfunction, in Drosophila models of Alzheimer's disease. Neurobiology of Aging. 32: 1977-89. PMID 19969390 DOI: 10.1016/J.Neurobiolaging.2009.10.015 |
0.692 |
|
| 2011 |
Ostler EL, Iqbal A, Faragher RG, Naughton D, Piper M, Partridge L. Chemical analysis of aging: testing predictions from green theory F1000research. 2. DOI: 10.7490/F1000Research.1743.1 |
0.7 |
|
| 2010 |
Fontana L, Partridge L, Longo VD. Extending healthy life span--from yeast to humans. Science (New York, N.Y.). 328: 321-6. PMID 20395504 DOI: 10.1126/science.1172539 |
0.394 |
|
| 2010 |
Jacobson J, Lambert AJ, Portero-OtÃn M, Pamplona R, Magwere T, Miwa S, Driege Y, Brand MD, Partridge L. Biomarkers of aging in Drosophila. Aging Cell. 9: 466-77. PMID 20367621 DOI: 10.1111/J.1474-9726.2010.00573.X |
0.344 |
|
| 2010 |
Piper MD, Wong R, Grandison RC, Bass TM, Martinez PM, Partridge L. Water-independent effects of dietary restriction in Drosophila. Proceedings of the National Academy of Sciences of the United States of America. 107: E54-6; author reply . PMID 20363961 DOI: 10.1073/Pnas.0914686107 |
0.667 |
|
| 2010 |
Slack C, Werz C, Wieser D, Alic N, Foley A, Stocker H, Withers DJ, Thornton JM, Hafen E, Partridge L. Regulation of lifespan, metabolism, and stress responses by the Drosophila SH2B protein, Lnk. Plos Genetics. 6: e1000881. PMID 20333234 DOI: 10.1371/Journal.Pgen.1000881 |
0.805 |
|
| 2010 |
Grönke S, Clarke DF, Broughton S, Andrews TD, Partridge L. Molecular evolution and functional characterization of Drosophila insulin-like peptides. Plos Genetics. 6: e1000857. PMID 20195512 DOI: 10.1371/journal.pgen.1000857 |
0.385 |
|
| 2010 |
Broughton SJ, Slack C, Alic N, Metaxakis A, Bass TM, Driege Y, Partridge L. DILP-producing median neurosecretory cells in the Drosophila brain mediate the response of lifespan to nutrition. Aging Cell. 9: 336-46. PMID 20156206 DOI: 10.1111/J.1474-9726.2010.00558.X |
0.8 |
|
| 2010 |
Bjedov I, Toivonen JM, Kerr F, Slack C, Jacobson J, Foley A, Partridge L. Mechanisms of life span extension by rapamycin in the fruit fly Drosophila melanogaster. Cell Metabolism. 11: 35-46. PMID 20074526 DOI: 10.1016/J.Cmet.2009.11.010 |
0.802 |
|
| 2010 |
Partridge L. The new biology of ageing. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 365: 147-54. PMID 20008392 DOI: 10.1098/rstb.2009.0222 |
0.376 |
|
| 2010 |
Partridge L, Harvey PH. The ecological context of life history evolution. Science (New York, N.Y.). 241: 1449-55. PMID 17790040 DOI: 10.1126/science.241.4872.1449 |
0.336 |
|
| 2009 |
Slaidina M, Delanoue R, Gronke S, Partridge L, Léopold P. A Drosophila insulin-like peptide promotes growth during nonfeeding states. Developmental Cell. 17: 874-84. PMID 20059956 DOI: 10.1016/j.devcel.2009.10.009 |
0.357 |
|
| 2009 |
Grandison RC, Piper MD, Partridge L. Amino-acid imbalance explains extension of lifespan by dietary restriction in Drosophila. Nature. 462: 1061-4. PMID 19956092 DOI: 10.1038/Nature08619 |
0.694 |
|
| 2009 |
Selman C, Tullet JM, Wieser D, Irvine E, Lingard SJ, Choudhury AI, Claret M, Al-Qassab H, Carmignac D, Ramadani F, Woods A, Robinson IC, Schuster E, Batterham RL, Kozma SC, ... ... Partridge L, et al. Ribosomal protein S6 kinase 1 signaling regulates mammalian life span. Science (New York, N.Y.). 326: 140-4. PMID 19797661 DOI: 10.1126/Science.1177221 |
0.386 |
|
| 2009 |
Ikeya T, Broughton S, Alic N, Grandison R, Partridge L. The endosymbiont Wolbachia increases insulin/IGF-like signalling in Drosophila. Proceedings. Biological Sciences / the Royal Society. 276: 3799-807. PMID 19692410 DOI: 10.1098/Rspb.2009.0778 |
0.711 |
|
| 2009 |
Iqbal A, Piper M, Faragher RG, Naughton DP, Partridge L, Ostler EL. Chemical changes in aging Drosophila melanogaster. Age (Dordrecht, Netherlands). 31: 343-51. PMID 19585275 DOI: 10.1007/S11357-009-9105-4 |
0.693 |
|
| 2009 |
Wong R, Piper MD, Wertheim B, Partridge L. Quantification of food intake in Drosophila. Plos One. 4: e6063. PMID 19557170 DOI: 10.1371/Journal.Pone.0006063 |
0.658 |
|
| 2009 |
Humphrey DM, Toivonen JM, Giannakou M, Partridge L, Brand MD. Expression of human uncoupling protein-3 in Drosophila insulin-producing cells increases insulin-like peptide (DILP) levels and shortens lifespan. Experimental Gerontology. 44: 316-27. PMID 19385039 DOI: 10.1016/J.Exger.2009.02.001 |
0.31 |
|
| 2009 |
Broughton S, Partridge L. Insulin/IGF-like signalling, the central nervous system and aging. The Biochemical Journal. 418: 1-12. PMID 19159343 DOI: 10.1042/BJ20082102 |
0.391 |
|
| 2009 |
Grandison RC, Wong R, Bass TM, Partridge L, Piper MD. Effect of a standardised dietary restriction protocol on multiple laboratory strains of Drosophila melanogaster. Plos One. 4: e4067. PMID 19119322 DOI: 10.1371/Journal.Pone.0004067 |
0.682 |
|
| 2009 |
Toivonen JM, Partridge L. Endocrine regulation of aging and reproduction in Drosophila. Molecular and Cellular Endocrinology. 299: 39-50. PMID 18682271 DOI: 10.1016/j.mce.2008.07.005 |
0.432 |
|
| 2008 |
Broughton S, Alic N, Slack C, Bass T, Ikeya T, Vinti G, Tommasi AM, Driege Y, Hafen E, Partridge L. Reduction of DILP2 in Drosophila triages a metabolic phenotype from lifespan revealing redundancy and compensation among DILPs. Plos One. 3: e3721. PMID 19005568 DOI: 10.1371/Journal.Pone.0003721 |
0.803 |
|
| 2008 |
Alic N, Partridge L. Stage debut for the elusive Drosophila insulin-like growth factor binding protein. Journal of Biology. 7: 18. PMID 18620552 DOI: 10.1186/Jbiol79 |
0.681 |
|
| 2008 |
Barnes AI, Wigby S, Boone JM, Partridge L, Chapman T. Feeding, fecundity and lifespan in female Drosophila melanogaster. Proceedings. Biological Sciences / the Royal Society. 275: 1675-83. PMID 18430646 DOI: 10.1098/Rspb.2008.0139 |
0.728 |
|
| 2008 |
Partridge L, Brüning JC. Forkhead transcription factors and ageing Oncogene. 27: 2351-2363. PMID 18391977 DOI: 10.1038/onc.2008.28 |
0.394 |
|
| 2008 |
Murphy MP, Partridge L. Toward a control theory analysis of aging. Annual Review of Biochemistry. 77: 777-98. PMID 18318658 DOI: 10.1146/annurev.biochem.77.070606.101605 |
0.354 |
|
| 2008 |
Wong R, Piper MD, Blanc E, Partridge L. Pitfalls of measuring feeding rate in the fruit fly Drosophila melanogaster. Nature Methods. 5: 214-5; author reply . PMID 18309307 DOI: 10.1038/Nmeth0308-214 |
0.651 |
|
| 2008 |
Giannakou ME, Goss M, Partridge L. Role of dFOXO in lifespan extension by dietary restriction in Drosophila melanogaster: not required, but its activity modulates the response. Aging Cell. 7: 187-98. PMID 18241326 DOI: 10.1111/j.1474-9726.2007.00362.x |
0.381 |
|
| 2008 |
Piper MD, Selman C, McElwee JJ, Partridge L. Separating cause from effect: how does insulin/IGF signalling control lifespan in worms, flies and mice? Journal of Internal Medicine. 263: 179-91. PMID 18226095 DOI: 10.1111/J.1365-2796.2007.01906.X |
0.715 |
|
| 2008 |
Selman C, Lingard S, Choudhury AI, Batterham RL, Claret M, Clements M, Ramadani F, Okkenhaug K, Schuster E, Blanc E, Piper MD, Al-Qassab H, Speakman JR, Carmignac D, Robinson IC, ... ... Partridge L, et al. Evidence for lifespan extension and delayed age-related biomarkers in insulin receptor substrate 1 null mice. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 807-18. PMID 17928362 DOI: 10.1096/Fj.07-9261Com |
0.71 |
|
| 2008 |
Butler RN, Miller RA, Perry D, Carnes BA, Williams TF, Cassel C, Brody J, Bernard MA, Partridge L, Kirkwood T, Martin GM, Olshansky SJ. Turn back time Bmj. 337: 810352. DOI: 10.1136/Sbmj.0810352 |
0.307 |
|
| 2007 |
Pletcher SD, Kabil H, Partridge L. Chemical Complexity and the Genetics of Aging. Annual Review of Ecology, Evolution, and Systematics. 38: 299-326. PMID 25685107 DOI: 10.1146/annurev.ecolsys.38.091206.095634 |
0.603 |
|
| 2007 |
Partridge L, Gems D. Benchmarks for ageing studies. Nature. 450: 165-7. PMID 17994065 DOI: 10.1038/450165a |
0.352 |
|
| 2007 |
Bass TM, Grandison RC, Wong R, Martinez P, Partridge L, Piper MD. Optimization of dietary restriction protocols in Drosophila. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 62: 1071-81. PMID 17921418 DOI: 10.1093/Gerona/62.10.1071 |
0.674 |
|
| 2007 |
Bass TM, Weinkove D, Houthoofd K, Gems D, Partridge L. Effects of resveratrol on lifespan in Drosophila melanogaster and Caenorhabditis elegans. Mechanisms of Ageing and Development. 128: 546-52. PMID 17875315 DOI: 10.1016/j.mad.2007.07.007 |
0.342 |
|
| 2007 |
Alic N, Partridge L. Antagonizing Methuselah to extend life span. Genome Biology. 8: 222. PMID 17764591 DOI: 10.1186/Gb-2007-8-8-222 |
0.675 |
|
| 2007 |
McElwee JJ, Schuster E, Blanc E, Piper MD, Thomas JH, Patel DS, Selman C, Withers DJ, Thornton JM, Partridge L, Gems D. Evolutionary conservation of regulated longevity assurance mechanisms. Genome Biology. 8: R132. PMID 17612391 DOI: 10.1186/Gb-2007-8-7-R132 |
0.709 |
|
| 2007 |
Kennington WJ, Hoffmann AA, Partridge L. Mapping regions within cosmopolitan inversion In(3R)Payne associated with natural variation in body size in Drosophila melanogaster. Genetics. 177: 549-56. PMID 17603103 DOI: 10.1534/Genetics.107.074336 |
0.423 |
|
| 2007 |
Toivonen JM, Walker GA, Martinez-Diaz P, Bjedov I, Driege Y, Jacobs HT, Gems D, Partridge L. No influence of Indy on lifespan in Drosophila after correction for genetic and cytoplasmic background effects. Plos Genetics. 3: e95. PMID 17571923 DOI: 10.1371/Journal.Pgen.0030095 |
0.725 |
|
| 2007 |
Giannakou ME, Goss M, Jacobson J, Vinti G, Leevers SJ, Partridge L. Dynamics of the action of dFOXO on adult mortality in Drosophila Aging Cell. 6: 429-438. PMID 17465980 DOI: 10.1111/j.1474-9726.2007.00290.x |
0.386 |
|
| 2007 |
Piper MD, Partridge L. Dietary restriction in Drosophila: delayed aging or experimental artefact? Plos Genetics. 3: e57. PMID 17465680 DOI: 10.1371/Journal.Pgen.0030057 |
0.684 |
|
| 2007 |
Giannakou ME, Partridge L. Role of insulin-like signalling in Drosophila lifespan Trends in Biochemical Sciences. 32: 180-188. PMID 17412594 DOI: 10.1016/j.tibs.2007.02.007 |
0.382 |
|
| 2007 |
Piper M, Mair W, Partridge L. Comment by Matthew Piper, William Mair, Linda Partridge on Min, K.J., Flatt, T., Kulaots, I., Tatar, M. (2006) "Counting calories in Drosophila dietary restriction" Exp. Gerontology, doi:10.1016/j.exger.2006.10.009 Experimental Gerontology. 42: 253-255. PMID 17317064 DOI: 10.1016/J.Exger.2007.01.002 |
0.625 |
|
| 2007 |
Barnes AI, Boone JM, Partridge L, Chapman T. A functioning ovary is not required for sex peptide to reduce receptivity to mating in D. melanogaster. Journal of Insect Physiology. 53: 343-8. PMID 17303161 DOI: 10.1016/J.Jinsphys.2006.12.008 |
0.527 |
|
| 2007 |
Kabil H, Partridge L, Harshman LG. Superoxide dismutase activities in long-lived Drosophila melanogaster females: Chico1 genotypes and dietary dilution Biogerontology. 8: 201-208. PMID 17103233 DOI: 10.1007/s10522-006-9065-3 |
0.317 |
|
| 2007 |
Toivonen JM, Walker GA, Martinez-Diaz P, Bjedov I, Driege Y, Jacobs HT, Gems D, Partridge L. No influence of Indy on lifespan in Drosophila after correction for genetic and cytoplasmic background effects Plos Genetics. 3: 0973-0983. DOI: 10.1371/journal.pgen.0030095 |
0.685 |
|
| 2007 |
Partridge L. A singular view of ageing Nature. 447: 262-263. DOI: 10.1038/447262A |
0.319 |
|
| 2007 |
Wertheim B, Milton C, Hoffmann A, Godfray C, Partridge L. Functional genomics of plastic and evolutionary responses to thermal stress Comparative Biochemistry and Physiology Part a: Molecular & Integrative Physiology. 146: S206. DOI: 10.1016/J.Cbpa.2007.01.459 |
0.388 |
|
| 2007 |
Partridge L. Insulin signalling, oxidative stress and aging Comparative Biochemistry and Physiology Part a: Molecular & Integrative Physiology. 146: S59-S60. DOI: 10.1016/j.cbpa.2007.01.052 |
0.321 |
|
| 2006 |
Selman C, Kerrison ND, Cooray A, Piper MD, Lingard SJ, Barton RH, Schuster EF, Blanc E, Gems D, Nicholson JK, Thornton JM, Partridge L, Withers DJ. Coordinated multitissue transcriptional and plasma metabonomic profiles following acute caloric restriction in mice. Physiological Genomics. 27: 187-200. PMID 16882887 DOI: 10.1152/Physiolgenomics.00084.2006 |
0.664 |
|
| 2006 |
Partridge L, Gems D. Beyond the evolutionary theory of ageing, from functional genomics to evo-gero Trends in Ecology and Evolution. 21: 334-340. PMID 16769434 DOI: 10.1016/j.tree.2006.02.008 |
0.351 |
|
| 2006 |
Barnes AI, Boone JM, Jacobson J, Partridge L, Chapman T. No extension of lifespan by ablation of germ line in Drosophila. Proceedings. Biological Sciences / the Royal Society. 273: 939-47. PMID 16627279 DOI: 10.1098/Rspb.2005.3388 |
0.545 |
|
| 2006 |
Kennington WJ, Partridge L, Hoffmann AA. Patterns of diversity and linkage disequilibrium within the cosmopolitan inversion In(3R)Payne in Drosophila melanogaster are indicative of coadaptation. Genetics. 172: 1655-63. PMID 16322502 DOI: 10.1534/Genetics.105.053173 |
0.416 |
|
| 2005 |
Wertheim B, Kraaijeveld AR, Schuster E, Blanc E, Hopkins M, Pletcher SD, Strand MR, Partridge L, Godfray HC. Genome-wide gene expression in response to parasitoid attack in Drosophila. Genome Biology. 6: R94. PMID 16277749 DOI: 10.1186/Gb-2005-6-11-R94 |
0.568 |
|
| 2005 |
Warner H, Anderson J, Austad S, Bergamini E, Bredesen D, Butler R, Carnes BA, Clark BF, Cristofalo V, Faulkner J, Guarente L, Harrison DE, Kirkwood T, Lithgow G, Martin G, ... ... Partridge L, et al. Science fact and the SENS agenda. What can we reasonably expect from ageing research? Embo Reports. 6: 1006-8. PMID 16264422 DOI: 10.1038/Sj.Embor.7400555 |
0.329 |
|
| 2005 |
Piper MDW, Skorupa D, Partridge L. Diet, metabolism and lifespan in Drosophila Experimental Gerontology. 40: 857-862. PMID 16137851 DOI: 10.1016/J.Exger.2005.06.013 |
0.349 |
|
| 2005 |
Mair W, Piper MD, Partridge L. Calories do not explain extension of life span by dietary restriction in Drosophila. Plos Biology. 3: e223. PMID 16000018 DOI: 10.1371/Journal.Pbio.0030223 |
0.68 |
|
| 2005 |
Piper MDW, Mair W, Partridge L. Counting the calories: The role of specific nutrients in extension of life span by food restriction Journals of Gerontology - Series a Biological Sciences and Medical Sciences. 60: 549-555. PMID 15972601 DOI: 10.1093/Gerona/60.5.549 |
0.312 |
|
| 2005 |
Partridge L, Piper MD, Mair W. Dietary restriction in Drosophila. Mechanisms of Ageing and Development. 126: 938-50. PMID 15935441 DOI: 10.1016/J.Mad.2005.03.023 |
0.702 |
|
| 2005 |
Richard DS, Rybczynski R, Wilson TG, Wang Y, Wayne ML, Zhou Y, Partridge L, Harshman LG. Insulin signaling is necessary for vitellogenesis in Drosophila melanogaster independent of the roles of juvenile hormone and ecdysteroids: female sterility of the chico1 insulin signaling mutation is autonomous to the ovary. Journal of Insect Physiology. 51: 455-64. PMID 15890189 DOI: 10.1016/J.Jinsphys.2004.12.013 |
0.352 |
|
| 2005 |
Partridge L, Gems D, Withers DJ. Sex and death: What is the connection? Cell. 120: 461-472. PMID 15734679 DOI: 10.1016/j.cell.2005.01.026 |
0.369 |
|
| 2005 |
Broughton SJ, Piper MD, Ikeya T, Bass TM, Jacobson J, Driege Y, Martinez P, Hafen E, Withers DJ, Leevers SJ, Partridge L. Longer lifespan, altered metabolism, and stress resistance in Drosophila from ablation of cells making insulin-like ligands. Proceedings of the National Academy of Sciences of the United States of America. 102: 3105-10. PMID 15708981 DOI: 10.1073/Pnas.0405775102 |
0.689 |
|
| 2005 |
Partridge L, Pletcher SD, Mair W. Dietary restriction, mortality trajectories, risk and damage. Mechanisms of Ageing and Development. 126: 35-41. PMID 15610760 DOI: 10.1016/j.mad.2004.09.017 |
0.582 |
|
| 2005 |
Partridge L, Brand MD. Special issue on dietary restriction: Dietary restriction, longevity and ageing - The current state of our knowledge and ignorance Mechanisms of Ageing and Development. 126: 911-912. DOI: 10.1016/J.Mad.2005.04.003 |
0.3 |
|
| 2005 |
Piper MDW, Selman C, McElwee JJ, Partridge L. Models of insulin signalling and longevity Drug Discovery Today: Disease Models. 2: 249-256. DOI: 10.1016/J.Ddmod.2005.11.001 |
0.378 |
|
| 2004 |
Giannakou ME, Partridge L. The interaction between FOXO and SIRT1: Tipping the balance towards survival Trends in Cell Biology. 14: 408-412. PMID 15308206 DOI: 10.1016/j.tcb.2004.07.006 |
0.31 |
|
| 2004 |
Hulbert AJ, Clancy DJ, Mair W, Braeckman BP, Gems D, Partridge L. Metabolic rate is not reduced by dietary-restriction or by lowered insulin/IGF-1 signalling and is not correlated with individual lifespan in Drosophila melanogaster. Experimental Gerontology. 39: 1137-43. PMID 15288688 DOI: 10.1016/J.Exger.2004.04.006 |
0.693 |
|
| 2004 |
Mair W, Sgrò CM, Johnson AP, Chapman T, Partridge L. Lifespan extension by dietary restriction in female Drosophila melanogaster is not caused by a reduction in vitellogenesis or ovarian activity. Experimental Gerontology. 39: 1011-9. PMID 15236760 DOI: 10.1016/J.Exger.2004.03.018 |
0.567 |
|
| 2004 |
Giannakou ME, Goss M, Jünger MA, Hafen E, Leevers SJ, Partridge L. Long-lived Drosophila with overexpressed dFOXO in adult fat body. Science (New York, N.Y.). 305: 361. PMID 15192154 DOI: 10.1126/Science.1098219 |
0.395 |
|
| 2004 |
Magwere T, Chapman T, Partridge L. Sex differences in the effect of dietary restriction on life span and mortality rates in female and male Drosophila melanogaster. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 59: 3-9. PMID 14718480 DOI: 10.1093/Gerona/59.1.B3 |
0.564 |
|
| 2004 |
Rauser CL, Mueller LD, Rose MR, Mair W, Goymer P, Pletcher SD, Partridge L. Dietary Restriction in Drosophilla [2] (multiple letters) Science. 303: 1610-1612. |
0.496 |
|
| 2003 |
Hoffmann AA, Scott M, Partridge L, Hallas R. Overwintering in Drosophila melanogaster: Outdoor field cage experiments on clinal and laboratory selected populations help to elucidate traits under selection Journal of Evolutionary Biology. 16: 614-623. PMID 14632225 DOI: 10.1046/J.1420-9101.2003.00561.X |
0.436 |
|
| 2003 |
Mair W, Goymer P, Pletcher SD, Partridge L. Demography of dietary restriction and death in Drosophila. Science (New York, N.Y.). 301: 1731-3. PMID 14500985 DOI: 10.1126/science.1086016 |
0.61 |
|
| 2003 |
Chapman T, Bangham J, Vinti G, Seifried B, Lung O, Wolfner MF, Smith HK, Partridge L. The sex peptide of Drosophila melanogaster: female post-mating responses analyzed by using RNA interference. Proceedings of the National Academy of Sciences of the United States of America. 100: 9923-8. PMID 12893873 DOI: 10.1073/Pnas.1631635100 |
0.519 |
|
| 2003 |
Bangham J, Chapman T, Smith HK, Partridge L. Influence of female reproductive anatomy on the outcome of sperm competition in Drosophila melanogaster. Proceedings. Biological Sciences / the Royal Society. 270: 523-30. PMID 12641908 DOI: 10.1098/Rspb.2002.2237 |
0.514 |
|
| 2002 |
Gems D, Pletcher S, Partridge L. Interpreting interactions between treatments that slow aging Aging Cell. 1: 1-9. PMID 12882347 DOI: 10.1046/J.1474-9728.2002.00003.X |
0.607 |
|
| 2002 |
Carey JR, Liedo P, Harshman L, Zhang Y, Müller HG, Partridge L, Wang JL. Life history response of Mediterranean fruit flies to dietary restriction. Aging Cell. 1: 140-8. PMID 12882344 DOI: 10.1046/J.1474-9728.2002.00019.X |
0.353 |
|
| 2002 |
Partridge L, Gems D. The evolution of longevity Current Biology : Cb. 12: R544-546. PMID 12194832 DOI: 10.1016/S0960-9822(02)01048-5 |
0.428 |
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| 2002 |
Pletcher SD, Macdonald SJ, Marguerie R, Certa U, Stearns SC, Goldstein DB, Partridge L. Genome-wide transcript profiles in aging and calorically restricted Drosophila melanogaster. Current Biology : Cb. 12: 712-23. PMID 12007414 DOI: 10.1016/S0960-9822(02)00808-4 |
0.624 |
|
| 2002 |
Partridge L, Gems D. Mechanisms of ageing: Public or private? Nature Reviews Genetics. 3: 165-175. PMID 11972154 DOI: 10.1038/nrg753 |
0.372 |
|
| 2002 |
Clancy DJ, Gems D, Hafen E, Leevers SJ, Partridge L. Dietary restriction in long-lived dwarf flies. Science (New York, N.Y.). 296: 319. PMID 11951037 DOI: 10.1126/Science.1069366 |
0.687 |
|
| 2002 |
Carey JR, Liedo P, Harshman L, Zhang Y, Müller HG, Partridge L, Wang JL. A mortality cost of virginity at older ages in female Mediterranean fruit flies. Experimental Gerontology. 37: 507-12. PMID 11830353 DOI: 10.1016/S0531-5565(01)00230-3 |
0.327 |
|
| 2002 |
Carey JR, Liedo P, Harshman L, Liu X, Müller HG, Partridge L, Wang JL. Food pulses increase longevity and induce cyclical egg production in Mediterranean fruit flies Functional Ecology. 16: 313-325. DOI: 10.1046/J.1365-2435.2002.00633.X |
0.306 |
|
| 2002 |
Bangham J, Chapman T, Partridge L. Effects of body size, accessory gland and testis size on pre- and postcopulatory success in Drosophila melanogaster Animal Behaviour. 64: 915-921. DOI: 10.1006/Anbe.2002.1976 |
0.517 |
|
| 2001 |
Partridge L. The Insulin Signaling Pathway and Aging in Drosophila. Thescientificworldjournal. 1: 76. PMID 30147550 DOI: 10.1100/tsw.2001.138 |
0.359 |
|
| 2001 |
Sgrò CM, Partridge L. Laboratory adaptation of life history in Drosophila. The American Naturalist. 158: 657-8. PMID 18707359 DOI: 10.1086/323592 |
0.543 |
|
| 2001 |
Chapman T, Herndon LA, Heifetz Y, Partridge L, Wolfner MF. The Acp26Aa seminal fluid protein is a modulator of early egg hatchability in Drosophila melanogaster. Proceedings. Biological Sciences / the Royal Society. 268: 1647-54. PMID 11506676 DOI: 10.1098/Rspb.2001.1684 |
0.527 |
|
| 2001 |
Gems D, Partridge L. Insulin/IGF signalling and ageing: seeing the bigger picture. Current Opinion in Genetics & Development. 11: 287-92. PMID 11377965 DOI: 10.1016/S0959-437X(00)00192-1 |
0.397 |
|
| 2001 |
Hoffmann AA, Hallas R, Sinclair C, Partridge L. Rapid loss of stress resistance in drosophila melanogaster under adaptation to laboratory culture Evolution. 55: 436-438. PMID 11308098 DOI: 10.1111/J.0014-3820.2001.Tb01305.X |
0.424 |
|
| 2001 |
Partridge L. Evolutionary theories of ageing applied to long-lived organisms. Experimental Gerontology. 36: 641-50. PMID 11295505 DOI: 10.1016/S0531-5565(00)00232-1 |
0.374 |
|
| 2001 |
Clancy DJ, Gems D, Harshman LG, Oldham S, Stocker H, Hafen E, Leevers SJ, Partridge L. Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein. Science (New York, N.Y.). 292: 104-6. PMID 11292874 DOI: 10.1126/Science.1057991 |
0.703 |
|
| 2001 |
Hoffmann AA, Hallas R, Sinclair C, Partridge L. RAPID LOSS OF STRESS RESISTANCE IN DROSOPHILA MELANOGASTER UNDER ADAPTATION TO LABORATORY CULTURE Evolution. 55: 436. DOI: 10.1554/0014-3820(2001)055[0436:RLOSRI]2.0.CO;2 |
0.311 |
|
| 2000 |
Sgrò CM, Geddes G, Fowler K, Partridge L. Selection on age at reproduction in Drosophila melanogaster: female mating frequency as a correlated response. Evolution; International Journal of Organic Evolution. 54: 2152-5. PMID 11209790 DOI: 10.1111/J.0014-3820.2000.Tb01257.X |
0.594 |
|
| 2000 |
Chapman T, Neubaum DM, Wolfner MF, Partridge L. The role of male accessory gland protein Acp36DE in sperm competition in Drosophila melanogaster. Proceedings. Biological Sciences / the Royal Society. 267: 1097-105. PMID 10885514 DOI: 10.1098/Rspb.2000.1114 |
0.512 |
|
| 2000 |
Sgro CM, Partridge L. Evolutionary responses of the life history of wild-caught Drosophila melanogaster to two standard methods of laboratory culture American Naturalist. 156: 341-353. DOI: 10.1086/303394 |
0.543 |
|
| 1999 |
Miyatake T, Chapman T, Partridge L. Mating-induced inhibition of remating in female Mediterranean fruit flies Ceratitis capitata. Journal of Insect Physiology. 45: 1021-1028. PMID 12770277 DOI: 10.1016/S0022-1910(99)00083-9 |
0.511 |
|
| 1999 |
Sgrò CM, Partridge L. A delayed wave of death from reproduction in Drosophila. Science (New York, N.Y.). 286: 2521-4. PMID 10617470 DOI: 10.1126/Science.286.5449.2521 |
0.576 |
|
| 1999 |
Partridge L, Mangel M. Messages from mortality: the evolution of death rates in the old. Trends in Ecology & Evolution. 14: 438-442. PMID 10511720 DOI: 10.1016/S0169-5347(99)01646-8 |
0.304 |
|
| 1999 |
Partridge L, Prowse N, Pignatelli P. Another set of responses and correlated responses to selection on age at reproduction in Drosophila melanogaster. Proceedings. Biological Sciences. 266: 255-61. PMID 10081162 DOI: 10.1098/rspb.1999.0630 |
0.346 |
|
| 1998 |
Sgrò CM, Chapman T, Partridge L. Sex-specific selection on time to remate in Drosophila melanogaster. Animal Behaviour. 56: 1267-1278. PMID 9819344 DOI: 10.1006/Anbe.1998.0900 |
0.648 |
|
| 1998 |
Chapman T, Miyatake T, Smith HK, Partridge L. Interactions of mating, egg production and death rates in females of the Mediterranean fruit fly, Ceratitis capitata. Proceedings. Biological Sciences / the Royal Society. 265: 1879-94. PMID 9802244 DOI: 10.1098/Rspb.1998.0516 |
0.516 |
|
| 1998 |
Rogina B, Vaupel JW, Partridge L, Helfand SL. Regulation of gene expression is preserved in aging Drosophila melanogaster. Current Biology : Cb. 8: 475-8. PMID 9550706 DOI: 10.1016/S0960-9822(98)70184-8 |
0.352 |
|
| 1998 |
Parker GA, Partridge L. Sexual conflict and speciation. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 353: 261-74. PMID 9533125 DOI: 10.1098/rstb.1998.0208 |
0.309 |
|
| 1998 |
Partridge L, Sgrò CM. Behavioural genetics: molecular genetics meets feeding ecology. Current Biology : Cb. 8: R23-4. PMID 9427617 DOI: 10.1016/S0960-9822(98)70011-9 |
0.535 |
|
| 1997 |
McCabe J, Partridge L. AN INTERACTION BETWEEN ENVIRONMENTAL TEMPERATURE AND GENETIC VARIATION FOR BODY SIZE FOR THE FITNESS OF ADULT FEMALE DROSOPHILA MELANOGASTER. Evolution; International Journal of Organic Evolution. 51: 1164-1174. PMID 28565476 DOI: 10.1111/j.1558-5646.1997.tb03964.x |
0.306 |
|
| 1997 |
Azevedo RBR, French V, Partridge L. Life-History Consequences Of Egg Size In Drosophila Melanogaster The American Naturalist. 150: 250-282. PMID 18811284 DOI: 10.1086/286065 |
0.301 |
|
| 1997 |
Wolfner MF, Partridge L, Lewin S, Kalb JM, Chapman T, Herndon LA. Mating and hormonal triggers regulate accessory gland gene expression in male Drosophila. Journal of Insect Physiology. 43: 1117-1123. PMID 12770484 DOI: 10.1016/S0022-1910(97)00062-0 |
0.521 |
|
| 1997 |
Charlesworth B, Partridge L. Ageing: levelling of the grim reaper. Current Biology : Cb. 7: R440-2. PMID 9210361 DOI: 10.1016/S0960-9822(06)00213-2 |
0.33 |
|
| 1996 |
Chapman T, Partridge L. Female fitness in Drosophila melanogaster: an interaction between the effect of nutrition and of encounter rate with males. Proceedings. Biological Sciences / the Royal Society. 263: 755-9. PMID 8763795 DOI: 10.1098/Rspb.1996.0113 |
0.537 |
|
| 1996 |
Chapman T, Partridge L. Sexual conflict as fuel for evolution. Nature. 381: 189-90. PMID 8622753 DOI: 10.1038/381189A0 |
0.491 |
|
| 1996 |
Partridge L, Barton NH. On measuring the rate of ageing Proceedings of the Royal Society B: Biological Sciences. 263: 1365-1371. DOI: 10.1098/Rspb.1996.0200 |
0.361 |
|
| 1996 |
Chapman T, Choffat Y, Lucas WE, Kubli E, Partridge L. Lack of response to sex-peptide results in increased cost of mating in dunce Drosophila melanogaster females Journal of Insect Physiology. 42: 1007-1015. DOI: 10.1016/S0022-1910(96)00070-4 |
0.518 |
|
| 1996 |
CORDTS R, PARTRIDGE L. Courtship reduces longevity of maleDrosophila melanogaster Animal Behaviour. 52: 269-278. DOI: 10.1006/anbe.1996.0172 |
0.308 |
|
| 1995 |
Chapman T, Liddle LF, Kalb JM, Wolfner MF, Partridge L. Cost of mating in Drosophila melanogaster females is mediated by male accessory gland products. Nature. 373: 241-4. PMID 7816137 DOI: 10.1038/373241A0 |
0.519 |
|
| 1994 |
Partridge L, Prowse N. Gerontology. Mutation, variation and the evolution of ageing. Current Biology : Cb. 4: 430-2. PMID 7922358 DOI: 10.1016/S0960-9822(00)00094-4 |
0.325 |
|
| 1994 |
Chapman T, Trevitt S, Partridge L. Remating and male-derived nutrients in Drosophila melanogaster Journal of Evolutionary Biology. 7: 51-69. DOI: 10.1046/J.1420-9101.1994.7010051.X |
0.527 |
|
| 1993 |
Partridge L, Barton NH. Optimality, mutation and the evolution of ageing. Nature. 362: 305-11. PMID 8455716 DOI: 10.1038/362305A0 |
0.306 |
|
| 1993 |
Chapman T, Hutchings J, Partridge L. No reduction in the cost of mating for Drosophila melanogaster females mating with spermless males. Proceedings. Biological Sciences / the Royal Society. 253: 211-7. PMID 8234360 DOI: 10.1098/rspb.1993.0105 |
0.502 |
|
| 1993 |
Partridge L, Barton NH. Evolution of aging: testing the theory using Drosophila. Genetica. 91: 89-98. PMID 8125281 DOI: 10.1007/Bf01435990 |
0.33 |
|
| 1993 |
Partridge L. Aging, Sex and DNA Repair . By Carol Bernstein and Harni Bernstein . Academic Press. 1991. 382 pages. Price $44. ISBN 0 12 092840 4. - Genetic Effects on Aging II . Edited by D. E. Harrison. CRC Press. 1990. 573 pages. Price £50. ISBN 0 936923 318. Genetics Research. 62: 79-81. DOI: 10.1017/S0016672300031591 |
0.316 |
|
| 1992 |
Partridge L, Fowler K. DIRECT AND CORRELATED RESPONSES TO SELECTION ON AGE AT REPRODUCTION IN DROSOPHILA MELANOGASTER. Evolution; International Journal of Organic Evolution. 46: 76-91. PMID 28564973 DOI: 10.1111/J.1558-5646.1992.Tb01986.X |
0.318 |
|
| 1991 |
Partridge L, Sibly R. Constraints in the Evolution of Life Histories Philosophical Transactions of the Royal Society B. 332: 3-13. DOI: 10.1098/Rstb.1991.0027 |
0.324 |
|
| 1991 |
Trevitt S, Partridge L. A cost of receiving sperm in the female fruitfly Drosophila melanogaster Journal of Insect Physiology. 37: 471-475. DOI: 10.1016/0022-1910(91)90057-7 |
0.301 |
|
| 1989 |
Partridge L. The rare-male effect: what is its evolutionary significance? Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 319: 525-39. PMID 2905490 DOI: 10.1098/RSTB.1988.0063 |
0.315 |
|
| 1989 |
Fowler K, Partridge L. A cost of mating in female fruitflies Nature. 338: 760-761. DOI: 10.1038/338760A0 |
0.333 |
|
| 1988 |
Steele RH, Partridge L. A courtship advantage for small males in Drosophila subobscura Animal Behaviour. 36: 1190-1197. DOI: 10.1016/S0003-3472(88)80078-2 |
0.303 |
|
| 1987 |
Partridge L. Is accelerated senescence a cost of reproduction Functional Ecology. 1: 317-320. DOI: 10.2307/2389786 |
0.378 |
|
| 1987 |
Partridge L, Hoffmann A, Jones J. Male size and mating success in Drosophila melanogaster and D. pseudoobscura under field conditions Animal Behaviour. 35: 468-476. DOI: 10.1016/S0003-3472(87)80272-5 |
0.451 |
|
| 1987 |
Partridge L, Green A, Fowler K. Effects of egg-production and of exposure to males on female survival in Drosophila melanogaster Journal of Insect Physiology. 33: 745-749. DOI: 10.1016/0022-1910(87)90060-6 |
0.309 |
|
| 1986 |
Fowler K, Partridge L. Variation in male fertility explains an apparent effect of genotypic diversity on success in larval competition in Drosophila melanogaster Heredity. 57: 31-36. DOI: 10.1038/Hdy.1986.83 |
0.313 |
|
| 1986 |
Partridge L, Fowler K, Trevitt S, Sharp W. An examination of the effects of males on the survival and egg-production rates of female Drosophila melanogaster Journal of Insect Physiology. 32: 925-929. DOI: 10.1016/0022-1910(86)90140-X |
0.311 |
|
| 1985 |
Partridge L, Andrews R. The effect of reproductive activity on the longevity of male Drosophila melanogaster is not caused by an acceleration of ageing Journal of Insect Physiology. 31: 393-395. DOI: 10.1016/0022-1910(85)90084-8 |
0.365 |
|
| 1983 |
Partridge L, Farquhar M. Lifetime mating success of male fruitflies (Drosophila melanogaster) is related to their size Animal Behaviour. 31: 871-877. DOI: 10.1016/S0003-3472(83)80242-5 |
0.311 |
|
| 1981 |
PARTRIDGE L. Does mate choice occur in Drosophila melanogaster? (reply) Nature. 293: 492-492. DOI: 10.1038/293492B0 |
0.307 |
|
| 1980 |
Partridge L. Mate choice increases a component of offspring fitness in fruit flies Nature. 283: 290-291. DOI: 10.1038/283290A0 |
0.314 |
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