Stafford Lightman - Publications

Affiliations: 
University of Bristol, Bristol, England, United Kingdom 
Area:
HPA axis, stress-related behaviour

46/500 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Lightman S, Upton T. How an appreciation of dynamics has altered our understanding of the HPA axis. Stress (Amsterdam, Netherlands). 27: 2297371. PMID 38258508 DOI: 10.1080/10253890.2023.2297371  0.721
2023 Russell G, Kalafatakis K, Durant C, Marchant N, Thakrar J, Thirard R, King J, Bowles J, Upton T, Thai NJ, Brooks JCW, Wilson A, Phillips K, Ferguson S, Grabski M, ... ... Lightman SL, et al. Ultradian hydrocortisone replacement alters neuronal processing, emotional ambiguity, affect and fatigue in adrenal insufficiency: The PULSES trial. Journal of Internal Medicine. PMID 37857352 DOI: 10.1111/joim.13721  0.699
2023 Upton TJ, Zavala E, Methlie P, Kämpe O, Tsagarakis S, Øksnes M, Bensing S, Vassiliadi DA, Grytaas MA, Botusan IR, Ueland G, Berinder K, Simunkova K, Balomenaki M, Margaritopoulos D, ... ... Lightman SL, et al. High-resolution daily profiles of tissue adrenal steroids by portable automated collection. Science Translational Medicine. 15: eadg8464. PMID 37343084 DOI: 10.1126/scitranslmed.adg8464  0.709
2022 Galvis D, Zavala E, Walker JJ, Upton T, Lightman SL, Angelini GD, Evans J, Rogers CA, Phillips K, Gibbison B. Modelling the dynamic interaction of systemic inflammation and the hypothalamic-pituitary-adrenal (HPA) axis during and after cardiac surgery. Journal of the Royal Society, Interface. 19: 20210925. PMID 35472267 DOI: 10.1098/rsif.2021.0925  0.724
2020 Fudulu DP, Angelini GD, Papadopoulou FF, Evans J, Walker-Smith T, Kema I, Van Fassen M, Stoica S, Caputo M, Lightman S, Gibbison B. The Peacock study: feasibility of the dynamic characterisation of the paediatric hypothalamic-pituitary-adrenal function during and after cardiac surgery. Bmc Cardiovascular Disorders. 20: 245. PMID 32450805 DOI: 10.1186/S12872-020-01516-Y  0.34
2019 Russell G, Lightman S. The human stress response. Nature Reviews. Endocrinology. PMID 31249398 DOI: 10.1038/S41574-019-0228-0  0.402
2019 Choudhury S, Lightman S, Meeran K. Improving glucocorticoid replacement profiles in adrenal insufficiency. Clinical Endocrinology. PMID 31017681 DOI: 10.1111/Cen.13999  0.314
2018 Fudulu D, Lightman S, Caputo M, Angelini G. Steroids in paediatric heart surgery: eminence or evidence-based practice? Indian Journal of Thoracic and Cardiovascular Surgery : Official Organ, Association of Thoracic and Cardiovascular Surgeons of India. 34: 483-487. PMID 33060920 DOI: 10.1007/S12055-018-0670-Y  0.308
2018 Fudulu DP, Gibbison B, Upton T, Stoica SC, Caputo M, Lightman S, Angelini GD. Corticosteroids in Pediatric Heart Surgery: Myth or Reality. Frontiers in Pediatrics. 6: 112. PMID 29732365 DOI: 10.3389/Fped.2018.00112  0.706
2016 Oster H, Challet E, Ott V, Arvat E, de Kloet ER, Dijk DJ, Lightman S, Vgontzas A, Van Cauter E. The functional and clinical significance of the 24-h rhythm of circulating glucocorticoids. Endocrine Reviews. er20151080. PMID 27749086 DOI: 10.1210/Er.2015-1080  0.644
2016 Henley D, Lightman S, Carrell R. Cortisol and CBG - Getting cortisol to the right place at the right time. Pharmacology & Therapeutics. PMID 27411675 DOI: 10.1016/J.Pharmthera.2016.06.020  0.305
2016 Stirrat L, Walker J, Norman J, Lightman S, Walker B, Reynolds R. Role of cortisol ultradian pulsatility in human pregnancy: a case-control study The Lancet. 387: S93. DOI: 10.1016/S0140-6736(16)00480-3  0.3
2014 Lightman S, Terry JR. The importance of dynamic signalling for endocrine regulation and drug development: relevance for glucocorticoid hormones. The Lancet. Diabetes & Endocrinology. 2: 593-9. PMID 24731665 DOI: 10.1016/S2213-8587(13)70182-7  0.336
2014 Gibbison B, Walker J, Russell G, Stevenson K, Kershaw Y, Asimakopoulos G, Angelini G, Lightman S. Cardiac surgery alters the sensitivity of the dynamic interaction between the pituitary and adrenal glands Critical Care. 18: 435. DOI: 10.1186/Cc13625  0.342
2012 Vedhara K, Metcalfe C, Brant H, Crown A, Northstone K, Dawe K, Lightman S, Smith GD. Maternal mood and neuroendocrine programming: effects of time of exposure and sex. Journal of Neuroendocrinology. 24: 999-1011. PMID 22385021 DOI: 10.1111/j.1365-2826.2012.02309.x  0.328
2012 Sarabdjitsingh RA, Conway-Campbell BL, Leggett JD, Waite EJ, Meijer OC, De Kloet ER, Lightman SL. Stress responsiveness varies over the ultradian glucocorticoid cycle in a brain-region-specific manner (Endocrinology (2010) 151 (5369-5379) DOI: 10.1210/en.2010-0832) Endocrinology. 153: 6159. DOI: 10.1210/en.2012-1997  0.739
2011 O'Keane V, Lightman S, Patrick K, Marsh M, Papadopoulos AS, Pawlby S, Seneviratne G, Taylor A, Moore R. Changes in the maternal hypothalamic-pituitary-adrenal axis during the early puerperium may be related to the postpartum 'blues'. Journal of Neuroendocrinology. 23: 1149-55. PMID 22004568 DOI: 10.1111/J.1365-2826.2011.02139.X  0.319
2011 O'Keane V, Lightman S, Marsh M, Pawlby S, Papadopoulos AS, Taylor A, Moore R, Patrick K. Increased pituitary-adrenal activation and shortened gestation in a sample of depressed pregnant women: a pilot study. Journal of Affective Disorders. 130: 300-5. PMID 21093926 DOI: 10.1016/J.Jad.2010.10.004  0.303
2010 Walker JJ, Terry JR, Tsaneva-Atanasova K, Armstrong SP, McArdle CA, Lightman SL. Encoding and decoding mechanisms of pulsatile hormone secretion. Journal of Neuroendocrinology. 22: 1226-38. PMID 21054582 DOI: 10.1111/J.1365-2826.2010.02087.X  0.363
2010 Sarabdjitsingh RA, Conway-Campbell BL, Leggett JD, Waite EJ, Meijer OC, de Kloet ER, Lightman SL. Stress responsiveness varies over the ultradian glucocorticoid cycle in a brain-region-specific manner. Endocrinology. 151: 5369-79. PMID 20861228 DOI: 10.1210/En.2010-0832  0.764
2010 Conway-Campbell BL, Sarabdjitsingh RA, McKenna MA, Pooley JR, Kershaw YM, Meijer OC, De Kloet ER, Lightman SL. Glucocorticoid ultradian rhythmicity directs cyclical gene pulsing of the clock gene period 1 in rat hippocampus. Journal of Neuroendocrinology. 22: 1093-100. PMID 20649850 DOI: 10.1111/J.1365-2826.2010.02051.X  0.743
2010 Cameron A, Henley D, Carrell R, Zhou A, Clarke A, Lightman S. Temperature-responsive release of cortisol from its binding globulin: a protein thermocouple. The Journal of Clinical Endocrinology and Metabolism. 95: 4689-95. PMID 20631013 DOI: 10.1210/Jc.2010-0942  0.302
2010 Juruena MF, Cleare AJ, Papadopoulos AS, Poon L, Lightman S, Pariante CM. The prednisolone suppression test in depression: dose-response and changes with antidepressant treatment. Psychoneuroendocrinology. 35: 1486-91. PMID 20558006 DOI: 10.1016/J.Psyneuen.2010.04.016  0.321
2010 Sarabdjitsingh RA, Spiga F, Oitzl MS, Kershaw Y, Meijer OC, Lightman SL, de Kloet ER. Recovery from disrupted ultradian glucocorticoid rhythmicity reveals a dissociation between hormonal and behavioural stress responsiveness. Journal of Neuroendocrinology. 22: 862-71. PMID 20403086 DOI: 10.1111/J.1365-2826.2010.02004.X  0.76
2010 Brant H, Wetherell MA, Lightman S, Crown A, Vedhara K. An exploration into physiological and self-report measures of stress in pre-registration doctors at the beginning and end of a clinical rotation. Stress (Amsterdam, Netherlands). 13: 155-62. PMID 19929317 DOI: 10.3109/10253890903093778  0.328
2009 Evuarherhe O, Leggett J, Waite E, Kershaw Y, Lightman S. Reversal of the hypothalamo-pituitary-adrenal response to oestrogens around puberty. The Journal of Endocrinology. 202: 279-85. PMID 19474059 DOI: 10.1677/Joe-09-0175  0.381
2009 Juruena MF, Pariante CM, Papadopoulos AS, Poon L, Lightman S, Cleare AJ. Prednisolone suppression test in depression: prospective study of the role of HPA axis dysfunction in treatment resistance. The British Journal of Psychiatry : the Journal of Mental Science. 194: 342-9. PMID 19336786 DOI: 10.1192/Bjp.Bp.108.050278  0.304
2009 Shufflebotham J, Wetherell MA, Hince D, Hood S, Lightman S, Nutt D, Probert C, Potokar J. Women with diarrhoea-predominant irritable bowel syndrome show an increased pressure response to 35% carbon dioxide stress challenge. Stress (Amsterdam, Netherlands). 12: 30-6. PMID 18609306 DOI: 10.1080/10253890801976926  0.334
2008 Chen J, Young S, Subburaju S, Sheppard J, Kiss A, Atkinson H, Wood S, Lightman S, Serradeil-Le Gal C, Aguilera G. Vasopressin does not mediate hypersensitivity of the hypothalamic pituitary adrenal axis during chronic stress. Annals of the New York Academy of Sciences. 1148: 349-59. PMID 19120128 DOI: 10.1196/Annals.1410.037  0.382
2007 Conway-Campbell BL, McKenna MA, Wiles CC, Atkinson HC, de Kloet ER, Lightman SL. Proteasome-dependent down-regulation of activated nuclear hippocampal glucocorticoid receptors determines dynamic responses to corticosterone. Endocrinology. 148: 5470-7. PMID 17690167 DOI: 10.1210/en.2007-0585  0.615
2007 Vedhara K, Miles J, Crown A, McCarthy A, Shanks N, Davies D, Lightman S, Davey-Smith G, Ben-Shlomo Y. Relationship of early childhood illness with adult cortisol in the Barry Caerphilly Growth (BCG) cohort. Psychoneuroendocrinology. 32: 865-73. PMID 17669595 DOI: 10.1016/J.Psyneuen.2007.06.006  0.302
2006 Uney JB, Lightman SL. MicroRNAs and osmotic regulation. Proceedings of the National Academy of Sciences of the United States of America. 103: 15278-9. PMID 17030813 DOI: 10.1073/Pnas.0607655103  0.523
2006 Herbert J, Goodyer IM, Grossman AB, Hastings MH, de Kloet ER, Lightman SL, Lupien SJ, Roozendaal B, Seckl JR. Do corticosteroids damage the brain? Journal of Neuroendocrinology. 18: 393-411. PMID 16684130 DOI: 10.1111/J.1365-2826.2006.01429.X  0.574
2005 Bowe JE, Li XF, Kinsey-Jones JS, Paterson S, Brain SD, Lightman SL, O'Byrne KT. Calcitonin gene-related peptide-induced suppression of luteinizing hormone pulses in the rat: the role of endogenous opioid peptides. The Journal of Physiology. 566: 921-8. PMID 15905218 DOI: 10.1113/Jphysiol.2005.085662  0.328
2004 Kaye J, Soothill P, Hunt M, Lightman S. Responses to the 35% CO challenge in postpartum women. Clinical Endocrinology. 61: 582-8. PMID 15521960 DOI: 10.1111/J.1365-2265.2004.02133.X  0.345
2004 Pariante CM, Papadopoulos AS, Poon L, Cleare AJ, Checkley SA, English J, Kerwin RW, Lightman S. Four days of citalopram increase suppression of cortisol secretion by prednisolone in healthy volunteers. Psychopharmacology. 177: 200-6. PMID 15179544 DOI: 10.1007/S00213-004-1925-4  0.327
2003 Vedhara K, Miles J, Bennett P, Plummer S, Tallon D, Brooks E, Gale L, Munnoch K, Schreiber-Kounine C, Fowler C, Lightman S, Sammon A, Rayter Z, Farndon J. An investigation into the relationship between salivary cortisol, stress, anxiety and depression. Biological Psychology. 62: 89-96. PMID 12581685 DOI: 10.1016/S0301-0511(02)00128-X  0.317
2000 Adams EF, Law H, Buchfelder M, Fahlbusch R, Lightman S, Levy A. Presence of GHRH mRNA in human pituitary somatotrophinomas and its relationship to in vitro effect of a GHRH-antagonist on GH secretion and cAMP production. Pituitary. 1: 7-12. PMID 11081178 DOI: 10.1023/A:1009917306289  0.305
2000 Vedhara K, Shanks N, Anderson S, Lightman S. The role of stressors and psychosocial variables in the stress process: A study of chronic caregiver stress Psychosomatic Medicine. 62: 374-385. PMID 10845351 DOI: 10.1097/00006842-200005000-00011  0.324
1999 Geddes BJ, Harding TC, Lightman SL, Uney JB. Assessing viral gene therapy in neuroendocrine models. Frontiers in Neuroendocrinology. 20: 296-316. PMID 10569280 DOI: 10.1006/Frne.1999.0184  0.543
1997 Geddes BJ, Harding TC, Lightman SL, Uney JB. Long-term gene therapy in the CNS: reversal of hypothalamic diabetes insipidus in the Brattleboro rat by using an adenovirus expressing arginine vasopressin. Nature Medicine. 3: 1402-4. PMID 9396613 DOI: 10.1038/Nm1297-1402  0.545
1997 Nicot A, Rowe WB, De Kloet ER, Betancur C, Jessop DS, Lightman SL, Quirion R, Rostène W, Bérod A. Endogenous neurotensin regulates hypothalamic-pituitary-adrenal axis activity and peptidergic neurons in the rat hypothalamic paraventricular nucleus. Journal of Neuroendocrinology. 9: 263-9. PMID 9147289 DOI: 10.1046/J.1365-2826.1997.00581.X  0.621
1997 Ingram C, Windle R, Gamble L, Wood S, Herlihy Y, Shanks N, Lightman S. Oxytocin: a modulator of the endocrine and behavioural responses to stress Behavioural Pharmacology. 8: 651. DOI: 10.1097/00008877-199711000-00044  0.334
1996 Geddes BJ, Harding TC, Hughes DS, Byrnes AP, Lightman SL, Conde G, Uney JB. Persistent transgene expression in the hypothalamus following stereotaxic delivery of a recombinant adenovirus: suppression of the immune response with cyclosporin. Endocrinology. 137: 5166-9. PMID 8895393 DOI: 10.1210/Endo.137.11.8895393  0.539
1995 Baker B, Levy A, Hall L, Lightman S. Cloning and expression of melanin-concentrating hormone genes in the rainbow trout brain. Neuroendocrinology. 61: 67-76. PMID 7731499 DOI: 10.1159/000126814  0.316
1994 Mullens L, Marriott DR, Young KA, Tannahill L, Lightman SL, Wilkin GP. Up-regulation of lipocortin-1 and its mRNA in reactive astrocytes in kainate-lesioned rat cerebellum. Journal of Neuroimmunology. 50: 25-33. PMID 8300854 DOI: 10.1016/0165-5728(94)90211-9  0.539
Low-probability matches (unlikely to be authored by this person)
2004 Kumari M, Grahame-Clarke C, Shanks N, Marmot M, Lightman S, Vallance P. Chronic stress accelerates atherosclerosis in the apolipoprotein E deficient mouse. Stress (Amsterdam, Netherlands). 6: 297-9. PMID 14660062 DOI: 10.1080/10253890310001619461  0.298
1987 Vallejo M, Jackson T, Lightman S, Hanley MR. Occurrence and extracellular actions of inositol pentakis- and hexakisphosphate in mammalian brain. Nature. 330: 656-8. PMID 3683585 DOI: 10.1038/330656A0  0.297
2018 Kalafatakis K, Russell G, Lightman S. MECHANISMS IN ENDOCRINOLOGY: Does circadian and ultradian glucocorticoid exposure affect the brain? European Journal of Endocrinology. PMID 30481157 DOI: 10.1530/EJE-18-0853  0.295
2014 Spiga F, Walker JJ, Terry JR, Lightman SL. HPA axis-rhythms. Comprehensive Physiology. 4: 1273-98. PMID 24944037 DOI: 10.1002/cphy.c140003  0.295
1983 Lightman S, Forsling M, Todd K. Hypothalamic integration of dopaminergic and opiate pathways controlling vasopressin secretion. Endocrinology. 113: 77-80. PMID 6861716 DOI: 10.1210/Endo-113-1-77  0.295
2015 Russell GM, Kalafatakis K, Lightman SL. The importance of biological oscillators for hypothalamic-pituitary-adrenal activity and tissue glucocorticoid response: coordinating stress and neurobehavioural adaptation. Journal of Neuroendocrinology. 27: 378-88. PMID 25494867 DOI: 10.1111/jne.12247  0.295
2007 Spiga F, Harrison LR, Wood SA, Atkinson HC, MacSweeney CP, Thomson F, Craighead M, Grassie M, Lightman SL. Effect of the glucocorticoid receptor antagonist Org 34850 on basal and stress-induced corticosterone secretion. Journal of Neuroendocrinology. 19: 891-900. PMID 17927667 DOI: 10.1111/j.1365-2826.2007.01605.x  0.293
2006 Li XF, Bowe J, Kinsey-Jones J, Brain S, Lightman S, O’Byrne K. The medial preoptic area is unlikely to mediate the CGRP-induced suppression of pulsatile LH secretion in the rat Frontiers in Neuroendocrinology. 27: 67. DOI: 10.1016/J.Yfrne.2006.03.139  0.291
2001 Connan F, Campbell I, Lightman S, Landau S, Wheeler M, Treasure J. Corticotrophin Releasing Hormone (CRH) and the Pathogenesis of Anorexia Nervosa Clinical Science. 101: 18P-18P. DOI: 10.1042/Cs101018Pa  0.291
2008 Droste SK, de Groote L, Atkinson HC, Lightman SL, Reul JM, Linthorst AC. Corticosterone levels in the brain show a distinct ultradian rhythm but a delayed response to forced swim stress. Endocrinology. 149: 3244-53. PMID 18356272 DOI: 10.1210/en.2008-0103  0.289
2011 Li XF, Lin YS, Kinsey-Jones JS, Milligan SR, Lightman SL, O'Byrne KT. The role of the bed nucleus of the stria terminalis in stress-induced inhibition of pulsatile luteinising hormone secretion in the female rat. Journal of Neuroendocrinology. 23: 3-11. PMID 21073554 DOI: 10.1111/j.1365-2826.2010.02071.x  0.288
1989 Murphy D, Levy A, Lightman S, Carter D. Vasopressin RNA in the neural lobe of the pituitary: dramatic accumulation in response to salt loading. Proceedings of the National Academy of Sciences of the United States of America. 86: 9002-5. PMID 2479034 DOI: 10.1073/Pnas.86.22.9002  0.288
2013 Gardner MP, Lightman S, Sayer AA, Cooper C, Cooper R, Deeg D, Ebrahim S, Gallacher J, Kivimaki M, Kumari M, Kuh D, Martin RM, Peeters G, Ben-Shlomo Y. Dysregulation of the hypothalamic pituitary adrenal (HPA) axis and physical performance at older ages: an individual participant meta-analysis. Psychoneuroendocrinology. 38: 40-9. PMID 22658392 DOI: 10.1016/J.Psyneuen.2012.04.016  0.287
1984 Ealey PA, Marshall NJ, Lawton N, Dandona P, Lightman S, Ekins RP. The application of a cytochemical bioassay to measure thyroid stimulating antibodies; a study of patients with euthyroid Graves’ ophthalmopathy Journal of Endocrinological Investigation: Official Journal of the Italian Society of Endocrinology. 7: 597-602. PMID 6152273 DOI: 10.1007/Bf03349492  0.285
2005 Smith GD, Ben-Shlomo Y, Beswick A, Yarnell J, Lightman S, Elwood P. Cortisol, testosterone, and coronary heart disease: prospective evidence from the Caerphilly study. Circulation. 112: 332-40. PMID 16009799 DOI: 10.1161/Circulationaha.104.489088  0.285
2014 Li XF, Hu MH, Li SY, Geach C, Hikima A, Rose S, Greenwood MP, Greenwood M, Murphy D, Poston L, Lightman SL, O'Byrne KT. Overexpression of corticotropin releasing factor in the central nucleus of the amygdala advances puberty and disrupts reproductive cycles in female rats. Endocrinology. 155: 3934-44. PMID 25051447 DOI: 10.1210/En.2014-1339  0.285
2009 Lowry CA, Lightman SL, Nutt DJ. That warm fuzzy feeling: brain serotonergic neurons and the regulation of emotion. Journal of Psychopharmacology (Oxford, England). 23: 392-400. PMID 19074539 DOI: 10.1177/0269881108099956  0.285
2007 Yau JL, Noble J, Thomas S, Kerwin R, Morgan PE, Lightman S, Seckl JR, Pariante CM. The antidepressant desipramine requires the ABCB1 (Mdr1)-type p-glycoprotein to upregulate the glucocorticoid receptor in mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 32: 2520-9. PMID 17356567 DOI: 10.1038/Sj.Npp.1301389  0.284
2004 Mahajan T, Crown A, Checkley S, Farmer A, Lightman S. Atypical depression in growth hormone deficient adults, and the beneficial effects of growth hormone treatment on depression and quality of life. European Journal of Endocrinology / European Federation of Endocrine Societies. 151: 325-32. PMID 15362961 DOI: 10.1530/Eje.0.1510325  0.283
2013 Leggett J, Harper E, Waite E, Marks P, Martinez A, Lightman S. GHRH receptor-targeted botulinum neurotoxin selectively inhibits pulsatile GH secretion in male rats. Endocrinology. 154: 3305-18. PMID 23825127 DOI: 10.1210/En.2012-2175  0.283
2000 Evans J, Platts H, Lightman S, Nutt D. Impulsiveness and the prolactin response to d-fenfluramine. Psychopharmacology. 149: 147-152. PMID 10805609 DOI: 10.1007/S002139900361  0.282
2004 Li XF, Bowe JE, Mitchell JC, Brain SD, Lightman SL, O'Byrne KT. Stress-induced suppression of the gonadotropin-releasing hormone pulse generator in the female rat: a novel neural action for calcitonin gene-related peptide. Endocrinology. 145: 1556-63. PMID 14736738 DOI: 10.1210/en.2003-1609  0.282
2014 Russell GM, Durant C, Ataya A, Papastathi C, Bhake R, Woltersdorf W, Lightman S. Subcutaneous pulsatile glucocorticoid replacement therapy. Clinical Endocrinology. 81: 289-93. PMID 24735400 DOI: 10.1111/cen.12470  0.278
2020 Lightman SL, Birnie MT, Conway-Campbell BL. Dynamics of ACTH and cortisol secretion and implications for disease. Endocrine Reviews. PMID 32060528 DOI: 10.1210/endrev/bnaa002  0.278
2013 Juruena MF, Pariante CM, Papadopoulos AS, Poon L, Lightman S, Cleare AJ. The role of mineralocorticoid receptor function in treatment-resistant depression. Journal of Psychopharmacology (Oxford, England). 27: 1169-79. PMID 23904409 DOI: 10.1177/0269881113499205  0.277
1981 Mullen PE, Lightman S, Linsell C, McKeon P, Sever PS, Todd K. Rhythms of plasma noradrenaline in man. Psychoneuroendocrinology. 6: 213-22. PMID 7291433 DOI: 10.1016/0306-4530(81)90030-5  0.277
2011 Spiga F, Waite EJ, Liu Y, Kershaw YM, Aguilera G, Lightman SL. ACTH-dependent ultradian rhythm of corticosterone secretion. Endocrinology. 152: 1448-57. PMID 21303945 DOI: 10.1210/en.2010-1209  0.277
2012 Rankin J, Walker JJ, Windle R, Lightman SL, Terry JR. Characterizing dynamic interactions between ultradian glucocorticoid rhythmicity and acute stress using the phase response curve. Plos One. 7: e30978. PMID 22363526 DOI: 10.1371/journal.pone.0030978  0.277
2000 Pinkney JH, Goodrick SJ, Katz JR, Johnson AB, Lightman SL, Coppack SW, Medbak S, Mohamed-Ali V. Thyroid and sympathetic influences on plasma leptin in hypothyroidism and hyperthyroidism. International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association For the Study of Obesity. 24: S165-6. PMID 10997647 DOI: 10.1038/Sj.Ijo.0801316  0.277
1980 Lightman S, Maguire A, Jacobs H. Evidence for Opioid Control of Menopausal Flushing and Luteinizing Hormone Pulses Clinical Science. 59: 19P-19P. DOI: 10.1042/Cs059019Pa  0.276
2013 Gibbison B, Angelini GD, Lightman SL. Dynamic output and control of the hypothalamic-pituitary-adrenal axis in critical illness and major surgery. British Journal of Anaesthesia. 111: 347-60. PMID 23661405 DOI: 10.1093/bja/aet077  0.276
2012 Andrews MH, Wood SA, Windle RJ, Lightman SL, Ingram CD. Acute glucocorticoid administration rapidly suppresses basal and stress-induced hypothalamo-pituitary-adrenal axis activity. Endocrinology. 153: 200-11. PMID 22087024 DOI: 10.1210/en.2011-1434  0.275
2018 Gjerstad JK, Lightman SL, Spiga F. Role of glucocorticoid negative feedback in the regulation of HPA axis pulsatility. Stress (Amsterdam, Netherlands). 1-14. PMID 29764284 DOI: 10.1080/10253890.2018.1470238  0.275
2008 Lightman S. The Minder Brain Journal of Anatomy. 212: 702-702. DOI: 10.1111/J.1469-7580.2008.00874.X  0.274
1984 Canepa-Anson R, Williams M, Marshall J, Mitsuoka T, Lightman S, Sutton R. Mechanism of polyuria and natriuresis in atrioventricular nodal tachycardia. Bmj. 289: 866-868. PMID 6434116 DOI: 10.1136/Bmj.289.6449.866  0.274
1993 Aguilera G, Lightman SL, Kiss A. Regulation of the hypothalamic-pituitary-adrenal axis during water deprivation. Endocrinology. 132: 241-8. PMID 8380375 DOI: 10.1210/ENDO.132.1.8380375  0.273
2015 Walker JJ, Spiga F, Gupta R, Zhao Z, Lightman SL, Terry JR. Rapid intra-adrenal feedback regulation of glucocorticoid synthesis. Journal of the Royal Society, Interface / the Royal Society. 12: 20140875. PMID 25392395 DOI: 10.1098/rsif.2014.0875  0.272
2014 Gibbison B, Walker J, Russell G, Stevenson K, Kershaw Y, Asimakopoulos G, Angelini G, Lightman S. Cortisol and ACTH pulsatility is maintained during and after major cardiac surgery F1000research. 5. DOI: 10.7490/F1000Research.1095111.1  0.271
2000 Nolan LA, Windle RJ, Wood SA, Kershaw YM, Lunness HR, Lightman SL, Ingram CD, Levy A. Chronic iodine deprivation attenuates stress-induced and diurnal variation in corticosterone secretion in female Wistar rats. Journal of Neuroendocrinology. 12: 1149-59. PMID 11106971 DOI: 10.1046/j.1365-2826.2000.00569.x  0.27
1993 Clarke I, Jessop D, Millar R, Morris M, Bloom S, Lightman S, Coen CW, Lew R, Smith I. Many peptides that are present in the external zone of the median eminence are not secreted into the hypophysial portal blood of sheep. Neuroendocrinology. 57: 765-75. PMID 7692337 DOI: 10.1159/000126435  0.27
2012 Walker JJ, Spiga F, Waite E, Zhao Z, Kershaw Y, Terry JR, Lightman SL. The origin of glucocorticoid hormone oscillations. Plos Biology. 10: e1001341. PMID 22679394 DOI: 10.1371/journal.pbio.1001341  0.27
2009 Kinsey-Jones JS, Li XF, Knox AM, Wilkinson ES, Zhu XL, Chaudhary AA, Milligan SR, Lightman SL, O'Byrne KT. Down-regulation of hypothalamic kisspeptin and its receptor, Kiss1r, mRNA expression is associated with stress-induced suppression of luteinising hormone secretion in the female rat. Journal of Neuroendocrinology. 21: 20-9. PMID 19094090 DOI: 10.1111/J.1365-2826.2008.01807.X  0.269
2015 Dénes J, Swords F, Rattenberry E, Stals K, Owens M, Cranston T, Xekouki P, Moran L, Kumar A, Wassif C, Fersht N, Baldeweg SE, Morris D, Lightman S, Agha A, et al. Heterogeneous genetic background of the association of pheochromocytoma/paraganglioma and pituitary adenoma: results from a large patient cohort. The Journal of Clinical Endocrinology and Metabolism. 100: E531-41. PMID 25494863 DOI: 10.1210/Jc.2014-3399  0.268
1993 Lightman SL, Harbuz MS. Expression of corticotropin-releasing factor mRNA in response to stress. Ciba Foundation Symposium. 172: 173-87; discussion 1. PMID 8491086 DOI: 10.1002/9780470514368.CH9  0.267
2002 Pariante CM, Papadopoulos AS, Poon L, Checkley SA, English J, Kerwin RW, Lightman S. A novel prednisolone suppression test for the hypothalamic-pituitary-adrenal axis. Biological Psychiatry. 51: 922-30. PMID 12022966 DOI: 10.1016/S0006-3223(01)01314-2  0.267
2002 Fernandes GA, Perks P, Cox NKM, Lightman SL, Ingram CD, Shanks N. Habituation and cross-sensitization of stress-induced hypothalamic-pituitary-adrenal activity: Effect of lesions in the paraventricular nucleus of the thalamus or bed nuclei of the stria terminalis Journal of Neuroendocrinology. 14: 593-602. PMID 12121498 DOI: 10.1046/j.1365-2826.2002.00819.x  0.267
2011 Gardner M, Smith G, Lightman S, Gallacher J, Kuh D, Ebrahim S, Bayer T. Testosterone, Cortisol: Testosterone Ratio And Physical Performance In Later Life: Results From The Caerphilly Prospective Study (Caps) Journal of Epidemiology and Community Health. 65. DOI: 10.1136/Jech.2011.142976G.19  0.267
1989 Lightman SL, Young WS. Lactation inhibits stress-mediated secretion of corticosterone and oxytocin and hypothalamic accumulation of corticotropin-releasing factor and enkephalin messenger ribonucleic acids. Endocrinology. 124: 2358-64. PMID 2785027 DOI: 10.1210/ENDO-124-5-2358  0.266
1992 Jessop D, Biswas S, D'Souza L, Chowdrey H, Lightman S. Neuropeptide Y immunoreactivity in the spleen and thymus of normal rats and following adjuvant-induced arthritis Neuropeptides. 23: 203-207. PMID 1475028 DOI: 10.1016/0143-4179(92)90125-G  0.265
2020 Zavala E, Voliotis M, Zerenner T, Tabak J, Walker JJ, Li XF, Terry JR, Lightman SL, O'Byrne K, Tsaneva-Atanasova K. Dynamic Hormone Control of Stress and Fertility. Frontiers in Physiology. 11: 598845. PMID 33329048 DOI: 10.3389/fphys.2020.598845  0.265
2009 Waite E, Kershaw Y, Spiga F, Lightman SL. A glucocorticoid sensitive biphasic rhythm of testosterone secretion. Journal of Neuroendocrinology. 21: 737-41. PMID 19602101 DOI: 10.1111/j.1365-2826.2009.01900.x  0.264
2018 Adekunbi DA, Li XF, Lass G, Shetty K, Adegoke OA, Yeo SH, Colledge WH, Lightman SL, O'Byrne KT. Kisspeptin neurones in the posterodorsal medial amygdala modulate sexual partner preference and anxiety in male mice. Journal of Neuroendocrinology. PMID 29356147 DOI: 10.1111/Jne.12572  0.263
1999 Harbuz MS, Windle RJ, Jessop DS, Renshaw D, Ingram CD, Lightman SL. Differential effects of psychological and immunological challenge on the hypothalamo-pituitary-adrenal axis function in adjuvant-induced arthritis Annals of the New York Academy of Sciences. 876: 43-52. PMID 10415592 DOI: 10.1111/j.1749-6632.1999.tb07621.x  0.263
2003 Li XF, Mitchell JC, Wood S, Coen CW, Lightman SL, O'Byrne KT. The effect of oestradiol and progesterone on hypoglycaemic stress-induced suppression of pulsatile luteinizing hormone release and on corticotropin-releasing hormone mRNA expression in the rat. Journal of Neuroendocrinology. 15: 468-76. PMID 12694372 DOI: 10.1046/j.1365-2826.2003.01014.x  0.262
2010 Walker JJ, Terry JR, Lightman SL. Origin of ultradian pulsatility in the hypothalamic-pituitary-adrenal axis. Proceedings. Biological Sciences / the Royal Society. 277: 1627-33. PMID 20129987 DOI: 10.1098/rspb.2009.2148  0.262
2005 Crown A, Lightman S. Management of patients with glucocorticoid deficiency. Nature Clinical Practice. Endocrinology & Metabolism. 1: 62-3. PMID 16929369 DOI: 10.1038/Ncpendmet0051  0.262
1990 Lightman S. Central nervous system control of fluid balance: physiology and pathology. Acta Neurochirurgica. Supplementum. 47: 90-4. PMID 2407061 DOI: 10.1007/978-3-7091-9062-3_11  0.261
2020 Spiga F, Zhao Z, Lightman SL. Long-term treatment with the synthetic glucocorticoid methylprednisolone affects adrenal steroidogenic function and response to inflammatory stress in the rat. Brain, Behavior, and Immunity. PMID 32156515 DOI: 10.1016/j.bbi.2020.03.001  0.26
2013 Windle RJ, Wood SA, Kershaw YM, Lightman SL, Ingram CD. Adaptive changes in basal and stress-induced HPA activity in lactating and post-lactating female rats. Endocrinology. 154: 749-61. PMID 23295739 DOI: 10.1210/en.2012-1779  0.26
1998 Ma XM, Lightman SL. The arginine vasopressin and corticotrophin-releasing hormone gene transcription responses to varied frequencies of repeated stress in rats. The Journal of Physiology. 605-14. PMID 9706007 DOI: 10.1111/j.1469-7793.1998.605bk.x  0.259
1986 Kenny RA, Lyon C, Bayliss J, Dixon S, Lightman S, Sutton R. Reduced Plasma Renin Activity in Elderly Subjects in Response to Vasovagal Hypotension and Head Up Tilt Clinical Science. 70: 25P-25P. DOI: 10.1042/Cs070025Pa  0.259
2004 Windle RJ, Kershaw YM, Shanks N, Wood SA, Lightman SL, Ingram CD. Oxytocin attenuates stress-induced c-fos mRNA expression in specific forebrain regions associated with modulation of hypothalamo-pituitary-adrenal activity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 2974-82. PMID 15044536 DOI: 10.1523/JNEUROSCI.3432-03.2004  0.258
2009 Evuarherhe O, Leggett JD, Waite EJ, Kershaw YM, Atkinson HC, Lightman SL. Organizational role for pubertal androgens on adult hypothalamic-pituitary-adrenal sensitivity to testosterone in the male rat. The Journal of Physiology. 587: 2977-85. PMID 19403614 DOI: 10.1113/jphysiol.2008.168393  0.258
2012 Waite EJ, McKenna M, Kershaw Y, Walker JJ, Cho K, Piggins HD, Lightman SL. Ultradian corticosterone secretion is maintained in the absence of circadian cues. The European Journal of Neuroscience. 36: 3142-50. PMID 22823558 DOI: 10.1111/j.1460-9568.2012.08213.x  0.258
2010 Russell GM, Henley DE, Leendertz J, Douthwaite JA, Wood SA, Stevens A, Woltersdorf WW, Peeters BW, Ruigt GS, White A, Veldhuis JD, Lightman SL. Rapid glucocorticoid receptor-mediated inhibition of hypothalamic-pituitary-adrenal ultradian activity in healthy males. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 6106-15. PMID 20427668 DOI: 10.1523/JNEUROSCI.5332-09.2010  0.258
1998 Windle RJ, Wood SA, Shanks N, Lightman SL, Ingram CD. Ultradian rhythm of basal corticosterone release in the female rat: Dynamic interaction with the response to acute stress Endocrinology. 139: 443-450. PMID 9449609 DOI: 10.1210/ENDO.139.2.5721  0.257
2019 Gardner M, Lightman S, Kuh D, Comijs H, Deeg D, Gallacher J, Geoffroy MC, Kivimaki M, Kumari M, Power C, Hardy R, Richards M, Ben-Shlomo Y. Dysregulation of the hypothalamic pituitary adrenal (HPA) axis and cognitive capability at older ages: individual participant meta-analysis of five cohorts. Scientific Reports. 9: 4555. PMID 30872618 DOI: 10.1038/S41598-019-40566-X  0.257
1986 Kenny RA, Lyon C, Ingram A, Morley C, Lightman S, Sutton R. Enhanced Vagal Activity in Carotid Sinus Syndrome and Unexplained Syncope in Response to Tilt Implications for a Central Abnormality in Carotid Sinus Hypersensitivity Clinical Science. 70: 36P-36P. DOI: 10.1042/Cs070036P  0.257
2001 Windle RJ, Wood SA, Kershaw YM, Lightman SL, Ingram CD, Harbuz MS. Increased corticosterone pulse frequency during adjuvant-induced arthritis and its relationship to alterations in stress responsiveness Journal of Neuroendocrinology. 13: 905-911. PMID 11679059 DOI: 10.1046/j.1365-2826.2001.00715.x  0.256
1997 Windle RJ, Brady MM, Kunanandam T, Da Costa AP, Wilson BC, Harbuz M, Lightman SL, Ingram CD. Reduced response of the hypothalamo-pituitary-adrenal axis to alpha1-agonist stimulation during lactation. Endocrinology. 138: 3741-8. PMID 9275060 DOI: 10.1210/Endo.138.9.5405  0.256
2014 Grachev P, Li XF, Hu MH, Li SY, Millar RP, Lightman SL, O'Byrne KT. Neurokinin B signaling in the female rat: a novel link between stress and reproduction. Endocrinology. 155: 2589-601. PMID 24708241 DOI: 10.1210/En.2013-2038  0.255
2004 Seale JV, Wood SA, Atkinson HC, Harbuz MS, Lightman SL. Gonadal steroid replacement reverses gonadectomy-induced changes in the corticosterone pulse profile and stress-induced hypothalamic-pituitary-adrenal axis activity of male and female rats. Journal of Neuroendocrinology. 16: 989-98. PMID 15667454 DOI: 10.1111/j.1365-2826.2004.01258.x  0.255
2012 Lin YS, Li XF, Shao B, Hu MH, Goundry AL, Jeyaram A, Lightman SL, O'Byrne KT. The role of GABAergic signalling in stress-induced suppression of gonadotrophin-releasing hormone pulse generator frequency in female rats. Journal of Neuroendocrinology. 24: 477-88. PMID 22172044 DOI: 10.1111/J.1365-2826.2011.02270.X  0.254
2006 Li XF, Bowe JE, Kinsey-Jones JS, Brain SD, Lightman SL, O'Byrne KT. Differential role of corticotrophin-releasing factor receptor types 1 and 2 in stress-induced suppression of pulsatile luteinising hormone secretion in the female rat. Journal of Neuroendocrinology. 18: 602-10. PMID 16867181 DOI: 10.1111/J.1365-2826.2006.01450.X  0.254
1982 Lightman S, Langdon N, Todd K, Forsling M. Naloxone increases the nicotine-stimulated rise of vasopressin secretion in man. Clinical Endocrinology. 16: 353-8. PMID 7094361 DOI: 10.1111/J.1365-2265.1982.Tb00727.X  0.254
2006 Juruena MF, Cleare AJ, Papadopoulos AS, Poon L, Lightman S, Pariante CM. Different responses to dexamethasone and prednisolone in the same depressed patients. Psychopharmacology. 189: 225-35. PMID 17016711 DOI: 10.1007/S00213-006-0555-4  0.254
1998 Evans P, Broughton-Pipkin F, Lightman S, O'Hare J. Role of the Renin-Aldosterone System in the Reduced Nocturnal Natriuresis of Normal Man Clinical Science. 94: 10P-10P. DOI: 10.1042/Cs094010Pb  0.252
2018 Dzogang F, Lightman S, Cristianini N. Diurnal variations of psychometric indicators in Twitter content. Plos One. 13: e0197002. PMID 29924814 DOI: 10.1371/Journal.Pone.0197002  0.251
2011 Lin Y, Li X, Lupi M, Kinsey-Jones JS, Shao B, Lightman SL, O'Byrne KT. The role of the medial and central amygdala in stress-induced suppression of pulsatile LH secretion in female rats. Endocrinology. 152: 545-55. PMID 21159851 DOI: 10.1210/en.2010-1003  0.251
2010 O'Keane⁎ V, Lightman S, Marsh M, Pawlby S, Papadoupolos A, Patrick et al. K. Increased pituitary-adrenal activation and shortened gestation in depressed pregnant women Journal of Affective Disorders. 122: S41. DOI: 10.1016/J.Jad.2010.02.025  0.251
1997 Crown A, Lightman S. Growth Hormone in Adults: Physiological and Clinical Aspects Journal of the Royal Society of Medicine. 90: 57-58. DOI: 10.1177/014107689709000121  0.25
2006 Windle RJ, Gamble LE, Kershaw YM, Wood SA, Lightman SL, Ingram CD. Gonadal steroid modulation of stress-induced hypothalamo-pituitary-adrenal activity and anxiety behavior: role of central oxytocin. Endocrinology. 147: 2423-31. PMID 16439458 DOI: 10.1210/en.2005-1079  0.25
1993 Harbuz MS, Chalmers J, De Souza L, Lightman SL. Stress-induced activation of CRF and c-fos mRNAs in the paraventricular nucleus are not affected by serotonin depletion. Brain Research. 609: 167-73. PMID 8389647 DOI: 10.1016/0006-8993(93)90870-S  0.247
2009 Li XF, Kinsey-Jones JS, Cheng Y, Knox AM, Lin Y, Petrou NA, Roseweir A, Lightman SL, Milligan SR, Millar RP, O'Byrne KT. Kisspeptin signalling in the hypothalamic arcuate nucleus regulates GnRH pulse generator frequency in the rat. Plos One. 4: e8334. PMID 20016824 DOI: 10.1371/journal.pone.0008334  0.247
2005 Juruena M, Cleare A, Papadopoulos A, Poon L, Lightman S, Pariante C. P.4.10 Different response to a dexamethasone and prednisolone test in treatment-resistant depressed patients European Neuropsychopharmacology. 15. DOI: 10.1016/S0924-977X(05)80203-2  0.246
1999 Martí O, Harbuz MS, Andrés R, Lightman SL, Armario A. Activation of the hypothalamic-pituitary axis in adrenalectomised rats: potentiation by chronic stress. Brain Research. 821: 1-7. PMID 10064781 DOI: 10.1016/S0006-8993(98)01212-8  0.245
1998 García-García L, Harbuz MS, Manzanares J, Lightman SL, Fuentes JA. RU-486 blocks stress-induced enhancement of proenkephalin gene expression in the paraventricular nucleus of rat hypothalamus. Brain Research. 786: 215-8. PMID 9555022 DOI: 10.1016/S0006-8993(97)01416-9  0.245
2003 Brown NW, Ward A, Surwit R, Tiller J, Lightman S, Treasure JL, Campbell IC. Evidence for metabolic and endocrine abnormalities in subjects recovered from anorexia nervosa. Metabolism: Clinical and Experimental. 52: 296-302. PMID 12647266 DOI: 10.1053/Meta.2003.50067  0.245
2018 Fudulu DP, Schadenberg A, Gibbison B, Jenkins I, Lightman S, Angelini GD, Stoica S. Corticosteroids and Other Anti-Inflammatory Strategies in Pediatric Heart Surgery: A National Survey of Practice. World Journal For Pediatric & Congenital Heart Surgery. 9: 289-293. PMID 29692229 DOI: 10.1177/2150135118762392  0.244
2004 Li XF, Edward J, Mitchell JC, Shao B, Bowes JE, Coen CW, Lightman SL, O'Byrne KT. Differential effects of repeated restraint stress on pulsatile lutenizing hormone secretion in female Fischer, Lewis and Wistar rats. Journal of Neuroendocrinology. 16: 620-7. PMID 15214865 DOI: 10.1111/J.1365-2826.2004.01209.X  0.243
2009 Li XF, Kinsey-Jones JS, Bowe JE, Wilkinson ES, Brain SD, Lightman SL, O'Byrne KT. A role for the medial preoptic area in CGRP-induced suppression of pulsatile LH secretion in the female rat. Stress (Amsterdam, Netherlands). 12: 259-67. PMID 19051122 DOI: 10.1080/10253890802379922  0.243
2015 Lightman S. Cortisol interactions with the brain: It's not the size that counts, but the dynamics. Psychoneuroendocrinology. 61: 2. PMID 26383278 DOI: 10.1016/J.Psyneuen.2015.07.389  0.243
1996 Dayan C, Guilding T, Hearing S, Thomas P, Nelson R, Moss T, Bradshaw J, Levy A, Lightman S. Biochemical cure of recurrent acromegaly by resection of cervical spinal canal metastases. Clinical Endocrinology. 44: 597-602. PMID 8762737 DOI: 10.1046/J.1365-2265.1996.685507.X  0.243
2022 Birnie MT, Eapen AV, Kershaw YM, Lodge D, Collingridge GL, Conway-Campbell BL, Lightman SL. Time of day influences stress hormone response to ketamine. Journal of Neuroendocrinology. e13194. PMID 36056546 DOI: 10.1111/jne.13194  0.243
2005 Li XF, Bowe JE, Lightman SL, O'Byrne KT. Role of corticotropin-releasing factor receptor-2 in stress-induced suppression of pulsatile luteinizing hormone secretion in the rat. Endocrinology. 146: 318-22. PMID 15388651 DOI: 10.1210/en.2004-0950  0.242
1998 Shanks N, Harbuz MS, Jessop DS, Perks P, Moore PM, Lightman SL. Inflammatory disease as chronic stress Annals of the New York Academy of Sciences. 840: 599-607. PMID 9629287 DOI: 10.1111/j.1749-6632.1998.tb09599.x  0.242
1989 Seckl J, Lightman S. Cerebrospinal fluid neurohypophysial peptides in benign intracranial hypertension. Journal of Neurology, Neurosurgery, and Psychiatry. 51: 1538-41. PMID 3221220 DOI: 10.1136/Jnnp.51.12.1538  0.242
1997 Ma XM, Levy A, Lightman SL. Emergence of an isolated arginine vasopressin (AVP) response to stress after repeated restraint: a study of both AVP and corticotropin-releasing hormone messenger ribonucleic acid (RNA) and heteronuclear RNA. Endocrinology. 138: 4351-7. PMID 9322950 DOI: 10.1210/ENDO.138.10.5446  0.241
2003 Levy MJ, Matharu MS, Bhola R, Lightman S, Goadsby PJ. Somatostatin infusion withdrawal: a study of patients with migraine, cluster headache and healthy volunteers. Pain. 102: 235-41. PMID 12670664 DOI: 10.1016/S0304-3959(02)00204-X  0.241
1995 Chowdrey HS, Larsen PJ, Harbuz MS, Lightman SL, Jessop DS. Endogenous substance P inhibits the expression of corticotropin-releasing hormone during a chronic inflammatory stress. Life Sciences. 57: 2021-9. PMID 7475953 DOI: 10.1016/0024-3205(95)02194-N  0.241
2013 Lokhmatkina NV, Feder G, Blake S, Morris R, Powers V, Lightman S. Longitudinal measurement of cortisol in association with mental health and experience of domestic violence and abuse: study protocol. Bmc Psychiatry. 13: 188. PMID 23849084 DOI: 10.1186/1471-244X-13-188  0.241
2009 Stavreva DA, Wiench M, John S, Conway-Campbell BL, McKenna MA, Pooley JR, Johnson TA, Voss TC, Lightman SL, Hager GL. Ultradian hormone stimulation induces glucocorticoid receptor-mediated pulses of gene transcription. Nature Cell Biology. 11: 1093-102. PMID 19684579 DOI: 10.1038/Ncb1922  0.24
1986 Lightman SL, Fox P, Dunne MJ. The effect of SMS 201-995, a long-acting somatostatin analogue, on anterior pituitary function in healthy male volunteers. Scandinavian Journal of Gastroenterology. Supplement. 119: 84-95. PMID 2876510 DOI: 10.3109/00365528609087435  0.24
1999 Rivers C, Levy A, Hancock J, Lightman S, Norman M. Insertion of an Amino Acid in the DNA-Binding Domain of the Glucocorticoid Receptor as a Result of Alternative Splicing The Journal of Clinical Endocrinology and Metabolism. 84: 4283-4286. PMID 10566686 DOI: 10.1210/Jcem.84.11.6235  0.239
2006 Juruena M, Papadopoulos A, Poon L, Lightman S, Cleare A, Pariante C. P.2.a.003 Treatment resistant depression: response to prednisolone supression test European Neuropsychopharmacology. 16: S284-S285. DOI: 10.1016/S0924-977X(06)70283-8  0.238
1999 Ma XM, Lightman SL, Aguilera G. Vasopressin and corticotropin-releasing hormone gene responses to novel stress in rats adapted to repeated restraint. Endocrinology. 140: 3623-32. PMID 10433220 DOI: 10.1210/endo.140.8.6943  0.238
2019 Lansdall-Welfare T, Lightman S, Cristianini N. Seasonal variation in antidepressant prescriptions, environmental light and web queries for seasonal affective disorder. The British Journal of Psychiatry : the Journal of Mental Science. 1-4. PMID 30924435 DOI: 10.1192/Bjp.2019.40  0.238
2004 Seale JV, Wood SA, Atkinson HC, Bate E, Lightman SL, Ingram CD, Jessop DS, Harbuz MS. Gonadectomy reverses the sexually diergic patterns of circadian and stress-induced hypothalamic-pituitary-adrenal axis activity in male and female rats. Journal of Neuroendocrinology. 16: 516-24. PMID 15189326 DOI: 10.1111/j.1365-2826.2004.01195.x  0.238
1987 Lightman S, Rechthand E, Latker C, Palestine A, Rapoport S. Assessment of the permeability of the blood-retinal barrier in hypertensive rats. Hypertension (Dallas, Tex. : 1979). 10: 390-5. PMID 3653967 DOI: 10.1161/01.Hyp.10.4.390  0.237
2009 Knox AM, Li XF, Kinsey-Jones JS, Wilkinson ES, Wu XQ, Cheng YS, Milligan SR, Lightman SL, O'Byrne KT. Neonatal lipopolysaccharide exposure delays puberty and alters hypothalamic Kiss1 and Kiss1r mRNA expression in the female rat. Journal of Neuroendocrinology. 21: 683-9. PMID 19500221 DOI: 10.1111/J.1365-2826.2009.01885.X  0.237
1997 Windle RJ, Wood S, Shanks N, Perks P, Conde GL, Da Costa APC, Ingram CD, Lightman SL. Endocrine and behavioural responses to noise stress: Comparison of virgin and lactating female rats during non-disrupted maternal activity Journal of Neuroendocrinology. 9: 407-414. PMID 9229351 DOI: 10.1046/j.1365-2826.1997.00587.x  0.237
1997 Aguilera G, Jessop DS, Harbuz MS, Kiss A, Lightman SL. Differential regulation of hypothalamic pituitary corticotropin releasing hormone receptors during development of adjuvant-induced arthritis in the rat. The Journal of Endocrinology. 153: 185-91. PMID 9166107 DOI: 10.1677/JOE.0.1530185  0.236
1982 Lightman S, Iversen L, Forsling M. Dopamine and [D-ALA2, D-Leu5]enkephalin inhibit the electrically stimulated neurohypophyseal release of vasopressin in vitro: evidence for calcium-dependent opiate action The Journal of Neuroscience. 2: 78-81. DOI: 10.1523/Jneurosci.02-01-00078.1982  0.236
2015 Spiga F, Lightman SL. Dynamics of adrenal glucocorticoid steroidogenesis in health and disease. Molecular and Cellular Endocrinology. 408: 227-34. PMID 25662280 DOI: 10.1016/j.mce.2015.02.005  0.235
2008 Tyacke RJ, Holmes R, Reid A, Grant EJ, Henry B, Zelaya F, Reul JMHM, Lightman S, Williams SCR, Nutt DJ, Malizia AL. P.1.e.017 Hydrocortisone induces limbic, hippocampal and limbic/paralimbic cerebral perfusion changes as measured by 3T blood oxygenation level dependent (BOLD) phMRI European Neuropsychopharmacology. 18. DOI: 10.1016/S0924-977X(08)70350-X  0.235
2001 da Costa AP, Ma X, Ingram CD, Lightman SL, Aguilera G. Hypothalamic and amygdaloid corticotropin-releasing hormone (CRH) and CRH receptor-1 mRNA expression in the stress-hyporesponsive late pregnant and early lactating rat. Brain Research. Molecular Brain Research. 91: 119-30. PMID 11457499 DOI: 10.1016/S0169-328X(01)00137-1  0.234
1996 Chowdrey HS, Larsen PJ, Harbuz MS, Jessop DS, Aguilera G, Eckland DJ, Lightman SL. Evidence for arginine vasopressin as the primary activator of the HPA axis during adjuvant-induced arthritis. British Journal of Pharmacology. 116: 2417-24. PMID 8581278 DOI: 10.1111/j.1476-5381.1995.tb15089.x  0.234
2017 Hannen R, Udeh-Momoh C, Upton J, Wright M, Michael A, Gulati A, Rajpopat S, Clayton N, Halsall D, Burrin J, Flower R, Sevilla L, Latorre V, Frame J, Lightman S, et al. Dysfunctional Skin-Derived Glucocorticoid Synthesis Is a Pathogenic Mechanism of Psoriasis. The Journal of Investigative Dermatology. PMID 28359725 DOI: 10.1016/J.Jid.2017.02.984  0.234
2010 Kinsey-Jones JS, Li XF, Knox AM, Lin YS, Milligan SR, Lightman SL, O'Byrne KT. Corticotrophin-releasing factor alters the timing of puberty in the female rat. Journal of Neuroendocrinology. 22: 102-9. PMID 20002962 DOI: 10.1111/J.1365-2826.2009.01940.X  0.234
2009 Rivers C, Flynn A, Qian X, Matthews L, Lightman S, Ray D, Norman M. Characterization of conserved tandem donor sites and intronic motifs required for alternative splicing in corticosteroid receptor genes. Endocrinology. 150: 4958-67. PMID 19819975 DOI: 10.1210/En.2009-0346  0.233
2009 Lowry CA, Hale MW, Plant A, Windle RJ, Shanks N, Wood SA, Ingram CD, Renner KJ, Lightman SL, Summers CH. Fluoxetine inhibits corticotropin-releasing factor (CRF)-induced behavioural responses in rats. Stress (Amsterdam, Netherlands). 12: 225-39. PMID 18951247 DOI: 10.1080/10253890802309861  0.233
1990 Fitzpatrick A, Williams T, Jeffery C, Lightman S, Sutton R. Pathogenic role for argenine vasopressin (AVP) and catecholamines (EP & NEP) in vasovagal syncope Journal of the American College of Cardiology. 15: A98. DOI: 10.1016/0735-1097(90)92107-D  0.233
1992 Lightman SL. Alterations in hypothalamic-pituitary responsiveness during lactation. Annals of the New York Academy of Sciences. 652: 340-6. PMID 1320830 DOI: 10.1111/j.1749-6632.1992.tb34365.x  0.233
1994 Larsen PJ, Mikkelsen JD, Jessop D, Lightman SL, Chowdrey HS. Neonatal monosodium glutamate treatment alters both the activity and the sensitivity of the rat hypothalamo-pituitary-adrenocortical axis. The Journal of Endocrinology. 141: 497-503. PMID 8071649 DOI: 10.1677/JOE.0.1410497  0.233
1998 Ward A, Brown N, Lightman S, Campbell IC, Treasure J. Neuroendocrine, appetitive and behavioural responses to d-fenfluramine in women recovered from anorexia nervosa. The British Journal of Psychiatry : the Journal of Mental Science. 172: 351-8. PMID 9715339 DOI: 10.1192/Bjp.172.4.351  0.232
1997 Checkley S, Raven P, O’Dwyer A-, Segovia M, Lightman S, Mulligan O, Cotter P, Reynolds M. Antidepressant effects of metyrapone Biological Psychiatry. 42. DOI: 10.1016/S0006-3223(97)87821-3  0.232
2004 Kaye J, Buchanan F, Kendrick A, Johnson P, Lowry C, Bailey J, Nutt D, Lightman S. Acute carbon dioxide exposure in healthy adults: evaluation of a novel means of investigating the stress response. Journal of Neuroendocrinology. 16: 256-64. PMID 15049856 DOI: 10.1111/J.0953-8194.2004.01158.X  0.232
2002 Lightman SL, Windle RJ, Ma XM, Harbuz MS, Shanks NM, Julian MD, Wood SA, Kershaw YM, Ingram CD. Hypothalamic-pituitary-adrenal function. Archives of Physiology and Biochemistry. 110: 90-3. PMID 11935404 DOI: 10.1076/apab.110.1.90.899  0.232
2012 Grachev P, Li XF, Kinsey-Jones JS, di Domenico AL, Millar RP, Lightman SL, O'Byrne KT. Suppression of the GnRH pulse generator by neurokinin B involves a κ-opioid receptor-dependent mechanism. Endocrinology. 153: 4894-904. PMID 22903614 DOI: 10.1210/En.2012-1574  0.232
1992 Chowdrey HS, Jessop DS, Patel H, Lightman SL. Altered adrenocorticotropin, corticosterone and oxytocin responses to stress during chronic salt load. Neuroendocrinology. 54: 635-8. PMID 1664502 DOI: 10.1159/000125971  0.232
2007 Li XF, Kinsey-Jones JS, Knox AM, Wu XQ, Tahsinsoy D, Brain SD, Lightman SL, O'Byrne KT. Neonatal lipopolysaccharide exposure exacerbates stress-induced suppression of luteinizing hormone pulse frequency in adulthood. Endocrinology. 148: 5984-90. PMID 17872370 DOI: 10.1210/En.2007-0710  0.232
1993 Harbuz MS, Rees RG, Lightman SL. HPA axis responses to acute stress and adrenalectomy during adjuvant-induced arthritis in the rat. The American Journal of Physiology. 264: R179-85. PMID 8381616 DOI: 10.1152/AJPREGU.1993.264.1.R179  0.232
1985 Williams M, da Costa D, Bannister R, Lightman S, Mathias C. Pressor Effect of Arginine Vasopressin Infusion in Autonomic Failure Clinical Science. 68: 49P-49P. DOI: 10.1042/Cs068049Pa  0.231
2013 Bhake RC, Leendertz JA, Linthorst AC, Lightman SL. Automated 24-hours sampling of subcutaneous tissue free cortisol in humans. Journal of Medical Engineering & Technology. 37: 180-4. PMID 23547774 DOI: 10.3109/03091902.2013.773096  0.231
2012 Qian X, Droste SK, Lightman SL, Reul JM, Linthorst AC. Circadian and ultradian rhythms of free glucocorticoid hormone are highly synchronized between the blood, the subcutaneous tissue, and the brain. Endocrinology. 153: 4346-53. PMID 22822164 DOI: 10.1210/en.2012-1484  0.231
1994 Shi ZX, Levy A, Lightman SL. Thyroid hormone-mediated regulation of corticotropin-releasing hormone messenger ribonucleic acid in the rat. Endocrinology. 134: 1577-80. PMID 8119200 DOI: 10.1210/ENDO.134.3.8119200  0.231
2009 Droste SK, de Groote L, Lightman SL, Reul JM, Linthorst AC. The ultradian and circadian rhythms of free corticosterone in the brain are not affected by gender: an in vivo microdialysis study in Wistar rats. Journal of Neuroendocrinology. 21: 132-40. PMID 19076270 DOI: 10.1111/j.1365-2826.2008.01811.x  0.23
2005 Seale JV, Wood SA, Atkinson HC, Lightman SL, Harbuz MS. Organizational role for testosterone and estrogen on adult hypothalamic-pituitary-adrenal axis activity in the male rat. Endocrinology. 146: 1973-82. PMID 15625243 DOI: 10.1210/en.2004-1201  0.23
2009 Spiga F, Harrison LR, MacSweeney CP, Thomson FJ, Craighead M, Lightman SL. Effect of vasopressin 1b receptor blockade on the hypothalamic-pituitary-adrenal response of chronically stressed rats to a heterotypic stressor. The Journal of Endocrinology. 200: 285-91. PMID 19074473 DOI: 10.1677/JOE-08-0425  0.229
1990 Lightman S, Pinter G, Yuen L, Bradbury M. Permeability changes at blood-retinal barrier in diabetes and effect of aldose reductase inhibition American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 259: R601-R605. PMID 2118733 DOI: 10.1152/Ajpregu.1990.259.3.R601  0.229
2006 Kaye JM, Lightman SL. Corticosteroids and the cardiovascular response to stress: a pilot study of the 35% CO2 challenge in Addison's disease. Clinical Endocrinology. 65: 282-6. PMID 16918945 DOI: 10.1111/j.1365-2265.2006.02589.x  0.229
1987 Todd K, Lightman SL. Vasopressin activation of phosphatidylinositol metabolism in rat anterior pituitary in vitro and its modification by changes in the hypothalamo-pituitary-adrenal axis. Neuroendocrinology. 45: 212-8. PMID 3561697 DOI: 10.1159/000124728  0.229
1993 Stephanou A, Sarlis NJ, Knight RA, Lightman SL, Chowdrey HS. Glucocorticoid-mediated responses of plasma ACTH and anterior pituitary pro-opiomelanocortin, growth hormone and prolactin mRNAs during adjuvant-induced arthritis in the rat. Journal of Molecular Endocrinology. 9: 273-81. PMID 1335726 DOI: 10.1677/JME.0.0090273  0.229
1994 Checkley SA, O'Dwyer A-, Raven P, Taylor N, Lightman S. Antidepressant effects of treatments with metyrapone and hydrocortisone Biological Psychiatry. 35: 711. DOI: 10.1016/0006-3223(94)91003-0  0.229
2008 Atkinson HC, Wood SA, Castrique ES, Kershaw YM, Wiles CC, Lightman SL. Corticosteroids mediate fast feedback of the rat hypothalamic-pituitary-adrenal axis via the mineralocorticoid receptor. American Journal of Physiology. Endocrinology and Metabolism. 294: E1011-22. PMID 18349112 DOI: 10.1152/ajpendo.00721.2007  0.229
1991 Patel H, Chowdrey HS, Lightman SL. Lactation abolishes corticotropin-releasing factor-induced oxytocin secretion in the conscious rat. Endocrinology. 128: 725-7. PMID 1989858 DOI: 10.1210/ENDO-128-2-725  0.228
2004 Young EA, Abelson J, Lightman SL. Cortisol pulsatility and its role in stress regulation and health. Frontiers in Neuroendocrinology. 25: 69-76. PMID 15571755 DOI: 10.1016/j.yfrne.2004.07.001  0.228
2015 Kalafatakis K, Russell GM, Zarros A, Lightman SL. Temporal control of glucocorticoid neurodynamics and its relevance for brain homeostasis, neuropathology and glucocorticoid-based therapeutics. Neuroscience and Biobehavioral Reviews. PMID 26656793 DOI: 10.1016/j.neubiorev.2015.11.009  0.228
2008 Lightman SL, Wiles CC, Atkinson HC, Henley DE, Russell GM, Leendertz JA, McKenna MA, Spiga F, Wood SA, Conway-Campbell BL. The significance of glucocorticoid pulsatility. European Journal of Pharmacology. 583: 255-62. PMID 18339373 DOI: 10.1016/j.ejphar.2007.11.073  0.227
2000 Sowunmi A, Newton CRJC, Waruiru C, Lightman S, Dunger DB. Arginine vasopressin secretion in Kenyan children with severe malaria. Journal of Tropical Pediatrics. 46: 195-199. PMID 10996978 DOI: 10.1093/Tropej/46.4.195  0.226
2002 Grundy PL, Harbuz MS, Jessop DS, Lightman SL, Sharples PM. The hypothalamo-pituitary-adrenal axis response to experimental traumatic brain injury. Journal of Neurotrauma. 18: 1373-81. PMID 11780867 DOI: 10.1089/08977150152725669  0.226
2012 Levy A, Eckland DJ, Gurney AM, Reubi JC, Doshi R, Lightman SL. Somatostatin and Thyrotrophin-Releasing Hormone Response and Receptor Status of a Thyrotrophin-Secreting Pituitary Adenoma: Clinical and in vitro Studies. Journal of Neuroendocrinology. 1: 321-6. PMID 19210422 DOI: 10.1111/j.1365-2826.1989.tb00123.x  0.226
2015 Hu MH, Li XF, McCausland B, Li SY, Gresham R, Kinsey-Jones JS, Gardiner JV, Sam AH, Bloom SR, Poston L, Lightman SL, Murphy KG, O'Byrne KT. Relative Importance of the Arcuate and Anteroventral Periventricular Kisspeptin Neurons in Control of Puberty and Reproductive Function in Female Rats. Endocrinology. 156: 2619-31. PMID 25875299 DOI: 10.1210/En.2014-1655  0.226
2020 Kalafatakis K, Russell GM, Ferguson SG, Grabski M, Harmer CJ, Munafò MR, Marchant N, Wilson A, Brooks JC, Thakrar J, Murphy P, Thai NJ, Lightman SL. Glucocorticoid ultradian rhythmicity differentially regulates mood and resting state networks in the human brain: A randomised controlled clinical trial. Psychoneuroendocrinology. 124: 105096. PMID 33296841 DOI: 10.1016/j.psyneuen.2020.105096  0.226
1997 Ma XM, Levy A, Lightman SL. Rapid changes of heteronuclear RNA for arginine vasopressin but not for corticotropin releasing hormone in response to acute corticosterone administration. Journal of Neuroendocrinology. 9: 723-8. PMID 9355040 DOI: 10.1046/j.1365-2826.1997.00646.x  0.225
1993 Stephanou A, Sarlis NJ, Knight RA, Lightman SL, Chowdrey HS. Effects of cyclosporine A on the hypothalamic-pituitary-adrenal axis and anterior pituitary interleukin-6 mRNA expression during chronic inflammatory stress in the rat. Journal of Neuroimmunology. 41: 215-22. PMID 1334967 DOI: 10.1016/0165-5728(92)90072-S  0.225
2014 Li SY, Li XF, Hu MH, Shao B, Poston L, Lightman SL, O'Byrne KT. Neurokinin B receptor antagonism decreases luteinising hormone pulse frequency and amplitude and delays puberty onset in the female rat. Journal of Neuroendocrinology. 26: 521-7. PMID 24863620 DOI: 10.1111/Jne.12167  0.225
2020 Hodges JK, Lightman SL, Cottingham PG, Shaw HJ. Reversible, long-term inhibition of ovulation with a gonadotropin-releasing hormone antagonist in the marmoset monkey (Callithrix jacchus). American Journal of Primatology. 26: 167-178. PMID 31948156 DOI: 10.1002/AJP.1350260303  0.224
1987 Carter DA, Lightman SL. Diurnal pattern of stress-evoked neurohypophyseal hormone secretion: sexual dimorphism in rats. Neuroscience Letters. 71: 252-5. PMID 3491347 DOI: 10.1016/0304-3940(86)90568-9  0.224
2009 Spiga F, Harrison LR, Wood S, Knight DM, MacSweeney CP, Thomson F, Craighead M, Lightman SL. Blockade of the V(1b) receptor reduces ACTH, but not corticosterone secretion induced by stress without affecting basal hypothalamic-pituitary-adrenal axis activity. The Journal of Endocrinology. 200: 273-83. PMID 19008333 DOI: 10.1677/JOE-08-0421  0.224
2014 Henley DE, Lightman SL. Cardio-metabolic consequences of glucocorticoid replacement: relevance of ultradian signalling. Clinical Endocrinology. 80: 621-8. PMID 24611992 DOI: 10.1111/cen.12422  0.224
2000 Connan F, Lightman S, Treasure J. Biochemical and endocrine complications European Eating Disorders Review. 8: 144-157. DOI: 10.1002/(Sici)1099-0968(200003)8:2<144::Aid-Erv340>3.0.Co;2-B  0.224
1986 Kenny R, Williams T, Rowe P, Williams T, Lyon O, Sutton R, Lightman S. Haemodynamic Changes Associated with Avp Infusion in Man Clinical Science. 71: 12P-12P. DOI: 10.1042/Cs071012Pa  0.223
1989 Harbuz MS, Lightman SL. Glucocorticoid inhibition of stress-induced changes in hypothalamic corticotrophin-releasing factor messenger RNA and proenkephalin A messenger RNA. Neuropeptides. 14: 17-20. PMID 2789345 DOI: 10.1016/0143-4179(89)90029-2  0.223
1981 Lightman SL, Jacobs HS, Maguire AK, McGarrick G, Jeffcoate SL. Climacteric flushing: clinical and endocrine response to infusion of naloxone. British Journal of Obstetrics and Gynaecology. 88: 919-24. PMID 6791684 DOI: 10.1111/j.1471-0528.1981.tb02229.x  0.223
2008 Bowe JE, Li XF, Kinsey-Jones JS, Brain SD, Lightman SL, O'Byrne KT. The role of corticotrophin-releasing hormone receptors in the calcitonin gene-related peptide-induced suppression of pulsatile luteinising hormone secretion in the female rat. Stress (Amsterdam, Netherlands). 11: 312-9. PMID 18574791 DOI: 10.1080/10253890701801448  0.222
2011 Johnson PL, Fitz SD, Hollis JH, Moratalla R, Lightman SL, Shekhar A, Lowry CA. Induction of c-Fos in 'panic/defence'-related brain circuits following brief hypercarbic gas exposure. Journal of Psychopharmacology (Oxford, England). 25: 26-36. PMID 20080924 DOI: 10.1177/0269881109353464  0.222
1997 Windle RJ, Shanks N, Lightman SL, Ingram CD. Central oxytocin administration reduces stress-induced corticosterone release and anxiety behavior in rats Endocrinology. 138: 2829-2834. PMID 9202224 DOI: 10.1210/ENDO.138.7.5255  0.22
1998 Windle RJ, Wood SA, Lightman SL, Ingram CD. The pulsatile characteristics of hypothalamo-pituitary-adrenal activity in female Lewis and Fischer 344 rats and its relationship to differential stress responses Endocrinology. 139: 4044-4052. PMID 9751481 DOI: 10.1210/ENDO.139.10.6238  0.22
2010 Juruena MF, Pariante C, Papadopoulos AS, Poon L, Lightman S, Cleare A. P.2.a.031 Prednisolone suppression test, but not dexamethasone predicts outcome in treatment resistant depression European Neuropsychopharmacology. 20. DOI: 10.1016/S0924-977X(10)70487-9  0.22
2013 Choe HK, Kim HD, Park SH, Lee HW, Park JY, Seong JY, Lightman SL, Son GH, Kim K. Synchronous activation of gonadotropin-releasing hormone gene transcription and secretion by pulsatile kisspeptin stimulation. Proceedings of the National Academy of Sciences of the United States of America. 110: 5677-82. PMID 23509283 DOI: 10.1073/Pnas.1213594110  0.22
2010 Windle RJ, Wood SA, Kershaw YM, Lightman SL, Ingram CD. Reduced stress responsiveness in pregnancy: relationship with pattern of forebrain c-fos mRNA expression. Brain Research. 1358: 102-9. PMID 20732311 DOI: 10.1016/j.brainres.2010.08.041  0.22
2012 Grachev P, Li XF, Lin YS, Hu MH, Elsamani L, Paterson SJ, Millar RP, Lightman SL, O'Byrne KT. GPR54-dependent stimulation of luteinizing hormone secretion by neurokinin B in prepubertal rats. Plos One. 7: e44344. PMID 23028524 DOI: 10.1371/Journal.Pone.0044344  0.22
1989 Harbuz MS, Lightman SL. Responses of hypothalamic and pituitary mRNA to physical and psychological stress in the rat. The Journal of Endocrinology. 122: 705-11. PMID 2809478 DOI: 10.1677/JOE.0.1220705  0.219
1997 Harbuz MS, Conde GL, Marti O, Lightman SL, Jessop DS. The hypothalamic-pituitary-adrenal axis in autoimmunity. Annals of the New York Academy of Sciences. 823: 214-24. PMID 9292047 DOI: 10.1111/j.1749-6632.1997.tb48393.x  0.219
1988 Carter DA, Lightman SL. Oxytocin responses to stress in lactating and hyperprolactinaemic rats. Neuroendocrinology. 46: 532-7. PMID 3696384 DOI: 10.1159/000124876  0.219
2017 Spiga F, Zavala E, Walker JJ, Zhao Z, Terry JR, Lightman SL. Dynamic responses of the adrenal steroidogenic regulatory network. Proceedings of the National Academy of Sciences of the United States of America. PMID 28716938 DOI: 10.1073/pnas.1703779114  0.218
2014 Juruena MF, Cleare AJ, Poon L, Papadopoulos AS, Lightman S, Pariante CM. P.2.b.040 MR and GR balance predicts treatment outcome in treatment resistant depression European Neuropsychopharmacology. 24. DOI: 10.1016/S0924-977X(14)70641-8  0.218
2006 Atkinson HC, Wood SA, Kershaw YM, Bate E, Lightman SL. Diurnal variation in the responsiveness of the hypothalamic-pituitary-adrenal axis of the male rat to noise stress. Journal of Neuroendocrinology. 18: 526-33. PMID 16774501 DOI: 10.1111/j.1365-2826.2006.01444.x  0.218
2020 O'Connor DB, Aggleton JP, Chakrabarti B, Cooper CL, Creswell C, Dunsmuir S, Fiske ST, Gathercole S, Gough B, Ireland JL, Jones MV, Jowett A, Kagan C, Karanika-Murray M, Kaye LK, ... ... Lightman S, et al. Research priorities for the COVID-19 pandemic and beyond: A call to action for psychological science. British Journal of Psychology (London, England : 1953). e12468. PMID 32683689 DOI: 10.1111/Bjop.12468  0.218
2018 Ingram R, Kang H, Lightman S, Jane DE, Bortolotto ZA, Collingridge GL, Lodge D, Volianskis A. Some distorted thoughts about ketamine as a psychedelic and a novel hypothesis based on NMDA receptor-mediated synaptic plasticity. Neuropharmacology. PMID 29885421 DOI: 10.1016/J.Neuropharm.2018.06.008  0.218
1989 Williams T, Noble M, Drake-Holland A, Travill C, Chalmers J, Jeffery C, Lightman S. Mechanism of Impaired Excretion of Fluid Load following Cardiac Denervation in Dogs Clinical Science. 76: 24P-24P. DOI: 10.1042/Cs076024Pa  0.218
1985 Williams M, Da Costa D, Bannister R, Lightman S, Mathias C. Pressor effect of arginine vasopressin in autonomic failure Journal of the Autonomic Nervous System. 14: 107. DOI: 10.1016/0165-1838(85)90142-0  0.218
2002 Argyropoulos SV, Bailey JE, Hood SD, Kendrick AH, Rich AS, Laszlo G, Nash JR, Lightman SL, Nutt DJ. Inhalation of 35% CO2 results in activation of the HPA axis in healthy volunteers Psychoneuroendocrinology. 27: 715-729. PMID 12084664 DOI: 10.1016/S0306-4530(01)00075-0  0.218
1991 Harbuz MS, Chowdrey HS, Jessop DS, Biswas S, Lightman SL. Role of catecholamines in mediating messenger RNA and hormonal responses to stress. Brain Research. 551: 52-7. PMID 1655164 DOI: 10.1016/0006-8993(91)90912-F  0.218
2003 Lowry CA, Plant A, Shanks N, Ingram CD, Lightman SL. Anatomical and functional evidence for a stress-responsive, monoamine-accumulating area in the dorsomedial hypothalamus of adult rat brain. Hormones and Behavior. 43: 254-62. PMID 12614657 DOI: 10.1016/S0018-506X(02)00009-0  0.217
1988 Carter DA, Saridaki E, Lightman SL. Sexual differentiation of oxytocin stress responsiveness: effect of neonatal androgenization, castration and a luteinizing hormone-releasing hormone antagonist. Acta Endocrinologica. 117: 525-30. PMID 3291527 DOI: 10.1530/ACTA.0.1170525  0.217
2010 Atkinson HC, Leggett JD, Wood SA, Castrique ES, Kershaw YM, Lightman SL. Regulation of the hypothalamic-pituitary-adrenal axis circadian rhythm by endocannabinoids is sexually diergic. Endocrinology. 151: 3720-7. PMID 20534730 DOI: 10.1210/en.2010-0101  0.217
2007 Connan F, Lightman SL, Landau S, Wheeler M, Treasure J, Campbell IC. An investigation of hypothalamic-pituitary-adrenal axis hyperactivity in anorexia nervosa: the role of CRH and AVP. Journal of Psychiatric Research. 41: 131-43. PMID 16455105 DOI: 10.1016/J.Jpsychires.2005.12.005  0.217
1990 Harbuz MS, Nicholson SA, Gillham B, Lightman SL. Stress responsiveness of hypothalamic corticotrophin releasing factor and pituitary pro-opiomelanocortin mRNAs following high-dose glucocorticoid treatment and withdrawal in the rat Journal of Endocrinology. 127: 407-415. PMID 2280210 DOI: 10.1677/JOE.0.1270407  0.216
1987 Carter DA, Williams TD, Lightman SL. A sex difference in endogenous opioid regulation of the posterior pituitary response to stress in the rat. The Journal of Endocrinology. 111: 239-44. PMID 3794582 DOI: 10.1677/JOE.0.1110239  0.216
2001 Jessop DS, Harbuz MS, Lightman SL. CRH in chronic inflammatory stress. Peptides. 22: 803-7. PMID 11337094 DOI: 10.1016/S0196-9781(01)00394-1  0.216
2000 Shanks N, Windle RJ, Perks PA, Harbuz MS, Jessop DS, Ingram CD, Lightman SL. Early-life exposure to endotoxin alters hypothalamic-pituitary-adrenal function and predisposition to inflammation Proceedings of the National Academy of Sciences of the United States of America. 97: 5645-5650. PMID 10779563 DOI: 10.1073/pnas.090571897  0.216
1996 Da Costa APC, Wood S, Ingram CD, Lightman SL. Region-specific reduction in stress-induced c-fos mRNA expression during pregnancy and lactation Brain Research. 742: 177-184. PMID 9117393 DOI: 10.1016/S0006-8993(96)00962-6  0.215
1986 Williams TD, Lightman SL, Leadbeater MJ. Hormonal and cardiovascular responses to DDAVP in man. Clinical Endocrinology. 24: 89-96. PMID 3519005 DOI: 10.1111/j.1365-2265.1986.tb03258.x  0.215
2020 Smith LIF, Zhao Z, Walker J, Lightman S, Spiga F. Activation and expression of endogenous CREB-regulated transcription coactivators (CRTC) 1, 2 and 3 in the rat adrenal gland. Journal of Neuroendocrinology. e12920. PMID 33314405 DOI: 10.1111/jne.12920  0.215
1981 Lightman SL, Jacobs HS, Maguire AK, McGarrick G, Jeffcoate SL. Constancy of opioid control of luteinizing hormone in different pathophysiological states. The Journal of Clinical Endocrinology and Metabolism. 52: 1260-3. PMID 6785301 DOI: 10.1210/JCEM-52-6-1260  0.215
1997 Ma XM, Levy A, Lightman SL. Rapid changes in heteronuclear RNA for corticotrophin-releasing hormone and arginine vasopressin in response to acute stress. The Journal of Endocrinology. 152: 81-9. PMID 9014842 DOI: 10.1677/JOE.0.1520081  0.214
1987 Vallejo M, Carter DA, Diez-Guerra FJ, Emson PC, Lightman SL. Neonatal administration of a specific neuropeptide Y antiserum alters the vasopressin response to haemorrhage and the hypothalamic content of noradrenaline in rats. Neuroendocrinology. 45: 507-9. PMID 3614553 DOI: 10.1159/000124782  0.214
2010 Pearson RM, Cooper RM, Penton-Voak IS, Lightman SL, Evans J. Depressive symptoms in early pregnancy disrupt attentional processing of infant emotion. Psychological Medicine. 40: 621-31. PMID 19671214 DOI: 10.1017/S0033291709990961  0.214
1997 Da Costa APC, Kampa RJ, Windle RJ, Ingram CD, Lightman SL. Region-specific immediate-early gene expression following the administration of corticotropin-releasing hormone in virgin and lactating rats Brain Research. 770: 151-162. PMID 9372214 DOI: 10.1016/S0006-8993(97)00764-6  0.214
1990 Travill C, Williams M, Ahmed R, Ingram A, Lightman S, Sutton R. Exercise capacity and neuroendocrine response in four pacing modes — within patient comparison Journal of the American College of Cardiology. 15: A68. DOI: 10.1016/0735-1097(90)91987-6  0.213
1999 Shanks N, Moore PM, Perks P, Lightman SL. Alterations in hypothalamic-pituitary-adrenal function correlated with the onset of murine SLE in MRL +/+ and lpr/lpr mice Brain, Behavior, and Immunity. 13: 348-360. PMID 10600221 DOI: 10.1006/brbi.1998.0535  0.213
1997 Kondo K, Levy A, Lightman SL. Effects of maternal iodine deficiency and thyroidectomy on basal neuroendocrine function in rat pups. The Journal of Endocrinology. 152: 423-30. PMID 9071963 DOI: 10.1677/JOE.0.1520423  0.213
1989 Moratalla R, Vallejo M, Lightman SL. In vivo stimulation of phosphoinositide metabolism in the brainstem of rats following osmotic stress. Neuroscience. 29: 391-400. PMID 2542838 DOI: 10.1016/0306-4522(89)90066-3  0.213
1987 Carter DA, Lightman SL. Oxytocin stress responses are dependent upon emotionality. Psychoneuroendocrinology. 12: 219-23. PMID 3615751 DOI: 10.1016/0306-4530(87)90007-2  0.212
2006 Kinsey-Jones JS, Li XF, Bowe JE, Lightman SL, O'Byrne KT. Corticotrophin-releasing factor type 2 receptor-mediated suppression of gonadotrophin-releasing hormone mRNA expression in GT1-7 cells. Stress (Amsterdam, Netherlands). 9: 215-22. PMID 17175507 DOI: 10.1080/10253890601040535  0.212
2001 Bauer ME, Perks P, Lightman SL, Shanks N. Restraint stress is associated with changes in glucocorticoid immunoregulation. Physiology & Behavior. 73: 525-32. PMID 11495656 DOI: 10.1016/S0031-9384(01)00503-0  0.212
1988 Eckland DJ, Lightman SL. The TSH, T4, T3 and prolactin responses to consecutive infusions of a potent and stabilized thyrotrophin releasing hormone analogue, RX77368, in man. European Journal of Clinical Investigation. 18: 405-9. PMID 2844546 DOI: 10.1111/j.1365-2362.1988.tb01031.x  0.21
2007 Tyacke RJ, Reid A, Holmes R, Grant E, Zelaya F, Reul JMHM, Lightman S, Williams S, Nutt DJ, Malizia AL. P.1.e.014 Subjective effects of acute dose of hydrocortisone in healthy volunteers European Neuropsychopharmacology. 17. DOI: 10.1016/S0924-977X(07)70404-2  0.21
2011 Spiga F, Liu Y, Aguilera G, Lightman SL. Temporal effect of adrenocorticotrophic hormone on adrenal glucocorticoid steroidogenesis: involvement of the transducer of regulated cyclic AMP-response element-binding protein activity. Journal of Neuroendocrinology. 23: 136-42. PMID 21083631 DOI: 10.1111/j.1365-2826.2010.02096.x  0.209
1989 Lightman SL, Young WS. Influence of steroids on the hypothalamic corticotropin-releasing factor and preproenkephalin mRNA responses to stress. Proceedings of the National Academy of Sciences of the United States of America. 86: 4306-10. PMID 2786213 DOI: 10.1073/PNAS.86.11.4306  0.209
2015 Zandian M, Bergh C, Ioakimidis I, Esfandiari M, Shield J, Lightman S, Leon M, Södersten P. Control of Body Weight by Eating Behavior in Children. Frontiers in Pediatrics. 3: 89. PMID 26539422 DOI: 10.3389/Fped.2015.00089  0.209
2009 Henley DE, Russell GM, Douthwaite JA, Wood SA, Buchanan F, Gibson R, Woltersdorf WW, Catterall JR, Lightman SL. Hypothalamic-pituitary-adrenal axis activation in obstructive sleep apnea: the effect of continuous positive airway pressure therapy. The Journal of Clinical Endocrinology and Metabolism. 94: 4234-42. PMID 19820009 DOI: 10.1210/jc.2009-1174  0.209
2005 Layes I, Schlotz W, Lightman S, Hellhammer D, Wüst S. Effects of chronic stress and gender on HPA axis responsivity in a pharmacologic CRH-AVP challenge test Experimental and Clinical Endocrinology & Diabetes. 113. DOI: 10.1055/s-2005-920459  0.208
2015 Spiga F, Walker JJ, Gupta R, Terry JR, Lightman SL. 60 YEARS OF NEUROENDOCRINOLOGY: Glucocorticoid dynamics: insights from mathematical, experimental and clinical studies. The Journal of Endocrinology. 226: T55-66. PMID 26148724 DOI: 10.1530/JOE-15-0132  0.207
2019 Voliotis M, Feng Li X, De Burgh R, Lass G, Lightman SL, O'Byrne KT, Tsaneva-Atanasova K. The origin of GnRH pulse generation: An integrative mathematical-experimental approach. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 31645462 DOI: 10.1523/JNEUROSCI.0828-19.2019  0.207
1992 Walker CD, Lightman SL, Steele MK, Dallman MF. Suckling is a persistent stimulus to the adrenocortical system of the rat. Endocrinology. 130: 115-25. PMID 1309321 DOI: 10.1210/endo.130.1.1309321  0.207
1986 Walsh KP, Williams TDM, Canepa-Anson R, Pitts PE, Roe P, Lightman S, Sutton R. An Animal Model for Polyuria Associated with Paroxysmal Tachycardia Clinical Science. 70: 14P-14P. DOI: 10.1042/Cs070014Pa  0.207
1993 Larsen PJ, Jessop D, Patel H, Lightman SL, Chowdrey HS. Substance P inhibits the release of anterior pituitary adrenocorticotrophin via a central mechanism involving corticotrophin-releasing factor-containing neurons in the hypothalamic paraventricular nucleus. Journal of Neuroendocrinology. 5: 99-105. PMID 7683556 DOI: 10.1111/j.1365-2826.1993.tb00368.x  0.206
1992 Meierkord H, Shorvon S, Lightman S, Trimble M. Comparison of the Effects of Frontal and Temporal Lobe Partial Seizures on Prolactin Levels Jama Neurology. 49: 225-230. PMID 1536623 DOI: 10.1001/Archneur.1992.00530270039016  0.206
2012 Kinsey-Jones JS, Grachev P, Li XF, Lin YS, Milligan SR, Lightman SL, O'Byrne KT. The inhibitory effects of neurokinin B on GnRH pulse generator frequency in the female rat. Endocrinology. 153: 307-15. PMID 22109887 DOI: 10.1210/En.2011-1641  0.205
2009 Droste SK, Collins A, Lightman SL, Linthorst AC, Reul JM. Distinct, time-dependent effects of voluntary exercise on circadian and ultradian rhythms and stress responses of free corticosterone in the rat hippocampus. Endocrinology. 150: 4170-9. PMID 19477935 DOI: 10.1210/en.2009-0402  0.205
1998 Kondo K, Harbuz MS, Levy A, Lightman SL. Inhibition of the hypothalamic-pituitary-thyroid axis in response to lipopolysaccharide is independent of changes in circulating corticosteroids. Neuroimmunomodulation. 4: 188-94. PMID 9524963 DOI: 10.1159/000097337  0.205
1984 Goedert M, Lightman SL, Emson PC. Neurotensin in the rat anterior pituitary gland: effects of endocrinological manipulations. Brain Research. 299: 160-3. PMID 6722564 DOI: 10.1016/0006-8993(84)90800-X  0.205
1988 Carter DA, Lightman SL. Temporal changes in the activity of endogenous opioid mechanisms regulating oxytocin secretion in saline-loaded rats. Neuroscience Letters. 82: 191-5. PMID 3696493 DOI: 10.1016/0304-3940(87)90128-5  0.203
2019 Lass G, Li XF, de Burgh RA, He W, Kang Y, Yeo SH, Sinnett-Smith LC, Manchishi SM, Colledge WH, Lightman SL, O'Byrne KT. Optogenetic stimulation of kisspeptin neurones within the posterodorsal medial amygdala increases LH pulse frequency in female mice. Journal of Neuroendocrinology. e12823. PMID 31872920 DOI: 10.1111/jne.12823  0.203
1991 Sarlis NJ, Chowdrey HS, Lightman SL. Oxytocin and adrenocorticotropin/corticosterone responses follow different time courses during chronic inflammatory stress in the rat Journal of Neuroimmunology. 35: 166. DOI: 10.1016/0165-5728(91)91155-6  0.203
2005 Seale JV, Wood SA, Atkinson HC, Harbuz MS, Lightman SL. Postnatal masculinization alters the HPA axis phenotype in the adult female rat. The Journal of Physiology. 563: 265-74. PMID 15611026 DOI: 10.1113/jphysiol.2004.078212  0.203
1988 Levy A, Lightman SL. Quantitative in-situ hybridization histochemistry of anterior pituitary hormone mRNA species in human pituitary adenomas. Acta Endocrinologica. 119: 397-404. PMID 3188812 DOI: 10.1530/ACTA.0.1190397  0.203
2005 Johnson PL, Hollis JH, Moratalla R, Lightman SL, Lowry CA. Acute hypercarbic gas exposure reveals functionally distinct subpopulations of serotonergic neurons in rats. Journal of Psychopharmacology (Oxford, England). 19: 327-41. PMID 15982987 DOI: 10.1177/0269881105053281  0.202
1992 Young WS, Lightman SL. Chronic stress elevates enkephalin expression in the rat paraventricular and supraoptic nuclei. Brain Research. Molecular Brain Research. 13: 111-7. PMID 1349719 DOI: 10.1016/0169-328X(92)90050-L  0.202
1990 Sett PK, Crockard HA, Powell M, Lightman S, Jacobs H. Cavernous sinus involvement in recurrent Nelson's syndrome. Acta Neurochirurgica. 104: 69-72. PMID 2386092 DOI: 10.1007/Bf01842897  0.201
1989 Levy A, Lightman SL. Effects of thyrotropin-releasing hormone and gonadotropin-releasing hormone on inositol phospholipid turnover in endocrinologically inactive pituitary adenomas and prolactinomas. The Journal of Clinical Endocrinology and Metabolism. 69: 122-6. PMID 2543687 DOI: 10.1210/JCEM-69-1-122  0.201
1985 Williams M, Canepa-Anson R, Lightman S, Marshall J, Mitsuoka T, Sutton R. Mechanisms of Polyuria and Natriuresis in Paroxysmal Tachycardia Clinical Science. 68: 68P-69P. DOI: 10.1042/Cs068068Pb  0.201
1987 Carter DA, Lightman SL. Opioid control of oxytocin secretion: evidence of distinct regulatory actions of two opiate receptor types. Life Sciences. 40: 2289-96. PMID 3035309 DOI: 10.1016/0024-3205(87)90066-X  0.2
1995 Harbuz MS, Jessop DS, Lightman SL, Chowdrey HS. The effects of restraint or hypertonic saline stress on corticotrophin-releasing factor, arginine vasopressin, and proenkephalin A mRNAs in the CFY, Sprague-Dawley and Wistar strains of rat. Brain Research. 667: 6-12. PMID 7895084 DOI: 10.1016/0006-8993(94)91707-8  0.2
2011 Conway-Campbell BL, George CL, Pooley JR, Knight DM, Norman MR, Hager GL, Lightman SL. The HSP90 molecular chaperone cycle regulates cyclical transcriptional dynamics of the glucocorticoid receptor and its coregulatory molecules CBP/p300 during ultradian ligand treatment. Molecular Endocrinology (Baltimore, Md.). 25: 944-54. PMID 21511880 DOI: 10.1210/Me.2010-0073  0.199
2019 Li XF, Adekunbi DA, Alobaid HM, Li SY, Pilot M, Lightman SL, O'Byrne KT. Role of the posterodorsal medial amygdala in predator odour stress induced puberty delay in female rats. Journal of Neuroendocrinology. e12719. PMID 30963653 DOI: 10.1111/jne.12719  0.199
2010 Lightman SL, Conway-Campbell BL. The crucial role of pulsatile activity of the HPA axis for continuous dynamic equilibration. Nature Reviews. Neuroscience. 11: 710-8. PMID 20842176 DOI: 10.1038/nrn2914  0.199
1994 Harbuz MS, Chover-Gonzalez AJ, Biswas S, Lightman SL, Chowdrey HS. Role of central catecholamines in the modulation of corticotrophin-releasing factor mRNA during adjuvant-induced arthritis in the rat. British Journal of Rheumatology. 33: 205-9. PMID 8156281 DOI: 10.1093/RHEUMATOLOGY/33.3.205  0.199
2022 Lass G, Li XF, Voliotis M, Wall E, de Burgh RA, Ivanova D, McIntyre C, Lin XH, Colledge WH, Lightman SL, Tsaneva-Atanasova K, O'Byrne KT. GnRH pulse generator frequency is modulated by kisspeptin and GABA-glutamate interactions in the posterodorsal medial amygdala in female mice. Journal of Neuroendocrinology. e13207. PMID 36305576 DOI: 10.1111/jne.13207  0.198
1987 Eckland DJ, O'Neill JH, Lightman SL. A pituitary tuberculoma. Journal of Neurology, Neurosurgery, and Psychiatry. 50: 360-1. PMID 3559619 DOI: 10.1136/jnnp.50.3.360  0.197
1992 Sarlis NJ, Chowdrey HS, Stephanou A, Lightman SL. Chronic activation of the hypothalamo-pituitary-adrenal axis and loss of circadian rhythm during adjuvant-induced arthritis in the rat. Endocrinology. 130: 1775-9. PMID 1312424 DOI: 10.1210/ENDO.130.4.1312424  0.197
2019 Jessop DS, Chowdrey HS, Lightman SL. Differential Effects of Glucocorticoids on Corticotrophin-Releasing Factor in the Rat Pituitary Neurointermediate Lobe and Median Eminence. The European Journal of Neuroscience. 2: 109-111. PMID 12106109 DOI: 10.1111/j.1460-9568.1990.tb00387.x  0.197
2023 Yoshimura M, Flynn BP, Kershaw YM, Zhao Z, Ueta Y, Lightman SL, Conway-Campbell BL. Phase-shifting the circadian glucocorticoid profile induces disordered feeding behaviour by dysregulating hypothalamic neuropeptide gene expression. Communications Biology. 6: 998. PMID 37775688 DOI: 10.1038/s42003-023-05347-3  0.197
2008 Spiga F, Harrison LR, Wood SA, MacSweeney CP, Thomson FJ, Craighead M, Grassie M, Lightman SL. Effect of the glucocorticoid receptor antagonist Org 34850 on fast and delayed feedback of corticosterone release. The Journal of Endocrinology. 196: 323-30. PMID 18252955 DOI: 10.1677/JOE-07-0503  0.197
1992 Levy A, Lightman SL. Growth hormone-releasing hormone transcripts in human pituitary adenomas. The Journal of Clinical Endocrinology and Metabolism. 74: 1474-6. PMID 1350590 DOI: 10.1210/JCEM.74.6.1350590  0.197
2013 Lightman S. The circadian regulation of emergent pituitary-adrenal pulsatility Annales D'Endocrinologie. 74: 237. DOI: 10.1016/j.ando.2013.07.007  0.197
2012 Conway-Campbell BL, Pooley JR, Hager GL, Lightman SL. Molecular dynamics of ultradian glucocorticoid receptor action. Molecular and Cellular Endocrinology. 348: 383-93. PMID 21872640 DOI: 10.1016/J.Mce.2011.08.014  0.197
2011 Mason BL, Thomas SA, Lightman SL, Pariante CM. Desipramine treatment has minimal effects on the brain accumulation of glucocorticoids in P-gp-deficient and wild-type mice. Psychoneuroendocrinology. 36: 1351-60. PMID 21481537 DOI: 10.1016/j.psyneuen.2011.03.008  0.196
1991 Lightman S, Pinter G, Yuen L, Bradbury M. Permeability Changes at Blood-Retinal Barrier in Diabetes and Effect of Aldose Reductase Inhibition Retina-the Journal of Retinal and Vitreous Diseases. 11: 266-267. DOI: 10.1097/00006982-199111020-00016  0.195
2009 Bailey JE, Phillips S, Diaper A, Rich A, Lightman S, Nutt DJ. P.4.e.006 Does the inhalation of CO2 activate neurosteroids in healthy participants? A pilot study European Neuropsychopharmacology. 19. DOI: 10.1016/S0924-977X(09)70988-5  0.195
1992 Harbuz MS, Rees RG, Eckland D, Jessop DS, Brewerton D, Lightman SL. Paradoxical responses of hypothalamic corticotropin-releasing factor (CRF) messenger ribonucleic acid (mRNA) and CRF-41 peptide and adenohypophysial proopiomelanocortin mRNA during chronic inflammatory stress. Endocrinology. 130: 1394-400. PMID 1537299 DOI: 10.1210/ENDO.130.3.1537299  0.195
2019 Kalafatakis K, Giannakeas N, Lightman SL, Charalampopoulos I, Russell GM, Tsipouras M, Tzallas A. Utilization of the Allen Gene Expression Atlas to gain further insight into glucocorticoid physiology in the adult mouse brain. Neuroscience Letters. PMID 31100428 DOI: 10.1016/j.neulet.2019.05.020  0.195
1988 Carter DA, Lightman SL. A role for the area postrema in mediating cholecystokinin-stimulated oxytocin secretion. Brain Research. 435: 327-30. PMID 2827855 DOI: 10.1016/0006-8993(87)91617-9  0.195
2016 George CL, Birnie MT, Flynn B, Kershaw Y, Lightman SL, Conway-Campbell BL. Ultradian glucocorticoid exposure directs gene-dependent and tissue-specific mRNA expression patterns in vivo. Molecular and Cellular Endocrinology. PMID 27769714 DOI: 10.1016/j.mce.2016.10.019  0.195
1998 Ueta Y, Levy A, Powell MP, Lightman SL, Kinoshita Y, Yokota A, Shibuya I, Yamashita H. Neuronal nitric oxide synthase gene expression in human pituitary tumours: a possible association with somatotroph adenomas and growth hormone-releasing hormone gene expression. Clinical Endocrinology. 49: 29-38. PMID 9797844 DOI: 10.1046/j.1365-2265.1998.00399.x  0.195
1995 Bennett PA, Levy A, Sophokleous S, Robinson ICAF, Lightman SL. Hypothalamic GH receptor gene expression in the rat: Effects of altered GH status Journal of Endocrinology. 147: 225-234. PMID 7490552 DOI: 10.1677/JOE.0.1470225  0.193
1990 Levy A, Lightman SL, Hoyland J, Mason WT. Inositol phospholipid turnover and intracellular Ca2+ responses to thyrotrophin-releasing hormone, gonadotrophin-releasing hormone and arginine vasopressin in pituitary corticotroph and somatotroph adenomas. Clinical Endocrinology. 33: 73-9. PMID 2169360 DOI: 10.1111/j.1365-2265.1990.tb00467.x  0.193
1988 Horn AM, Lightman SL. Vasopressin-stimulated turnover of phosphatidylinositol in the decentralised superior cervical ganglion of the rat. Brain Research. 455: 18-23. PMID 3416185 DOI: 10.1016/0006-8993(88)90108-4  0.193
2024 Lightman SL. Clinical Endocrinology-Time for a Reset? Journal of the Endocrine Society. 8: bvae024. PMID 38440109 DOI: 10.1210/jendso/bvae024  0.192
1995 Larsen PJ, Vrang N, Møller M, Jessop DS, Lightman SL, Chowdrey HS, Mikkelsen JD. The diurnal expression of genes encoding vasopressin and vasoactive intestinal peptide within the rat suprachiasmatic nucleus is influenced by circulating glucocorticoids. Brain Research. Molecular Brain Research. 27: 342-6. PMID 7898322 DOI: 10.1016/0169-328X(94)90021-3  0.192
2012 Johnson PL, Samuels BC, Fitz SD, Lightman SL, Lowry CA, Shekhar A. Activation of the orexin 1 receptor is a critical component of CO2-mediated anxiety and hypertension but not bradycardia. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 37: 1911-22. PMID 22453138 DOI: 10.1038/Npp.2012.38  0.192
1990 Levy A, Lightman SL, Hoyland J, Rawlings S, Mason WT. A gonadotropin-releasing hormone (GnRH) antagonist distinguishes three populations of GnRH analog-responsive cells in human and rat pituitary in vitro and produces an acute increase in intracellular Ca2+ concentration without inducing gonadotropin secretion. Molecular Endocrinology (Baltimore, Md.). 4: 678-84. PMID 2177142 DOI: 10.1210/mend-4-5-678  0.192
2009 Spiga F, Lightman SL. Dose-dependent effects of corticosterone on nuclear glucocorticoid receptors and their binding to DNA in the brain and pituitary of the rat. Brain Research. 1293: 101-7. PMID 19368803 DOI: 10.1016/j.brainres.2009.02.001  0.191
1992 Almeida OFX, Hassan AHS, Harbuz MS, Linton EA, Lightman SL. Hypothalamic corticotropin-releasing hormone and opioid peptide neurons: functional changes after adrenalectomy and/or castration Brain Research. 571: 189-198. PMID 1351778 DOI: 10.1016/0006-8993(92)90654-R  0.191
2021 Flynn BP, Birnie MT, Kershaw YM, Pauza AG, Kim S, Baek S, Rogers MF, Paterson AR, Stavreva DA, Murphy D, Hager GL, Lightman SL, Conway-Campbell BL. Corticosterone pattern-dependent glucocorticoid receptor binding and transcriptional regulation within the liver. Plos Genetics. 17: e1009737. PMID 34375333 DOI: 10.1371/journal.pgen.1009737  0.19
2015 Södersten P, Bergh C, Shield J, Lightman S. Reversible biological adaptations in obesity. The Lancet. Diabetes & Endocrinology. 3: 314. PMID 25943749 DOI: 10.1016/S2213-8587(15)00090-X  0.19
2019 Zavala E, Wedgwood KCA, Voliotis M, Tabak J, Spiga F, Lightman SL, Tsaneva-Atanasova K. Mathematical Modelling of Endocrine Systems. Trends in Endocrinology and Metabolism: Tem. PMID 30799185 DOI: 10.1016/j.tem.2019.01.008  0.19
1992 Larsen PJ, Jessop DS, Chowdrey HS, Lightman SL. Neuropeptide Y messenger ribonucleic acid in the magnocellular hypothalamo-neurohypophysial system of the rat is increased during osmotic stimulation. Neuroscience Letters. 138: 23-6. PMID 1407661 DOI: 10.1016/0304-3940(92)90463-H  0.189
2014 Orlovsky MA, Dosenko VE, Spiga F, Skibo GG, Lightman SL. Hippocampus remodeling by chronic stress accompanied by GR, proteasome and caspase-3 overexpression. Brain Research. 1593: 83-94. PMID 25285893 DOI: 10.1016/j.brainres.2014.09.059  0.189
1994 Larsen PJ, Jukes KE, Chowdrey HS, Lightman SL, Jessop DS. Neuropeptide-Y potentiates the secretion of vasopressin from the neurointermediate lobe of the rat pituitary gland. Endocrinology. 134: 1635-9. PMID 8137725 DOI: 10.1210/ENDO.134.4.8137725  0.188
2000 Lowry CA, Rodda JE, Lightman SL, Ingram CD. Corticotropin-releasing factor increases in vitro firing rates of serotonergic neurons in the rat dorsal raphe nucleus: evidence for activation of a topographically organized mesolimbocortical serotonergic system. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 7728-36. PMID 11027235  0.188
1982 Goedert M, Lightman SL, Nagy JI, Marley PD, Emson PC. Neurotensin in the rat anterior pituitary gland. Nature. 298: 163-5. PMID 7088171 DOI: 10.1038/298163A0  0.188
2001 Bauer ME, Perks P, Lightman SL, Shanks N. Are adhesion molecules involved in stress-induced changes in lymphocyte distribution? Life Sciences. 69: 1167-79. PMID 11508349 DOI: 10.1016/S0024-3205(01)01200-0  0.188
1990 Jessop DS, Chowdrey HS, Lightman SL. Inhibition of rat corticotropin-releasing factor and adrenocorticotropin secretion by an osmotic stimulus. Brain Research. 523: 1-4. PMID 2169961 DOI: 10.1016/0006-8993(90)91628-T  0.188
2019 Hazell G, Horn G, Lightman SL, Spiga F. Dynamics of ACTH-mediated regulation of gene transcription in ATC1 and ATC7 adrenal zona fasciculata cell lines. Endocrinology. PMID 30768667 DOI: 10.1210/en.2018-00840  0.188
2014 Baumeister D, Lightman SL, Pariante CM. The Interface of Stress and the HPA Axis in Behavioural Phenotypes of Mental Illness. Current Topics in Behavioral Neurosciences. 18: 13-24. PMID 24652609 DOI: 10.1007/7854_2014_304  0.186
2009 Henley DE, Leendertz JA, Russell GM, Wood SA, Taheri S, Woltersdorf WW, Lightman SL. Development of an automated blood sampling system for use in humans. Journal of Medical Engineering & Technology. 33: 199-208. PMID 19340690 DOI: 10.1080/03091900802185970  0.186
1986 Vallejo M, Lightman SL. Pressor effect of centrally administered neuropeptide Y in rats: role of sympathetic nervous system and vasopressin. Life Sciences. 38: 1859-66. PMID 3084899 DOI: 10.1016/0024-3205(86)90141-4  0.186
2016 Hoeller AA, Costa AP, Bicca MA, Matheus FC, Lach G, Spiga F, Lightman SL, Walz R, Collingridge GL, Bortolotto ZA, de Lima TC. The Role of Hippocampal NMDA Receptors in Long-Term Emotional Responses following Muscarinic Receptor Activation. Plos One. 11: e0147293. PMID 26795565 DOI: 10.1371/Journal.Pone.0147293  0.186
1993 Shi ZX, Levy A, Lightman SL. Hippocampal input to the hypothalamus inhibits thyrotrophin and thyrotrophin-releasing hormone gene expression. Neuroendocrinology. 57: 576-80. PMID 8367025 DOI: 10.1159/000126409  0.186
1986 Eckland D, Lightman S. Down regulation of the TSH response but not the prolactin response to a second infusion of the TRH analogue RX77368 Regulatory Peptides. 15: 174. DOI: 10.1016/0167-0115(86)90105-9  0.185
1994 Larsen PJ, Jessop DS, Chowdrey HS, Lightman SL, Mikkelsen JD. Chronic administration of glucocorticoids directly upregulates prepro-neuropeptide Y and Y1-receptor mRNA levels in the arcuate nucleus of the rat. Journal of Neuroendocrinology. 6: 153-9. PMID 8049712 DOI: 10.1111/j.1365-2826.1994.tb00566.x  0.185
2013 Liu Y, Smith LI, Huang V, Poon V, Coello A, Olah M, Spiga F, Lightman SL, Aguilera G. Transcriptional regulation of episodic glucocorticoid secretion. Molecular and Cellular Endocrinology. 371: 62-70. PMID 23138111 DOI: 10.1016/j.mce.2012.10.011  0.184
2023 Habets PC, Kalafatakis K, Dzyubachyk O, van der Werff SJA, Keo A, Thakrar J, Mahfouz A, Pereira AM, Russell GM, Lightman SL, Meijer OC. Transcriptional and cell type profiles of cortical brain regions showing ultradian cortisol rhythm dependent responses to emotional face stimulation. Neurobiology of Stress. 22: 100514. PMID 36660181 DOI: 10.1016/j.ynstr.2023.100514  0.184
1990 Williams TD, Lightman SL, Johnson MR, Carmichael DJ, Bannister R. Selective defect in gonadotrophin secretion in patients with autonomic failure. Clinical Endocrinology. 30: 285-92. PMID 2512037 DOI: 10.1111/j.1365-2265.1989.tb02237.x  0.184
1992 Hu SB, Tannahill LA, Biswas S, Lightman SL. Release of corticotrophin-releasing factor-41, arginine vasopressin and oxytocin from rat fetal hypothalamic cells in culture: response to activation of intracellular second messengers and to corticosteroids. The Journal of Endocrinology. 132: 57-65. PMID 1737959 DOI: 10.1677/JOE.0.1320057  0.184
2006 Wetherell MA, Crown AL, Lightman SL, Miles JN, Kaye J, Vedhara K. The four-dimensional stress test: psychological, sympathetic-adrenal-medullary, parasympathetic and hypothalamic-pituitary-adrenal responses following inhalation of 35% CO2. Psychoneuroendocrinology. 31: 736-47. PMID 16621326 DOI: 10.1016/j.psyneuen.2006.02.005  0.183
1989 Jessop DS, Eckland DJ, Todd K, Lightman SL. Osmotic regulation of hypothalamo-neurointermediate lobe corticotrophin-releasing factor-41 in the rat. The Journal of Endocrinology. 120: 119-24. PMID 2537368 DOI: 10.1677/JOE.0.1200119  0.183
2015 Gibbison B, Spiga F, Walker JJ, Russell GM, Stevenson K, Kershaw Y, Zhao Z, Henley D, Angelini GD, Lightman SL. Dynamic pituitary-adrenal interactions in response to cardiac surgery. Critical Care Medicine. 43: 791-800. PMID 25517478 DOI: 10.1097/CCM.0000000000000773  0.182
2009 Gardner KL, Hale MW, Oldfield S, Lightman SL, Plotsky PM, Lowry CA. Adverse experience during early life and adulthood interact to elevate tph2 mRNA expression in serotonergic neurons within the dorsal raphe nucleus. Neuroscience. 163: 991-1001. PMID 19647049 DOI: 10.1016/j.neuroscience.2009.07.055  0.182
2005 Kinsey-Jones JS, Li XF, Bowe JE, Brain SD, Lightman SL, O'Byrne KT. Effect of calcitonin gene-related peptide on gonadotrophin-releasing hormone mRNA expression in GT1-7 cells. Journal of Neuroendocrinology. 17: 541-4. PMID 16101891 DOI: 10.1111/J.1365-2826.2005.01341.X  0.182
2012 Biddie SC, Conway-Campbell BL, Lightman SL. Dynamic regulation of glucocorticoid signalling in health and disease. Rheumatology (Oxford, England). 51: 403-12. PMID 21891790 DOI: 10.1093/rheumatology/ker215  0.181
1992 Harbuz MS, Lightman SL. Stress and the hypothalamo-pituitary-adrenal axis: acute, chronic and immunological activation. The Journal of Endocrinology. 134: 327-39. PMID 1402543 DOI: 10.1677/JOE.0.1340327  0.181
1996 Bennett PA, Levy A, Carmignac DF, Robinson ICAF, Lightman SL. Differential regulation of the growth hormone receptor gene: Effects of dexamethasone and estradiol Endocrinology. 137: 3891-3896. PMID 8756562 DOI: 10.1210/ENDO.137.9.8756562  0.181
1993 Jessop DS, Larsen PJ, Mikkelsen JD, Lightman SL, Chowdrey HS. Effects of adrenalectomy and hypertonic saline on neuropeptide Y content in the posterior pituitary of the rat. Neuroendocrinology. 57: 416-21. PMID 8321413 DOI: 10.1159/000126387  0.181
2003 Levy A, Lightman S. Molecular defects in the pathogenesis of pituitary tumours. Frontiers in Neuroendocrinology. 24: 94-127. PMID 12763000 DOI: 10.1016/S0091-3022(03)00012-8  0.181
1990 Chowdrey HS, Jessop DS, Lightman SL. Substance P stimulates arginine vasopressin and inhibits adrenocorticotropin release in vivo in the rat. Neuroendocrinology. 52: 90-3. PMID 1697661 DOI: 10.1159/000125544  0.18
1993 Levy A, Lightman SL. The pathogenesis of pituitary adenomas. Clinical Endocrinology. 38: 559-70. PMID 8334742 DOI: 10.1111/j.1365-2265.1993.tb02136.x  0.18
1988 Eckland DJ, Todd K, Lightman SL. Immunoreactive vasopressin and oxytocin in hypothalamo-hypophysial portal blood of the Brattleboro and Long-Evans rat: effect of adrenalectomy and dexamethasone. The Journal of Endocrinology. 117: 27-34. PMID 3356957 DOI: 10.1677/JOE.0.1170027  0.179
1996 Harbuz MS, Perveen-Gill Z, Lalies MD, Jessop DS, Lightman SL, Chowdrey HS. The role of endogenous serotonin in adjuvant-induced arthritis in the rat. British Journal of Rheumatology. 35: 112-6. PMID 8612019 DOI: 10.1093/RHEUMATOLOGY/35.2.112  0.179
2013 Park SY, Walker JJ, Johnson NW, Zhao Z, Lightman SL, Spiga F. Constant light disrupts the circadian rhythm of steroidogenic proteins in the rat adrenal gland. Molecular and Cellular Endocrinology. 371: 114-23. PMID 23178164 DOI: 10.1016/J.Mce.2012.11.010  0.179
1996 Harbuz MS, Perveen-Gill Z, Lightman SL, Jessop DS. A protective role for testosterone in adjuvant-induced arthritis. British Journal of Rheumatology. 34: 1117-22. PMID 8608351 DOI: 10.1093/RHEUMATOLOGY/34.12.1117  0.179
2021 Violaris IG, Kalafatakis K, Zavala E, Tsoulos IG, Lampros T, Lightman SL, Tsipouras MG, Giannakeas N, Tzallas A, Russell GM. Modelling Hydrocortisone Pharmacokinetics on a Subcutaneous Pulsatile Infusion Replacement Strategy in Patients with Adrenocortical Insufficiency. Pharmaceutics. 13. PMID 34064165 DOI: 10.3390/pharmaceutics13060769  0.179
1986 Lightman S. Molecular approach appraised. Nature. 319: 180. PMID 3945309 DOI: 10.1038/319180A0  0.178
2011 Henley DE, Lightman SL. New insights into corticosteroid-binding globulin and glucocorticoid delivery. Neuroscience. 180: 1-8. PMID 21371536 DOI: 10.1016/j.neuroscience.2011.02.053  0.178
1986 Williams TD, Abel DC, King CM, Jelley RY, Lightman SL. Vasopressin and oxytocin responses to acute and chronic osmotic stimuli in man. The Journal of Endocrinology. 108: 163-8. PMID 3944536 DOI: 10.1677/JOE.0.1080163  0.178
1989 Lightman SL, Young WS. Corticotrophin-releasing factor, vasopressin and pro-opiomelanocortin mRNA responses to stress and opiates in the rat. The Journal of Physiology. 403: 511-23. PMID 3267021 DOI: 10.1113/jphysiol.1988.sp017261  0.178
1981 Tunstall Pedoe H, Lightman S. AN UNREPORTED SYNDROME The Lancet. 318: 1429. DOI: 10.1016/S0140-6736(81)92851-8  0.178
1985 Goedert M, Lightman SL, Mantyh PW, Hunt SP, Emson PC. Neurotensin-like immunoreactivity and neurotensin receptors in the rat hypothalamus and in the neurointermediate lobe of the pituitary gland. Brain Research. 358: 59-69. PMID 3000519 DOI: 10.1016/0006-8993(85)90948-5  0.177
2011 Wu XQ, Li XF, Ye B, Popat N, Milligan SR, Lightman SL, O'Byrne KT. Neonatal programming by immunological challenge: effects on ovarian function in the adult rat. Reproduction (Cambridge, England). 141: 241-8. PMID 21084570 DOI: 10.1530/REP-10-0252  0.177
2017 Pyc V, Spiga F, Lightman S. The effects of restricted feeding on the ultradian rhythm of corticosterone secretion and steroidogenesis in the rat adrenal Proceedings of the Nutrition Society. 76. DOI: 10.1017/S0029665117003044  0.177
1998 Conde GL, Renshaw D, Lightman SL, Harbuz MS. Serotonin depletion does not alter lipopolysaccharide-induced activation of the rat paraventricular nucleus. The Journal of Endocrinology. 156: 245-51. PMID 9518869 DOI: 10.1677/JOE.0.1560245  0.176
1985 Williams TD, Lightman SL, Bannister R. Vasopressin secretion in progressive autonomic failure: evidence for defective afferent cardiovascular pathways. Journal of Neurology, Neurosurgery, and Psychiatry. 48: 225-8. PMID 3981190 DOI: 10.1136/jnnp.48.3.225  0.176
2002 Grinevich V, Harbuz M, Ma XM, Jessop D, Tilders FJ, Lightman SL, Aguilera G. Hypothalamic pituitary adrenal axis and immune responses to endotoxin in rats with chronic adjuvant-induced arthritis. Experimental Neurology. 178: 112-23. PMID 12460613  0.175
1995 Jessop DS, Renshaw D, Lightman SL, Harbuz MS. Changes in ACTH and beta-endorphin immunoreactivity in immune tissues during a chronic inflammatory stress are not correlated with changes in corticotropin-releasing hormone and arginine vasopressin. Journal of Neuroimmunology. 60: 29-35. PMID 7642745 DOI: 10.1016/0165-5728(95)00049-8  0.174
1997 Wei T, Lightman SL. The neuroendocrine axis in patients with multiple sclerosis Brain. 120: 1067-1076. PMID 9217689 DOI: 10.1093/brain/120.6.1067  0.174
1993 Johnson MR, Carter G, Grint C, Lightman SL. Relationship between ovarian steroids, gonadotrophins and relaxin during the menstrual cycle. Acta Endocrinologica. 129: 121-5. PMID 8372595 DOI: 10.1530/ACTA.0.1290121  0.174
1984 Carter DA, Lightman SL. Substance P microinjections into the nucleus tractus solitarius elicit a pressor response in capsaicin-treated rats. Neuroscience Letters. 43: 253-7. PMID 6200807 DOI: 10.1016/0304-3940(83)90197-0  0.174
1973 Tobert JA, Slater JD, Fogelman F, Lightman SL, Kurtz AB, Payne NN. The effect in man of (+)-propranolol and racemic propranolol on renin secretion stimulated by orthostatic stress. Clinical Science. 44: 291-5. PMID 4693100 DOI: 10.1042/CS0440291  0.174
1987 Carter DA, Lightman SL. Modulation of oxytocin secretion by ascending noradrenergic pathways: sexual dimorphism in rats. Brain Research. 406: 313-6. PMID 3105813 DOI: 10.1016/0006-8993(87)90798-0  0.174
1982 Tunstall Pedoe H, Lightman S. SUCKER-DADDY (PURPURA CYCLOPS) The Lancet. 319: 632. DOI: 10.1016/S0140-6736(82)91800-1  0.173
1985 Carter DA, Lightman SL. Selective cardiovascular and neuroendocrine effects of a kappa-opioid agonist in the nucleus tractus solitarii of rats. The Journal of Physiology. 367: 363-75. PMID 2997441 DOI: 10.1113/jphysiol.1985.sp015829  0.173
2006 Kaye JM, Young TM, Mathias CJ, Watson L, Lightman SL. Neuroendocrine and behavioural responses to CO2 inhalation in central versus peripheral autonomic failure. Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society. 16: 121-9. PMID 16475017 DOI: 10.1007/s10286-006-0331-x  0.173
1993 Larsen PJ, Jessop DS, Lightman SL, Chowdrey HS. Preprotachykinin A gene expression in distinct hypothalamic and brain stem regions of the rat is affected by a chronic osmotic stimulus: a combined immunohistochemical and in situ hybridization histochemistry study. Brain Research Bulletin. 30: 535-45. PMID 7681354 DOI: 10.1016/0361-9230(93)90080-U  0.173
1988 Hodges JK, Green DI, Cottingham PG, Sauer MJ, Edwards C, Lightman SL. Induction of luteal regression in the marmoset monkey (Callithrix jacchus) by a gonadotrophin-releasing hormone antagonist and the effects on subsequent follicular development. Journal of Reproduction and Fertility. 82: 743-52. PMID 3129559 DOI: 10.1530/JRF.0.0820743  0.172
1992 Larsen PJ, Jessop DS, Chowdrey HS, Mikkelsen JD, Lightman SL. Osmotic regulation of substance P and neurokinin A peptide content and substance P binding sites in distinct hypothalamic nuclei of the rat. Peptides. 13: 705-12. PMID 1279630 DOI: 10.1016/0196-9781(92)90176-4  0.171
1994 Johnson MR, Chowdrey HS, Thomas F, Grint C, Lightman SL. Pharmacokinetics and efficacy of the long-acting somatostatin analogue somatuline in acromegaly. European Journal of Endocrinology. 130: 229-34. PMID 7908838 DOI: 10.1530/EJE.0.1300229  0.171
1990 Jessop D, Sidhu R, Lightman SL. Osmotic regulation of methionine enkephalin in the posterior pituitary of the rat. Brain Research. 516: 41-5. PMID 2364280 DOI: 10.1016/0006-8993(90)90895-I  0.171
1984 Marley PD, Lightman SL, Forsling ML, Todd K, Goedert M, Rehfeld JF, Emson PC. Localization and actions of cholecystokinin in the rat pituitary neurointermediate lobe. Endocrinology. 114: 1902-11. PMID 6325136 DOI: 10.1210/Endo-114-5-1902  0.169
1987 Lightman S, McDONALD WI, Bird AC, Francis DA, Hoskins A, Batcholer JR, Halliday AM. Retinal Venous Sheathing In Optic Neuritis Brain. 110: 405-414. PMID 3567529 DOI: 10.1093/Brain/110.2.405  0.169
1986 Williams TD, Da Costa D, Mathias CJ, Bannister R, Lightman SL. Pressor effect of arginine vasopressin in progressive autonomic failure. Clinical Science (London, England : 1979). 71: 173-8. PMID 3720194 DOI: 10.1042/CS0710173  0.169
1986 Carter DA, Vallejo M, Lightman SL. Cardiovascular effects of neuropeptide Y in the nucleus tractus solitarius of rats: relationship with noradrenaline and vasopressin. Peptides. 6: 421-5. PMID 3840887 DOI: 10.1016/0196-9781(85)90107-X  0.169
1990 Sanders G, Freilicher J, Lightman SL. Psychological stress of exposure to uncontrollable noise increases plasma oxytocin in high emotionality women. Psychoneuroendocrinology. 15: 47-58. PMID 2367615 DOI: 10.1016/0306-4530(90)90046-C  0.169
1985 Williams TD, Carter DA, Lightman SL. Sexual dimorphism in the posterior pituitary response to stress in the rat. Endocrinology. 116: 738-40. PMID 3967625 DOI: 10.1210/ENDO-116-2-738  0.168
1987 Lightman S, Everitt B. Points: Public not private property Bmj. 294: 1615-1615. DOI: 10.1136/Bmj.294.6587.1615-D  0.168
1997 Jessop DS, Harbuz MS, Snelson CL, Dayan CM, Lightman SL. An antisense oligodeoxynucleotide complementary to corticotropin-releasing hormone mRNA inhibits rat splenocyte proliferation in vitro. Journal of Neuroimmunology. 75: 135-40. PMID 9143246 DOI: 10.1016/S0165-5728(97)00011-8  0.168
1990 Seckl JR, Johnson MR, Lightman SL. Vasopressin and oxytocin responses to hypertonic saline infusion: effect of the opioid antagonist naloxone. Clinical Endocrinology. 30: 513-8. PMID 2605788 DOI: 10.1111/j.1365-2265.1989.tb01422.x  0.168
2005 Gardner KL, Thrivikraman KV, Lightman SL, Plotsky PM, Lowry CA. Early life experience alters behavior during social defeat: focus on serotonergic systems. Neuroscience. 136: 181-91. PMID 16182451 DOI: 10.1016/j.neuroscience.2005.07.042  0.167
1990 Chowdrey HS, Lightman SL. Neuroendocrine control of blood tonicity and volume. Bailliere's Clinical Endocrinology and Metabolism. 3: 229-47. PMID 2576517 DOI: 10.1016/S0950-351X(89)80004-7  0.167
1994 Lightman SL. How does the hypothalamus respond to stress? Seminars in Neuroscience. 6: 215-219. DOI: 10.1006/SMNS.1994.1028  0.167
1995 Chen ZP, Kratzmeier M, Levy A, McArdle CA, Poch A, Day A, Mukhopadhyay AK, Lightman SL. Evidence for a role of pituitary ATP receptors in the regulation of pituitary function. Proceedings of the National Academy of Sciences of the United States of America. 92: 5219-23. PMID 7761477 DOI: 10.1073/PNAS.92.11.5219  0.167
1989 Levy A, Lightman SL. Quantitative in-situ hybridization histochemistry studies on growth hormone (GH) gene expression in acromegalic somatotrophs: effects of somatostatin, GH-releasing factor and cortisol. Journal of Molecular Endocrinology. 1: 19-26. PMID 2908268 DOI: 10.1677/JME.0.0010019  0.166
1985 Stoneham MD, Everitt BJ, Hansen S, Lightman SL, Todd K. Oxytocin and sexual behaviour in the male rat and rabbit. The Journal of Endocrinology. 107: 97-106. PMID 4045356 DOI: 10.1677/JOE.0.1070097  0.166
1987 Vallejo M, Lightman SL. Evidence for a functional relationship between noradrenaline and neurohypophyseal peptides in the brainstem of rats. Brain Research. 422: 295-302. PMID 3676790 DOI: 10.1016/0006-8993(87)90936-X  0.166
1998 Nolan LA, Kavanagh E, Lightman SL, Levy A. Anterior pituitary cell population control: basal cell turnover and the effects of adrenalectomy and dexamethasone treatment. Journal of Neuroendocrinology. 10: 207-15. PMID 9576609 DOI: 10.1046/j.1365-2826.1998.00191.x  0.166
1988 Vallejo M, Lightman S, Marshall I. Central cardiovascular effects of calcitonin gene-related peptide: interaction with noradrenaline in the nucleus tractus solitarius of rats. Experimental Brain Research. 70: 221-4. PMID 3261256 DOI: 10.1007/BF00271863  0.166
1972 Stanfcrd JL, Brook AS, Shepherd M, Bannerman C, Todd PJ, Aspinall JS, Knight N, Norris RM, Webb P, Smith DW, Rutter D, Unsworth P, Cheetham D, Dodman S, Peskett S, ... ... Lightman S, et al. Erasures from the “Register” British Medical Journal. 4: 423-424. DOI: 10.1136/Bmj.4.5837.423-A  0.165
1992 Eckland DJ, Harbuz MS, Jessop DS, Lightman SL. Corticotrophin-releasing factor and arginine vasopressin in the hypothalamo-hypophyseal portal blood of rats following high-dose glucocorticoid treatment and withdrawal. Brain Research. 568: 311-3. PMID 1814575 DOI: 10.1016/0006-8993(91)91416-X  0.164
1987 Guiloff RJ, Eckland DJ, Demaine C, Hoare RC, MacRae KD, Lightman SL. Controlled acute trial of a thyrotrophin releasing hormone analogue (RX77368) in motor neuron disease. Journal of Neurology, Neurosurgery, and Psychiatry. 50: 1359-70. PMID 3119776 DOI: 10.1136/jnnp.50.10.1359  0.164
2023 Birnie MT, Claydon MDB, Troy O, Flynn BP, Yoshimura M, Kershaw YM, Zhao Z, Demski-Allen RCR, Barker GRI, Warburton EC, Bortolotto ZA, Lightman SL, Conway-Campbell BL. Circadian regulation of hippocampal function is disrupted with corticosteroid treatment. Proceedings of the National Academy of Sciences of the United States of America. 120: e2211996120. PMID 37023133 DOI: 10.1073/pnas.2211996120  0.163
2001 Rook G, Baker R, Walker B, Honour J, Jessop D, Hernandez-Pando R, Arriaga K, Shaw R, Zumla A, Lightman S. Local regulation of glucocorticoid activity in sites of inflammation. Insights from the study of tuberculosis. Annals of the New York Academy of Sciences. 917: 913-22. PMID 11268421 DOI: 10.1111/j.1749-6632.2000.tb05457.x  0.163
2016 Kalafatakis K, Russell GM, Harmer CJ, Munafo MR, Marchant N, Wilson A, Brooks JC, Thai NJ, Ferguson SG, Stevenson K, Durant C, Schmidt K, Lightman SL. Effects of the pattern of glucocorticoid replacement on neural processing, emotional reactivity and well-being in healthy male individuals: study protocol for a randomised controlled trial. Trials. 17: 44. PMID 26801980 DOI: 10.1186/s13063-016-1159-x  0.163
1994 Chowdrey HS, Lightman SL, Harbuz MS, Larsen PJ, Jessop DS. Contents of corticotropin-releasing hormone and arginine vasopressin immunoreactivity in the spleen and thymus during a chronic inflammatory stress. Journal of Neuroimmunology. 53: 17-21. PMID 8051295 DOI: 10.1016/0165-5728(94)90059-0  0.163
2002 Lightman SL, Insel TR, Ingram CD. New genomic avenues in behavioural neuroendocrinology. The European Journal of Neuroscience. 16: 369-72. PMID 12193175 DOI: 10.1046/j.1460-9568.2002.02082.x  0.162
2016 Fitzsimons CP, Herbert J, Schouten M, Meijer OC, Lucassen PJ, Lightman S. Circadian and Ultradian Glucocorticoid Rhythmicity: Implications for the Effects of Glucocorticoids on Neural Stem Cells and Adult Hippocampal Neurogenesis. Frontiers in Neuroendocrinology. PMID 27234350 DOI: 10.1016/J.Yfrne.2016.05.001  0.162
2013 Whitehead G, Jo J, Hogg EL, Piers T, Kim DH, Seaton G, Seok H, Bru-Mercier G, Son GH, Regan P, Hildebrandt L, Waite E, Kim BC, Kerrigan TL, Kim K, ... ... Lightman SL, et al. Acute stress causes rapid synaptic insertion of Ca2+ -permeable AMPA receptors to facilitate long-term potentiation in the hippocampus. Brain : a Journal of Neurology. 136: 3753-65. PMID 24271563 DOI: 10.1093/Brain/Awt293  0.162
2010 Perogamvros I, Underhill C, Henley DE, Hadfield KD, Newman WG, Ray DW, Lightman SL, Hammond GL, Trainer PJ. Novel corticosteroid-binding globulin variant that lacks steroid binding activity. The Journal of Clinical Endocrinology and Metabolism. 95: E142-50. PMID 20610591 DOI: 10.1210/jc.2010-0746  0.162
2006 Spiga F, Lightman SL, Shekhar A, Lowry CA. Injections of urocortin 1 into the basolateral amygdala induce anxiety-like behavior and c-Fos expression in brainstem serotonergic neurons. Neuroscience. 138: 1265-76. PMID 16488545 DOI: 10.1016/J.Neuroscience.2005.12.051  0.161
2009 Gardner KL, Hale MW, Lightman SL, Plotsky PM, Lowry CA. Adverse early life experience and social stress during adulthood interact to increase serotonin transporter mRNA expression. Brain Research. 1305: 47-63. PMID 19781533 DOI: 10.1016/j.brainres.2009.09.065  0.161
1992 Levy A, Matovelle MC, Lightman SL, Young WS. The effects of pituitary stalk transection, hypophysectomy and thyroid hormone status on insulin-like growth factor 2-, growth hormone releasing hormone-, and somatostatin mRNA prevalence in rat brain. Brain Research. 579: 1-7. PMID 1352477 DOI: 10.1016/0006-8993(92)90735-R  0.161
2009 Henley DE, Buchanan F, Gibson R, Douthwaite JA, Wood SA, Woltersdorf WW, Catterall JR, Lightman SL. Plasma apelin levels in obstructive sleep apnea and the effect of continuous positive airway pressure therapy. The Journal of Endocrinology. 203: 181-8. PMID 19643928 DOI: 10.1677/JOE-09-0245  0.161
2015 Li XF, Hu MH, Hanley BP, Lin YS, Poston L, Lightman SL, O'Byrne KT. The Posterodorsal Medial Amygdala Regulates the Timing of Puberty Onset in Female Rats. Endocrinology. en20151366. PMID 26252061 DOI: 10.1210/En.2015-1366  0.161
2012 Makara GB, Harbuz MS, Coventry TL, Jessop DS, Zelena D, Lightman SL. The effect of hypothalamic lesions on hypothalamo-pituitary-adrenal axis activity and inflammation in adjuvant-induced arthritis. Stress (Amsterdam, Netherlands). 4: 25-37. PMID 22432125 DOI: 10.3109/10253890109001141  0.161
2002 Bauer ME, Papadopoulos A, Poon L, Perks P, Lightman SL, Checkley S, Shanks N. Dexamethasone-induced effects on lymphocyte distribution and expression of adhesion molecules in treatment-resistant depression. Psychiatry Research. 113: 1-15. PMID 12467941 DOI: 10.1016/S0165-1781(02)00243-3  0.16
2020 Pooley JR, Rivers CA, Kilcooley MT, Paul SN, Cavga AD, Kershaw YM, Muratcioglu S, Gursoy A, Keskin O, Lightman SL. Beyond the heterodimer model for mineralocorticoid and glucocorticoid receptor interactions in nuclei and at DNA. Plos One. 15: e0227520. PMID 31923266 DOI: 10.1371/Journal.Pone.0227520  0.16
2005 Crown A, Lightman S. Why is the management of glucocorticoid deficiency still controversial: a review of the literature. Clinical Endocrinology. 63: 483-92. PMID 16268798 DOI: 10.1111/j.1365-2265.2005.02320.x  0.16
1984 Lightman SL, Todd K, Everitt BJ. Ascending noradrenergic projections from the brainstem: Evidence for a major role in the regulation of blood pressure and vasopressin secretion Experimental Brain Research. 55: 145-151. PMID 6745345 DOI: 10.1007/BF00240508  0.16
1994 Harbuz M, Chowdrey H, Lightman S, Larsen P, Jessop D. Corticotrophin-releasing factor and arginne vasopressin immunoreactivity in the spleen and thymus during a chronic inflammatory stress Journal of Neuroimmunology. 54: 166. DOI: 10.1016/0165-5728(94)90348-4  0.16
1988 Seckl JR, Lightman SL. Effect of naloxone on oxytocin and vasopressin release during vaginocervical stimulation in the goat. The Journal of Endocrinology. 115: 317-22. PMID 3437251 DOI: 10.1677/JOE.0.1150317  0.159
1987 Seckl JR, Dunger DB, Lightman SL. Neurohypophyseal peptide function during early postoperative diabetes insipidus. Brain : a Journal of Neurology. 737-46. PMID 3580832 DOI: 10.1093/BRAIN/110.3.737  0.158
2021 Fudulu DP, Horn G, Hazell G, Lefrançois-Martinez AM, Martinez A, Angelini GD, Lightman SL, Spiga F. Co-culture of monocytes and zona fasciculata adrenal cells: an in vitro model to study the immune-adrenal cross-talk. Molecular and Cellular Endocrinology. 111195. PMID 33571577 DOI: 10.1016/j.mce.2021.111195  0.158
2000 Mahajan T, Lightman SL. A simple test for growth hormone deficiency in adults. The Journal of Clinical Endocrinology and Metabolism. 85: 1473-6. PMID 10770184 DOI: 10.1210/jcem.85.4.6545  0.158
2019 Gibbison B, Keenan DM, Roelfsema F, Evans J, Phillips K, Rogers CA, Angelini GD, Lightman SL. Dynamic pituitary-adrenal interactions in the critically ill after cardiac surgery. The Journal of Clinical Endocrinology and Metabolism. PMID 31738827 DOI: 10.1210/Clinem/Dgz206  0.158
1990 Williams TD, Travill CM, Noble MI, Drake-Holland AJ, Chalmers J, Jeffery CD, Sutton R, Lightman SL. Mechanisms of impaired excretion of a fluid load after cardiac denervation in dogs. The American Journal of Physiology. 259: R70-5. PMID 2142861 DOI: 10.1152/ajpregu.1990.259.1.R70  0.158
1998 Ueta Y, Levy A, Lightman SL, Hara Y, Serino R, Nomura M, Shibuya I, Hattori Y, Yamashita H. Hypovolemia upregulates the expression of neuronal nitric oxide synthase gene in the paraventricular and supraoptic nuclei of rats. Brain Research. 790: 25-32. PMID 9593810 DOI: 10.1016/S0006-8993(97)01531-X  0.158
1991 Blake NG, Eckland DJ, Foster OJ, Lightman SL. Inhibition of hypothalamic thyrotropin-releasing hormone messenger ribonucleic acid during food deprivation. Endocrinology. 129: 2714-8. PMID 1935800 DOI: 10.1210/ENDO-129-5-2714  0.158
2016 Lopes MW, Leal RB, Guarnieri R, Schwarzbold ML, Hoeller A, Diaz AP, Boos GL, Lin K, Linhares MN, Nunes JC, Quevedo J, Bortolotto ZA, Markowitsch HJ, Lightman SL, Walz R. A single high dose of dexamethasone affects the phosphorylation state of glutamate AMPA receptors in the human limbic system. Translational Psychiatry. 6: e986. PMID 27959333 DOI: 10.1038/Tp.2016.251  0.158
1996 Ueta Y, Levy A, Chowdrey HS, Lightman SL. Inhibition of hypothalamic nitric oxide synthase gene expression in the rat paraventricular nucleus by food deprivation is independent of serotonin depletion. Journal of Neuroendocrinology. 7: 861-5. PMID 8748123 DOI: 10.1111/j.1365-2826.1995.tb00727.x  0.157
2003 Bauer ME, Papadopoulos A, Poon L, Perks P, Lightman SL, Checkley S, Shanks N. Altered glucocorticoid immunoregulation in treatment resistant depression. Psychoneuroendocrinology. 28: 49-65. PMID 12445836 DOI: 10.1016/S0306-4530(02)00009-4  0.157
1987 Carter DA, Lightman SL. Comparative distribution and cardiovascular actions of substance P and substance K within the nucleus tractus solitarius of rats. Neuropeptides. 8: 295-304. PMID 2434876 DOI: 10.1016/0143-4179(86)90001-6  0.157
2014 Lightman SL, George CL. Steroid hormones in 2013: Glucocorticoids: timing, binding and environment. Nature Reviews. Endocrinology. 10: 71-2. PMID 24366119 DOI: 10.1038/nrendo.2013.257  0.157
1987 Poole CJ, Williams TD, Lightman SL, Frankel HL. Neuroendocrine control of vasopressin secretion and its effect on blood pressure in subjects with spinal cord transection. Brain : a Journal of Neurology. 727-35. PMID 3580831 DOI: 10.1093/BRAIN/110.3.727  0.157
1995 Ueta Y, Levy A, Chowdrey HS, Lightman SL. Hypothalamic nitric oxide synthase gene expression is regulated by thyroid hormones. Endocrinology. 136: 4182-7. PMID 7545100 DOI: 10.1210/ENDO.136.10.7545100  0.157
2007 Ayres BE, Thomas F, Zacharowski K, Lightman SL, Persad RA. The stress response in laparoscopic urological surgery. Bju International. 99: 1331-2. PMID 17419702 DOI: 10.1111/j.1464-410X.2007.06847.x  0.157
1987 Poole CJ, Carter DA, Vallejo M, Lightman SL. Atrial natriuretic factor inhibits the stimulated in-vivo and in-vitro release of vasopressin and oxytocin in the rat. The Journal of Endocrinology. 112: 97-102. PMID 2950195 DOI: 10.1677/JOE.0.1120097  0.157
1991 Harbuz M, Russell JA, Sumner BE, Kawata M, Lightman SL. Rapid changes in the content of proenkephalin A and corticotrophin releasing hormone mRNAs in the paraventricular nucleus during morphine withdrawal in urethane-anaesthetized rats. Brain Research. Molecular Brain Research. 9: 285-91. PMID 1645431 DOI: 10.1016/0169-328X(91)90074-8  0.156
2005 Henry BA, Lightman SL, Lowry CA. Distribution of corticotropin-releasing factor binding protein-immunoreactivity in the rat hypothalamus: association with corticotropin-releasing factor-, urocortin 1- and vimentin-immunoreactive fibres. Journal of Neuroendocrinology. 17: 135-44. PMID 15796765 DOI: 10.1111/j.1365-2826.2005.01274.x  0.155
2014 Russell GM, Lightman SL. Can side effects of steroid treatments be minimized by the temporal aspects of delivery method? Expert Opinion On Drug Safety. 13: 1501-13. PMID 25260535 DOI: 10.1517/14740338.2014.965141  0.155
2004 Grundy PL, Patel N, Harbuz MS, Lightman SL, Sharples PM. Adrenalectomy further suppresses the NT-3 mRNA response to traumatic brain injury but this effect is not reversed with corticosterone. Brain Research. Molecular Brain Research. 120: 188-92. PMID 14741409  0.154
1984 Hanley MR, Benton HP, Lightman SL, Todd K, Bone EA, Fretten P, Palmer S, Kirk CJ, Michell RH. A vasopressin-like peptide in the mammalian sympathetic nervous system. Nature. 309: 258-61. PMID 6717603 DOI: 10.1038/309258A0  0.154
2002 Cotter PA, Mulligan OF, Landau S, Papadopoulos A, Lightman SL, Checkley SA. Vasoconstrictor response to topical beclomethasone in major depression. Psychoneuroendocrinology. 27: 475-87. PMID 11912000 DOI: 10.1016/S0306-4530(01)00065-8  0.154
1997 Harbuz MS, Chover-Gonzalez AJ, Conde GL, Renshaw D, Lightman SL, Jessop DS. Interleukin-1 beta-induced effects on plasma oxytocin and arginine vasopressin: role of adrenal steroids and route of administration. Neuroimmunomodulation. 3: 358-63. PMID 9266547 DOI: 10.1159/000097296  0.154
2007 Lowry CA, Hollis JH, de Vries A, Pan B, Brunet LR, Hunt JR, Paton JF, van Kampen E, Knight DM, Evans AK, Rook GA, Lightman SL. Identification of an immune-responsive mesolimbocortical serotonergic system: potential role in regulation of emotional behavior. Neuroscience. 146: 756-72. PMID 17367941 DOI: 10.1016/J.Neuroscience.2007.01.067  0.154
1987 Hughes AM, Everitt BJ, Lightman SL, Todd K. Oxytocin in the central nervous system and sexual behaviour in male rats. Brain Research. 414: 133-7. PMID 3620914 DOI: 10.1016/0006-8993(87)91333-3  0.154
1994 Chover-Gonzalez AJ, Lightman SL, Harbuz MS. An investigation of the effects of interleukin-1 beta on plasma arginine vasopressin in the rat: role of adrenal steroids. The Journal of Endocrinology. 142: 361-6. PMID 7931009 DOI: 10.1677/JOE.0.1420361  0.154
1985 Linsell CR, Lightman SL, Mullen PE, Brown MJ, Causon RC. Circadian rhythms of epinephrine and norepinephrine in man. The Journal of Clinical Endocrinology and Metabolism. 60: 1210-5. PMID 3998066 DOI: 10.1210/Jcem-60-6-1210  0.154
1988 Eckland DJ, Todd K, Jessop DS, Biswas S, Lightman SL. Differential effects of hypothalamic catecholamine depletion on the release of arginine vasopressin and CRF-41 into hypothalamo-hypophyseal portal blood. Neuroscience Letters. 90: 292-6. PMID 3138577 DOI: 10.1016/0304-3940(88)90204-2  0.153
2005 Johnson PL, Moratalla R, Lightman SL, Lowry CA. Are tuberomammillary histaminergic neurons involved in CO2-mediated arousal? Experimental Neurology. 193: 228-33. PMID 15817281 DOI: 10.1016/J.Expneurol.2004.11.022  0.153
2022 Nishimura H, Yoshimura M, Shimizu M, Sanada K, Sonoda S, Nishimura K, Baba K, Ikeda N, Motojima Y, Maruyama T, Nonaka Y, Baba R, Onaka T, Horishita T, Morimoto H, ... ... Lightman S, et al. Endogenous oxytocin exerts anti-nociceptive and anti-inflammatory effects in rats. Communications Biology. 5: 907. PMID 36064593 DOI: 10.1038/s42003-022-03879-8  0.153
1994 Lightman SL, Harbuz MS, Knight RA, Chowdrey HS. CRF mRNA in normal and stress conditions. Annals of the New York Academy of Sciences. 697: 28-38. PMID 8257019 DOI: 10.1111/j.1749-6632.1993.tb49920.x  0.153
1992 Blake NG, Johnson MR, Eckland DJ, Foster OJ, Lightman SL. Effect of food deprivation and altered thyroid status on the hypothalamic-pituitary-thyroid axis in the rat. The Journal of Endocrinology. 133: 183-8. PMID 1613420 DOI: 10.1677/JOE.0.1330183  0.152
1988 Parmar H, Rustin G, Lightman SL, Phillips RH, Hanham IW, Schally AV. Response to D-Trp-6-luteinising hormone releasing hormone (Decapeptyl) microcapsules in advanced ovarian cancer. British Medical Journal (Clinical Research Ed.). 296: 1229. PMID 2968130 DOI: 10.1136/Bmj.296.6631.1229  0.152
1989 Laycock JF, Lightman SL. Cardiovascular interactions between vasopressin, angiotensin and noradrenaline in the Brattleboro rat. British Journal of Pharmacology. 96: 347-55. PMID 2493961 DOI: 10.1111/j.1476-5381.1989.tb11824.x  0.152
2021 Sanada K, Yoshimura M, Ikeda N, Baba K, Nishimura H, Nishimura K, Nonaka Y, Maruyama T, Miyamoto T, Mori M, Conway-Campbell B, Lightman S, Kataoka M, Ueta Y. Chemogenetic activation of endogenous arginine vasopressin exerts anorexigenic effects via central nesfatin-1/NucB2 pathway. The Journal of Physiological Sciences : Jps. 71: 18. PMID 34134629 DOI: 10.1186/s12576-021-00802-4  0.152
1990 Murphy MR, Checkley SA, Seckl JR, Lightman SL. Naloxone inhibits oxytocin release at orgasm in man. The Journal of Clinical Endocrinology and Metabolism. 71: 1056-8. PMID 2401707 DOI: 10.1210/JCEM-71-4-1056  0.152
2017 Adekunbi DA, Li XF, Li S, Adegoke OA, Iranloye BO, Morakinyo AO, Lightman SL, Taylor PD, Poston L, O'Byrne KT. Role of amygdala kisspeptin in pubertal timing in female rats. Plos One. 12: e0183596. PMID 28846730 DOI: 10.1371/Journal.Pone.0183596  0.151
1993 Knight RA, Stephanou A, Sarlis NJ, Chowdrey HS, Lightman SL. Direct stimulation of the pituitary by transfer of activated leucocytes. Journal of Neuroendocrinology. 5: 229-31. PMID 8391362 DOI: 10.1111/j.1365-2826.1993.tb00477.x  0.151
1990 Levy A, Lightman SL. Relationship between somatostatin and growth hormone messenger ribonucleic acid in human pituitary adenomas: an in-situ hybridization histochemistry study. Clinical Endocrinology. 32: 661-8. PMID 1973086 DOI: 10.1111/j.1365-2265.1990.tb00910.x  0.151
2015 Hao K, Kong FP, Gao YQ, Tang JW, Chen J, Evans AM, Lightman SL, Chen XQ, Du JZ. Inactivation of corticotropin-releasing hormone-induced insulinotropic role by high-altitude hypoxia. Diabetes. 64: 785-95. PMID 25277397 DOI: 10.2337/db14-0500  0.15
2001 Jessop DS, Dallman MF, Fleming D, Lightman SL. Resistance to glucocorticoid feedback in obesity. The Journal of Clinical Endocrinology and Metabolism. 86: 4109-14. PMID 11549634 DOI: 10.1210/jcem.86.9.7826  0.15
2020 Gibbison B, Keenan DM, Roelfsema F, Evans J, Phillips K, Rogers CA, Angelini GD, Lightman SL. Response to Letter to the Editor from Richard Dorin: Dynamic pituitary-adrenal interactions in the critically ill after cardiac surgery. The Journal of Clinical Endocrinology and Metabolism. PMID 32609339 DOI: 10.1210/Clinem/Dgaa422  0.15
2006 Hollis JH, Evans AK, Bruce KP, Lightman SL, Lowry CA. Lipopolysaccharide has indomethacin-sensitive actions on Fos expression in topographically organized subpopulations of serotonergic neurons. Brain, Behavior, and Immunity. 20: 569-77. PMID 16554144 DOI: 10.1016/J.Bbi.2006.01.006  0.15
2017 Kalafatakis K, Russell G, Harmer C, Munafo M, Marchant N, Thakrar J, Murphy P, Thai N, Wilson A, Brooks J, Lightman S. Deviations from the physiological, ultradian glucocorticoid rhythm are accompanied by altered behavioural and fMRI responses to emotional stimulation European Neuropsychopharmacology. 27: S702-S703. DOI: 10.1016/S0924-977X(17)31301-9  0.15
1993 Hu SB, Tannahill LA, Lightman SL. Dexamethasone and aldosterone modulate corticotropin-releasing factor-41 release from cultured rat fetal hypothalamic cells through type II and type I corticosteroid receptors respectively. Neuroendocrinology. 56: 591-6. PMID 1475016 DOI: 10.1159/000126278  0.15
1988 Williams TD, Walsh KP, Lightman SL, Sutton R. Atrial natriuretic peptide inhibits postural release of renin and vasopressin in humans. The American Journal of Physiology. 255: R368-72. PMID 2970806 DOI: 10.1152/AJPREGU.1988.255.3.R368  0.149
1993 Shi ZX, Levy A, Lightman SL. The effect of dietary protein on thyrotropin-releasing hormone and thyrotropin gene expression. Brain Research. 606: 1-4. PMID 8461989 DOI: 10.1016/0006-8993(93)91561-6  0.149
2000 Condé GL, Renshaw D, Zubelewicz B, Lightman SL, Harbuz MS. Central LPS-induced c-fos expression in the PVN and the A1/A2 brainstem noradrenergic cell groups is altered by adrenalectomy. Neuroendocrinology. 70: 175-85. PMID 10516480 DOI: 10.1159/000054474  0.149
1981 Lightman SL, Forsling ML. The effect of the methionine enkephalin analogue DAMME on the vasopression response to tilt in man. Clinical Science (London, England : 1979). 59: 501-3. PMID 7438715 DOI: 10.1042/CS0590501  0.148
2017 Stubbs FE, Birnie MT, Biddie SC, Lightman SL, Conway-Campbell BL. SKOV3 cells containing a truncated ARID1a protein have a restricted genome-wide response to glucocorticoids. Molecular and Cellular Endocrinology. PMID 28942102 DOI: 10.1016/j.mce.2017.09.018  0.148
1985 Lightman SL, Unwin RJ, Graham K, Dimaline R, McGarrick G. Vasoactive intestinal polypeptide stimulation of prolactin release and renin activity in normal man and patients with hyperprolactinaemia: effects of pretreatment with bromocriptine and dexamethazone. European Journal of Clinical Investigation. 14: 444-8. PMID 6441721 DOI: 10.1111/j.1365-2362.1984.tb01211.x  0.148
1987 Seckl JR, Lightman SL. Diurnal rhythm of vasopressin but not of oxytocin in the cerebrospinal fluid of the goat: lack of association with plasma cortisol rhythm. The Journal of Endocrinology. 114: 477-82. PMID 3668436 DOI: 10.1677/JOE.0.1140477  0.148
2012 Hazell GG, Hindmarch CC, Pope GR, Roper JA, Lightman SL, Murphy D, O'Carroll AM, Lolait SJ. G protein-coupled receptors in the hypothalamic paraventricular and supraoptic nuclei--serpentine gateways to neuroendocrine homeostasis. Frontiers in Neuroendocrinology. 33: 45-66. PMID 21802439 DOI: 10.1016/J.Yfrne.2011.07.002  0.148
2019 Bhake R, Russell GM, Kershaw Y, Stevens K, Zaccardi F, Warburton VEC, Linthorst ACE, Lightman SL. Continuous Free Cortisol Profiles in Healthy Men - Validation of Microdialysis Method. The Journal of Clinical Endocrinology and Metabolism. PMID 31529059 DOI: 10.1210/clinem/dgz002  0.147
1987 Poole C, Carter D, Lightman S. Centrally Administered Atrial Natriuretic Factor Inhibits the Arginine Vasopressin and Oxytocin Response to Haemorrhage in Conscious Rats Clinical Science. 72: 17P-17P. DOI: 10.1042/cs072017pa  0.147
2006 Atkinson H, Wood S, Kershaw Y, Castrique E, Lightman S. Rapid effects of the mineralocorticoid receptor antagonist canrenoate on basal activity of the HPA axis in the rat Frontiers in Neuroendocrinology. 27: 49-50. DOI: 10.1016/j.yfrne.2006.03.101  0.146
1991 Knight R, Stephanou A, Lightman SL. Expression in human lymphocytes of a peptide and mRNA related to growth hormone-releasing hormone Journal of Neuroimmunology. 35: 167. DOI: 10.1016/0165-5728(91)91157-8  0.146
2012 Turner-Cobb JM, Jessop DS, Lightman SL. Effects of childhood stress: Hardwired or reversible? Biologist. 59: 31-35.  0.146
1983 Puritz R, Lightman SL, Wilcox CS, Forsling M, Bannister R. Blood pressure and vasopressin in progressive autonomic failure. Response to postural stimulation, L-dopa and naloxone. Brain : a Journal of Neurology. 503-11. PMID 6850280 DOI: 10.1093/BRAIN/106.2.503  0.145
1993 Sarlis NJ, Stephanou A, Knight RA, Lightman SL, Chowdrey HS. Effects of glucocorticoids and chronic inflammatory stress upon anterior pituitary interleukin-6 mRNA expression in the rat. British Journal of Rheumatology. 32: 653-7. PMID 8348265 DOI: 10.1093/RHEUMATOLOGY/32.8.653  0.145
1989 Williams T, Dent M, Poole C, Lightman S. Pressor Effect of Arginine Vasopressin Following Atropine Administration in Man Clinical Science. 77: 13P-13P. DOI: 10.1042/CS077013PB  0.145
1986 Honer WG, Thompson C, Lightman SL, Williams TD, Checkley SA. No effect of naloxone on plasma oxytocin in normal men. Psychoneuroendocrinology. 11: 245-8. PMID 3749403 DOI: 10.1016/0306-4530(86)90061-2  0.144
2012 Dawson C, Dhanda A, Conway-Campbell B, Dimambro A, Lightman S, Dayan C. NFκB and glucocorticoid receptor activity in steroid resistance. Journal of Receptor and Signal Transduction Research. 32: 29-35. PMID 22185489 DOI: 10.3109/10799893.2011.641977  0.144
2002 Ueta Y, Levy A, Lightman SL. Gene expression in the supraoptic nucleus. Microscopy Research and Technique. 56: 158-63. PMID 11810718 DOI: 10.1002/JEMT.10020  0.144
1993 Hu SB, Tannahill LA, Lightman SL. Mechanisms of norepinephrine mediated corticotropin-releasing factor-41 release from cultured fetal hypothalamic cells. Neuroendocrinology. 56: 712-8. PMID 1488103 DOI: 10.1159/000126297  0.143
1986 Dixey JJ, Williams TD, Lightman SL, Lant AF, Brewerton DA. The effect of indomethacin on the renal response to arginine vasopressin in man. Clinical Science (London, England : 1979). 70: 409-16. PMID 3457670 DOI: 10.1042/CS0700409  0.143
2024 Daskas N, Sharples P, Likeman M, Lightman S, Crowne E. Cortisol dynamics, quality of life and fatigue following traumatic brain injury in childhood. Hormone Research in Paediatrics. PMID 38262374 DOI: 10.1159/000535231  0.143
1988 Lightman SL, Young WS. Vasopressin, oxytocin, dynorphin, enkephalin and corticotrophin-releasing factor mRNA stimulation in the rat. The Journal of Physiology. 394: 23-39. PMID 2895179 DOI: 10.1113/jphysiol.1987.sp016858  0.143
2020 Fudulu DP, Angelini GD, Papadopoulou FF, Evans J, Walker-Smith T, Kema I, Van Faassen M, Stoica S, Caputo M, Lightman S, Gibbison B. Correction to: The Peacock study: feasibility of the dynamic characterisation of the paediatric hypothalamic-pituitary-adrenal function during and after cardiac surgery. Bmc Cardiovascular Disorders. 20: 276. PMID 32513109 DOI: 10.1186/s12872-020-01561-7  0.142
2004 Bailey JE, Argyropoulos SV, Lightman SL, Nutt DJ. Does the brain noradrenaline network mediate the effects of the CO2 challenge? Journal of Psychopharmacology (Oxford, England). 17: 252-9. PMID 14513913 DOI: 10.1177/02698811030173002  0.142
1989 Williams TD, Walsh KP, Canepa-Anson R, Noble MI, Drake-Holland AJ, Sutton R, Lightman SL. Atrial natriuretic peptide response to rapid atrial pacing in cardiac-denervated dogs. The American Journal of Physiology. 257: R162-7. PMID 2526592 DOI: 10.1152/AJPREGU.1989.257.1.R162  0.142
1989 Poole CJ, Lightman SL. Inhibition of vasopressin secretion during migraine. Journal of Neurology, Neurosurgery, and Psychiatry. 51: 1441-4. PMID 2976811 DOI: 10.1136/jnnp.51.11.1441  0.141
2012 Galhardo J, Hunt LP, Lightman SL, Sabin MA, Bergh C, Sodersten P, Shield JP. Normalizing eating behavior reduces body weight and improves gastrointestinal hormonal secretion in obese adolescents. The Journal of Clinical Endocrinology and Metabolism. 97: E193-201. PMID 22162463 DOI: 10.1210/jc.2011-1999  0.141
2010 Vedhara K, Brant H, Alexiou A, Petrie KJ, Miles JN, Lightman SL. An investigation into the effects of social evaluation on cardiovascular and endocrine responses to the CO2 stress test in humans. Stress (Amsterdam, Netherlands). 13: 195-202. PMID 20392191 DOI: 10.3109/10253890903191440  0.141
2002 Lightman S. Somatuline Autogel: an extended release lanreotide formulation. Hospital Medicine (London, England : 1998). 63: 162-5. PMID 11933820 DOI: 10.12968/HOSP.2002.63.3.2062  0.141
1984 Brooks PT, Few J, Lightman SL. Development of Cortisol Rhythms in Man Clinical Science. 66: 17P-17P. DOI: 10.1042/CS066017PB_PT2  0.141
1991 Jessop DS, Chowdrey HS, Lightman SL. Substance P and substance K in the median eminence and paraventricular nucleus of the rat hypothalamus. Neuropeptides. 17: 135-40. PMID 1707503 DOI: 10.1016/0143-4179(90)90076-B  0.141
1987 Walsh KP, Williams TD, Canepa-Anson R, Pitts E, Lightman SL, Sutton R. Effects of endogenous atrial natriuretic peptide released by rapid atrial pacing in dogs. The American Journal of Physiology. 253: R599-604. PMID 2959163 DOI: 10.1152/AJPREGU.1987.253.4.R599  0.14
1999 Hernandez-Pando R, de la Luz Streber M, Orozco H, Arriaga K, Pavon L, Marti O, Lightman SL, Rook GA. Emergent immunoregulatory properties of combined glucocorticoid and anti-glucocorticoid steroids in a model of tuberculosis. Qjm : Monthly Journal of the Association of Physicians. 91: 755-66. PMID 10024939 DOI: 10.1093/QJMED/91.11.755  0.14
1988 Moratalla R, Vallejo M, Lightman SL. Vasopressin stimulates inositol phospholipid metabolism in rat medulla oblongata in vivo. Brain Research. 450: 398-402. PMID 2969763 DOI: 10.1016/0006-8993(88)91583-1  0.14
1990 Johnson MR, Bower M, Seckl JR, Lightman SL. Neurohypophysial secretion to insulin-induced hypoglycemia and its regulation by endogenous opioids in women. Acta Endocrinologica. 122: 467-71. PMID 2185602 DOI: 10.1530/ACTA.0.1220467  0.14
1982 Franks S, Lightman SL, MaClusky NJ, Naftolin F, Lynch SS, Butt WR, Jacobs HS. Failure of 2-hydroxyoestrone to lower prolactin concentrations in hyperprolactinaemic women. Clinical Endocrinology. 15: 385-9. PMID 7318190 DOI: 10.1111/j.1365-2265.1981.tb00678.x  0.14
Hide low-probability matches.