| Year |
Citation |
Score |
| 2023 |
Lin FT, Liu K, Garan LAW, Folly-Kossi H, Song Y, Lin SJ, Lin WC. A small-molecule inhibitor of TopBP1 exerts anti-MYC activity and synergy with PARP inhibitors. Proceedings of the National Academy of Sciences of the United States of America. 120: e2307793120. PMID 37878724 DOI: 10.1073/pnas.2307793120 |
0.335 |
|
| 2023 |
Folly-Kossi H, Graves JD, Garan LAW, Lin FT, Lin WC. DNA2 Nuclease Inhibition Confers Synthetic Lethality in Cancers with Mutant p53 and Synergizes with PARP Inhibitors. Cancer Research Communications. 3: 2096-2112. PMID 37756561 DOI: 10.1158/2767-9764.CRC-23-0166 |
0.392 |
|
| 2021 |
Liu K, Graves JD, Lin FT, Lin WC. Overexpression of TopBP1, a canonical ATR/Chk1 activator, paradoxically hinders ATR/Chk1 activation in cancer. The Journal of Biological Chemistry. 100382. PMID 33556369 DOI: 10.1016/j.jbc.2021.100382 |
0.35 |
|
| 2020 |
Graves JD, Lee YJ, Liu K, Li G, Lin FT, Lin WC. E2F1 sumoylation as a protective cellular mechanism in oxidative stress response. Proceedings of the National Academy of Sciences of the United States of America. PMID 32541040 DOI: 10.1073/Pnas.1921554117 |
0.383 |
|
| 2020 |
Liu K, Graves JD, Lee YJ, Lin FT, Lin WC. Cell-cycle-dependent switch of TopBP1 functions by Cdk2 and Akt. Molecular and Cellular Biology. PMID 31964753 DOI: 10.1128/Mcb.00599-19 |
0.526 |
|
| 2019 |
Lee YJ, Ho SR, Graves JD, Xiao Y, Huang S, Lin WC. CGRRF1, a growth suppressor, regulates EGFR ubiquitination in breast cancer. Breast Cancer Research : Bcr. 21: 134. PMID 31801577 DOI: 10.1186/S13058-019-1212-2 |
0.358 |
|
| 2018 |
Ho SR, Lin WC. RNF144A Sustains EGFR Signaling to Promote EGF-Dependent Cell Proliferation. The Journal of Biological Chemistry. PMID 30171075 DOI: 10.1074/Jbc.Ra118.002887 |
0.398 |
|
| 2017 |
Liu K, Lin FT, Graves JD, Lee YJ, Lin WC. Mutant p53 perturbs DNA replication checkpoint control through TopBP1 and Treslin. Proceedings of the National Academy of Sciences of the United States of America. PMID 28439015 DOI: 10.1073/Pnas.1619832114 |
0.497 |
|
| 2016 |
Lin FT, Lin VY, Lin VT, Lin WC. TRIP6 antagonizes the recruitment of A20 and CYLD to TRAF6 to promote the LPA2 receptor-mediated TRAF6 activation. Cell Discovery. 2. PMID 27134758 DOI: 10.1038/Celldisc.2015.48 |
0.421 |
|
| 2015 |
Mahanic CS, Budhavarapu V, Graves JD, Li G, Lin WC. Regulation of E2 Promoter Binding Factor 1 (E2F1) transcriptional activity through a deubiquitinating enzyme, UCH37. The Journal of Biological Chemistry. PMID 26396186 DOI: 10.1074/Jbc.M115.659425 |
0.556 |
|
| 2015 |
Ho SR, Lee YJ, Lin WC. Regulation of RNF144A E3 ubiquitin ligase activity by self-association through its transmembrane domain. The Journal of Biological Chemistry. PMID 26216882 DOI: 10.1074/Jbc.M115.645499 |
0.398 |
|
| 2015 |
Lin F, Lin VTG, Lin VY, Lai Y, Chen C, Liu K, Lin W. Abstract POSTER-BIOL-1333: TRIP6 regulates p27KIP1to promote ovarian tumorigenesis Clinical Cancer Research. 21. DOI: 10.1158/1557-3265.Ovcasymp14-Poster-Biol-1333 |
0.444 |
|
| 2014 |
Chowdhury P, Lin GE, Liu K, Song Y, Lin FT, Lin WC. Targeting TopBP1 at a convergent point of multiple oncogenic pathways for cancer therapy. Nature Communications. 5: 5476. PMID 25400145 DOI: 10.1038/Ncomms6476 |
0.434 |
|
| 2014 |
Ho SR, Mahanic CS, Lee YJ, Lin WC. RNF144A, an E3 ubiquitin ligase for DNA-PKcs, promotes apoptosis during DNA damage. Proceedings of the National Academy of Sciences of the United States of America. 111: E2646-55. PMID 24979766 DOI: 10.1073/Pnas.1323107111 |
0.486 |
|
| 2013 |
Liu K, Graves JD, Scott JD, Li R, Lin WC. Akt switches TopBP1 function from checkpoint activation to transcriptional regulation through phosphoserine binding-mediated oligomerization. Molecular and Cellular Biology. 33: 4685-700. PMID 24081328 DOI: 10.1128/Mcb.00373-13 |
0.514 |
|
| 2013 |
Lin VT, Lin VY, Lai YJ, Chen CS, Liu K, Lin WC, Lin FT. TRIP6 regulates p27 KIP1 to promote tumorigenesis. Molecular and Cellular Biology. 33: 1394-409. PMID 23339869 DOI: 10.1128/MCB.01149-12 |
0.37 |
|
| 2012 |
Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A, Adeli K, Agholme L, Agnello M, Agostinis P, Aguirre-Ghiso JA, Ahn HJ, Ait-Mohamed O, Ait-Si-Ali S, Akematsu T, Akira S, ... Lin WW, ... Lin WC, et al. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy. 8: 445-544. PMID 22966490 DOI: 10.4161/Auto.19496 |
0.313 |
|
| 2012 |
Budhavarapu VN, White ED, Mahanic CS, Chen L, Lin FT, Lin WC. Regulation of E2F1 by APC/C Cdh1 via K11 linkage-specific ubiquitin chain formation. Cell Cycle (Georgetown, Tex.). 11: 2030-8. PMID 22580462 DOI: 10.4161/Cc.20643 |
0.49 |
|
| 2011 |
Ling S, Lin WC. EDD inhibits ATM-mediated phosphorylation of p53. The Journal of Biological Chemistry. 286: 14972-82. PMID 21383020 DOI: 10.1074/jbc.M110.182527 |
0.411 |
|
| 2010 |
Wang B, Ling S, Lin WC. 14-3-3Tau regulates Beclin 1 and is required for autophagy. Plos One. 5: e10409. PMID 20454448 DOI: 10.1371/journal.pone.0010409 |
0.373 |
|
| 2010 |
Paik JC, Wang B, Liu K, Lue JK, Lin WC. Regulation of E2F1-induced apoptosis by the nucleolar protein RRP1B. The Journal of Biological Chemistry. 285: 6348-63. PMID 20040599 DOI: 10.1074/Jbc.M109.072074 |
0.629 |
|
| 2010 |
Bhonde MR, Hanski ML, Stehr J, Jebautzke B, Peiró-Jordán R, Fechner H, Yokoyama KK, Lin WC, Zeitz M, Hanski C. Mismatch repair system decreases cell survival by stabilizing the tetraploid G1 arrest in response to SN-38. International Journal of Cancer. Journal International Du Cancer. 126: 2813-25. PMID 19739070 DOI: 10.1002/Ijc.24893 |
0.416 |
|
| 2009 |
Liu K, Bellam N, Lin HY, Wang B, Stockard CR, Grizzle WE, Lin WC. Regulation of p53 by TopBP1: a potential mechanism for p53 inactivation in cancer. Molecular and Cellular Biology. 29: 2673-93. PMID 19289498 DOI: 10.1128/Mcb.01140-08 |
0.507 |
|
| 2008 |
Yang SZ, Lin FT, Lin WC. MCPH1/BRIT1 cooperates with E2F1 in the activation of checkpoint, DNA repair and apoptosis. Embo Reports. 9: 907-15. PMID 18660752 DOI: 10.1038/Embor.2008.128 |
0.591 |
|
| 2007 |
Lin FT, Lai YJ, Makarova N, Tigyi G, Lin WC. The lysophosphatidic acid 2 receptor mediates down-regulation of Siva-1 to promote cell survival. The Journal of Biological Chemistry. 282: 37759-69. PMID 17965021 DOI: 10.1074/Jbc.M705025200 |
0.371 |
|
| 2007 |
Lai YJ, Lin WC, Lin FT. PTPL1/FAP-1 negatively regulates TRIP6 function in lysophosphatidic acid-induced cell migration. The Journal of Biological Chemistry. 282: 24381-7. PMID 17591779 DOI: 10.1074/jbc.M701499200 |
0.405 |
|
| 2006 |
Liu K, Paik JC, Wang B, Lin FT, Lin WC. Regulation of TopBP1 oligomerization by Akt/PKB for cell survival. The Embo Journal. 25: 4795-807. PMID 17006541 DOI: 10.1038/Sj.Emboj.7601355 |
0.62 |
|
| 2005 |
Lai YJ, Chen CS, Lin WC, Lin FT. c-Src-mediated phosphorylation of TRIP6 regulates its function in lysophosphatidic acid-induced cell migration. Molecular and Cellular Biology. 25: 5859-68. PMID 15988003 DOI: 10.1128/MCB.25.14.5859-5868.2005 |
0.348 |
|
| 2004 |
Wang B, Liu K, Lin FT, Lin WC. A role for 14-3-3 tau in E2F1 stabilization and DNA damage-induced apoptosis. The Journal of Biological Chemistry. 279: 54140-52. PMID 15494392 DOI: 10.1074/Jbc.M410493200 |
0.557 |
|
| 2004 |
Luo Y, Lin FT, Lin WC. ATM-mediated stabilization of hMutL DNA mismatch repair proteins augments p53 activation during DNA damage. Molecular and Cellular Biology. 24: 6430-44. PMID 15226443 DOI: 10.1128/Mcb.24.14.6430-6444.2004 |
0.5 |
|
| 2004 |
Liu K, Luo Y, Lin FT, Lin WC. TopBP1 recruits Brg1/Brm to repress E2F1-induced apoptosis, a novel pRb-independent and E2F1-specific control for cell survival. Genes & Development. 18: 673-86. PMID 15075294 DOI: 10.1101/Gad.1180204 |
0.615 |
|
| 2003 |
Liu K, Lin FT, Ruppert JM, Lin WC. Regulation of E2F1 by BRCT domain-containing protein TopBP1. Molecular and Cellular Biology. 23: 3287-304. PMID 12697828 DOI: 10.1128/Mcb.23.9.3287-3304.2003 |
0.565 |
|
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