| Year |
Citation |
Score |
| 2023 |
Gray GK, Girnius N, Kuiken HJ, Henstridge AZ, Brugge JS. Single-cell and spatial analyses reveal a tradeoff between murine mammary proliferation and lineage programs associated with endocrine cues. Cell Reports. 42: 113293. PMID 37858468 DOI: 10.1016/j.celrep.2023.113293 |
0.304 |
|
| 2020 |
Takahashi N, Cho P, Selfors LM, Kuiken HJ, Kaul R, Fujiwara T, Harris IS, Zhang T, Gygi SP, Brugge JS. 3D Culture Models with CRISPR Screens Reveal Hyperactive NRF2 as a Prerequisite for Spheroid Formation via Regulation of Proliferation and Ferroptosis. Molecular Cell. PMID 33128871 DOI: 10.1016/j.molcel.2020.10.010 |
0.307 |
|
| 2020 |
Zervantonakis IK, Poskus MD, Scott AL, Selfors LM, Lin JR, Dillon DA, Pathania S, Sorger PK, Mills GB, Brugge JS. Fibroblast-tumor cell signaling limits HER2 kinase therapy response via activation of MTOR and antiapoptotic pathways. Proceedings of the National Academy of Sciences of the United States of America. PMID 32601199 DOI: 10.1073/Pnas.2000648117 |
0.476 |
|
| 2020 |
Shu S, Wu HJ, Ge JY, Zeid R, Harris IS, Jovanović B, Murphy K, Wang B, Qiu X, Endress JE, Reyes J, Lim K, Font-Tello A, Syamala S, Xiao T, ... ... Brugge JS, et al. Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer. Molecular Cell. PMID 32416067 DOI: 10.1016/J.Molcel.2020.04.027 |
0.349 |
|
| 2020 |
Rosenbluth JM, Schackmann RCJ, Gray GK, Selfors LM, Li CM, Boedicker M, Kuiken HJ, Richardson A, Brock J, Garber J, Dillon D, Sachs N, Clevers H, Brugge JS. Organoid cultures from normal and cancer-prone human breast tissues preserve complex epithelial lineages. Nature Communications. 11: 1711. PMID 32249764 DOI: 10.1038/S41467-020-15548-7 |
0.387 |
|
| 2020 |
Caswell-Jin JL, McNamara KL, Dering J, Chen H, Dichmann R, Perez A, Patel R, Kotler E, Zoeller JJ, Brugge JS, Press MF, Slamon DJ, Curtis C, Hurvitz SA. Abstract P4-07-01: Tumor expression and microenvironment in HER2-positive breast cancer before and on HER2-targeted therapy: Analysis of microarray expression data from the TRIO-US B07 trial Cancer Research. 80. DOI: 10.1158/1538-7445.Sabcs19-P4-07-01 |
0.347 |
|
| 2020 |
Zoeller JJ, Vagodny A, Daniels VW, Taneja K, Tan BY, DeRose YS, Fujita M, Welm AL, Letai A, Leverson JD, Blot V, Bronson RT, Dillon DA, Brugge JS. Abstract P3-11-06: Pre-clinical assessment of combined ABT-263/Navitoclax and ABT-414 or ABBV-321 treatment for EGFR-expressing TNBC Cancer Research. 80. DOI: 10.1158/1538-7445.Sabcs19-P3-11-06 |
0.343 |
|
| 2020 |
Shapiro HK, Li CM, Tsiobikas C, Selfors L, Chen H, Gray K, Oren Y, Pinello L, Regev A, Brugge JS. Characterization of Mammary Cells Co‐expressing Separate Lineage Markers The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.01908 |
0.385 |
|
| 2019 |
Harris IS, Brugge JS. United They Stand, Divided They Fall. Cell Metabolism. 30: 624-625. PMID 31577930 DOI: 10.1016/J.Cmet.2019.09.008 |
0.31 |
|
| 2019 |
Press MF, Xie B, Davenport S, Zhou Y, Guzman R, Nolan GP, O'Brien N, Palazzolo M, Mak TW, Brugge JS, Slamon DJ. Role for polo-like kinase 4 in mediation of cytokinesis. Proceedings of the National Academy of Sciences of the United States of America. PMID 31097597 DOI: 10.1073/Pnas.1818820116 |
0.45 |
|
| 2019 |
Zoeller JJ, Vagodny A, Taneja K, Tan BY, O'Brien N, Slamon DJ, Sampath D, Leverson JD, Bronson RT, Dillon DA, Brugge JS. Neutralization of BCL-2/XL enhances the cytotoxicity of T-DM1 in vivo. Molecular Cancer Therapeutics. PMID 30962322 DOI: 10.1158/1535-7163.Mct-18-0743 |
0.334 |
|
| 2019 |
Bast RC, Matulonis UA, Sood AK, Ahmed AA, Amobi AE, Balkwill FR, Wielgos-Bonvallet M, Bowtell DDL, Brenton JD, Brugge JS, Coleman RL, Draetta GF, Doberstein K, Drapkin RI, Eckert MA, et al. Critical questions in ovarian cancer research and treatment: Report of an American Association for Cancer Research Special Conference. Cancer. PMID 30835824 DOI: 10.1002/Cncr.32004 |
0.311 |
|
| 2019 |
Harris IS, Endress JE, Coloff JL, Selfors LM, McBrayer SK, Rosenbluth JM, Takahashi N, Dhakal S, Koduri V, Oser MG, Schauer NJ, Doherty LM, Hong AL, Kang YP, Younger ST, ... ... Brugge JS, et al. Deubiquitinases Maintain Protein Homeostasis and Survival of Cancer Cells upon Glutathione Depletion. Cell Metabolism. PMID 30799286 DOI: 10.1016/J.Cmet.2019.01.020 |
0.459 |
|
| 2019 |
Iavarone C, Zervantonakis IK, Selfors LM, Palakurthi S, Liu JF, Drapkin R, Matulonis UA, Hallberg D, Velculescu VE, Leverson JD, Sampath D, Mills GB, Brugge JS. Combined MEK and BCL-2/XL inhibition is effective in high-grade serous ovarian cancer patient-derived xenograft models and BIM levels are predictive of responsiveness. Molecular Cancer Therapeutics. PMID 30679390 DOI: 10.1158/1535-7163.Mct-18-0413 |
0.386 |
|
| 2019 |
Rosenbluth J, Zervantonakis I, Boedicker M, Wagle N, Dillon D, Nakhlis F, Brugge J, Overmoyer B. Abstract P5-17-01: Patient-derived organoid models of inflammatory breast cancer Cancer Research. 79. DOI: 10.1158/1538-7445.Sabcs18-P5-17-01 |
0.367 |
|
| 2019 |
Brugge J. Abstract ES6-1: Oxidative stress responses in cancer Cancer Research. 79. DOI: 10.1158/1538-7445.Sabcs18-Es6-1 |
0.372 |
|
| 2019 |
Kuiken HJ, Friend CM, Corsello SM, Mader CC, Brugge JS. Abstract 3775: Characterization of intratumoral heterogeneity in drug sensitivity and modeling of drug combination effects using subclonal cell populations derived from a single breast cancer cell line Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-3775 |
0.35 |
|
| 2019 |
Zoeller JJ, Hurvitz SA, Press MF, Selfors LM, Dering J, Slamon DJ, Brugge JS. Abstract 2978: Clinical evaluation of lapatinib induced BCL-2 adaptive responses Cancer Research. 79: 2978-2978. DOI: 10.1158/1538-7445.Sabcs18-2978 |
0.345 |
|
| 2019 |
Cho P, Takahashi N, Selfors LM, Kuiken HJ, Brugge JS. Abstract 884: Interplay between NRF2 and GPX4 is critical for cancer cell survival in 3D spheroids Cancer Research. 79: 884-884. DOI: 10.1158/1538-7445.Am2019-884 |
0.45 |
|
| 2019 |
Oren Y, Thakore P, Cuoco MS, Cabanos HF, Hata A, Brugge JS, Regev A. Abstract 2101: Targeting the root of cancer persister cells using an expressed barcode library Cancer Research. 79: 2101-2101. DOI: 10.1158/1538-7445.Am2019-2101 |
0.447 |
|
| 2019 |
Friend CM, Brugge JS, Kuiken HJ, Corsello SM, Mader CC. Abstract A132: Characterization of intratumoral heterogeneity in drug sensitivity and non-cell autonomous mechanisms of drug resistance using subclonal cell populations derived from a single breast cancer cell line Molecular Cancer Therapeutics. DOI: 10.1158/1535-7163.Targ-19-A132 |
0.373 |
|
| 2018 |
Walker SJ, Selfors LM, Margolis BL, Brugge JS. CRB3 and the FERM protein EPB41L4B regulate proliferation of mammary epithelial cells through the release of amphiregulin. Plos One. 13: e0207470. PMID 30440051 DOI: 10.1371/Journal.Pone.0207470 |
0.445 |
|
| 2018 |
Takahashi N, Chen HY, Harris IS, Stover DG, Selfors LM, Bronson RT, Deraedt T, Cichowski K, Welm AL, Mori Y, Mills GB, Brugge JS. Cancer Cells Co-opt the Neuronal Redox-Sensing Channel TRPA1 to Promote Oxidative-Stress Tolerance. Cancer Cell. PMID 29805077 DOI: 10.1016/J.Ccell.2018.05.001 |
0.334 |
|
| 2018 |
Li CM, Oren Y, Regev A, Brugge JS. Abstract PR06: Contribution of mutant microenvironment to hereditary cancer: Single-cell gene expression profiling of a genetically engineered mouse model of human hereditary BRCA1-related breast cancer Cancer Research. 78. DOI: 10.1158/1538-7445.Mousemodels17-Pr06 |
0.397 |
|
| 2018 |
Rosenbluth JM, Schackmann R, Li C, Sachs N, Dillon D, Richardson A, Brock J, Garber J, Gray GK, Zoeller J, Boedicker M, Kuiken HJ, Clevers H, Brugge J. Abstract 989: Organoid cultures from normal and cancer-prone human breast tissues preserve complex epithelial lineages and can form chimeric mammary glands in vivo Cancer Research. 78: 989-989. DOI: 10.1158/1538-7445.Am2018-989 |
0.393 |
|
| 2018 |
Oren Y, Regev A, Brugge J. Abstract 3301: Using a novel single-cell lineage-tracing technique to uncover the mechanisms driving nongenetic cancer relapse Cancer Research. 78: 3301-3301. DOI: 10.1158/1538-7445.Am2018-3301 |
0.432 |
|
| 2018 |
Hendrick NM, Iwanicki MP, Li CM, Bui DA, Selfors LM, Brugge JS. Abstract 3155: Loss of YAP1 dysregulates RhoA signaling and promotes cell invasion Cancer Research. 78: 3155-3155. DOI: 10.1158/1538-7445.Am2018-3155 |
0.496 |
|
| 2018 |
Hamalian S, Güth R, Zervantonakis I, Duell E, Lin J, Shisgal P, Molnar J, Geller C, Agajanian M, Tchou J, Sorger PK, Brugge JS, Kelber JA. Abstract 2140: Mesenchymal stromal cells expressing a PEAK1/Cripto axis sustain pro-survival NF-κB signaling in adjacent tumor cells to promote disease progression and therapy resistance Cancer Research. 78: 2140-2140. DOI: 10.1158/1538-7445.Am2018-2140 |
0.672 |
|
| 2018 |
Endress JE, Harris IS, Stewart-Ornstein J, Lahav G, Brugge JS. Abstract 1851: Combined inhibition of PARP and the unfolded protein response synergistically reduces viability in BRCA1-mutant breast cancer cells Cancer Research. 78: 1851-1851. DOI: 10.1158/1538-7445.Am2018-1851 |
0.422 |
|
| 2017 |
Hung YP, Teragawa C, Kosaisawe N, Gillies TE, Pargett M, Minguet M, Distor K, Rocha-Gregg BL, Coloff JL, Keibler MA, Stephanopoulos G, Yellen G, Brugge JS, Albeck JG. Akt regulation of glycolysis mediates bioenergetic stability in epithelial cells. Elife. 6. PMID 29239720 DOI: 10.7554/Elife.27293 |
0.422 |
|
| 2017 |
Selfors LM, Stover DG, Harris IS, Brugge JS, Coloff JL. Identification of cancer genes that are independent of dominant proliferation and lineage programs. Proceedings of the National Academy of Sciences of the United States of America. 114: E11276-E11284. PMID 29229826 DOI: 10.1073/Pnas.1714877115 |
0.407 |
|
| 2017 |
Zervantonakis IK, Iavarone C, Chen HY, Selfors LM, Palakurthi S, Liu JF, Drapkin R, Matulonis U, Leverson JD, Sampath D, Mills GB, Brugge JS. Systems analysis of apoptotic priming in ovarian cancer identifies vulnerabilities and predictors of drug response. Nature Communications. 8: 365. PMID 28848242 DOI: 10.1038/S41467-017-00263-7 |
0.401 |
|
| 2017 |
Zoeller JJ, Bronson RT, Selfors LM, Mills GB, Brugge JS. Niche-localized tumor cells are protected from HER2-targeted therapy via upregulation of an anti-apoptotic program in vivo. Npj Breast Cancer. 3: 18. PMID 28649658 DOI: 10.1038/s41523-017-0020-z |
0.312 |
|
| 2017 |
Sun C, Fang Y, Yin J, Chen J, Ju Z, Zhang D, Chen X, Vellano CP, Jeong KJ, Ng PK, Eterovic AKB, Bhola NH, Lu Y, Westin SN, Grandis JR, ... ... Brugge J, et al. Rational combination therapy with PARP and MEK inhibitors capitalizes on therapeutic liabilities in RAS mutant cancers. Science Translational Medicine. 9. PMID 28566428 DOI: 10.1126/Scitranslmed.Aal5148 |
0.322 |
|
| 2017 |
Coloff JL, Brugge JS. Metabolic changes promote rejection of oncogenic cells. Nature Cell Biology. 19: 414-415. PMID 28446818 DOI: 10.1038/Ncb3521 |
0.447 |
|
| 2017 |
Muranen T, Iwanicki MP, Curry NL, Hwang J, DuBois CD, Coloff JL, Hitchcock DS, Clish CB, Brugge JS, Kalaany NY. Starved epithelial cells uptake extracellular matrix for survival. Nature Communications. 8: 13989. PMID 28071763 DOI: 10.1038/Ncomms13989 |
0.464 |
|
| 2017 |
Hung YP, Teragawa C, Kosaisawe N, Gillies TE, Pargett M, Minguet M, Distor K, Rocha-Gregg BL, Coloff JL, Keibler MA, Stephanopoulos G, Yellen G, Brugge JS, Albeck JG. Author response: Akt regulation of glycolysis mediates bioenergetic stability in epithelial cells Elife. DOI: 10.7554/Elife.27293.038 |
0.403 |
|
| 2017 |
Zervantonakis IK, Iavarone C, Chen H, Leverson J, Sampath D, Palakurthi S, Drapkin R, Liu JF, Matulonis U, Mills G, Brugge JS. Abstract PR01: Systems analysis of signaling pathway adaptation to design effective PI3K-based combination therapies using ovarian cancer patient-derived xenografts Cancer Research. 77. DOI: 10.1158/1538-7445.Epso16-Pr01 |
0.403 |
|
| 2017 |
Takahashi N, Chen H, Harris I, Stover D, Bronson R, Deraedt T, Cichowski K, Welm A, Mills G, Brugge J. Abstract 5478: The TRPA1 Ca2+-permeable channel mediates a non-canonical redox adaptation in cancer cells Cancer Research. 77: 5478-5478. DOI: 10.1158/1538-7445.Am2017-5478 |
0.447 |
|
| 2017 |
Harris IS, Endress JE, Brugge JS. Abstract 4985: Understanding the vulnerabilities in cancer cells upon inhibition of glutathione synthesis Cancer Research. 77: 4985-4985. DOI: 10.1158/1538-7445.Am2017-4985 |
0.445 |
|
| 2017 |
Iavarone C, Zervantonakis I, Selfors LM, Palakurthi S, Liu JF, Matulonis UA, Drapkin RI, Mills GB, Leverson JD, Sampath D, Brugge JS. Abstract 4033: Combined MEK and BCL-2/XLinhibition as a potential drug combination for the treatment of high-grade serous ovarian cancer Cancer Research. 77: 4033-4033. DOI: 10.1158/1538-7445.Am2017-4033 |
0.418 |
|
| 2017 |
Kuiken HJ, Dhakal S, Selfors LM, Crowdis JP, Bhang HC, Stegmeier F, Mills GB, Brugge JS. Abstract 3957: Characterization of functional heterogeneity andin vivodynamics of clonal cell populations derived from the triple-negative breast cancer cell line MDA-MB-468 Cancer Research. 77: 3957-3957. DOI: 10.1158/1538-7445.Am2017-3957 |
0.395 |
|
| 2016 |
Muranen T, Selfors LM, Hwang J, Gallegos LL, Coloff JL, Thoreen CC, Kang SA, Sabatini DM, Mills GB, Brugge JS. ERK and p38 MAPK Activities Determine Sensitivity to PI3K/mTOR Inhibition via Regulation of MYC and YAP. Cancer Research. PMID 27913436 DOI: 10.1158/0008-5472.Can-16-0155 |
0.436 |
|
| 2016 |
Liu JF, Palakurthi S, Zeng Q, Zhou S, Ivanova E, Huang W, Zervantonakis IK, Selfors LM, Shen Y, Pritchard CC, Zheng M, Adleff V, Papp E, Piao H, Novak M, ... ... Brugge JS, et al. Establishment of patient-derived tumor xenograft models of epithelial ovarian cancer for pre-clinical evaluation of novel therapeutics. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 27573169 DOI: 10.1158/1078-0432.Ccr-16-1237 |
0.323 |
|
| 2016 |
Iwanicki MP, Chen HY, Iavarone C, Zervantonakis IK, Muranen T, Novak M, Ince TA, Drapkin R, Brugge JS. Mutant p53 regulates ovarian cancer transformed phenotypes through autocrine matrix deposition. Jci Insight. 1. PMID 27482544 DOI: 10.1172/Jci.Insight.86829 |
0.428 |
|
| 2016 |
Stover DG, Coloff JL, Barry WT, Brugge JS, Winer EP, Selfors LM. The Role of Proliferation in Determining Response to Neoadjuvant Chemotherapy in Breast Cancer: A Gene Expression-Based Meta-Analysis. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 27330058 DOI: 10.1158/1078-0432.Ccr-16-0471 |
0.338 |
|
| 2016 |
Gallegos LL, Ng MR, Sowa ME, Selfors LM, White A, Zervantonakis IK, Singh P, Dhakal S, Harper JW, Brugge JS. A protein interaction map for cell-cell adhesion regulators identifies DUSP23 as a novel phosphatase for β-catenin. Scientific Reports. 6: 27114. PMID 27255161 DOI: 10.1038/Srep27114 |
0.784 |
|
| 2016 |
Coloff JL, Brugge JS. How tumor cells cope with the metabolic stress of leaving home. Cell Research. PMID 27216116 DOI: 10.1038/Cr.2016.61 |
0.399 |
|
| 2016 |
Coloff JL, Murphy JP, Braun CR, Harris IS, Shelton LM, Kami K, Gygi SP, Selfors LM, Brugge JS. Differential Glutamate Metabolism in Proliferating and Quiescent Mammary Epithelial Cells. Cell Metabolism. PMID 27133130 DOI: 10.1016/J.Cmet.2016.03.016 |
0.434 |
|
| 2016 |
Bui DA, Lee W, White AE, Harper JW, Schackmann RC, Overholtzer M, Selfors LM, Brugge JS. Cytokinesis involves a nontranscriptional function of the Hippo pathway effector YAP. Science Signaling. 9: ra23. PMID 26933062 DOI: 10.1126/Scisignal.Aaa9227 |
0.433 |
|
| 2016 |
Iwanicki MP, Chen H, Zervantonakis I, Novak M, Muranen T, Ince TA, Drapkin R, Brugge JS. Abstract PR12: Mutant p53 drives early events in fallopian tube tumorigenesis through mesenchyme-associated autocrine production of matrix that supports survival and mesothelial intercalation. Clinical Cancer Research. 22. DOI: 10.1158/1557-3265.Ovca15-Pr12 |
0.446 |
|
| 2016 |
Iavarone C, Zervantonakis I, Chen H, Palakurthi SS, Liu JF, Matulonis UA, Drapkin RI, Mills GB, Leverson JD, Sampath D, Brugge JS. Abstract B48: Design of effective combination therapies for high-grade serous ovarian cancer using patient-derived xenograft models. Clinical Cancer Research. 22. DOI: 10.1158/1557-3265.Ovca15-B48 |
0.387 |
|
| 2016 |
Stover D, Waks A, Erica M, Brugge J, Winer E, Selfors L. Abstract P3-07-31: Immune activation signatures identify a subset of ER+ breast cancers with increased pathologic complete response to neoadjuvant chemotherapy Cancer Research. 76. DOI: 10.1158/1538-7445.Sabcs15-P3-07-31 |
0.314 |
|
| 2016 |
Iavarone C, Zervantonakis I, Chen H, Palakurthi SS, Liu JF, Matulonis U, Drapkin R, Mills G, Leverson J, Sampath D, Brugge J. Abstract 3843: Design of effective combination therapies for high-grade serous ovarian cancer using patient-derived xenograft models Cancer Research. 76: 3843-3843. DOI: 10.1158/1538-7445.Am2016-3843 |
0.389 |
|
| 2016 |
Press MF, Xie B, Davenport S, Zhou Y, O’Brien N, Palazzolo M, Mak T, Brugge J, Slamon DJ. Abstract 2736: Regulation of cytokinesis by polo-like kinase 4 Cancer Research. 76: 2736-2736. DOI: 10.1158/1538-7445.Am2016-2736 |
0.449 |
|
| 2015 |
Harris IS, Brugge JS. Cancer: The enemy of my enemy is my friend. Nature. 527: 170-1. PMID 26503052 DOI: 10.1038/Nature15644 |
0.393 |
|
| 2015 |
Ince TA, Sousa AD, Jones MA, Harrell JC, Agoston ES, Krohn M, Selfors LM, Liu W, Chen K, Yong M, Buchwald P, Wang B, Hale KS, Cohick E, Sergent P, ... ... Brugge JS, et al. Characterization of twenty-five ovarian tumour cell lines that phenocopy primary tumours. Nature Communications. 6: 7419. PMID 26080861 DOI: 10.1038/Ncomms8419 |
0.359 |
|
| 2015 |
Sever R, Brugge JS. Signal transduction in cancer. Cold Spring Harbor Perspectives in Medicine. 5. PMID 25833940 DOI: 10.1101/Cshperspect.A006098 |
0.439 |
|
| 2015 |
Ng MR, Besser A, Brugge JS, Danuser G. Correction: Mapping the dynamics of force transduction at cell-cell junctions of epithelial clusters. Elife. 4: e06656. PMID 25642646 DOI: 10.7554/Elife.06656 |
0.749 |
|
| 2015 |
Stover DG, Selfors LM, Coloff JL, Brugge JS, Winer EP. Meta-analysis of breast cancer expression data using published gene signatures to reveal key cellular processes implicated in chemosensitivity and resistance. Journal of Clinical Oncology. 33: 509-509. DOI: 10.1200/Jco.2015.33.15_Suppl.509 |
0.357 |
|
| 2015 |
Zervantonakis I, Chen H, Muranen T, Liu J, Drapkin R, Matulonis U, Brugge J. Abstract PR01: Adaptive resistance of patient-derived ovarian cancer cells to PI3K/mTOR inhibition Clinical Cancer Research. 21. DOI: 10.1158/1557-3265.Pms14-Pr01 |
0.429 |
|
| 2015 |
Muranen T, Selfors LM, Thoreen CC, Gallegos LL, Coloff JL, Mills GB, Brugge JS. Abstract PR03: The Hippo pathway effector YAP1 contributes to escape from proliferation arrest under chronic PI3K/mTOR inhibition Molecular Cancer Therapeutics. 14. DOI: 10.1158/1538-8514.Pi3K14-Pr03 |
0.429 |
|
| 2014 |
Ng MR, Besser A, Brugge JS, Danuser G. Mapping the dynamics of force transduction at cell-cell junctions of epithelial clusters. Elife. 3: e03282. PMID 25479385 DOI: 10.7554/Elife.03282 |
0.763 |
|
| 2014 |
Gallegos LL, Brugge JS. Live free or die: cell-cell adhesion regulates sensitivity to trail-induced apoptosis. Developmental Cell. 30: 3-4. PMID 25026030 DOI: 10.1016/J.Devcel.2014.06.031 |
0.429 |
|
| 2014 |
Davidowitz RA, Selfors LM, Iwanicki MP, Elias KM, Karst A, Piao H, Ince TA, Drage MG, Dering J, Konecny GE, Matulonis U, Mills GB, Slamon DJ, Drapkin R, Brugge JS. Mesenchymal gene program-expressing ovarian cancer spheroids exhibit enhanced mesothelial clearance. The Journal of Clinical Investigation. 124: 2611-25. PMID 24762435 DOI: 10.1172/Jci69815 |
0.821 |
|
| 2014 |
Godinho SA, Picone R, Burute M, Dagher R, Su Y, Leung CT, Polyak K, Brugge JS, Théry M, Pellman D. Oncogene-like induction of cellular invasion from centrosome amplification. Nature. 510: 167-71. PMID 24739973 DOI: 10.1038/Nature13277 |
0.439 |
|
| 2014 |
Amara SN, Selfors L, Krohn M, Ince T, Mills G, Brugge J. Abstract 2976: Intratumoral cellular heterogeneity of epithelial ovarian carcinoma and its impact on tumor behavior Cancer Research. 74: 2976-2976. DOI: 10.1158/1538-7445.Am2014-2976 |
0.412 |
|
| 2013 |
Kaanta AS, Virtanen C, Selfors LM, Brugge JS, Neel BG. Evidence for a multipotent mammary progenitor with pregnancy-specific activity. Breast Cancer Research : Bcr. 15: R65. PMID 23947835 DOI: 10.1186/Bcr3459 |
0.723 |
|
| 2013 |
Vakifahmetoglu-Norberg H, Kim M, Xia HG, Iwanicki MP, Ofengeim D, Coloff JL, Pan L, Ince TA, Kroemer G, Brugge JS, Yuan J. Chaperone-mediated autophagy degrades mutant p53. Genes & Development. 27: 1718-30. PMID 23913924 DOI: 10.1101/Gad.220897.113 |
0.395 |
|
| 2013 |
Buchwalter G, Hickey MM, Cromer A, Selfors LM, Gunawardane RN, Frishman J, Jeselsohn R, Lim E, Chi D, Fu X, Schiff R, Brown M, Brugge JS. PDEF promotes luminal differentiation and acts as a survival factor for ER-positive breast cancer cells. Cancer Cell. 23: 753-67. PMID 23764000 DOI: 10.1016/J.Ccr.2013.04.026 |
0.35 |
|
| 2013 |
Albeck JG, Mills GB, Brugge JS. Frequency-modulated pulses of ERK activity transmit quantitative proliferation signals. Molecular Cell. 49: 249-61. PMID 23219535 DOI: 10.1016/J.Molcel.2012.11.002 |
0.372 |
|
| 2013 |
Muranen TE, Coloff J, Selfors L, Bui A, Mills GB, Brugge JS. Abstract 4451: Long-term resistance to PI3K/mTOR inhibition requires increased expression of c-myc and YAP. Cancer Research. 73: 4451-4451. DOI: 10.1158/1538-7445.Am2013-4451 |
0.381 |
|
| 2013 |
Amara SN, Selfors LM, Krohn M, Ince TA, Rueda BR, Foster R, Mills GB, Brugge JS. Abstract PR09: Cellular heterogeneity of ovarian carcinoma cells and its impact on tumor behavior Clinical Cancer Research. 19. DOI: 10.1158/1078-0432.Ovca13-Pr09 |
0.412 |
|
| 2013 |
Iwanicki MP, Novak M, Zervantonakis IK, Ince TA, Drapkin R, Brugge JS. Abstract A7: Targeting mutant p53 and cell-cell adhesion in ovarian cancer Clinical Cancer Research. 19. DOI: 10.1158/1078-0432.Ovca13-A7 |
0.393 |
|
| 2012 |
Mouneimne G, Hansen SD, Selfors LM, Petrak L, Hickey MM, Gallegos LL, Simpson KJ, Lim J, Gertler FB, Hartwig JH, Mullins RD, Brugge JS. Differential remodeling of actin cytoskeleton architecture by profilin isoforms leads to distinct effects on cell migration and invasion. Cancer Cell. 22: 615-30. PMID 23153535 DOI: 10.1016/J.Ccr.2012.09.027 |
0.422 |
|
| 2012 |
Ng MR, Besser A, Danuser G, Brugge JS. Substrate stiffness regulates cadherin-dependent collective migration through myosin-II contractility. The Journal of Cell Biology. 199: 545-63. PMID 23091067 DOI: 10.1083/Jcb.201207148 |
0.777 |
|
| 2012 |
Worster DT, Schmelzle T, Solimini NL, Lightcap ES, Millard B, Mills GB, Brugge JS, Albeck JG. Akt and ERK control the proliferative response of mammary epithelial cells to the growth factors IGF-1 and EGF through the cell cycle inhibitor p57Kip2. Science Signaling. 5: ra19. PMID 22394561 DOI: 10.1126/Scisignal.2001986 |
0.386 |
|
| 2012 |
Davidowitz RA, Iwanicki MP, Brugge JS. In vitro mesothelial clearance assay that models the early steps of ovarian cancer metastasis. Journal of Visualized Experiments : Jove. PMID 22371143 DOI: 10.3791/3888 |
0.82 |
|
| 2012 |
Muranen T, Selfors LM, Worster DT, Iwanicki MP, Song L, Morales FC, Gao S, Mills GB, Brugge JS. Inhibition of PI3K/mTOR leads to adaptive resistance in matrix-attached cancer cells. Cancer Cell. 21: 227-39. PMID 22340595 DOI: 10.1016/J.Ccr.2011.12.024 |
0.412 |
|
| 2012 |
Leung CT, Brugge JS. Outgrowth of single oncogene-expressing cells from suppressive epithelial environments. Nature. 482: 410-3. PMID 22318515 DOI: 10.1038/Nature10826 |
0.517 |
|
| 2012 |
Lee J, Ng MR, Sinkevicius KW, Kim CF, Danuser G, Brugge JS, Haigis MC. Altered metabolic requirements in cancer cell migration and metastasis Bmc Proceedings. 6. DOI: 10.1186/1753-6561-6-S3-P32 |
0.779 |
|
| 2012 |
Locasale JW, Grassian A, Beroukhim R, Meyerson M, Wagner G, Asara JM, Brugge JS, Vander Heiden MG, Cantley LC. Amplification of phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis Bmc Proceedings. 6. DOI: 10.1186/1753-6561-6-S3-O15 |
0.786 |
|
| 2012 |
Leya G, Albeck J, Brugge J. Abstract LB-418: A live-cell miRNA reporter library for identifying non-genetic drug resistance networks at single-cell resolution Cancer Research. 72. DOI: 10.1158/1538-7445.Am2012-Lb-418 |
0.385 |
|
| 2012 |
Albeck JG, Mills GB, Brugge JS. Abstract 4946: Control of cellular proliferation by ERK: A quantitative analysis in single cells Cancer Research. 72: 4946-4946. DOI: 10.1158/1538-7445.Am2012-4946 |
0.355 |
|
| 2012 |
Muranen TE, Selfors L, Worster D, Iwanicki M, Song L, Morlaes F, Mills GB, Brugge JS. Abstract 4836: Inhibition of PI3K/mTOR leads to adaptive resistance in extracellular matrix attached cancer cells Cancer Research. 72: 4836-4836. DOI: 10.1158/1538-7445.Am2012-4836 |
0.413 |
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| 2012 |
Zoeller JJ, Bronson RT, Gilmer TM, Selfors LM, Lu Y, Mills GB, Brugge JS. Abstract P4-08-05: Basement membrane localized tumor cells are protected from HER2-targeted therapy in vivo. Cancer Research. 72: 4834-4834. DOI: 10.1158/0008-5472.Sabcs12-P4-08-05 |
0.452 |
|
| 2012 |
Albeck JG, Brugge JS, VanHook AM. Science Signaling Podcast: 6 March 2012 Science Signaling. 5: pc5-pc5. DOI: 10.1126/Scisignal.2002959 |
0.375 |
|
| 2012 |
Schnaar R, Paulson JC, Macauley MS, Nycholat C, Pfrengle F, Rademacher C, Mahan A, Dionne K, Suscovich T, Alter G, Katoh T, Kiwamoto T, Brummet M, Bochner B, Tiemeyer M, ... ... Brugge J, et al. Program and abstracts for the 2012 Joint Meeting of the Society for Glycobiology & American Society for Matrix Biology Glycobiology. 22: 1518-1650. DOI: 10.1093/Glycob/Cws127 |
0.343 |
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| 2011 |
Iwanicki MP, Davidowitz RA, Ng MR, Besser A, Muranen T, Merritt M, Danuser G, Ince TA, Ince T, Brugge JS. Ovarian cancer spheroids use myosin-generated force to clear the mesothelium. Cancer Discovery. 1: 144-57. PMID 22303516 DOI: 10.1158/2159-8274.Cd-11-0010 |
0.797 |
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| 2011 |
Grassian AR, Coloff JL, Brugge JS. Extracellular matrix regulation of metabolism and implications for tumorigenesis. Cold Spring Harbor Symposia On Quantitative Biology. 76: 313-24. PMID 22105806 DOI: 10.1101/Sqb.2011.76.010967 |
0.78 |
|
| 2011 |
Wang L, Brugge JS, Janes KA. Intersection of FOXO- and RUNX1-mediated gene expression programs in single breast epithelial cells during morphogenesis and tumor progression. Proceedings of the National Academy of Sciences of the United States of America. 108: E803-12. PMID 21873240 DOI: 10.1073/Pnas.1103423108 |
0.428 |
|
| 2011 |
Grassian AR, Metallo CM, Coloff JL, Stephanopoulos G, Brugge JS. Erk regulation of pyruvate dehydrogenase flux through PDK4 modulates cell proliferation. Genes & Development. 25: 1716-33. PMID 21852536 DOI: 10.1101/Gad.16771811 |
0.784 |
|
| 2011 |
Locasale JW, Grassian AR, Melman T, Lyssiotis CA, Mattaini KR, Bass AJ, Heffron G, Metallo CM, Muranen T, Sharfi H, Sasaki AT, Anastasiou D, Mullarky E, Vokes NI, Sasaki M, ... ... Brugge JS, et al. Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis. Nature Genetics. 43: 869-74. PMID 21804546 DOI: 10.1038/Ng.890 |
0.779 |
|
| 2011 |
Gallegos L, Ng MR, Brugge JS. The myosin-II-responsive focal adhesion proteome: a tour de force? Nature Cell Biology. 13: 344-6. PMID 21460805 DOI: 10.1038/Ncb2230 |
0.745 |
|
| 2011 |
Kim JH, Cho A, Yin H, Schafer DA, Mouneimne G, Simpson KJ, Nguyen KV, Brugge JS, Montell DJ. Psidin, a conserved protein that regulates protrusion dynamics and cell migration. Genes & Development. 25: 730-41. PMID 21406550 DOI: 10.1101/Gad.2028611 |
0.421 |
|
| 2011 |
Albeck JG, Brugge JS. Uncovering a tumor suppressor for triple-negative breast cancers. Cell. 144: 638-40. PMID 21376226 DOI: 10.1016/J.Cell.2011.02.030 |
0.336 |
|
| 2011 |
Krajcovic M, Johnson NB, Sun Q, Normand G, Hoover N, Yao E, Richardson AL, King RW, Cibas ES, Schnitt SJ, Brugge JS, Overholtzer M. A non-genetic route to aneuploidy in human cancers. Nature Cell Biology. 13: 324-30. PMID 21336303 DOI: 10.1038/Ncb2174 |
0.447 |
|
| 2011 |
Grassian AR, Schafer ZT, Brugge JS. ErbB2 stabilizes epidermal growth factor receptor (EGFR) expression via Erk and Sprouty2 in extracellular matrix-detached cells. The Journal of Biological Chemistry. 286: 79-90. PMID 20956544 DOI: 10.1074/Jbc.M110.169821 |
0.814 |
|
| 2011 |
Davidowitz R, Iwanicki M, Selfors L, Konecny G, Dering J, Slamon D, Brugge J. Abstract 4751: Identification of mechanism involved in mesothelial clearance by ovarian tumor spheroids Cancer Research. 71: 4751-4751. DOI: 10.1158/1538-7445.Am2011-4751 |
0.824 |
|
| 2011 |
Grassian AR, Metallo CM, Stephanopoulos G, Brugge JS. Abstract 2802: Evaluation of metabolic changes induced by loss of extracellular matrix attachment using 13C Flux analysis Cancer Research. 71: 2802-2802. DOI: 10.1158/1538-7445.Am2011-2802 |
0.76 |
|
| 2011 |
Muranen TE, Morales F, Selfors L, Worster D, Albeck J, Gao S, Iwanicki M, Mills G, Brugge JS. Abstract 1540: Targeting PI3K/mTOR inhibitor induced survival programs abrogates resistance to cell death in ECM-attached cancer cells Cancer Research. 71: 1540-1540. DOI: 10.1158/1538-7445.Am2011-1540 |
0.455 |
|
| 2011 |
Brugge J. Rab25 Mediates Integrin Recycling for Tumor Cell Migration in 3D Developmental Cell. 21: e1. DOI: 10.1016/J.Devcel.2011.10.024 |
0.382 |
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| 2011 |
Besser A, Rosa Ng M, Brugge J, Danuser G. Quantifying Mechanical Interactions between Cells in Small Clusters Biophysical Journal. 100: 190a. DOI: 10.1016/J.Bpj.2010.12.1255 |
0.411 |
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| 2010 |
Harrison SC, Brugge JS. Mechanistic biology in the next quarter century. Molecular Biology of the Cell. 21: 3799-800. PMID 21079017 DOI: 10.1091/Mbc.E10-05-0441 |
0.395 |
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| 2010 |
Knowlton ML, Selfors LM, Wrobel CN, Gu TL, Ballif BA, Gygi SP, Polakiewicz R, Brugge JS. Profiling Y561-dependent and -independent substrates of CSF-1R in epithelial cells. Plos One. 5: e13587. PMID 21049007 DOI: 10.1371/Journal.Pone.0013587 |
0.78 |
|
| 2010 |
Irie HY, Shrestha Y, Selfors LM, Frye F, Iida N, Wang Z, Zou L, Yao J, Lu Y, Epstein CB, Natesan S, Richardson AL, Polyak K, Mills GB, Hahn WC, ... Brugge JS, et al. PTK6 regulates IGF-1-induced anchorage-independent survival. Plos One. 5: e11729. PMID 20668531 DOI: 10.1371/Journal.Pone.0011729 |
0.445 |
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| 2010 |
Tushir JS, Clancy J, Warren A, Wrobel C, Brugge JS, D'Souza-Schorey C. Unregulated ARF6 activation in epithelial cysts generates hyperactive signaling endosomes and disrupts morphogenesis. Molecular Biology of the Cell. 21: 2355-66. PMID 20462959 DOI: 10.1091/Mbc.E09-09-0824 |
0.399 |
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| 2010 |
Zhou W, Hur W, McDermott U, Dutt A, Xian W, Ficarro SB, Zhang J, Sharma SV, Brugge J, Meyerson M, Settleman J, Gray NS. A structure-guided approach to creating covalent FGFR inhibitors. Chemistry & Biology. 17: 285-95. PMID 20338520 DOI: 10.1016/J.Chembiol.2010.02.007 |
0.373 |
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| 2010 |
Janes KA, Wang CC, Holmberg KJ, Cabral K, Brugge JS. Identifying single-cell molecular programs by stochastic profiling. Nature Methods. 7: 311-7. PMID 20228812 DOI: 10.1038/Nmeth.1442 |
0.428 |
|
| 2010 |
Mazzone M, Selfors LM, Albeck J, Overholtzer M, Sale S, Carroll DL, Pandya D, Lu Y, Mills GB, Aster JC, Artavanis-Tsakonas S, Brugge JS. Dose-dependent induction of distinct phenotypic responses to Notch pathway activation in mammary epithelial cells. Proceedings of the National Academy of Sciences of the United States of America. 107: 5012-7. PMID 20194747 DOI: 10.1073/Pnas.1000896107 |
0.434 |
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| 2010 |
Wolfer A, Wittner BS, Irimia D, Flavin RJ, Lupien M, Gunawardane RN, Meyer CA, Lightcap ES, Tamayo P, Mesirov JP, Liu XS, Shioda T, Toner M, Loda M, Brown M, ... Brugge JS, et al. MYC regulation of a "poor-prognosis" metastatic cancer cell state. Proceedings of the National Academy of Sciences of the United States of America. 107: 3698-703. PMID 20133671 DOI: 10.1073/Pnas.0914203107 |
0.43 |
|
| 2010 |
Wolfer A, Wittner BS, Irimia D, Flavin RJ, Lupien M, Gunawardane RN, Meyer CA, Lightcap ES, Tamayo P, Mesirov JP, Liu XS, Shioda T, Toner M, Loda M, Brown M, ... Brugge JS, et al. Abstract 3300: MYC regulation of a “poor prognosis” metastatic cancer cell state Cancer Research. 70: 3300-3300. DOI: 10.1158/1538-7445.Am10-3300 |
0.418 |
|
| 2009 |
Muller PA, Caswell PT, Doyle B, Iwanicki MP, Tan EH, Karim S, Lukashchuk N, Gillespie DA, Ludwig RL, Gosselin P, Cromer A, Brugge JS, Sansom OJ, Norman JC, Vousden KH. Mutant p53 drives invasion by promoting integrin recycling. Cell. 139: 1327-41. PMID 20064378 DOI: 10.1016/J.Cell.2009.11.026 |
0.374 |
|
| 2009 |
Leung CT, Brugge JS. Tumor self-seeding: bidirectional flow of tumor cells. Cell. 139: 1226-8. PMID 20064369 DOI: 10.1016/J.Cell.2009.12.013 |
0.361 |
|
| 2009 |
Ng MR, Brugge JS. A stiff blow from the stroma: collagen crosslinking drives tumor progression. Cancer Cell. 16: 455-7. PMID 19962663 DOI: 10.1016/J.Ccr.2009.11.013 |
0.773 |
|
| 2009 |
Iwanicki MP, Brugge JS. Transcriptional regulation of metastatic [Id]entity by KLF17. Genome Biology. 10: 244. PMID 19951400 DOI: 10.1186/Gb-2009-10-11-244 |
0.308 |
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| 2009 |
Zhang J, Ji JY, Yu M, Overholtzer M, Smolen GA, Wang R, Brugge JS, Dyson NJ, Haber DA. YAP-dependent induction of amphiregulin identifies a non-cell-autonomous component of the Hippo pathway. Nature Cell Biology. 11: 1444-50. PMID 19935651 DOI: 10.1038/Ncb1993 |
0.491 |
|
| 2009 |
Schafer ZT, Grassian AR, Song L, Jiang Z, Gerhart-Hines Z, Irie HY, Gao S, Puigserver P, Brugge JS. Antioxidant and oncogene rescue of metabolic defects caused by loss of matrix attachment. Nature. 461: 109-13. PMID 19693011 DOI: 10.1038/Nature08268 |
0.804 |
|
| 2009 |
Mouneimne G, Brugge JS. YB-1 translational control of epithelial-mesenchyme transition. Cancer Cell. 15: 357-9. PMID 19411064 DOI: 10.1016/J.Ccr.2009.04.006 |
0.343 |
|
| 2009 |
Xian W, Pappas L, Pandya D, Selfors LM, Derksen PW, de Bruin M, Gray NS, Jonkers J, Rosen JM, Brugge JS. Fibroblast growth factor receptor 1-transformed mammary epithelial cells are dependent on RSK activity for growth and survival. Cancer Research. 69: 2244-51. PMID 19258500 DOI: 10.1158/0008-5472.Can-08-3398 |
0.46 |
|
| 2009 |
Zhang J, Ji J, Yi M, Overholtzer M, Smolen GA, Wang R, Brugge JS, Dyson NJ, Haber DA. Abstract LB-228: YAP-dependent induction of amphiregulin identifies a non-cell-autonomous component of the Hippo pathway Cancer Research. 70. DOI: 10.1158/1538-7445.Am10-Lb-228 |
0.483 |
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| 2009 |
Schafer Z, Grassian A, Song L, Mailleux A, Schmelzle T, Irie Y, Gao G, Overholtzer M, Jiang Z, Gerhart‐Hines Z, Puigsever P, Brugge JS. Abstract IA-13: Mechanisms regulating anchorage independent survival Cancer Research. 69. DOI: 10.1158/0008-5472.Fbcr09-Ia-13 |
0.73 |
|
| 2009 |
Xian W, Pappas L, Pandya D, Selfors LM, Derksen PW, De Bruin M, Gray NS, Jonkers J, Rosen JM, Brugge JS. Fibroblast growth factor receptor 1-transformed mammary epithelial cells are dependent on RSK activity for growth and survival (Cancer Research (2009) 69 (2244-2251)) Cancer Research. 69: 6366. DOI: 10.1158/0008-5472.Can-69-15-Cor1 |
0.36 |
|
| 2008 |
Simpson KJ, Selfors LM, Bui J, Reynolds A, Leake D, Khvorova A, Brugge JS. Identification of genes that regulate epithelial cell migration using an siRNA screening approach. Nature Cell Biology. 10: 1027-38. PMID 19160483 DOI: 10.1038/Ncb1762 |
0.444 |
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| 2008 |
Overholtzer M, Brugge JS. The cell biology of cell-in-cell structures. Nature Reviews. Molecular Cell Biology. 9: 796-809. PMID 18784728 DOI: 10.1038/Nrm2504 |
0.423 |
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| 2008 |
Melani M, Simpson KJ, Brugge JS, Montell D. Regulation of cell adhesion and collective cell migration by hindsight and its human homolog RREB1. Current Biology : Cb. 18: 532-7. PMID 18394891 DOI: 10.1016/J.Cub.2008.03.024 |
0.468 |
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| 2008 |
Mailleux AA, Overholtzer M, Brugge JS. Lumen formation during mammary epithelial morphogenesis: insights from in vitro and in vivo models. Cell Cycle (Georgetown, Tex.). 7: 57-62. PMID 18196964 DOI: 10.4161/Cc.7.1.5150 |
0.394 |
|
| 2007 |
Schafer ZT, Brugge JS. IL-6 involvement in epithelial cancers. The Journal of Clinical Investigation. 117: 3660-3. PMID 18060028 DOI: 10.1172/Jci34237 |
0.628 |
|
| 2007 |
Overholtzer M, Mailleux AA, Mouneimne G, Normand G, Schnitt SJ, King RW, Cibas ES, Brugge JS. A nonapoptotic cell death process, entosis, that occurs by cell-in-cell invasion. Cell. 131: 966-79. PMID 18045538 DOI: 10.1016/J.Cell.2007.10.040 |
0.466 |
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| 2007 |
Fischbach C, Chen R, Matsumoto T, Schmelzle T, Brugge JS, Polverini PJ, Mooney DJ. Engineering tumors with 3D scaffolds. Nature Methods. 4: 855-60. PMID 17767164 DOI: 10.1038/Nmeth1085 |
0.371 |
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| 2007 |
Mouneimne G, Brugge JS. Tensins: a new switch in cell migration. Developmental Cell. 13: 317-9. PMID 17765673 DOI: 10.1016/J.Devcel.2007.08.010 |
0.425 |
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| 2007 |
Brugge J, Hung MC, Mills GB. A new mutational AKTivation in the PI3K pathway. Cancer Cell. 12: 104-7. PMID 17692802 DOI: 10.1016/J.Ccr.2007.07.014 |
0.319 |
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| 2007 |
Miller-Jensen K, Janes KA, Brugge JS, Lauffenburger DA. Common effector processing mediates cell-specific responses to stimuli. Nature. 448: 604-8. PMID 17637676 DOI: 10.1038/Nature06001 |
0.445 |
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| 2007 |
Schmelzle T, Mailleux AA, Overholtzer M, Carroll JS, Solimini NL, Lightcap ES, Veiby OP, Brugge JS. Functional role and oncogene-regulated expression of the BH3-only factor Bmf in mammary epithelial anoikis and morphogenesis. Proceedings of the National Academy of Sciences of the United States of America. 104: 3787-92. PMID 17360431 DOI: 10.1073/Pnas.0700115104 |
0.48 |
|
| 2007 |
Carroll DK, Brugge JS, Attardi LD. p63, cell adhesion and survival Cell Cycle. 6: 255-261. PMID 17297292 DOI: 10.4161/Cc.6.3.3799 |
0.36 |
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| 2007 |
Mailleux AA, Overholtzer M, Schmelzle T, Bouillet P, Strasser A, Brugge JS. BIM regulates apoptosis during mammary ductal morphogenesis, and its absence reveals alternative cell death mechanisms. Developmental Cell. 12: 221-34. PMID 17276340 DOI: 10.1016/J.Devcel.2006.12.003 |
0.42 |
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| 2006 |
Walker SJ, Brugge JS. SePARating polarity and proliferation in ErbB2 oncogenesis. Nature Cell Biology. 8: 1220-2. PMID 17077856 DOI: 10.1038/Ncb1106-1220 |
0.345 |
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| 2006 |
Overholtzer M, Zhang J, Smolen GA, Muir B, Li W, Sgroi DC, Deng CX, Brugge JS, Haber DA. Transforming properties of YAP, a candidate oncogene on the chromosome 11q22 amplicon. Proceedings of the National Academy of Sciences of the United States of America. 103: 12405-10. PMID 16894141 DOI: 10.1073/Pnas.0605579103 |
0.411 |
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| 2006 |
Carroll DK, Carroll JS, Leong CO, Cheng F, Brown M, Mills AA, Brugge JS, Ellisen LW. p63 regulates an adhesion programme and cell survival in epithelial cells. Nature Cell Biology. 8: 551-61. PMID 16715076 DOI: 10.1038/Ncb1420 |
0.42 |
|
| 2006 |
Wilsbacher JL, Moores SL, Brugge JS. An active form of Vav1 induces migration of mammary epithelial cells by stimulating secretion of an epidermal growth factor receptor ligand. Cell Communication and Signaling : Ccs. 4: 5. PMID 16709244 DOI: 10.1186/1478-811X-4-5 |
0.405 |
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| 2006 |
Hall AB, Gakidis MA, Glogauer M, Wilsbacher JL, Gao S, Swat W, Brugge JS. Requirements for Vav guanine nucleotide exchange factors and Rho GTPases in FcgammaR- and complement-mediated phagocytosis. Immunity. 24: 305-16. PMID 16546099 DOI: 10.1016/J.Immuni.2006.02.005 |
0.342 |
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| 2006 |
Witt AE, Hines LM, Collins NL, Hu Y, Gunawardane RN, Moreira D, Raphael J, Jepson D, Koundinya M, Rolfs A, Taron B, Isakoff SJ, Brugge JS, LaBaer J. Functional proteomics approach to investigate the biological activities of cDNAs implicated in breast cancer. Journal of Proteome Research. 5: 599-610. PMID 16512675 DOI: 10.1021/Pr050395R |
0.686 |
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| 2005 |
Irie HY, Pearline RV, Grueneberg D, Hsia M, Ravichandran P, Kothari N, Natesan S, Brugge JS. Distinct roles of Akt1 and Akt2 in regulating cell migration and epithelial-mesenchymal transition. The Journal of Cell Biology. 171: 1023-34. PMID 16365168 DOI: 10.1083/Jcb.200505087 |
0.441 |
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| 2005 |
Gunawardane RN, Sgroi DC, Wrobel CN, Koh E, Daley GQ, Brugge JS. Novel role for PDEF in epithelial cell migration and invasion. Cancer Research. 65: 11572-80. PMID 16357167 DOI: 10.1158/0008-5472.Can-05-1196 |
0.452 |
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| 2005 |
Isakoff SJ, Engelman JA, Irie HY, Luo J, Brachmann SM, Pearline RV, Cantley LC, Brugge JS. Breast cancer-associated PIK3CA mutations are oncogenic in mammary epithelial cells. Cancer Research. 65: 10992-1000. PMID 16322248 DOI: 10.1158/0008-5472.Can-05-2612 |
0.402 |
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| 2005 |
Debnath J, Brugge JS. Modelling glandular epithelial cancers in three-dimensional cultures. Nature Reviews. Cancer. 5: 675-88. PMID 16148884 DOI: 10.1038/Nrc1695 |
0.327 |
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| 2005 |
Yan SR, Joseph RR, Rosen K, Reginato MJ, Jackson A, Allaire N, Brugge JS, Jobin C, Stadnyk AW. Activation of NF-kappaB following detachment delays apoptosis in intestinal epithelial cells. Oncogene. 24: 6482-91. PMID 16007176 DOI: 10.1038/Sj.Onc.1208810 |
0.697 |
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| 2005 |
Collins NL, Reginato MJ, Paulus JK, Sgroi DC, Labaer J, Brugge JS. G1/S cell cycle arrest provides anoikis resistance through Erk-mediated Bim suppression. Molecular and Cellular Biology. 25: 5282-91. PMID 15923641 DOI: 10.1128/Mcb.25.12.5282-5291.2005 |
0.697 |
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| 2005 |
Reginato MJ, Mills KR, Becker EB, Lynch DK, Bonni A, Muthuswamy SK, Brugge JS. Bim regulation of lumen formation in cultured mammary epithelial acini is targeted by oncogenes. Molecular and Cellular Biology. 25: 4591-601. PMID 15899862 DOI: 10.1128/Mcb.25.11.4591-4601.2005 |
0.794 |
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| 2004 |
Shaw KR, Wrobel CN, Brugge JS. Use of three-dimensional basement membrane cultures to model oncogene-induced changes in mammary epithelial morphogenesis. Journal of Mammary Gland Biology and Neoplasia. 9: 297-310. PMID 15838601 DOI: 10.1007/S10911-004-1402-Z |
0.431 |
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| 2004 |
Bill HM, Knudsen B, Moores SL, Muthuswamy SK, Rao VR, Brugge JS, Miranti CK. Epidermal growth factor receptor-dependent regulation of integrin-mediated signaling and cell cycle entry in epithelial cells. Molecular and Cellular Biology. 24: 8586-99. PMID 15367678 DOI: 10.1128/Mcb.24.19.8586-8599.2004 |
0.474 |
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| 2004 |
Ma XJ, Wang Z, Ryan PD, Isakoff SJ, Barmettler A, Fuller A, Muir B, Mohapatra G, Salunga R, Tuggle JT, Tran Y, Tran D, Tassin A, Amon P, Wang W, ... ... Brugge J, et al. A two-gene expression ratio predicts clinical outcome in breast cancer patients treated with tamoxifen. Cancer Cell. 5: 607-16. PMID 15193263 DOI: 10.1016/J.Ccr.2004.05.015 |
0.342 |
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| 2004 |
Wrobel CN, Debnath J, Lin E, Beausoleil S, Roussel MF, Brugge JS. Autocrine CSF-1R activation promotes Src-dependent disruption of mammary epithelial architecture. The Journal of Cell Biology. 165: 263-73. PMID 15117969 DOI: 10.1083/Jcb.200309102 |
0.371 |
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| 2004 |
Seton-Rogers SE, Brugge JS. ErbB2 and TGF-beta: a cooperative role in mammary tumor progression? Cell Cycle (Georgetown, Tex.). 3: 597-600. PMID 15107620 DOI: 10.4161/Cc.3.5.886 |
0.571 |
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| 2004 |
Martin SS, Ridgeway AG, Pinkas J, Lu Y, Reginato MJ, Koh EY, Michelman M, Daley GQ, Brugge JS, Leder P. A cytoskeleton-based functional genetic screen identifies Bcl-xL as an enhancer of metastasis, but not primary tumor growth. Oncogene. 23: 4641-5. PMID 15064711 DOI: 10.1038/Sj.Onc.1207595 |
0.725 |
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| 2004 |
Mills KR, Reginato M, Debnath J, Queenan B, Brugge JS. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is required for induction of autophagy during lumen formation in vitro. Proceedings of the National Academy of Sciences of the United States of America. 101: 3438-43. PMID 14993595 DOI: 10.1073/Pnas.0400443101 |
0.791 |
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| 2004 |
Seton-Rogers SE, Lu Y, Hines LM, Koundinya M, LaBaer J, Muthuswamy SK, Brugge JS. Cooperation of the ErbB2 receptor and transforming growth factor beta in induction of migration and invasion in mammary epithelial cells. Proceedings of the National Academy of Sciences of the United States of America. 101: 1257-62. PMID 14739340 DOI: 10.1073/Pnas.0308090100 |
0.605 |
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| 2004 |
Seton-Rogers SE, Brugge JS. ErbB2 and TGF-β: A cooperative role in mammary tumor progression? Cell Cycle. 3: 597-600. |
0.521 |
|
| 2003 |
Fujikawa K, Miletic AV, Alt FW, Faccio R, Brown T, Hoog J, Fredericks J, Nishi S, Mildiner S, Moores SL, Brugge J, Rosen FS, Swat W. Vav1/2/3-null mice define an essential role for Vav family proteins in lymphocyte development and activation but a differential requirement in MAPK signaling in T and B cells. The Journal of Experimental Medicine. 198: 1595-608. PMID 14623913 DOI: 10.1084/Jem.20030874 |
0.357 |
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| 2003 |
Debnath J, Walker SJ, Brugge JS. Akt activation disrupts mammary acinar architecture and enhances proliferation in an mTOR-dependent manner. The Journal of Cell Biology. 163: 315-26. PMID 14568991 DOI: 10.1083/Jcb.200304159 |
0.437 |
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| 2003 |
Gozani O, Karuman P, Jones DR, Ivanov D, Cha J, Lugovskoy AA, Baird CL, Zhu H, Field SJ, Lessnick SL, Villasenor J, Mehrotra B, Chen J, Rao VR, Brugge JS, et al. The PHD finger of the chromatin-associated protein ING2 functions as a nuclear phosphoinositide receptor. Cell. 114: 99-111. PMID 12859901 DOI: 10.1016/S0092-8674(03)00480-X |
0.315 |
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| 2003 |
Reginato MJ, Mills KR, Paulus JK, Lynch DK, Sgroi DC, Debnath J, Muthuswamy SK, Brugge JS. Integrins and EGFR coordinately regulate the pro-apoptotic protein Bim to prevent anoikis. Nature Cell Biology. 5: 733-40. PMID 12844146 DOI: 10.1038/Ncb1026 |
0.788 |
|
| 2003 |
Debnath J, Muthuswamy SK, Brugge JS. Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures. Methods (San Diego, Calif.). 30: 256-68. PMID 12798140 DOI: 10.1016/S1046-2023(03)00032-X |
0.352 |
|
| 2002 |
Debnath J, Mills KR, Collins NL, Reginato MJ, Muthuswamy SK, Brugge JS. The role of apoptosis in creating and maintaining luminal space within normal and oncogene-expressing mammary acini. Cell. 111: 29-40. PMID 12372298 DOI: 10.1016/S0092-8674(02)01001-2 |
0.801 |
|
| 2002 |
Chaudhary A, Brugge JS, Cooper JA. Direct phosphorylation of focal adhesion kinase by c-Src: evidence using a modified nucleotide pocket kinase and ATP analog. Biochemical and Biophysical Research Communications. 294: 293-300. PMID 12051709 DOI: 10.1016/S0006-291X(02)00475-8 |
0.345 |
|
| 2002 |
Miranti CK, Brugge JS. Sensing the environment: a historical perspective on integrin signal transduction. Nature Cell Biology. 4: E83-90. PMID 11944041 DOI: 10.1038/Ncb0402-E83 |
0.408 |
|
| 2002 |
Obergfell A, Eto K, Mocsai A, Buensuceso C, Moores SL, Brugge JS, Lowell CA, Shattil SJ. Coordinate interactions of Csk, Src, and Syk kinases with [alpha]IIb[beta]3 initiate integrin signaling to the cytoskeleton. The Journal of Cell Biology. 157: 265-75. PMID 11940607 DOI: 10.1083/Jcb.200112113 |
0.357 |
|
| 2001 |
Woodside DG, Obergfell A, Leng L, Wilsbacher JL, Miranti CK, Brugge JS, Shattil SJ, Ginsberg MH. Activation of Syk protein tyrosine kinase through interaction with integrin β cytoplasmic domains Current Biology. 11: 1799-1804. PMID 11719224 DOI: 10.1016/S0960-9822(01)00565-6 |
0.34 |
|
| 2001 |
Muthuswamy SK, Li D, Lelievre S, Bissell MJ, Brugge JS. ErbB2, but not ErbB1, reinitiates proliferation and induces luminal repopulation in epithelial acini Nature Cell Biology. 3: 785-792. PMID 11533657 DOI: 10.1038/Ncb0901-785 |
0.401 |
|
| 2000 |
Moores SL, Selfors LM, Fredericks J, Breit T, Fujikawa K, Alt FW, Brugge JS, Swat W. Vav family proteins couple to diverse cell surface receptors. Molecular and Cellular Biology. 20: 6364-73. PMID 10938113 DOI: 10.1128/Mcb.20.17.6364-6373.2000 |
0.398 |
|
| 2000 |
Chaudhary A, King WG, Mattaliano MD, Frost JA, Diaz B, Morrison DK, Cobb MH, Marshall MS, Brugge JS. Phosphatidylinositol 3-kinase regulates Raf1 through Pak phosphorylation of serine 338. Current Biology : Cb. 10: 551-4. PMID 10801448 DOI: 10.1016/S0960-9822(00)00475-9 |
0.322 |
|
| 1999 |
Rao VR, Corradetti MN, Chen J, Peng J, Yuan J, Prestwich GD, Brugge JS. Expression cloning of protein targets for 3-phosphorylated phosphoinositides Journal of Biological Chemistry. 274: 37893-37900. PMID 10608855 DOI: 10.1074/Jbc.274.53.37893 |
0.325 |
|
| 1999 |
Muthuswamy SK, Gilman M, Brugge JS. Controlled dimerization of ErbB receptors provides evidence for differential signaling by homo- and heterodimers. Molecular and Cellular Biology. 19: 6845-57. PMID 10490623 DOI: 10.1128/Mcb.19.10.6845 |
0.387 |
|
| 1999 |
Miranti CK, Ohno S, Brugge JS. Protein kinase C regulates integrin-induced activation of the extracellular regulated kinase pathway upstream of Shc Journal of Biological Chemistry. 274: 10571-10581. PMID 10187852 DOI: 10.1074/Jbc.274.15.10571 |
0.397 |
|
| 1999 |
Lee RJ, Albanese C, Stenger RJ, Watanabe G, Inghirami G, Haines GK, Webster M, Muller WJ, Brugge JS, Davis RJ, Pestell RG. pp60(v-src) induction of cyclin D1 requires collaborative interactions between the extracellular signal-regulated kinase, p38, and Jun kinase pathways: A role for cAMP response element-binding protein and activating transcription factor-2 in pp60(v-src) signaling in breast cancer cells Journal of Biological Chemistry. 274: 7341-7350. PMID 10066798 DOI: 10.1074/Jbc.274.11.7341 |
0.392 |
|
| 1999 |
Brugge JS, McCormick F. Cell regulation intracellular networking Current Opinion in Cell Biology. 11: 173-176. DOI: 10.1016/S0955-0674(99)80022-2 |
0.333 |
|
| 1998 |
Miranti CK, Leng L, Maschberger P, Brugge JS, Shattil SJ. Identification of a novel integrin signaling pathway involving the kinase Syk and the guanine nucleotide exchange factor Vav1 Current Biology. 8: 1289-1299. PMID 9843681 DOI: 10.1016/S0960-9822(07)00559-3 |
0.404 |
|
| 1998 |
Brugge JS. Casting light on focal adhesions Nature Genetics. 19: 309-311. PMID 9697683 DOI: 10.1038/1189 |
0.333 |
|
| 1998 |
Clark EA, King WG, Brugge JS, Symons M, Hynes RO. Integrin-mediated signals regulated by members of the rho family of gtpases Journal of Cell Biology. 142: 573-586. PMID 9679153 DOI: 10.1083/Jcb.142.2.573 |
0.402 |
|
| 1997 |
Thomas SM, Brugge JS. Cellular functions regulated by SRC family kinases Annual Review of Cell and Developmental Biology. 13: 513-609. PMID 9442882 DOI: 10.1146/Annurev.Cellbio.13.1.513 |
0.332 |
|
| 1997 |
Gao J, Zoller KE, Ginsberg MH, Brugge JS, Shattil SJ. Regulation of the pp72(syk) protein tyrosine kinase by platelet integrin α(IIb)β3 Embo Journal. 16: 6414-6425. PMID 9351824 DOI: 10.1093/Emboj/16.21.6414 |
0.311 |
|
| 1997 |
King WG, Mattaliano MD, Chan TO, Tsichlis PN, Brugge JS. Phosphatidylinositol 3-kinase is required for integrin-stimulated AKT and Raf-1/mitogen-activated protein kinase pathway activation. Molecular and Cellular Biology. 17: 4406-18. PMID 9234699 DOI: 10.1128/Mcb.17.8.4406 |
0.335 |
|
| 1997 |
Bolen JB, Brugge JS. Leukocyte protein tyrosine kinases: Potential targets for drug discovery Annual Review of Immunology. 15: 371-404. PMID 9143693 DOI: 10.1146/Annurev.Immunol.15.1.371 |
0.354 |
|
| 1997 |
Brugge JS, Clark EA, Shattil SJ. Protein Tyrosine Phosphorylation in Platelets Advances in Molecular and Cell Biology. 18: 335-352. DOI: 10.1016/S1569-2558(08)60420-8 |
0.326 |
|
| 1996 |
Cichowski K, Brugge JS, Brass LF. Thrombin receptor activation and integrin engagement stimulate tyrosine phosphorylation of the proto-oncogene product, p95vav, in platelets Journal of Biological Chemistry. 271: 7544-7550. PMID 8631786 DOI: 10.1074/Jbc.271.13.7544 |
0.354 |
|
| 1995 |
Rusanescu G, Qi H, Thomas SM, Brugge JS, Halegoua S. Calcium influx induces neurite growth through a Src-Ras signaling cassette Neuron. 15: 1415-1425. PMID 8845164 DOI: 10.1016/0896-6273(95)90019-5 |
0.312 |
|
| 1995 |
Clark EA, Brugge JS. Integrins and sign transduction pathways: The road taken Science. 268: 233-239. PMID 7716514 DOI: 10.1126/Science.7716514 |
0.396 |
|
| 1995 |
Mukhopadhyay D, Tsiokas L, Zhou XM, Foster D, Brugge JS, Sukhatme VP. Hypoxic induction of human vascular endothelial growth factor expression through c-Src activation Nature. 375: 577-581. PMID 7540725 DOI: 10.1038/375577A0 |
0.329 |
|
| 1995 |
Shiue L, Zoller MJ, Brugge JS. Syk is activated by phosphotyrosine-containing peptides representing the tyrosine-based activation motifs of the high affinity receptor for IgE Journal of Biological Chemistry. 270: 10498-10502. PMID 7537732 DOI: 10.1074/Jbc.270.18.10498 |
0.342 |
|
| 1995 |
Rivera VM, Brugge JS. Clustering of Syk is sufficient to induce tyrosine phosphorylation and release of allergic mediators from rat basophilic leukemia cells Molecular and Cellular Biology. 15: 1582-1590. PMID 7532280 DOI: 10.1128/Mcb.15.3.1582 |
0.388 |
|
| 1994 |
Clark EA, Shattil SJ, Brugge JS. Regulation of protein tyrosine kinases in platelets Trends in Biochemical Sciences. 19: 464-469. PMID 7855888 DOI: 10.1016/0968-0004(94)90131-7 |
0.334 |
|
| 1994 |
Shattil SJ, Ginsberg MH, Brugge JS. Adhesive signaling in platelets Current Opinion in Cell Biology. 6: 695-704. PMID 7530462 DOI: 10.1016/0955-0674(94)90096-5 |
0.306 |
|
| 1994 |
Weng Z, Thomas SM, Rickles RJ, Taylor JA, Brauer AW, Seidel-Dugan C, Michael WM, Dreyfuss G, Brugge JS. Identification of Src, Fyn, and Lyn SH3-binding proteins: implications for a function of SH3 domains. Molecular and Cellular Biology. 14: 4509-21. PMID 7516469 DOI: 10.1128/Mcb.14.7.4509 |
0.302 |
|
| 1993 |
Huang MM, Lipfert L, Cunningham M, Brugge JS, Ginsberg MH, Shattil SJ. Adhesive ligand binding to integrin αIIbβ3 stimulates tyrosine phosphorylation of novel protein substrates before phosphorylation of pp125FAK Journal of Cell Biology. 122: 473-483. PMID 7686553 DOI: 10.1083/Jcb.122.2.473 |
0.315 |
|
| 1993 |
Clark EA, Brugge JS. Redistribution of activated pp60c-src to integrin-dependent cytoskeletal complexes in thrombin-stimulated platelets Molecular and Cellular Biology. 13: 1863-1871. PMID 7680100 DOI: 10.1128/Mcb.13.3.1863 |
0.324 |
|
| 1993 |
Clark EA, Brugge JS. Tyrosine phosphorylation in platelets. Potential roles in intracellular signal transduction Trends in Cardiovascular Medicine. 3: 218-227. DOI: 10.1016/1050-1738(93)90043-6 |
0.339 |
|
| 1992 |
Seidel-Dugan C, Meyer BE, Thomas SM, Brugge JS. Effects of SH2 and SH3 deletions on the functional activities of wild-type and transforming variants of c-Src Molecular and Cellular Biology. 12: 1835-1845. PMID 1549129 DOI: 10.1128/Mcb.12.4.1835 |
0.353 |
|
| 1992 |
Rozakis-Adcock M, McGlade J, Mbamalu G, Pelicci G, Daly R, Li W, Batzer A, Thomas S, Brugge J, Pelicci PG, Schlessinger J, Pawson T. Association of the Shc and Grb2/Sem5 SH2-containing proteins is implicated in activation of the Ras pathway by tyrosine kinases. Nature. 360: 689-92. PMID 1465135 DOI: 10.1038/360689A0 |
0.376 |
|
| 1992 |
Lipfert L, Haimovich B, Schaller MD, Cobb BS, Parsons JT, Brugge JS. Integrin-dependent phosphorylation and activation of the protein tyrosine kinase pp125FAK in platelets Journal of Cell Biology. 119: 905-912. PMID 1385445 DOI: 10.1083/Jcb.119.4.905 |
0.322 |
|
| 1992 |
Schmidt JW, Brugge JS, Nelson WJ. pp60src tyrosine kinase modulates P19 embryonal carcinoma cell fate by inhibiting neuronal but not epithelial differentiation Journal of Cell Biology. 116: 1019-1033. PMID 1370835 DOI: 10.1083/Jcb.116.4.1019 |
0.44 |
|
| 1992 |
Thomas SM, DeMarco M, D'Arcangelo G, Halegoua S, Brugge JS. Ras is essential for nerve growth factor- and phorbol ester-induced tyrosine phosphorylation of MAP kinases Cell. 68: 1031-1040. PMID 1312392 DOI: 10.1016/0092-8674(92)90075-N |
0.325 |
|
| 1991 |
Shattil SJ, Brugge JS. Protein tyrosine phosphorylation and the adhesive functions of platelets Current Opinion in Cell Biology. 3: 869-879. PMID 1931088 DOI: 10.1016/0955-0674(91)90062-4 |
0.422 |
|
| 1991 |
Lord KA, Abdollahi A, Thomas SM, DeMarco M, Brugge JS, Hoffman-Liebermann B, Liebermann DA. Leukemia inhibitory factor and interleukin-6 trigger the same immediate early response, including tyrosine phosphorylation, upon induction of myeloid leukemia differentiation. Molecular and Cellular Biology. 11: 4371-9. PMID 1908551 DOI: 10.1128/Mcb.11.9.4371 |
0.351 |
|
| 1991 |
Thomas SM, Hayes M, D'Arcangelo G, Armstrong RC, Meyer BE, Zilberstein A, Brugge JS, Halegoua S. Induction of neurite outgrowth by v-src mimics critical aspects of nerve growth factor-induced differentiation. Molecular and Cellular Biology. 11: 4739-50. PMID 1875950 DOI: 10.1128/Mcb.11.9.4739 |
0.362 |
|
| 1991 |
Thomas JE, Soriano P, Brugge JS. Phosphorylation of c-Src on tyrosine 527 by another protein tyrosine kinase Science. 254: 568-571. PMID 1719633 DOI: 10.1126/Science.1719633 |
0.362 |
|
| 1991 |
Kremer NE, D'Arcangelo G, Thomas SM, DeMarco M, Brugge JS, Halegoua S. Signal transduction by nerve growth factor and fibroblast growth factor in PC12 cells requires a sequence of Src and Ras actions Journal of Cell Biology. 115: 809-819. PMID 1717492 DOI: 10.1083/Jcb.115.3.809 |
0.329 |
|
| 1991 |
Huang MM, Bolen JB, Barnwell JW, Shattil SJ, Brugge JS. Membrane glycoprotein IV (CD36) is physically associated with the Fyn, Lyn, and Yes protein-tyrosine kinases in human platelets Proceedings of the National Academy of Sciences of the United States of America. 88: 7844-7848. PMID 1715582 DOI: 10.1073/Pnas.88.17.7844 |
0.362 |
|
| 1990 |
Filson AJ, Azarnia R, Beyer EC, Loewenstein WR, Brugge JS. Tyrosine phosphorylation of a gap junction protein correlates with inhibition of cell-to-cell communication Cell Growth &Amp; Differentiation : the Molecular Biology Journal of the American Association For Cancer Research. 1: 661-668. PMID 1963075 |
0.344 |
|
| 1989 |
Levy JB, Brugge JS. Biological and biochemical properties of the c-src+ gene product overexpressed in chicken embryo fibroblasts Molecular and Cellular Biology. 9: 3332-3341. PMID 2477684 DOI: 10.1128/Mcb.9.8.3332 |
0.368 |
|
| 1989 |
Nement SP, Fox LG, DeMarco M, Brugge JS. Deletions within the amino-terminal half of the c-src gene product that alter the functional activity of the protein Molecular and Cellular Biology. 9: 1109-1119. PMID 2471059 DOI: 10.1128/Mcb.9.3.1109 |
0.343 |
|
| 1989 |
Golden A, Brugge JS. Thrombin treatment induces rapid changes in tyrosine phosphorylation in platelets Proceedings of the National Academy of Sciences of the United States of America. 86: 901-905. PMID 2464830 DOI: 10.1073/Pnas.86.3.901 |
0.304 |
|
| 1988 |
Schuh SM, Brugge JS. Investigation of factors that influence phosphorylation of pp60c-src on tyrosine 527. Molecular and Cellular Biology. 8: 2465-71. PMID 2457151 DOI: 10.1128/Mcb.8.6.2465 |
0.324 |
|
| 1987 |
Brugge JS, Jarosik G, Andersen J, Queral-Lustig A, Fedor-Chaiken M, Broach JR. Expression of Rous sarcoma virus transforming protein pp60v-src in Saccharomyces cerevisiae cells Molecular and Cellular Biology. 7: 2180-2187. PMID 3037349 DOI: 10.1128/Mcb.7.6.2180 |
0.415 |
|
| 1987 |
Brugge J, Cotton P, Lustig A, Yonemoto W, Lipsich L, Coussens P, Barrett JN, Nonner D, Keane RW. Characterization of the altered form of the c-src gene product in neuronal cells. Genes & Development. 1: 287-96. PMID 2445628 DOI: 10.1101/Gad.1.3.287 |
0.323 |
|
| 1987 |
Yonemoto W, Filson AJ, Queral-Lustig AE, Wang JY, Brugge JS. Detection of phosphotyrosine-containing proteins in polyomavirus middle tumor antigen-transformed cells after treatment with a phosphotyrosine phosphatase inhibitor Molecular and Cellular Biology. 7: 905-913. PMID 2434835 DOI: 10.1128/Mcb.7.2.905 |
0.389 |
|
| 1986 |
Brugge JS, Yonemoto W, Lustig A, Golden A. Investigations of the expression of the cellular src gene product Princess Takamatsu Symposia. 17: 241-249. PMID 3138228 |
0.32 |
|
| 1986 |
Lynch SA, Brugge JS, Levine JM. Induction of altered c-src product during neural differentiation of embryonal carcinoma cells Science. 234: 873-876. PMID 3095923 DOI: 10.1126/Science.3095923 |
0.381 |
|
| 1986 |
Golden A, Nemeth SP, Brugge JS. Blood platelets express high levels of the pp60(c-src)-specific tyrosine kinase activity Proceedings of the National Academy of Sciences of the United States of America. 83: 852-856. PMID 2419901 DOI: 10.1073/Pnas.83.4.852 |
0.349 |
|
| 1986 |
Brugge JS. Interaction of the Rous sarcoma virus protein pp60src with the cellular proteins pp50 and pp90 Current Topics in Microbiology and Immunology. 123: 1-22. PMID 2419040 DOI: 10.1007/978-3-642-70810-7_1 |
0.33 |
|
| 1985 |
Yonemoto W, Jarvis-Morar M, Brugge JS, Bolen JB, Israel MA. Tyrosine phosphorylation within the amino-terminal domain of pp60(c-src) molecules associated with polyoma virus middle-sized tumor antigen Proceedings of the National Academy of Sciences of the United States of America. 82: 4568-4572. PMID 3927285 DOI: 10.1073/Pnas.82.14.4568 |
0.357 |
|
| 1985 |
Brugge JS, Cotton PC, Queral AE, Barrett JN, Nonner D, Keane RW. Neurones express high levels of a structurally modified, activated form of pp60c-src. Nature. 316: 554-7. PMID 2412121 DOI: 10.1038/316554A0 |
0.305 |
|
| 1984 |
Keane RW, Lipsich LA, Brugge JS. Differentiation and transformation of neural plate cells Developmental Biology. 103: 38-52. PMID 6201407 DOI: 10.1016/0012-1606(84)90005-8 |
0.397 |
|
| 1984 |
Lipsich L, Brugge JS, Boettiger D. Expression of the Rous sarcoma virus src gene in avian macrophages fails to elicit transformed cell phenotype Molecular and Cellular Biology. 4: 1420-1424. PMID 6095071 DOI: 10.1128/Mcb.4.7.1420 |
0.348 |
|
| 1984 |
Bolen JB, Thiele CJ, Israel MA, Yonemoto W, Lipsich LA, Brugge JS. Enhancement of cellular src gene product associated tyrosyl kinase activity following polyoma virus infection and transformation Cell. 38: 767-777. PMID 6091900 DOI: 10.1016/0092-8674(84)90272-1 |
0.361 |
|
| 1983 |
Lipsich LA, Lewis AJ, Brugge JS. Isolation of monoclonal antibodies that recognize the transforming proteins of avian sarcoma viruses Journal of Virology. 48: 352-360. PMID 6312092 DOI: 10.1128/Jvi.48.2.352-360.1983 |
0.302 |
|
| 1983 |
Brugge J, Yonemoto W, Darrow D. Interaction between the Rous sarcoma virus transforming protein and two cellular phosphoproteins: analysis of the turnover and distribution of this complex. Molecular and Cellular Biology. 3: 9-19. PMID 6298609 DOI: 10.1128/Mcb.3.1.9 |
0.344 |
|
| 1983 |
Brugge JS, Chinkers M. Chapter 22. Tyrosine-Specific Protein Kinases Annual Reports in Medicinal Chemistry. 18: 213-224. DOI: 10.1016/S0065-7743(08)60777-0 |
0.348 |
|
| 1982 |
Brugge JS, Darrow D. Rous sarcoma virus-induced phosphorylation of a 50,000-molecular weight cellular protein Nature. 295: 250-253. PMID 6276761 DOI: 10.1038/295250A0 |
0.357 |
|
| 1981 |
Brugge JS, Erikson E, Erikson RL. The specific interaction of the Rous sarcoma virus transforming protein, pp60src, with two cellular proteins. Cell. 25: 363-72. PMID 6269742 DOI: 10.1016/0092-8674(81)90055-6 |
0.358 |
|
| 1980 |
Erikson RL, Purchio AF, Erikson E, Collett MS, Brugge JS. Molecular events in cells transformed by Rous Sarcoma virus. The Journal of Cell Biology. 87: 319-25. PMID 6253501 DOI: 10.1083/Jcb.87.2.319 |
0.387 |
|
| 1979 |
Lau AF, Krzyzek RA, Brugge JS, Collett MS, Erikson RL, Faras AJ. Expression of the src-gene product, pp60(src), in transformed and reverted mammalian cells infected with avian sarcoma virus Symposia On Quantitative Biology. 44: 1057-1064. PMID 6253180 DOI: 10.1101/Sqb.1980.044.01.114 |
0.32 |
|
| 1979 |
Erikson RL, Brugge JS, Erikson E, Collett MS. Studies on the structure and function of the avian sarcoma virus transforming gene product. Haematology and Blood Transfusion. 23: 261-9. PMID 232457 DOI: 10.1007/978-3-642-67057-2_32 |
0.359 |
|
| 1979 |
Lau AF, Krzyzek RA, Brugge JS, Erikson RL, Schollmeyer J, Faras AJ. Morphological revertants of an avian sarcoma virus-transformed mammalian cell line exhibit tumorigenicity and contain pp60(src) Proceedings of the National Academy of Sciences of the United States of America. 76: 3904-3908. PMID 226988 DOI: 10.1073/Pnas.76.8.3904 |
0.41 |
|
| 1979 |
Collett MS, Erikson E, Purchio AF, Brugge JS, Erikson RL. A normal cell protein similar in structure and function to the avian sarcoma virus transforming gene product. Proceedings of the National Academy of Sciences of the United States of America. 76: 3159-63. PMID 226956 DOI: 10.1073/Pnas.76.7.3159 |
0.428 |
|
| 1979 |
Collett MS, Brugge JS, Erikson RL, Lau AF, Krzyzek RA, Faras AJ. The src gene product of transformed and morphologically reverted ASV-infected mammalian cells Nature. 281: 195-198. PMID 225672 DOI: 10.1038/281195A0 |
0.407 |
|
| 1979 |
Brugge JS, Collett MS, Siddiqui A, Marczynska B, Deinhardt F, Erikson RL. Detection of the viral sarcoma gene product in cells infected with various strains of avian sarcoma virus and of a related protein in uninfected chicken cells Journal of Virology. 29: 1196-1203. PMID 221673 DOI: 10.1128/Jvi.29.3.1196-1203.1979 |
0.355 |
|
| 1978 |
Brugge JS, Steinbaugh PJ, Erikson RL. Characterization of the avian sarcoma virus protein p60src Virology. 91: 130-140. PMID 214955 DOI: 10.1016/0042-6822(78)90361-6 |
0.361 |
|
| 1978 |
Brugge J, Erikson E, Collett MS, Erikson RI. Peptide analysis of the transformation-specific antigen from avian sarcoma virus-transformed cells. Journal of Virology. 26: 773-82. PMID 209218 DOI: 10.1128/Jvi.26.3.773-782.1978 |
0.324 |
|
| 1978 |
Collett MS, Brugge JS, Erikson RL. Characterization of a normal avian cell protein related to the avian sarcoma virus transforming gene product Cell. 15: 1363-1369. PMID 83198 DOI: 10.1016/0092-8674(78)90061-2 |
0.418 |
|
| 1978 |
Brugge JS, Erikson E, Erikson RL. Antibody to virion structural proteins in mammals bearing avian sarcoma virus-induced tumors. Virology. 84: 429-33. PMID 74898 DOI: 10.1016/0042-6822(78)90259-3 |
0.308 |
|
| 1977 |
Brugge JS, Erikson RL. Identification of a transformation-specific antigen induced by an avian sarcoma virus Nature. 269: 346-348. PMID 198667 DOI: 10.1038/269346A0 |
0.341 |
|
| 1977 |
Vollet JJ, Brugge JS, Noonan CA, Butel JS. The role of SV40 gene A in the alteration of microfilaments in transformed cells Experimental Cell Research. 105: 119-126. PMID 190024 DOI: 10.1016/0014-4827(77)90157-4 |
0.382 |
|
| 1976 |
Noonan CA, Brugge JS, Butel JS. Characterization of simian cells transformed by temperature sensitive mutants of simian virus 40 Journal of Virology. 18: 1106-1119. PMID 178917 DOI: 10.1128/Jvi.18.3.1106-1119.1976 |
0.355 |
|
| 1975 |
Brugge JS, Butel JS. Role of simian virus 40 gene A function in maintenance of transformation Journal of Virology. 15: 619-635. PMID 163376 DOI: 10.1128/Jvi.15.3.619-635.1975 |
0.349 |
|
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