Year |
Citation |
Score |
2024 |
Churchill CC, Peterson CD, Kitto KF, Pflepsen KR, Belur LR, McIvor RS, Vulchanova L, Wilcox GL, Fairbanks CA. Adeno-associated virus-mediated gene transfer of arginine decarboxylase to the central nervous system prevents opioid analgesic tolerance. Frontiers in Pain Research (Lausanne, Switzerland). 4: 1269017. PMID 38405182 DOI: 10.3389/fpain.2023.1269017 |
0.655 |
|
2023 |
Clements BM, Peterson CD, Kitto KF, Caye LD, Wilcox GL, Fairbanks CA. Biodistribution of Agmatine to Brain and Spinal Cord after Systemic Delivery. The Journal of Pharmacology and Experimental Therapeutics. 387: 328-336. PMID 37770201 DOI: 10.1124/jpet.123.001828 |
0.629 |
|
2023 |
Peterson CD, Waataja JJ, Kitto KF, Erb S, Verma H, Schuster DJ, Churchill CC, Riedl MS, Belur LR, Wolf DA, McIvor RS, Vulchanova L, Wilcox GL, Fairbanks CA. Long-term reversal of chronic pain behavior in rodents through elevation of spinal agmatine. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 36710491 DOI: 10.1016/j.ymthe.2023.01.022 |
0.764 |
|
2021 |
Griffith JI, Kim M, Bruce DJ, Peterson CD, Kitto KF, Mohammad AS, Rathi S, Fairbanks CA, Wilcox GL, Elmquist WF. CNS Distribution of an Opioid Agonist Combination with Synergistic Activity. The Journal of Pharmacology and Experimental Therapeutics. PMID 34663676 DOI: 10.1124/jpet.121.000821 |
0.679 |
|
2021 |
Goracke-Postle CJ, Burkitt CC, Panoskaltsis-Mortari A, Ehrhardt M, Wilcox GL, Graupman P, Partington M, Symons FJ. Expression of and correlational patterns among neuroinflammatory, neuropeptide, and neuroendocrine molecules from cerebrospinal fluid in cerebral palsy. Bmc Neurology. 21: 384. PMID 34607558 DOI: 10.1186/s12883-021-02333-2 |
0.762 |
|
2021 |
Pflepsen KR, Peterson CD, Kitto KF, Riedl MS, McIvor RS, Wilcox GL, Vulchanova L, Fairbanks CA. Biodistribution of Adeno-Associated Virus Serotype 5 Viral Vectors Following Intrathecal Injection. Molecular Pharmaceutics. PMID 34460254 DOI: 10.1021/acs.molpharmaceut.1c00252 |
0.609 |
|
2021 |
Peterson CD, Kitto KF, Verma H, Pflepsen K, Delpire E, Wilcox GL, Fairbanks CA. Agmatine requires GluN2B-containing NMDA receptors to inhibit the development of neuropathic pain. Molecular Pain. 17: 17448069211029171. PMID 34210178 DOI: 10.1177/17448069211029171 |
0.671 |
|
2020 |
Akgűn E, Lunzer MM, Tian D, Ansonoff M, Pintar J, Hawkinson JE, Wilcox GL, Portoghese P. FBNTI, a DOR-selective antagonist that allosterically activates MOR within a MOR-DOR heteromer. Biochemistry. PMID 32930576 DOI: 10.1021/Acs.Biochem.0C00498 |
0.407 |
|
2020 |
Uhelski ML, Bruce D, Speltz R, Wilcox GL, Simone DA. Topical Application of Loperamide/Oxymorphindole, Mu and Delta Opioid Receptor Agonists, Reduces Sensitization of C-fiber Nociceptors that Possess Na1.8. Neuroscience. PMID 32858141 DOI: 10.1016/J.Neuroscience.2020.08.022 |
0.451 |
|
2020 |
Larson CM, Peterson CD, Kitto KF, Wilcox GL, Fairbanks CA. Sustained-release buprenorphine induces acute opioid tolerance in the mouse. European Journal of Pharmacology. 173330. PMID 32726653 DOI: 10.1016/J.Ejphar.2020.173330 |
0.665 |
|
2019 |
Larson CM, Wilcox GL, Fairbanks CA. Defining and Managing Pain in Stroke and Traumatic Brain Injury Research. Comparative Medicine. 69: 510-519. PMID 31896392 DOI: 10.30802/Aalas-Cm-19-000099 |
0.642 |
|
2019 |
Larson CM, Wilcox GL, Fairbanks CA. The Study of Pain in Rats and Mice. Comparative Medicine. PMID 31822322 DOI: 10.30802/Aalas-Cm-19-000062 |
0.64 |
|
2019 |
Shah R, Peterson C, Strom A, Dillenburg M, Finzel BC, Kitto KF, Fairbanks CA, Wilcox GL, Wagner CR. Inhibition of Hint1 Modulates Spinal Nociception and NMDA Evoked Behavior in Mice. Acs Chemical Neuroscience. PMID 31503445 DOI: 10.1021/Acschemneuro.9B00432 |
0.719 |
|
2019 |
Bruce DJ, Peterson CD, Kitto KF, Akgün E, Lazzaroni S, Portoghese PS, Fairbanks CA, Wilcox GL. Combination of a δ-opioid Receptor Agonist and Loperamide Produces Peripherally-mediated Analgesic Synergy in Mice. Anesthesiology. PMID 31343460 DOI: 10.1097/Aln.0000000000002840 |
0.714 |
|
2019 |
Krock E, Millecamps M, Anderson KM, Srivastava A, Reihsen TE, Hari P, Sun YR, Jang SH, Wilcox GL, Belani KG, Beebe DS, Ouellet J, Pinto MR, Kehl LJ, Haglund L, et al. Interleukin-8 as a therapeutic target for chronic low back pain: Upregulation in human cerebrospinal fluid and pre-clinical validation with chronic reparixin in the SPARC-null mouse model. Ebiomedicine. PMID 31047862 DOI: 10.1016/J.Ebiom.2019.04.032 |
0.349 |
|
2019 |
Peterson CD, Skorput AGJ, Kitto KF, Wilcox GL, Vulchanova L, Fairbanks CA. AAV-Mediated Gene Delivery to the Spinal Cord by Intrathecal Injection. Methods in Molecular Biology (Clifton, N.J.). 1950: 199-207. PMID 30783975 DOI: 10.1007/978-1-4939-9139-6_11 |
0.662 |
|
2019 |
Pflepsen KR, Peterson CD, Kitto KF, Vulchanova L, Wilcox GL, Fairbanks CA. Detailed Method for Intrathecal Delivery of Gene Therapeutics by Direct Lumbar Puncture in Mice. Methods in Molecular Biology (Clifton, N.J.). 1937: 305-312. PMID 30706406 DOI: 10.1007/978-1-4939-9065-8_20 |
0.598 |
|
2019 |
Bruce D, Peterson C, Fairbanks C, Wilcox G. (260) Examining Sex Differences in Analgesic Tolerance to a Peripherally-Restricted Opioid combination The Journal of Pain. 20: S39. DOI: 10.1016/J.Jpain.2019.01.182 |
0.708 |
|
2019 |
Peterson C, Wataaja J, Kitto K, Verma H, Delpire E, Wilcox G, Fairbanks C. (219) Selective Antagonism of Spinal GluN2B EPSCs by Agmatine The Journal of Pain. 20: S30. DOI: 10.1016/J.Jpain.2019.01.140 |
0.703 |
|
2018 |
Waataja JJ, Peterson CD, Verma H, Goracke-Postle CJ, Séguéla P, Delpire E, Wilcox GL, Fairbanks CA. Agmatine Preferentially Antagonizes GluN2B-Containing N-Methyl-D-Aspartate Receptors in Spinal Cord. Journal of Neurophysiology. PMID 30427758 DOI: 10.1152/Jn.00172.2018 |
0.818 |
|
2018 |
Larson C, Peterson C, Bruce D, Kitto K, Fairbanks C, Wilcox G. Peripherally restricted opioid combination therapy reduces pain behavior in mouse and pig The Journal of Pain. 19: S79. DOI: 10.1016/J.Jpain.2017.12.188 |
0.682 |
|
2018 |
Peterson C, Wataaja J, Kitto K, Verma H, Delpire E, Wilcox G, Fairbanks C. Agmatine reduction of neuropathic pain requires spinal NMDA receptors containing GluN2B subunits The Journal of Pain. 19: S79. DOI: 10.1016/J.Jpain.2017.12.186 |
0.694 |
|
2017 |
Peterson CD, Kitto KF, Akgün E, Lunzer MM, Riedl MS, Vulchanova L, Wilcox GL, Portoghese PS, Fairbanks CA. A bivalent ligand that activates mu opioid receptor and antagonizes mGluR5 receptor reduces neuropathic pain in mice. Pain. PMID 28891868 DOI: 10.1097/J.Pain.0000000000001050 |
0.716 |
|
2017 |
Lim TKY, Anderson KM, Hari P, Di Falco M, Reihsen TE, Wilcox GL, Belani KG, LaBoissiere S, Pinto MR, Beebe DS, Kehl L, Stone LS. Evidence for a role of nerve injury in painful intervertebral disc degeneration: A cross-sectional proteomic analysis of human cerebrospinal fluid. The Journal of Pain : Official Journal of the American Pain Society. PMID 28652204 DOI: 10.1016/J.Jpain.2017.06.002 |
0.381 |
|
2017 |
Barney CC, Merbler AM, Quest K, Byiers BJ, Wilcox GL, Schwantes S, Roiko SA, Feyma T, Beisang A, Symons FJ. A case-controlled comparison of postoperative analgesic dosing between girls with Rett syndrome and girls with and without developmental disability undergoing spinal fusion surgery. Paediatric Anaesthesia. PMID 28177174 DOI: 10.1111/Pan.13066 |
0.328 |
|
2017 |
Peterson C, Shah R, Kitto K, Goracke-Postle C, Fairbanks C, Wagner C, Wilcox G. (204) Inhibition of MOR-NMDAR interaction restores opioid efficacy and inhibits neuropathic pain The Journal of Pain. 18: S27. DOI: 10.1016/J.Jpain.2017.02.367 |
0.807 |
|
2017 |
Bruce D, Peterson C, Kitto K, Fairbanks C, Wilcox G. (199) Peripherally-restricted opioid combination therapy synergizes in multiple pain states The Journal of Pain. 18: S25-S26. DOI: 10.1016/J.Jpain.2017.02.106 |
0.674 |
|
2015 |
Chabot-Doré AJ, Millecamps M, Naso L, Devost D, Trieu P, Piltonen M, Diatchenko L, Fairbanks CA, Wilcox GL, Hébert TE, Stone LS. Dual allosteric modulation of opioid antinociceptive potency by α2A-adrenoceptors. Neuropharmacology. 99: 285-300. PMID 26254859 DOI: 10.1016/J.Neuropharm.2015.08.010 |
0.718 |
|
2015 |
Wilcox CE, Mayer AR, Teshiba TM, Ling J, Smith BW, Wilcox GL, Mullins PG. The Subjective Experience of Pain: An FMRI Study of Percept-Related Models and Functional Connectivity. Pain Medicine (Malden, Mass.). PMID 25989475 DOI: 10.1111/Pme.12785 |
0.316 |
|
2015 |
Symons FJ, ElGhazi I, Reilly BG, Barney CC, Hanson L, Panoskaltsis-Mortari A, Armitage IM, Wilcox GL. Can biomarkers differentiate pain and no pain subgroups of nonverbal children with cerebral palsy? A preliminary investigation based on noninvasive saliva sampling. Pain Medicine (Malden, Mass.). 16: 249-56. PMID 25234580 DOI: 10.1111/Pme.12545 |
0.302 |
|
2015 |
Schuster DJ, Metcalf MD, Kitto KF, Messing RO, Fairbanks CA, Wilcox GL. Ligand requirements for involvement of PKCε in synergistic analgesic interactions between spinal μ and δ opioid receptors. British Journal of Pharmacology. 172: 642-53. PMID 24827408 DOI: 10.1111/Bph.12774 |
0.794 |
|
2015 |
Chabot-Doré AJ, Schuster DJ, Stone LS, Wilcox GL. Analgesic synergy between opioid and α2 -adrenoceptors. British Journal of Pharmacology. 172: 388-402. PMID 24641506 DOI: 10.1111/Bph.12695 |
0.694 |
|
2015 |
Chabot-Doré AJ, Millecamps M, Naso L, Devost D, Trieu P, Piltonen M, Diatchenko L, Fairbanks CA, Wilcox GL, Hébert TE, Stone LS. Dual allosteric modulation of opioid antinociceptive potency by α2A-adrenoceptors Neuropharmacology. 99: 285-300. DOI: 10.1016/j.neuropharm.2015.08.010 |
0.64 |
|
2014 |
Stone LS, German JP, Kitto KF, Fairbanks CA, Wilcox GL. Morphine and clonidine combination therapy improves therapeutic window in mice: synergy in antinociceptive but not in sedative or cardiovascular effects. Plos One. 9: e109903. PMID 25299457 DOI: 10.1371/Journal.Pone.0109903 |
0.712 |
|
2014 |
Peterson C, Braun P, Schuster D, Schnell S, Kitto K, Churchill C, Wilcox G, Vulchanova L, Fairbanks C. (273) Expression of human arginine decarboxylase (hADC) in the spinal cord and dorsal root ganglia following intrathecal delivery of an AAV9-hADC vector reduces established chronic pain responses in rodents The Journal of Pain. 15: S44. DOI: 10.1016/J.Jpain.2014.01.182 |
0.776 |
|
2013 |
Wade CL, Krumenacher P, Kitto KF, Peterson CD, Wilcox GL, Fairbanks CA. Effect of chronic pain on fentanyl self-administration in mice. Plos One. 8: e79239. PMID 24260176 DOI: 10.1371/Journal.Pone.0079239 |
0.801 |
|
2013 |
Schuster DJ, Kitto KF, Overland AC, Messing RO, Stone LS, Fairbanks CA, Wilcox GL. Protein kinase Cε is required for spinal analgesic synergy between delta opioid and alpha-2A adrenergic receptor agonist pairs. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 13538-46. PMID 23946412 DOI: 10.1523/Jneurosci.4013-12.2013 |
0.825 |
|
2013 |
Piletz JE, Aricioglu F, Cheng JT, Fairbanks CA, Gilad VH, Haenisch B, Halaris A, Hong S, Lee JE, Li J, Liu P, Molderings GJ, Rodrigues AL, Satriano J, Seong GJ, ... Wilcox G, et al. Agmatine: clinical applications after 100 years in translation. Drug Discovery Today. 18: 880-93. PMID 23769988 DOI: 10.1016/J.Drudis.2013.05.017 |
0.594 |
|
2012 |
Metcalf MD, Yekkirala AS, Powers MD, Kitto KF, Fairbanks CA, Wilcox GL, Portoghese PS. The δ opioid receptor agonist SNC80 selectively activates heteromeric μ-δ opioid receptors. Acs Chemical Neuroscience. 3: 505-9. PMID 22860219 DOI: 10.1021/Cn3000394 |
0.684 |
|
2012 |
Schuster D, Schnell S, Kitto K, Overland A, Stone L, Messing R, Fairbanks C, Wilcox G. Immunohistochemical evaluation of the localization of protein kinase C-epsilon in dorsal root ganglia and spinal cord. The Journal of Pain. 13: S42. DOI: 10.1016/J.Jpain.2012.01.179 |
0.783 |
|
2010 |
Schmidt BL, Hamamoto DT, Simone DA, Wilcox GL. Mechanism of cancer pain. Molecular Interventions. 10: 164-78. PMID 20539035 DOI: 10.1124/Mi.10.3.7 |
0.4 |
|
2010 |
Vulchanova L, Schuster DJ, Belur LR, Riedl MS, Podetz-Pedersen KM, Kitto KF, Wilcox GL, McIvor RS, Fairbanks CA. Differential adeno-associated virus mediated gene transfer to sensory neurons following intrathecal delivery by direct lumbar puncture. Molecular Pain. 6: 31. PMID 20509925 DOI: 10.1186/1744-8069-6-31 |
0.752 |
|
2010 |
Overland AC, Kitto KF, Fairbanks CA, Stone LS, Wilcox GL. Specific involvement of PKC-ε in the synergistic interaction between agonists acting at alpha-2-adrenergic and delta-opioid receptors in spinal cord F1000research. 1. DOI: 10.7490/F1000Research.85.1 |
0.827 |
|
2009 |
Overland AC, Kitto KF, Chabot-Doré AJ, Rothwell PE, Fairbanks CA, Stone LS, Wilcox GL. Protein kinase C mediates the synergistic interaction between agonists acting at alpha2-adrenergic and delta-opioid receptors in spinal cord. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 13264-73. PMID 19846714 DOI: 10.1523/Jneurosci.1907-09.2009 |
0.829 |
|
2009 |
Wade CL, Eskridge LL, Nguyen HO, Kitto KF, Stone LS, Wilcox G, Fairbanks CA. Immunoneutralization of agmatine sensitizes mice to micro-opioid receptor tolerance. The Journal of Pharmacology and Experimental Therapeutics. 331: 539-46. PMID 19684255 DOI: 10.1124/Jpet.109.155424 |
0.818 |
|
2009 |
Fairbanks CA, Stone LS, Wilcox GL. Pharmacological profiles of alpha 2 adrenergic receptor agonists identified using genetically altered mice and isobolographic analysis. Pharmacology & Therapeutics. 123: 224-38. PMID 19393691 DOI: 10.1016/J.Pharmthera.2009.04.001 |
0.712 |
|
2009 |
Fairbanks CA, Kitto KF, Nguyen HO, Stone LS, Wilcox GL. Clonidine and dexmedetomidine produce antinociceptive synergy in mouse spinal cord. Anesthesiology. 110: 638-47. PMID 19212267 DOI: 10.1097/Aln.0B013E318195B51D |
0.7 |
|
2009 |
Riedl MS, Schnell SA, Overland AC, Chabot-Doré AJ, Taylor AM, Ribeiro-da-Silva A, Elde RP, Wilcox GL, Stone LS. Coexpression of alpha 2A-adrenergic and delta-opioid receptors in substance P-containing terminals in rat dorsal horn. The Journal of Comparative Neurology. 513: 385-98. PMID 19180644 DOI: 10.1002/Cne.21982 |
0.819 |
|
2009 |
Stein C, Clark JD, Oh U, Vasko MR, Wilcox GL, Overland AC, Vanderah TW, Spencer RH. Peripheral mechanisms of pain and analgesia. Brain Research Reviews. 60: 90-113. PMID 19150465 DOI: 10.1016/J.Brainresrev.2008.12.017 |
0.808 |
|
2009 |
Wade C, Kitto K, Schuster D, Fairbanks C, Wilcox G. Chronic pain and opioid self-administration The Journal of Pain. 10: S23. DOI: 10.1016/J.Jpain.2009.01.098 |
0.803 |
|
2009 |
Riedl MS, Schnell SA, Overland AC, Chabot-Doré AJ, Taylor AM, Ribeiro-Da-Silva A, Elde RP, Wilcox GL, Stone LS. Erratum: Coexpression of α2A-adrenergic and δ-opioid receptors in substance P-containing terminals in rat dorsal horn (Journal of Comparative Neurology (2009) vol. 513 (385-398)) The Journal of Comparative Neurology. 514. DOI: 10.1002/Cne.22068 |
0.802 |
|
2008 |
Schreiber KL, Beitz AJ, Wilcox GL. Activation of spinal microglia in a murine model of peripheral inflammation-induced, long-lasting contralateral allodynia. Neuroscience Letters. 440: 63-7. PMID 18541374 DOI: 10.1016/J.Neulet.2008.05.044 |
0.686 |
|
2007 |
Stone LS, Kitto KF, Eisenach JC, Fairbanks CA, Wilcox GL. ST91 [2-(2,6-diethylphenylamino)-2-imidazoline hydrochloride]-mediated spinal antinociception and synergy with opioids persists in the absence of functional alpha-2A- or alpha-2C-adrenergic receptors. The Journal of Pharmacology and Experimental Therapeutics. 323: 899-906. PMID 17855473 DOI: 10.1124/Jpet.107.125526 |
0.664 |
|
2007 |
Overland A, Goracke-Postle C, Stone L, Fairbanks C, Wilcox G. (605) The Journal of Pain. 8: S2. DOI: 10.1016/J.Jpain.2007.02.007 |
0.743 |
|
2006 |
Vit JP, Ohara PT, Tien DA, Fike JR, Eikmeier L, Beitz A, Wilcox GL, Jasmin L. The analgesic effect of low dose focal irradiation in a mouse model of bone cancer is associated with spinal changes in neuro-mediators of nociception. Pain. 120: 188-201. PMID 16360279 DOI: 10.1016/J.Pain.2005.10.033 |
0.409 |
|
2005 |
Wacnik PW, Baker CM, Herron MJ, Kren BT, Blazar BR, Wilcox GL, Hordinsky MK, Beitz AJ, Ericson ME. Tumor-induced mechanical hyperalgesia involves CGRP receptors and altered innervation and vascularization of DsRed2 fluorescent hindpaw tumors. Pain. 115: 95-106. PMID 15836973 DOI: 10.1016/J.Pain.2005.02.024 |
0.703 |
|
2005 |
Wacnik PW, Eikmeier LJ, Simone DA, Wilcox GL, Beitz AJ. Nociceptive characteristics of tumor necrosis factor-alpha in naive and tumor-bearing mice. Neuroscience. 132: 479-91. PMID 15802198 DOI: 10.1016/J.Neuroscience.2004.12.035 |
0.689 |
|
2004 |
Stone LS, Wilcox GL. Alpha-2-adrenergic and opioid receptor additivity in rat locus coeruleus neurons. Neuroscience Letters. 361: 265-8. PMID 15135944 DOI: 10.1016/J.Neulet.2003.12.065 |
0.379 |
|
2004 |
Stone LS, Vulchanova L, Riedl MS, Williams FG, Wilcox GL, Elde R. Effects of peripheral nerve injury on delta opioid receptor (DOR) immunoreactivity in the rat spinal cord. Neuroscience Letters. 361: 208-11. PMID 15135930 DOI: 10.1016/J.Neulet.2003.12.067 |
0.489 |
|
2004 |
Zhao C, Wacnik PW, Tall JM, Johns DC, Wilcox GL, Meyer RA, Raja SN. Analgesic effects of a soy-containing diet in three murine bone cancer pain models. The Journal of Pain : Official Journal of the American Pain Society. 5: 104-10. PMID 15042518 DOI: 10.1016/J.Jpain.2003.12.001 |
0.717 |
|
2003 |
Stone LS, Fairbanks CA, Wilcox GL. Moxonidine, a mixed alpha(2)-adrenergic and imidazoline receptor agonist, identifies a novel adrenergic target for spinal analgesia. Annals of the New York Academy of Sciences. 1009: 378-85. PMID 15028616 DOI: 10.1196/Annals.1304.051 |
0.686 |
|
2003 |
Yu CG, Fairbanks CA, Wilcox GL, Yezierski RP. Effects of agmatine, interleukin-10, and cyclosporin on spontaneous pain behavior after excitotoxic spinal cord injury in rats. The Journal of Pain : Official Journal of the American Pain Society. 4: 129-40. PMID 14622710 DOI: 10.1054/Jpai.2003.11 |
0.661 |
|
2003 |
Kehl LJ, Hamamoto DT, Wacnik PW, Croft DL, Norsted BD, Wilcox GL, Simone DA. A cannabinoid agonist differentially attenuates deep tissue hyperalgesia in animal models of cancer and inflammatory muscle pain. Pain. 103: 175-86. PMID 12749972 DOI: 10.1016/S0304-3959(02)00450-5 |
0.735 |
|
2003 |
Wacnik PW, Kehl LJ, Trempe TM, Ramnaraine ML, Beitz AJ, Wilcox GL. Tumor implantation in mouse humerus evokes movement-related hyperalgesia exceeding that evoked by intramuscular carrageenan. Pain. 101: 175-86. PMID 12507712 DOI: 10.1016/S0304-3959(02)00312-3 |
0.731 |
|
2002 |
Laughlin TM, Tram KV, Wilcox GL, Birnbaum AK. Comparison of antiepileptic drugs tiagabine, lamotrigine, and gabapentin in mouse models of acute, prolonged, and chronic nociception. The Journal of Pharmacology and Experimental Therapeutics. 302: 1168-75. PMID 12183677 DOI: 10.1124/Jpet.302.3.1168 |
0.369 |
|
2002 |
Fairbanks CA, Stone LS, Kitto KF, Nguyen HO, Posthumus IJ, Wilcox GL. alpha(2C)-Adrenergic receptors mediate spinal analgesia and adrenergic-opioid synergy. The Journal of Pharmacology and Experimental Therapeutics. 300: 282-90. PMID 11752127 DOI: 10.1124/Jpet.300.1.282 |
0.65 |
|
2001 |
Cain DM, Wacnik PW, Eikmeier L, Beitz A, Wilcox GL, Simone DA. Functional interactions between tumor and peripheral nerve in a model of cancer pain in the mouse. Pain Medicine (Malden, Mass.). 2: 15-23. PMID 15102313 DOI: 10.1046/J.1526-4637.2001.002001015.X |
0.732 |
|
2001 |
Cain DM, Wacnik PW, Turner M, Wendelschafer-Crabb G, Kennedy WR, Wilcox GL, Simone DA. Functional interactions between tumor and peripheral nerve: changes in excitability and morphology of primary afferent fibers in a murine model of cancer pain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 9367-76. PMID 11717370 DOI: 10.1046/J.1529-8027.2002.02011_5.X |
0.685 |
|
2001 |
Wacnik PW, Eikmeier LJ, Ruggles TR, Ramnaraine ML, Walcheck BK, Beitz AJ, Wilcox GL. Functional interactions between tumor and peripheral nerve: morphology, algogen identification, and behavioral characterization of a new murine model of cancer pain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 9355-66. PMID 11717369 DOI: 10.1523/Jneurosci.21-23-09355.2001 |
0.7 |
|
2001 |
Laughlin TM, Larson AA, Wilcox GL. Mechanisms of induction of persistent nociception by dynorphin. The Journal of Pharmacology and Experimental Therapeutics. 299: 6-11. PMID 11561057 |
0.389 |
|
2000 |
Yu CG, Marcillo AE, Fairbanks CA, Wilcox GL, Yezierski RP. Agmatine improves locomotor function and reduces tissue damage following spinal cord injury. Neuroreport. 11: 3203-7. PMID 11043549 DOI: 10.1097/00001756-200009280-00031 |
0.669 |
|
2000 |
Fairbanks CA, Schreiber KL, Brewer KL, Yu CG, Stone LS, Kitto KF, Nguyen HO, Grocholski BM, Shoeman DW, Kehl LJ, Regunathan S, Reis DJ, Yezierski RP, Wilcox GL. Agmatine reverses pain induced by inflammation, neuropathy, and spinal cord injury. Proceedings of the National Academy of Sciences of the United States of America. 97: 10584-9. PMID 10984543 DOI: 10.1073/Pnas.97.19.10584 |
0.781 |
|
2000 |
Fairbanks CA, Nguyen HO, Grocholski BM, Wilcox GL. Moxonidine, a selective imidazoline-alpha2 -adrenergic receptor agonist, produces spinal synergistic antihyperalgesia with morphine in nerve-injured mice. Anesthesiology. 93: 765-73. PMID 10969310 DOI: 10.1097/00000542-200009000-00026 |
0.726 |
|
2000 |
Fairbanks CA, Wilcox GL. Spinal plasticity of acute opioid tolerance. Journal of Biomedical Science. 7: 200-12. PMID 10810238 DOI: 10.1007/Bf02255467 |
0.728 |
|
2000 |
Laughlin TM, Bethea JR, Yezierski RP, Wilcox GL. Cytokine involvement in dynorphin-induced allodynia. Pain. 84: 159-67. PMID 10666520 DOI: 10.1016/S0304-3959(99)00195-5 |
0.34 |
|
2000 |
Fairbanks CA, Posthumus IJ, Kitto KF, Stone LS, Wilcox GL. Moxonidine, a selective imidazoline/alpha(2) adrenergic receptor agonist, synergizes with morphine and deltorphin II to inhibit substance P-induced behavior in mice. Pain. 84: 13-20. PMID 10601668 DOI: 10.1016/S0304-3959(99)00171-2 |
0.71 |
|
1999 |
Stone LS, Vulchanova L, Riedl MS, Wang J, Williams FG, Wilcox GL, Elde R. Effects of peripheral nerve injury on alpha-2A and alpha-2C adrenergic receptor immunoreactivity in the rat spinal cord. Neuroscience. 93: 1399-407. PMID 10501465 DOI: 10.1016/S0306-4522(99)00209-2 |
0.441 |
|
1999 |
Fairbanks CA, Wilcox GL. Moxonidine, a selective α2-adrenergic and imidazoline receptor agonist, produces spinal antinociception in mice Journal of Pharmacology and Experimental Therapeutics. 290: 403-412. PMID 10381806 |
0.608 |
|
1999 |
Laughlin TM, Kitto KF, Wilcox GL. Redox manipulation of NMDA receptors in vivo: Alteration of acute pain transmission and dynorphin-induced allodynia Pain. 80: 37-43. PMID 10204716 DOI: 10.1016/S0304-3959(98)00191-2 |
0.401 |
|
1999 |
Fairbanks CA, Wilcox GL. Spinal antinociceptive synergism between morphine and clonidine persists in mice made acutely or chronically tolerant to morphine Journal of Pharmacology and Experimental Therapeutics. 288: 1107-1116. PMID 10027848 |
0.659 |
|
1998 |
Stone LS, Broberger C, Vulchanova L, Wilcox GL, Hökfelt T, Riedl MS, Elde R. Differential Distribution of α2Aand α2CAdrenergic Receptor Immunoreactivity in the Rat Spinal Cord The Journal of Neuroscience. 18: 5928-5937. DOI: 10.1523/Jneurosci.18-15-05928.1998 |
0.443 |
|
1997 |
Stone LS, Fairbanks CA, Laughlin TM, Nguyen HO, Bushy TM, Wessendorf MW, Wilcox GL. Spinal analgesic actions of the new endogenous opioid peptides endomorphin-1 and -2. Neuroreport. 8: 3131-5. PMID 9331928 DOI: 10.1097/00001756-199709290-00025 |
0.732 |
|
1997 |
Fairbanks CA, Wilcox GL. Acute tolerance to spinally administered morphine compares mechanistically with chronically induced morphine tolerance Journal of Pharmacology and Experimental Therapeutics. 282: 1408-1417. PMID 9316854 |
0.669 |
|
1997 |
Stone LS, MacMillan LB, Kitto KF, Limbird LE, Wilcox GL. The alpha2a adrenergic receptor subtype mediates spinal analgesia evoked by alpha2 agonists and is necessary for spinal adrenergic-opioid synergy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 7157-65. PMID 9278550 |
0.452 |
|
1997 |
Laughlin TM, Vanderah TW, Lashbrook J, Nichols ML, Ossipov M, Porreca F, Wilcox GL. Spinally administered dynorphin A produces long-lasting allodynia: involvement of NMDA but not opioid receptors. Pain. 72: 253-60. PMID 9272810 DOI: 10.1016/S0304-3959(97)00046-8 |
0.552 |
|
1997 |
Kehl LJ, Fairbanks CA, Laughlin TM, Wilcox GL. Neurogenesis in postnatal rat spinal cord: A study in primary culture Science. 276: 586-589. PMID 9110976 DOI: 10.1126/Science.276.5312.586 |
0.656 |
|
1997 |
Wotta DR, Birnbaum AK, Wilcox GL, Eide R, Law PY. μ-Opioid receptor regulates CFTR coexpressed in Xenopus oocytes in a cAMP independent manner Molecular Brain Research. 44: 55-65. PMID 9030698 DOI: 10.1016/S0169-328X(96)00189-1 |
0.413 |
|
1997 |
Stone LS, MacMillan LB, Kitto KF, Limbird LE, Wilcox GL. The α2aAdrenergic Receptor Subtype Mediates Spinal Analgesia Evoked by α2Agonists and Is Necessary for Spinal Adrenergic–Opioid Synergy The Journal of Neuroscience. 17: 7157-7165. DOI: 10.1523/Jneurosci.17-18-07157.1997 |
0.539 |
|
1996 |
Vanderah TW, Laughlin T, Lashbrook JM, Nichols ML, Wilcox GL, Ossipov MH, Malan TP, Porreca F. Single intrathecal injections of dynorphin A or des-Tyr-dynorphins produce long-lasting allodynia in rats: blockade by MK-801 but not naloxone. Pain. 68: 275-81. PMID 9121815 DOI: 10.1016/S0304-3959(96)03225-3 |
0.509 |
|
1996 |
Roche AK, Cook M, Wilcox GL, Kajander KC. A nitric oxide synthesis inhibitor (L-NAME) reduces licking behavior and Fos-labeling in the spinal cord of rats during formalin-induced inflammation Pain. 66: 331-341. PMID 8880857 DOI: 10.1016/0304-3959(96)03025-4 |
0.352 |
|
1996 |
Lai J, Riedl M, Stone LS, Arvidsson U, Bilsky EJ, Wilcox GL, Elde R, Porreca F. Immunofluorescence analysis of antisense oligodeoxynucleotide-mediated 'knock-down' of the mouse delta opioid receptor in vitro and in vivo. Neuroscience Letters. 213: 205-8. PMID 8873150 DOI: 10.1016/0304-3940(96)12883-4 |
0.52 |
|
1995 |
Birnbaum AK, Wotta DR, Law PY, Wilcox GL. Functional expression of adrenergic and opioid receptors in Xenopus oocytes: interaction between α2- and β2-adrenergic receptors Molecular Brain Research. 28: 72-80. PMID 7707880 DOI: 10.1016/0169-328X(94)00185-H |
0.365 |
|
1995 |
Bétoin F, Advenier C, Fardin V, Wilcox GL, Lavarenne J, Eschalier A. In vitro and in vivo evidence for a tachykinin NK1 receptor antagonist effect of vapreotide, an analgesic cyclic analog of somatostatin European Journal of Pharmacology. 279: 241-249. PMID 7556407 DOI: 10.1016/0014-2999(95)00168-K |
0.326 |
|
1995 |
Budai D, Wilcox GL, Larson AA. Effects of nitric oxide availability on responses of spinal wide dynamic range neurons to excitatory amino acids. European Journal of Pharmacology. 278: 39-47. PMID 7545123 DOI: 10.1016/0014-2999(95)00100-Y |
0.311 |
|
1994 |
Wu HH, Wilcox GL, McLoon SC. Implantation of AtT-20 or genetically modified AtT-20/hENK cells in mouse spinal cord induced antinociception and opioid tolerance. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 14: 4806-14. PMID 8046451 DOI: 10.1523/Jneurosci.14-08-04806.1994 |
0.418 |
|
1994 |
Mestre C, Pélissier T, Fialip J, Wilcox GL, Eschalier A. A method to perform direct transcutaneous intrathecal injection in rats Journal of Pharmacological and Toxicological Methods. 32: 197-200. PMID 7881133 DOI: 10.1016/1056-8719(94)90087-6 |
0.385 |
|
1994 |
Wu HH, Lester BR, Sun Z, Wilcox GL. Antinociception following implantation of mouse B16 melanoma cells in mouse and rat spinal cord. Pain. 56: 203-10. PMID 7516533 DOI: 10.1016/0304-3959(94)90095-7 |
0.396 |
|
1993 |
Wu HH, McLoon SC, Wilcox GL. Antinociception following implantation of AtT-20 and genetically modified AtT-20/hENK cells in rat spinal cord. Journal of Neural Transplantation & Plasticity. 4: 15-26. PMID 8110861 DOI: 10.1155/Np.1993.15 |
0.432 |
|
1993 |
Wilcox GL. Spinal mediators of nociceptive neurotransmission and hyperalgesia. Relationships among synaptic plasticity, analgesic tolerance, and blood flow Aps Journal. 2: 265-275. DOI: 10.1016/S1058-9139(05)80257-8 |
0.458 |
|
1992 |
Budai D, Wilcox GL, Larson AA. Enhancement of NMDA-evoked neuronal activity by glycine in the rat spinal cord in vivo. Neuroscience Letters. 135: 265-8. PMID 1625808 DOI: 10.1016/0304-3940(92)90452-D |
0.362 |
|
1992 |
Lee JH, Wilcox GL, Beitz AJ. Nitric oxide mediates fos expression in the spinal cord induced by mechanical noxious stimulation Neuroreport. 3: 841-844. PMID 1421085 DOI: 10.1097/00001756-199210000-00005 |
0.402 |
|
1992 |
Budai D, Wilcox GL, Larson AA. Modulation of N-methyl-D-aspartate and (R,S)-alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate (AMPA) responses of spinal nociceptive neurons by a N-terminal fragment of substance P. European Journal of Pharmacology. 216: 441-4. PMID 1385165 DOI: 10.1016/0014-2999(92)90443-8 |
0.354 |
|
1992 |
Roerig SC, Lei S, Kitto K, Hylden JKL, Wilcox GL. Spinal interactions between opioid and noradrenergic agonists in mice: Multiplicativity involves delta and alpha-2 receptors Journal of Pharmacology and Experimental Therapeutics. 262: 365-374. PMID 1378095 |
0.376 |
|
1992 |
Kitto KF, Haley JE, Wilcox GL. Involvement of nitric oxide in spinally mediated hyperalgesia in the mouse Neuroscience Letters. 148: 1-5. PMID 1284437 DOI: 10.1016/0304-3940(92)90790-E |
0.327 |
|
1991 |
Alhaider AA, Lei SZ, Wilcox GL. Spinal 5-HT3 receptor-mediated antinociception: Possible release of GABA Journal of Neuroscience. 11: 1881-1888. PMID 2066767 DOI: 10.1523/Jneurosci.11-07-01881.1991 |
0.347 |
|
1991 |
Lei SZ, Lipkowski AW, Wilcox GL. Opioid and neurokinin activities of substance P fragments and their analogs European Journal of Pharmacology. 193: 209-215. PMID 1710992 DOI: 10.1016/0014-2999(91)90038-R |
0.321 |
|
1991 |
Roerig SC, Hoffman RG, Takemori AE, Wilcox GL, Fujimoto JM. Isobolographic analysis of analgesic interactions between intrathecally and intracerebroventricularly administered fentanyl, morphine and D-Ala2-D-Leu5-enkephalin in morphine-tolerant and nontolerant mice. The Journal of Pharmacology and Experimental Therapeutics. 257: 1091-9. PMID 1646321 |
0.331 |
|
1990 |
Aanonsen LM, Lei S, Wilcox GL. Excitatory amino acid receptors and nociceptive neurotransmission in rat spinal cord Pain. 41: 309-321. PMID 1975091 DOI: 10.1016/0304-3959(90)90008-2 |
0.397 |
|
1990 |
Wilcox G. Transmission and modulation of pain at the spinal level Pain. 41: S248. DOI: 10.1016/0304-3959(90)92622-W |
0.426 |
|
1990 |
Wilcox GL. Transmission and modulation of pain at the spinal level Pain. 41: S247. DOI: 10.1016/0304-3959(90)92622-W |
0.313 |
|
1990 |
Lei S, Wilcox GL. Excitatory amino acid and opioid receptor regulation of spinal nociceptive neurotransmission European Journal of Pharmacology. 183: 1438-1439. DOI: 10.1016/0014-2999(90)94575-I |
0.471 |
|
1990 |
Alhaider AA, Lei S, Kitto KF, Wilcox GL. Behavioral and electrophysiologial studies of 5-HT3 receptor-mediated spinal antinociception European Journal of Pharmacology. 183: 1671. DOI: 10.1016/0014-2999(90)91964-D |
0.373 |
|
1990 |
Wilcox GL, Alhaider AA. Nociceptive and antinociceptive action of serotonergic agonists administered intrathecally Serotonin and Pain: Proceedings of the International Symposium On Serotonin and Pain. Ics879. 205-219. |
0.306 |
|
1989 |
Gaumann DM, Yaksh TL, Post C, Wilcox GL, Rodriguez M. Intrathecal somatostatin in cat and mouse studies on pain, motor behavior, and histopathology. Anesthesia & Analgesia. 68: 623-632. DOI: 10.1213/00000539-198905000-00015 |
0.371 |
|
1988 |
Wilcox GL. Pharmacological studies of grooming and scratching behavior elicited by spinal substance P and excitatory amino acids Annals of the New York Academy of Sciences. 525: 228-236. PMID 2455461 DOI: 10.1111/J.1749-6632.1988.Tb38608.X |
0.415 |
|
1987 |
Wilcox GL, Carlsson KH, Jochim A, Jurna I. Mutual potentiation of antinociceptive effects of morphine and clonidine on motor and sensory responses in rat spinal cord Brain Research. 405: 84-93. PMID 3567599 DOI: 10.1016/0006-8993(87)90992-9 |
0.401 |
|
1987 |
Hwang AS, Wilcox GL. Analgesic properties of intrathecally administered heterocyclic antidepressants Pain. 28: 343-355. PMID 3494977 DOI: 10.1016/0304-3959(87)90068-6 |
0.46 |
|
1987 |
Aanonsen LM, Wilcox GL. Nociceptive action of excitatory amino acids in the mouse: Effects of spinally administered opioids, phencyclidine and sigma agonists Journal of Pharmacology and Experimental Therapeutics. 243: 9-19. PMID 2822907 |
0.394 |
|
1986 |
Hylden JLK, Wilcox GL. Antinociceptive effect of morphine on rat spinothalamic tract and other dorsal horn neurons Neuroscience. 19: 393-401. PMID 3774148 DOI: 10.1016/0306-4522(86)90269-1 |
0.487 |
|
1986 |
Aanonsen LM, Wilcox GL. Phencyclidine selectively blocks a spinal action of N-methyl-d-aspartate in mice Neuroscience Letters. 67: 191-197. PMID 2425302 DOI: 10.1016/0304-3940(86)90396-4 |
0.331 |
|
1986 |
Sutaeg Hwang A, Wilcox GL. Intradermal hypertonic saline-induced behavior as a nociceptive test in mice Life Sciences. 38: 2389-2396. PMID 2425207 DOI: 10.1016/0024-3205(86)90607-7 |
0.38 |
|
1984 |
Roerig SC, O'Brien SM, Fujimoto JM, Wilcox GL. Tolerance to morphine analgesia: decreased multiplicative interaction between spinal and supraspinal sites Brain Research. 308: 360-363. PMID 6548169 DOI: 10.1016/0006-8993(84)91078-3 |
0.421 |
|
1983 |
Hylden JLK, Wilcox GL. Antinociceptive action of intrathecal neurotensin in mice Peptides. 4: 517-520. PMID 6196760 DOI: 10.1016/0196-9781(83)90057-8 |
0.448 |
|
1983 |
Hylden JLK, Wilcox GL. Intrathecal serotonin in mice: Analgesia and inhibition of a spinal action of substance P Life Sciences. 33: 789-795. PMID 6193388 DOI: 10.1016/0024-3205(83)90785-3 |
0.384 |
|
1983 |
Hylden JLK, Wilcox GL. Pharmacological characterization of substance P-induced nociception in mice: Modulation by opioid and noradrenergic agonists at the spinal level Journal of Pharmacology and Experimental Therapeutics. 226: 398-404. PMID 6192235 |
0.404 |
|
1982 |
Wilcox GL. Correlates of nociception and antinociception in dorsal root potentials in the rat Neuropharmacology. 21: 745-750. PMID 7121746 DOI: 10.1016/0028-3908(82)90059-4 |
0.43 |
|
1982 |
Levine AS, Wilcox GL, Grace M, Morley JE. Tail pinch induced consummatory behaviors are associated with analgesia Physiology and Behavior. 28: 959-962. PMID 7111459 DOI: 10.1016/0031-9384(82)90160-3 |
0.326 |
|
1982 |
Hylden JLK, Wilcox GL. Intrathecal opioids block a spinal action of substance P in mice: Functional importance of both μ- and δ-receptors European Journal of Pharmacology. 86: 95-98. PMID 6186500 DOI: 10.1016/0014-2999(82)90403-4 |
0.473 |
|
1981 |
Hylden JLK, Wilcox GL. Intrathecal substance P elicits a caudally-directed biting and scratching behavior in mice Brain Research. 217: 212-215. PMID 6167328 DOI: 10.1016/0006-8993(81)90203-1 |
0.328 |
|
1981 |
Wilcox GL, Hylden JLK. Intrathecal primary afferent peptides as nociceptive stimuli allow study of postsynaptic spinal modulation of pain Pain. 10. DOI: 10.1016/0304-3959(81)90230-X |
0.414 |
|
1980 |
Hylden JLK, Wilcox GL. Intrathecal morphine in mice: A new technique European Journal of Pharmacology. 67: 313-316. PMID 6893963 DOI: 10.1016/0014-2999(80)90515-4 |
0.399 |
|
1980 |
Wilcox GL, Cleary CJ. Clonidine analgesia and hyperalgesia in the mouse spinal cord Pharmacologist. 22. |
0.332 |
|
1978 |
Hayes RL, Price DD, Bennett GJ, Wilcox GL, Mayer DJ. Differential effects of spinal cord lesions on narcotic and non-narcotic suppression of nociceptive reflexes: further evidence for the physiologic multiplicity of pain modulation. Brain Research. 155: 91-101. PMID 210897 DOI: 10.1016/0304-3959(79)90015-0 |
0.422 |
|
1978 |
Hayes RL, Price DD, Bennett GJ, Wilcox GL, Mayer DJ. Differential effects of spinal cord lesions on narcotic and non-narcotic supression of nociceptive reflexes: Further evidence for the physiologic multiplicity of pain modulation Brain Research. 155: 91-101. DOI: 10.1016/0006-8993(78)90307-4 |
0.308 |
|
1976 |
Wilcox GL, Dewey WL. Morphine analgesia in spinal mice and rats: cholinergic mechanisms Pharmacologist. 18. |
0.349 |
|
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