Steven A. Akman - Publications

Affiliations: 
Wake Forest University School of Medicine, Winston-Salem, NC, United States 
Area:
Molecular Biology, Biochemistry

49 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Routh ED, Creacy SD, Beerbower PE, Akman SA, Vaughn JP, Smaldino PJ. A G-quadruplex DNA-affinity Approach for Purification of Enzymatically Active G4 Resolvase1. Journal of Visualized Experiments : Jove. PMID 28362374 DOI: 10.3791/55496  0.328
2015 Swanner J, Mims J, Carroll DL, Akman SA, Furdui CM, Torti SV, Singh RN. Differential cytotoxic and radiosensitizing effects of silver nanoparticles on triple-negative breast cancer and non-triple-negative breast cells. International Journal of Nanomedicine. 10: 3937-53. PMID 26185437 DOI: 10.2147/Ijn.S80349  0.345
2015 Smaldino PJ, Routh ED, Kim JH, Giri B, Creacy SD, Hantgan RR, Akman SA, Vaughn JP. Mutational Dissection of Telomeric DNA Binding Requirements of G4 Resolvase 1 Shows that G4-Structure and Certain 3'-Tail Sequences Are Sufficient for Tight and Complete Binding. Plos One. 10: e0132668. PMID 26172836 DOI: 10.1371/Journal.Pone.0132668  0.337
2014 Cowherd S, Melin S, Akman S, Cole J, Lawrence J. Abstract CT302: A phase II clinical trial of weekly paclitaxel and carboplatin in combination with panitumumab in metastatic or recurrent breast cancer patients with triple negative disease Cancer Research. 74. DOI: 10.1158/1538-7445.Am2014-Ct302  0.301
2012 Akman SA, Adams M, Case D, Park G, Manderville RA. Mutagenicity of ochratoxin A and its hydroquinone metabolite in the SupF gene of the mutation reporter plasmid Ps189. Toxins. 4: 267-80. PMID 22606376 DOI: 10.3390/Toxins4040267  0.366
2011 Giri B, Smaldino PJ, Thys RG, Creacy SD, Routh ED, Hantgan RR, Lattmann S, Nagamine Y, Akman SA, Vaughn JP. G4 resolvase 1 tightly binds and unwinds unimolecular G4-DNA. Nucleic Acids Research. 39: 7161-78. PMID 21586581 DOI: 10.1093/Nar/Gkr234  0.364
2008 Creacy SD, Routh ED, Iwamoto F, Nagamine Y, Akman SA, Vaughn JP. G4 resolvase 1 binds both DNA and RNA tetramolecular quadruplex with high affinity and is the major source of tetramolecular quadruplex G4-DNA and G4-RNA resolving activity in HeLa cell lysates. The Journal of Biological Chemistry. 283: 34626-34. PMID 18842585 DOI: 10.1074/Jbc.M806277200  0.334
2008 Smith TR, Levine EA, Freimanis RI, Akman SA, Allen GO, Hoang KN, Liu-Mares W, Hu JJ. Polygenic model of DNA repair genetic polymorphisms in human breast cancer risk. Carcinogenesis. 29: 2132-8. PMID 18701435 DOI: 10.1093/Carcin/Bgn193  0.347
2007 Gajewski E, Gaur S, Akman SA, Matsumoto L, van Balgooy JN, Doroshow JH. Oxidative DNA base damage in MCF-10A breast epithelial cells at clinically achievable concentrations of doxorubicin. Biochemical Pharmacology. 73: 1947-56. PMID 17445777 DOI: 10.1016/J.Bcp.2007.03.022  0.412
2006 Upton DC, Wang X, Blans P, Perrino FW, Fishbein JC, Akman SA. Replication of N2-ethyldeoxyguanosine DNA adducts in the human embryonic kidney cell line 293. Chemical Research in Toxicology. 19: 960-7. PMID 16841965 DOI: 10.1021/Tx060084A  0.685
2006 Upton DC, Wang X, Blans P, Perrino FW, Fishbein JC, Akman SA. Mutagenesis by exocyclic alkylamino purine adducts in Escherichia coli. Mutation Research. 599: 1-10. PMID 16488449 DOI: 10.1016/J.Mrfmmm.2005.12.014  0.681
2005 Vaughn JP, Creacy SD, Routh ED, Joyner-Butt C, Jenkins GS, Pauli S, Nagamine Y, Akman SA. The DEXH protein product of the DHX36 gene is the major source of tetramolecular quadruplex G4-DNA resolving activity in HeLa cell lysates. The Journal of Biological Chemistry. 280: 38117-20. PMID 16150737 DOI: 10.1074/Jbc.C500348200  0.394
2005 Hart LS, Yannone SM, Naczki C, Orlando JS, Waters SB, Akman SA, Chen DJ, Ornelles D, Koumenis C. The adenovirus E4orf6 protein inhibits DNA double strand break repair and radiosensitizes human tumor cells in an E1B-55K-independent manner. The Journal of Biological Chemistry. 280: 1474-81. PMID 15507430 DOI: 10.1074/Jbc.M409934200  0.401
2003 Perrino FW, Blans P, Harvey S, Gelhaus SL, McGrath C, Akman SA, Jenkins GS, LaCourse WR, Fishbein JC. The N2-ethylguanine and the O6-ethyl- and O6-methylguanine lesions in DNA: contrasting responses from the "bypass" DNA polymerase eta and the replicative DNA polymerase alpha. Chemical Research in Toxicology. 16: 1616-23. PMID 14680376 DOI: 10.1021/Tx034164F  0.429
2003 Manderville RA, Wade Calcutt M, Dai J, Park G, Gillman IG, Noftle RE, Mohammed AK, Birincioglu M, Dizdaroglu M, Rodriguez H, Akman SA. Stoichiometric preference in copper-promoted oxidative DNA damage by ochratoxin A. Journal of Inorganic Biochemistry. 95: 87-96. PMID 12763652 DOI: 10.1016/S0162-0134(03)00104-1  0.347
2003 Manderville RA, Calcutt M, Dai J, Park G, Gillman IG, Noftle RE, Mohammed AK, Dizdaroglu M, Rodriguez H, Akman SA. Corrigendum to: “Stoichiometric preference in copper-promoted oxidative DNA damage by ochratoxin A” Journal of Inorganic Biochemistry. 97: 249. DOI: 10.1016/S0162-0134(03)00278-2  0.343
2001 Waters SB, Akman SA. A new assay to quantify in vivo repair of G:T mispairs by base excision repair Mutation Research - Dna Repair. 487: 109-119. PMID 11738937 DOI: 10.1016/S0921-8777(01)00112-4  0.317
2001 Doroshow JH, Synold TW, Somlo G, Akman SA, Gajewski E. Oxidative DNA base modifications in peripheral blood mononuclear cells of patients treated with high-dose infusional doxorubicin Blood. 97: 2839-2845. PMID 11313279 DOI: 10.1182/Blood.V97.9.2839  0.413
2000 Rodriguez H, Akman SA, Holmquist GP, Wilson GL, Driggers WJ, LeDoux SP. Mapping oxidative DNA damage using ligation-mediated polymerase chain reaction technology. Methods (San Diego, Calif.). 22: 148-56. PMID 11020329 DOI: 10.1006/Meth.2000.1055  0.382
2000 Akman SA, O'Connor TR, Rodriguez H. Mapping oxidative DNA damage and mechanisms of repair Annals of the New York Academy of Sciences. 899: 88-102. PMID 10863531 DOI: 10.1111/J.1749-6632.2000.Tb06178.X  0.403
1999 Rodriguez H, Akman SA. Measurement of oxidative DNA damage in the human p53 and PGK1 gene at nucleotide resolution Annals of the New York Academy of Sciences. 893: 382-385. PMID 10672273 DOI: 10.1111/J.1749-6632.1999.Tb07861.X  0.349
1999 Rodriguez H, Valentine MR, Holmquist GP, Akman SA, Termini J. Mapping of peroxyl radical induced damage on genomic DNA Biochemistry. 38: 16578-16588. PMID 10600120 DOI: 10.1021/Bi9918994  0.38
1998 Rodriguez H, Akman SA. Mapping oxidative DNA damage at nucleotide level Free Radical Research. 29: 499-510. PMID 10098455 DOI: 10.1080/10715769800300551  0.416
1998 Rodriguez H, Akman SA. Large scale isolation of genes as DNA fragment lengths by continuous elution electrophoresis through an agarose matrix Electrophoresis. 19: 646-652. PMID 9629891 DOI: 10.1002/Elps.1150190506  0.356
1998 Rodriguez H, Akman SA. Enhancing the sensitivity of LMPCR for mapping oxidative genomic DNA damage Free Radical Biology and Medicine. 25: S106. DOI: 10.1016/S0891-5849(98)90328-8  0.313
1998 Rodriguez H, Akman SA. Development of ligation-mediated PCR for mapping oxidative genomic DNA damage Free Radical Biology and Medicine. 25: S78. DOI: 10.1016/S0891-5849(98)90250-7  0.32
1997 Harrington C, Lan Y, Akman SA. The identification and characterization of a G4-DNA resolvase activity Journal of Biological Chemistry. 272: 24631-24636. PMID 9305932 DOI: 10.1074/Jbc.272.39.24631  0.392
1997 Rodriguez H, Drouin R, Holmquist GP, Akman SA. A hot spot for hydrogen peroxide-induced damage in the human hypoxia- inducible factor 1 binding site of the PGK 1 gene Archives of Biochemistry and Biophysics. 338: 207-212. PMID 9028873 DOI: 10.1006/Abbi.1996.9820  0.358
1997 Newman EM, Carroll M, Akman SA, Chow W, Coluzzi P, Hamasaki V, Leong LA, Margolin KA, Morgan RJ, Raschko JW, Shibata S, Somlo G, Tetef M, Yen Y, Ahn CW, et al. Pharmacokinetics and toxicity of 120-hour continuous-infusion hydroxyurea in patients with advanced solid tumors Cancer Chemotherapy and Pharmacology. 39: 254-258. PMID 8996529 DOI: 10.1007/S002800050569  0.304
1996 Akman SA, Sander F, Garbutt K. In vivo mutagenesis of the reporter plasmid pSP189 induced by exposure of host Ad293 cells to activated polymorphonuclear leukocytes. Carcinogenesis. 17: 2137-41. PMID 8895480 DOI: 10.1093/Carcin/17.10.2137  0.363
1996 Drouin R, Rodriguez H, Gao SW, Gebreyes Z, O'Connor TR, Holmquist GP, Akman SA. Cupric ion/ascorbate/hydrogen peroxide-induced DNA damage: DNA-bound copper ion primarily induces base modifications Free Radical Biology and Medicine. 21: 261-273. PMID 8855437 DOI: 10.1016/0891-5849(96)00037-8  0.384
1995 Altman SA, Zastawny TH, Randers-Eichhorn L, Cacciuttolo MA, Akman SA, Dizdaroglu M, Rao G. Formation of DNA-protein cross-links in cultured mammalian cells upon treatment with iron ions Free Radical Biology and Medicine. 19: 897-902. PMID 8582666 DOI: 10.1016/0891-5849(95)00095-F  0.303
1995 Tetef M, Margolin K, Ahn C, Akman S, Chow W, Coluzzi P, Leong L, Morgan RJ, Raschko J, Shibata S. Mitomycin C and menadione for the treatment of advanced gastrointestinal cancers: a phase II trial. Journal of Cancer Research and Clinical Oncology. 121: 103-6. PMID 7883772 DOI: 10.1007/Bf01202221  0.301
1995 Margolin KA, Akman SA, Leong LA, Morgan RJ, Somlo G, Raschko JW, Ahn C, Doroshow JH. Phase I study of mitomycin C and menadione in advanced solid tumors Cancer Chemotherapy and Pharmacology. 36: 293-298. PMID 7628048 DOI: 10.1007/Bf00689046  0.301
1995 Rodriguez H, Drouin R, Holmquist GP, O'Connor TR, Boiteux S, Laval J, Doroshow JH, Akman SA. Mapping of copper/hydrogen peroxide-induced DNA damage at nucleotide resolution in human genomic DNA by ligation-mediated polymerase chain reaction Journal of Biological Chemistry. 270: 17633-17640. PMID 7615572 DOI: 10.1074/Jbc.270.29.17633  0.407
1994 Margolin KA, Green S, Osborne K, Doroshow JH, Akman SA, Leong LA, Morgan RJ, Raschko JW, Somlo G, Hutchins L, Upchurch C. Phase II trial of 5-fluorouracil and high-dose folinic acid as first- or second-line therapy for advanced breast cancer American Journal of Clinical Oncology: Cancer Clinical Trials. 17: 175-180. PMID 8141112 DOI: 10.1097/00000421-199404000-00018  0.309
1994 Somlo G, Doroshow JH, Forman SJ, Leong LA, Margolin KA, Morgan RJ, Raschko JW, Akman SA, Ahn C, Nagasawa S, Harrison J. High-dose doxorubicin, etoposide, and cyclophosphamide with stem cell reinfusion in patients with metastatic or high-risk primary breast cancer Cancer. 73: 1678-1685. PMID 7512436 DOI: 10.1002/1097-0142(19940315)73:6<1678::Aid-Cncr2820730621>3.0.Co;2-U  0.31
1993 Akman SA, Kensler TW, Doroshow JH, Dizdaroglu M. Copper ion-mediated modification of bases in dna in vitro by benzoyl peroxide Carcinogenesis. 14: 1971-1974. PMID 8403227 DOI: 10.1093/Carcin/14.9.1971  0.359
1992 Margolin KA, Doroshow JH, Akman SA, Leong LA, Morgan RJ, Raschko JW, Somlo G, Blevins C. Effective initial therapy of advanced breast cancer with fluorouracil and high-dose, continuous infusion calcium leucovorin Journal of Clinical Oncology. 10: 1278-1283. PMID 1634917 DOI: 10.1200/Jco.1992.10.8.1278  0.305
1992 Akman SA, Doroshow JH, Kensler TW. Copper-dependent site-specific mutagenesis by benzoyl peroxide in the supf gene of the mutation reporter plasmid ps189 Carcinogenesis. 13: 1783-1787. PMID 1423838 DOI: 10.1093/Carcin/13.10.1783  0.388
1992 Akman SA, Doroshow JH, Burke TG, Dizdaroglu M. DNA base modifications induced in isolated human chromatin by NADH dehydrogenase-catalyzed reduction of doxorubicin Biochemistry. 31: 3500-3506. PMID 1313297 DOI: 10.1021/Bi00128A026  0.342
1991 Akman SA, Forrest GP, Doroshow JH, Dizdaroglu M. Mutation of potassium permanganate- and hydrogen peroxide-treated plasmid pZ189 replicating in CV-1 monkey kidney cells Mutation Research/Genetic Toxicology. 261: 123-130. PMID 1922155 DOI: 10.1016/0165-1218(91)90058-T  0.374
1991 Akman SA. Quadruplex DNA formation in a region of the tRNA gene supF associated with hydrogen peroxide mediated mutations Biochemistry. 30: 8648-8653. PMID 1888727 DOI: 10.1021/Bi00099A022  0.34
1990 Akman SA, Doroshow JH, Dizdaroglu M. Base modifications in plasmid DNA caused by potassium permanganate Archives of Biochemistry and Biophysics. 282: 202-205. PMID 2221919 DOI: 10.1016/0003-9861(90)90105-8  0.337
1990 Forrest GL, Akman S, Krutzik S, Paxton RJ, Sparkes RS, Doroshow J, Felsted RL, Glover CJ, Mohandas T, Bachur NR. Induction of a human carbonyl reductase gene located on chromosome 21. Biochimica Et Biophysica Acta. 1048: 149-55. PMID 2182121 DOI: 10.1016/0167-4781(90)90050-C  0.317
1990 Akman S, Doroshow J, Smith S. Formation of quadruplex DNA at a hot-spot for H2O2/Fe-mediated mutagenesis Free Radical Biology and Medicine. 9: 46. DOI: 10.1016/0891-5849(90)90333-E  0.339
1988 Margolin K, Akman S, Carr B, Leong L, Doroshow J. Etoposide (VP-16) and cytosine arabinoside in the treatment of relapsed small-cell lung cancer. American Journal of Clinical Oncology. 11: 499-501. PMID 2841844 DOI: 10.1097/00000421-198808000-00017  0.303
1987 Ross DD, Thompson BW, Joneckis CC, Akman SA, Schiffer CA. Studies of ara-C metabolism in acute leukemia Seminars in Oncology. 14: 182-191. PMID 3589693 DOI: 10.5555/Uri:Pii:0093775487900649  0.307
1986 Ross D, Thompson B, Joneckis C, Akman S, Schiffer C. Metabolism of ara-C by blast cells from patients with ANLL. Blood. 68: 76-82. DOI: 10.1182/Blood.V68.1.76.Bloodjournal68176  0.313
Show low-probability matches.