Year |
Citation |
Score |
2017 |
Routh ED, Creacy SD, Beerbower PE, Akman SA, Vaughn JP, Smaldino PJ. A G-quadruplex DNA-affinity Approach for Purification of Enzymatically Active G4 Resolvase1. Journal of Visualized Experiments : Jove. PMID 28362374 DOI: 10.3791/55496 |
0.328 |
|
2015 |
Swanner J, Mims J, Carroll DL, Akman SA, Furdui CM, Torti SV, Singh RN. Differential cytotoxic and radiosensitizing effects of silver nanoparticles on triple-negative breast cancer and non-triple-negative breast cells. International Journal of Nanomedicine. 10: 3937-53. PMID 26185437 DOI: 10.2147/Ijn.S80349 |
0.345 |
|
2015 |
Smaldino PJ, Routh ED, Kim JH, Giri B, Creacy SD, Hantgan RR, Akman SA, Vaughn JP. Mutational Dissection of Telomeric DNA Binding Requirements of G4 Resolvase 1 Shows that G4-Structure and Certain 3'-Tail Sequences Are Sufficient for Tight and Complete Binding. Plos One. 10: e0132668. PMID 26172836 DOI: 10.1371/Journal.Pone.0132668 |
0.337 |
|
2014 |
Cowherd S, Melin S, Akman S, Cole J, Lawrence J. Abstract CT302: A phase II clinical trial of weekly paclitaxel and carboplatin in combination with panitumumab in metastatic or recurrent breast cancer patients with triple negative disease Cancer Research. 74. DOI: 10.1158/1538-7445.Am2014-Ct302 |
0.301 |
|
2012 |
Akman SA, Adams M, Case D, Park G, Manderville RA. Mutagenicity of ochratoxin A and its hydroquinone metabolite in the SupF gene of the mutation reporter plasmid Ps189. Toxins. 4: 267-80. PMID 22606376 DOI: 10.3390/Toxins4040267 |
0.366 |
|
2011 |
Giri B, Smaldino PJ, Thys RG, Creacy SD, Routh ED, Hantgan RR, Lattmann S, Nagamine Y, Akman SA, Vaughn JP. G4 resolvase 1 tightly binds and unwinds unimolecular G4-DNA. Nucleic Acids Research. 39: 7161-78. PMID 21586581 DOI: 10.1093/Nar/Gkr234 |
0.364 |
|
2008 |
Creacy SD, Routh ED, Iwamoto F, Nagamine Y, Akman SA, Vaughn JP. G4 resolvase 1 binds both DNA and RNA tetramolecular quadruplex with high affinity and is the major source of tetramolecular quadruplex G4-DNA and G4-RNA resolving activity in HeLa cell lysates. The Journal of Biological Chemistry. 283: 34626-34. PMID 18842585 DOI: 10.1074/Jbc.M806277200 |
0.334 |
|
2008 |
Smith TR, Levine EA, Freimanis RI, Akman SA, Allen GO, Hoang KN, Liu-Mares W, Hu JJ. Polygenic model of DNA repair genetic polymorphisms in human breast cancer risk. Carcinogenesis. 29: 2132-8. PMID 18701435 DOI: 10.1093/Carcin/Bgn193 |
0.347 |
|
2007 |
Gajewski E, Gaur S, Akman SA, Matsumoto L, van Balgooy JN, Doroshow JH. Oxidative DNA base damage in MCF-10A breast epithelial cells at clinically achievable concentrations of doxorubicin. Biochemical Pharmacology. 73: 1947-56. PMID 17445777 DOI: 10.1016/J.Bcp.2007.03.022 |
0.412 |
|
2006 |
Upton DC, Wang X, Blans P, Perrino FW, Fishbein JC, Akman SA. Replication of N2-ethyldeoxyguanosine DNA adducts in the human embryonic kidney cell line 293. Chemical Research in Toxicology. 19: 960-7. PMID 16841965 DOI: 10.1021/Tx060084A |
0.685 |
|
2006 |
Upton DC, Wang X, Blans P, Perrino FW, Fishbein JC, Akman SA. Mutagenesis by exocyclic alkylamino purine adducts in Escherichia coli. Mutation Research. 599: 1-10. PMID 16488449 DOI: 10.1016/J.Mrfmmm.2005.12.014 |
0.681 |
|
2005 |
Vaughn JP, Creacy SD, Routh ED, Joyner-Butt C, Jenkins GS, Pauli S, Nagamine Y, Akman SA. The DEXH protein product of the DHX36 gene is the major source of tetramolecular quadruplex G4-DNA resolving activity in HeLa cell lysates. The Journal of Biological Chemistry. 280: 38117-20. PMID 16150737 DOI: 10.1074/Jbc.C500348200 |
0.394 |
|
2005 |
Hart LS, Yannone SM, Naczki C, Orlando JS, Waters SB, Akman SA, Chen DJ, Ornelles D, Koumenis C. The adenovirus E4orf6 protein inhibits DNA double strand break repair and radiosensitizes human tumor cells in an E1B-55K-independent manner. The Journal of Biological Chemistry. 280: 1474-81. PMID 15507430 DOI: 10.1074/Jbc.M409934200 |
0.401 |
|
2003 |
Perrino FW, Blans P, Harvey S, Gelhaus SL, McGrath C, Akman SA, Jenkins GS, LaCourse WR, Fishbein JC. The N2-ethylguanine and the O6-ethyl- and O6-methylguanine lesions in DNA: contrasting responses from the "bypass" DNA polymerase eta and the replicative DNA polymerase alpha. Chemical Research in Toxicology. 16: 1616-23. PMID 14680376 DOI: 10.1021/Tx034164F |
0.429 |
|
2003 |
Manderville RA, Wade Calcutt M, Dai J, Park G, Gillman IG, Noftle RE, Mohammed AK, Birincioglu M, Dizdaroglu M, Rodriguez H, Akman SA. Stoichiometric preference in copper-promoted oxidative DNA damage by ochratoxin A. Journal of Inorganic Biochemistry. 95: 87-96. PMID 12763652 DOI: 10.1016/S0162-0134(03)00104-1 |
0.347 |
|
2003 |
Manderville RA, Calcutt M, Dai J, Park G, Gillman IG, Noftle RE, Mohammed AK, Dizdaroglu M, Rodriguez H, Akman SA. Corrigendum to: “Stoichiometric preference in copper-promoted oxidative DNA damage by ochratoxin A” Journal of Inorganic Biochemistry. 97: 249. DOI: 10.1016/S0162-0134(03)00278-2 |
0.343 |
|
2001 |
Waters SB, Akman SA. A new assay to quantify in vivo repair of G:T mispairs by base excision repair Mutation Research - Dna Repair. 487: 109-119. PMID 11738937 DOI: 10.1016/S0921-8777(01)00112-4 |
0.317 |
|
2001 |
Doroshow JH, Synold TW, Somlo G, Akman SA, Gajewski E. Oxidative DNA base modifications in peripheral blood mononuclear cells of patients treated with high-dose infusional doxorubicin Blood. 97: 2839-2845. PMID 11313279 DOI: 10.1182/Blood.V97.9.2839 |
0.413 |
|
2000 |
Rodriguez H, Akman SA, Holmquist GP, Wilson GL, Driggers WJ, LeDoux SP. Mapping oxidative DNA damage using ligation-mediated polymerase chain reaction technology. Methods (San Diego, Calif.). 22: 148-56. PMID 11020329 DOI: 10.1006/Meth.2000.1055 |
0.382 |
|
2000 |
Akman SA, O'Connor TR, Rodriguez H. Mapping oxidative DNA damage and mechanisms of repair Annals of the New York Academy of Sciences. 899: 88-102. PMID 10863531 DOI: 10.1111/J.1749-6632.2000.Tb06178.X |
0.403 |
|
1999 |
Rodriguez H, Akman SA. Measurement of oxidative DNA damage in the human p53 and PGK1 gene at nucleotide resolution Annals of the New York Academy of Sciences. 893: 382-385. PMID 10672273 DOI: 10.1111/J.1749-6632.1999.Tb07861.X |
0.349 |
|
1999 |
Rodriguez H, Valentine MR, Holmquist GP, Akman SA, Termini J. Mapping of peroxyl radical induced damage on genomic DNA Biochemistry. 38: 16578-16588. PMID 10600120 DOI: 10.1021/Bi9918994 |
0.38 |
|
1998 |
Rodriguez H, Akman SA. Mapping oxidative DNA damage at nucleotide level Free Radical Research. 29: 499-510. PMID 10098455 DOI: 10.1080/10715769800300551 |
0.416 |
|
1998 |
Rodriguez H, Akman SA. Large scale isolation of genes as DNA fragment lengths by continuous elution electrophoresis through an agarose matrix Electrophoresis. 19: 646-652. PMID 9629891 DOI: 10.1002/Elps.1150190506 |
0.356 |
|
1998 |
Rodriguez H, Akman SA. Enhancing the sensitivity of LMPCR for mapping oxidative genomic DNA damage Free Radical Biology and Medicine. 25: S106. DOI: 10.1016/S0891-5849(98)90328-8 |
0.313 |
|
1998 |
Rodriguez H, Akman SA. Development of ligation-mediated PCR for mapping oxidative genomic DNA damage Free Radical Biology and Medicine. 25: S78. DOI: 10.1016/S0891-5849(98)90250-7 |
0.32 |
|
1997 |
Harrington C, Lan Y, Akman SA. The identification and characterization of a G4-DNA resolvase activity Journal of Biological Chemistry. 272: 24631-24636. PMID 9305932 DOI: 10.1074/Jbc.272.39.24631 |
0.392 |
|
1997 |
Rodriguez H, Drouin R, Holmquist GP, Akman SA. A hot spot for hydrogen peroxide-induced damage in the human hypoxia- inducible factor 1 binding site of the PGK 1 gene Archives of Biochemistry and Biophysics. 338: 207-212. PMID 9028873 DOI: 10.1006/Abbi.1996.9820 |
0.358 |
|
1997 |
Newman EM, Carroll M, Akman SA, Chow W, Coluzzi P, Hamasaki V, Leong LA, Margolin KA, Morgan RJ, Raschko JW, Shibata S, Somlo G, Tetef M, Yen Y, Ahn CW, et al. Pharmacokinetics and toxicity of 120-hour continuous-infusion hydroxyurea in patients with advanced solid tumors Cancer Chemotherapy and Pharmacology. 39: 254-258. PMID 8996529 DOI: 10.1007/S002800050569 |
0.304 |
|
1996 |
Akman SA, Sander F, Garbutt K. In vivo mutagenesis of the reporter plasmid pSP189 induced by exposure of host Ad293 cells to activated polymorphonuclear leukocytes. Carcinogenesis. 17: 2137-41. PMID 8895480 DOI: 10.1093/Carcin/17.10.2137 |
0.363 |
|
1996 |
Drouin R, Rodriguez H, Gao SW, Gebreyes Z, O'Connor TR, Holmquist GP, Akman SA. Cupric ion/ascorbate/hydrogen peroxide-induced DNA damage: DNA-bound copper ion primarily induces base modifications Free Radical Biology and Medicine. 21: 261-273. PMID 8855437 DOI: 10.1016/0891-5849(96)00037-8 |
0.384 |
|
1995 |
Altman SA, Zastawny TH, Randers-Eichhorn L, Cacciuttolo MA, Akman SA, Dizdaroglu M, Rao G. Formation of DNA-protein cross-links in cultured mammalian cells upon treatment with iron ions Free Radical Biology and Medicine. 19: 897-902. PMID 8582666 DOI: 10.1016/0891-5849(95)00095-F |
0.303 |
|
1995 |
Tetef M, Margolin K, Ahn C, Akman S, Chow W, Coluzzi P, Leong L, Morgan RJ, Raschko J, Shibata S. Mitomycin C and menadione for the treatment of advanced gastrointestinal cancers: a phase II trial. Journal of Cancer Research and Clinical Oncology. 121: 103-6. PMID 7883772 DOI: 10.1007/Bf01202221 |
0.301 |
|
1995 |
Margolin KA, Akman SA, Leong LA, Morgan RJ, Somlo G, Raschko JW, Ahn C, Doroshow JH. Phase I study of mitomycin C and menadione in advanced solid tumors Cancer Chemotherapy and Pharmacology. 36: 293-298. PMID 7628048 DOI: 10.1007/Bf00689046 |
0.301 |
|
1995 |
Rodriguez H, Drouin R, Holmquist GP, O'Connor TR, Boiteux S, Laval J, Doroshow JH, Akman SA. Mapping of copper/hydrogen peroxide-induced DNA damage at nucleotide resolution in human genomic DNA by ligation-mediated polymerase chain reaction Journal of Biological Chemistry. 270: 17633-17640. PMID 7615572 DOI: 10.1074/Jbc.270.29.17633 |
0.407 |
|
1994 |
Margolin KA, Green S, Osborne K, Doroshow JH, Akman SA, Leong LA, Morgan RJ, Raschko JW, Somlo G, Hutchins L, Upchurch C. Phase II trial of 5-fluorouracil and high-dose folinic acid as first- or second-line therapy for advanced breast cancer American Journal of Clinical Oncology: Cancer Clinical Trials. 17: 175-180. PMID 8141112 DOI: 10.1097/00000421-199404000-00018 |
0.309 |
|
1994 |
Somlo G, Doroshow JH, Forman SJ, Leong LA, Margolin KA, Morgan RJ, Raschko JW, Akman SA, Ahn C, Nagasawa S, Harrison J. High-dose doxorubicin, etoposide, and cyclophosphamide with stem cell reinfusion in patients with metastatic or high-risk primary breast cancer Cancer. 73: 1678-1685. PMID 7512436 DOI: 10.1002/1097-0142(19940315)73:6<1678::Aid-Cncr2820730621>3.0.Co;2-U |
0.31 |
|
1993 |
Akman SA, Kensler TW, Doroshow JH, Dizdaroglu M. Copper ion-mediated modification of bases in dna in vitro by benzoyl peroxide Carcinogenesis. 14: 1971-1974. PMID 8403227 DOI: 10.1093/Carcin/14.9.1971 |
0.359 |
|
1992 |
Margolin KA, Doroshow JH, Akman SA, Leong LA, Morgan RJ, Raschko JW, Somlo G, Blevins C. Effective initial therapy of advanced breast cancer with fluorouracil and high-dose, continuous infusion calcium leucovorin Journal of Clinical Oncology. 10: 1278-1283. PMID 1634917 DOI: 10.1200/Jco.1992.10.8.1278 |
0.305 |
|
1992 |
Akman SA, Doroshow JH, Kensler TW. Copper-dependent site-specific mutagenesis by benzoyl peroxide in the supf gene of the mutation reporter plasmid ps189 Carcinogenesis. 13: 1783-1787. PMID 1423838 DOI: 10.1093/Carcin/13.10.1783 |
0.388 |
|
1992 |
Akman SA, Doroshow JH, Burke TG, Dizdaroglu M. DNA base modifications induced in isolated human chromatin by NADH dehydrogenase-catalyzed reduction of doxorubicin Biochemistry. 31: 3500-3506. PMID 1313297 DOI: 10.1021/Bi00128A026 |
0.342 |
|
1991 |
Akman SA, Forrest GP, Doroshow JH, Dizdaroglu M. Mutation of potassium permanganate- and hydrogen peroxide-treated plasmid pZ189 replicating in CV-1 monkey kidney cells Mutation Research/Genetic Toxicology. 261: 123-130. PMID 1922155 DOI: 10.1016/0165-1218(91)90058-T |
0.374 |
|
1991 |
Akman SA. Quadruplex DNA formation in a region of the tRNA gene supF associated with hydrogen peroxide mediated mutations Biochemistry. 30: 8648-8653. PMID 1888727 DOI: 10.1021/Bi00099A022 |
0.34 |
|
1990 |
Akman SA, Doroshow JH, Dizdaroglu M. Base modifications in plasmid DNA caused by potassium permanganate Archives of Biochemistry and Biophysics. 282: 202-205. PMID 2221919 DOI: 10.1016/0003-9861(90)90105-8 |
0.337 |
|
1990 |
Forrest GL, Akman S, Krutzik S, Paxton RJ, Sparkes RS, Doroshow J, Felsted RL, Glover CJ, Mohandas T, Bachur NR. Induction of a human carbonyl reductase gene located on chromosome 21. Biochimica Et Biophysica Acta. 1048: 149-55. PMID 2182121 DOI: 10.1016/0167-4781(90)90050-C |
0.317 |
|
1990 |
Akman S, Doroshow J, Smith S. Formation of quadruplex DNA at a hot-spot for H2O2/Fe-mediated mutagenesis Free Radical Biology and Medicine. 9: 46. DOI: 10.1016/0891-5849(90)90333-E |
0.339 |
|
1988 |
Margolin K, Akman S, Carr B, Leong L, Doroshow J. Etoposide (VP-16) and cytosine arabinoside in the treatment of relapsed small-cell lung cancer. American Journal of Clinical Oncology. 11: 499-501. PMID 2841844 DOI: 10.1097/00000421-198808000-00017 |
0.303 |
|
1987 |
Ross DD, Thompson BW, Joneckis CC, Akman SA, Schiffer CA. Studies of ara-C metabolism in acute leukemia Seminars in Oncology. 14: 182-191. PMID 3589693 DOI: 10.5555/Uri:Pii:0093775487900649 |
0.307 |
|
1986 |
Ross D, Thompson B, Joneckis C, Akman S, Schiffer C. Metabolism of ara-C by blast cells from patients with ANLL. Blood. 68: 76-82. DOI: 10.1182/Blood.V68.1.76.Bloodjournal68176 |
0.313 |
|
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