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Ake T. Lu, Ph.D. - Publications

Affiliations: 
2000 University of California, Los Angeles, Los Angeles, CA 
Area:
Biostatistics Biology
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35 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Ying K, Liu H, Tarkhov AE, Sadler MC, Lu AT, Moqri M, Horvath S, Kutalik Z, Shen X, Gladyshev VN. Causality-enriched epigenetic age uncouples damage and adaptation. Nature Aging. PMID 38243142 DOI: 10.1038/s43587-023-00557-0  0.341
2023 Lee J, Zhang J, Flanagan M, Martinez JA, Cunniff C, Kucine N, Lu AT, Haghani A, Gordevičius J, Horvath S, Chang VY. Bloom syndrome patients and mice display accelerated epigenetic aging. Aging Cell. e13964. PMID 37594403 DOI: 10.1111/acel.13964  0.342
2023 Horvath S, Haghani A, Zoller JA, Lu AT, Ernst J, Pellegrini M, Jasinska AJ, Mattison JA, Salmon AB, Raj K, Horvath M, Paul KC, Ritz BR, Robeck TR, Spriggs M, et al. Pan-primate studies of age and sex. Geroscience. PMID 37493860 DOI: 10.1007/s11357-023-00878-3  0.325
2023 Zoller JA, Parasyraki E, Lu AT, Haghani A, Niehrs C, Horvath S. DNA methylation clocks for clawed frogs reveal evolutionary conservation of epigenetic aging. Geroscience. PMID 37270437 DOI: 10.1007/s11357-023-00840-3  0.35
2023 Parsons KM, Haghani A, Zoller JA, Lu AT, Fei Z, Ferguson SH, Garde E, Hanson MB, Emmons CK, Matkin CO, Young BG, Koski WR, Horvath S. DNA methylation based biomarkers for aging long-lived cetaceans. Molecular Ecology Resources. PMID 36994812 DOI: 10.1111/1755-0998.13791  0.303
2023 Dec E, Clement J, Cheng K, Church GM, Fossel MB, Rehkopf DH, Rosero-Bixby L, Kobor MS, Lin DT, Lu AT, Fei Z, Guo W, Chew YC, Yang X, Putra SED, et al. Centenarian clocks: epigenetic clocks for validating claims of exceptional longevity. Geroscience. PMID 36964402 DOI: 10.1007/s11357-023-00731-7  0.309
2023 Bernabeu E, McCartney DL, Gadd DA, Hillary RF, Lu AT, Murphy L, Wrobel N, Campbell A, Harris SE, Liewald D, Hayward C, Sudlow C, Cox SR, Evans KL, Horvath S, et al. Refining epigenetic prediction of chronological and biological age. Genome Medicine. 15: 12. PMID 36855161 DOI: 10.1186/s13073-023-01161-y  0.311
2022 Nannini DR, Zheng Y, Joyce BT, Gao T, Liu L, Jacobs DR, Schreiner P, Liu C, Horvath S, Lu AT, Yaffe K, Sidney S, Greenland P, Lloyd-Jones DM, Hou L. Marijuana use and DNA methylation-based biological age in young adults. Clinical Epigenetics. 14: 134. PMID 36289503 DOI: 10.1186/s13148-022-01359-8  0.308
2022 Mozhui K, Lu AT, Li CZ, Haghani A, Sandoval-Sierra JV, Wu Y, Williams RW, Horvath S. Genetic loci and metabolic states associated with murine epigenetic aging. Elife. 11. PMID 35389339 DOI: 10.7554/eLife.75244  0.37
2021 Roberts JD, Vittinghoff E, Lu AT, Alonso A, Wang B, Sitlani CM, Mohammadi-Shemirani P, Fornage M, Kornej J, Brody JA, Arking DE, Lin H, Heckbert SR, Prokic I, Ghanbari M, et al. Epigenetic Age and the Risk of Incident Atrial Fibrillation. Circulation. PMID 34587750 DOI: 10.1161/CIRCULATIONAHA.121.056456  0.335
2021 Joyce B, Gao T, Zheng Y, Ma J, Hwang SJ, Liu L, Nannini DR, Horvath S, Lu AT, Allen NB, Jacobs DR, Gross M, Krefman AE, Ning H, Liu K, et al. Epigenetic Age Acceleration Reflects Long-Term Cardiovascular Health. Circulation Research. PMID 34428927 DOI: 10.1161/CIRCRESAHA.121.318965  0.335
2021 Sugrue VJ, Zoller JA, Narayan P, Lu AT, Ortega-Recalde OJ, Grant MJ, Bawden CS, Rudiger SR, Haghani A, Bond DM, Hore RR, Garratt M, Sears KE, Wang N, Yang XW, et al. Castration delays epigenetic aging and feminizes DNA methylation at androgen-regulated loci. Elife. 10. PMID 34227937 DOI: 10.7554/eLife.64932  0.313
2021 McCartney DL, Min JL, Richmond RC, Lu AT, Sobczyk MK, Davies G, Broer L, Guo X, Jeong A, Jung J, Kasela S, Katrinli S, Kuo PL, Matias-Garcia PR, Mishra PP, et al. Genome-wide association studies identify 137 genetic loci for DNA methylation biomarkers of aging. Genome Biology. 22: 194. PMID 34187551 DOI: 10.1186/s13059-021-02398-9  0.321
2021 Robeck TR, Fei Z, Lu AT, Haghani A, Jourdain E, Zoller JA, Li CZ, Steinman KJ, DiRocco S, Schmitt T, Osborn S, Van Bonn B, Katsumata E, Mergl J, Almunia J, et al. Multi-species and multi-tissue methylation clocks for age estimation in toothed whales and dolphins. Communications Biology. 4: 642. PMID 34059764 DOI: 10.1038/s42003-021-02179-x  0.315
2021 Nachun D, Lu AT, Bick AG, Natarajan P, Weinstock J, Szeto MD, Kathiresan S, Abecasis G, Taylor KD, Guo X, Tracy R, Durda P, Liu Y, Johnson C, Rich SS, et al. Clonal hematopoiesis associated with epigenetic aging and clinical outcomes. Aging Cell. e13366. PMID 34050697 DOI: 10.1111/acel.13366  0.365
2021 Wilkinson GS, Adams DM, Haghani A, Lu AT, Zoller J, Breeze CE, Arnold BD, Ball HC, Carter GG, Cooper LN, Dechmann DKN, Devanna P, Fasel NJ, Galazyuk AV, Günther L, et al. DNA methylation predicts age and provides insight into exceptional longevity of bats. Nature Communications. 12: 1615. PMID 33712580 DOI: 10.1038/s41467-021-21900-2  0.331
2020 McCrory C, Fiorito G, Hernandez B, Polidoro S, O'Halloran AM, Hever A, Ni Cheallaigh C, Lu AT, Horvath S, Vineis P, Kenny RA. GrimAge outperforms other epigenetic clocks in the prediction of age-related clinical phenotypes and all-cause mortality. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 33211845 DOI: 10.1093/gerona/glaa286  0.355
2020 Yan Q, Paul KC, Lu AT, Kusters C, Binder AM, Horvath S, Ritz B. Epigenetic mutation load is weakly correlated with epigenetic age acceleration. Aging. 12. PMID 32991324 DOI: 10.18632/aging.103950  0.336
2020 Lu AT, Narayan P, Grant MJ, Langfelder P, Wang N, Kwak S, Wilkinson H, Chen RZ, Chen J, Simon Bawden C, Rudiger SR, Ciosi M, Chatzi A, Maxwell A, Hore TA, et al. DNA methylation study of Huntington's disease and motor progression in patients and in animal models. Nature Communications. 11: 4529. PMID 32913184 DOI: 10.1038/S41467-020-18255-5  0.363
2019 Gibson J, Russ TC, Clarke TK, Howard DM, Hillary RF, Evans KL, Walker RM, Bermingham ML, Morris SW, Campbell A, Hayward C, Murray AD, Porteous DJ, Horvath S, Lu AT, et al. A meta-analysis of genome-wide association studies of epigenetic age acceleration. Plos Genetics. 15: e1008104. PMID 31738745 DOI: 10.1371/Journal.Pgen.1008104  0.457
2019 Lee Y, Sun D, Ori APS, Lu AT, Seeboth A, Harris SE, Deary IJ, Marioni RE, Soerensen M, Mengel-From J, Hjelmborg J, Christensen K, Wilson JG, Levy D, Reiner AP, et al. Epigenome-wide association study of leukocyte telomere length. Aging. 11. PMID 31461406 DOI: 10.18632/aging.102230  0.357
2019 Horvath S, Lu AT, Cohen H, Raj K. Rapamycin retards epigenetic ageing of keratinocytes independently of its effects on replicative senescence, proliferation and differentiation. Aging. PMID 31136303 DOI: 10.18632/aging.101976  0.308
2019 Lu AT, Quach A, Wilson JG, Reiner AP, Aviv A, Raj K, Hou L, Baccarelli AA, Li Y, Stewart JD, Whitsel EA, Assimes TL, Ferrucci L, Horvath S. DNA methylation GrimAge strongly predicts lifespan and healthspan. Aging. PMID 30669119 DOI: 10.18632/aging.101684  0.309
2019 Lu AT, Horvath S. Epigenetic Predictors Of Lifespan And Healthspan Innovation in Aging. 3. DOI: 10.1093/Geroni/Igz038.130  0.333
2018 Levine ME, Lu AT, Quach A, Chen BH, Assimes TL, Bandinelli S, Hou L, Baccarelli AA, Stewart JD, Li Y, Whitsel EA, Wilson JG, Reiner AP, Aviv A, Lohman K, et al. An epigenetic biomarker of aging for lifespan and healthspan. Aging. PMID 29676998 DOI: 10.18632/aging.101414  0.346
2018 Lu AT, Xue L, Salfati EL, Chen BH, Ferrucci L, Levy D, Joehanes R, Murabito JM, Kiel DP, Tsai PC, Yet I, Bell JT, Mangino M, Tanaka T, McRae AF, et al. GWAS of epigenetic aging rates in blood reveals a critical role for TERT. Nature Communications. 9: 387. PMID 29374233 DOI: 10.1038/S41467-017-02697-5  0.459
2018 Levine M, Lu A, Quach A, Chen B, Baccarelli A, Whitsel E, Ferrucci L, Horvath S. An Epigenetic Clock For Aging And Life Expectancy Innovation in Aging. 2: 61-61. DOI: 10.1093/Geroni/Igy023.231  0.404
2017 Lu AT, Hannon E, Levine ME, Crimmins EM, Lunnon K, Mill J, Geschwind DH, Horvath S. Genetic architecture of epigenetic and neuronal ageing rates in human brain regions. Nature Communications. 8: 15353. PMID 28516910 DOI: 10.1038/Ncomms15353  0.398
2017 Quach A, Levine ME, Tanaka T, Lu AT, Chen BH, Ferrucci L, Ritz B, Bandinelli S, Neuhouser ML, Beasley JM, Snetselaar L, Wallace RB, Tsao PS, Absher D, Assimes TL, et al. Epigenetic clock analysis of diet, exercise, education, and lifestyle factors. Aging. PMID 28198702 DOI: 10.18632/aging.101168  0.306
2016 Chen BH, Marioni RE, Colicino E, Peters MJ, Ward-Caviness CK, Tsai PC, Roetker NS, Just AC, Demerath EW, Guan W, Bressler J, Fornage M, Studenski S, Vandiver AR, Moore AZ, ... ... Lu AT, et al. DNA methylation-based measures of biological age: meta-analysis predicting time to death. Aging. PMID 27690265 DOI: 10.18632/aging.101020  0.354
2016 Levine ME, Lu AT, Chen BH, Hernandez DG, Singleton AB, Ferrucci L, Bandinelli S, Salfati E, Manson JE, Quach A, Kusters CD, Kuh D, Wong A, Teschendorff AE, Widschwendter M, et al. Menopause accelerates biological aging. Proceedings of the National Academy of Sciences of the United States of America. PMID 27457926 DOI: 10.1073/Pnas.1604558113  0.445
2016 Lu AT, Hannon E, Levine ME, Hao K, Crimmins EM, Lunnon K, Kozlenkov A, Mill J, Dracheva S, Horvath S. Genetic variants near MLST8 and DHX57 affect the epigenetic age of the cerebellum. Nature Communications. 7: 10561. PMID 26830004 DOI: 10.1038/Ncomms10561  0.438
2015 Horvath S, Mah V, Lu AT, Woo JS, Choi OW, Jasinska AJ, Riancho JA, Tung S, Coles NS, Braun J, Vinters HV, Coles LS. The cerebellum ages slowly according to the epigenetic clock. Aging. 7: 294-306. PMID 26000617  0.363
2014 Wang RT, Silverstein Fadlon CA, Ulm JW, Jankovic I, Eskin A, Lu A, Rangel Miller V, Cantor RM, Li N, Elashoff R, Martin AS, Peay HL, Halnon N, Nelson SF. Online self-report data for duchenne muscular dystrophy confirms natural history and can be used to assess for therapeutic benefits. Plos Currents. 6. PMID 25635234 DOI: 10.1371/Currents.Md.E1E8F2Be7C949F9Ffe81Ec6Fca1Cce6A  0.331
2012 Eggert SL, Huyck KL, Somasundaram P, Kavalla R, Stewart EA, Lu AT, Painter JN, Montgomery GW, Medland SE, Nyholt DR, Treloar SA, Zondervan KT, Heath AC, Madden PA, Rose L, et al. Genome-wide linkage and association analyses implicate FASN in predisposition to Uterine Leiomyomata. American Journal of Human Genetics. 91: 621-8. PMID 23040493 DOI: 10.1016/J.Ajhg.2012.08.009  0.337
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