William T. Hu - Publications

Affiliations: 
Neurology Emory University, Atlanta, GA 
Area:
Frontotemporal dementia, Alzheimer's disease, biomarkers

110 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Butts B, Huang H, Hu WT, Kehoe PG, Miners JS, Verble DD, Zetterberg H, Zhao L, Trotti LM, Benameur K, Scorr LM, Wharton W. sPDGFRβ and neuroinflammation are associated with AD biomarkers and differ by race: The ASCEND Study. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 37933404 DOI: 10.1002/alz.13457  0.389
2023 Giannisis A, Al-Grety A, Carlsson H, Howell JC, Hu WT, Kultima K, Nielsen HM. Correction: Plasma apolipoprotein E levels, isoform composition, and dimer profile in relation to plasma lipids in racially diverse patients with Alzheimer's disease and mild cognitive impairment. Alzheimer's Research & Therapy. 15: 160. PMID 37759231 DOI: 10.1186/s13195-023-01306-6  0.709
2023 Giannisis A, Al-Grety A, Carlsson H, Howell JC, Hu WT, Kultima K, Nielsen HM. Plasma apolipoprotein E levels, isoform composition, and dimer profile in relation to plasma lipids in racially diverse patients with Alzheimer's disease and mild cognitive impairment. Alzheimer's Research & Therapy. 15: 119. PMID 37400888 DOI: 10.1186/s13195-023-01262-1  0.737
2023 Hu WT, Nayyar A, Kaluzova M. Charting the Next Road Map for CSF Biomarkers in Alzheimer's Disease and Related Dementias. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. PMID 37378862 DOI: 10.1007/s13311-023-01370-8  0.459
2023 van der Ende EL, In 't Veld SGJG, Hanskamp I, van der Lee S, Dijkstra JIR, Hok-A-Hin YS, Blujdea ER, van Swieten JC, Irwin DJ, Chen-Plotkin A, Hu WT, Lemstra AW, Pijnenburg YAL, van der Flier WM, Del Campo M, et al. CSF proteomics in autosomal dominant Alzheimer's disease highlights parallels with sporadic disease. Brain : a Journal of Neurology. PMID 37348871 DOI: 10.1093/brain/awad213  0.659
2022 Del Campo M, Peeters CFW, Johnson ECB, Vermunt L, Hok-A-Hin YS, van Nee M, Chen-Plotkin A, Irwin DJ, Hu WT, Lah JJ, Seyfried NT, Dammer EB, Herradon G, Meeter LH, van Swieten J, et al. CSF proteome profiling across the Alzheimer's disease spectrum reflects the multifactorial nature of the disease and identifies specific biomarker panels. Nature Aging. 2: 1040-1053. PMID 37118088 DOI: 10.1038/s43587-022-00300-1  0.748
2022 Chan AWS, Cho IK, Li CX, Zhang X, Patel S, Rusnak R, Raper J, Bachevalier J, Moran SP, Chi T, Cannon KH, Hunter CE, Martin RC, Xiao H, Yang SH, ... ... Hu WT, et al. Cerebral Aβ deposition in an Aβ-precursor protein-transgenic rhesus monkey. Aging Brain. 2. PMID 36589695 DOI: 10.1016/j.nbas.2022.100044  0.522
2022 Hok-A-Hin YS, Hoozemans JJM, Hu WT, Wouters D, Howell JC, Rábano A, van der Flier WM, Pijnenburg YAL, Teunissen CE, Del Campo M. YKL-40 changes are not detected in post-mortem brain of patients with Alzheimer's disease and frontotemporal lobar degeneration. Alzheimer's Research & Therapy. 14: 100. PMID 35879733 DOI: 10.1186/s13195-022-01039-y  0.732
2022 Hassan A, Mittal SO, Hu WT, Josephs KA, Sorenson EJ, Ahlskog JE. Does limited EMG denervation in early primary lateral sclerosis predict amyotrophic lateral sclerosis? Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 1-8. PMID 35170382 DOI: 10.1080/21678421.2022.2039714  0.368
2021 Wharton W, Jeong L, Ni L, Bay AA, Shin RJ, McCullough LE, Silverstein H, Hart AR, Swieboda D, Hu W, Hackney ME. A Pilot randomized clinical trial of adapted tango to improve cognition and psychosocial function in African American women with family history of Alzheimer's disease (ACT trial). Cerebral Circulation - Cognition and Behavior. 2: 100018. PMID 36324714 DOI: 10.1016/j.cccb.2021.100018  0.333
2021 Levey AI, Qiu D, Zhao L, Hu WT, Duong DM, Higginbotham L, Dammer EB, Seyfried NT, Wingo TS, Hales CM, Gámez Tansey M, Goldstein DS, Abrol A, Calhoun VD, Goldstein FC, et al. A phase II study repurposing atomoxetine for neuroprotection in mild cognitive impairment. Brain : a Journal of Neurology. PMID 34919634 DOI: 10.1093/brain/awab452  0.56
2021 Campo MD, Pijnenburg YAL, Chen-Plotkin A, Irwin DJ, Grossman M, Twaalfhoven HAM, Hu WT, Meeter LH, van Swieten J, Vermunt L, Martens F, Heijboer AC, Teunissen CE. Sex Hormone-Binding Globulin (SHBG) in Cerebrospinal Fluid Does Not Discriminate between the Main FTLD Pathological Subtypes but Correlates with Cognitive Decline in FTLD Tauopathies. Biomolecules. 11. PMID 34680117 DOI: 10.3390/biom11101484  0.692
2021 Hu WT, Ozturk T, Kollhoff A, Wharton W, Christina Howell J. Higher CSF sTNFR1-related proteins associate with better prognosis in very early Alzheimer's disease. Nature Communications. 12: 4001. PMID 34183654 DOI: 10.1038/s41467-021-24220-7  0.411
2021 Hu WT, Ozturk T, Kollhoff A, Wharton W, Christina Howell J. Higher CSF sTNFR1-related proteins associate with better prognosis in very early Alzheimer's disease. Nature Communications. 12: 4001. PMID 34183654 DOI: 10.1038/s41467-021-24220-7  0.411
2021 Hassan A, Mittal SO, Hu WT, Josephs KA, Sorenson EJ, Ahlskog JE. Natural History of Pure Primary Lateral Sclerosis. Neurology. PMID 33637635 DOI: 10.1212/WNL.0000000000011771  0.331
2020 Yilmaz A, Ustun I, Ugur Z, Akyol S, Hu WT, Fiandaca MS, Mapstone M, Federoff H, Maddens M, Graham SF. A Community-Based Study Identifying Metabolic Biomarkers of Mild Cognitive Impairment and Alzheimer's Disease Using Artificial Intelligence and Machine Learning. Journal of Alzheimer's Disease : Jad. PMID 33164929 DOI: 10.3233/JAD-200305  0.406
2020 Denny A, Streitz M, Stock K, Balls-Berry JE, Barnes LL, Byrd GS, Croff R, Gao S, Glover CM, Hendrie HC, Hu WT, Manly JJ, Moulder KL, Stark S, Thomas SB, et al. Perspective on the "African American participation in Alzheimer disease research: Effective strategies" workshop, 2018. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 33034414 DOI: 10.1002/Alz.12160  0.397
2020 Hu WT, Howell JC, Ozturk T, Benameur K, Bassit LC, Ramonell R, Cashman KS, Pirmohammed S, Roback JD, Marconi VC, Yang I, Mac VV, Smith D, Sanz I, Wharton W, et al. Antibody Profiles According to Mild or Severe SARS-CoV-2 Infection, Atlanta, Georgia, USA, 2020. Emerging Infectious Diseases. 26. PMID 32857691 DOI: 10.3201/Eid2612.203334  0.705
2020 Benameur K, Agarwal A, Auld SC, Butters MP, Webster AS, Ozturk T, Howell JC, Bassit LC, Velasquez A, Schinazi RF, Mullins ME, Hu WT. Encephalopathy and Encephalitis Associated with Cerebrospinal Fluid Cytokine Alterations and Coronavirus Disease, Atlanta, Georgia, USA, 2020. Emerging Infectious Diseases. 26. PMID 32487282 DOI: 10.3201/Eid2609.202122  0.71
2020 Kumar VV, Huang H, Zhao L, Verble DD, Nutaitis A, Tharwani SD, Brown AL, Zetterberg H, Hu W, Shin R, Kehoe PG, Quyyumi A, Nocera J, Kippels A, Wharton W. Baseline Results: The Association between Cardiovascular Risk and Preclinical Alzheimer's Disease Pathology (ASCEND) Study. Journal of Alzheimer's Disease : Jad. PMID 32280088 DOI: 10.3233/Jad-191103  0.449
2020 Misiura MB, Howell JC, Wu J, Qiu D, Parker MW, Turner JA, Hu WT. Race modifies default mode connectivity in Alzheimer's disease. Translational Neurodegeneration. 9: 8. PMID 32099645 DOI: 10.1186/S40035-020-0186-4  0.791
2019 Niedzwiecki MM, Walker DI, Howell JC, Watts KD, Jones DP, Miller GW, Hu WT. High-resolution metabolomic profiling of Alzheimer's disease in plasma. Annals of Clinical and Translational Neurology. PMID 31828981 DOI: 10.1002/Acn3.50956  0.768
2019 Josephs KA, Mackenzie I, Frosch MP, Bigio EH, Neumann M, Arai T, Dugger BN, Ghetti B, Grossman M, Hasegawa M, Herrup K, Holton J, Jellinger K, Lashley T, McAleese KE, ... ... Hu W, et al. LATE to the PART-y. Brain : a Journal of Neurology. PMID 31359030 DOI: 10.1093/Brain/Awz224  0.584
2019 Wharton W, Kollhoff AL, Gangishetti U, Verble DD, Upadhya S, Zetterberg H, Kumar V, Watts KD, Kippels AJ, Gearing M, Howell JC, Parker MW, Hu WT. IL-9 alterations linked to Alzheimer's disease in African Americans. Annals of Neurology. PMID 31271450 DOI: 10.1002/Ana.25543  0.831
2019 Ozturk T, Kollhoff A, Anderson AM, Christina Howell J, Loring DW, Waldrop-Valverde D, Franklin D, Letendre S, Tyor WR, Hu WT. Linked CSF reduction of phosphorylated tau and IL-8 in HIV associated neurocognitive disorder. Scientific Reports. 9: 8733. PMID 31217522 DOI: 10.1038/S41598-019-45418-2  0.407
2019 Hu WT, Howell JC, Ozturk T, Gangishetti U, Kollhoff AL, Hatcher-Martin JM, Anderson AM, Tyor WR. CSF Cytokines in Aging, Multiple Sclerosis, and Dementia. Frontiers in Immunology. 10: 480. PMID 30930904 DOI: 10.3389/Fimmu.2019.00480  0.775
2019 Bliwise D, Trotti LM, Wood-Siverio C, Hu W. 0712 APOE4, But Not Desaturation Index, Is Associated with Dementia Severity In A Memory Clinic Population Sleep. 42: A285-A286. DOI: 10.1093/Sleep/Zsz067.710  0.312
2019 Levey AI, Lah JJ, Hu WT, Wingo TS, Hales CM, Manzanares C, Tansey MG, Goldstein DS, Zhao L, Galasko DR, Edland SD, Hanfelt J, Weinshenker D. O4-11-05: A PROOF OF CONCEPT PHASE II STUDY REPURPOSING ATOMOXETINE FOR NEUROPROTECTION IN MILD COGNITIVE IMPAIRMENT: EVIDENCE FOR TARGET ENGAGEMENT, REGULATION OF CSF BIOMARKERS, AND DISEASE-MODIFYING POTENTIAL Alzheimer's & Dementia. 15: P1263-P1264. DOI: 10.1016/J.Jalz.2019.06.4804  0.53
2019 Wharton W, Kollhoff AL, Gangishetti U, Verble DD, Pak H, Shin R, Huang H, Upadhya S, Zetterberg H, Kumar V, Watts KD, Kippels AJ, Gearing M, Howell J, Parker MW, ... ... Hu WT, et al. O2-02-01: DIFFERENT CSF TOTAL AND PHOSPHORYLATED TAU, BUT NOT Aβ, IN OLDER AND YOUNGER AFRICAN AMERICANS AND WHITES Alzheimer's & Dementia. 15: P535-P535. DOI: 10.1016/J.Jalz.2019.06.4457  0.79
2019 Misiura M, Howell JC, Parker MW, Turner J, Hu WT. P4-277: DISPARATE RACIAL RELATIONSHIPS BETWEEN COGNITIVE IMPAIRMENT AND FUNCTIONAL CONNECTIVITY IN DEFAULT MODE NETWORK SUBSYSTEMS Alzheimer's & Dementia. 15: P1389-P1389. DOI: 10.1016/J.Jalz.2019.06.3946  0.677
2019 Hu WT, Wharton W, Kollhoff AL, Gangishetti U, Verble DD, Upadhya S, Zetterberg H, Kumar V, Huang H, Watts KD, Kippels AJ, Gearing M, Howell JC, Parker MW. P3-620: IL-9 ALTERATIONS ARE LINKED TO ALZHEIMER'S DISEASE IN AFRICAN AMERICANS Alzheimer's & Dementia. 15: P1214-P1214. DOI: 10.1016/J.Jalz.2019.06.3658  0.799
2019 Huang H, Hu WT, Zhao L, Shin R, Verble DD, Howell JC, Pak H, Tharwani S, Kumar V, Flatt J, Anderson JG, Wharton W. P2-598: SUBJECTIVE AND BIOLOGICAL MARKERS OF STRESS IN MIDDLE-AGED CAUCASIAN AND AFRICAN AMERICAN ALZHEIMER'S DISEASE FAMILIES Alzheimer's & Dementia. 15: P853-P853. DOI: 10.1016/J.Jalz.2019.06.3007  0.373
2018 French CD, Willoughby RE, Pan A, Wong SJ, Foley JF, Wheat LJ, Fernandez J, Encarnacion R, Ondrush JM, Fatteh N, Paez A, David D, Javaid W, Amzuta IG, Neilan AM, ... ... Hu WT, et al. NMR metabolomics of cerebrospinal fluid differentiates inflammatory diseases of the central nervous system. Plos Neglected Tropical Diseases. 12: e0007045. PMID 30557317 DOI: 10.1371/Journal.Pntd.0007045  0.379
2018 Allen JW, Yazdani M, Kang J, Magnussen MJ, Qiu D, Hu W. Patients with Mild Cognitive Impairment May be Stratified by Advanced Diffusion Metrics and Neurocognitive Testing. Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging. PMID 30548151 DOI: 10.1111/Jon.12588  0.317
2018 Del Campo M, Galimberti D, Elias N, Boonkamp L, Pijnenburg YA, van Swieten JC, Watts K, Paciotti S, Beccari T, Hu W, Teunissen CE. Novel CSF biomarkers to discriminate FTLD and its pathological subtypes. Annals of Clinical and Translational Neurology. 5: 1163-1175. PMID 30349851 DOI: 10.1002/Acn3.629  0.457
2018 Gangishetti U, Christina Howell J, Perrin RJ, Louneva N, Watts KD, Kollhoff A, Grossman M, Wolk DA, Shaw LM, Morris JC, Trojanowski JQ, Fagan AM, Arnold SE, Hu WT. Non-beta-amyloid/tau cerebrospinal fluid markers inform staging and progression in Alzheimer's disease. Alzheimer's Research & Therapy. 10: 98. PMID 30253800 DOI: 10.1186/S13195-018-0426-3  0.833
2018 Kollhoff AL, Howell JC, Hu WT. Automation vs. Experience: Measuring Alzheimer's Beta-Amyloid 1-42 Peptide in the CSF. Frontiers in Aging Neuroscience. 10: 253. PMID 30186152 DOI: 10.3389/Fnagi.2018.00253  0.742
2018 Kamara DM, Gangishetti U, Gearing M, Willis-Parker M, Zhao L, Hu WT, Walker LC. Cerebral Amyloid Angiopathy: Similarity in African-Americans and Caucasians with Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 29614657 DOI: 10.3233/Jad-170954  0.826
2018 Trotti LM, Keating G, Bliwise DL, Hu W. 1009 Dementia And Dreaming: Hypocretin Is A Trans-diagnostic Biomarker Of Nightmares In Dementia Sleep. 41: A374-A375. DOI: 10.1093/Sleep/Zsy061.1008  0.428
2017 Howell JC, Watts KD, Parker MW, Wu J, Kollhoff A, Wingo TS, Dorbin CD, Qiu D, Hu WT. Race modifies the relationship between cognition and Alzheimer's disease cerebrospinal fluid biomarkers. Alzheimer's Research & Therapy. 9: 88. PMID 29096697 DOI: 10.1186/S13195-017-0315-1  0.789
2017 Hu WT. No doubts about dementia advocacy. The Lancet. Psychiatry. PMID 28986233 DOI: 10.1016/S2215-0366(17)30373-5  0.4
2017 Gendron TF, Daughrity LM, Heckman MG, Diehl NN, Wuu J, Miller TM, Pastor P, Trojanowski JQ, Grossman M, Berry JD, Hu WT, Ratti A, Benatar M, Silani V, Glass JD, et al. Phosphorylated neurofilament heavy chain: A biomarker of survival for C9ORF72-associated amyotrophic lateral sclerosis. Annals of Neurology. PMID 28628244 DOI: 10.1002/Ana.24980  0.591
2017 Gendron TF, Chew J, Stankowski JN, Hayes LR, Zhang YJ, Prudencio M, Carlomagno Y, Daughrity LM, Jansen-West K, Perkerson EA, O'Raw A, Cook C, Pregent L, Belzil V, van Blitterswijk M, ... ... Hu WT, et al. Poly(GP) proteins are a useful pharmacodynamic marker for C9ORF72-associated amyotrophic lateral sclerosis. Science Translational Medicine. 9. PMID 28356511 DOI: 10.1126/Scitranslmed.Aai7866  0.51
2017 Tsvetkova DZ, Bergquist SH, Parker MW, Jarrett TL, Howell JC, Watts KD, Kollhoff A, Roberts DL, Hu WT. Fear and Uncertainty Do Not Influence Reported Willingness to Undergo Lumbar Punctures in a U.S. Multi-Cultural Cohort. Frontiers in Aging Neuroscience. 9: 22. PMID 28239349 DOI: 10.3389/Fnagi.2017.00022  0.671
2017 Hayward D, Howell J, Hu WT. WHAT IS DEMENTIA FRIENDLY? DEVELOPMENT AND VALIDATION OF A NOVEL TOOL TO MEASURE STIGMA ASSOCIATED WITH DEMENTIA Alzheimer's & Dementia. 13: P1514. DOI: 10.1016/J.Jalz.2017.07.633  0.716
2017 Gangishetti U, Perrin RJ, Arnold SE, Fagan AM, Morris JC, Trojanowski JQ, Hu WT. VALIDATING NON-AMYLOID, NON-TAU CSF BIOMARKERS FOR ALZHEIMER'S DISEASE IN THE PRE-SYMPTOMATIC, MCI, AND DEMENTIA STAGES: A MULTI-CENTER STUDY Alzheimer's & Dementia. 13: P1513-P1514. DOI: 10.1016/J.Jalz.2017.07.632  0.836
2016 Howell JC, Parker MW, Watts KD, Kollhoff A, Tsvetkova DZ, Hu WT. Research Lumbar Punctures among African Americans and Caucasians: Perception Predicts Experience. Frontiers in Aging Neuroscience. 8: 296. PMID 27994549 DOI: 10.3389/Fnagi.2016.00296  0.682
2016 Holler CJ, Taylor G, McEachin ZT, Deng Q, Watkins WJ, Hudson K, Easley CA, Hu WT, Hales CM, Rossoll W, Bassell GJ, Kukar T. Trehalose upregulates progranulin expression in human and mouse models of GRN haploinsufficiency: a novel therapeutic lead to treat frontotemporal dementia. Molecular Neurodegeneration. 11: 46. PMID 27341800 DOI: 10.1186/S13024-016-0114-3  0.41
2016 Hu WT, Watts KD, Tailor P, Nguyen TP, Howell JC, Lee RC, Seyfried NT, Gearing M, Hales CM, Levey AI, Lah JJ, Lee EK. CSF complement 3 and factor H are staging biomarkers in Alzheimer's disease. Acta Neuropathologica Communications. 4: 14. PMID 26887322 DOI: 10.1186/S40478-016-0277-8  0.826
2016 Campo MD, Koel-Simmelink MJ, Elias N, Boonkamp L, Galimberti D, Hu WT, Teunissen CE. Novel Csf Biomarkers Discriminating Ftld-Tdp From Non-Demented Controls Alzheimers & Dementia. 12: 388. DOI: 10.1016/J.Jalz.2016.06.731  0.36
2016 Howell JC, Parker MW, Watts KD, Wingo T, Hu WT. O1-11-06: Lower Prevalence of Abnormal CSF Alzheimer’s Biomarkers Among African Americans than Caucasians with Normal Cognition or Cognitive Impairment Alzheimer's & Dementia. 12: P204-P205. DOI: 10.1016/J.Jalz.2016.06.357  0.709
2016 Parker MW, Howell J, Dorbin CD, Mouton CP, Hu WT. P4-130: Recruiting Older African Americans for Alzheimer′s Disease Biomarker Study Involving Lumbar Punctures in Two Centers Alzheimer's & Dementia. 12: P1063-P1063. DOI: 10.1016/J.Jalz.2016.06.2221  0.717
2016 Watts KD, Howell J, Herrera P, Lee RC, Hu WT. P4-123: Resolving Conflicting CSF Biomarker Information in Alzheimer′s Disease Alzheimer's & Dementia. 12: P1061-P1061. DOI: 10.1016/J.Jalz.2016.06.2214  0.719
2016 Niedzwiecki MM, Walker D, Watts KD, Hu WT. P3-156: Validating Plasma Metabolomics Signatures of Alzheimer’s Disease Alzheimer's & Dementia. 12: P879-P879. DOI: 10.1016/J.Jalz.2016.06.1816  0.334
2015 Leung YY, Toledo JB, Nefedov A, Polikar R, Raghavan N, Xie SX, Farnum M, Schultz T, Baek Y, Deerlin VV, Hu WT, Holtzman DM, Fagan AM, Perrin RJ, Grossman M, et al. Identifying amyloid pathology-related cerebrospinal fluid biomarkers for Alzheimer's disease in a multicohort study. Alzheimer's & Dementia (Amsterdam, Netherlands). 1: 339-348. PMID 26693175 DOI: 10.1016/J.Dadm.2015.06.008  0.739
2015 Howell JC, Soyinka O, Parker M, Jarrett TL, Roberts DL, Dorbin CD, Hu WT. Knowledge and Attitudes in Alzheimer's Disease in a Cohort of Older African Americans and Caucasians. American Journal of Alzheimer's Disease and Other Dementias. PMID 26646115 DOI: 10.1177/1533317515619037  0.745
2015 Toledo JB, Zetterberg H, van Harten AC, Glodzik L, Martinez-Lage P, Bocchio-Chiavetto L, Rami L, Hansson O, Sperling R, Engelborghs S, Osorio RS, Vanderstichele H, Vandijck M, Hampel H, Teipl S, ... ... Hu WT, et al. Alzheimer's disease cerebrospinal fluid biomarker in cognitively normal subjects. Brain : a Journal of Neurology. 138: 2701-15. PMID 26220940 DOI: 10.1093/Brain/Awv199  0.543
2015 Hu WT, Watts KD, Shaw LM, Howell JC, Trojanowski JQ, Basra S, Glass JD, Lah JJ, Levey AI. CSF beta-amyloid 1-42 - what are we measuring in Alzheimer's disease? Annals of Clinical and Translational Neurology. 2: 131-9. PMID 25750918 DOI: 10.1002/Acn3.160  0.797
2015 Toledo JB, Zetterberg H, Van Harten AC, Glodzik L, Martinez-Lage P, Bocchio-Chiavetto L, Rami L, Hansson O, Sperling R, Engelborghs S, Osorio RS, Vanderstichele H, Vandijck M, Hampel H, Teipl S, ... ... Hu WT, et al. Alzheimer's disease cerebrospinal fluid biomarker in cognitively normal subjects Brain. 138: 2701-2715. DOI: 10.1093/brain/awv199  0.472
2015 Leung YY, Toledo JB, Nefedov A, Polikar R, Raghavan N, Xie SX, Farnum M, Schultz T, Baek Y, Deerlin VV, Hu WT, Holtzman DM, Fagan AM, Perrin RJ, Grossman M, et al. Identifying amyloid pathology-related cerebrospinal fluid biomarkers for Alzheimer's disease in a multicohort study Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 1: 339-348. DOI: 10.1016/j.dadm.2015.06.008  0.632
2014 Zhang Z, Song M, Liu X, Kang SS, Kwon IS, Duong DM, Seyfried NT, Hu WT, Liu Z, Wang JZ, Cheng L, Sun YE, Yu SP, Levey AI, Ye K. Cleavage of tau by asparagine endopeptidase mediates the neurofibrillary pathology in Alzheimer's disease. Nature Medicine. 20: 1254-62. PMID 25326800 DOI: 10.1038/Nm.3700  0.608
2014 Grossman M, Elman L, McCluskey L, McMillan CT, Boller A, Powers J, Rascovsky K, Hu W, Shaw L, Irwin DJ, Lee VM, Trojanowski JQ. Phosphorylated tau as a candidate biomarker for amyotrophic lateral sclerosis. Jama Neurology. 71: 442-8. PMID 24492862 DOI: 10.1001/Jamaneurol.2013.6064  0.703
2014 Johnston JM, Hu WT, Fardo DW, Greco SJ, Perry G, Montine TJ, Trojanowski JQ, Shaw LM, Ashford JW, Tezapsidis N. Low plasma leptin in cognitively impaired ADNI subjects: gender differences and diagnostic and therapeutic potential. Current Alzheimer Research. 11: 165-74. PMID 24359504 DOI: 10.2174/1567205010666131212114156  0.564
2014 Henriksen K, O'Bryant SE, Hampel H, Trojanowski JQ, Montine TJ, Jeromin A, Blennow K, Lönneborg A, Wyss-Coray T, Soares H, Bazenet C, Sjögren M, Hu W, Lovestone S, Karsdal MA, et al. The future of blood-based biomarkers for Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 10: 115-31. PMID 23850333 DOI: 10.1016/J.Jalz.2013.01.013  0.568
2013 Hu WT, Watts K, Grossman M, Glass J, Lah JJ, Hales C, Shelnutt M, Van Deerlin V, Trojanowski JQ, Levey AI. Reduced CSF p-Tau181 to Tau ratio is a biomarker for FTLD-TDP. Neurology. 81: 1945-52. PMID 24174584 DOI: 10.1212/01.Wnl.0000436625.63650.27  0.688
2013 Hu WT, Shaw LM, Trojanowski JQ. Alzheimer's disease biomarkers: walk with deliberate haste, don't run blithely on? Acta Neuropathologica. 126: 625-9. PMID 24154963 DOI: 10.1007/S00401-013-1197-3  0.521
2013 Yarchoan M, Louneva N, Xie SX, Swenson FJ, Hu W, Soares H, Trojanowski JQ, Lee VM, Kling MA, Shaw LM, Chen-Plotkin A, Wolk DA, Arnold SE. Association of plasma C-reactive protein levels with the diagnosis of Alzheimer's disease. Journal of the Neurological Sciences. 333: 9-12. PMID 23978419 DOI: 10.1016/J.Jns.2013.05.028  0.752
2013 Chalermpalanupap T, Kinkead B, Hu WT, Kummer MP, Hammerschmidt T, Heneka MT, Weinshenker D, Levey AI. Targeting norepinephrine in mild cognitive impairment and Alzheimer's disease. Alzheimer's Research & Therapy. 5: 21. PMID 23634965 DOI: 10.1186/Alzrt175  0.618
2013 Hales CM, Hu WT. From frontotemporal lobar degeneration pathology to frontotemporal lobar degeneration biomarkers. International Review of Psychiatry (Abingdon, England). 25: 210-20. PMID 23611350 DOI: 10.3109/09540261.2013.776522  0.453
2013 Hu WT, Shelnutt M, Wilson A, Yarab N, Kelly C, Grossman M, Libon DJ, Khan J, Lah JJ, Levey AI, Glass J. Behavior matters--cognitive predictors of survival in amyotrophic lateral sclerosis. Plos One. 8: e57584. PMID 23460879 DOI: 10.1371/Journal.Pone.0057584  0.585
2013 Boxer AL, Gold M, Huey E, Hu WT, Rosen H, Kramer J, Gao FB, Burton EA, Chow T, Kao A, Leavitt BR, Lamb B, Grether M, Knopman D, Cairns NJ, et al. The advantages of frontotemporal degeneration drug development (part 2 of frontotemporal degeneration: the next therapeutic frontier). Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 9: 189-98. PMID 23062850 DOI: 10.1016/J.Jalz.2012.03.003  0.513
2013 Leung YY, Toledo J, Nefedov A, Polikar R, Raghavan N, Xie S, Farnum M, Schultz T, Baek Y, Lobanov V, DiBernardo A, Deerlin VV, Kling M, Chen-Plotkin A, Mailman M, ... Hu W, et al. Identifying multi-analyte CSF biomarkers for Alzheimer’s disease in a multi-cohort study Alzheimers & Dementia. 9. DOI: 10.1016/J.Jalz.2013.04.059  0.756
2012 Hu WT, Holtzman DM, Fagan AM, Shaw LM, Perrin R, Arnold SE, Grossman M, Xiong C, Craig-Schapiro R, Clark CM, Pickering E, Kuhn M, Chen Y, Van Deerlin VM, McCluskey L, et al. Plasma multianalyte profiling in mild cognitive impairment and Alzheimer disease. Neurology. 79: 897-905. PMID 22855860 DOI: 10.1212/Wnl.0B013E318266Fa70  0.801
2012 Arnold SE, Xie SX, Leung YY, Wang LS, Kling MA, Han X, Kim EJ, Wolk DA, Bennett DA, Chen-Plotkin A, Grossman M, Hu W, Lee VM, Mackin RS, Trojanowski JQ, et al. Plasma biomarkers of depressive symptoms in older adults. Translational Psychiatry. 2: e65. PMID 22832727 DOI: 10.1038/Tp.2011.63  0.716
2012 Toledo JB, Brettschneider J, Grossman M, Arnold SE, Hu WT, Xie SX, Lee VM, Shaw LM, Trojanowski JQ. CSF biomarkers cutoffs: the importance of coincident neuropathological diseases. Acta Neuropathologica. 124: 23-35. PMID 22526019 DOI: 10.1007/S00401-012-0983-7  0.738
2012 Hu W, Basra S, Watts K, Glass J, Lah J, Levey A. Cerebrospinal Fluid beta-Amyloid 1-42 Solubility Is Influenced by Apolipoproteins E and J (S14.002) Neurology. 78: S14.002-S14.002. DOI: 10.1212/Wnl.78.1_Meetingabstracts.S14.002  0.482
2012 Toledo J, Brettschneider J, Grossman M, Arnold S, Hu W, Xie S, Lee V, Shaw L, Trojanowski J. Improving Diagnostic Accuracy for Dementia: CSF Biomarker Cutoffs Based on Clinical and Neuropathological Criteria (IN3-1.010) Neurology. 78: IN3-1.010-IN3-1.010. DOI: 10.1212/Wnl.78.1_Meetingabstracts.In3-1.010  0.608
2012 Leung YY, Wang L, Hu WT, Kling M, Wolk D, Trojanowski J, Lee V, Shaw L, Arnold S. P2-049: Cerebrospinal fluid biochemical biomarkers of depressive symptoms in older adults Alzheimer's & Dementia. 8: P280-P280. DOI: 10.1016/J.Jalz.2012.05.2143  0.525
2011 Hu WT, Trojanowski JQ, Shaw LM. Biomarkers in frontotemporal lobar degenerations--progress and challenges. Progress in Neurobiology. 95: 636-48. PMID 21554923 DOI: 10.1016/J.Pneurobio.2011.04.012  0.523
2011 Chen-Plotkin AS, Hu WT, Siderowf A, Weintraub D, Goldmann Gross R, Hurtig HI, Xie SX, Arnold SE, Grossman M, Clark CM, Shaw LM, McCluskey L, Elman L, Van Deerlin VM, Lee VM, et al. Plasma epidermal growth factor levels predict cognitive decline in Parkinson disease. Annals of Neurology. 69: 655-63. PMID 21520231 DOI: 10.1002/Ana.22271  0.724
2011 Chen-Plotkin AS, Martinez-Lage M, Sleiman PM, Hu W, Greene R, Wood EM, Bing S, Grossman M, Schellenberg GD, Hatanpaa KJ, Weiner MF, White CL, Brooks WS, Halliday GM, Kril JJ, et al. Genetic and clinical features of progranulin-associated frontotemporal lobar degeneration. Archives of Neurology. 68: 488-97. PMID 21482928 DOI: 10.1001/Archneurol.2011.53  0.753
2011 Vass R, Ashbridge E, Geser F, Hu WT, Grossman M, Clay-Falcone D, Elman L, McCluskey L, Lee VM, Van Deerlin VM, Trojanowski JQ, Chen-Plotkin AS. Risk genotypes at TMEM106B are associated with cognitive impairment in amyotrophic lateral sclerosis. Acta Neuropathologica. 121: 373-80. PMID 21104415 DOI: 10.1007/S00401-010-0782-Y  0.715
2011 Soares H, Potter W, Immermann F, Pickering E, Kuhn M, Shera D, Zagouras P, Swenson F, Wan H, Ferm M, Siuciak J, Koroshetz W, Simon A, Lee V, Buckholtz N, ... Hu W, et al. Changes in plasma based biomarkers in Alzheimer's disease, mild cognitively impaired and aged matched normal controls from the ADNI cohort Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.960  0.639
2011 Arnold S, Xie SX, Leung Y, Kim E, Kling M, Wilson R, Bennett D, Hu W, Mackin S, Grossman M, Chen-Plotkin A, Wolk D, Lee V, Trojanowski J, Shaw L. P2-017: Biochemical Biomarkers of Depressive Symptoms in ADNI Alzheimer's & Dementia. 7: S312-S312. DOI: 10.1016/J.Jalz.2011.05.907  0.691
2011 Hu WT, Holtzman D, Clark C, Grossman M, Karlawish J, Fagan A, Lee V, Swenson F, Craig-Schapiro R, Perrin RJ, Soares H, Trojanowski J, Xiong C, Morris J, Shaw L, et al. P1-089: Plasma multianalyte profiling of mild cognitive impairment and Alzheimer's disease in two academic centers and the Alzheimer's Disease Neuroimaging Initiative Alzheimer's & Dementia. 7: S138-S138. DOI: 10.1016/J.Jalz.2011.05.368  0.781
2010 Hu WT, Chen-Plotkin A, Grossman M, Arnold SE, Clark CM, Shaw LM, McCluskey L, Elman L, Hurtig HI, Siderowf A, Lee VM, Soares H, Trojanowski JQ. Novel CSF biomarkers for frontotemporal lobar degenerations. Neurology. 75: 2079-86. PMID 21048198 DOI: 10.1016/J.Jalz.2010.05.253  0.771
2010 Hu WT, Wang Z, Lee VM, Trojanowski JQ, Detre JA, Grossman M. Distinct cerebral perfusion patterns in FTLD and AD. Neurology. 75: 881-8. PMID 20819999 DOI: 10.1212/Wnl.0B013E3181F11E35  0.663
2010 Hu WT, McMillan C, Libon D, Leight S, Forman M, Lee VM, Trojanowski JQ, Grossman M. Multimodal predictors for Alzheimer disease in nonfluent primary progressive aphasia. Neurology. 75: 595-602. PMID 20713948 DOI: 10.1212/Wnl.0B013E3181Ed9C52  0.823
2010 Hu WT, Chen-Plotkin A, Arnold SE, Grossman M, Clark CM, Shaw LM, McCluskey L, Elman L, Karlawish J, Hurtig HI, Siderowf A, Lee VM, Soares H, Trojanowski JQ. Biomarker discovery for Alzheimer's disease, frontotemporal lobar degeneration, and Parkinson's disease. Acta Neuropathologica. 120: 385-99. PMID 20652578 DOI: 10.1007/S00401-010-0723-9  0.808
2010 Josephs KA, Whitwell JL, Boeve BF, Knopman DS, Petersen RC, Hu WT, Parisi JE, Dickson DW, Jack CR. Anatomical differences between CBS-corticobasal degeneration and CBS-Alzheimer's disease. Movement Disorders : Official Journal of the Movement Disorder Society. 25: 1246-52. PMID 20629131 DOI: 10.1002/Mds.23062  0.646
2010 Hu WT, Chen-Plotkin A, Arnold SE, Grossman M, Clark CM, Shaw LM, Pickering E, Kuhn M, Chen Y, McCluskey L, Elman L, Karlawish J, Hurtig HI, Siderowf A, Lee VM, et al. Novel CSF biomarkers for Alzheimer's disease and mild cognitive impairment. Acta Neuropathologica. 119: 669-78. PMID 20232070 DOI: 10.1007/S00401-010-0667-0  0.798
2010 Hu WT, Grossman M, Chen-Plotkin A, Arnold SE, Clark CM, Shaw LM, Lee VM, Soares HD, Trojanowski JQ. O1-07-05: Novel CSF biomarkers for frontotemporal lobar degenerations Alzheimer's & Dementia. 6: S84-S84. DOI: 10.1016/j.jalz.2010.05.253  0.661
2010 Soares H, Hu W, Grossman M, Clark C, Pickering E, Chen Y, Kuhn M, Chen-Plotkin A, Arnold S, Shaw L, Lee VM, Swenson F, Trojanowski JQ. P2-093: Multiplex plasma panels as screening tools in Alzheimer's disease. Alzheimer's & Dementia. 6: S340-S340. DOI: 10.1016/J.Jalz.2010.05.1139  0.718
2009 Hu WT, Seelaar H, Josephs KA, Knopman DS, Boeve BF, Sorenson EJ, McCluskey L, Elman L, Schelhaas HJ, Parisi JE, Kuesters B, Lee VM, Trojanowski JQ, Petersen RC, van Swieten JC, et al. Survival profiles of patients with frontotemporal dementia and motor neuron disease. Archives of Neurology. 66: 1359-64. PMID 19901167 DOI: 10.1001/Archneurol.2009.253  0.751
2009 Hu WT, Grossman M. TDP-43 and frontotemporal dementia. Current Neurology and Neuroscience Reports. 9: 353-8. PMID 19664364 DOI: 10.1007/S11910-009-0052-3  0.568
2009 Hu WT, Rippon GW, Boeve BF, Knopman DS, Petersen RC, Parisi JE, Josephs KA. Alzheimer's disease and corticobasal degeneration presenting as corticobasal syndrome. Movement Disorders : Official Journal of the Movement Disorder Society. 24: 1375-9. PMID 19425061 DOI: 10.1002/Mds.22574  0.683
2008 Hu WT, Josephs KA, Knopman DS, Boeve BF, Dickson DW, Petersen RC, Parisi JE. Temporal lobar predominance of TDP-43 neuronal cytoplasmic inclusions in Alzheimer disease. Acta Neuropathologica. 116: 215-20. PMID 18592255 DOI: 10.1007/S00401-008-0400-4  0.647
2008 Josephs KA, Whitwell JL, Knopman DS, Hu WT, Stroh DA, Baker M, Rademakers R, Boeve BF, Parisi JE, Smith GE, Ivnik RJ, Petersen RC, Jack CR, Dickson DW. Abnormal TDP-43 immunoreactivity in AD modifies clinicopathologic and radiologic phenotype. Neurology. 70: 1850-7. PMID 18401022 DOI: 10.1212/01.Wnl.0000304041.09418.B1  0.673
2008 Josephs KA, Whitwell JL, Duffy JR, Vanvoorst WA, Strand EA, Hu WT, Boeve BF, Graff-Radford NR, Parisi JE, Knopman DS, Dickson DW, Jack CR, Petersen RC. Progressive aphasia secondary to Alzheimer disease vs FTLD pathology. Neurology. 70: 25-34. PMID 18166704 DOI: 10.1212/01.Wnl.0000287073.12737.35  0.684
2008 Hu WT, Rippon GA, Boeve BF, Parisi JE, Knopman DS, Petersen RC, Josephs KA. P3-018: Alzheimer's disease presenting as corticobasal syndrome Alzheimer's & Dementia. 4: T521-T522. DOI: 10.1016/J.Jalz.2008.05.1581  0.652
2007 Hu WT, Parisi JE, Knopman DS, Boeve BF, Dickson DW, Ahlskog JE, Petersen RC, Josephs KA. Clinical features and survival of 3R and 4R tauopathies presenting as behavioral variant frontotemporal dementia. Alzheimer Disease and Associated Disorders. 21: S39-43. PMID 18090422 DOI: 10.1097/Wad.0B013E31815Bf5E5  0.574
2007 Hu WT, Mandrekar JN, Parisi JE, Knopman DS, Boeve BF, Petersen RC, Hutton M, Dickson DW, Josephs KA. Clinical features of pathologic subtypes of behavioral--variant frontotemporal dementia. Archives of Neurology. 64: 1611-6. PMID 17998443 DOI: 10.1001/Archneur.64.11.1611  0.635
2007 Hu WT, Josephs KA, Dickson DW, Knopman DS, Boeve BF, Petersen RC, Parisi JE. Dual pathologies: utility of TAR DNA-binding protein 43 (TDP-43) staining in patients with frontal and temporal lobe abnormalities and Alzheimer disease Journal of Neuropathology and Experimental Neurology. 66: 421. DOI: 10.1096/Fasebj.21.5.A21-A  0.631
2007 Hu WT, Josephs KA, Dickson DW, Knopman DS, Boeve BF, Petersen RC, Parisi JE. Dual pathologies: Utility of TAR DNA‐binding Protein 43 (TDP‐43) Staining in Patients with Frontal and Temporal Lobe Abnormalities and Alzheimer disease The Faseb Journal. 21. DOI: 10.1096/FASEBJ.21.5.A21-A  0.618
2006 Hu WT, Murray JA, Greenaway MC, Parisi JE, Josephs KA. Cognitive impairment and celiac disease. Archives of Neurology. 63: 1440-6. PMID 17030661 DOI: 10.1001/Archneur.63.10.1440  0.627
2006 Misiura M, Hu WT, Turner J, Howell JC. IC-P-039: RACE MODIFIES FUNCTIONAL CONNECTIVITY OF THE DEFAULT MODE NETWORK IN AGING AND ALZHEIMER'S DISEASE Alzheimer's & Dementia. 14: P40-P41. DOI: 10.1016/J.Jalz.2018.06.2103  0.708
2006 Misiura M, Hu WT, Turner J, Howell JC. P1-008: RACE MODIFIES FUNCTIONAL CONNECTIVITY OF THE DEFAULT MODE NETWORK IN AGING AND ALZHEIMER'S DISEASE Alzheimer's & Dementia. 14: P265-P265. DOI: 10.1016/j.jalz.2018.06.009  0.697
2005 Hu WT, Josephs KA, Ahlskog JE, Shin C, Boeve BF, Witte RJ. MRI correlates of alien leg-like phenomenon in corticobasal degeneration. Movement Disorders : Official Journal of the Movement Disorder Society. 20: 870-3. PMID 15799014 DOI: 10.1002/Mds.20451  0.449
2005 Hu WT, Petersen RC. [P-071]: Use of angiotensin converting enzyme inhibitors and age of Alzheimer's disease onset in patients with the Apolipoprotein E ϵ4 allele Alzheimer's & Dementia. 1: S30-S30. DOI: 10.1016/J.Jalz.2005.06.145  0.374
2003 Hu W, Gray NW, Brimijoin S. Amyloid-beta increases acetylcholinesterase expression in neuroblastoma cells by reducing enzyme degradation. Journal of Neurochemistry. 86: 470-8. PMID 12871588 DOI: 10.1046/J.1471-4159.2003.01855.X  0.357
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