| Year |
Citation |
Score |
| 2024 |
Thosar SA, Barnes RP, Detwiler A, Bhargava R, Wondisford A, O'Sullivan RJ, Opresko PL. Oxidative guanine base damage plays a dual role in regulating productive ALT-associated homology-directed repair. Cell Reports. 43: 113656. PMID 38194346 DOI: 10.1016/j.celrep.2023.113656 |
0.46 |
|
| 2023 |
Johnson SA, Paul T, Sanford SL, Schnable BL, Detwiler AC, Thosar SA, Van Houten B, Myong S, Opresko PL. BG4 antibody can recognize telomeric G-quadruplexes harboring destabilizing base modifications and lesions. Nucleic Acids Research. PMID 38153143 DOI: 10.1093/nar/gkad1209 |
0.315 |
|
| 2023 |
Rosa M, Barnes RP, Nyalapatla PR, Wipf P, Opresko PL. OGG1 and MUTYH repair activities promote telomeric 8-oxoguanine induced cellular senescence. Biorxiv : the Preprint Server For Biology. PMID 37090589 DOI: 10.1101/2023.04.10.536247 |
0.356 |
|
| 2023 |
Liu M, Pan H, Kaur P, Wang LJ, Jin M, Detwiler AC, Opresko PL, Tao YJ, Wang H, Riehn R. Assembly Path Dependence of Telomeric DNA Compaction by TRF1, TIN2, and SA1. Biophysical Journal. PMID 37081787 DOI: 10.1016/j.bpj.2023.04.014 |
0.512 |
|
| 2023 |
Barnes RP, Thosar SA, Opresko PL. Telomere Fragility and MiDAS: Managing the Gaps at the End of the Road. Genes. 14. PMID 36833275 DOI: 10.3390/genes14020348 |
0.486 |
|
| 2022 |
Yu T, Slone J, Liu W, Barnes R, Opresko PL, Wark L, Mai S, Horvath S, Huang T. Premature aging is associated with higher levels of 8-oxoguanine and increased DNA damage in the Polg mutator mouse. Aging Cell. e13669. PMID 35993394 DOI: 10.1111/acel.13669 |
0.36 |
|
| 2022 |
Barnes RP, de Rosa M, Thosar SA, Detwiler AC, Roginskaya V, Van Houten B, Bruchez MP, Stewart-Ornstein J, Opresko PL. Telomeric 8-oxo-guanine drives rapid premature senescence in the absence of telomere shortening. Nature Structural & Molecular Biology. PMID 35773409 DOI: 10.1038/s41594-022-00790-y |
0.404 |
|
| 2022 |
Paul T, Opresko PL, Ha T, Myong S. Vectorial folding of telomere overhang promotes higher accessibility. Nucleic Acids Research. PMID 35687089 DOI: 10.1093/nar/gkac401 |
0.342 |
|
| 2022 |
Kumar N, Theil AF, Roginskaya V, Ali Y, Calderon M, Watkins SC, Barnes RP, Opresko PL, Pines A, Lans H, Vermeulen W, Van Houten B. Global and transcription-coupled repair of 8-oxoG is initiated by nucleotide excision repair proteins. Nature Communications. 13: 974. PMID 35190564 DOI: 10.1038/s41467-022-28642-9 |
0.311 |
|
| 2021 |
Kaur P, Barnes R, Pan H, Detwiler AC, Liu M, Mahn C, Hall J, Messenger Z, You C, Piehler J, Smart RC, Riehn R, Opresko PL, Wang H. TIN2 is an architectural protein that facilitates TRF2-mediated trans- and cis-interactions on telomeric DNA. Nucleic Acids Research. PMID 34883513 DOI: 10.1093/nar/gkab1142 |
0.513 |
|
| 2021 |
De Rosa M, Johnson SA, Opresko PL. Roles for the 8-Oxoguanine DNA Repair System in Protecting Telomeres From Oxidative Stress. Frontiers in Cell and Developmental Biology. 9: 758402. PMID 34869348 DOI: 10.3389/fcell.2021.758402 |
0.389 |
|
| 2021 |
Pan H, Kaur P, Barnes R, Detwiler AC, Sanford SL, Liu M, Xu P, Mahn C, Tang Q, Hao P, Bhattaram D, You C, Gu X, Lu W, Piehler J, ... ... Opresko PL, et al. Structure, dynamics, and regulation of TRF1-TIN2-mediated trans- and cis-interactions on telomeric DNA. The Journal of Biological Chemistry. 101080. PMID 34403696 DOI: 10.1016/j.jbc.2021.101080 |
0.524 |
|
| 2021 |
Sanford SL, Welfer GA, Freudenthal BD, Opresko PL. How DNA damage and non-canonical nucleotides alter the telomerase catalytic cycle. Dna Repair. 107: 103198. PMID 34371388 DOI: 10.1016/j.dnarep.2021.103198 |
0.412 |
|
| 2020 |
Zhu RY, Majumdar C, Khuu C, De Rosa M, Opresko PL, David SS, Kool ET. Designer Fluorescent Adenines Enable Real-Time Monitoring of MUTYH Activity. Acs Central Science. 6: 1735-1742. PMID 33145410 DOI: 10.1021/Acscentsci.0C00369 |
0.446 |
|
| 2020 |
Lee HT, Sanford S, Paul T, Choi J, Bose A, Opresko PL, Myong S. Position-Dependent Effect of Guanine Base Damage and Mutations on Telomeric G-quadruplex and Telomerase Extension. Biochemistry. PMID 32578995 DOI: 10.1021/Acs.Biochem.0C00434 |
0.44 |
|
| 2020 |
Schaich MA, Sanford SL, Welfer GA, Johnson SA, Khoang TH, Opresko PL, Freudenthal BD. Mechanisms of nucleotide selection by telomerase. Elife. 9. PMID 32501800 DOI: 10.7554/Elife.55438 |
0.44 |
|
| 2019 |
Qian W, Kumar N, Roginskaya V, Fouquerel E, Opresko PL, Shiva S, Watkins SC, Kolodieznyi D, Bruchez MP, Van Houten B. Chemoptogenetic damage to mitochondria causes rapid telomere dysfunction. Proceedings of the National Academy of Sciences of the United States of America. PMID 31451640 DOI: 10.1073/Pnas.1910574116 |
0.399 |
|
| 2019 |
Jang S, Kumar N, Beckwitt EC, Kong M, Fouquerel E, Rapić-Otrin V, Prasad R, Watkins SC, Khuu C, Majumdar C, David SS, Wilson SH, Bruchez MP, Opresko PL, Van Houten B. Damage sensor role of UV-DDB during base excision repair. Nature Structural & Molecular Biology. PMID 31332353 DOI: 10.1038/S41594-019-0261-7 |
0.443 |
|
| 2019 |
Fouquerel E, Barnes RP, Wang H, Opresko PL. Measuring UV Photoproduct Repair in Isolated Telomeres and Bulk Genomic DNA. Methods in Molecular Biology (Clifton, N.J.). 1999: 295-306. PMID 31127586 DOI: 10.1007/978-1-4939-9500-4_20 |
0.475 |
|
| 2019 |
Luu HN, Qi M, Wang R, Adams-Haduch J, Miljkovic I, Opresko PL, Jin A, Koh WP, Yuan JM. Association Between Leukocyte Telomere Length and Colorectal Cancer Risk in the Singapore Chinese Health Study. Clinical and Translational Gastroenterology. 10: 1-9. PMID 31117113 DOI: 10.14309/Ctg.0000000000000043 |
0.321 |
|
| 2019 |
Fouquerel E, Barnes RP, Uttam S, Watkins SC, Bruchez MP, Opresko PL. Targeted and Persistent 8-Oxoguanine Base Damage at Telomeres Promotes Telomere Loss and Crisis. Molecular Cell. PMID 31101499 DOI: 10.1016/J.Molcel.2019.04.024 |
0.364 |
|
| 2019 |
Kaur P, Barnes R, Pan H, Opresko P, Riehn R, Wang H. Single-Molecule Study of TRF2 Mediated DNA Compaction using Physiologically Relevant Long Telomeric DNA Biophysical Journal. 116: 505a. DOI: 10.1016/J.Bpj.2018.11.2725 |
0.546 |
|
| 2019 |
Lee H, Paul T, Choe J, Sanford S, Opresko PL, Myong S. DNA Base Damage and Consequential Point Mutation Controls Telomere Conformation and Elaborates Telomerase Extension Activity Biophysical Journal. 116: 39a. DOI: 10.1016/J.Bpj.2018.11.256 |
0.497 |
|
| 2019 |
Pan H, Dangi S, Kaur P, Hao P, Weninger K, Riehn R, Opresko P, Wang H. TIN2 is an Architectural Protein Stabilizing TRF1 at Telomere Biophysical Journal. 116: 211a-212a. DOI: 10.1016/J.Bpj.2018.11.1168 |
0.339 |
|
| 2018 |
Robinson AR, Yousefzadeh MJ, Rozgaja TA, Wang J, Li X, Tilstra JS, Feldman CH, Gregg SQ, Johnson CH, Skoda EM, Frantz MC, Bell-Temin H, Pope-Varsalona H, Gurkar AU, Nasto LA, ... ... Opresko PL, et al. Spontaneous DNA damage to the nuclear genome promotes senescence, redox imbalance and aging. Redox Biology. 17: 259-273. PMID 29747066 DOI: 10.1016/J.Redox.2018.04.007 |
0.409 |
|
| 2018 |
Barnes RP, Fouquerel E, Opresko PL. The impact of oxidative DNA damage and stress on telomere homeostasis. Mechanisms of Ageing and Development. PMID 29604323 DOI: 10.1016/j.mad.2018.03.013 |
0.336 |
|
| 2018 |
Yuan JM, Beckman KB, Wang R, Bull C, Adams-Haduch J, Huang JY, Jin A, Opresko P, Newman AB, Zheng YL, Fenech M, Koh WP. Leukocyte telomere length in relation to risk of lung adenocarcinoma incidence: Findings from the Singapore Chinese Health Study. International Journal of Cancer. PMID 29318605 DOI: 10.1002/Ijc.31251 |
0.318 |
|
| 2018 |
Opresko P. Investigating How Oxidative DNA Base Damage Alters Telomere Maintenance Free Radical Biology and Medicine. 128: S11. DOI: 10.1016/J.Freeradbiomed.2018.10.387 |
0.537 |
|
| 2017 |
Orenstein A, Berlyoung AS, Rastede EE, Pham HH, Fouquerel E, Murphy CT, Leibowitz BJ, Yu J, Srivastava T, Armitage BA, Opresko PL. γPNA FRET Pair Miniprobes for Quantitative Fluorescent In Situ Hybridization to Telomeric DNA in Cells and Tissue. Molecules (Basel, Switzerland). 22. PMID 29207465 DOI: 10.3390/Molecules22122117 |
0.355 |
|
| 2017 |
Lee HT, Bose A, Lee CY, Opresko PL, Myong S. Molecular mechanisms by which oxidative DNA damage promotes telomerase activity. Nucleic Acids Research. PMID 28981887 DOI: 10.1093/Nar/Gkx789 |
0.585 |
|
| 2017 |
Zhou J, Chan J, Lambelé M, Yusufzai T, Stumpff J, Opresko PL, Thali M, Wallace SS. NEIL3 Repairs Telomere Damage during S Phase to Secure Chromosome Segregation at Mitosis. Cell Reports. 20: 2044-2056. PMID 28854357 DOI: 10.1016/J.Celrep.2017.08.020 |
0.542 |
|
| 2017 |
Jenkins FJ, Kerr CM, Fouquerel E, Bovbjerg DH, Opresko PL. Modified Terminal Restriction Fragment Analysis for Quantifying Telomere Length Using In-gel Hybridization. Journal of Visualized Experiments : Jove. PMID 28715381 DOI: 10.3791/56001 |
0.532 |
|
| 2016 |
Fouquerel E, Opresko P. Convergence of The Nobel Fields of Telomere Biology and DNA Repair. Photochemistry and Photobiology. PMID 27861975 DOI: 10.1111/Php.12672 |
0.543 |
|
| 2016 |
Garcia-Exposito L, Bournique E, Bergoglio V, Bose A, Barroso-Gonzalez J, Zhang S, Roncaioli JL, Lee M, Wallace CT, Watkins SC, Opresko PL, Hoffmann JS, O'Sullivan RJ. Proteomic Profiling Reveals a Specific Role for Translesion DNA Polymerase η in the Alternative Lengthening of Telomeres. Cell Reports. 17: 1858-1871. PMID 27829156 DOI: 10.1016/J.Celrep.2016.10.048 |
0.604 |
|
| 2016 |
Fouquerel E, Lormand J, Bose A, Lee HT, Kim GS, Li J, Sobol RW, Freudenthal BD, Myong S, Opresko PL. Oxidative guanine base damage regulates human telomerase activity. Nature Structural & Molecular Biology. PMID 27820808 DOI: 10.1038/Nsmb.3319 |
0.496 |
|
| 2016 |
Tippana R, Hwang H, Opresko PL, Bohr VA, Myong S. Single-molecule imaging reveals a common mechanism shared by G-quadruplex-resolving helicases. Proceedings of the National Academy of Sciences of the United States of America. PMID 27407146 DOI: 10.1073/Pnas.1603724113 |
0.503 |
|
| 2016 |
Lin J, Countryman P, Chen H, Pan H, Fan Y, Jiang Y, Kaur P, Miao W, Gurgel G, You C, Piehler J, Kad NM, Riehn R, Opresko PL, Smith S, et al. Functional interplay between SA1 and TRF1 in telomeric DNA binding and DNA-DNA pairing. Nucleic Acids Research. PMID 27298259 DOI: 10.1093/Nar/Gkw518 |
0.577 |
|
| 2016 |
Fouquerel E, Parikh D, Opresko P. DNA damage processing at telomeres: The ends justify the means. Dna Repair. 44: 159-168. PMID 27233113 DOI: 10.1016/J.Dnarep.2016.05.022 |
0.598 |
|
| 2016 |
Opresko PL, Shay JW. Telomere-Associated Aging Disorders. Ageing Research Reviews. PMID 27215853 DOI: 10.1016/J.Arr.2016.05.009 |
0.446 |
|
| 2016 |
Kaur P, Wu D, Lin J, Countryman P, Bradford KC, Erie DA, Riehn R, Opresko PL, Wang H. Enhanced electrostatic force microscopy reveals higher-order DNA looping mediated by the telomeric protein TRF2. Scientific Reports. 6: 20513. PMID 26856421 DOI: 10.1038/Srep20513 |
0.563 |
|
| 2016 |
Lee H, Kim G, Opresko P, Myong S. Single Molecule Studies of Oxidative Damage on Human Telomere Biophysical Journal. 110: 406a. DOI: 10.1016/J.Bpj.2015.11.2191 |
0.488 |
|
| 2015 |
Parikh D, Fouquerel E, Murphy CT, Wang H, Opresko PL. Telomeres are partly shielded from ultraviolet-induced damage and proficient for nucleotide excision repair of photoproducts. Nature Communications. 6: 8214. PMID 26351258 DOI: 10.1038/Ncomms9214 |
0.504 |
|
| 2015 |
Wang H, Lin J, Kaur P, Countryman P, Opresko P, Smith S, Tao J. Revealing Structure and Dynamics of Telomere Maintenance Proteins on DNA: One Molecule at a Time Biophysical Journal. 108: 7a. DOI: 10.1016/J.Bpj.2014.11.059 |
0.57 |
|
| 2014 |
Pope-Varsalona H, Liu FJ, Guzik L, Opresko PL. Polymerase η suppresses telomere defects induced by DNA damaging agents. Nucleic Acids Research. 42: 13096-109. PMID 25355508 DOI: 10.1093/Nar/Gku1030 |
0.548 |
|
| 2014 |
Hwang H, Opresko P, Myong S. Single-molecule real-time detection of telomerase extension activity. Scientific Reports. 4: 6391. PMID 25263700 DOI: 10.1038/Srep06391 |
0.454 |
|
| 2014 |
Pham HH, Murphy CT, Sureshkumar G, Ly DH, Opresko PL, Armitage BA. Cooperative hybridization of γPNA miniprobes to a repeating sequence motif and application to telomere analysis. Organic & Biomolecular Chemistry. 12: 7345-54. PMID 25115693 DOI: 10.1039/C4Ob00953C |
0.445 |
|
| 2014 |
Murphy CT, Gupta A, Armitage BA, Opresko PL. Hybridization of G-quadruplex-forming peptide nucleic acids to guanine-rich DNA templates inhibits DNA polymerase η extension. Biochemistry. 53: 5315-22. PMID 25068499 DOI: 10.1021/Bi5006859 |
0.549 |
|
| 2014 |
Hwang H, Kreig A, Calvert J, Lormand J, Kwon Y, Daley JM, Sung P, Opresko PL, Myong S. Telomeric overhang length determines structural dynamics and accessibility to telomerase and ALT-associated proteins. Structure (London, England : 1993). 22: 842-53. PMID 24836024 DOI: 10.1016/J.Str.2014.03.013 |
0.469 |
|
| 2014 |
Croteau DL, Popuri V, Opresko PL, Bohr VA. Human RecQ helicases in DNA repair, recombination, and replication. Annual Review of Biochemistry. 83: 519-52. PMID 24606147 DOI: 10.1146/Annurev-Biochem-060713-035428 |
0.439 |
|
| 2014 |
Lin J, Kaur P, Countryman P, Opresko PL, Wang H. Unraveling secrets of telomeres: one molecule at a time. Dna Repair. 20: 142-53. PMID 24569170 DOI: 10.1016/J.Dnarep.2014.01.012 |
0.425 |
|
| 2014 |
Lin J, Countryman P, Buncher N, Kaur P, E L, Zhang Y, Gibson G, You C, Watkins SC, Piehler J, Opresko PL, Kad NM, Wang H. TRF1 and TRF2 use different mechanisms to find telomeric DNA but share a novel mechanism to search for protein partners at telomeres. Nucleic Acids Research. 42: 2493-504. PMID 24271387 DOI: 10.1093/Nar/Gkt1132 |
0.534 |
|
| 2013 |
Lormand JD, Buncher N, Murphy CT, Kaur P, Lee MY, Burgers P, Wang H, Kunkel TA, Opresko PL. DNA polymerase δ stalls on telomeric lagging strand templates independently from G-quadruplex formation. Nucleic Acids Research. 41: 10323-33. PMID 24038470 DOI: 10.1093/Nar/Gkt813 |
0.474 |
|
| 2012 |
Hwang H, Buncher N, Opresko PL, Myong S. POT1-TPP1 regulates telomeric overhang structural dynamics. Structure (London, England : 1993). 20: 1872-80. PMID 22981946 DOI: 10.1016/J.Str.2012.08.018 |
0.526 |
|
| 2012 |
Damerla RR, Knickelbein KE, Strutt S, Liu FJ, Wang H, Opresko PL. Werner syndrome protein suppresses the formation of large deletions during the replication of human telomeric sequences. Cell Cycle (Georgetown, Tex.). 11: 3036-44. PMID 22871734 DOI: 10.4161/Cc.21399 |
0.507 |
|
| 2012 |
Miller AS, Balakrishnan L, Buncher NA, Opresko PL, Bambara RA. Telomere proteins POT1, TRF1 and TRF2 augment long-patch base excision repair in vitro. Cell Cycle (Georgetown, Tex.). 11: 998-1007. PMID 22336916 DOI: 10.4161/Cc.11.5.19483 |
0.559 |
|
| 2012 |
Hwang H, Buncher N, Opresko P, Myong S. The Dynamic Interplay Between Telomere-Binding Proteins POT1 and TPP1 in G-Quadruplex DNA Biophysical Journal. 102: 15a. DOI: 10.1016/J.Bpj.2011.11.107 |
0.608 |
|
| 2011 |
Choi S, Wang W, Ribeiro AJ, Kalinowski A, Gregg SQ, Opresko PL, Niedernhofer LJ, Rohde GK, Dahl KN. Computational image analysis of nuclear morphology associated with various nuclear-specific aging disorders. Nucleus (Austin, Tex.). 2: 570-9. PMID 22127259 DOI: 10.4161/Nucl.2.6.17798 |
0.347 |
|
| 2011 |
O'Donovan A, Pantell MS, Puterman E, Dhabhar FS, Blackburn EH, Yaffe K, Cawthon RM, Opresko PL, Hsueh WC, Satterfield S, Newman AB, Ayonayon HN, Rubin SM, Harris TB, Epel ES, et al. Cumulative inflammatory load is associated with short leukocyte telomere length in the Health, Aging and Body Composition Study. Plos One. 6: e19687. PMID 21602933 DOI: 10.1371/Journal.Pone.0019687 |
0.315 |
|
| 2011 |
Wang H, Nora GJ, Ghodke H, Opresko PL. Single molecule studies of physiologically relevant telomeric tails reveal POT1 mechanism for promoting G-quadruplex unfolding. The Journal of Biological Chemistry. 286: 7479-89. PMID 21183684 DOI: 10.1074/Jbc.M110.205641 |
0.575 |
|
| 2010 |
Damerla RR, Knickelbein KE, Kepchia D, Jackson A, Armitage BA, Eckert KA, Opresko PL. Telomeric repeat mutagenicity in human somatic cells is modulated by repeat orientation and G-quadruplex stability. Dna Repair. 9: 1119-29. PMID 20800555 DOI: 10.1016/J.Dnarep.2010.07.014 |
0.673 |
|
| 2010 |
Liu FJ, Barchowsky A, Opresko PL. The Werner syndrome protein suppresses telomeric instability caused by chromium (VI) induced DNA replication stress. Plos One. 5: e11152. PMID 20585393 DOI: 10.1371/Journal.Pone.0011152 |
0.482 |
|
| 2010 |
Kusumoto-Matsuo R, Opresko PL, Ramsden D, Tahara H, Bohr VA. Cooperation of DNA-PKcs and WRN helicase in the maintenance of telomeric D-loops. Aging. 2: 274-84. PMID 20519774 DOI: v2/n5/full/100141.html |
0.542 |
|
| 2010 |
Nora GJ, Buncher NA, Opresko PL. Telomeric protein TRF2 protects Holliday junctions with telomeric arms from displacement by the Werner syndrome helicase. Nucleic Acids Research. 38: 3984-98. PMID 20215438 DOI: 10.1093/Nar/Gkq144 |
0.482 |
|
| 2010 |
Shah SN, Opresko PL, Meng X, Lee MY, Eckert KA. DNA structure and the Werner protein modulate human DNA polymerase delta-dependent replication dynamics within the common fragile site FRA16D. Nucleic Acids Research. 38: 1149-62. PMID 19969545 DOI: 10.1093/Nar/Gkp1131 |
0.754 |
|
| 2009 |
Sowd G, Wang H, Pretto D, Chazin WJ, Opresko PL. Replication protein A stimulates the Werner syndrome protein branch migration activity. The Journal of Biological Chemistry. 284: 34682-91. PMID 19812417 DOI: 10.1074/Jbc.M109.049031 |
0.558 |
|
| 2009 |
Liu FJ, Barchowsky A, Opresko PL. The Werner syndrome protein functions in repair of Cr(VI)-induced replication-associated DNA damage. Toxicological Sciences : An Official Journal of the Society of Toxicology. 110: 307-18. PMID 19487340 DOI: 10.1093/Toxsci/Kfp104 |
0.527 |
|
| 2009 |
Opresko PL, Sowd G, Wang H. The Werner syndrome helicase/exonuclease processes mobile D-loops through branch migration and degradation. Plos One. 4: e4825. PMID 19283071 DOI: 10.1371/Journal.Pone.0004825 |
0.491 |
|
| 2008 |
Sowd G, Lei M, Opresko PL. Mechanism and substrate specificity of telomeric protein POT1 stimulation of the Werner syndrome helicase Nucleic Acids Research. 36: 4242-4256. PMID 18583366 DOI: 10.1093/Nar/Gkn385 |
0.536 |
|
| 2008 |
Opresko PL. Telomere ResQue and preservation--roles for the Werner syndrome protein and other RecQ helicases. Mechanisms of Ageing and Development. 129: 79-90. PMID 18054793 DOI: 10.1016/J.Mad.2007.10.007 |
0.521 |
|
| 2007 |
Opresko PL, Calvo JP, von Kobbe C. Role for the Werner syndrome protein in the promotion of tumor cell growth. Mechanisms of Ageing and Development. 128: 423-36. PMID 17624410 DOI: 10.1016/J.Mad.2007.05.009 |
0.338 |
|
| 2006 |
Eller MS, Liao X, Liu S, Hanna K, Bäckvall H, Opresko PL, Bohr VA, Gilchrest BA. A role for WRN in telomere-based DNA damage responses. Proceedings of the National Academy of Sciences of the United States of America. 103: 15073-8. PMID 17015833 DOI: 10.1073/Pnas.0607332103 |
0.549 |
|
| 2006 |
Brosh RM, Opresko PL, Bohr VA. Enzymatic mechanism of the WRN helicase/nuclease. Methods in Enzymology. 409: 52-85. PMID 16793395 DOI: 10.1016/S0076-6879(05)09004-X |
0.498 |
|
| 2006 |
Cheng WH, Kusumoto R, Opresko PL, Sui X, Huang S, Nicolette ML, Paull TT, Campisi J, Seidman M, Bohr VA. Collaboration of Werner syndrome protein and BRCA1 in cellular responses to DNA interstrand cross-links. Nucleic Acids Research. 34: 2751-60. PMID 16714450 DOI: 10.1093/Nar/Gkl362 |
0.574 |
|
| 2006 |
Zhang P, Furukawa K, Opresko PL, Xu X, Bohr VA, Mattson MP. TRF2 dysfunction elicits DNA damage responses associated with senescence in proliferating neural cells and differentiation of neurons. Journal of Neurochemistry. 97: 567-81. PMID 16539655 DOI: 10.1111/J.1471-4159.2006.03779.X |
0.465 |
|
| 2006 |
Harrigan JA, Wilson DM, Prasad R, Opresko PL, Beck G, May A, Wilson SH, Bohr VA. The Werner syndrome protein operates in base excision repair and cooperates with DNA polymerase beta. Nucleic Acids Research. 34: 745-54. PMID 16449207 DOI: 10.1093/Nar/Gkj475 |
0.527 |
|
| 2006 |
Muftuoglu M, Wong HK, Imam SZ, Wilson DM, Bohr VA, Opresko PL. Telomere repeat binding factor 2 interacts with base excision repair proteins and stimulates DNA synthesis by DNA polymerase beta. Cancer Research. 66: 113-24. PMID 16397223 DOI: 10.1158/0008-5472.Can-05-2742 |
0.586 |
|
| 2005 |
Opresko PL, Mason PA, Podell ER, Lei M, Hickson ID, Cech TR, Bohr VA. POT1 stimulates RecQ helicases WRN and BLM to unwind telomeric DNA substrates. The Journal of Biological Chemistry. 280: 32069-80. PMID 16030011 DOI: 10.1074/Jbc.M505211200 |
0.581 |
|
| 2005 |
Opresko PL, Fan J, Danzy S, Wilson DM, Bohr VA. Oxidative damage in telomeric DNA disrupts recognition by TRF1 and TRF2. Nucleic Acids Research. 33: 1230-9. PMID 15731343 DOI: 10.1093/Nar/Gki273 |
0.59 |
|
| 2005 |
Lee JW, Harrigan J, Opresko PL, Bohr VA. Pathways and functions of the Werner syndrome protein. Mechanisms of Ageing and Development. 126: 79-86. PMID 15610765 DOI: 10.1016/J.Mad.2004.09.011 |
0.371 |
|
| 2004 |
Opresko PL, Otterlei M, Graakjaer J, Bruheim P, Dawut L, Kølvraa S, May A, Seidman MM, Bohr VA. The Werner syndrome helicase and exonuclease cooperate to resolve telomeric D loops in a manner regulated by TRF1 and TRF2. Molecular Cell. 14: 763-74. PMID 15200954 DOI: 10.1016/J.Molcel.2004.05.023 |
0.507 |
|
| 2004 |
Cheng WH, von Kobbe C, Opresko PL, Arthur LM, Komatsu K, Seidman MM, Carney JP, Bohr VA. Linkage between Werner syndrome protein and the Mre11 complex via Nbs1. The Journal of Biological Chemistry. 279: 21169-76. PMID 15026416 DOI: 10.1074/Jbc.M312770200 |
0.423 |
|
| 2003 |
Laine JP, Opresko PL, Indig FE, Harrigan JA, von Kobbe C, Bohr VA. Werner protein stimulates topoisomerase I DNA relaxation activity. Cancer Research. 63: 7136-46. PMID 14612507 |
0.485 |
|
| 2003 |
von Kobbe C, Harrigan JA, May A, Opresko PL, Dawut L, Cheng WH, Bohr VA. Central role for the Werner syndrome protein/poly(ADP-ribose) polymerase 1 complex in the poly(ADP-ribosyl)ation pathway after DNA damage. Molecular and Cellular Biology. 23: 8601-13. PMID 14612404 DOI: 10.1128/Mcb.23.23.8601-8613.2003 |
0.555 |
|
| 2003 |
Cheng WH, von Kobbe C, Opresko PL, Fields KM, Ren J, Kufe D, Bohr VA. Werner syndrome protein phosphorylation by abl tyrosine kinase regulates its activity and distribution. Molecular and Cellular Biology. 23: 6385-95. PMID 12944467 DOI: 10.1128/Mcb.23.18.6385-6395.2003 |
0.41 |
|
| 2003 |
Opresko PL, Cheng WH, von Kobbe C, Harrigan JA, Bohr VA. Werner syndrome and the function of the Werner protein; what they can teach us about the molecular aging process. Carcinogenesis. 24: 791-802. PMID 12771022 DOI: 10.1093/Carcin/Bgg034 |
0.455 |
|
| 2003 |
Harrigan JA, Opresko PL, von Kobbe C, Kedar PS, Prasad R, Wilson SH, Bohr VA. The Werner syndrome protein stimulates DNA polymerase beta strand displacement synthesis via its helicase activity. The Journal of Biological Chemistry. 278: 22686-95. PMID 12665521 DOI: 10.1074/Jbc.M213103200 |
0.519 |
|
| 2002 |
Opresko PL, von Kobbe C, Laine JP, Harrigan J, Hickson ID, Bohr VA. Telomere-binding protein TRF2 binds to and stimulates the Werner and Bloom syndrome helicases. The Journal of Biological Chemistry. 277: 41110-9. PMID 12181313 DOI: 10.1074/Jbc.M205396200 |
0.465 |
|
| 2002 |
Bohr VA, Brosh RM, von Kobbe C, Opresko P, Karmakar P. Pathways defective in the human premature aging disease Werner syndrome. Biogerontology. 3: 89-94. PMID 12014850 DOI: 10.1023/A:1015223917491 |
0.457 |
|
| 2002 |
von Kobbe C, Karmakar P, Dawut L, Opresko P, Zeng X, Brosh RM, Hickson ID, Bohr VA. Colocalization, physical, and functional interaction between Werner and Bloom syndrome proteins. The Journal of Biological Chemistry. 277: 22035-44. PMID 11919194 DOI: 10.1074/Jbc.M200914200 |
0.391 |
|
| 2001 |
Brosh RM, Von Kobbe C, Sommers JA, Karmakar P, Opresko PL, Piotrowski J, Dianova I, Dianov GL, Bohr VA. Werner syndrome protein interacts with human flap endonuclease 1 and stimulates its cleavage activity Embo Journal. 20: 5791-5801. PMID 11598021 DOI: 10.1093/Emboj/20.20.5791 |
0.558 |
|
| 2001 |
Opresko PL, Laine JP, Brosh RM, Seidman MM, Bohr VA. Coordinate Action of the Helicase and 3′ to 5′ Exonuclease of Werner Syndrome Protein Journal of Biological Chemistry. 276: 44677-44687. PMID 11572872 DOI: 10.1074/Jbc.M107548200 |
0.582 |
|
| 2000 |
Opresko PL, Shiman R, Eckert KA. Hydrophobic interactions in the hinge domain of DNA polymerase beta are important but not sufficient for maintaining fidelity of DNA synthesis. Biochemistry. 39: 11399-407. PMID 10985785 DOI: 10.1021/Bi000698T |
0.672 |
|
| 1999 |
Eckert KA, Opresko PL. DNA polymerase mutagenic bypass and proofreading of endogenous DNA lesions. Mutation Research. 424: 221-36. PMID 10064863 DOI: 10.1016/S0027-5107(99)00021-4 |
0.697 |
|
| 1998 |
Opresko PL, Sweasy JB, Eckert KA. The mutator form of polymerase beta with amino acid substitution at tyrosine 265 in the hinge region displays an increase in both base substitution and frame shift errors. Biochemistry. 37: 2111-9. PMID 9485358 DOI: 10.1021/Bi9722711 |
0.648 |
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