Year |
Citation |
Score |
2023 |
Bosch AJT, Keller L, Steiger L, Rohm TV, Wiedemann SJ, Low AJY, Stawiski M, Rachid L, Roux J, Konrad D, Wueest S, Tugues S, Greter M, Böni-Schnetzler M, Meier DT, et al. CSF1R inhibition with PLX5622 affects multiple immune cell compartments and induces tissue-specific metabolic effects in lean mice. Diabetologia. PMID 37792013 DOI: 10.1007/s00125-023-06007-1 |
0.306 |
|
2023 |
Kucharczyk P, Albano G, Deisl C, Ho TM, Bargagli M, Anderegg M, Wueest S, Konrad D, Fuster DG. Thiazides Attenuate Insulin Secretion Through Inhibition of Mitochondrial Carbonic Anhydrase 5b in β-islet Cells in Mice. Journal of the American Society of Nephrology : Jasn. PMID 36927842 DOI: 10.1681/ASN.0000000000000122 |
0.459 |
|
2022 |
van Krieken PP, Roos J, Fischer-Posovszky P, Wueest S, Konrad D. Oncostatin M promotes lipolysis in white adipocytes. Adipocyte. 11: 315-324. PMID 35531859 DOI: 10.1080/21623945.2022.2075129 |
0.468 |
|
2022 |
Rohm TV, Keller L, Bosch AJT, AlAsfoor S, Baumann Z, Thomas A, Wiedemann SJ, Steiger L, Dalmas E, Wehner J, Rachid L, Mooser C, Yilmaz B, Fernandez Trigo N, Jauch AJ, ... ... Konrad D, et al. Targeting colonic macrophages improves glycemic control in high-fat diet-induced obesity. Communications Biology. 5: 370. PMID 35440795 DOI: 10.1038/s42003-022-03305-z |
0.405 |
|
2020 |
Merry TL, Hedges CP, Masson SW, Laube B, Pöhlmann D, Wueest S, Walsh ME, Arnold M, Langhans W, Konrad D, Zarse K, Ristow M. Partial impairment of insulin receptor expression mimics fasting to prevent diet-induced fatty liver disease. Nature Communications. 11: 2080. PMID 32350271 DOI: 10.1038/S41467-020-15623-Z |
0.413 |
|
2018 |
Grandl G, Straub L, Rudigier C, Arnold M, Wueest S, Konrad D, Wolfrum C. Short-term feeding of a ketogenic diet induces more severe hepatic insulin resistance than a obesogenic high-fat diet. The Journal of Physiology. PMID 30089335 DOI: 10.1113/JP275173 |
0.493 |
|
2018 |
Šestan M, Marinović S, Kavazović I, Cekinović Đ, Wueest S, Turk Wensveen T, Brizić I, Jonjić S, Konrad D, Wensveen FM, Polić B. Virus-Induced Interferon-γ Causes Insulin Resistance in Skeletal Muscle and Derails Glycemic Control in Obesity. Immunity. PMID 29958802 DOI: 10.1016/j.immuni.2018.05.005 |
0.398 |
|
2017 |
Wueest S, Laesser CI, Böni-Schnetzler M, Item F, Lucchini FC, Borsigova M, Müller W, Donath MY, Konrad D. IL-6-type Cytokine Signaling in Adipocytes Induces Intestinal GLP-1 Secretion. Diabetes. PMID 29066599 DOI: 10.2337/db17-0637 |
0.401 |
|
2017 |
Dror E, Dalmas E, Meier DT, Wueest S, Thévenet J, Thienel C, Timper K, Nordmann TM, Traub S, Schulze F, Item F, Vallois D, Pattou F, Kerr-Conte J, Lavallard V, ... ... Konrad D, et al. Postprandial macrophage-derived IL-1β stimulates insulin, and both synergistically promote glucose disposal and inflammation. Nature Immunology. PMID 28092375 DOI: 10.1038/ni.3659 |
0.393 |
|
2016 |
Wueest S, Item F, Lucchini FC, Challa TD, Müller W, Blüher M, Konrad D. Mesenteric Fat Lipolysis Mediates Obesity-Associated Hepatic Steatosis and Insulin Resistance. Diabetes. 65: 140-8. PMID 26384383 DOI: 10.2337/db15-0941 |
0.357 |
|
2015 |
Chin SH, Item F, Wueest S, Zhou Z, Wiedemann MS, Gai Z, Schoenle EJ, Kullak-Ublick GA, Al-Hasani H, Konrad D. Opposing effects of reduced kidney mass on liver and skeletal muscle insulin sensitivity in obese mice. Diabetes. 64: 1131-41. PMID 25325737 DOI: 10.2337/db14-0779 |
0.491 |
|
2014 |
Wiedemann MS, Wueest S, Grob A, Item F, Schoenle EJ, Konrad D. Short-term HFD does not alter lipolytic function of adipocytes. Adipocyte. 3: 115-20. PMID 24719784 DOI: 10.4161/adip.27575 |
0.417 |
|
2014 |
Wueest S, Mueller R, Blüher M, Item F, Chin AS, Wiedemann MS, Takizawa H, Kovtonyuk L, Chervonsky AV, Schoenle EJ, Manz MG, Konrad D. Fas (CD95) expression in myeloid cells promotes obesity‐induced muscle insulin resistance. Embo Molecular Medicine. 6: 43-56. PMID 24203314 DOI: 10.1002/emmm.201302962 |
0.451 |
|
2014 |
Blüher M, Klöting N, Wueest S, Schoenle EJ, Schön MR, Dietrich A, Fasshauer M, Stumvoll M, Konrad D. Fas and FasL expression in human adipose tissue is related to obesity, insulin resistance, and type 2 diabetes. The Journal of Clinical Endocrinology and Metabolism. 99: E36-44. PMID 24178789 DOI: 10.1210/jc.2013-2488 |
0.335 |
|
2013 |
Wiedemann MS, Wueest S, Item F, Schoenle EJ, Konrad D. Adipose tissue inflammation contributes to short-term high-fat diet-induced hepatic insulin resistance. American Journal of Physiology. Endocrinology and Metabolism. 305: E388-95. PMID 23736545 DOI: 10.1152/ajpendo.00179.2013 |
0.383 |
|
2013 |
Hadad N, Burgazliev O, Elgazar-Carmon V, Solomonov Y, Wueest S, Item F, Konrad D, Rudich A, Levy R. Induction of cytosolic phospholipase a2α is required for adipose neutrophil infiltration and hepatic insulin resistance early in the course of high-fat feeding. Diabetes. 62: 3053-63. PMID 23670971 DOI: 10.2337/db12-1300 |
0.436 |
|
2012 |
Wueest S, Schoenle EJ, Konrad D. Depot-specific differences in adipocyte insulin sensitivity in mice are diet- and function-dependent. Adipocyte. 1: 153-156. PMID 23700524 DOI: 10.4161/adip.19910 |
0.475 |
|
2011 |
Ellingsgaard H, Hauselmann I, Schuler B, Habib AM, Baggio LL, Meier DT, Eppler E, Bouzakri K, Wueest S, Muller YD, Hansen AM, Reinecke M, Konrad D, Gassmann M, Reimann F, et al. Interleukin-6 enhances insulin secretion by increasing glucagon-like peptide-1 secretion from L cells and alpha cells. Nature Medicine. 17: 1481-9. PMID 22037645 DOI: 10.1038/Nm.2513 |
0.343 |
|
2010 |
Wueest S, Rapold RA, Schoenle EJ, Konrad D. Fas activation in adipocytes impairs insulin-stimulated glucose uptake by reducing Akt. Febs Letters. 584: 4187-92. PMID 20828573 DOI: 10.1016/j.febslet.2010.08.052 |
0.584 |
|
2010 |
Nov O, Kohl A, Lewis EC, Bashan N, Dvir I, Ben-Shlomo S, Fishman S, Wueest S, Konrad D, Rudich A. Interleukin-1beta may mediate insulin resistance in liver-derived cells in response to adipocyte inflammation. Endocrinology. 151: 4247-56. PMID 20660063 DOI: 10.1210/en.2010-0340 |
0.384 |
|
2010 |
Zini E, Osto M, Konrad D, Franchini M, Sieber-Ruckstuhl NS, Kaufmann K, Guscetti F, Ackermann M, Lutz TA, Reusch CE. 10-day hyperlipidemic clamp in cats: effects on insulin sensitivity, inflammation, and glucose metabolism-related genes. Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et MéTabolisme. 42: 340-7. PMID 20162504 DOI: 10.1055/s-0030-1248251 |
0.51 |
|
2010 |
Wueest S, Rapold RA, Schumann DM, Rytka JM, Schildknecht A, Nov O, Chervonsky AV, Rudich A, Schoenle EJ, Donath MY, Konrad D. Deletion of Fas in adipocytes relieves adipose tissue inflammation and hepatic manifestations of obesity in mice. The Journal of Clinical Investigation. 120: 191-202. PMID 19955656 DOI: 10.1172/JCI38388 |
0.361 |
|
2009 |
Wueest S, Rapold RA, Rytka JM, Schoenle EJ, Konrad D. Basal lipolysis, not the degree of insulin resistance, differentiates large from small isolated adipocytes in high-fat fed mice Diabetologia. 52: 541-546. PMID 19048227 DOI: 10.1007/s00125-008-1223-5 |
0.435 |
|
2007 |
Konrad D, Rudich A, Schoenle EJ. Improved glucose tolerance in mice receiving intraperitoneal transplantation of normal fat tissue Diabetologia. 50: 833-839. PMID 17334653 DOI: 10.1007/s00125-007-0596-1 |
0.412 |
|
2007 |
Schumann DM, Maedler K, Franklin I, Konrad D, Størling J, Böni-Schnetzler M, Gjinovci A, Kurrer MO, Gauthier BR, Bosco D, Andres A, Berney T, Greter M, Becher B, Chervonsky AV, et al. The Fas pathway is involved in pancreatic beta cell secretory function. Proceedings of the National Academy of Sciences of the United States of America. 104: 2861-6. PMID 17299038 DOI: 10.1073/pnas.0611487104 |
0.411 |
|
2005 |
Konrad D. Utilization of the insulin-signaling network in the metabolic actions of alpha-lipoic acid-reduction or oxidation? Antioxidants & Redox Signaling. 7: 1032-9. PMID 15998258 DOI: 10.1089/ars.2005.7.1032 |
0.424 |
|
2005 |
Konrad D, Rudich A, Bilan PJ, Patel N, Richardson C, Witters LA, Klip A. Troglitazone causes acute mitochondrial membrane depolarisation and an AMPK-mediated increase in glucose phosphorylation in muscle cells. Diabetologia. 48: 954-66. PMID 15834551 DOI: 10.1007/s00125-005-1713-7 |
0.586 |
|
2005 |
Wijesekara N, Konrad D, Eweida M, Jefferies C, Liadis N, Giacca A, Crackower M, Suzuki A, Mak TW, Kahn CR, Klip A, Woo M. Muscle-specific Pten deletion protects against insulin resistance and diabetes. Molecular and Cellular Biology. 25: 1135-45. PMID 15657439 DOI: 10.1128/Mcb.25.3.1135-1145.2005 |
0.659 |
|
2005 |
Konrad D, Rudich A, Klip A. Insulin-Mediated Regulation of Glucose Metabolism Insulin Resistance: Insulin Action and Its Disturbances in Disease. 63-85. DOI: 10.1002/0470011327.ch2 |
0.642 |
|
2003 |
Konrad D, Daneman D, Kirby M, Wherrett D. Cardiac failure after initiation of insulin treatment in diabetic patients with beta-thalassemia major. The Journal of Pediatrics. 143: 541-2. PMID 14571237 DOI: 10.1067/S0022-3476(03)00414-1 |
0.432 |
|
2003 |
Lemieux K, Konrad D, Klip A, Marette A. The AMP-activated protein kinase activator AICAR does not induce GLUT4 translocation to transverse tubules but stimulates glucose uptake and p38 mitogen-activated protein kinases alpha and beta in skeletal muscle. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 17: 1658-65. PMID 12958172 DOI: 10.1096/Fj.02-1125Com |
0.642 |
|
2003 |
Rudich A, Konrad D, Török D, Ben-Romano R, Huang C, Niu W, Garg RR, Wijesekara N, Germinario RJ, Bilan PJ, Klip A. Indinavir uncovers different contributions of GLUT4 and GLUT1 towards glucose uptake in muscle and fat cells and tissues. Diabetologia. 46: 649-58. PMID 12712244 DOI: 10.1007/S00125-003-1080-1 |
0.651 |
|
2002 |
Konrad D, Bilan PJ, Nawaz Z, Sweeney G, Niu W, Liu Z, Antonescu CN, Rudich A, Klip A. Need for GLUT4 activation to reach maximum effect of insulin-mediated glucose uptake in brown adipocytes isolated from GLUT4myc-expressing mice. Diabetes. 51: 2719-26. PMID 12196464 DOI: 10.2337/Diabetes.51.9.2719 |
0.704 |
|
2001 |
Sweeney G, Keen J, Somwar R, Konrad D, Garg R, Klip A. High leptin levels acutely inhibit insulin-stimulated glucose uptake without affecting glucose transporter 4 translocation in l6 rat skeletal muscle cells. Endocrinology. 142: 4806-12. PMID 11606447 DOI: 10.1210/Endo.142.11.8496 |
0.702 |
|
2001 |
Konrad D, Somwar R, Sweeney G, Yaworsky K, Hayashi M, Ramlal T, Klip A. The antihyperglycemic drug alpha-lipoic acid stimulates glucose uptake via both GLUT4 translocation and GLUT4 activation: potential role of p38 mitogen-activated protein kinase in GLUT4 activation. Diabetes. 50: 1464-71. PMID 11375349 DOI: 10.2337/Diabetes.50.6.1464 |
0.663 |
|
2000 |
Konrad D, Sobetzko D, Schmitt B, Schoenle EJ. Insulin-dependent diabetes mellitus induced by the antitussive agent dextromethorphan [3] Diabetologia. 43: 261-262. PMID 10753054 |
0.325 |
|
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