| Year |
Citation |
Score |
| 2023 |
Guan H, Nuth M, Isaacs SN, Xiao Y, Scott RW, Parker MH, Strobel ED, Kulp JL, Bailey TR, Reitz AB, Ricciardi RP. A small molecule that targets the processivity factor of molluscum contagiosum virus has therapeutic potential. Antiviral Research. 105520. PMID 36603771 DOI: 10.1016/j.antiviral.2022.105520 |
0.308 |
|
| 2020 |
Xiao Y, Zeng Y, Schante C, Joshi SB, Buchman GW, Volkin DB, Middaugh CR, Isaacs SN. Short-term and longer-term protective immune responses generated by subunit vaccination with smallpox A33, B5, L1 or A27 proteins adjuvanted with aluminum hydroxide and CpG in mice challenged with vaccinia virus. Vaccine. PMID 32741672 DOI: 10.1016/J.Vaccine.2020.07.018 |
0.486 |
|
| 2019 |
Isaacs SN. Working Safely with Vaccinia Virus: Laboratory Technique and Review of Published Cases of Accidental Laboratory Infections with Poxviruses. Methods in Molecular Biology (Clifton, N.J.). 2023: 1-27. PMID 31240668 DOI: 10.1007/978-1-4939-9593-6_1 |
0.517 |
|
| 2018 |
Nuth M, Guan H, Xiao Y, Kulp JL, Parker MH, Strobel ED, Isaacs SN, Scott RW, Reitz AB, Ricciardi RP. Mutation and structure guided discovery of an antiviral small molecule that mimics an essential C-terminal tripeptide of the vaccinia D4 processivity factor. Antiviral Research. PMID 30578797 DOI: 10.1016/J.Antiviral.2018.12.011 |
0.451 |
|
| 2017 |
Reyes ED, Kulej K, Pancholi NJ, Akhtar LN, Avgousti DC, Kim ET, Bricker DK, Spruce LA, Koniski SA, Seeholzer SH, Isaacs SN, Garcia BA, Weitzman MD. Identifying host factors associated with DNA replicated during virus infection. Molecular & Cellular Proteomics : McP. PMID 28972080 DOI: 10.1074/Mcp.M117.067116 |
0.518 |
|
| 2014 |
Guan H, Nuth M, Zhukovskaya N, Saw YL, Bell E, Isaacs SN, Ricciardi RP. A novel target and approach for identifying antivirals against molluscum contagiosum virus. Antimicrobial Agents and Chemotherapy. 58: 7383-9. PMID 25267668 DOI: 10.1128/Aac.03660-14 |
0.345 |
|
| 2013 |
Xiao Y, Zeng Y, Alexander E, Mehta S, Joshi SB, Buchman GW, Volkin DB, Middaugh CR, Isaacs SN. Adsorption of recombinant poxvirus L1-protein to aluminum hydroxide/CpG vaccine adjuvants enhances immune responses and protection of mice from vaccinia virus challenge. Vaccine. 31: 319-26. PMID 23153450 DOI: 10.1016/J.Vaccine.2012.11.007 |
0.382 |
|
| 2012 |
Wang LS, Lynn RC, Cheng G, Alexander E, Kapoor V, Moon EK, Sun J, Fridlender ZG, Isaacs SN, Thorne SH, Albelda SM. Treating Tumors With a Vaccinia Virus Expressing IFNβ Illustrates the Complex Relationships Between Oncolytic Ability and Immunogenicity. Molecular Therapy : the Journal of the American Society of Gene Therapy. 20: 736-748. PMID 28160613 DOI: 10.1038/mt.2011.228 |
0.312 |
|
| 2012 |
Xiao Y, Isaacs SN. Enzyme-linked immunosorbent assay (ELISA) and blocking with bovine serum albumin (BSA)--not all BSAs are alike. Journal of Immunological Methods. 384: 148-51. PMID 22732194 DOI: 10.1016/J.Jim.2012.06.009 |
0.35 |
|
| 2012 |
Isaacs SN. Working safely with vaccinia virus: laboratory technique and review of published cases of accidental laboratory infections. Methods in Molecular Biology (Clifton, N.J.). 890: 1-22. PMID 22688758 DOI: 10.1007/978-1-61779-876-4_1 |
0.507 |
|
| 2012 |
Hudson PN, Self J, Weiss S, Braden Z, Xiao Y, Girgis NM, Emerson G, Hughes C, Sammons SA, Isaacs SN, Damon IK, Olson VA. Elucidating the role of the complement control protein in monkeypox pathogenicity. Plos One. 7: e35086. PMID 22496894 DOI: 10.1371/Journal.Pone.0035086 |
0.756 |
|
| 2012 |
Wang LC, Lynn RC, Cheng G, Alexander E, Kapoor V, Moon EK, Sun J, Fridlender ZG, Isaacs SN, Thorne SH, Albelda SM. Treating tumors with a vaccinia virus expressing IFNβ illustrates the complex relationships between oncolytic ability and immunogenicity. Molecular Therapy : the Journal of the American Society of Gene Therapy. 20: 736-48. PMID 22008913 DOI: 10.1038/Mt.2011.228 |
0.421 |
|
| 2011 |
Dehaven BC, Gupta K, Isaacs SN. The vaccinia virus A56 protein: a multifunctional transmembrane glycoprotein that anchors two secreted viral proteins. The Journal of General Virology. 92: 1971-80. PMID 21715594 DOI: 10.1099/Vir.0.030460-0 |
0.786 |
|
| 2011 |
Cohen ME, Xiao Y, Eisenberg RJ, Cohen GH, Isaacs SN. Antibody against extracellular vaccinia virus (EV) protects mice through complement and Fc receptors. Plos One. 6: e20597. PMID 21687676 DOI: 10.1371/Journal.Pone.0020597 |
0.452 |
|
| 2011 |
Girgis NM, Dehaven BC, Xiao Y, Alexander E, Viner KM, Isaacs SN. The Vaccinia virus complement control protein modulates adaptive immune responses during infection. Journal of Virology. 85: 2547-56. PMID 21191012 DOI: 10.1128/Jvi.01474-10 |
0.707 |
|
| 2011 |
Isaacs SN. A stimulating way to improve T cell responses to poxvirus-vectored vaccines. The Journal of Clinical Investigation. 121: 19-21. PMID 21183782 DOI: 10.1172/Jci45726 |
0.405 |
|
| 2010 |
Xiao Y, Isaacs SN. Therapeutic Vaccines and Antibodies for Treatment of Orthopoxvirus Infections. Viruses. 2: 2381-2403. PMID 21197387 DOI: 10.3390/V2102381 |
0.357 |
|
| 2010 |
DeHaven BC, Girgis NM, Xiao Y, Hudson PN, Olson VA, Damon IK, Isaacs SN. Poxvirus complement control proteins are expressed on the cell surface through an intermolecular disulfide bridge with the viral A56 protein. Journal of Virology. 84: 11245-54. PMID 20719953 DOI: 10.1128/Jvi.00372-10 |
0.721 |
|
| 2010 |
Buchman GW, Cohen ME, Xiao Y, Richardson-Harman N, Silvera P, DeTolla LJ, Davis HL, Eisenberg RJ, Cohen GH, Isaacs SN. A protein-based smallpox vaccine protects non-human primates from a lethal monkeypox virus challenge. Vaccine. 28: 6627-36. PMID 20659519 DOI: 10.1016/J.Vaccine.2010.07.030 |
0.48 |
|
| 2010 |
Wang LS, Saloura V, Alexander E, Cheng G, Kapoor V, Vile R, Thorne SH, Isaacs SN, Albelda SM. Abstract 1513: Pre-clinical evaluation of two oncolytic viral vectors expressing IFNβ in treatment of thoracic cancer: Vaccinia virus versus vesicular stomatitis virus Cancer Research. 70: 1513-1513. DOI: 10.1158/1538-7445.Am10-1513 |
0.427 |
|
| 2009 |
Mustafa W, Maciag PC, Pan ZK, Weaver JR, Xiao Y, Isaacs SN, Paterson Y. Listeria monocytogenes delivery of HPV-16 major capsid protein L1 induces systemic and mucosal cell-mediated CD4+ and CD8+ T-cell responses after oral immunization. Viral Immunology. 22: 195-204. PMID 19435416 DOI: 10.1089/Vim.2008.0071 |
0.363 |
|
| 2009 |
Zhang L, Lee SY, Beznoussenko GV, Peters PJ, Yang JS, Gilbert HY, Brassd AL, Elledge SJ, Isaacs SN, Moss B, Mironov A, Hsu VW. A role for the host coatomer and KDEL receptor in early vaccinia biogenesis Proceedings of the National Academy of Sciences of the United States of America. 106: 163-168. PMID 19109439 DOI: 10.1073/Pnas.0811631106 |
0.461 |
|
| 2008 |
Weaver JR, Isaacs SN. Monkeypox virus and insights into its immunomodulatory proteins. Immunological Reviews. 225: 96-113. PMID 18837778 DOI: 10.1111/J.1600-065X.2008.00691.X |
0.548 |
|
| 2008 |
Girgis NM, Dehaven BC, Fan X, Viner KM, Shamim M, Isaacs SN. Cell surface expression of the vaccinia virus complement control protein is mediated by interaction with the viral A56 protein and protects infected cells from complement attack. Journal of Virology. 82: 4205-14. PMID 18287241 DOI: 10.1128/Jvi.02426-07 |
0.73 |
|
| 2007 |
Weaver JR, Shamim M, Alexander E, Davies DH, Felgner PL, Isaacs SN. The identification and characterization of a monoclonal antibody to the vaccinia virus E3 protein. Virus Research. 130: 269-74. PMID 17583368 DOI: 10.1016/J.Virusres.2007.05.012 |
0.519 |
|
| 2007 |
Aldaz-Carroll L, Xiao Y, Whitbeck JC, de Leon MP, Lou H, Kim M, Yu J, Reinherz EL, Isaacs SN, Eisenberg RJ, Cohen GH. Major neutralizing sites on vaccinia virus glycoprotein B5 are exposed differently on variola virus ortholog B6. Journal of Virology. 81: 8131-9. PMID 17522205 DOI: 10.1128/Jvi.00374-07 |
0.437 |
|
| 2007 |
Golovkin M, Spitsin S, Andrianov V, Smirnov Y, Xiao Y, Pogrebnyak N, Markley K, Brodzik R, Gleba Y, Isaacs SN, Koprowski H. Smallpox subunit vaccine produced in Planta confers protection in mice. Proceedings of the National Academy of Sciences of the United States of America. 104: 6864-9. PMID 17428917 DOI: 10.1073/Pnas.0701451104 |
0.327 |
|
| 2007 |
Viner KM, Girgis N, Kwak H, Isaacs SN. B5-deficient vaccinia virus as a vaccine vector for the expression of a foreign antigen in vaccinia immune animals. Virology. 361: 356-63. PMID 17188733 DOI: 10.1016/J.Virol.2006.11.020 |
0.766 |
|
| 2007 |
Xiao Y, Aldaz-Carroll L, Ortiz AM, Whitbeck JC, Alexander E, Lou H, Davis HL, Braciale TJ, Eisenberg RJ, Cohen GH, Isaacs SN. A protein-based smallpox vaccine protects mice from vaccinia and ectromelia virus challenges when given as a prime and single boost. Vaccine. 25: 1214-24. PMID 17098336 DOI: 10.1016/J.Vaccine.2006.10.009 |
0.444 |
|
| 2006 |
Izmailyan RA, Huang CY, Mohammad S, Isaacs SN, Chang W. The envelope G3L protein is essential for entry of vaccinia virus into host cells. Journal of Virology. 80: 8402-10. PMID 16912291 DOI: 10.1128/Jvi.00624-06 |
0.622 |
|
| 2006 |
Empig C, Kenner JR, Perret-Gentil M, Youree BE, Bell E, Chen A, Gurwith M, Higgins K, Lock M, Rice AD, Schriewer J, Sinangil F, White E, Buller RM, Dermody TS, ... Isaacs SN, et al. Highly attenuated smallpox vaccine protects rabbits and mice against pathogenic orthopoxvirus challenge Vaccine. 24: 3686-3694. PMID 16430997 DOI: 10.1016/J.Vaccine.2005.03.029 |
0.357 |
|
| 2005 |
Aldaz-Carroll L, Whitbeck JC, Ponce de Leon M, Lou H, Hirao L, Isaacs SN, Moss B, Eisenberg RJ, Cohen GH. Epitope-mapping studies define two major neutralization sites on the vaccinia virus extracellular enveloped virus glycoprotein B5R. Journal of Virology. 79: 6260-71. PMID 15858010 DOI: 10.1128/Jvi.79.10.6260-6271.2005 |
0.5 |
|
| 2005 |
Viner KM, Isaacs SN. Activity of vaccinia virus-neutralizing antibody in the sera of smallpox vaccinees. Microbes and Infection / Institut Pasteur. 7: 579-83. PMID 15848274 DOI: 10.1016/J.Micinf.2005.02.004 |
0.411 |
|
| 2005 |
Sfyroera G, Katragadda M, Morikis D, Isaacs SN, Lambris JD. Electrostatic modeling predicts the activities of orthopoxvirus complement control proteins. Journal of Immunology (Baltimore, Md. : 1950). 174: 2143-51. PMID 15699145 DOI: 10.4049/Jimmunol.174.4.2143 |
0.502 |
|
| 2004 |
Bell E, Shamim M, Whitbeck JC, Sfyroera G, Lambris JD, Isaacs SN. Antibodies against the extracellular enveloped virus B5R protein are mainly responsible for the EEV neutralizing capacity of vaccinia immune globulin. Virology. 325: 425-31. PMID 15246280 DOI: 10.1016/J.Virol.2004.05.004 |
0.56 |
|
| 2004 |
Isaacs SN. Working safely with vaccinia virus: laboratory technique and the role of vaccinia vaccination. Methods in Molecular Biology (Clifton, N.J.). 269: 1-14. PMID 15114003 DOI: 10.1385/1-59259-789-0:001 |
0.496 |
|
| 2004 |
Kwak H, Mustafa W, Speirs K, Abdool AJ, Paterson Y, Isaacs SN. Improved protection conferred by vaccination with a recombinant vaccinia virus that incorporates a foreign antigen into the extracellular enveloped virion. Virology. 322: 337-48. PMID 15110531 DOI: 10.1016/J.Virol.2004.02.007 |
0.532 |
|
| 2003 |
Amorosa VK, Isaacs SN. Separate worlds set to collide: smallpox, vaccinia virus vaccination, and human immunodeficiency virus and acquired immunodeficiency syndrome. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 37: 426-32. PMID 12884168 DOI: 10.1086/375823 |
0.431 |
|
| 2003 |
Mastellos D, Morikis D, Isaacs SN, Holland MC, Strey CW, Lambris JD. Complement: structure, functions, evolution, and viral molecular mimicry. Immunologic Research. 27: 367-86. PMID 12857982 DOI: 10.1385/Ir:27:2-3:367 |
0.392 |
|
| 2003 |
Isaacs SN, Argyropoulos E, Sfyroera G, Mohammad S, Lambris JD. Restoration of complement-enhanced neutralization of vaccinia virus virions by novel monoclonal antibodies raised against the vaccinia virus complement control protein. Journal of Virology. 77: 8256-62. PMID 12857894 DOI: 10.1128/Jvi.77.15.8256-8262.2003 |
0.515 |
|
| 2001 |
Lamikanra A, Pan ZK, Isaacs SN, Wu TC, Paterson Y. Regression of established human papillomavirus type 16 (HPV-16) immortalized tumors in vivo by vaccinia viruses expressing different forms of HPV-16 E7 correlates with enhanced CD8+ T-cell responses that home to the tumor site Journal of Virology. 75: 9654-9664. PMID 11559797 DOI: 10.1128/Jvi.75.20.9654-9664.2001 |
0.352 |
|
| 2001 |
Singh A, Yi Y, Isaacs SN, Kolson DL, Collman RG. Concordant utilization of macrophage entry coreceptors by related variants within an HIV type 1 primary isolate viral swarm Aids Research and Human Retroviruses. 17: 957-963. PMID 11461681 DOI: 10.1089/088922201750290078 |
0.364 |
|
| 2001 |
Yi Y, Singh A, Isaacs SN, Collman RG. A CCR5/CXCR4-independent coreceptor pathway on human macrophages supports efficient SIV env-mediated fusion but not infection: Implications for alternative pathways of viral entry Virology. 284: 142-151. PMID 11352675 DOI: 10.1006/Viro.2001.0904 |
0.42 |
|
| 2000 |
Weissman D, Ni H, Scales D, Dude A, Capodici J, McGibney K, Abdool A, Isaacs SN, Cannon G, Karikó K. HIV gag mRNA transfection of dendritic cells (DC) delivers encoded antigen to MHC class I and II molecules, causes DC maturation, and induces a potent human in vitro primary immune response. Journal of Immunology (Baltimore, Md. : 1950). 165: 4710-7. PMID 11035115 DOI: 10.4049/Jimmunol.165.8.4710 |
0.345 |
|
| 1999 |
Shisler JL, Isaacs SN, Moss B. Vaccinia virus serpin-1 deletion mutant exhibits a host range defect characterized by low levels of intermediate and late mRNAs. Virology. 262: 298-311. PMID 10502509 DOI: 10.1006/Viro.1999.9884 |
0.462 |
|
| 1999 |
Isaacs SN, Yi Y, Singh A, Collman RG. A macrophage fusion assay for rapid screening of cloned HIV-1 Env using dual recombinant vaccinia viruses expressing distinct RNA polymerases Journal of Virological Methods. 81: 55-61. PMID 10488761 DOI: 10.1016/S0166-0934(99)00056-7 |
0.494 |
|
| 1999 |
Yi Y, Isaacs SN, Williams DA, Frank I, Schols D, De Clercq E, Kolson DL, Collman RG. Role of CXCR4 in cell-cell fusion and infection of monocyte-derived macrophages by primary human immunodeficiency virus type 1 (HIV-1) strains: Two distinct mechanisms of HIV-1 dual tropism Journal of Virology. 73: 7117-7125. PMID 10438797 DOI: 10.1128/Jvi.73.9.7117-7125.1999 |
0.379 |
|
| 1998 |
Lorenzo MM, Herrera E, Blasco R, Isaacs SN. Functional analysis of vaccinia virus B5R protein: role of the cytoplasmic tail. Virology. 252: 450-7. PMID 9878625 DOI: 10.1006/Viro.1998.9483 |
0.504 |
|
| 1998 |
Herrera E, Lorenzo MM, Blasco R, Isaacs SN. Functional analysis of vaccinia virus B5R protein: essential role in virus envelopment is independent of a large portion of the extracellular domain. Journal of Virology. 72: 294-302. PMID 9420227 DOI: 10.1128/Jvi.72.1.294-302.1998 |
0.594 |
|
| 1998 |
Sahu A, Isaacs SN, Soulika AM, Lambris JD. Interaction of vaccinia virus complement control protein with human complement proteins: Factor I-mediated degradation of C3b to iC3b1 inactivates the alternative complement pathway Molecular Immunology. 35: 371. DOI: 10.1016/S0161-5890(98)90695-2 |
0.487 |
|
| 1994 |
Carl M, Isaacs SN, Kaur M, He J, Tam AW, Yarbough PO, Reyes GR. Expression of hepatitis E virus putative structural proteins in recombinant vaccinia viruses. Clinical and Diagnostic Laboratory Immunology. 1: 253-256. DOI: 10.1128/cdli.1.2.253-256.1994 |
0.391 |
|
| 1993 |
Wolffe EJ, Isaacs SN, Moss B. Deletion of the vaccinia virus B5R gene encoding a 42-kilodalton membrane glycoprotein inhibits extracellular virus envelope formation and dissemination. Journal of Virology. 67: 4732-4741. DOI: 10.1128/Jvi.67.8.4732-4741.1993 |
0.429 |
|
| 1992 |
Isaacs SN, Kotwal GJ, Moss B. Vaccinia virus complement-control protein prevents antibody-dependent complement-enhanced neutralization of infectivity and contributes to virulence Proceedings of the National Academy of Sciences of the United States of America. 89: 628-632. PMID 1731333 DOI: 10.1073/Pnas.89.2.628 |
0.503 |
|
| 1992 |
Isaacs SN, Wolffe EJ, Payne LG, Moss B. Characterization of a vaccinia virus-encoded 42-kilodalton class I membrane glycoprotein component of the extracellular virus envelope. Journal of Virology. 66: 7217-7224. DOI: 10.1128/jvi.66.12.7217-7224.1992 |
0.34 |
|
| 1991 |
Kaslow DC, Isaacs SN, Quakyi IA, Gwadz RW, Moss B, Keister DB. Induction of Plasmodium falciparum transmission-blocking antibodies by recombinant vaccinia virus. Science (New York, N.Y.). 252: 1310-3. PMID 1925544 DOI: 10.1126/Science.1925544 |
0.464 |
|
| 1990 |
Kotwal GJ, Isaacs SN, McKenzie R, Frank MM, Moss B. Inhibition of the complement cascade by the major secretory protein of vaccinia virus. Science (New York, N.Y.). 250: 827-30. PMID 2237434 DOI: 10.1126/Science.2237434 |
0.504 |
|
| 1990 |
Isaacs SN, Kotwal GJ, Moss B. Reverse guanine phosphoribosyltransferase selection of recombinant vaccinia viruses Virology. 178: 626-630. PMID 2219714 DOI: 10.1016/0042-6822(90)90367-Z |
0.412 |
|
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