Brian Popko - Publications

Affiliations: 
University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Neuroscience Biology

124 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Arellano G, Loda E, Chen Y, Neef T, Cogswell AC, Primer G, Joy G, Kaschke K, Wills S, Podojil JR, Popko B, Balabanov R, Miller SD. Interferon-γ controls aquaporin-4-specific Th17 and B cells in neuromyelitis optica spectrum disorder. Brain : a Journal of Neurology. PMID 37931066 DOI: 10.1093/brain/awad373  0.313
2023 Chen Y, Quan S, Patil V, Kunjamma RB, Tokars HM, Leisten ED, Joy G, Wills S, Chan JR, Wong YC, Popko B. Insights into the mechanism of oligodendrocyte protection and remyelination enhancement by the integrated stress response. Glia. PMID 37203250 DOI: 10.1002/glia.24386  0.441
2023 Chen Y, Quan S, Patil V, Kunjamma RB, Tokars HM, Leisten ED, Chan J, Wong Y, Popko B. Insights into the mechanism of oligodendrocyte protection and remyelination enhancement by the integrated stress response. Biorxiv : the Preprint Server For Biology. PMID 36747743 DOI: 10.1101/2023.01.23.525156  0.438
2022 Titus HE, Xu H, Robinson AP, Patel PA, Chen Y, Fantini D, Eaton V, Karl M, Garrison ED, Rose IVL, Chiang MY, Podojil JR, Balabanov R, Liddelow SA, Miller RH, ... Popko B, et al. Repurposing the cardiac glycoside digoxin to stimulate myelin regeneration in chemically-induced and immune-mediated mouse models of multiple sclerosis. Glia. PMID 35809238 DOI: 10.1002/glia.24231  0.49
2021 Chen Y, Kunjamma RB, Weiner M, Chan JR, Popko B. Prolonging the integrated stress response enhances CNS remyelination in an inflammatory environment. Elife. 10. PMID 33752802 DOI: 10.7554/eLife.65469  0.436
2021 Dorrier CE, Aran D, Haenelt EA, Sheehy RN, Hoi KK, Pintarić L, Chen Y, Lizama CO, Cautivo KM, Weiner GA, Popko B, Fancy SPJ, Arnold TD, Daneman R. CNS fibroblasts form a fibrotic scar in response to immune cell infiltration. Nature Neuroscience. 24: 234-244. PMID 33526922 DOI: 10.1038/s41593-020-00770-9  0.303
2020 Titus HE, Chen Y, Podojil JR, Robinson AP, Balabanov R, Popko B, Miller SD. Pre-clinical and Clinical Implications of "Inside-Out" vs. "Outside-In" Paradigms in Multiple Sclerosis Etiopathogenesis. Frontiers in Cellular Neuroscience. 14: 599717. PMID 33192332 DOI: 10.3389/fncel.2020.599717  0.448
2020 Guehl NJ, Ramos-Torres KM, Linnman C, Moon SH, Dhaynaut M, Wilks MQ, Han PK, Ma C, Neelamegam R, Zhou YP, Popko B, Correia JA, Reich DS, Fakhri GE, Herscovitch P, et al. Evaluation of the potassium channel tracer [F]3F4AP in rhesus macaques. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X20963404. PMID 33090071 DOI: 10.1177/0271678X20963404  0.612
2019 Xu H, Dzhashiashvili Y, Shah A, Kunjamma RB, Weng YL, Elbaz B, Fei Q, Jones JS, Li YI, Zhuang X, Ming GL, He C, Popko B. mA mRNA Methylation Is Essential for Oligodendrocyte Maturation and CNS Myelination. Neuron. PMID 31901304 DOI: 10.1016/J.Neuron.2019.12.013  0.58
2019 Werneburg S, Jung J, Kunjamma RB, Ha SK, Luciano NJ, Willis CM, Gao G, Biscola NP, Havton LA, Crocker SJ, Popko B, Reich DS, Schafer DP. Targeted Complement Inhibition at Synapses Prevents Microglial Synaptic Engulfment and Synapse Loss in Demyelinating Disease. Immunity. PMID 31883839 DOI: 10.1016/J.Immuni.2019.12.004  0.363
2019 Dzhashiashvili Y, Monckton CP, Shah HS, Kunjamma RB, Popko B. The UPR-PERK pathway is not a promising therapeutic target for mutant SOD1-induced ALS. Neurobiology of Disease. PMID 30923003 DOI: 10.1016/J.Nbd.2019.03.024  0.375
2019 Elbaz B, Popko B. Molecular Control of Oligodendrocyte Development. Trends in Neurosciences. PMID 30770136 DOI: 10.1016/J.Tins.2019.01.002  0.536
2019 Chen Y, Podojil JR, Kunjamma RB, Jones J, Weiner M, Lin W, Miller SD, Popko B. Sephin1, which prolongs the integrated stress response, is a promising therapeutic for multiple sclerosis. Brain : a Journal of Neurology. PMID 30657878 DOI: 10.1093/Brain/Awy322  0.525
2018 Brugarolas P, Reich DS, Popko B. Detecting Demyelination by PET: The Lesion as Imaging Target. Molecular Imaging. 17: 1536012118785471. PMID 30039728 DOI: 10.1177/1536012118785471  0.302
2018 Elbaz B, Aaker JD, Isaac S, Kolarzyk A, Brugarolas P, Eden A, Popko B. Phosphorylation State of ZFP24 Controls Oligodendrocyte Differentiation. Cell Reports. 23: 2254-2263. PMID 29791837 DOI: 10.1016/J.Celrep.2018.04.089  0.424
2018 Chen Y, Popko B. Cholesterol crystals impede nerve repair. Science (New York, N.Y.). 359: 635-636. PMID 29439228 DOI: 10.1126/Science.Aar7369  0.498
2018 Brugarolas P, Sánchez-Rodríguez JE, Tsai HM, Basuli F, Cheng SH, Zhang X, Caprariello AV, Lacroix JJ, Freifelder R, Murali D, DeJesus O, Miller RH, Swenson RE, Chen CT, Herscovitch P, ... ... Popko B, et al. Development of a PET radioligand for potassium channels to image CNS demyelination. Scientific Reports. 8: 607. PMID 29330383 DOI: 10.1038/S41598-017-18747-3  0.437
2017 McKenzie AT, Moyon S, Wang M, Katsyv I, Song WM, Zhou X, Dammer EB, Duong DM, Aaker J, Zhao Y, Beckmann N, Wang P, Zhu J, Lah JJ, Seyfried NT, ... ... Popko B, et al. Multiscale network modeling of oligodendrocytes reveals molecular components of myelin dysregulation in Alzheimer's disease. Molecular Neurodegeneration. 12: 82. PMID 29110684 DOI: 10.1186/S13024-017-0219-3  0.461
2017 Clayton BL, Huang A, Kunjamma RB, Solanki A, Popko B. The integrated stress response in hypoxia-induced diffuse white matter injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28720571 DOI: 10.1523/Jneurosci.2738-16.2017  0.399
2017 Khalyfa A, Qiao Z, Gileles-Hillel A, Khalyfa AA, Akbarpour M, Popko B, Gozal D. Activation of Integrated Stress Response and Metabolic Dysfunction in a Murine Model of Sleep Apnea. American Journal of Respiratory Cell and Molecular Biology. PMID 28594573 DOI: 10.1165/Rcmb.2017-0057Oc  0.312
2017 Trzepizur W, Khalyfa A, Qiao Z, Popko B, Gozal D. Integrated stress response activation by sleep fragmentation during late gestation in mice leads to emergence of adverse metabolic phenotype in offspring. Metabolism: Clinical and Experimental. PMID 28139216 DOI: 10.1016/J.Metabol.2017.01.026  0.327
2017 Clayton BL, Huang A, Dukala D, Soliven B, Popko B. Neonatal Hypoxia Results in Peripheral Nerve Abnormalities. The American Journal of Pathology. PMID 28062081 DOI: 10.1016/J.Ajpath.2016.10.003  0.378
2016 Aaker JD, Elbaz B, Wu Y, Looney TJ, Zhang L, Lahn BT, Popko B. Transcriptional Fingerprint of Hypomyelination in Zfp191null and Shiverer (Mbpshi) Mice. Asn Neuro. 8. PMID 27683878 DOI: 10.1177/1759091416670749  0.586
2016 De Rossi P, Buggia-Prévot V, Clayton BL, Vasquez JB, van Sanford C, Andrew RJ, Lesnick R, Botté A, Deyts C, Salem S, Rao E, Rice RC, Parent A, Kar S, Popko B, et al. Predominant expression of Alzheimer's disease-associated BIN1 in mature oligodendrocytes and localization to white matter tracts. Molecular Neurodegeneration. 11: 59. PMID 27488240 DOI: 10.1186/S13024-016-0124-1  0.322
2016 Elbaz B, Traka M, Kunjamma RB, Dukala D, Lutz AB, Anton ES, Barres BA, Soliven B, Popko B. Adenomatous polyposis coli regulates radial axonal sorting and myelination in the PNS. Development (Cambridge, England). PMID 27226321 DOI: 10.1242/Dev.135913  0.522
2016 Clayton BL, Popko B. Endoplasmic reticulum stress and the unfolded protein response in disorders of myelinating glia. Brain Research. PMID 27055915 DOI: 10.1016/J.Brainres.2016.03.046  0.504
2016 Berthoud VM, Minogue PJ, Snabb JI, Dzhashiashvili Y, Novak LA, Zoltoski RK, Popko B, Beyer EC. Connexin23 deletion does not affect lens transparency. Experimental Eye Research. 146: 283-288. PMID 27038752 DOI: 10.1016/J.Exer.2016.03.025  0.321
2016 Way SW, Popko B. Harnessing the integrated stress response for the treatment of multiple sclerosis. The Lancet. Neurology. 15: 434-43. PMID 26873788 DOI: 10.1016/S1474-4422(15)00381-6  0.812
2016 Way SW, Popko B. Harnessing the integrated stress response for the treatment of multiple sclerosis The Lancet Neurology. DOI: 10.1016/S1474-4422(15)00381-6  0.759
2016 Zhang B, McKenzie A, Wang M, Katsyv I, Song W, Zhou X, Popko B, Aaker J, Tredici K, Nave K, Zhu J, Schadt E, Casaccia P. F2-01-01: Oligodendrocyte-Enriched Gene Networks Reveal Novel Pathways and Key Targets in the Pathogenesis of Alzheimer’s Disease Alzheimer's & Dementia. 12: P214-P214. DOI: 10.1016/J.Jalz.2016.06.380  0.314
2015 Traka M, Podojil JR, McCarthy DP, Miller SD, Popko B. Oligodendrocyte death results in immune-mediated CNS demyelination. Nature Neuroscience. PMID 26656646 DOI: 10.1038/Nn.4193  0.573
2015 Hussien Y, Podojil JR, Robinson AP, Lee AS, Miller SD, Popko B. ER Chaperone BiP/GRP78 Is Required for Myelinating Cell Survival and Provides Protection during Experimental Autoimmune Encephalomyelitis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 15921-33. PMID 26631473 DOI: 10.1523/Jneurosci.0693-15.2015  0.605
2015 Way SW, Podojil JR, Clayton BL, Zaremba A, Collins TL, Kunjamma RB, Robinson AP, Brugarolas P, Miller RH, Miller SD, Popko B. Pharmaceutical integrated stress response enhancement protects oligodendrocytes and provides a potential multiple sclerosis therapeutic. Nature Communications. 6: 6532. PMID 25766071 DOI: 10.1038/Ncomms7532  0.808
2014 Brugarolas P, Popko B. Remyelination therapy goes to trial for multiple sclerosis. Neurology® Neuroimmunology & Neuroinflammation. 1: e26. PMID 25340076 DOI: 10.1212/Nxi.0000000000000026  0.432
2014 Wang L, Popko B, Tixier E, Roos RP. Guanabenz, which enhances the unfolded protein response, ameliorates mutant SOD1-induced amyotrophic lateral sclerosis. Neurobiology of Disease. 71: 317-24. PMID 25134731 DOI: 10.1016/J.Nbd.2014.08.010  0.398
2014 Hussien Y, Cavener DR, Popko B. Genetic inactivation of PERK signaling in mouse oligodendrocytes: normal developmental myelination with increased susceptibility to inflammatory demyelination. Glia. 62: 680-91. PMID 24481666 DOI: 10.1002/Glia.22634  0.579
2014 Wang L, Popko B, Roos RP. An enhanced integrated stress response ameliorates mutant SOD1-induced ALS. Human Molecular Genetics. 23: 2629-38. PMID 24368417 DOI: 10.1093/Hmg/Ddt658  0.371
2013 Traka M, Millen KJ, Collins D, Elbaz B, Kidd GJ, Gomez CM, Popko B. WDR81 is necessary for purkinje and photoreceptor cell survival. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 6834-44. PMID 23595742 DOI: 10.1523/Jneurosci.2394-12.2013  0.586
2013 Lin W, Lin Y, Li J, Fenstermaker AG, Way SW, Clayton B, Jamison S, Harding HP, Ron D, Popko B. Oligodendrocyte-specific activation of PERK signaling protects mice against experimental autoimmune encephalomyelitis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 5980-91. PMID 23554479 DOI: 10.1523/Jneurosci.1636-12.2013  0.827
2011 Popko B. Downregulating DR6 to drive remyelination. Nature Medicine. 17: 779-80. PMID 21738152 DOI: 10.1038/Nm0711-779  0.456
2011 Wang L, Popko B, Roos RP. The unfolded protein response in familial amyotrophic lateral sclerosis. Human Molecular Genetics. 20: 1008-15. PMID 21159797 DOI: 10.1093/Hmg/Ddq546  0.406
2010 Traka M, Arasi K, Avila RL, Podojil JR, Christakos A, Miller SD, Soliven B, Popko B. A genetic mouse model of adult-onset, pervasive central nervous system demyelination with robust remyelination. Brain : a Journal of Neurology. 133: 3017-29. PMID 20851998 DOI: 10.1093/Brain/Awq247  0.512
2010 Popko B. Myelin maintenance: axonal support required. Nature Neuroscience. 13: 275-7. PMID 20177417 DOI: 10.1038/Nn0310-275  0.506
2010 Howng SY, Avila RL, Emery B, Traka M, Lin W, Watkins T, Cook S, Bronson R, Davisson M, Barres BA, Popko B. ZFP191 is required by oligodendrocytes for CNS myelination. Genes & Development. 24: 301-11. PMID 20080941 DOI: 10.1101/Gad.1864510  0.539
2010 Howng SY, Douglas DS, Popko B. A G-coupled receptor protein critical for peripheral nerve myelination. Journal of Molecular Cell Biology. 2: 105-6. PMID 20008863 DOI: 10.1093/Jmcb/Mjp047  0.483
2010 Saadat L, Dupree JL, Kilkus J, Han X, Traka M, Proia RL, Dawson G, Popko B. Absence of oligodendroglial glucosylceramide synthesis does not result in CNS myelin abnormalities or alter the dysmyelinating phenotype of CGT-deficient mice. Glia. 58: 391-8. PMID 19705459 DOI: 10.1002/Glia.20930  0.753
2009 Douglas DS, Moran JL, Bermingham JR, Chen XJ, Brindley DN, Soliven B, Beier DR, Popko B. Concurrent Lpin1 and Nrcam mouse mutations result in severe peripheral neuropathy with transitory hindlimb paralysis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 12089-100. PMID 19793967 DOI: 10.1523/Jneurosci.2029-09.2009  0.353
2009 Lin W, Popko B. Endoplasmic reticulum stress in disorders of myelinating cells. Nature Neuroscience. 12: 379-85. PMID 19287390 DOI: 10.1038/Nn.2273  0.521
2009 Douglas DS, Popko B. Mouse forward genetics in the study of the peripheral nervous system and human peripheral neuropathy. Neurochemical Research. 34: 124-37. PMID 18481175 DOI: 10.1007/S11064-008-9719-4  0.331
2008 Traka M, Wollmann RL, Cerda SR, Dugas J, Barres BA, Popko B. Nur7 is a nonsense mutation in the mouse aspartoacylase gene that causes spongy degeneration of the CNS. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 11537-49. PMID 18987190 DOI: 10.1523/Jneurosci.1490-08.2008  0.542
2008 Hitoshi Y, Harris BT, Liu H, Popko B, Israel MA. Spinal glioma: platelet-derived growth factor B-mediated oncogenesis in the spinal cord. Cancer Research. 68: 8507-15. PMID 18922925 DOI: 10.1158/0008-5472.Can-08-1063  0.364
2008 Lin W, Kunkler PE, Harding HP, Ron D, Kraig RP, Popko B. Enhanced integrated stress response promotes myelinating oligodendrocyte survival in response to interferon-gamma. The American Journal of Pathology. 173: 1508-17. PMID 18818381 DOI: 10.2353/Ajpath.2008.080449  0.544
2008 Popko B. Epigenetic control of myelin repair. Nature Neuroscience. 11: 987-8. PMID 18725899 DOI: 10.1038/Nn0908-987  0.464
2008 Baida G, Popko B, Wollmann RL, Stavrou S, Lin W, Tretiakova M, Krausz TN, Roos RP. A subgenomic segment of Theiler's murine encephalomyelitis virus RNA causes demyelination. Journal of Virology. 82: 5879-86. PMID 18400855 DOI: 10.1128/Jvi.02432-07  0.478
2007 Chen XJ, Levedakou EN, Millen KJ, Wollmann RL, Soliven B, Popko B. Proprioceptive sensory neuropathy in mice with a mutation in the cytoplasmic Dynein heavy chain 1 gene. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 14515-24. PMID 18160659 DOI: 10.1523/Jneurosci.4338-07.2007  0.325
2007 Balabanov R, Strand K, Goswami R, McMahon E, Begolka W, Miller SD, Popko B. Interferon-gamma-oligodendrocyte interactions in the regulation of experimental autoimmune encephalomyelitis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 2013-24. PMID 17314297 DOI: 10.1523/Jneurosci.4689-06.2007  0.73
2007 Lin W, Bailey SL, Ho H, Harding HP, Ron D, Miller SD, Popko B. The integrated stress response prevents demyelination by protecting oligodendrocytes against immune-mediated damage. The Journal of Clinical Investigation. 117: 448-56. PMID 17273557 DOI: 10.1172/Jci29571  0.524
2006 Levedakou EN, Popko B. Rewiring enervated: thinking LARGEr than myodystrophy. Journal of Neuroscience Research. 84: 237-43. PMID 16710847 DOI: 10.1002/Jnr.20896  0.416
2006 Balabanov R, Strand K, Kemper A, Lee JY, Popko B. Suppressor of cytokine signaling 1 expression protects oligodendrocytes from the deleterious effects of interferon-gamma. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 5143-52. PMID 16687505 DOI: 10.1523/Jneurosci.0737-06.2006  0.504
2006 Lin W, Kemper A, Dupree JL, Harding HP, Ron D, Popko B. Interferon-gamma inhibits central nervous system remyelination through a process modulated by endoplasmic reticulum stress. Brain : a Journal of Neurology. 129: 1306-18. PMID 16504972 DOI: 10.1093/Brain/Awl044  0.742
2005 Lin W, Harding HP, Ron D, Popko B. Endoplasmic reticulum stress modulates the response of myelinating oligodendrocytes to the immune cytokine interferon-gamma. The Journal of Cell Biology. 169: 603-12. PMID 15911877 DOI: 10.1083/Jcb.200502086  0.519
2005 Levedakou EN, Chen XJ, Soliven B, Popko B. Disruption of the mouse Large gene in the enr and myd mutants results in nerve, muscle, and neuromuscular junction defects. Molecular and Cellular Neurosciences. 28: 757-69. PMID 15797722 DOI: 10.1016/J.Mcn.2004.12.007  0.361
2005 Balabanov R, Popko B. Myelin repair: developmental myelination redux? Nature Neuroscience. 8: 262-4. PMID 15746910 DOI: 10.1038/Nn0305-262  0.542
2004 Dupree JL, Mason JL, Marcus JR, Stull M, Levinson R, Matsushima GK, Popko B. Oligodendrocytes assist in the maintenance of sodium channel clusters independent of the myelin sheath. Neuron Glia Biology. 1: 179-92. PMID 18634596 DOI: 10.1017/S1740925X04000304  0.78
2004 Wang J, Lin W, Popko B, Campbell IL. Inducible production of interferon-gamma in the developing brain causes cerebellar dysplasia with activation of the Sonic hedgehog pathway. Molecular and Cellular Neurosciences. 27: 489-96. PMID 15555926 DOI: 10.1016/J.Mcn.2004.08.004  0.393
2004 Lin W, Kemper A, McCarthy KD, Pytel P, Wang JP, Campbell IL, Utset MF, Popko B. Interferon-gamma induced medulloblastoma in the developing cerebellum. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 10074-83. PMID 15537876 DOI: 10.1523/Jneurosci.2604-04.2004  0.379
2004 Ye P, Popken GJ, Kemper A, McCarthy K, Popko B, D'Ercole AJ. Astrocyte-specific overexpression of insulin-like growth factor-I promotes brain overgrowth and glial fibrillary acidic protein expression Journal of Neuroscience Research. 78: 472-484. PMID 15468174 DOI: 10.1002/Jnr.20288  0.41
2003 Popko B. Notch signaling: a rheostat regulating oligodendrocyte differentiation? Developmental Cell. 5: 668-9. PMID 14602066 DOI: 10.1016/S1534-5807(03)00331-9  0.357
2003 Nie DY, Zhou ZH, Ang BT, Teng FY, Xu G, Xiang T, Wang CY, Zeng L, Takeda Y, Xu TL, Ng YK, Faivre-Sarrailh C, Popko B, Ling EA, Schachner M, et al. Nogo-A at CNS paranodes is a ligand of Caspr: possible regulation of K(+) channel localization. The Embo Journal. 22: 5666-78. PMID 14592966 DOI: 10.1093/Emboj/Cdg570  0.406
2003 Popko B. Myelin: not just a conduit for conduction. Nature Genetics. 33: 327-8. PMID 12610543 DOI: 10.1038/Ng0303-327  0.516
2003 Rosenbluth J, Dupree JL, Popko B. Nodal sodium channel domain integrity depends on the conformation of the paranodal junction, not on the presence of transverse bands. Glia. 41: 318-25. PMID 12528185 DOI: 10.1002/Glia.10179  0.686
2003 Doerflinger NH, Macklin WB, Popko B. Inducible site-specific recombination in myelinating cells. Genesis (New York, N.Y. : 2000). 35: 63-72. PMID 12481300 DOI: 10.1002/Gene.10154  0.532
2002 Marcus J, Popko B. Galactolipids are molecular determinants of myelin development and axo-glial organization. Biochimica Et Biophysica Acta. 1573: 406-13. PMID 12417425 DOI: 10.1016/S0304-4165(02)00410-5  0.765
2002 Ishibashi T, Dupree JL, Ikenaka K, Hirahara Y, Honke K, Peles E, Popko B, Suzuki K, Nishino H, Baba H. A myelin galactolipid, sulfatide, is essential for maintenance of ion channels on myelinated axon but not essential for initial cluster formation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 6507-14. PMID 12151530 DOI: 10.1523/Jneurosci.22-15-06507.2002  0.689
2002 Traka M, Dupree JL, Popko B, Karagogeos D. The neuronal adhesion protein TAG-1 is expressed by Schwann cells and oligodendrocytes and is localized to the juxtaparanodal region of myelinated fibers. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 3016-24. PMID 11943804 DOI: 10.1523/Jneurosci.22-08-03016.2002  0.704
2002 Popko B, Pearl DK, Walker DM, Comas TC, Baerwald KD, Burger PC, Scheithauer BW, Yates AJ. Molecular markers that identify human astrocytomas and oligodendrogliomas. Journal of Neuropathology and Experimental Neurology. 61: 329-38. PMID 11939588 DOI: 10.1093/Jnen/61.4.329  0.345
2002 Honke K, Hirahara Y, Dupree J, Suzuki K, Popko B, Fukushima K, Fukushima J, Nagasawa T, Yoshida N, Wada Y, Taniguchi N. Paranodal junction formation and spermatogenesis require sulfoglycolipids. Proceedings of the National Academy of Sciences of the United States of America. 99: 4227-32. PMID 11917099 DOI: 10.1073/Pnas.032068299  0.729
2002 Marcus J, Dupree JL, Popko B. Myelin-associated glycoprotein and myelin galactolipids stabilize developing axo-glial interactions. The Journal of Cell Biology. 156: 567-77. PMID 11827985 DOI: 10.1083/Jcb.200111047  0.818
2000 Gao X, Gillig TA, Ye P, D'Ercole AJ, Matsushima GK, Popko B. Interferon-γ protects against cuprizone-induced demyelination Molecular and Cellular Neurosciences. 16: 338-349. PMID 11085872 DOI: 10.1006/Mcne.2000.0883  0.557
2000 Marcus J, Dupree JL, Popko B. Effects of galactolipid elimination on oligodendrocyte development and myelination. Glia. 30: 319-28. PMID 10797612 DOI: 10.1002/(Sici)1098-1136(200006)30:4<319::Aid-Glia10>3.0.Co;2-T  0.81
2000 Ezoe T, Vanier MT, Oya Y, Popko B, Tohyama J, Matsuda J, Suzuki K, Suzuki K. Twitcher mice with only a single active galactosylceramide synthase gene exhibit clearly detectable but therapeutically minor phenotypic improvements. Journal of Neuroscience Research. 59: 179-87. PMID 10650876 DOI: 10.1002/(Sici)1097-4547(20000115)59:2<179::Aid-Jnr4>3.0.Co;2-N  0.364
2000 Ezoe T, Vanier MT, Oya Y, Popko B, Tohyama J, Matsuda J, Suzuki K, Suzuki K. Biochemistry and neuropathology of mice doubly deficient in synthesis and degradation of galactosylceramide. Journal of Neuroscience Research. 59: 170-8. PMID 10650875 DOI: 10.1002/(Sici)1097-4547(20000115)59:2<170::Aid-Jnr3>3.0.Co;2-G  0.372
2000 Baerwald KD, Corbin JG, Popko B. Major histocompatibility complex heavy chain accumulation in the endoplasmic reticulum of oligodendrocytes results in myelin abnormalities. Journal of Neuroscience Research. 59: 160-9. PMID 10650874 DOI: 10.1002/(Sici)1097-4547(20000115)59:2<160::Aid-Jnr2>3.0.Co;2-K  0.482
2000 Popko B. Myelin galactolipids: mediators of axon-glial interactions? Glia. 29: 149-53. PMID 10625333 DOI: 10.1002/(Sici)1098-1136(20000115)29:2<149::Aid-Glia8>3.0.Co;2-4  0.51
1999 Dupree JL, Popko B. Genetic dissection of myelin galactolipid function. Journal of Neurocytology. 28: 271-9. PMID 10739570 DOI: 10.1023/A:1007049310758  0.76
1999 Popko B, Dupree JL, Coetzee T, Suzuki K, Suzuki K. Genetic analysis of myelin galactolipid function. Advances in Experimental Medicine and Biology. 468: 237-44. PMID 10635033 DOI: 10.1007/978-1-4615-4685-6_19  0.733
1999 Dupree JL, Girault JA, Popko B. Axo-glial interactions regulate the localization of axonal paranodal proteins. The Journal of Cell Biology. 147: 1145-52. PMID 10601330 DOI: 10.1083/Jcb.147.6.1145  0.708
1999 Coetzee T, Suzuki K, Nave KA, Popko B. Myelination in the absence of galactolipids and proteolipid proteins. Molecular and Cellular Neurosciences. 14: 41-51. PMID 10433816 DOI: 10.1006/Mcne.1999.0768  0.577
1999 Suzuki K, Vanier MT, Coetzee T, Popko B. Drastically abnormal gluco- and galactosylceramide composition does not affect ganglioside metabolism in the brain of mice deficient in galactosylceramide synthase. Neurochemical Research. 24: 471-4. PMID 10227678 DOI: 10.1023/A:1022571410445  0.318
1999 Popko B, Baerwald KD. Oligodendroglial response to the immune cytokine interferon gamma. Neurochemical Research. 24: 331-8. PMID 9972883 DOI: 10.1023/A:1022586726510  0.467
1998 Dupree JL, Coetzee T, Suzuki K, Popko B. Myelin abnormalities in mice deficient in galactocerebroside and sulfatide. Journal of Neurocytology. 27: 649-59. PMID 10447239 DOI: 10.1023/A:1006908013972  0.763
1998 Coetzee T, Dupree JL, Popko B. Demyelination and altered expression of myelin-associated glycoprotein isoforms in the central nervous system of galactolipid-deficient mice. Journal of Neuroscience Research. 54: 613-22. PMID 9843152 DOI: 10.1002/(Sici)1097-4547(19981201)54:5<613::Aid-Jnr6>3.0.Co;2-V  0.772
1998 Dupree JL, Suzuki K, Popko B. Galactolipids in the formation and function of the myelin sheath. Microscopy Research and Technique. 41: 431-40. PMID 9672425 DOI: 10.1002/(Sici)1097-0029(19980601)41:5<431::Aid-Jemt9>3.0.Co;2-S  0.765
1998 Baerwald KD, Popko B. Developing and mature oligodendrocytes respond differently to the immune cytokine interferon-gamma. Journal of Neuroscience Research. 52: 230-9. PMID 9579413 DOI: 10.1002/(Sici)1097-4547(19980415)52:2<230::Aid-Jnr11>3.0.Co;2-B  0.47
1998 Roses AD, Gilbert J, Xu PT, Sullivan P, Popko B, Burkhart DS, Christian-Rothrock T, Saunders AM, Maeda N, Schmechel DE. Cis-acting human ApoE tissue expression element is associated with human pattern of intraneuronal ApoE in transgenic mice. Neurobiology of Aging. 19: S53-8. PMID 9562469 DOI: 10.1016/S0197-4580(98)00030-X  0.345
1998 Coet T, Suzuki K, Popko B. New perspectives on the function of myelin galactolipids Trends in Neurosciences. 21: 126-130. PMID 9530920 DOI: 10.1016/S0166-2236(97)01178-8  0.542
1998 Taniike M, Marcus JR, Nishigaki T, Fujita N, Popko B, Suzuki K, Suzuki K. Suppressed UDP-galactose: ceramide galactosyltransferase and myelin protein mRNA in twitcher mouse brain. Journal of Neuroscience Research. 51: 536-40. PMID 9514207 DOI: 10.1002/(Sici)1097-4547(19980215)51:4<536::Aid-Jnr13>3.0.Co;2-1  0.727
1998 Fujita N, Kemper A, Dupree J, Nakayasu H, Bartsch U, Schachner M, Maeda N, Suzuki K, Suzuki K, Popko B. The Cytoplasmic Domain of the Large Myelin-Associated Glycoprotein Isoform Is Needed for Proper CNS But Not Peripheral Nervous System Myelination The Journal of Neuroscience. 18: 1970-1978. DOI: 10.1523/Jneurosci.18-06-01970.1998  0.746
1998 Dupree JL, Coetzee T, Blight A, Suzuki K, Popko B. Myelin Galactolipids Are Essential for Proper Node of Ranvier Formation in the CNS The Journal of Neuroscience. 18: 1642-1649. DOI: 10.1523/Jneurosci.18-05-01642.1998  0.742
1997 Popko B, Corbin JG, Baerwald KD, Dupree J, Garcia AM. The effects of interferon-gamma on the central nervous system. Molecular Neurobiology. 14: 19-35. PMID 9170099 DOI: 10.1007/Bf02740619  0.678
1997 Taniike M, Marcus JR, Popko B, Suzuki K. Expression of major histocompatibility complex class I antigens in the demyelinating twitcher CNS and PNS. Journal of Neuroscience Research. 47: 539-46. PMID 9067863 DOI: 10.1002/(Sici)1097-4547(19970301)47:5<539::Aid-Jnr9>3.0.Co;2-I  0.684
1996 Xu PT, Schmechel D, Rothrock-Christian T, Burkhart DS, Qiu HL, Popko B, Sullivan P, Maeda N, Saunders AM, Roses AD, Gilbert JR. Human apolipoprotein E2, E3, and E4 isoform-specific transgenic mice: human-like pattern of glial and neuronal immunoreactivity in central nervous system not observed in wild-type mice. Neurobiology of Disease. 3: 229-45. PMID 8980023 DOI: 10.1006/Nbdi.1996.0023  0.366
1996 Corbin JG, Kelly D, Rath EM, Baerwald KD, Suzuki K, Popko B. Targeted CNS expression of interferon-gamma in transgenic mice leads to hypomyelination, reactive gliosis, and abnormal cerebellar development. Molecular and Cellular Neurosciences. 7: 354-70. PMID 8812062 DOI: 10.1006/Mcne.1996.0026  0.546
1996 Fujita N, Suzuki K, Vanier MT, Popko B, Maeda N, Klein A, Henseler M, Sandhoff K, Nakayasu H, Suzuki K. Targeted disruption of the mouse sphingolipid activator protein gene: a complex phenotype, including severe leukodystrophy and wide-spread storage of multiple sphingolipids. Human Molecular Genetics. 5: 711-25. PMID 8776585 DOI: 10.1093/Hmg/5.6.711  0.358
1996 Coetzee T, Fujita N, Dupree J, Shi R, Blight A, Suzuki K, Suzuki K, Popko B. Myelination in the absence of galactocerebroside and sulfatide: normal structure with abnormal function and regional instability. Cell. 86: 209-19. PMID 8706126 DOI: 10.1016/S0092-8674(00)80093-8  0.748
1996 Coetzee T, Li X, Fujita N, Marcus J, Suzuki K, Francke U, Popko B. Molecular cloning, chromosomal mapping, and characterization of the mouse UDP-galactose:ceramide galactosyltransferase gene Genomics. 35: 215-222. PMID 8661123 DOI: 10.1006/Geno.1996.0341  0.609
1995 Goodrum JF, Bouldin TW, Zhang SH, Maeda N, Popko B. Nerve regeneration and cholesterol reutilization occur in the absence of apolipoproteins E and A-I in mice. Journal of Neurochemistry. 64: 408-16. PMID 7798939 DOI: 10.1046/J.1471-4159.1995.64010408.X  0.396
1995 Li Y, Atashi J, Hayes C, Reap E, Hunt S, Popko B. Morphological and molecular response of the MOCH-1 oligodendrocyte cell line to serum and interferon-gamma: possible implications for demyelinating disorders. Journal of Neuroscience Research. 40: 189-98. PMID 7745612 DOI: 10.1002/Jnr.490400207  0.437
1995 Rath EM, Kelly D, Bouldin TW, Popko B. Impaired peripheral nerve regeneration in a mutant strain of mice (Enr) with a Schwann cell defect. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 7226-37. PMID 7472477 DOI: 10.1523/Jneurosci.15-11-07226.1995  0.424
1994 Stahl N, Jurevics H, Morell P, Suzuki K, Popko B. Isolation, characterization, and expression of cDNA clones that encode rat UDP-galactose: ceramide galactosyltransferase. Journal of Neuroscience Research. 38: 234-42. PMID 7521399 DOI: 10.1002/Jnr.490380214  0.387
1994 Kelly D, Chancellor K, Milatovich A, Francke U, Suzuki K, Popko B. Autosomal recessive neuromuscular disorder in a transgenic line of mice The Journal of Neuroscience. 14: 198-207. DOI: 10.1523/Jneurosci.14-01-00198.1994  0.468
1993 Popko B, Goodrum JF, Bouldin TW, Zhang SH, Maeda N. Nerve regeneration occurs in the absence of apolipoprotein E in mice. Journal of Neurochemistry. 60: 1155-8. PMID 8436967 DOI: 10.1111/J.1471-4159.1993.Tb03268.X  0.372
1992 Hayes C, Kelly D, Murayama S, Komiyama A, Suzuki K, Popko B. Expression of the neu oncogene under the transcriptional control of the myelin basic protein gene in transgenic mice: generation of transformed glial cells. Journal of Neuroscience Research. 31: 175-87. PMID 1377283 DOI: 10.1002/Jnr.490310123  0.513
1992 Francke U, Hsieh CL, Kelly D, Lai E, Popko B. Induced reciprocal translocation in transgenic mice near sites of transgene integration. Mammalian Genome. 3: 209-216. PMID 1377063 DOI: 10.1007/Bf00355721  0.323
1992 Shine HD, Readhead C, Popko B, Hood L, Sidman RL. Morphometric analysis of normal, mutant, and transgenic CNS: correlation of myelin basic protein expression to myelinogenesis. Journal of Neurochemistry. 58: 342-9. PMID 1370079 DOI: 10.1111/J.1471-4159.1992.Tb09316.X  0.563
1992 Skinner CA, Kelly D, Kao LR, Nayfeh SN, Popko B, Chae CB. Thyroid-specific and hormone-dependent expression of rat thyroglobulin promoter fused with bacterial chloramphenicol acetyltransferase gene in transgenic mice. Molecular and Cellular Endocrinology. 90: 33-8. PMID 1301397 DOI: 10.1016/0303-7207(92)90098-Q  0.333
1991 You KH, Hsieh CL, Hayes C, Stahl N, Francke U, Popko B. DNA sequence, genomic organization, and chromosomal localization of the mouse peripheral myelin protein zero gene: identification of polymorphic alleles. Genomics. 9: 751-757. PMID 1709914 DOI: 10.1016/0888-7543(91)90370-T  0.326
1990 Toews AD, Lee SY, Popko B, Morell P. Tellurium-induced neuropathy: a model for reversible reductions in myelin protein gene expression. Journal of Neuroscience Research. 26: 501-7. PMID 1700139 DOI: 10.1002/Jnr.490260414  0.457
1990 Stahl N, Harry J, Popko B. Quantitative analysis of myelin protein gene expression during development in the rat sciatic nerve. Brain Research. Molecular Brain Research. 8: 209-12. PMID 1699107 DOI: 10.1016/0169-328X(90)90018-9  0.42
1990 TOEWS AD, WAGNER-RECIO M, HARRY J, POPKO B, MORELL P. Metabolic Alterations during Tellurium-Induced Demyelination and Subsequent Remyelination Annals of the New York Academy of Sciences. 605: 363-364. DOI: 10.1111/J.1749-6632.1990.Tb42412.X  0.347
1990 Fremeau RT, Popko B. In situ analysis of myelin basic protein gene expression in myelin-deficient oligodendrocytes: antisense hnRNA and readthrough transcription. The Embo Journal. 9: 3533-3538. DOI: 10.1002/J.1460-2075.1990.Tb07562.X  0.43
1988 Popko B, Puckett C, Hood L. A novel mutation in myelin-deficient mice results in unstable myelin basic protein gene transcripts Neuron. 1: 221-225. PMID 2483096 DOI: 10.1016/0896-6273(88)90142-0  0.507
1987 Popko B, Puckett C, Lai E, Shine HD, Readhead C, Takahashi N, Hunt SW, Sidman RL, Hood L. Myelin deficient mice: expression of myelin basic protein and generation of mice with varying levels of myelin. Cell. 48: 713-21. PMID 2434243 DOI: 10.1016/0092-8674(87)90249-2  0.579
1987 Readhead C, Popko B, Takahashi N, Shine HD, Saavedra RA, Sidman RL, Hood L. Expression of a myelin basic protein gene in transgenic shiverer mice: correction of the dysmyelinating phenotype. Cell. 48: 703-12. PMID 2434242 DOI: 10.1016/0092-8674(87)90248-0  0.472
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