Year |
Citation |
Score |
2022 |
Al-Shareef W, Brown Y, Bryan C, Shuvaeva E, Bsoul S, Greenman R, Kabaha MM, Ulyanov NB, Skordalakes E, Tzfati Y. Functional Interactions of Telomerase Reverse Transcriptase with the Three-Way Junction and the Template Domains of Telomerase RNA. International Journal of Molecular Sciences. 23. PMID 36142669 DOI: 10.3390/ijms231810757 |
0.34 |
|
2020 |
Aramburu T, Plucinsky S, Skordalakes E. POT1-TPP1 telomere length regulation and disease. Computational and Structural Biotechnology Journal. 18: 1939-1946. PMID 32774788 DOI: 10.1016/J.Csbj.2020.06.040 |
0.374 |
|
2020 |
Ren W, Medeiros N, Warneford-Thomson R, Wulfridge P, Yan Q, Bian J, Sidoli S, Garcia BA, Skordalakes E, Joyce E, Bonasio R, Sarma K. Disruption of ATRX-RNA interactions uncovers roles in ATRX localization and PRC2 function. Nature Communications. 11: 2219. PMID 32376827 DOI: 10.1038/S41467-020-15902-9 |
0.397 |
|
2019 |
Di Sante G, Pagé J, Jiao X, Nawab O, Cristofanilli M, Skordalakes E, Pestell RG. Recent advances with cyclin-dependent kinase inhibitors: therapeutic agents for breast cancer and their role in immuno-oncology. Expert Review of Anticancer Therapy. 1-19. PMID 31219365 DOI: 10.1080/14737140.2019.1615889 |
0.315 |
|
2019 |
Hernandez-Sanchez W, Huang W, Plucinsky B, Garcia-Vazquez N, Robinson NJ, Schiemann WP, Berdis AJ, Skordalakes E, Taylor DJ. A non-natural nucleotide uses a specific pocket to selectively inhibit telomerase activity. Plos Biology. 17: e3000204. PMID 30951520 DOI: 10.1371/Journal.Pbio.3000204 |
0.424 |
|
2017 |
Shastrula PK, Rice CT, Wang Z, Lieberman PM, Skordalakes E. Structural and functional analysis of an OB-fold in human Ctc1 implicated in telomere maintenance and bone marrow syndromes. Nucleic Acids Research. PMID 29228254 DOI: 10.1093/Nar/Gkx1213 |
0.463 |
|
2017 |
Sakurai M, Shiromoto Y, Ota H, Song C, Kossenkov AV, Wickramasinghe J, Showe LC, Skordalakes E, Tang HY, Speicher DW, Nishikura K. ADAR1 controls apoptosis of stressed cells by inhibiting Staufen1-mediated mRNA decay. Nature Structural & Molecular Biology. PMID 28436945 DOI: 10.1038/Nsmb.3403 |
0.328 |
|
2017 |
Rice C, Shastrula PK, Kossenkov AV, Hills R, Baird DM, Showe LC, Doukov T, Janicki S, Skordalakes E. Structural and functional analysis of the human POT1-TPP1 telomeric complex. Nature Communications. 8: 14928. PMID 28393830 DOI: 10.1038/Ncomms14928 |
0.404 |
|
2017 |
Hoffman H, Rice C, Skordalakes E. Structural Analysis Reveals the Deleterious Effects of Telomerase Mutations in Telomerase-Associated Bone Marrow Failure Syndromes. The Journal of Biological Chemistry. PMID 28154186 DOI: 10.1074/Jbc.M116.771204 |
0.359 |
|
2016 |
Hoffman H, Skordalakes E. Crystallographic Studies of Telomerase. Methods in Enzymology. 573: 403-19. PMID 27372764 DOI: 10.1016/Bs.Mie.2016.04.006 |
0.413 |
|
2016 |
Rice C, Skordalakes E. Structure and function of the telomeric CST complex. Computational and Structural Biotechnology Journal. 14: 161-7. PMID 27239262 DOI: 10.1016/J.Csbj.2016.04.002 |
0.351 |
|
2015 |
Bryan C, Rice C, Hoffman H, Harkisheimer M, Sweeney M, Skordalakes E. Structural Basis of Telomerase Inhibition by the Highly Specific BIBR1532. Structure (London, England : 1993). 23: 1934-42. PMID 26365799 DOI: 10.1016/J.Str.2015.08.006 |
0.435 |
|
2015 |
Greetham M, Skordalakes E, Lydall D, Connolly BA. The Telomere Binding Protein Cdc13 and the Single-Stranded DNA Binding Protein RPA Protect Telomeric DNA from Resection by Exonucleases. Journal of Molecular Biology. 427: 3023-30. PMID 26264873 DOI: 10.1016/J.Jmb.2015.08.002 |
0.407 |
|
2015 |
Iwasaki O, Tanizawa H, Kim KD, Yokoyama Y, Corcoran CJ, Tanaka A, Skordalakes E, Showe LC, Noma K. Interaction between TBP and Condensin Drives the Organization and Faithful Segregation of Mitotic Chromosomes. Molecular Cell. 59: 755-67. PMID 26257282 DOI: 10.1016/J.Molcel.2015.07.007 |
0.312 |
|
2015 |
Panneer Selvam S, De Palma RM, Oaks JJ, Oleinik N, Peterson YK, Stahelin RV, Skordalakes E, Ponnusamy S, Garrett-Mayer E, Smith CD, Ogretmen B. Binding of the sphingolipid S1P to hTERT stabilizes telomerase at the nuclear periphery by allosterically mimicking protein phosphorylation. Science Signaling. 8: ra58. PMID 26082434 DOI: 10.1126/Scisignal.Aaa4998 |
0.358 |
|
2014 |
Peng H, Talebzadeh-Farrooji M, Osborne MJ, Prokop JW, McDonald PC, Karar J, Hou Z, He M, Kebebew E, Orntoft T, Herlyn M, Caton AJ, Fredericks W, Malkowicz B, Paterno CS, ... ... Skordalakes E, et al. LIMD2 is a small LIM-only protein overexpressed in metastatic lesions that regulates cell motility and tumor progression by directly binding to and activating the integrin-linked kinase. Cancer Research. 74: 1390-403. PMID 24590809 DOI: 10.1158/0008-5472.Can-13-1275 |
0.343 |
|
2014 |
Peng H, Farrooji MTZ, Osborne MJ, Prokop JW, McDonald PC, Karar J, Hou Z, He M, Kebebew E, Orntoft T, Herlyn M, Caton AJ, Fredericks W, Malkowicz B, Paterno CS, ... ... Skordalakes E, et al. Abstract 992: LIMD2 is a small LIM-only protein overexpressed in metastatic lesions which regulates cell motility and tumor progression by directly binding to and activating the integrin-linked-kinase Cancer Research. 74: 992-992. DOI: 10.1158/1538-7445.Am2014-992 |
0.366 |
|
2014 |
Bryan C, Rice C, Harkisheimer M, Schultz D, Skordalakes E. Structure of the Human Telomeric Stn1-Ten1 Complex Acta Crystallographica Section A. 70. DOI: 10.1107/S2053273314084125 |
0.395 |
|
2013 |
Harkisheimer M, Mason M, Shuvaeva E, Skordalakes E. A motif in the vertebrate telomerase N-terminal linker of TERT contributes to RNA binding and telomerase activity and processivity. Structure (London, England : 1993). 21: 1870-8. PMID 24055314 DOI: 10.1016/J.Str.2013.08.013 |
0.467 |
|
2013 |
Bryan C, Rice C, Harkisheimer M, Schultz DC, Skordalakes E. Structure of the human telomeric Stn1-Ten1 capping complex. Plos One. 8: e66756. PMID 23826127 DOI: 10.1371/Journal.Pone.0066756 |
0.446 |
|
2013 |
Newhart A, Rafalska-Metcalf IU, Yang T, Joo LM, Powers SL, Kossenkov AV, Lopez-Jones M, Singer RH, Showe LC, Skordalakes E, Janicki SM. Single cell analysis of RNA-mediated histone H3.3 recruitment to a cytomegalovirus promoter-regulated transcription site. The Journal of Biological Chemistry. 288: 19882-99. PMID 23689370 DOI: 10.1074/Jbc.M113.473181 |
0.371 |
|
2013 |
Mason M, Wanat JJ, Harper S, Schultz DC, Speicher DW, Johnson FB, Skordalakes E. Cdc13 OB2 dimerization required for productive Stn1 binding and efficient telomere maintenance. Structure (London, England : 1993). 21: 109-20. PMID 23177925 DOI: 10.1016/J.Str.2012.10.012 |
0.454 |
|
2011 |
Schuller AP, Harkisheimer MJ, Skordalakes E. In vitro reconstitution of the active T. castaneum telomerase. Journal of Visualized Experiments : Jove. e2799. PMID 21775967 DOI: 10.3791/2799 |
0.432 |
|
2011 |
Mason M, Schuller A, Skordalakes E. Telomerase structure function. Current Opinion in Structural Biology. 21: 92-100. PMID 21168327 DOI: 10.1016/J.Sbi.2010.11.005 |
0.441 |
|
2010 |
Mitchell MT, Smith JS, Mason M, Harper S, Speicher DW, Johnson FB, Skordalakes E. Cdc13 N-terminal dimerization, DNA binding, and telomere length regulation. Molecular and Cellular Biology. 30: 5325-34. PMID 20837709 DOI: 10.1128/Mcb.00515-10 |
0.449 |
|
2010 |
Mitchell M, Gillis A, Futahashi M, Fujiwara H, Skordalakes E. Structural basis for telomerase catalytic subunit TERT binding to RNA template and telomeric DNA. Nature Structural & Molecular Biology. 17: 513-8. PMID 20357774 DOI: 10.1038/Nsmb.1777 |
0.42 |
|
2010 |
McCray BA, Skordalakes E, Taylor JP. Disease mutations in Rab7 result in unregulated nucleotide exchange and inappropriate activation. Human Molecular Genetics. 19: 1033-47. PMID 20028791 DOI: 10.1093/Hmg/Ddp567 |
0.348 |
|
2009 |
Wang AY, Schulze JM, Skordalakes E, Gin JW, Berger JM, Rine J, Kobor MS. Asf1-like structure of the conserved Yaf9 YEATS domain and role in H2A.Z deposition and acetylation. Proceedings of the National Academy of Sciences of the United States of America. 106: 21573-8. PMID 19966225 DOI: 10.1073/Pnas.0906539106 |
0.582 |
|
2009 |
Skordalakes E. Telomerase structure paves the way for new cancer therapies. Future Oncology (London, England). 5: 163-7. PMID 19284375 DOI: 10.2217/14796694.5.2.163 |
0.321 |
|
2008 |
Gillis AJ, Schuller AP, Skordalakes E. Structure of the Tribolium castaneum telomerase catalytic subunit TERT. Nature. 455: 633-7. PMID 18758444 DOI: 10.1038/Nature07283 |
0.478 |
|
2008 |
Carlson BL, Ballister ER, Skordalakes E, King DS, Breidenbach MA, Gilmore SA, Berger JM, Bertozzi CR. Function and structure of a prokaryotic formylglycine-generating enzyme. The Journal of Biological Chemistry. 283: 20117-25. PMID 18390551 DOI: 10.1074/Jbc.M800217200 |
0.555 |
|
2007 |
Rouda S, Skordalakes E. Structure of the RNA-binding domain of telomerase: implications for RNA recognition and binding. Structure (London, England : 1993). 15: 1403-12. PMID 17997966 DOI: 10.1016/J.Str.2007.09.007 |
0.448 |
|
2007 |
Young TA, Skordalakes E, Marqusee S. Comparison of proteolytic susceptibility in phosphoglycerate kinases from yeast and E. coli: modulation of conformational ensembles without altering structure or stability. Journal of Molecular Biology. 368: 1438-47. PMID 17397866 DOI: 10.1016/J.Jmb.2007.02.077 |
0.373 |
|
2006 |
Skordalakes E, Berger JM. Structural insights into RNA-dependent ring closure and ATPase activation by the Rho termination factor. Cell. 127: 553-64. PMID 17081977 DOI: 10.1016/J.Cell.2006.08.051 |
0.592 |
|
2005 |
Skordalakes E, Brogan AP, Park BS, Kohn H, Berger JM. Structural mechanism of inhibition of the Rho transcription termination factor by the antibiotic bicyclomycin. Structure (London, England : 1993). 13: 99-109. PMID 15642265 DOI: 10.1016/J.Str.2004.10.013 |
0.589 |
|
2003 |
Daganzo SM, Erzberger JP, Lam WM, Skordalakes E, Zhang R, Franco AA, Brill SJ, Adams PD, Berger JM, Kaufman PD. Structure and function of the conserved core of histone deposition protein Asf1. Current Biology : Cb. 13: 2148-58. PMID 14680630 DOI: 10.1016/J.Cub.2003.11.027 |
0.682 |
|
2003 |
Skordalakes E, Berger JM. Structure of the Rho transcription terminator: mechanism of mRNA recognition and helicase loading. Cell. 114: 135-46. PMID 12859904 DOI: 10.1016/S0092-8674(03)00512-9 |
0.567 |
|
2002 |
Hansen CL, Skordalakes E, Berger JM, Quake SR. A robust and scalable microfluidic metering method that allows protein crystal growth by free interface diffusion. Proceedings of the National Academy of Sciences of the United States of America. 99: 16531-6. PMID 12486223 DOI: 10.1073/Pnas.262485199 |
0.479 |
|
2001 |
Skordalakes E, Dodson GG, Green DS, Goodwin CA, Scully MF, Hudson HR, Kakkar VV, Deadman JJ. Inhibition of human alpha-thrombin by a phosphonate tripeptide proceeds via a metastable pentacoordinated phosphorus intermediate. Journal of Molecular Biology. 311: 549-55. PMID 11493008 DOI: 10.1006/Jmbi.2001.4872 |
0.309 |
|
1999 |
Green D, Skordalakes E, Scully MF, Goodwin C, Merette S, Burd A, Kakkar VV, Deadman J. X-ray crystallographic analyses of human α-thrombin complexed to peptidyl aminophosphonates: Evidence of a binding mechanism Phosphorus, Sulfur and Silicon and Related Elements. 144: 545-548. DOI: 10.1080/10426509908546302 |
0.337 |
|
1998 |
Skordalakes E, Elgendy S, Goodwin CA, Green D, Scully MF, Kakkar VV, Freyssinet JM, Dodson G, Deadman JJ. Bifunctional peptide boronate inhibitors of thrombin: crystallographic analysis of inhibition enhanced by linkage to an exosite 1 binding peptide. Biochemistry. 37: 14420-7. PMID 9772168 DOI: 10.1021/Bi980225A |
0.313 |
|
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