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Hong-Wei Wang - Publications

Affiliations: 
2009-2011 Molecular Biophysics and Biochemistry Yale University, New Haven, CT 
 2010- Life Sciences Tsinghua National University, Beijing, Beijing Shi, China 
Area:
General Biophysics, Biochemistry, Molecular Biology
Website:
http://lsi.zju.edu.cn/en/redir.php?catalog_id=35997&object_id=40990
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76 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Zhou J, Wang A, Song Y, Liu N, Wang J, Li Y, Liang X, Li G, Chu H, Wang HW. Structural insights into the mechanism of GTP initiation of microtubule assembly. Nature Communications. 14: 5980. PMID 37749104 DOI: 10.1038/s41467-023-41615-w  0.356
2020 Jin W, Wang J, Liu CP, Wang HW, Xu RM. Structural Basis for pri-miRNA Recognition by Drosha. Molecular Cell. PMID 32220645 DOI: 10.1016/J.Molcel.2020.02.024  0.33
2020 Liu JJ, Wang HW. Cryo-Electron Microscopy of Endogenous Yeast Exosomes. Methods in Molecular Biology (Clifton, N.J.). 2062: 401-415. PMID 31768987 DOI: 10.1007/978-1-4939-9822-7_19  0.375
2019 Carragher B, Cheng Y, Frost A, Glaeser RM, Lander GC, Nogales E, Wang HW. Current outcomes when optimizing "standard" sample preparation for single-particle cryo-em. Journal of Microscopy. PMID 31553060 DOI: 10.1111/Jmi.12834  0.692
2019 Dai A, Yu L, Wang HW. WHAMM initiates autolysosome tubulation by promoting actin polymerization on autolysosomes. Nature Communications. 10: 3699. PMID 31420534 DOI: 10.1038/S41467-019-11694-9  0.336
2019 Fan X, Wang J, Zhang X, Yang Z, Zhang JC, Zhao L, Peng HL, Lei J, Wang HW. Single particle cryo-EM reconstruction of 52 kDa streptavidin at 3.2 Angstrom resolution. Nature Communications. 10: 2386. PMID 31160591 DOI: 10.1038/S41467-019-10368-W  0.338
2019 Wang J, Hu M, Wang J, Qi J, Han Z, Wang G, Qi Y, Wang HW, Zhou JM, Chai J. Reconstitution and structure of a plant NLR resistosome conferring immunity. Science (New York, N.Y.). 364. PMID 30948527 DOI: 10.1126/Science.Aav5870  0.364
2019 Liu N, Zhang J, Chen Y, Liu C, Zhang X, Xu K, Wen J, Luo Z, Chen S, Gao P, Jia K, Liu Z, Peng H, Wang H. Bioactive functionalized monolayer graphene for high resolution cryo-EM. Journal of the American Chemical Society. PMID 30724081 DOI: 10.1021/Jacs.8B13038  0.341
2018 Chen X, Liu M, Tian Y, Li J, Qi Y, Zhao D, Wu Z, Huang M, Wong CCL, Wang HW, Wang J, Yang H, Xu Y. Cryo-EM structure of human mTOR complex 2. Cell Research. PMID 29567957 DOI: 10.1038/S41422-018-0029-3  0.424
2018 Zhao L, Xu J, Zhao W, Sung P, Wang HW. Determining the RAD51-DNA Nucleoprotein Filament Structure and Function by Cryo-Electron Microscopy. Methods in Enzymology. 600: 179-199. PMID 29458758 DOI: 10.1016/Bs.Mie.2017.12.002  0.318
2018 Mei K, Li Y, Wang S, Shao G, Wang J, Ding Y, Luo G, Yue P, Liu JJ, Wang X, Dong MQ, Wang HW, Guo W. Cryo-EM structure of the exocyst complex. Nature Structural & Molecular Biology. PMID 29335562 DOI: 10.1038/s41594-017-0016-2  0.4
2018 Liu Z, Wang J, Cheng H, Ke X, Sun L, Zhang QC, Wang H. Cryo-EM Structure of Human Dicer and Its Complexes with a Pre-miRNA Substrate Cell. 173: 1549-1550. DOI: 10.2210/Pdb5Zam/Pdb  0.403
2017 Rao Q, Liu M, Tian Y, Wu Z, Hao Y, Song L, Qin Z, Ding C, Wang HW, Wang J, Xu Y. Cryo-EM structure of human ATR-ATRIP complex. Cell Research. PMID 29271416 DOI: 10.1038/cr.2017.158  0.423
2017 Guan Z, Cai T, Liu Z, Dou Y, Hu X, Zhang P, Sun X, Li H, Kuang Y, Zhai Q, Ruan H, Li X, Li Z, Zhu Q, Mai J, ... Wang HW, et al. Origin of the Reflectin Gene and Hierarchical Assembly of Its Protein. Current Biology : Cb. PMID 28889973 DOI: 10.1016/J.Cub.2017.07.061  0.393
2017 Zheng JX, Li Y, Ding YH, Liu JJ, Zhang MJ, Dong MQ, Wang HW, Yu L. Architecture of the ATG2B-WDR45 complex and an aromatic Y/HF motif crucial for complex formation. Autophagy. 0. PMID 28820312 DOI: 10.1080/15548627.2017.1359381  0.41
2017 Zhou Q, Zhou N, Wang HW. Particle segmentation algorithm for flexible single particle reconstruction. Biophysics Reports. 3: 43-55. PMID 28782000 DOI: 10.1007/S41048-017-0038-7  0.301
2017 Ma M, Liu JJ, Li Y, Huang Y, Ta N, Chen Y, Fu H, Ye MD, Ding Y, Huang W, Wang J, Dong MQ, Yu L, Wang HW. Cryo-EM structure and biochemical analysis reveal the basis of the functional difference between human PI3KC3-C1 and -C2. Cell Research. PMID 28731030 DOI: 10.1038/Cr.2017.94  0.318
2017 Sun S, Li L, Yang F, Wang X, Fan F, Yang M, Chen C, Li X, Wang HW, Sui SF. Cryo-EM structures of the ATP-bound Vps4(E233Q) hexamer and its complex with Vta1 at near-atomic resolution. Nature Communications. 8: 16064. PMID 28714467 DOI: 10.1038/Ncomms16064  0.466
2017 Liu T, Dai A, Cao Y, Zhang R, Dong MQ, Wang HW. Structural insights of WHAMM's interaction with microtubules by cryo-EM. Journal of Molecular Biology. PMID 28351611 DOI: 10.1016/J.Jmb.2017.03.022  0.455
2016 Yang H, Wang J, Liu M, Chen X, Huang M, Tan D, Dong MQ, Wong CC, Wang J, Xu Y, Wang HW. 4.4 Å Resolution Cryo-EM structure of human mTOR Complex 1. Protein & Cell. PMID 27909983 DOI: 10.1007/S13238-016-0346-6  0.401
2016 Agrawal RK, Wang HW, Belfort M. Forks in the tracks: group II introns, spliceosomes, telomeres and beyond. Rna Biology. 0. PMID 27726484 DOI: 10.1080/15476286.2016.1244595  0.349
2016 Wang HW, Wang JW. How Cryo-Electron Microscopy and X-ray Crystallography Complement Each Other. Protein Science : a Publication of the Protein Society. PMID 27543495 DOI: 10.1002/Pro.3022  0.316
2016 Liu JJ, Niu CY, Wu Y, Tan D, Wang Y, Ye MD, Liu Y, Zhao W, Zhou K, Liu QS, Dai J, Yang X, Dong MQ, Huang N, Wang HW. CryoEM structure of yeast cytoplasmic exosome complex. Cell Research. PMID 27174052 DOI: 10.1038/Cr.2016.56  0.408
2016 Qu G, Kaushal PS, Wang J, Shigematsu H, Piazza CL, Agrawal RK, Belfort M, Wang HW. Structure of a group II intron in complex with its reverse transcriptase. Nature Structural & Molecular Biology. PMID 27136327 DOI: 10.1038/Nsmb.3220  0.402
2016 Tan D, Li Q, Zhang MJ, Liu C, Ma C, Zhang P, Ding YH, Fan SB, Tao L, Yang B, Li X, Ma S, Liu J, Feng B, Liu X, Wang HW, et al. Trifunctional cross-linker for mapping protein-protein interaction networks and comparing protein conformational states. Elife. 5. PMID 26952210 DOI: 10.7554/Elife.12509  0.318
2015 Jia N, Liu N, Cheng W, Jiang YL, Sun H, Chen LL, Peng J, Zhang Y, Ding YH, Zhang ZH, Wang X, Cai G, Wang J, Dong MQ, Zhang Z, ... Wang HW, et al. Structural basis for receptor recognition and pore formation of a zebrafish aerolysin-like protein. Embo Reports. PMID 26711430 DOI: 10.15252/Embr.201540851  0.371
2015 Wang J, Chai J, Wang H. Structure of the mouse toll-like receptor 13 ectodomain in complex with a conserved sequence from bacterial 23S ribosomal RNA. The Febs Journal. PMID 26676765 DOI: 10.1111/Febs.13628  0.36
2015 He Q, Wang F, Liu S, Zhu D, Cong H, Gao F, Li B, Wang H, Lin Z, Liao J, Gu L. Structural and Biochemical Insight into the Mechanism of Rv2837c from Mycobacterium tuberculosis as a C-di-NMP Phosphodiesterase. The Journal of Biological Chemistry. PMID 26668313 DOI: 10.1074/Jbc.M115.699801  0.305
2015 Wang J, Wang W, Song W, Han Z, Zhang H, Chai J, Wang H, Wang J. An improved method for phasing crystal structures with low non-crystallographic symmetry using cryo-electron microscopy data. Protein & Cell. PMID 26507843 DOI: 10.1007/S13238-015-0219-4  0.312
2015 Tomko RJ, Taylor DW, Chen ZA, Wang HW, Rappsilber J, Hochstrasser M. A Single α Helix Drives Extensive Remodeling of the Proteasome Lid and Completion of Regulatory Particle Assembly. Cell. 163: 432-44. PMID 26451487 DOI: 10.1016/J.Cell.2015.09.022  0.642
2015 Song W, Wang J, Han Z, Zhang Y, Zhang H, Wang W, Chang J, Xia B, Fan S, Zhang D, Wang J, Wang HW, Chai J. Structural basis for specific recognition of single-stranded RNA by Toll-like receptor 13. Nature Structural & Molecular Biology. PMID 26323037 DOI: 10.1038/Nsmb.3080  0.311
2015 Qu G, Dong X, Lyn Piazza C, Wang J, Wang H, Belfort M. 83 Structural dynamics of a mobile group II intron ribonucleoprotein complex. Journal of Biomolecular Structure & Dynamics. 33: 54. PMID 26103295 DOI: 10.1080/07391102.2015.1032700  0.314
2015 Tagare HD, Kucukelbir A, Sigworth FJ, Wang H, Rao M. Directly reconstructing principal components of heterogeneous particles from cryo-EM images. Journal of Structural Biology. PMID 26049077 DOI: 10.1016/J.Jsb.2015.05.007  0.32
2015 Zhou Q, Huang X, Sun S, Li X, Wang HW, Sui SF. Cryo-EM structure of SNAP-SNARE assembly in 20S particle. Cell Research. 25: 551-60. PMID 25906996 DOI: 10.1038/Cr.2015.47  0.373
2015 Wang H. Cryo-electron microscopy for structural biology: current status and future perspectives. Science China. Life Sciences. PMID 25894285 DOI: 10.1007/S11427-015-4851-2  0.316
2015 Chang S, Sun D, Liang H, Wang J, Li J, Guo L, Wang X, Guan C, Boruah BM, Yuan L, Feng F, Yang M, Wang L, Wang Y, Wojdyla J, ... Wang HW, et al. Cryo-EM structure of influenza virus RNA polymerase complex at 4.3 Å resolution. Molecular Cell. 57: 925-35. PMID 25620561 DOI: 10.1016/J.Molcel.2014.12.031  0.393
2015 Liu Z, Wang J, Li G, Wang HW. Structure of precursor microRNA's terminal loop regulates human Dicer's dicing activity by switching DExH/D domain. Protein & Cell. 6: 185-93. PMID 25549615 DOI: 10.1007/S13238-014-0124-2  0.333
2014 Liu JJ, Bratkowski MA, Liu X, Niu CY, Ke A, Wang HW. Visualization of distinct substrate-recruitment pathways in the yeast exosome by EM. Nature Structural & Molecular Biology. 21: 95-102. PMID 24336220 DOI: 10.1038/Nsmb.2736  0.362
2014 Yip WSV, Shigematsu H, Taylor DW, Wang HW, Baserga SJ. Cryo-electron microscopic study of the enzymatic mechanism of the RNA 2'-O-methyltransferase Box C\D sRNP Microscopy and Microanalysis. 20: 1284-1285. DOI: 10.1017/S1431927614008150  0.507
2013 Yin P, Li Q, Yan C, Liu Y, Liu J, Yu F, Wang Z, Long J, He J, Wang HW, Wang J, Zhu JK, Shi Y, Yan N. Structural basis for the modular recognition of single-stranded RNA by PPR proteins. Nature. 504: 168-71. PMID 24162847 DOI: 10.1038/Nature12651  0.352
2013 Wolin SL, Belair C, Boccitto M, Chen X, Sim S, Taylor DW, Wang HW. Non-coding Y RNAs as tethers and gates: Insights from bacteria. Rna Biology. 10: 1602-8. PMID 24036917 DOI: 10.4161/Rna.26166  0.571
2013 Li Y, Hsin J, Zhao L, Cheng Y, Shang W, Huang KC, Wang HW, Ye S. FtsZ protofilaments use a hinge-opening mechanism for constrictive force generation. Science (New York, N.Y.). 341: 392-5. PMID 23888039 DOI: 10.1126/Science.1239248  0.398
2013 Taylor DW, Ma E, Shigematsu H, Cianfrocco MA, Noland CL, Nagayama K, Nogales E, Doudna JA, Wang HW. Substrate-specific structural rearrangements of human Dicer. Nature Structural & Molecular Biology. 20: 662-70. PMID 23624860 DOI: 10.1038/Nsmb.2564  0.76
2013 Chen X, Taylor DW, Fowler CC, Galan JE, Wang HW, Wolin SL. An RNA degradation machine sculpted by Ro autoantigen and noncoding RNA. Cell. 153: 166-77. PMID 23540697 DOI: 10.1016/J.Cell.2013.02.037  0.577
2013 Yip W, Shigematsu H, Taylor D, Wang H, Baserga S. Structural Elucidation of Archaeal Box C/D sRNP by Cryo-Electron Microscopy Microscopy and Microanalysis. 19: 126-127. DOI: 10.1017/S1431927613002626  0.498
2012 Shen QT, Hsiue PP, Sindelar CV, Welch MD, Campellone KG, Wang HW. Structural insights into WHAMM-mediated cytoskeletal coordination during membrane remodeling. The Journal of Cell Biology. 199: 111-24. PMID 23027905 DOI: 10.1083/Jcb.201204010  0.396
2012 Li B, Li N, Wang F, Guo L, Huang Y, Liu X, Wei T, Zhu D, Liu C, Pan H, Xu S, Wang HW, Gu L. Structural insight of a concentration-dependent mechanism by which YdiV inhibits Escherichia coli flagellum biogenesis and motility. Nucleic Acids Research. 40: 11073-85. PMID 23002140 DOI: 10.1093/Nar/Gks869  0.379
2012 Nam KH, Haitjema C, Liu X, Ding F, Wang H, DeLisa MP, Ke A. Cas5d protein processes pre-crRNA and assembles into a cascade-like interference complex in subtype I-C/Dvulg CRISPR-Cas system. Structure (London, England : 1993). 20: 1574-84. PMID 22841292 DOI: 10.1016/J.Str.2012.06.016  0.402
2012 Bower-Phipps KR, Taylor DW, Wang HW, Baserga SJ. The box C/D sRNP dimeric architecture is conserved across domain Archaea. Rna (New York, N.Y.). 18: 1527-40. PMID 22753779 DOI: 10.1261/Rna.033134.112  0.591
2012 Zhou K, Kanai R, Lee P, Wang HW, Modis Y. Toll-like receptor 5 forms asymmetric dimers in the absence of flagellin. Journal of Structural Biology. 177: 402-9. PMID 22173220 DOI: 10.1016/J.Jsb.2011.12.002  0.35
2011 Chandramouli P, Hernandez-Lopez R, Wang HW, Leschziner AE. Validation of the orthogonal tilt reconstruction method with a biological test sample. Journal of Structural Biology. 175: 85-96. PMID 21536134 DOI: 10.1016/J.Jsb.2011.04.012  0.66
2011 Liu X, Wang H. Single particle electron microscopy reconstruction of the exosome complex using the random conical tilt method. Journal of Visualized Experiments. PMID 21490573 DOI: 10.3791/2574  0.348
2011 Wu X, Shen QT, Oristian DS, Lu CP, Zheng Q, Wang HW, Fuchs E. Skin stem cells orchestrate directional migration by regulating microtubule-ACF7 connections through GSK3β. Cell. 144: 341-52. PMID 21295697 DOI: 10.1016/J.Cell.2010.12.033  0.328
2011 Ramey VH, Wang HW, Nakajima Y, Wong A, Liu J, Drubin D, Barnes G, Nogales E. The Dam1 ring binds to the E-hook of tubulin and diffuses along the microtubule. Molecular Biology of the Cell. 22: 457-66. PMID 21169562 DOI: 10.1091/Mbc.E10-10-0841  0.788
2011 Shen Q, Campellone KG, Sindelar CV, Welch M, Wang H. Structural Basis of WHAMM to Regulate Golgi Membrane Transportation via Interacting with Both Microtubules and Membranes Biophysical Journal. 100: 49a. DOI: 10.1016/J.Bpj.2010.12.466  0.429
2010 Yang H, Wang J, Jia X, McNatt MW, Zang T, Pan B, Meng W, Wang HW, Bieniasz PD, Xiong Y. Structural insight into the mechanisms of enveloped virus tethering by tetherin. Proceedings of the National Academy of Sciences of the United States of America. 107: 18428-32. PMID 20940320 DOI: 10.1073/Pnas.1011485107  0.372
2010 Nogales E, Ramey VH, Wang HW. Cryo-EM studies of microtubule structural intermediates and kinetochore-microtubule interactions. Methods in Cell Biology. 95: 129-56. PMID 20466133 DOI: 10.1016/S0091-679X(10)95008-5  0.799
2009 Wang HW, Noland C, Siridechadilok B, Taylor DW, Ma E, Felderer K, Doudna JA, Nogales E. Structural insights into RNA processing by the human RISC-loading complex. Nature Structural & Molecular Biology. 16: 1148-53. PMID 19820710 DOI: 10.1038/Nsmb.1673  0.752
2009 Wu Z, Wang HW, Mu W, Ouyang Z, Nogales E, Xing J. Simulations of tubulin sheet polymers as possible structural intermediates in microtubule assembly. Plos One. 4: e7291. PMID 19806219 DOI: 10.1371/Journal.Pone.0007291  0.704
2009 Ramey VH, Wang HW, Nogales E. Ab initio reconstruction of helical samples with heterogeneity, disorder and coexisting symmetries. Journal of Structural Biology. 167: 97-105. PMID 19447181 DOI: 10.1016/J.Jsb.2009.05.002  0.785
2008 Wang HW, Long S, Ciferri C, Westermann S, Drubin D, Barnes G, Nogales E. Architecture and flexibility of the yeast Ndc80 kinetochore complex. Journal of Molecular Biology. 383: 894-903. PMID 18793650 DOI: 10.1016/J.Jmb.2008.08.077  0.709
2007 Wang HW, Wang J, Ding F, Callahan K, Bratkowski MA, Butler JS, Nogales E, Ke A. Architecture of the yeast Rrp44 exosome complex suggests routes of RNA recruitment for 3' end processing. Proceedings of the National Academy of Sciences of the United States of America. 104: 16844-9. PMID 17942686 DOI: 10.1073/Pnas.0705526104  0.677
2007 Wang HW, Ramey VH, Westermann S, Leschziner AE, Welburn JP, Nakajima Y, Drubin DG, Barnes G, Nogales E. Architecture of the Dam1 kinetochore ring complex and implications for microtubule-driven assembly and force-coupling mechanisms. Nature Structural & Molecular Biology. 14: 721-6. PMID 17643123 DOI: 10.1038/Nsmb1274  0.781
2006 Nogales E, Wang HW. Structural mechanisms underlying nucleotide-dependent self-assembly of tubulin and its relatives. Current Opinion in Structural Biology. 16: 221-9. PMID 16549346 DOI: 10.1016/J.Sbi.2006.03.005  0.71
2006 Nogales E, Wang HW. Structural intermediates in microtubule assembly and disassembly: how and why? Current Opinion in Cell Biology. 18: 179-84. PMID 16495041 DOI: 10.1016/J.Ceb.2006.02.009  0.699
2006 Westermann S, Wang HW, Avila-Sakar A, Drubin DG, Nogales E, Barnes G. The Dam1 kinetochore ring complex moves processively on depolymerizing microtubule ends. Nature. 440: 565-9. PMID 16415853 DOI: 10.1038/Nature04409  0.714
2005 Wang HW, Long S, Finley KR, Nogales E. Assembly of GMPCPP-bound tubulin into helical ribbons and tubes and effect of colchicine. Cell Cycle (Georgetown, Tex.). 4: 1157-60. PMID 16123589 DOI: 10.4161/Cc.4.9.2042  0.695
2005 Wang HW, Nogales E. Nucleotide-dependent bending flexibility of tubulin regulates microtubule assembly. Nature. 435: 911-5. PMID 15959508 DOI: 10.1038/Nature03606  0.708
2005 Westermann S, Avila-Sakar A, Wang HW, Niederstrasser H, Wong J, Drubin DG, Nogales E, Barnes G. Formation of a dynamic kinetochore- microtubule interface through assembly of the Dam1 ring complex. Molecular Cell. 17: 277-90. PMID 15664196 DOI: 10.1016/J.Molcel.2004.12.019  0.808
2005 Wang HW, Nogales E. An iterative Fourier-Bessel algorithm for reconstruction of helical structures with severe Bessel overlap. Journal of Structural Biology. 149: 65-78. PMID 15629658 DOI: 10.1016/J.Jsb.2004.08.006  0.605
2003 Wu Y, Wang HW, Ji SR, Sui SF. Two-dimensional crystallization of rabbit C-reactive protein monomeric subunits. Acta Crystallographica. Section D, Biological Crystallography. 59: 922-6. PMID 12777813 DOI: 10.1107/S0907444903004414  0.316
2003 Nogales E, Wang HW, Niederstrasser H. Tubulin rings: which way do they curve? Current Opinion in Structural Biology. 13: 256-61. PMID 12727521 DOI: 10.1016/S0959-440X(03)00029-0  0.79
2003 Wang HW, Chen Y, Yang H, Chen X, Duan MX, Tai PC, Sui SF. Ring-like pore structures of SecA: implication for bacterial protein-conducting channels. Proceedings of the National Academy of Sciences of the United States of America. 100: 4221-6. PMID 12642659 DOI: 10.1073/Pnas.0737415100  0.362
2002 Wang H, Wu Y, Chen Y, Sui S. Polymorphism of structural forms of C-reactive protein. International Journal of Molecular Medicine. 9: 665-671. DOI: 10.3892/Ijmm.9.6.665  0.378
2001 Wang H, Sui S. Dissociation and subunit rearrangement of membrane-bound human C-reactive proteins. Biochemical and Biophysical Research Communications. 288: 75-79. PMID 11594754 DOI: 10.1006/Bbrc.2001.5733  0.323
2001 Wang H, Sui S. Two-dimensional assembly of pentameric rabbit C-reactive proteins on lipid monolayers. Journal of Structural Biology. 134: 46-55. PMID 11469876 DOI: 10.1006/Jsbi.2001.4364  0.3
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