LuZhe Sun - Publications

Affiliations: 
University of Kentucky, Lexington, KY 
Area:
Pharmacology, Molecular Biology

106 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Shropshire DB, Acosta FM, Fang K, Benavides J, Sun LZ, Jin VX, Jiang JX. Association of adenosine signaling gene signature with estrogen receptor-positive breast and prostate cancer bone metastasis. Frontiers in Medicine. 9: 965429. PMID 36186774 DOI: 10.3389/fmed.2022.965429  0.331
2022 Lin M, Zhu H, Shen Q, Sun LZ, Zhu X. GLI3 and androgen receptor are mutually dependent for their malignancy-promoting activity in ovarian and breast cancer cells. Cellular Signalling. 92: 110278. PMID 35134468 DOI: 10.1016/j.cellsig.2022.110278  0.375
2021 Tian Y, Riquelme MA, Tu C, Quan Y, Liu X, Sun LZ, Jiang JX. Osteocytic Connexin Hemichannels Modulate Oxidative Bone Microenvironment and Breast Cancer Growth. Cancers. 13. PMID 34944962 DOI: 10.3390/cancers13246343  0.308
2020 Cadena M, DeLuna F, Baryeh K, Sun LZ, Ye JY. Prostate Cancer Epithelial Mesenchymal Transition by TGF-β1 exposure monitored with a Photonic Crystal Biosensor. Proceedings of Spie--the International Society For Optical Engineering. 11251. PMID 32632340 DOI: 10.1117/12.2544113  0.378
2020 Xia L, Bouamar H, Gu X, Zeballos C, Qin T, Wang B, Zhou Y, Wang Y, Yang J, Zhu H, Zhang W, Houghton PJ, Sun LZ. Gli2 mediates the development of castration‑resistant prostate cancer. International Journal of Oncology. PMID 32319599 DOI: 10.3892/Ijo.2020.5044  0.431
2019 Zhou L, Ye M, Xue F, Lu E, Sun LZ, Zhu X. Effects of dynein light chain Tctex-type 3 on the biological behavior of ovarian cancer. Cancer Management and Research. 11: 5925-5938. PMID 31308737 DOI: 10.2147/Cmar.S205158  0.301
2019 Chen G, Ding XF, Bouamar H, Pressley K, Sun LZ. Everolimusinduces G1 cell cycle arrest through autophagy-mediated protein degradation of cyclin D1 in breast cancer cells. American Journal of Physiology. Cell Physiology. PMID 31116586 DOI: 10.1152/Ajpcell.00390.2018  0.358
2019 Broome LE, Wang B, Zhao M, Yang J, Bouamar H, Cserhati M, Sun L. Abstract 181: Prolyl-4-hydroxylase α subunit 3 promotes renal cancer progression and metastasis Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-181  0.336
2018 DeLuna F, Ding X, Sagredo I, Bustamante G, Sun LZ, Ye JY. Label-free prostate cancer cell detection via photonic-crystal biosensor. Proceedings of Spie--the International Society For Optical Engineering. 10504. PMID 32528210 DOI: 10.1117/12.2288019  0.304
2018 Chen G, Bouamar H, Sun LZ. Isolation, Culture, and Differentiation of Mammary Epithelial Stem/Progenitor Cells from Fresh or Ex Vivo Cultured Human Breast Tissue. Current Protocols in Cell Biology. e65. PMID 30265440 DOI: 10.1002/Cpcb.65  0.338
2018 Zhu H, Xia L, Shen Q, Zhao M, Gu X, Bouamar H, Wang B, Sun LZ, Zhu X. Differential effects of GLI2 and GLI3 in regulating cervical cancer malignancy in vitro and in vivo. Laboratory Investigation; a Journal of Technical Methods and Pathology. PMID 29967343 DOI: 10.1038/s41374-018-0089-5  0.331
2018 Zhu H, Gu X, Xia L, Zhou Y, Bouamar H, Yang J, Ding X, Zwieb C, Zhang J, P Hinck A, Sun L, Zhu X. A Novel TGF-β Trap Blocks Chemotherapeutics-Induced TGF-β1 Signaling and Enhances Their Anticancer Activity in Gynecological Cancers. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 29549162 DOI: 10.1158/1078-0432.Ccr-17-3112  0.426
2018 Shen Z, Li S, Sheng B, Shen Q, Sun LZ, Zhu H, Zhu X. The role of atorvastatin in suppressing tumor growth of uterine fibroids. Journal of Translational Medicine. 16: 53. PMID 29523174 DOI: 10.1186/S12967-018-1430-X  0.366
2018 Wang B, Gu X, Zhu H, Sun L. Abstract 36: Novel age-related tumor promoting and inhibiting genes in breast cancer Cancer Research. 78: 36-36. DOI: 10.1158/1538-7445.Am2018-36  0.436
2018 Zeballos C, Bouamar H, Zheng G, Gu X, Chen Y, Cigarroa FG, Sun L. Abstract 2424: Hepatocellular carcinoma in the South Texas Latino population: Implications of STEAP2 Cancer Research. 78: 2424-2424. DOI: 10.1158/1538-7445.Am2018-2424  0.342
2017 Horning AM, Wang Y, Lin CK, Louie AD, Jadhav RR, Hung CN, Wang CM, Lin CL, Kirma NB, Liss MA, Kumar AP, Sun L, Liu Z, Chao WT, Wang Q, et al. Single-cell RNA-seq reveals a subpopulation of prostate cancer cells with enhanced cell cycle-related transcription and attenuated androgen response. Cancer Research. PMID 29233929 DOI: 10.1158/0008-5472.Can-17-1924  0.347
2017 Qin T, Barron L, Xia L, Huang H, Villarreal MM, Zwaagstra J, Collins C, Yang J, Zwieb C, Kodali R, Hinck CS, Kim SK, Reddick RL, Shu C, O'Connor-McCourt MD, ... ... Sun LZ, et al. Correction: A novel highly potent trivalent TGF-β receptor trap inhibits early-stage tumorigenesis and tumor cell invasion in murine Pten-deficient prostate glands. Oncotarget. 8: 57905. PMID 28915722 DOI: 10.18632/Oncotarget.20370  0.42
2017 Gu X, Zhu H, Sun L. Abstract P1-08-08: Identification of tumor-promoting and tumor-inhibiting genes with age dependent expression in breast cancer patients Cancer Research. 77. DOI: 10.1158/1538-7445.Sabcs16-P1-08-08  0.398
2017 Gu X, Bouamar H, Pressley K, Sun L. Abstract 914: Age-associated neoplastic transformation of mammary stem cells Cancer Research. 77: 914-914. DOI: 10.1158/1538-7445.Am2017-914  0.439
2016 Qin T, Barron L, Xia L, Huang H, Villarreal MM, Zwaagstra J, Collins C, Yang J, Zwieb C, Kodali R, Hinck CS, Kyung Kim S, Reddick RL, Shu C, O'Connor-McCourt MD, ... ... Sun LZ, et al. A novel highly potent trivalent TGF-β receptor trap inhibits early-stage tumorigenesis and tumor cell invasion in murine Pten-deficient prostate glands. Oncotarget. PMID 27863384 DOI: 10.18632/oncotarget.13343  0.35
2016 Dong Q, Gao H, Shi Y, Zhang F, Gu X, Wu A, Wang D, Chen Y, Bandyopadhyay A, Yeh IT, Daniel BJ, Chen Y, Zou Y, Rebel VL, Walter CA, ... ... Sun LZ, et al. Aging is associated with an expansion of CD49f(hi) mammary stem cells that show a decline in function and increased transformation potential. Aging. PMID 27852980 DOI: 10.18632/aging.101082  0.304
2016 Huang G, Osmulski PA, Bouamar H, Mahalingam D, Lin CL, Liss MA, Pratap Kumar A, Chen CL, Thompson IM, Sun LZ, Gaczynska ME, Huang TH. TGF-β signal rewiring sustains epithelial-mesenchymal transition of circulating tumor cells in prostate cancer xenograft hosts. Oncotarget. PMID 27780930 DOI: 10.18632/oncotarget.12808  0.386
2016 Liu J, Akanuma N, Liu C, Naji A, Halff GA, Washburn WK, Sun L, Wang P. TGF-β1 promotes acinar to ductal metaplasia of human pancreatic acinar cells. Scientific Reports. 6: 30904. PMID 27485764 DOI: 10.1038/Srep30904  0.401
2016 Liu Z, Wang L, Yang J, Bandyopadhyay A, Kaklamani V, Wang S, Sun LZ. Estrogen receptor alpha inhibits senescence-like phenotype and facilitates transformation induced by oncogenic ras in human mammary epithelial cells. Oncotarget. PMID 27259243 DOI: 10.18632/oncotarget.9772  0.391
2016 Zhou JZ, Riquelme MA, Gu S, Kar R, Gao X, Sun L, Jiang JX. Osteocytic connexin hemichannels suppress breast cancer growth and bone metastasis. Oncogene. PMID 27041582 DOI: 10.1038/Onc.2016.101  0.467
2016 Zhu H, Luo H, Shen Z, Hu X, Sun L, Zhu X. Transforming growth factor-β1 in carcinogenesis, progression, and therapy in cervical cancer. Tumour Biology : the Journal of the International Society For Oncodevelopmental Biology and Medicine. PMID 27010470 DOI: 10.1007/S13277-016-5028-8  0.436
2016 Gao H, Dong Q, Chen Y, Zhang F, Wu A, Shi Y, Bandyopadhyay A, Daniel BJ, Huang C, Sun LZ. Murine mammary stem/progenitor cell isolation: Different method matters? Springerplus. 5: 140. PMID 26933638 DOI: 10.1186/S40064-016-1787-3  0.354
2016 Bouamar H, Zhang F, Gu X, Dong Q, Sun L. Abstract P6-07-02: Bisphenol A treatment induces hyperplasia in primary and stem cell-generated mammary glands from pregnant mice Cancer Research. 78: 3308-3308. DOI: 10.1158/1538-7445.Sabcs17-P6-07-02  0.4
2016 Xia L, Qin T, Sun L. Abstract 5173: Role of Gli2 in mediating the progression of prostate cancer to CRPC Cancer Research. 76: 5173-5173. DOI: 10.1158/1538-7445.Am2016-5173  0.464
2016 Zhu H, Yang J, Gu X, Sun L. Abstract 4127: Blockade of TGFβ signaling enhances anticancer effect of chemotherapeutics in gynecologic cancers Cancer Research. 76: 4127-4127. DOI: 10.1158/1538-7445.Am2016-4127  0.454
2015 Mishra S, Tai Q, Gu X, Schmitz J, Poullard A, Fajardo RJ, Mahalingam D, Chen X, Zhu X, Sun LZ. Estrogen and estrogen receptor alpha promotes malignancy and osteoblastic tumorigenesis in prostate cancer. Oncotarget. PMID 26575018 DOI: 10.18632/Oncotarget.6317  0.333
2015 Mukhopadhyay KD, Liu Z, Bandyopadhyay A, Kirma NB, Tekmal RR, Wang S, Sun LZ. Aromatase expression increases the survival and malignancy of estrogen receptor positive breast cancer cells. Plos One. 10: e0121136. PMID 25837259 DOI: 10.1371/journal.pone.0121136  0.351
2015 Liu Z, Hou J, Ren L, He J, Sun B, Sun LZ, Wang S. Protein tyrosine phosphatase receptor type O expression in the tumor niche correlates with reduced tumor growth, angiogenesis, circulating tumor cells and metastasis of breast cancer. Oncology Reports. 33: 1908-14. PMID 25646811 DOI: 10.3892/or.2015.3772  0.346
2015 Zhou JZ, Riquelme MA, Gao X, Ellies LG, Sun LZ, Jiang JX. Differential impact of adenosine nucleotides released by osteocytes on breast cancer growth and bone metastasis. Oncogene. 34: 1831-42. PMID 24837364 DOI: 10.1038/Onc.2014.113  0.454
2015 Gu X, Gao H, Wang D, Bandyopadhyay A, Dong Q, Sun L. Abstract P1-06-06: Meta-analysis reveal novel mechanism of bisphenol A effect on mammary gland Cancer Research. 75. DOI: 10.1158/1538-7445.Sabcs14-P1-06-06  0.463
2014 Mishra S, Lin CL, Huang TH, Bouamar H, Sun LZ. MicroRNA-21 inhibits p57Kip2 expression in prostate cancer. Molecular Cancer. 13: 212. PMID 25216674 DOI: 10.1186/1476-4598-13-212  0.3
2014 Wang D, Gao H, Bandyopadhyay A, Wu A, Yeh IT, Chen Y, Zou Y, Huang C, Walter CA, Dong Q, Sun LZ. Pubertal bisphenol A exposure alters murine mammary stem cell function leading to early neoplasia in regenerated glands. Cancer Prevention Research (Philadelphia, Pa.). 7: 445-55. PMID 24520039 DOI: 10.1158/1940-6207.Capr-13-0260  0.35
2014 Biswas T, Gu X, Yang J, Ellies LG, Sun LZ. Attenuation of TGF-β signaling supports tumor progression of a mesenchymal-like mammary tumor cell line in a syngeneic murine model Cancer Letters. 346: 129-138. PMID 24368187 DOI: 10.1016/j.canlet.2013.12.018  0.371
2014 Roy SS, Gonugunta VK, Bandyopadhyay A, Rao MK, Goodall GJ, Sun LZ, Tekmal RR, Vadlamudi RK. Significance of PELP1/HDAC2/miR-200 regulatory network in EMT and metastasis of breast cancer. Oncogene. 33: 3707-16. PMID 23975430 DOI: 10.1038/Onc.2013.332  0.333
2013 Mishra S, Deng JJ, Gowda PS, Rao MK, Lin CL, Chen CL, Huang T, Sun LZ. Androgen receptor and microRNA-21 axis downregulates transforming growth factor beta receptor II (TGFBR2) expression in prostate cancer. Oncogene. 33: 4097-106. PMID 24037531 DOI: 10.1038/Onc.2013.374  0.413
2013 Gowda PS, Deng JD, Mishra S, Bandyopadhyay A, Liang S, Lin S, Mahalingam D, Sun LZ. Inhibition of hedgehog and androgen receptor signaling pathways produced synergistic suppression of castration-resistant prostate cancer progression. Molecular Cancer Research : McR. 11: 1448-61. PMID 23989930 DOI: 10.1158/1541-7786.Mcr-13-0278  0.428
2013 Dong Q, Wang D, Bandyopadhyay A, Gao H, Gorena KM, Hildreth K, Rebel VI, Walter CA, Huang C, Sun LZ. Mammospheres from murine mammary stem cell-enriched basal cells: clonal characteristics and repopulating potential. Stem Cell Research. 10: 396-404. PMID 23466563 DOI: 10.1016/J.Scr.2013.01.007  0.357
2013 Chen CL, Mahalingam D, Osmulski P, Jadhav RR, Wang CM, Leach RJ, Chang TC, Weitman SD, Kumar AP, Sun L, Gaczynska ME, Thompson IM, Huang TH. Single-cell analysis of circulating tumor cells identifies cumulative expression patterns of EMT-related genes in metastatic prostate cancer. The Prostate. 73: 813-26. PMID 23280481 DOI: 10.1002/Pros.22625  0.431
2013 Sun L, Bandyopadhyay A, Dong Q, Gao H, Gu X, Wang D, Wu A, Huang C. Abstract B035: Preneoplastic transformation of murine mammary stem cells by aging and inhibition by rapamycin Molecular Cancer Research. 11. DOI: 10.1158/1557-3125.Advbc-B035  0.409
2013 gowda p, Deng J, Mishra S, Sun L. Abstract 2126: Inhibition of hedgehog and androgen receptor signaling pathways produced synergistic suppression of androgen independent prostate cancer progression. Cancer Research. 73: 2126-2126. DOI: 10.1158/1538-7445.Am2013-2126  0.448
2013 Lugo FP, Lin S, Bandyopadhyay A, Yang J, Sun L. Abstract 1392: Role of mutant p53 for anti-TGF-β therapy in isogenic basal-like breast cancer models. Cancer Research. 73: 1392-1392. DOI: 10.1158/1538-7445.Am2013-1392  0.487
2012 Liu Z, Bandyopadhyay A, Nichols RW, Wang L, Hinck AP, Wang S, Sun LZ. Blockade of Autocrine TGF-β Signaling Inhibits Stem Cell Phenotype, Survival, and Metastasis of Murine Breast Cancer Cells. Journal of Stem Cell Research & Therapy. 2: 1-8. PMID 23482850 DOI: 10.4172/2157-7633.1000116  0.515
2012 Kikani CK, Verona EV, Ryu J, Shen Y, Ye Q, Zheng L, Qian Z, Sakaue H, Nakamura K, Du J, Ji Q, Ogawa W, Sun LZ, Dong LQ, Liu F. Proliferative and antiapoptotic signaling stimulated by nuclear-localized PDK1 results in oncogenesis. Science Signaling. 5: ra80. PMID 23131847 DOI: 10.1126/Scisignal.2003065  0.303
2012 Mahlawat P, Ilangovan U, Biswas T, Sun LZ, Hinck AP. Structure of the Alk1 extracellular domain and characterization of its bone morphogenetic protein (BMP) binding properties. Biochemistry. 51: 6328-41. PMID 22799562 DOI: 10.1021/Bi300942X  0.326
2012 Bandyopadhyay A, Dong Q, Sun LZ. Stem/progenitor cells in murine mammary gland: isolation and functional characterization. Methods in Molecular Biology (Clifton, N.J.). 879: 179-93. PMID 22610561 DOI: 10.1007/978-1-61779-815-3_12  0.34
2012 Lin S, Yang J, Elkahloun AG, Bandyopadhyay A, Wang L, Cornell JE, Yeh IT, Agyin J, Tomlinson G, Sun LZ. Attenuation of TGF-β signaling suppresses premature senescence in a p21-dependent manner and promotes oncogenic Ras-mediated metastatic transformation in human mammary epithelial cells. Molecular Biology of the Cell. 23: 1569-81. PMID 22357622 DOI: 10.1091/Mbc.E11-10-0849  0.413
2012 Roy S, Chakravarty D, Cortez V, De Mukhopadhyay K, Bandyopadhyay A, Ahn JM, Raj GV, Tekmal RR, Sun L, Vadlamudi RK. Significance of PELP1 in ER-negative breast cancer metastasis. Molecular Cancer Research : McR. 10: 25-33. PMID 22086908 DOI: 10.1158/1541-7786.Mcr-11-0456  0.455
2012 Mishra S, Sun L. Abstract 5317: Role of TGF-beta superfamily ligand and mechanism of osteoblastic tumorigenesis of prostate cancer cells Cancer Research. 72: 5317-5317. DOI: 10.1158/1538-7445.Am2012-5317  0.508
2012 Mukhopadhyay KD, Elkhaloun AG, Hinck AP, Yoon K, Cornell JE, Yu L, Liu Z, Yang J, Sun L. Abstract 3390: Delineating the molecular signature of the breast cancer-induced brain metastasis and the role of a novel pan-TGF-β inhibitor to block brain metastasis in a mouse xenograft model Cancer Research. 72: 3390-3390. DOI: 10.1158/1538-7445.Am2012-3390  0.404
2012 Mu X, Herzig MC, Washburn WK, Walter CA, Halff GA, Sun L. Abstract 3259: TGFβ signaling is frequently attenuated in hepatocellular carcinomas but is retained for malignant phenotypes in some hepatocellular carcinoma cells Cancer Research. 72: 3259-3259. DOI: 10.1158/1538-7445.Am2012-3259  0.398
2012 Roy SS, Rao M, Sun L, Tekmal RR, Vadlamudi RK. Abstract 2301: Epigenetic regulation of microRNA-200a and 141 by proto-oncogene PELP1: Role in breast cancer progression and metastasis Cancer Research. 72: 2301-2301. DOI: 10.1158/1538-7445.Am2012-2301  0.428
2012 Biswas T, Yang J, Zhao L, Sun L. Abstract 1366: Development of murine models of breast cancer metastasis for the evaluation of the efficacy of TGF-β inhibitors as therapeutic agents Cancer Research. 72: 1366-1366. DOI: 10.1158/1538-7445.Am2012-1366  0.482
2012 Lin S, Yu L, Yang J, Liu Z, Karia B, Bishop AJR, Jackson J, Lozano G, Copland JA, Mu X, Sun B, Sun L. Abstract 1069: Mutant p53 disrupts the role of ShcA in balancing the Smad-dependent and -independent signaling activity of TGF-β Cancer Research. 72: 1069-1069. DOI: 10.1158/1538-7445.Am2012-1069  0.488
2011 Lin S, Yu L, Yang J, Liu Z, Karia B, Bishop AJ, Jackson J, Lozano G, Copland JA, Mu X, Sun B, Sun LZ. Mutant p53 disrupts role of ShcA protein in balancing Smad protein-dependent and -independent signaling activity of transforming growth factor-β (TGF-β). The Journal of Biological Chemistry. 286: 44023-34. PMID 22039050 DOI: 10.1074/Jbc.M111.265397  0.472
2011 Sudarshan S, Shanmugasundaram K, Naylor SL, Lin S, Livi CB, O'Neill CF, Parekh DJ, Yeh IT, Sun LZ, Block K. Reduced expression of fumarate hydratase in clear cell renal cancer mediates HIF-2α accumulation and promotes migration and invasion. Plos One. 6: e21037. PMID 21695080 DOI: 10.1371/Journal.Pone.0021037  0.406
2011 Mukhopadhyay KD, Bandyopadhyay A, Chang TT, Elkahloun AG, Cornell JE, Yang J, Goins BA, Yeh IT, Sun LZ. Isolation and characterization of a metastatic hybrid cell line generated by ER negative and ER positive breast cancer cells in mouse bone marrow. Plos One. 6: e20473. PMID 21673810 DOI: 10.1371/Journal.Pone.0020473  0.44
2011 Huang T, David L, Mendoza V, Yang Y, Villarreal M, De K, Sun L, Fang X, López-Casillas F, Wrana JL, Hinck AP. TGF-β signalling is mediated by two autonomously functioning TβRI:TβRII pairs. The Embo Journal. 30: 1263-76. PMID 21423151 DOI: 10.1038/Emboj.2011.54  0.364
2011 Mishra S, Tang Y, Wang L, deGraffenried L, Yeh IT, Werner S, Troyer D, Copland JA, Sun LZ. Blockade of transforming growth factor-beta (TGFβ) signaling inhibits osteoblastic tumorigenesis by a novel human prostate cancer cell line. The Prostate. 71: 1441-54. PMID 21321980 DOI: 10.1002/Pros.21361  0.428
2011 Mahalingam D, Liang S, Buonamici S, Sun L. Abstract LB-381: Inhibition of the hedgehog signaling pathway has significant preclinical activity and prevents development of androgen-independent prostate cancer Cancer Research. 71. DOI: 10.1158/1538-7445.Am2011-Lb-381  0.37
2011 Biswas T, Sun L. Abstract 542: TGF-β inhibitors enhance chemotherapeutic efficacy via abrogation of autocrine and paracrine signaling in a triple negative breast cancer model Cancer Research. 71: 542-542. DOI: 10.1158/1538-7445.Am2011-542  0.519
2011 Mukhopadhyay KD, Bandyopadhyay A, Elkahloun AG, Cornell JE, Yang J, Sun L. Abstract 5168: Unraveling the molecular signature that drives breast cancer-induced brain metastasis in a mouse xenograft model Cancer Research. 71: 5168-5168. DOI: 10.1158/1538-7445.Am2011-5168  0.369
2011 Liu Z, Mukhopadhyay KD, Yu L, Sun L. Abstract 2430: Aromatase expression inhibits anoikis and promotes bone metastasis of ERα positive breast cancer cells Cancer Research. 71: 2430-2430. DOI: 10.1158/1538-7445.Am2011-2430  0.461
2011 Bandyopadhyay A, Agyin J, Lopez-Casillas F, Wang L, Biswas T, Sun L. Abstract 1753: Comparison between early versus delayed treatment of breast cancer induced osteolytic bone metastasis by TGFβ inhibitors in a murine model Cancer Research. 71: 1753-1753. DOI: 10.1158/1538-7445.Am2011-1753  0.45
2011 Mishra S, Tang Y, Werner SL, Sun L. Abstract 1482: Role of TGF-beta signaling and mechanism of osteoblastic tumorigenesis in prostate cancer Cancer Research. 71: 1482-1482. DOI: 10.1158/1538-7445.Am2011-1482  0.386
2011 Lin S, Yu L, Yang J, Sun L. Abstract 1091: ShcA-mediated ERK signaling contributes to the tumor-promoting activity of TGF-beta in the presence of mutant p53 Cancer Research. 71: 1091-1091. DOI: 10.1158/1538-7445.Am2011-1091  0.476
2011 Mishra S, Sun L. Abstract B106: Role of TGF-beta superfamily ligand and estrogen signaling in mediating osteoblastic tumorigenesis of prostate cancer cells. Molecular Cancer Therapeutics. 10. DOI: 10.1158/1535-7163.Targ-11-B106  0.489
2011 Sudarshan S, Shanmugasundaram K, Naylor S, Lin S, Livi C, Galindo C, Parekh D, Yeh I, Sun L, Block K. 384 REDUCED EXPRESSION OF FUMARATE HYDRATASE IN CLEAR CELL RENAL CANCER PROMOTES HIF-2α ACCUMULATION, MIGRATION AND INVASION The Journal of Urology. 185. DOI: 10.1016/J.Juro.2011.02.472  0.396
2010 Chakravarty D, Nair SS, Santhamma B, Nair BC, Wang L, Bandyopadhyay A, Agyin JK, Brann D, Sun LZ, Yeh IT, Lee FY, Tekmal RR, Kumar R, Vadlamudi RK. Extranuclear functions of ER impact invasive migration and metastasis by breast cancer cells. Cancer Research. 70: 4092-101. PMID 20460518 DOI: 10.1158/0008-5472.Can-09-3834  0.415
2010 Bandyopadhyay A, Wang L, Agyin J, Tang Y, Lin S, Yeh IT, De K, Sun LZ. Doxorubicin in combination with a small TGFbeta inhibitor: a potential novel therapy for metastatic breast cancer in mouse models. Plos One. 5: e10365. PMID 20442777 DOI: 10.1371/Journal.Pone.0010365  0.491
2010 De K, Liu Z, Yu L, Sun L. Abstract LB-203: Aromatase expression promotes breast cancer tumorigenesis and bone metastasis Cancer Research. 70. DOI: 10.1158/1538-7445.Am10-Lb-203  0.483
2010 Lin S, Yang J, Yu L, Sun L. Abstract 3968: Mutation and phosphorylation of p53 may switch TGF-beta from a tumor suppressor to a tumor promoter Cancer Research. 70: 3968-3968. DOI: 10.1158/1538-7445.Am10-3968  0.44
2010 Bandyopadhyay AM, De K, Biswas T, Herzig M, Walter CA, Sun L. Abstract 3469: Effect of age and mutagen on the enriched murine mammary epithelial stem and progenitor cell population Cancer Research. 70: 3469-3469. DOI: 10.1158/1538-7445.Am10-3469  0.306
2009 Lei X, Wang L, Yang J, Sun LZ. TGFbeta signaling supports survival and metastasis of endometrial cancer cells. Cancer Management and Research. 2009: 15-24. PMID 20622970  0.385
2009 Lei X, Wang L, Yang J, Sun L. TGFβ signaling supports survival and metastasis of endometrial cancer cells Cancer Management and Research. 1: 15-24. DOI: 10.2147/Cmar.S4545  0.478
2009 Sun L, Tang Y, Mishra S, Graffenried LD, Werner S, Troyer D, Thompson I. Abstract B108: Inhibition of osteoblastic tumorigenesis of a novel human prostate cancer cell line by the blockade of TGF‐β signaling Molecular Cancer Therapeutics. 8. DOI: 10.1158/1535-7163.Targ-09-B108  0.429
2008 Verona EV, Tang Y, Millstead TK, Hinck AP, Agyin JK, Sun LZ. Expression, purification and characterization of BG(E)RII: a novel pan-TGFbeta inhibitor. Protein Engineering, Design & Selection : Peds. 21: 463-73. PMID 18499679 DOI: 10.1093/Protein/Gzn023  0.345
2008 Le Scolan E, Zhu Q, Wang L, Bandyopadhyay A, Javelaud D, Mauviel A, Sun L, Luo K. Transforming growth factor-beta suppresses the ability of Ski to inhibit tumor metastasis by inducing its degradation. Cancer Research. 68: 3277-85. PMID 18451154 DOI: 10.1158/0008-5472.Can-07-6793  0.444
2008 Yu W, Jia L, Wang P, Lawson KA, Simmons-Menchaca M, Park SK, Sun L, Sanders BG, Kline K. In vitro and in vivo evaluation of anticancer actions of natural and synthetic vitamin E forms. Molecular Nutrition & Food Research. 52: 447-56. PMID 18381678 DOI: 10.1002/Mnfr.200700254  0.325
2007 Gumz ML, Zou H, Kreinest PA, Childs AC, Belmonte LS, LeGrand SN, Wu KJ, Luxon BA, Sinha M, Parker AS, Sun LZ, Ahlquist DA, Wood CG, Copland JA. Secreted frizzled-related protein 1 loss contributes to tumor phenotype of clear cell renal cell carcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 4740-9. PMID 17699851 DOI: 10.1158/1078-0432.Ccr-07-0143  0.354
2007 Verona EV, Elkahloun AG, Yang J, Bandyopadhyay A, Yeh IT, Sun LZ. Transforming growth factor-beta signaling in prostate stromal cells supports prostate carcinoma growth by up-regulating stromal genes related to tissue remodeling. Cancer Research. 67: 5737-46. PMID 17575140 DOI: 10.1158/0008-5472.Can-07-0444  0.477
2007 Lei X, Yang J, Nichols RW, Sun L. Abrogation of TGFβ Signaling Induces Apoptosis Through the Modulation of MAP Kinase Pathways in Breast Cancer Cells Experimental Cell Research. 313: 1687-1695. PMID 17382930 DOI: 10.1016/J.Yexcr.2007.02.016  0.442
2007 Bandyopadhyay A, Wang L, Chin SH, Sun LZ. Inhibition of skeletal metastasis by ectopic ERalpha expression in ERalpha-negative human breast cancer cell lines. Neoplasia (New York, N.Y.). 9: 113-8. PMID 17356707 DOI: 10.1593/Neo.06784  0.449
2007 Zhu Q, Krakowski AR, Dunham EE, Wang L, Bandyopadhyay A, Berdeaux R, Martin GS, Sun L, Luo K. Dual role of SnoN in mammalian tumorigenesis. Molecular and Cellular Biology. 27: 324-39. PMID 17074815 DOI: 10.1128/Mcb.01394-06  0.501
2006 Bandyopadhyay A, Agyin JK, Wang L, Tang Y, Lei X, Story BM, Cornell JE, Pollock BH, Mundy GR, Sun LZ. Inhibition of pulmonary and skeletal metastasis by a transforming growth factor-beta type I receptor kinase inhibitor. Cancer Research. 66: 6714-21. PMID 16818646 DOI: 10.1158/0008-5472.Can-05-3565  0.481
2005 Bandyopadhyay A, Elkahloun A, Baysa SJ, Wang L, Sun LZ. Development and gene expression profiling of a metastatic variant of the human breast cancer MDA-MB-435 cells. Cancer Biology & Therapy. 4: 168-74. PMID 15655343 DOI: 10.4161/Cbt.4.2.1436  0.462
2005 Bandyopadhyay A, Wang L, López-Casillas F, Mendoza V, Yeh IT, Sun L. Systemic administration of a soluble betaglycan suppresses tumor growth, angiogenesis, and matrix metalloproteinase-9 expression in a human xenograft model of prostate cancer. The Prostate. 63: 81-90. PMID 15468171 DOI: 10.1002/Pros.20166  0.419
2004 Anderson K, Lawson KA, Simmons-Menchaca M, Sun L, Sanders BG, Kline K. Alpha-TEA plus cisplatin reduces human cisplatin-resistant ovarian cancer cell tumor burden and metastasis. Experimental Biology and Medicine (Maywood, N.J.). 229: 1169-76. PMID 15564444 DOI: 10.1177/153537020422901112  0.335
2004 Lawson KA, Anderson K, Snyder RM, Simmons-Menchaca M, Atkinson J, Sun LZ, Bandyopadhyay A, Knight V, Gilbert BE, Sanders BG, Kline K. Novel vitamin E analogue and 9-nitro-camptothecin administered as liposome aerosols decrease syngeneic mouse mammary tumor burden and inhibit metastasis. Cancer Chemotherapy and Pharmacology. 54: 421-31. PMID 15197487 DOI: 10.1007/S00280-004-0817-Y  0.345
2004 Sun L. Tumor-suppressive and promoting function of transforming growth factor beta Frontiers in Bioscience. 9: 1925-1935. PMID 14977598 DOI: 10.2741/1382  0.43
2002 Lei X, Bandyopadhyay A, Le T, Sun L. Autocrine TGFbeta supports growth and survival of human breast cancer MDA-MB-231 cells. Oncogene. 21: 7514-23. PMID 12386814 DOI: 10.1038/Sj.Onc.1205966  0.458
2002 Ahmed MM, Alcock RA, Chendil D, Dey S, Das A, Venkatasubbarao K, Mohiuddin M, Sun L, Strodel WE, Freeman JW. Restoration of transforming growth factor-beta signaling enhances radiosensitivity by altering the Bcl-2/Bax ratio in the p53 mutant pancreatic cancer cell line MIA PaCa-2. The Journal of Biological Chemistry. 277: 2234-46. PMID 11694525 DOI: 10.1074/Jbc.M110168200  0.36
1998 Bandyopadhyay A, Cibull ML, Sun L. Isolation and characterization of a spontaneously transformed malignant mouse mammary epithelial cell line in culture. Carcinogenesis. 19: 1907-1911. PMID 9855001 DOI: 10.1093/Carcin/19.11.1907  0.44
1998 Ammanamanchi S, Kim SJ, Sun LZ, Brattain MG. Induction of transforming growth factor-β receptor type II expression in estrogen receptor-positive breast cancer cells through SP1 activation by 5-aza-2'-deoxycytidine Journal of Biological Chemistry. 273: 16527-16534. PMID 9632722 DOI: 10.1074/Jbc.273.26.16527  0.439
1997 Sun L, Chen C. Expression of transforming growth factor beta type III receptor suppresses tumorigenicity of human breast cancer MDA-MB-231 cells. The Journal of Biological Chemistry. 272: 25367-72. PMID 9312157 DOI: 10.1074/jbc.272.40.25367  0.379
1997 Chen C, Wang XF, Sun L. Expression of Transforming Growth Factor β (TGFβ) Type III Receptor Restores Autocrine TGFβ1 Activity in Human Breast Cancer MCF-7 Cells Journal of Biological Chemistry. 272: 12862-12867. PMID 9139748 DOI: 10.1074/Jbc.272.19.12862  0.478
1996 Periyasamy S, Sun L, Gentry LE, Brattain MG. Differential control of expression of type I and type II receptors of transforming growth factor-β in colon carcinoma cells Journal of Cellular Physiology. 168: 711-720. PMID 8816926 DOI: 10.1002/(Sici)1097-4652(199609)168:3<711::Aid-Jcp24>3.0.Co;2-#  0.426
1996 Wang J, Han W, Zborowska E, Liang J, Wang X, Willson JKV, Sun L, Brattain MG. Reduced expression of transforming growth factor β type I receptor contributes to the malignancy of human colon carcinoma cells Journal of Biological Chemistry. 271: 17366-17371. PMID 8663343 DOI: 10.1074/Jbc.271.29.17366  0.349
1995 Wang J, Sun L, Myeroff L, Wang X, Gentry LE, Yang J, Liang J, Zborowska E, Markowitz S, Willson JK. Demonstration that mutation of the type II transforming growth factor beta receptor inactivates its tumor suppressor activity in replication error-positive colon carcinoma cells. The Journal of Biological Chemistry. 270: 22044-9. PMID 7665626 DOI: 10.1074/Jbc.270.37.22044  0.429
1995 Wang D, Birkenmeier TM, Yang J, Venkateswarlu S, Humphrey L, Brattain MG, Sun L. Release from quiescence stimulates the expression of integrin α5β1 which regulates DNA synthesis in human fibrosarcoma HT1080 cells Journal of Cellular Physiology. 164: 499-508. PMID 7650060 DOI: 10.1002/Jcp.1041640308  0.313
1994 Sun L, Shaoping WU, Coleman K, Fields KC, Humphrey LE, Brattain MG. Autocrine transforming growth factor-β1 and β2 expression is increased by cell crowding and quiescence in colon carcinoma cells Experimental Cell Research. 214: 215-224. PMID 8082724 DOI: 10.1006/Excr.1994.1251  0.389
1993 Howell GM, Sun L, Ziober BL, Wu SP, Brattain MG. The role of growth regulatory aberrations in progression of human colon carcinoma Cancer and Metastasis Reviews. 12: 275-286. PMID 8281613 DOI: 10.1007/Bf00665958  0.327
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