| Year |
Citation |
Score |
| 2023 |
Fu J, Wang Z, Martinez M, Obradovic A, Jiao W, Frangaj K, Jones R, Guo XV, Zhang Y, Kuo WI, Ko HM, Iuga A, Bay Muntnich C, Prada Rey A, Rogers K, ... ... Sykes M, et al. Plasticity of intragraft alloreactive T cell clones in human gut correlates with transplant outcomes. The Journal of Experimental Medicine. 221. PMID 38091025 DOI: 10.1084/jem.20230930 |
0.425 |
|
| 2023 |
Fu J, Hsiao T, Waffarn E, Meng W, Long KD, Frangaj K, Jones R, Gorur A, Shtewe A, Li M, Muntnich CB, Rogers K, Jiao W, Velasco M, Matsumoto R, ... ... Sykes M, et al. Dynamic establishment and maintenance of the human intestinal B cell population and repertoire following transplantation. Medrxiv : the Preprint Server For Health Sciences. PMID 38014202 DOI: 10.1101/2023.11.15.23298517 |
0.373 |
|
| 2023 |
Tran LM, Macedo C, Zahorchak AF, Gu X, Elinoff B, Singhi AD, Isett B, Zeevi A, Sykes M, Breen K, Srivastava A, Ables EM, Landsittel D, Styn MA, Humar A, et al. Donor-derived regulatory dendritic cell infusion modulates effector CD8 T cell and NK cell responses after liver transplantation. Science Translational Medicine. 15: eadf4287. PMID 37820009 DOI: 10.1126/scitranslmed.adf4287 |
0.485 |
|
| 2023 |
Sykes M. Leveraging the lymphohematopoietic graft-versus-host reaction (LGVHR) to achieve allograft tolerance and restore self tolerance with minimal toxicity. Immunotherapy Advances. 3: ltad008. PMID 37426630 DOI: 10.1093/immadv/ltad008 |
0.365 |
|
| 2023 |
Talaie T, Wang H, Kuo WI, Danzl N, Gulsen MR, Wolabaugh AN, Ding X, Sykes M, Li HW. Origin, phenotype and autoimmune potential of T cells in human immune system mice receiving neonatal human thymus tissue. Frontiers in Immunology. 14: 1159341. PMID 37251390 DOI: 10.3389/fimmu.2023.1159341 |
0.353 |
|
| 2022 |
Fu J, Rust D, Fang Z, Jiao W, Lagana S, Batal I, Chen B, Merl S, Jones R, Sykes M, Weiner J. T cell repertoire profiling in allografts and native tissues in recipients with COVID-19 after solid organ transplantation: Insight into T cell-mediated allograft protection from viral infection. Frontiers in Immunology. 13: 1056703. PMID 36591281 DOI: 10.3389/fimmu.2022.1056703 |
0.407 |
|
| 2022 |
Li Y, Wu Y, Federzoni EA, Wang X, Dharmawan A, Hu X, Wang H, Hawley RJ, Stevens S, Sykes M, Yang YG. CD47 cross-dressing by extracellular vesicles expressing CD47 inhibits phagocytosis without transmitting cell death signals. Elife. 11. PMID 36454036 DOI: 10.7554/eLife.73677 |
0.313 |
|
| 2022 |
Sykes M. Developing pig-to-human organ transplants. Science (New York, N.Y.). 378: 135-136. PMID 36227981 DOI: 10.1126/science.abo7935 |
0.311 |
|
| 2022 |
Sykes M, Sachs DH. Progress in xenotransplantation: overcoming immune barriers. Nature Reviews. Nephrology. PMID 36198911 DOI: 10.1038/s41581-022-00624-6 |
0.321 |
|
| 2022 |
Nauman G, Danzl NM, Lee J, Borsotti C, Madley R, Fu J, Hölzl MA, Dahmani A, Dorronsoro Gonzalez A, Chavez É, Campbell SR, Yang S, Satwani P, Liu K, Sykes M. Defects in Long-Term APC Repopulation Ability of Adult Human Bone Marrow Hematopoietic Stem Cells (HSCs) Compared with Fetal Liver HSCs. Journal of Immunology (Baltimore, Md. : 1950). PMID 35315788 DOI: 10.4049/jimmunol.2100966 |
0.39 |
|
| 2022 |
Podestà MA, Sykes M. Chimerism-Based Tolerance to Kidney Allografts in Humans: Novel Insights and Future Perspectives. Frontiers in Immunology. 12: 791725. PMID 35069574 DOI: 10.3389/fimmu.2021.791725 |
0.476 |
|
| 2021 |
Obradovic A, Shen Y, Sykes M, Fu J. Integrated Analysis Toolset for Defining and Tracking Alloreactive T-cell Clones After Human Solid Organ and Hematopoietic Stem Cell Transplantation. Software Impacts. 10. PMID 35291378 DOI: 10.1016/j.simpa.2021.100142 |
0.417 |
|
| 2021 |
Fu J, Sykes M. Emerging Concepts of Tissue-resident Memory T Cells in Transplantation. Transplantation. PMID 34873129 DOI: 10.1097/TP.0000000000004000 |
0.401 |
|
| 2021 |
Fu J, Khosravi-Maharlooei M, Sykes M. High Throughput Human T Cell Receptor Sequencing: A New Window Into Repertoire Establishment and Alloreactivity. Frontiers in Immunology. 12: 777756. PMID 34804070 DOI: 10.3389/fimmu.2021.777756 |
0.342 |
|
| 2021 |
Aschauer C, Jelencsics K, Hu K, Heinzel A, Gregorich MG, Vetter J, Schaller S, Winkler SM, Weinberger J, Pimenov L, Gualdoni GA, Eder M, Kainz A, Troescher AR, Regele H, ... ... Sykes M, et al. Prospective Tracking of Donor-Reactive T-Cell Clones in the Circulation and Rejecting Human Kidney Allografts. Frontiers in Immunology. 12: 750005. PMID 34721420 DOI: 10.3389/fimmu.2021.750005 |
0.441 |
|
| 2021 |
Takeuchi K, Ariyoshi Y, Shimizu A, Okumura Y, Cara-Fuentes G, Garcia GE, Pomposelli T, Watanabe H, Boyd L, Ekanayake-Alper DK, Amarnath D, Sykes M, Sachs DH, Johnson RJ, Yamada K. Expression of human CD47 in pig glomeruli prevents proteinuria and prolongs graft survival following pig-to-baboon xenotransplantation. Xenotransplantation. PMID 34418164 DOI: 10.1111/xen.12708 |
0.373 |
|
| 2021 |
Fu J, Zuber J, Shonts B, Obradovic A, Wang Z, Frangaj K, Meng W, Rosenfeld AM, Waffarn EE, Liou P, Lau SP, Savage TM, Yang S, Rogers K, Danzl NM, ... ... Sykes M, et al. Lymphohematopoietic graft-versus-host responses promote mixed chimerism in patients receiving intestinal transplantation. The Journal of Clinical Investigation. PMID 33630757 DOI: 10.1172/JCI141698 |
0.51 |
|
| 2021 |
Khosravi-Maharlooei M, Li H, Hoelzl M, Zhao G, Ruiz A, Misra A, Li Y, Teteloshvili N, Nauman G, Danzl N, Ding X, Pinker EY, Obradovic A, Yang YG, Iuga A, ... ... Sykes M, et al. Role of the thymus in spontaneous development of a multi-organ autoimmune disease in human immune system mice. Journal of Autoimmunity. 119: 102612. PMID 33611150 DOI: 10.1016/j.jaut.2021.102612 |
0.335 |
|
| 2020 |
Alonso-Guallart P, Llore N, Lopes E, Kofman S, Ho SH, Stern J, Pierre G, Bruestle K, Tang Q, Sykes M, Griesemer A. CD40L-stimulated B cells for ex vivo expansion of polyspecific nonhuman primate regulatory T cells for translational studies. Clinical and Experimental Immunology. PMID 33058141 DOI: 10.1111/cei.13537 |
0.47 |
|
| 2020 |
Habal MV, Miller AMI, Rao S, Lin S, Obradovic A, Khosravi-Maharlooei M, See S, Roy P, Ronzon S, Ho SH, Marboe C, Naka Y, Takeda K, Restaino S, Han A, ... ... Sykes M, et al. T cell repertoire analysis suggest a prominent bystander response in human cardiac allograft vasculopathy. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 33021057 DOI: 10.1111/ajt.16333 |
0.368 |
|
| 2020 |
Chaudhry S, Kato Y, Weiner J, Alonso-Guallart P, Baker S, Woodland DC, Lefkowitch JH, Duran-Struuck R, Sondermeijer HP, Zitsman J, Sears ML, Wu A, Karolewski B, Houck PJ, Martinez M, ... ... Sykes M, et al. Transient-mixed Chimerism With Nonmyeloablative Conditioning Does Not Induce Liver Allograft Tolerance in Nonhuman Primates. Transplantation. 104: 1580-1590. PMID 32732835 DOI: 10.1097/Tp.0000000000003263 |
0.425 |
|
| 2020 |
Issa F, Strober S, Leventhal JR, Kawai T, Kaufmann D, Levitsky J, Sykes M, Mas V, Wood KJ, Bridges N, Welniak LA, Chandran S, Madsen JC, Nickerson P, Demetris AJ, et al. The Fourth International Workshop on Clinical Transplant Tolerance. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 32529725 DOI: 10.1111/Ajt.16139 |
0.473 |
|
| 2020 |
Chaudhry S, Kato Y, Weiner J, Alonso-Guallart P, Baker S, Woodland DC, Lefkowitch JH, Duran-Struuck R, Sondermeijer HP, Zitsman J, Sears ML, Wu A, Karolewski B, Houck PJ, Martinez M, ... ... Sykes M, et al. Transient Mixed Chimerism With Nonmyeloablative Conditioning Does Not Induce Liver Allograft Tolerance in Nonhuman Primates. Transplantation. PMID 32265416 DOI: 10.1097/TP.0000000000003263 |
0.312 |
|
| 2020 |
Okumura Y, Takeuchi K, Ariyoshi Y, Pomposelli T, Boyd L, Alper D, Miyake K, Okubo K, Arn S, Shimizu A, Ayares D, Lober M, Sykes M, Sachs DH, Yamada K. Life-Supporting Pig Vascularized-Thymus Plus Kidney Transplantation Leads To Generation Of New Baboon T-Cells And Swine-Specific Hyporesponsiveness Transplantation. 104. DOI: 10.1097/01.Tp.0000702036.32529.4C |
0.482 |
|
| 2020 |
Bruestle K, Sakai H, Fredriksson F, Piegari B, Ekanayake-Alper D, Weiner J, Iuga A, Coley SM, Sykes M, Griesemer A. Advantages Of Rhesus Macaques In A Tolerance Model For Combined Bone Marrow And Kidney Transplantation Transplantation. 104. DOI: 10.1097/01.Tp.0000699124.40779.D6 |
0.457 |
|
| 2020 |
Sakai H, Berglund E, Chaudhry S, Kato Y, Weiner J, Alonso-Guallart P, Llore N, Bruestle K, Fredriksson F, Stern J, Ekanayake-Alper D, Martinez M, Pierre G, Danton M, Kofman S, ... ... Sykes M, et al. Preclinical Study For Tolerance Induction To Liver Allografts With Rapid Immunosuppression Withdrawal In Cynomolgus Monkeys Transplantation. 104. DOI: 10.1097/01.Tp.0000699096.50072.62 |
0.347 |
|
| 2020 |
Bruestle K, Alonso-Guallart P, Sakai H, Fredriksson F, Piegari B, Lopes E, Pierre G, Shou A, Ekanayake-Alper D, Weiner J, Iuga A, Coley SM, Sykes M, Griesemer A. Primate Tolerance Model Demonstrates Longer Kidney Graft Survival With The Administration Of Polyclonal Ex-Vivo Expanded Tregs Transplantation. 104. DOI: 10.1097/01.Tp.0000699076.61780.02 |
0.419 |
|
| 2020 |
Fu J, Wang Z, Martinez M, Frangaj K, Jones R, Guo XV, Obradovic A, Ma W, Rogers K, Kato T, Shen Y, Sykes M. Single Cell Immune Profiling Of Human Intestinal Allografts Reveals Heterogeneity And Alloreactivity Of Recipient Resident Memory T Cells In Association With Graft Outcomes Transplantation. 104. DOI: 10.1097/01.Tp.0000698616.71945.Ca |
0.451 |
|
| 2019 |
Sykes M, Sachs DH. Transplanting organs from pigs to humans. Science Immunology. 4. PMID 31676497 DOI: 10.1126/Sciimmunol.Aau6298 |
0.442 |
|
| 2019 |
Sellberg F, Berglund D, Binder C, Hope J, Fontenot J, Griesemer A, Sykes M, Sachs DH, Berglund E. Pharmacokinetic and pharmacodynamic study of a clinically effective anti-CD2 monoclonal antibody. Scandinavian Journal of Immunology. e12839. PMID 31630416 DOI: 10.1111/Sji.12839 |
0.443 |
|
| 2019 |
Khosravi-Maharlooei M, Hoelzl M, Li HW, Madley RC, Waffarn EE, Danzl NM, Sykes M. Rapid thymectomy of NSG mice to analyze the role of native and grafted thymi in humanized mice. European Journal of Immunology. PMID 31583677 DOI: 10.1002/Eji.201948205 |
0.362 |
|
| 2019 |
Nauman G, Borsotti C, Danzl N, Khosravi-Maharlooei M, Li HW, Chavez E, Stone S, Sykes M. Reduced positive selection of a human TCR in a swine thymus using a humanized mouse model for xenotolerance induction. Xenotransplantation. e12558. PMID 31565822 DOI: 10.1111/Xen.12558 |
0.487 |
|
| 2019 |
Watanabe H, Ariyoshi Y, Pomposelli T, Takeuchi K, Ekanayake-Alper DK, Boyd LK, Arn SJ, Sahara H, Shimizu A, Ayares D, Lorber MI, Sykes M, Sachs DH, Yamada K. Intra-bone bone marrow transplantation from hCD47 transgenic pigs to baboons prolongs chimerism to >60 days and promotes increased porcine lung transplant survival. Xenotransplantation. e12552. PMID 31544995 DOI: 10.1111/Xen.12552 |
0.455 |
|
| 2019 |
Berglund E, Alonso-Guallart P, Danton M, Sellberg F, Binder C, Fröbom R, Berglund D, Llore N, Sakai H, Iuga A, Ekanayake-Alper D, Reimann KA, Sachs DH, Sykes M, Griesemer A. Safety and pharmacodynamics of anti-CD2 monoclonal antibody treatment in cynomolgus macaques- an experimental study. Transplant International : Official Journal of the European Society For Organ Transplantation. PMID 31523849 DOI: 10.1111/Tri.13524 |
0.429 |
|
| 2019 |
Savage TM, Shonts BA, Lau S, Obradovic A, Robins H, Shaked A, Shen Y, Sykes M. Deletion of donor-reactive T cell clones following human liver transplantation. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 31509321 DOI: 10.1111/Ajt.15592 |
0.505 |
|
| 2019 |
Nomura S, Ariyoshi Y, Watanabe H, Pomposelli T, Takeuchi K, Garcia G, Tasaki M, Ayares D, Sykes M, Sachs D, Johnson R, Yamada K. Transgenic expression of human CD47 reduces phagocytosis of porcine endothelial cells and podocytes by baboon and human macrophages. Xenotransplantation. e12549. PMID 31495971 DOI: 10.1111/Xen.12549 |
0.496 |
|
| 2019 |
Sykes M, Griesemer AD. Transplantation tolerance in nonhuman primates and humans. Bone Marrow Transplantation. 54: 815-821. PMID 31431694 DOI: 10.1038/S41409-019-0620-3 |
0.564 |
|
| 2019 |
Alonso-Guallart P, Duran-Struuck R, Zitsman JS, Sameroff S, Pereira M, Stern J, Berglund E, Llore N, Pierre G, Lopes E, Kofman SB, Danton M, Sondermeijer HP, Woodland D, Kato Y, ... ... Sykes M, et al. Impact of CMV reactivation, treatment approaches and immune reconstitution in a nonmyeloablative tolerance induction protocol in Cynomolgus macaques. Transplantation. PMID 31385931 DOI: 10.1097/Tp.0000000000002893 |
0.475 |
|
| 2019 |
Podestà MA, Binder C, Sellberg F, DeWolf S, Shonts B, Ho SH, Obradovic A, Waffarn E, Danzl N, Berglund D, Sykes M. Siplizumab selectively depletes effector memory T-cells and promotes a relative expansion of alloreactive regulatory T-cells in vitro. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 31319439 DOI: 10.1111/Ajt.15533 |
0.563 |
|
| 2019 |
Sekijima M, Sahara H, Shimizu A, Iwanaga T, Murokawa T, Ariyoshi Y, Pomposelli T, Khosravi Maharlooei M, Sykes M, Yamada K. Preparation of hybrid porcine thymus containing non-human primate thymic epithelial cells in miniature swine. Xenotransplantation. e12543. PMID 31293016 DOI: 10.1111/Xen.12543 |
0.478 |
|
| 2019 |
Khosravi-Maharlooei M, Obradovic A, Misra A, Motwani K, Holzl M, Seay HR, DeWolf S, Nauman G, Danzl N, Li H, Ho SH, Winchester R, Shen Y, Brusko TM, Sykes M. Crossreactive public TCR sequences undergo positive selection in the human thymic repertoire. The Journal of Clinical Investigation. 130. PMID 30920391 DOI: 10.1172/Jci124358 |
0.325 |
|
| 2019 |
Snyder ME, Finlayson MO, Connors TJ, Dogra P, Senda T, Bush E, Carpenter D, Marboe C, Benvenuto L, Shah L, Robbins H, Hook JL, Sykes M, D'Ovidio F, Bacchetta M, et al. Generation and persistence of human tissue-resident memory T cells in lung transplantation. Science Immunology. 4. PMID 30850393 DOI: 10.1126/Sciimmunol.Aav5581 |
0.5 |
|
| 2019 |
Yoshihara S, Li Y, Xia J, Danzl N, Sykes M, Yang YG. Posttransplant Hemophagocytic Lymphohistiocytosis Driven by Myeloid Cytokines and Vicious Cycles of T-Cell and Macrophage Activation in Humanized Mice. Frontiers in Immunology. 10: 186. PMID 30814997 DOI: 10.3389/Fimmu.2019.00186 |
0.474 |
|
| 2019 |
Spitzer TR, Tolkoff-Rubin N, Cosimi B, McAfee S, Dey BR, Chen YB, Delmonico F, Sykes M, Sachs DH, Kawai T. Twenty Year Follow Up of Histocompatibility Leukocyte Antigen-Matched Kidney and Bone Marrow Co-Transplantation for Multiple Myeloma with End Stage Renal Disease: Lessons Learned. Transplantation. PMID 30801529 DOI: 10.1097/Tp.0000000000002669 |
0.507 |
|
| 2019 |
Alonso-Guallart P, Zitsman JS, Stern J, Kofman SB, Woodland D, Ho SH, Sondermeijer HP, Bühler L, Griesemer A, Sykes M, Duran-Struuck R. Characterization, biology, and expansion of regulatory T cells in the Cynomolgus macaque for pre-clinical studies. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 30768842 DOI: 10.1111/Ajt.15313 |
0.477 |
|
| 2019 |
Martinez M, Fu J, Liou P, Lobritto S, Goldner D, Vittorio J, Zuber J, Shonts B, Griesemer A, Sykes M, Kato T. 320.6: Potential biomarkers to guide immunosuppression management in intestinal transplant recipients Transplantation. 103. DOI: 10.1097/01.Tp.0000575508.50186.Cd |
0.414 |
|
| 2019 |
Khosravi‐Maharlooei M, Hoelzl M, Li H, Madley R, Waffarn E, Danzl N, Sykes M. Author response for "Rapid thymectomy of NSG mice to analyze the role of native and grafted thymi in humanized mice" European Journal of Immunology. DOI: 10.1002/Eji.201948205/V2/Response1 |
0.321 |
|
| 2018 |
Fu J, Zuber J, Martinez M, Shonts B, Obradovic A, Wang H, Lau SP, Xia A, Waffarn EE, Frangaj K, Savage TM, Simpson MT, Yang S, Guo XV, Miron M, ... ... Sykes M, et al. Human Intestinal Allografts Contain Functional Hematopoietic Stem and Progenitor Cells that Are Maintained by a Circulating Pool. Cell Stem Cell. PMID 30503142 DOI: 10.1016/J.Stem.2018.11.007 |
0.527 |
|
| 2018 |
Savage TM, Shonts BA, Obradovic A, Dewolf S, Lau S, Zuber J, Simpson MT, Berglund E, Fu J, Yang S, Ho SH, Tang Q, Turka LA, Shen Y, Sykes M. Early expansion of donor-specific Tregs in tolerant kidney transplant recipients. Jci Insight. 3. PMID 30429370 DOI: 10.1172/Jci.Insight.124086 |
0.559 |
|
| 2018 |
DeWolf S, Grinshpun B, Savage T, Lau SP, Obradovic A, Shonts B, Yang S, Morris H, Zuber J, Winchester R, Sykes M, Shen Y. Quantifying size and diversity of the human T cell alloresponse. Jci Insight. 3. PMID 30089728 DOI: 10.1172/Jci.Insight.121256 |
0.494 |
|
| 2018 |
Sykes M. IXA Honorary Member Lecture, 2017: The long and winding road to tolerance. Xenotransplantation. 25: e12419. PMID 29913040 DOI: 10.1111/Xen.12419 |
0.399 |
|
| 2018 |
Proto JD, Doran AC, Subramanian M, Wang H, Zhang M, Sozen E, Rymond CC, Kuriakose G, D'Agati V, Winchester R, Sykes M, Yang YG, Tabas I. Hypercholesterolemia induces T cell expansion in humanized immune mice. The Journal of Clinical Investigation. PMID 29708512 DOI: 10.1172/Jci97785 |
0.408 |
|
| 2018 |
Watanabe H, Sahara H, Nomura S, Tanabe T, Ekanayake-Alper DK, Boyd LK, Louras NJ, Asfour A, Danton MA, Ho SH, Arn SJ, Hawley RJ, Shimizu A, Nagayasu T, Ayares D, ... ... Sykes M, et al. GalT-KO pig lungs are highly susceptible to acute vascular rejection in baboons, which may be mitigated by transgenic expression of hCD47 on porcine blood vessels. Xenotransplantation. PMID 29527745 DOI: 10.1111/Xen.12391 |
0.352 |
|
| 2018 |
Llore N, Stern J, Alonso-Guallart P, Berglund KE, Luga A, Weiner J, Pierre G, Lopes E, Gokova S, Ayares D, Lorber M, Hawley R, Yamada K, Sachs D, Sykes M, et al. Recipient T Regulatory Cells Enhance Chimerism and Prolong Galt-KO pig Skin Graft Survival in Baboons Transplantation. 102: S422. DOI: 10.1097/01.Tp.0000543200.79339.Fa |
0.467 |
|
| 2018 |
Fu J, Zuber J, Shonts B, Bi K, Yates K, Ma W, Obradovic A, Yang S, Ho S, Turka L, Farber D, Haining N, Shen Y, Satwani P, Martinez M, ... ... Sykes M, et al. Clonal and Functional Analysis Reveals the Capacity of Allograft T cells to Join the Circulating Pool after Human Intestinal Transplantation Transplantation. 102: S420-S421. DOI: 10.1097/01.Tp.0000543198.71716.C3 |
0.505 |
|
| 2018 |
Fu J, Zuber J, Shonts B, Obradovic A, Lau S, Waffarn E, Savage T, Yang S, Rogers K, Ho S, Shen Y, Satwani P, Martinez M, Kato T, Sykes M. Role of Graft-derived Graft-versus-Host T cells in Facilitating Multilineage Blood Chimerism after Human Intestinal Transplantation Transplantation. 102: S419-S420. DOI: 10.1097/01.Tp.0000543197.33598.E5 |
0.512 |
|
| 2018 |
Kawai T, Spitzer T, Tolkoff-Rubin N, Sykes M, Colvin RB, Sachs DH, Benedict Cosimi A. Non-Myeloablative Conditioning with Low-Dose Total Body Irradiation in Place of Cyclophosphamide Induces Mixed Chimerism and Long-Term Immunosuppression Free Allograft Survival without Acute Kidney Injury in HLA Mismatched Kidney Transplantation Transplantation. 102: S395. DOI: 10.1097/01.Tp.0000543165.32705.F2 |
0.414 |
|
| 2018 |
Watanabe H, Nomura S, Ariyoshi Y, Pomposelli T, Boyd LK, Tasaki M, Ekanayake-Alper DK, Glor HC, Arn S, Hawley RJ, Sykes M, Sachs DH, Yamada K. Durable Macrochimerism (>8 weeks) and Pig-Specific T and B Cell Unresponsiveness Following hCD47+ Transgenic GalTKO Pig Intra-Bone Bone Marrow Transplantation in Baboons Transplantation. 102: S391. DOI: 10.1097/01.Tp.0000543158.20137.B0 |
0.462 |
|
| 2018 |
Nomura S, Watanabe H, Ariyoshi Y, Pomposelli T, Garcia G, Sekijima M, Boyd LK, Ekanayake-Alper DK, Glor HC, Tanabe T, Arn SJSJ, Hawley RJ, Sykes M, Sachs DH, Richard JJ, et al. Transgenic Expression of hCD47 Minimizes the Development of Proteinuria Following Pig-to-Baboon Kidney Transplantation and Reduces Phagocytosis of Porcine Endothelial Cells and Podocytes Transplantation. 102. DOI: 10.1097/01.Tp.0000543036.39314.A6 |
0.455 |
|
| 2018 |
Watanabe H, Nomura S, Sahara H, Pomposelli T, Ariyoshi Y, Boyd LK, Ekanayake-Alper DK, Tanabe T, Glor HC, Arn S, Hawley RJ, Shimizu A, Ayares D, Lorber MI, Sykes M, et al. Transgenic Expression of hCD47 on Vessels in Porcine GalTKO Lung Grafts in Baboons may Mitigate Acute Vascular Rejection in Baboons Transplantation. 102: S313. DOI: 10.1097/01.Tp.0000543035.62185.Da |
0.326 |
|
| 2018 |
Alonso-Guallart P, Duran-Struuck R, Stern J, Berglund E, Llore N, Zitsman J, Pierre G, Kofman S, Danton M, Gokova S, Lopes E, McMurchy A, Tang Q, Levings M, Sykes M, et al. Megadose Bone Marrow and Regulatory T cells for the Induction of Immune Tolerance in Non-Human Primates Through Durable Mixed Hematopoietic Chimerism Across MHC-barriers Transplantation. 102: S263-S264. DOI: 10.1097/01.Tp.0000542954.80179.6B |
0.458 |
|
| 2018 |
Berglund E, Chaudhry S, Kato Y, Weiner J, Alonso-Guallart P, Llore N, Stern J, Ekanayake-Alper D, Martinez M, Pierre G, Danton M, Kofman S, Ordanes D, Lefkowitch JH, Iuga A, ... ... Sykes M, et al. Induction of Tolerance for Long-Term Liver Allograft Survival Without Immunosuppression in Cynomolgus Monkeys Transplantation. 102: S261. DOI: 10.1097/01.Tp.0000542951.95427.3B |
0.324 |
|
| 2018 |
Fu J, Waffarn E, Shonts B, Meng W, Chen D, Yang S, Ho S, Zuber J, Weisel N, Shlomchik M, Hershberg U, Prak EL, Martinez M, Kato T, Sykes M. Phenotypic and Clonal Analysis of Recipient B cells and Plasma Cells Entering Graft Mucosa Reveals an Association with Rejection and Evolution towards a Resident Memory Phenotype after Human Intestinal Transplantation Transplantation. 102: S15-S16. DOI: 10.1097/01.Tp.0000542556.57100.49 |
0.465 |
|
| 2017 |
Fuchs A, Gliwiński M, Grageda N, Spiering R, Abbas AK, Appel S, Bacchetta R, Battaglia M, Berglund D, Blazar B, Bluestone JA, Bornhäuser M, Ten Brinke A, Brusko TM, Cools N, ... ... Sykes M, et al. Minimum Information about T Regulatory Cells: A Step toward Reproducibility and Standardization. Frontiers in Immunology. 8: 1844. PMID 29379498 DOI: 10.3389/Fimmu.2017.01844 |
0.409 |
|
| 2017 |
Borsotti C, Danzl NM, Nauman G, Hölzl MA, French C, Chavez E, Khosravi-Maharlooei M, Glauzy S, Delmotte FR, Meffre E, Savage DG, Campbell SR, Goland R, Greenberg E, Bi J, ... ... Sykes M, et al. HSC extrinsic sex-related and intrinsic autoimmune disease-related human B-cell variation is recapitulated in humanized mice. Blood Advances. 1: 2007-2018. PMID 29296847 DOI: 10.1182/Bloodadvances.2017006932 |
0.401 |
|
| 2017 |
Sykes M. Immune monitoring of transplant patients in transient mixed chimerism tolerance trials. Human Immunology. PMID 29289741 DOI: 10.1016/J.Humimm.2017.12.011 |
0.532 |
|
| 2017 |
Yamada K, Sykes M, Sachs DH. Tolerance in xenotransplantation. Current Opinion in Organ Transplantation. PMID 28937406 DOI: 10.1097/Mot.0000000000000466 |
0.322 |
|
| 2017 |
Kato Y, Griesemer AD, Wu A, Sondermeijer HP, Weiner JI, Duran-Struuck R, Martinez M, Slate AR, Romanov A, Lefkowitch JH, Sykes M, Kato T. Novel H-shunt Venovenous Bypass for Liver Transplantation in Cynomolgus Macaques. Comparative Medicine. 67: 436-441. PMID 28935006 |
0.304 |
|
| 2017 |
Sui L, Danzl N, Campbell SR, Viola R, Williams D, Xing Y, Wang Y, Phillips N, Poffenberger G, Johannesson B, Oberholzer J, Powers AC, Leibel RL, Chen X, Sykes M, et al. Beta Cell Replacement in Mice Using Human Type 1 Diabetes Nuclear Transfer Embryonic Stem Cells. Diabetes. PMID 28931519 DOI: 10.2337/Db17-0120 |
0.358 |
|
| 2017 |
Tan S, Li Y, Xia J, Jin CH, Hu Z, Duinkerken G, Li Y, Khosravi Maharlooei M, Chavez E, Nauman G, Danzl N, Nakayama M, Roep BO, Sykes M, Yang YG. Type 1 diabetes induction in humanized mice. Proceedings of the National Academy of Sciences of the United States of America. PMID 28874533 DOI: 10.1073/Pnas.1710415114 |
0.482 |
|
| 2017 |
Zuber J, Sykes M. Mechanisms of Mixed Chimerism-Based Transplant Tolerance. Trends in Immunology. PMID 28826941 DOI: 10.1016/J.It.2017.07.008 |
0.553 |
|
| 2017 |
DeWolf S, Sykes M. Alloimmune T cells in transplantation. The Journal of Clinical Investigation. PMID 28628037 DOI: 10.1172/Jci90595 |
0.543 |
|
| 2017 |
Gao B, Gu Y, Rong C, Moore C, Porcheray F, Wong W, Preffer F, Saidman SL, Fu Y, Cosimi B, Sachs DH, Kawai T, Sykes M, Zorn E. Dynamics of B cell recovery following kidney/bone marrow transplant recipients. Transplantation. PMID 28422925 DOI: 10.1097/Tp.0000000000001789 |
0.492 |
|
| 2017 |
Sprangers B, DeWolf S, Savage TM, Morokata T, Obradovic A, LoCascio SA, Shonts B, Zuber J, Lau SP, Shah R, Morris H, Steshenko V, Zorn E, Preffer FI, Olek S, ... ... Sykes M, et al. Origin of enriched regulatory t cells in patients receiving combined kidney/bone marrow transplantation to induce transplantation tolerance. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 28251801 DOI: 10.1111/Ajt.14251 |
0.6 |
|
| 2017 |
Fu J, Zuber J, Shonts B, Obradovic A, Lau S, Savage T, Xia A, Simpson M, Yang S, Miron M, Shen Y, Farber D, Martinez M, Griesemer A, Kato T, ... Sykes M, et al. Mixed Chimerism in Peripheral Blood and Allograft after Human Intestinal Transplantation and its Relationship with Clinical Outcomes Transplantation. 101: S92. DOI: 10.1097/01.Tp.0000521419.83368.43 |
0.405 |
|
| 2017 |
Fu J, Zuber J, Shonts B, Wang H, Lau S, Savage T, Xia A, Yang S, Miron M, Farber D, Martinez M, Kato T, Sykes M. Phenotype and Function of Human Gut Hematopoietic Stem Cells and Progenitors Transplantation. 101: S5-S6. DOI: 10.1097/01.Tp.0000521280.76363.Dd |
0.324 |
|
| 2017 |
Fu J, Zuber J, Shonts B, Obradovic A, Lau S, Savage T, Xia A, Simpson M, Yang S, Miron M, Shen Y, Farber D, Martinez M, Griesemer A, Kato T, ... Sykes M, et al. Differing Mechanisms for Early Versus Persistent Donor T cell Chimerism in Peripheral Blood of Human Intestinal Transplant Recipients Transplantation. 101: S63-S64. DOI: 10.1097/01.Tp.0000520398.69592.90 |
0.525 |
|
| 2016 |
Zuber J, Shonts B, Lau SP, Obradovic A, Fu J, Yang S, Lambert M, Coley S, Weiner J, Thome J, DeWolf S, Farber DL, Shen Y, Caillat-Zucman S, Bhagat G, ... ... Sykes M, et al. Bidirectional intragraft alloreactivity drives the repopulation of human intestinal allografts and correlates with clinical outcome. Science Immunology. 1. PMID 28239678 DOI: 10.1126/Sciimmunol.Aah3732 |
0.574 |
|
| 2016 |
Weiner J, Zuber J, Shonts B, Yang S, Fu J, Martinez M, Farber D, Kato T, Sykes M. Long-Term Persistence of Innate Lymphoid Cells in the Gut After Intestinal Transplantation. Transplantation. PMID 27941430 DOI: 10.1097/Tp.0000000000001593 |
0.488 |
|
| 2016 |
Duran-Struuck R, Sondermeijer HP, Bühler L, Alonso-Guallart P, Zitsman J, Kato Y, Wu A, McMurchy AN, Woodland D, Griesemer A, Martinez M, Boskovic S, Kawai T, Cosimi AB, Wuu CS, ... ... Sykes M, et al. Effect of ex vivo Expanded Recipient Regulatory T Cells on Hematopoietic Chimerism and Kidney Allograft Tolerance Across MHC Barriers in Cynomolgus Macaques. Transplantation. PMID 27846155 DOI: 10.1097/Tp.0000000000001559 |
0.559 |
|
| 2016 |
Li HW, Vishwasrao P, HÖlzl MA, Chen S, Choi G, Zhao G, Sykes M. Impact of mixed xenogeneic porcine hematopoietic chimerism on human NK cell recognition in a humanized mouse model. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 27401926 DOI: 10.1111/Ajt.13957 |
0.413 |
|
| 2016 |
Xia J, Hu Z, Yoshihara S, Li Y, Jin CH, Tan S, Li W, Chen Q, Sykes M, Yang YG. Modeling Human Leukemia Immunotherapy in Humanized Mice. Ebiomedicine. PMID 27394641 DOI: 10.1016/J.Ebiom.2016.06.028 |
0.446 |
|
| 2016 |
Markmann JF, Bartlett ST, Johnson P, Korsgren O, Hering BJ, Scharp D, Kay TW, Bromberg J, Odorico JS, Weir GC, Bridges N, Kandaswamy R, Stock P, Friend P, Gotoh M, ... ... Sykes M, et al. Executive Summary of IPITA-TTS Opinion Leaders Report on the Future of β-Cell Replacement. Transplantation. PMID 27082827 DOI: 10.1097/Tp.0000000000001054 |
0.467 |
|
| 2016 |
Bartlett ST, Markmann JF, Johnson P, Korsgren O, Hering BJ, Scharp D, Kay TW, Bromberg J, Odorico JS, Weir GC, Bridges N, Kandaswamy R, Stock P, Friend P, Gotoh M, ... ... Sykes M, et al. Report from IPITA-TTS Opinion Leaders Meeting on the Future of β-Cell Replacement. Transplantation. 100: S1-S44. PMID 26840096 DOI: 10.1097/Tp.0000000000001055 |
0.353 |
|
| 2016 |
DeWolf S, Shen Y, Sykes M. A New Window into the Human Alloresponse. Transplantation. PMID 26760572 DOI: 10.1097/Tp.0000000000001064 |
0.517 |
|
| 2016 |
Sykes M. Immune tolerance in recipients of combined haploidentical bone marrow and kidney transplantation. Bone Marrow Transplantation. S82-6. PMID 26039215 DOI: 10.1038/Bmt.2015.102 |
0.523 |
|
| 2015 |
Weiner J, Duran-Struuck R, Zitsman J, Buhler L, Sondermeijer H, McMurchy AN, Levings MK, Sykes M, Griesemer A. Restimulation After Cryopreservation and Thawing Preserves the Phenotype and Function of Expanded Baboon Regulatory T Cells. Transplantation Direct. 1: 1-7. PMID 27019869 DOI: 10.1097/Txd.0000000000000511 |
0.403 |
|
| 2015 |
Hirata Y, Li HW, Takahashi K, Ishii H, Sykes M, Fujisaki J. MHC Class I Expression by Donor Hematopoietic Stem Cells Is Required to Prevent NK Cell Attack in Allogeneic, but Not Syngeneic Recipient Mice. Plos One. 10: e0141785. PMID 26544200 DOI: 10.1371/Journal.Pone.0141785 |
0.46 |
|
| 2015 |
Newell KA, Asare A, Sanz I, Wei C, Rosenberg A, Gao Z, Kanaparthi S, Asare S, Lim N, Stahly M, Howell M, Knechtle S, Kirk A, Marks WH, Kawai T, ... ... Sykes M, et al. Longitudinal Studies of a B Cell-Derived Signature of Tolerance in Renal Transplant Recipients. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 26461968 DOI: 10.1111/Ajt.13480 |
0.451 |
|
| 2015 |
DeWolf S, Morris H, Shen Y, Sykes M. Author response to comment on "Tracking donor-reactive T cells: Evidence for clonal deletion in tolerant kidney transplant patients". Science Translational Medicine. 7: 297lr1. PMID 26203080 DOI: 10.1126/Scitranslmed.Aac9461 |
0.484 |
|
| 2015 |
Li HW, Andreola G, Carlson AL, Shao S, Lin CP, Zhao G, Sykes M. Rapid Functional Decline of Activated and Memory Graft-versus-Host-Reactive T Cells Encountering Host Antigens in the Absence of Inflammation. Journal of Immunology (Baltimore, Md. : 1950). 195: 1282-92. PMID 26085679 DOI: 10.4049/Jimmunol.1401511 |
0.514 |
|
| 2015 |
Zuber J, Rosen S, Shonts B, Sprangers B, Savage TM, Richman S, Yang S, Lau SP, DeWolf S, Farber D, Vlad G, Zorn E, Wong W, Emond J, Levin B, ... ... Sykes M, et al. Macrochimerism in Intestinal Transplantation: Association With Lower Rejection Rates and Multivisceral Transplants, Without GVHD. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 25988811 DOI: 10.1111/Ajt.13325 |
0.545 |
|
| 2015 |
Morris H, DeWolf S, Robins H, Sprangers B, LoCascio SA, Shonts BA, Kawai T, Wong W, Yang S, Zuber J, Shen Y, Sykes M. Tracking donor-reactive T cells: Evidence for clonal deletion in tolerant kidney transplant patients. Science Translational Medicine. 7: 272ra10. PMID 25632034 DOI: 10.1126/Scitranslmed.3010760 |
0.574 |
|
| 2015 |
Buchan SL, Manzo T, Flutter B, Rogel A, Edwards N, Zhang L, Sivakumaran S, Ghorashian S, Carpenter B, Bennett CL, Freeman GJ, Sykes M, Croft M, Al-Shamkhani A, Chakraverty R. OX40- and CD27-mediated costimulation synergizes with anti-PD-L1 blockade by forcing exhausted CD8+ T cells to exit quiescence. Journal of Immunology (Baltimore, Md. : 1950). 194: 125-33. PMID 25404365 DOI: 10.4049/Jimmunol.1401644 |
0.494 |
|
| 2015 |
Guallart PA, Zitsman J, Sondermeijer H, Bühler L, Ovanez C, McMurchy A, Levings M, Sykes M, Duran-Struuck R. Phenotype, Function and Expansion of Regulatory T Cells in the Cynomolgus Macaque (Macaca fascicularis) Biology of Blood and Marrow Transplantation. 21: S280-S281. DOI: 10.1016/J.Bbmt.2014.11.445 |
0.376 |
|
| 2015 |
Guallart PA, Zitsman J, Sondermeijer H, Woodland D, Kato Y, Weiner J, Griesemer A, Bühler L, McMurchy A, Levings M, Sykes M, Duran-Struuck R. Induction of Durable Mixed Hematopoietic Chimerism and Immune Tolerance in Monkeys Biology of Blood and Marrow Transplantation. 21: S46-S47. DOI: 10.1016/J.Bbmt.2014.11.040 |
0.336 |
|
| 2014 |
Kawai T, Sachs DH, Sprangers B, Spitzer TR, Saidman SL, Zorn E, Tolkoff-Rubin N, Preffer F, Crisalli K, Gao B, Wong W, Morris H, LoCascio SA, Sayre P, Shonts B, ... ... Sykes M, et al. Long-term results in recipients of combined HLA-mismatched kidney and bone marrow transplantation without maintenance immunosuppression. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 14: 1599-611. PMID 24903438 DOI: 10.1111/Ajt.12731 |
0.468 |
|
| 2014 |
Kalscheuer H, Onoe T, Dahmani A, Li HW, Hölzl M, Yamada K, Sykes M. Xenograft tolerance and immune function of human T cells developing in pig thymus xenografts. Journal of Immunology (Baltimore, Md. : 1950). 192: 3442-50. PMID 24591363 DOI: 10.4049/Jimmunol.1302886 |
0.54 |
|
| 2014 |
Griesemer A, Yamada K, Sykes M. Xenotransplantation: immunological hurdles and progress toward tolerance. Immunological Reviews. 258: 241-58. PMID 24517437 DOI: 10.1111/Imr.12152 |
0.458 |
|
| 2014 |
Sykes M. Transplantation: moving to the next level. Immunological Reviews. 258: 5-11. PMID 24517422 DOI: 10.1111/Imr.12161 |
0.512 |
|
| 2014 |
Sachs DH, Kawai T, Sykes M. Induction of tolerance through mixed chimerism. Cold Spring Harbor Perspectives in Medicine. 4: a015529. PMID 24384815 DOI: 10.1101/Cshperspect.A015529 |
0.512 |
|
| 2014 |
Haspot F, Li HW, Lucas CL, Fehr T, Beyaz S, Sykes M. Allospecific rejection of MHC class I-deficient bone marrow by CD8 T cells. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 14: 49-58. PMID 24304495 DOI: 10.1111/Ajt.12525 |
0.806 |
|
| 2014 |
Gao B, Rong C, Moore C, Porcheray F, Wong W, Kawai T, Sykes M, Cosimi B, Sachs D, Zorn E. Dynamics of B Cell Recovery in Tolerant Recipients of Combined Kidney Bone Marrow Transplantation. Transplantation. 98: 896. DOI: 10.1097/00007890-201407151-03062 |
0.39 |
|
| 2014 |
Rosen S, Zuber J, Sprangers B, Richman S, Shonts B, Coley S, Munir S, Yang S, Zorn E, Martinez M, Wong W, Emond J, Kato T, Sykes M. T Cell and Myeloid Chimerism Without GVHD in Human Intestinal and Liver Transplantation: A Prospective Study. Transplantation. 98: 872. DOI: 10.1097/00007890-201407151-02976 |
0.49 |
|
| 2014 |
Weiner J, Duran-Struuck R, Zitsman J, Sykes M, Griesemer A. Resting and Restimulation after Cryopreservation Restores Regulatory T Cell Phenotype and Function. Transplantation. 98: 677-678. DOI: 10.1097/00007890-201407151-02299 |
0.379 |
|
| 2014 |
Kato Y, Griesemer A, Duran-Struuck R, Wu A, Woodland D, Weiner J, Ohmura Y, Martinez M, Alonso P, Baker S, Karolewski B, Lefkowitch J, Kawai T, Kato T, Sykes M. The First Tolerance Induction Model for Combined Liver and Donor Bone Marrow Transplantation in Cynomolgus Monkey. Transplantation. 98: 398. DOI: 10.1097/00007890-201407151-01310 |
0.46 |
|
| 2014 |
Zuber J, Shonts B, Coley S, Sprangers B, Saksa D, Remotti H, DeWolf S, Yang S, Wong W, Zorn E, Lukose T, Gonda T, Martinez M, Kato T, Sykes M. Recipient Cell Turnover of Gut-Resident Lymphocytes in Intestinal Allografts - Association of Delayed Turnover With Non-Rejecting Allografts. Transplantation. 98: 316. DOI: 10.1097/00007890-201407151-01003 |
0.483 |
|
| 2014 |
Zuber J, Shonts B, Savage T, Sprangers B, Coley S, DeWolf S, Wong W, Yang S, Shen Y, Martinez M, Kato T, Sykes M. Thymic Generation of Donor-Derived T Cell From Intestinal Lymphoid Progenitors After Human Small Bowel Transplantation. Transplantation. 98: 311. DOI: 10.1097/00007890-201407151-00984 |
0.511 |
|
| 2014 |
De Wolf S, Morris H, Robins H, Kawai T, Shen Y, Sykes M. Role of Deletion of Donor-Reactive T Cells in Long-Term Human Allograft Tolerance Achieved Via Combined Kidney and Bone Marrow Transplantation (CKBMT). Transplantation. 98: 221-222. DOI: 10.1097/00007890-201407151-00654 |
0.537 |
|
| 2013 |
Cosimi AB, Sachs DH, Sykes M, Kawai T. Clinical strategy for induction of transplantation tolerance through mixed chimerism. Clinical Transplants. 127-34. PMID 25095501 |
0.391 |
|
| 2013 |
Sathaliyawala T, Kubota M, Yudanin N, Turner D, Camp P, Thome JJ, Bickham KL, Lerner H, Goldstein M, Sykes M, Kato T, Farber DL. Distribution and compartmentalization of human circulating and tissue-resident memory T cell subsets. Immunity. 38: 187-97. PMID 23260195 DOI: 10.1016/J.Immuni.2012.09.020 |
0.413 |
|
| 2012 |
Li HW, Sachs J, Pichardo C, Bronson R, Zhao G, Sykes M. Nonalloreactive T cells prevent donor lymphocyte infusion-induced graft-versus-host disease by controlling microbial stimuli. Journal of Immunology (Baltimore, Md. : 1950). 189: 5572-81. PMID 23136200 DOI: 10.4049/Jimmunol.1200045 |
0.514 |
|
| 2012 |
Wang H, Yang Y, Wang G, Wang S, Yeap BY, Sykes M, Yang YG. Donor bone marrow-derived T cells inhibit GVHD induced by donor lymphocyte infusion in established mixed allogeneic hematopoietic chimeras. Plos One. 7: e47120. PMID 23077554 DOI: 10.1371/Journal.Pone.0047120 |
0.575 |
|
| 2012 |
Li HW, Sykes M. Emerging concepts in haematopoietic cell transplantation. Nature Reviews. Immunology. 12: 403-16. PMID 22627859 DOI: 10.1038/Nri3226 |
0.445 |
|
| 2012 |
Kalscheuer H, Danzl N, Onoe T, Faust T, Winchester R, Goland R, Greenberg E, Spitzer TR, Savage DG, Tahara H, Choi G, Yang YG, Sykes M. A model for personalized in vivo analysis of human immune responsiveness. Science Translational Medicine. 4: 125ra30. PMID 22422991 DOI: 10.1126/Scitranslmed.3003481 |
0.468 |
|
| 2011 |
Lucas CL, Sykes M. Layers of regulation in induction of mixed chimerism by anti-CD40L. Chimerism. 2: 111-3. PMID 22509427 DOI: 10.4161/Chim.2.4.19053 |
0.774 |
|
| 2011 |
Sykes M, Levy G. Advances in transplantation. Seminars in Immunology. 23: 222-3. PMID 21943504 DOI: 10.1016/J.Smim.2011.08.013 |
0.462 |
|
| 2011 |
Onoe T, Kalscheuer H, Danzl N, Chittenden M, Zhao G, Yang YG, Sykes M. Human natural regulatory T cell development, suppressive function, and postthymic maturation in a humanized mouse model. Journal of Immunology (Baltimore, Md. : 1950). 187: 3895-903. PMID 21876039 DOI: 10.4049/Jimmunol.1100394 |
0.476 |
|
| 2011 |
Sachs DH, Sykes M, Kawai T, Cosimi AB. Immuno-intervention for the induction of transplantation tolerance through mixed chimerism. Seminars in Immunology. 23: 165-73. PMID 21839648 DOI: 10.1016/J.Smim.2011.07.001 |
0.511 |
|
| 2011 |
Levesque V, Bardwell PD, Shimizu I, Haspot F, Benichou G, Yeap BY, Sykes M. B-cell-dependent memory T cells impede nonmyeloablative mixed chimerism induction in presensitized mice. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 11: 2322-31. PMID 21831158 DOI: 10.1111/J.1600-6143.2011.03683.X |
0.509 |
|
| 2011 |
Strober S, Spitzer TR, Lowsky R, Sykes M. Translational studies in hematopoietic cell transplantation: treatment of hematologic malignancies as a stepping stone to tolerance induction. Seminars in Immunology. 23: 273-81. PMID 21705229 DOI: 10.1016/J.Smim.2011.05.001 |
0.534 |
|
| 2011 |
Farris AB, Taheri D, Kawai T, Fazlollahi L, Wong W, Tolkoff-Rubin N, Spitzer TR, Iafrate AJ, Preffer FI, Locascio SA, Sprangers B, Saidman S, Smith RN, Cosimi AB, Sykes M, et al. Acute renal endothelial injury during marrow recovery in a cohort of combined kidney and bone marrow allografts American Journal of Transplantation. 11: 1464-1477. PMID 21668634 DOI: 10.1111/J.1600-6143.2011.03572.X |
0.521 |
|
| 2011 |
Fujisaki J, Wu J, Carlson AL, Silberstein L, Putheti P, Larocca R, Gao W, Saito TI, Lo Celso C, Tsuyuzaki H, Sato T, Côté D, Sykes M, Strom TB, Scadden DT, et al. In vivo imaging of Treg cells providing immune privilege to the haematopoietic stem-cell niche. Nature. 474: 216-9. PMID 21654805 DOI: 10.1038/Nature10160 |
0.442 |
|
| 2011 |
Andreola G, Chittenden M, Shaffer J, Cosimi AB, Kawai T, Cotter P, Locascio SA, Morokata T, Dey BR, Tolkoff-Rubin NT, Preffer F, Bonnefoix T, Kattleman K, Spitzer TR, Sachs DH, ... Sykes M, et al. Mechanisms of donor-specific tolerance in recipients of haploidentical combined bone marrow/kidney transplantation. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 11: 1236-47. PMID 21645255 DOI: 10.1111/J.1600-6143.2011.03566.X |
0.523 |
|
| 2011 |
Lucas CL, Workman CJ, Beyaz S, LoCascio S, Zhao G, Vignali DA, Sykes M. LAG-3, TGF-β, and cell-intrinsic PD-1 inhibitory pathways contribute to CD8 but not CD4 T-cell tolerance induced by allogeneic BMT with anti-CD40L. Blood. 117: 5532-40. PMID 21422469 DOI: 10.1182/Blood-2010-11-318675 |
0.763 |
|
| 2011 |
Spitzer TR, Sykes M, Tolkoff-Rubin N, Kawai T, McAfee SL, Dey BR, Ballen K, Delmonico F, Saidman S, Sachs DH, Cosimi AB. Long-term follow-up of recipients of combined human leukocyte antigen-matched bone marrow and kidney transplantation for multiple myeloma with end-stage renal disease. Transplantation. 91: 672-6. PMID 21217460 DOI: 10.1097/Tp.0B013E31820A3068 |
0.423 |
|
| 2011 |
Hermanrud CE, Lucas CL, Sykes M, Huang CA, Wang Z. Expression and purification of soluble murine CD40L monomers and polymers in yeast Pichia pastoris. Protein Expression and Purification. 76: 115-20. PMID 21074618 DOI: 10.1016/J.Pep.2010.11.006 |
0.687 |
|
| 2011 |
Flutter B, Edwards N, Zhang L, Sivakumaran S, Croft M, Sykes M, Chakraverty R. Enforced Co-Stimulation and Co-Inhibitory Blockade Synergize to Enhance the Functions of Exhausted CTL Blood. 118: 1911-1911. DOI: 10.1182/Blood.V118.21.1911.1911 |
0.522 |
|
| 2010 |
LoCascio SA, Morokata T, Chittenden M, Preffer FI, Dombkowski DM, Andreola G, Crisalli K, Kawai T, Saidman SL, Spitzer TR, Tolkoff-Rubin N, Cosimi AB, Sachs DH, Sykes M. Mixed chimerism, lymphocyte recovery, and evidence for early donor-specific unresponsiveness in patients receiving combined kidney and bone marrow transplantation to induce tolerance. Transplantation. 90: 1607-15. PMID 21085064 DOI: 10.1097/Tp.0B013E3181Ffbaff |
0.49 |
|
| 2010 |
Flutter B, Edwards N, Fallah-Arani F, Henderson S, Chai JG, Sivakumaran S, Ghorashian S, Bennett CL, Freeman GJ, Sykes M, Chakraverty R. Nonhematopoietic antigen blocks memory programming of alloreactive CD8+ T cells and drives their eventual exhaustion in mouse models of bone marrow transplantation. The Journal of Clinical Investigation. 120: 3855-68. PMID 20978352 DOI: 10.1172/Jci41446 |
0.564 |
|
| 2010 |
Griesemer A, Liang F, Hirakata A, Hirsh E, Lo D, Okumi M, Sykes M, Yamada K, Huang CA, Sachs DH. Occurrence of specific humoral non-responsiveness to swine antigens following administration of GalT-KO bone marrow to baboons. Xenotransplantation. 17: 300-12. PMID 20723202 DOI: 10.1111/J.1399-3089.2010.00600.X |
0.48 |
|
| 2010 |
Sgroi A, Bühler LH, Morel P, Sykes M, Noel L. International human xenotransplantation inventory. Transplantation. 90: 597-603. PMID 20644502 DOI: 10.1097/Tp.0B013E3181Eb2E8C |
0.364 |
|
| 2010 |
Saito TI, Li HW, Sykes M. Invariant NKT cells are required for antitumor responses induced by host-versus-graft responses. Journal of Immunology (Baltimore, Md. : 1950). 185: 2099-105. PMID 20631307 DOI: 10.4049/Jimmunol.0901985 |
0.558 |
|
| 2010 |
Onoe T, Kalscheuer H, Chittenden M, Zhao G, Yang YG, Sykes M. Homeostatic expansion and phenotypic conversion of human T cells depend on peripheral interactions with APCs. Journal of Immunology (Baltimore, Md. : 1950). 184: 6756-65. PMID 20483739 DOI: 10.4049/Jimmunol.0901711 |
0.499 |
|
| 2010 |
Saito TI, Fujisaki J, Carlson AL, Lin CP, Sykes M. Persistence of donor-derived protein in host myeloid cells after induced rejection of engrafted allogeneic bone marrow cells. Experimental Hematology. 38: 333-9. PMID 20167247 DOI: 10.1182/Blood.V114.22.63.63 |
0.567 |
|
| 2010 |
Mollov JL, Lucas CL, Haspot F, Kurtz J, Gaspar C, Guzman A, Sykes M. Recipient dendritic cells, but not B cells, are required antigen-presenting cells for peripheral alloreactive CD8+ T-cell tolerance. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 10: 518-26. PMID 20121730 DOI: 10.1111/J.1600-6143.2009.02967.X |
0.841 |
|
| 2010 |
Sykes M. Immune evasion by chimeric trachea. The New England Journal of Medicine. 362: 172-4. PMID 20071709 DOI: 10.1056/Nejme0908366 |
0.435 |
|
| 2010 |
Nikolic B, Onoe T, Takeuchi Y, Khalpey Z, Primo V, Leykin I, Smith RN, Sykes M. Distinct requirements for achievement of allotolerance versus reversal of autoimmunity via nonmyeloablative mixed chimerism induction in NOD mice. Transplantation. 89: 23-32. PMID 20061915 DOI: 10.1097/Tp.0B013E3181C4692E |
0.359 |
|
| 2010 |
Fehr T, Lucas CL, Kurtz J, Onoe T, Zhao G, Hogan T, Vallot C, Rao A, Sykes M. A CD8 T cell-intrinsic role for the calcineurin-NFAT pathway for tolerance induction in vivo. Blood. 115: 1280-7. PMID 20007805 DOI: 10.1182/Blood-2009-07-230680 |
0.831 |
|
| 2010 |
Yamada K, Nishimura H, Scalea JR, Griesemer A, Moran S, Gillon B, Robson S, Fishman J, Sykes M, Shimizu A, Sachs DH. OPTIMAL T CELL DEPLETION IS ESSENTIAL FOR SUCCESSFUL THYMOKIDNEY TRANSPLANTS IN GALT-KO PIG TO BABOON MODEL Transplantation Journal. 90: 423. DOI: 10.1097/00007890-201007272-00779 |
0.494 |
|
| 2010 |
Morokata T, LoCascio SA, Preffer FI, Dombkowski DM, Andreola G, Crisalli K, Kawai T, Saidman S, Spitzer T, Tolkoff-Rubin N, Cosimi B, Sachs DH, Sykes M. INCREASED FREQUENCY OF REGULATORY T CELLS IN PATIENTS RECEIVING HLA HAPLOIDENTICAL COMBINED KIDNEY AND BONE MARROW TRANSPLANTATION TO INDUCE TOLERANCE Transplantation Journal. 90: 413. DOI: 10.1097/00007890-201007272-00761 |
0.422 |
|
| 2010 |
Nishimura H, Shimizu A, Griesemer A, Scalea JR, Moran S, Weiner J, Gillon B, Fishman J, Robson SC, Sykes M, Sachs DH, Yamada K. HIGH LEVELS OF CYTOTOXIC ANTI-NON GAL PREFORMED NATURAL ANTIBODY DID NOT INDUCE HYPERACUTE REJECTION BUT DID CAUSE EARLY GRAFT LOSS IN A GALT-KO PIG-TO-BABOON THYMOKIDNEY MODEL Transplantation Journal. 90: 311. DOI: 10.1097/00007890-201007272-00586 |
0.364 |
|
| 2010 |
Spinelli J, Sykes M, Kurtz J. Reversal of Autoimmunity by Induction of Mixed Hematopoietic Chimerism: Evidence for Non-deletional Mechanisms Clinical Immunology. 135: S91. DOI: 10.1016/J.Clim.2010.03.272 |
0.661 |
|
| 2010 |
Li H, Saito T, Sykes M. Role of Granzyme B in the Antitumor Effects Induced by Recipient Lymphocyte Infusion in Mixed Bone Marrow Chimeras Clinical Immunology. 135: S12. DOI: 10.1016/J.Clim.2010.03.043 |
0.394 |
|
| 2010 |
Flutter B, Fallah-Arani F, Sivakumaran S, Bennett C, Freeman G, Sykes M, Charaverty R. Non-Hematopoietic Antigen Blocks Early Memory Imprinting Of Graft-Versus-Host Reactive CD8 Cells Biology of Blood and Marrow Transplantation. 16: S307. DOI: 10.1016/J.Bbmt.2009.12.451 |
0.466 |
|
| 2009 |
Griesemer AD, Hirakata A, Shimizu A, Moran S, Tena A, Iwaki H, Ishikawa Y, Schule P, Arn JS, Robson SC, Fishman JA, Sykes M, Sachs DH, Yamada K. Results of gal-knockout porcine thymokidney xenografts. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 9: 2669-78. PMID 19845583 DOI: 10.1111/J.1600-6143.2009.02849.X |
0.533 |
|
| 2009 |
Cozzi E, Tallacchini M, Flanagan EB, Pierson RN, Sykes M, Vanderpool HY. The International Xenotransplantation Association consensus statement on conditions for undertaking clinical trials of porcine islet products in type 1 diabetes--chapter 1: Key ethical requirements and progress toward the definition of an international regulatory framework. Xenotransplantation. 16: 203-14. PMID 19799760 DOI: 10.1111/J.1399-3089.2009.00540.X |
0.33 |
|
| 2009 |
Porcheray F, Wong W, Saidman SL, De Vito J, Girouard TC, Chittenden M, Shaffer J, Tolkoff-Rubin N, Dey BR, Spitzer TR, Colvin RB, Cosimi AB, Kawai T, Sachs DH, Sykes M, et al. B-Cell immunity in the context of t-cell tolerance after combined kidney and bone marrow transplantation in humans American Journal of Transplantation. 9: 2126-2135. PMID 19624570 DOI: 10.1111/J.1600-6143.2009.02738.X |
0.56 |
|
| 2009 |
Habiro K, Sykes M, Yang YG. Induction of human T-cell tolerance to pig xenoantigens via thymus transplantation in mice with an established human immune system. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 9: 1324-9. PMID 19459808 DOI: 10.1111/J.1600-6143.2009.02646.X |
0.52 |
|
| 2009 |
Sykes M. Mechanisms of transplantation tolerance in animals and humans. Transplantation. 87: S67-9. PMID 19424011 DOI: 10.1097/Tp.0B013E3181A2A6B8 |
0.493 |
|
| 2009 |
Brainard DM, Seung E, Frahm N, Cariappa A, Bailey CC, Hart WK, Shin HS, Brooks SF, Knight HL, Eichbaum Q, Yang YG, Sykes M, Walker BD, Freeman GJ, Pillai S, et al. Induction of robust cellular and humoral virus-specific adaptive immune responses in human immunodeficiency virus-infected humanized BLT mice. Journal of Virology. 83: 7305-21. PMID 19420076 DOI: 10.1128/Jvi.02207-08 |
0.392 |
|
| 2009 |
Wang H, Asavaroengchai W, Yeap BY, Wang MG, Wang S, Sykes M, Yang YG. Paradoxical effects of IFN-gamma in graft-versus-host disease reflect promotion of lymphohematopoietic graft-versus-host reactions and inhibition of epithelial tissue injury. Blood. 113: 3612-9. PMID 19211507 DOI: 10.1182/Blood-2008-07-168419 |
0.468 |
|
| 2009 |
Sykes M. Hematopoietic cell transplantation for tolerance induction: animal models to clinical trials. Transplantation. 87: 309-16. PMID 19202432 DOI: 10.1097/Tp.0B013E31819535C2 |
0.447 |
|
| 2009 |
Kurtz J, Raval F, Vallot C, Der J, Sykes M. CTLA-4 on alloreactive CD4 T cells interacts with recipient CD80/86 to promote tolerance. Blood. 113: 3475-84. PMID 19179471 DOI: 10.1182/Blood-2008-01-133736 |
0.763 |
|
| 2009 |
Sachs DH, Sykes M, Yamada K. Achieving tolerance in pig-to-primate xenotransplantation: reality or fantasy. Transplant Immunology. 21: 101-5. PMID 19059481 DOI: 10.1016/J.Trim.2008.11.005 |
0.435 |
|
| 2009 |
Spitzer TR, Sykes M, Tolkoff Rubin N, Kawai T, McAfee SL, Dey B, Ballen K, Delmonico F, Saidman S, Sachs DH, Cosimi B. Long Term Follow-up of Recipients of Combined HLA-Matched Nonmyeloablative Bone Marrow and Kidney Transplantation for Multiple Myeloma with End-Stage Renal Disease. Blood. 114: 3368-3368. DOI: 10.1182/Blood.V114.22.3368.3368 |
0.484 |
|
| 2009 |
Andreola G, Chittenden M, Shaffer J, Cosimi B, Kawai T, Cotter P, Dey B, Tolkoff-Rubin N, Preffer F, Saidman S, Kattleman K, Spitzer T, Sachs D, Sykes M. T.32. Mechanisms of Donor-Specific Unresponsiveness Following Loss of Chimerism in Recipients of Haploidentical Combined Bone Marrow/Kidney Transplantation Clinical Immunology. 131: S60. DOI: 10.1016/J.Clim.2009.03.173 |
0.518 |
|
| 2008 |
Haspot F, Bardwell PD, Zhao G, Sykes M. High antigen levels do not preclude B-cell tolerance induction to alpha1,3-Gal via mixed chimerism. Xenotransplantation. 15: 313-20. PMID 19134161 DOI: 10.1111/J.1399-3089.2008.00487.X |
0.462 |
|
| 2008 |
Fudaba Y, Onoe T, Chittenden M, Shimizu A, Shaffer JM, Bronson R, Sykes M. Abnormal regulatory and effector T cell function predispose to autoimmunity following xenogeneic thymic transplantation. Journal of Immunology (Baltimore, Md. : 1950). 181: 7649-59. PMID 19017953 DOI: 10.4049/Jimmunol.181.11.7649 |
0.573 |
|
| 2008 |
Chakraverty R, Flutter B, Fallah-Arani F, Eom HS, Means T, Andreola G, Schwarte S, Buchli J, Cotter P, Zhao G, Sykes M. The host environment regulates the function of CD8+ graft-versus-host-reactive effector cells. Journal of Immunology (Baltimore, Md. : 1950). 181: 6820-8. PMID 18981100 DOI: 10.4049/Jimmunol.181.10.6820 |
0.565 |
|
| 2008 |
Fehr T, Sykes M. Clinical experience with mixed chimerism to induce transplantation tolerance. Transplant International : Official Journal of the European Society For Organ Transplantation. 21: 1118-35. PMID 18954364 DOI: 10.1111/J.1432-2277.2008.00783.X |
0.495 |
|
| 2008 |
Koporc Z, Pilat N, Nierlich P, Blaha P, Bigenzahn S, Pree I, Selzer E, Sykes M, Muehlbacher F, Wekerle T. Murine Mobilized Peripheral Blood Stem Cells Have a Lower Capacity than Bone Marrow to Induce Mixed Chimerism and Tolerance American Journal of Transplantation. 8: 2025-2036. PMID 18828766 DOI: 10.1111/J.1600-6143.2008.02371.X |
0.585 |
|
| 2008 |
Fehr T, Wang S, Haspot F, Kurtz J, Blaha P, Hogan T, Chittenden M, Wekerle T, Sykes M. Rapid deletional peripheral CD8 T cell tolerance induced by allogeneic bone marrow: role of donor class II MHC and B cells. Journal of Immunology (Baltimore, Md. : 1950). 181: 4371-80. PMID 18768896 DOI: 10.4049/Jimmunol.181.6.4371 |
0.789 |
|
| 2008 |
Shimizu I, Fudaba Y, Shimizu A, Yang YG, Sykes M. Comparison of human T cell repertoire generated in xenogeneic porcine and human thymus grafts. Transplantation. 86: 601-10. PMID 18724231 DOI: 10.1097/Tp.0B013E318182D47A |
0.499 |
|
| 2008 |
Sachs DH, Kawai T, Colvin RB, Fishman JA, Sykes M, Cosimi AB. Response to 'Tolerance versus immunosuppression: A perspective' American Journal of Transplantation. 8: 1573-1574. PMID 18694470 DOI: 10.1111/J.1600-6143.2008.02344.X |
0.316 |
|
| 2008 |
Gibbons C, Sykes M. Manipulating the immune system for anti-tumor responses and transplant tolerance via mixed hematopoietic chimerism. Immunological Reviews. 223: 334-60. PMID 18613846 DOI: 10.1111/J.1600-065X.2008.00636.X |
0.525 |
|
| 2008 |
Ting DT, Spitzer TR, Chaudhary A, Muzikansky A, Colby C, Power K, McAfee S, Ballen K, Attar E, Saidman SL, Preffer F, Sykes M, Dey BR. Clinical outcomes of late rather than early full-donor chimerism in patients with advanced lymphomas receiving nonmyeloablative allogeneic hematopoietic SCT Bone Marrow Transplantation. 42: 329-335. PMID 18587439 DOI: 10.1038/Bmt.2008.167 |
0.404 |
|
| 2008 |
Camirand G, Stéphan L, Rousseau J, Sackett MK, Caron NJ, Mills P, Kurtz J, Sykes M, Rothstein DM, Tremblay JP. Central tolerance to myogenic cell transplants does not include muscle neoantigens. Transplantation. 85: 1791-801. PMID 18580473 DOI: 10.1097/Tp.0B013E31817726Bc |
0.716 |
|
| 2008 |
Haspot F, Fehr T, Gibbons C, Zhao G, Hogan T, Honjo T, Freeman GJ, Sykes M. Peripheral deletional tolerance of alloreactive CD8 but not CD4 T cells is dependent on the PD-1/PD-L1 pathway. Blood. 112: 2149-55. PMID 18577709 DOI: 10.1182/Blood-2007-12-127449 |
0.461 |
|
| 2008 |
Fehr T, Haspot F, Mollov J, Chittenden M, Hogan T, Sykes M. Alloreactive CD8 T cell tolerance requires recipient B cells, dendritic cells, and MHC class II. Journal of Immunology (Baltimore, Md. : 1950). 181: 165-73. PMID 18566381 DOI: 10.4049/Jimmunol.181.1.165 |
0.55 |
|
| 2008 |
Ge X, Brown J, Sykes M, Boussiotis VA. CD134-allodepletion allows selective elimination of alloreactive human T cells without loss of virus-specific and leukemia-specific effectors. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. 14: 518-30. PMID 18410894 DOI: 10.1016/J.Bbmt.2008.02.010 |
0.568 |
|
| 2008 |
Sykes M. 2007 IXA Presidential Address. Progress toward an ideal source animal: opportunities and challenges in a changing world. Xenotransplantation. 15: 7-13. PMID 18333908 DOI: 10.1111/J.1399-3089.2008.00441.X |
0.387 |
|
| 2008 |
Tonomura N, Habiro K, Shimizu A, Sykes M, Yang YG. Antigen-specific human T-cell responses and T cell-dependent production of human antibodies in a humanized mouse model. Blood. 111: 4293-6. PMID 18270327 DOI: 10.1182/Blood-2007-11-121319 |
0.429 |
|
| 2008 |
Kawai T, Cosimi AB, Spitzer TR, Tolkoff-Rubin N, Suthanthiran M, Saidman SL, Shaffer J, Preffer FI, Ding R, Sharma V, Fishman JA, Dey B, Ko DS, Hertl M, Goes NB, ... ... Sykes M, et al. HLA-mismatched renal transplantation without maintenance immunosuppression. The New England Journal of Medicine. 358: 353-61. PMID 18216355 DOI: 10.1056/Nejmoa071074 |
0.486 |
|
| 2008 |
Wang Y, Wang H, Wang S, Sykes M, Yang Y. Characterization of NK1.1+ CD8 T Cells in Allogeneic Hematopoietic Cell Transplantation Recipients Blood. 112: 4616-4616. DOI: 10.1182/Blood.V112.11.4616.4616 |
0.568 |
|
| 2008 |
Andreola G, Chittenden M, Sykes M. Host Environment Determines the Development of Gvhd but Not the Extent of Activation and Expansion of Gvh-Reactive CD4 T Cells Blood. 112: 3508-3508. DOI: 10.1182/Blood.V112.11.3508.3508 |
0.543 |
|
| 2008 |
Andreola G, Chittenden M, Sykes M. Lack of “Bystander” Activation and Evidence for Competition for Resources among Gvh-Reactive CD4 T Cells Blood. 112: 3507-3507. DOI: 10.1182/Blood.V112.11.3507.3507 |
0.529 |
|
| 2008 |
Flutter BR, Fallah-Arani F, Bennett C, Sivakumaran J, Freeman GJ, Sykes M, Chakraverty R. Peripheral Alloantigen Drives Early Dysfunction and Eventual Exhaustion of CTL Following Delayed Donor Leukocyte Infusions. Blood. 112: 2346-2346. DOI: 10.1182/Blood.V112.11.2346.2346 |
0.521 |
|
| 2008 |
Wilson C, Fishman JA, Sykes M. Tribute to Eda T. Bloom, PhD Xenotransplantation. 15: 69-71. DOI: 10.1111/J.1399-3089.2008.00448.X |
0.315 |
|
| 2008 |
Levesque V, Bardwell P, Haspot F, Sykes M. SUCCESSFUL INDUCTION OF MIXED CHIMERISM AND TOLERANCE WITH NON-MYELOABLATIVE CONDITIONING IN MICE PRE-SENSITIZED WITH FULLY MHC MISMATCHED SKIN GRAFTS Transplantation. 86: 46. DOI: 10.1097/01.Tp.0000332675.60725.81 |
0.384 |
|
| 2008 |
Mollov J, Gibbons C, Sykes M. REQUIREMENT FOR MHC CLASS I AND II EXPRESSION ON HOST DENDRITIC CELLS TO TOLERIZE ALLOREACTIVE CD8 CELLS DURING INDUCTION OF MIXED CHIMERISM Transplantation. 86: 229. DOI: 10.1097/01.Tp.0000332178.54814.66 |
0.44 |
|
| 2008 |
Kurtz J, Shubert L, LoCascio S, Sykes M. INDUCTION OF ALLOREACTIVE CD4 TOLERANCE BY CROSS-PRESENTATION OF DONOR MHC MOLECULES BY RECIPIENT APCʼ Transplantation. 86: 228-229. DOI: 10.1097/01.Tp.0000332177.47191.33 |
0.736 |
|
| 2008 |
Kawai T, Sachs D, Spitzer T, Tolkoff-Rubin N, Sykes M, Farrell ML, Colvin R, Cosimi AB. ECONOMIC IMPACT OF TOLERANCE INDUCTION BY COMBINED KIDNEY AND BONE MARROW TRANSPLANTATION Transplantation. 86: 497. DOI: 10.1097/01.tp.0000331305.69987.6e |
0.34 |
|
| 2008 |
Gibbons C, Haspot F, Sykes M. F.94. Overcoming CD8 T Cell-Mediated Resistance to Engraftment of Allogeneic Bone Marrow Cells Clinical Immunology. 127: S74. DOI: 10.1016/J.Clim.2008.03.206 |
0.479 |
|
| 2008 |
Haspot F, Fehr T, Gibbons C, Sykes M. OR.66. Critical Role of Recipient B Cells for CD8 T Cell Tolerance Required to Permit Engraftment of Allogeneic Bone Marrow Cells Clinical Immunology. 127: S27. DOI: 10.1016/J.Clim.2008.03.072 |
0.548 |
|
| 2007 |
Hongo D, Hadidi S, Damrauer S, Garrigue V, Kraft D, Sachs DH, Nikolic B, Sykes M. Porcine thymic grafts protect human thymocytes from HIV-1-induced destruction. The Journal of Infectious Diseases. 196: 900-10. PMID 17703422 DOI: 10.1086/520516 |
0.326 |
|
| 2007 |
Sykes M. Immune tolerance: mechanisms and application in clinical transplantation. Journal of Internal Medicine. 262: 288-310. PMID 17697153 DOI: 10.1111/J.1365-2796.2007.01855.X |
0.448 |
|
| 2007 |
Kawahara T, Rodriguez-Barbosa JI, Zhao Y, Zhao G, Sykes M. Global unresponsiveness as a mechanism of natural killer cell tolerance in mixed xenogeneic chimeras. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 7: 2090-7. PMID 17640313 DOI: 10.1111/J.1600-6143.2007.01905.X |
0.443 |
|
| 2007 |
Shaffer J, Villard J, Means TK, Alexander S, Dombkowski D, Dey BR, McAfee S, Ballen KK, Saidman S, Preffer FI, Sachs DH, Spitzer TR, Sykes M. Regulatory T-cell recovery in recipients of haploidentical nonmyeloablative hematopoietic cell transplantation with a humanized anti-CD2 mAb, MEDI-507, with or without fludarabine Experimental Hematology. 35: 1140-1152. PMID 17588483 DOI: 10.1016/J.Exphem.2007.03.018 |
0.592 |
|
| 2007 |
Yang YG, Sykes M. Xenotransplantation: current status and a perspective on the future. Nature Reviews. Immunology. 7: 519-31. PMID 17571072 DOI: 10.1038/Nri2099 |
0.358 |
|
| 2007 |
Kirk AD, Baldwin WM, Cascalho MI, Chong AS, Sykes M, West LJ. American Society of Transplantation symposium on B cells in transplantation: Harnessing humoral immunity from rodent models to clinical practice American Journal of Transplantation. 7: 1464-1470. PMID 17511676 DOI: 10.1111/J.1600-6143.2007.01815.X |
0.502 |
|
| 2007 |
Sykes M. Mechanisms of tolerance induced via mixed chimerism. Frontiers in Bioscience : a Journal and Virtual Library. 12: 2922-34. PMID 17485269 DOI: 10.2741/2282 |
0.361 |
|
| 2007 |
Dey BR, Shaffer J, Yee AJ, McAfee S, Caron M, Power K, Ting DT, Colby C, Preffer F, Ballen K, Attar E, Saidman S, Tarbell N, Sachs D, Sykes M, et al. Comparison of outcomes after transplantation of peripheral blood stem cells versus bone marrow following an identical nonmyeloablative conditioning regimen. Bone Marrow Transplantation. 40: 19-27. PMID 17468773 DOI: 10.1038/Sj.Bmt.1705688 |
0.554 |
|
| 2007 |
Ide K, Wang H, Tahara H, Liu J, Wang X, Asahara T, Sykes M, Yang YG, Ohdan H. Role for CD47-SIRPalpha signaling in xenograft rejection by macrophages. Proceedings of the National Academy of Sciences of the United States of America. 104: 5062-6. PMID 17360380 DOI: 10.1073/Pnas.0609661104 |
0.425 |
|
| 2007 |
Pree I, Bigenzahn S, Fuchs D, Koporc Z, Nierlich P, Winkler C, Brandacher G, Sykes M, Muehlbacher F, Langer F, Wekerle T. CTLA4Ig promotes the induction of hematopoietic chimerism and tolerance independently of Indoleamine-2,3-dioxygenase. Transplantation. 83: 663-7. PMID 17353791 DOI: 10.1097/01.Tp.0000255594.23445.29 |
0.51 |
|
| 2007 |
Chakraverty R, Sykes M. The role of antigen-presenting cells in triggering graft-versus-host disease and graft-versus-leukemia. Blood. 110: 9-17. PMID 17327406 DOI: 10.1182/Blood-2006-12-022038 |
0.502 |
|
| 2007 |
Koyama I, Nadazdin O, Boskovic S, Ochiai T, Smith RN, Sykes M, Sogawa H, Murakami T, Strom TB, Colvin RB, Sachs DH, Benichou G, Cosimi AB, Kawai T. Depletion of CD8 memory T cells for induction of tolerance of a previously transplanted kidney allograft. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 7: 1055-61. PMID 17286617 DOI: 10.1111/J.1600-6143.2006.01703.X |
0.574 |
|
| 2007 |
Papeta N, Chen T, Vianello F, Gererty L, Malik A, Mok YT, Tharp WG, Bagley J, Zhao G, Stevceva L, Yoon V, Sykes M, Sachs D, Iacomini J, Poznansky MC. Long-term survival of transplanted allogeneic cells engineered to express a T cell chemorepellent. Transplantation. 83: 174-83. PMID 17264814 DOI: 10.1097/01.Tp.0000250658.00925.C8 |
0.49 |
|
| 2007 |
Asavaroengchai W, Wang H, Wang S, Wang L, Bronson R, Sykes M, Yang YG. An essential role for IFN-gamma in regulation of alloreactive CD8 T cells following allogeneic hematopoietic cell transplantation. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. 13: 46-55. PMID 17222752 DOI: 10.1016/J.Bbmt.2006.09.014 |
0.562 |
|
| 2007 |
Shimizu I, Kawahara T, Haspot F, Bardwell PD, Carroll MC, Sykes M. B-cell extrinsic CR1/CR2 promotes natural antibody production and tolerance induction of anti-alphaGAL-producing B-1 cells. Blood. 109: 1773-81. PMID 17023586 DOI: 10.1182/Blood-2006-02-002386 |
0.397 |
|
| 2007 |
Wang H, VerHalen J, Madariaga ML, Xiang S, Wang S, Lan P, Oldenborg PA, Sykes M, Yang YG. Attenuation of phagocytosis of xenogeneic cells by manipulating CD47. Blood. 109: 836-42. PMID 17008545 DOI: 10.1182/Blood-2006-04-019794 |
0.463 |
|
| 2007 |
Dey BR, Yee AJ, McAfee S, Dube C, Ballen K, Attar E, Colby C, Saidman S, Malikowski K, Preffer F, Sykes M, Spitzer TR. Non-Myeloablative T-Cell Depleted (TCD) Haploidentical Hematopoietic Cell Transplantation (HCT) Followed by Donor Leukocyte Infusion(s) for Hematologic Malignancies: The MGH Experience. Blood. 110: 5088-5088. DOI: 10.1182/Blood.V110.11.5088.5088 |
0.51 |
|
| 2007 |
Andreola G, Chittenden M, Shaffer J, Cosimi AB, Kawai T, Cotter P, Dey BR, Tolkoff-Rubin N, Preffer F, Saidman S, Kattleman K, Spitzer TR, Sachs DH, Sykes M. A Role for Regulatory Cells in Tolerance Induction in Recipients of Haploidentical Combined Non-Myeloablative Bone Marrow and Kidney Transplantation?. Blood. 110: 3255-3255. DOI: 10.1182/Blood.V110.11.3255.3255 |
0.584 |
|
| 2007 |
Sachs J, Sykes M. Lymphopenia Promotes the Development of Graft-Versus-Host Disease upon Donor Leukocyte Infusion. Blood. 110: 2185-2185. DOI: 10.1182/Blood.V110.11.2185.2185 |
0.412 |
|
| 2007 |
Ge X, Sykes M, Brown J, Boussiotis VA. Targeting CD134 Results in Selective Depletion of Alloreactive Human T Cells without Loss of Virus-Specific and Leukemia-Specific Effectors. Blood. 110: 2174-2174. DOI: 10.1182/Blood.V110.11.2174.2174 |
0.582 |
|
| 2007 |
Chakraverty R, Flutter B, Eom H, Fallah-Arani F, Zhao G, Sykes M. Clonal Expansion of Graft-Versus-Host Reactive CD8+ T Cells Is Dissociated from Full Effector Differentiation Following Delayed DLI. Blood. 110: 2170-2170. DOI: 10.1182/blood.v110.11.2170.2170 |
0.473 |
|
| 2007 |
Cozzi E, Sykes M. Satellite Symposium held in conjunction with the World Transplant Congress, Boston, 2006 Xenotransplantation. 14: 347-347. DOI: 10.1111/J.1399-3089.2007.00407_1.X |
0.449 |
|
| 2007 |
Haspot F, Fehr T, Hogan T, Honjo T, Sykes M. 24: PD-1 is required to induce peripheral CD8 T cell tolerance in recipients of allogeneic bone marrow transplantation with anti-CD154 Biology of Blood and Marrow Transplantation. 13: 11. DOI: 10.1016/J.Bbmt.2006.12.027 |
0.559 |
|
| 2006 |
Boskovic S, Kawai T, Smith RN, Wee SL, Nadazdin O, Koyama I, Saidman S, Cardarelli F, Elias N, Sykes M, Strom T, Colvin RB, Sachs DH, Cosimi AB. Monitoring antidonor alloantibodies as a predictive assay for renal allograft tolerance/long-term observations in nonhuman primates. Transplantation. 82: 819-25. PMID 17006330 DOI: 10.1097/01.Tp.0000234786.26511.A4 |
0.488 |
|
| 2006 |
Saito TI, Rubio MT, Sykes M. Clinical relevance of recipient leukocyte infusion as antitumor therapy following nonmyeloablative allogeneic hematopoietic cell transplantation. Experimental Hematology. 34: 1271-7. PMID 16939820 DOI: 10.1016/J.Exphem.2006.04.022 |
0.537 |
|
| 2006 |
Chakraverty R, Côté D, Buchli J, Cotter P, Hsu R, Zhao G, Sachs T, Pitsillides CM, Bronson R, Means T, Lin C, Sykes M. An inflammatory checkpoint regulates recruitment of graft-versus-host reactive T cells to peripheral tissues. The Journal of Experimental Medicine. 203: 2021-31. PMID 16880259 DOI: 10.1084/Jem.20060376 |
0.488 |
|
| 2006 |
Murakami M, Ito H, Harada E, Enoki T, Sykes M, Hamano K. Long-term survival of xenogeneic heart grafts achieved by costimulatory blockade and transient mixed chimerism. Transplantation. 82: 275-81. PMID 16858292 DOI: 10.1097/01.Tp.0000226221.53161.10 |
0.473 |
|
| 2006 |
Ito H, Takeuchi Y, Shaffer J, Sykes M. Anti-CD40L monoclonal antibodies can replace anti-CD4 monoclonal antibodies for the nonmyeloablative induction of mixed xenogeneic chimerism. Transplantation. 82: 251-7. PMID 16858289 DOI: 10.1097/01.Tp.0000226147.69877.6F |
0.509 |
|
| 2006 |
Fudaba Y, Spitzer TR, Shaffer J, Kawai T, Fehr T, Delmonico F, Preffer F, Tolkoff-Rubin N, Dey BR, Saidman SL, Kraus A, Bonnefoix T, McAfee S, Power K, Kattleman K, ... ... Sykes M, et al. Myeloma responses and tolerance following combined kidney and nonmyeloablative marrow transplantation: In vivo and in vitro analyses American Journal of Transplantation. 6: 2121-2133. PMID 16796719 DOI: 10.1111/J.1600-6143.2006.01434.X |
0.541 |
|
| 2006 |
Chakraverty R, Eom HS, Sachs J, Buchli J, Cotter P, Hsu R, Zhao G, Sykes M. Host MHC class II+ antigen-presenting cells and CD4 cells are required for CD8-mediated graft-versus-leukemia responses following delayed donor leukocyte infusions. Blood. 108: 2106-13. PMID 16757687 DOI: 10.1182/Blood-2006-03-007427 |
0.57 |
|
| 2006 |
Mapara MY, Leng C, Kim YM, Bronson R, Lokshin A, Luster A, Sykes M. Expression of chemokines in GVHD target organs is influenced by conditioning and genetic factors and amplified by GVHR. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. 12: 623-34. PMID 16737935 DOI: 10.1016/J.Bbmt.2006.02.005 |
0.468 |
|
| 2006 |
Rubio MT, Zhao G, Buchli J, Chittenden M, Sykes M. Role of indirect allo- and autoreactivity in anti-tumor responses induced by recipient leukocyte infusions (RLI) in mixed chimeras prepared with nonmyeloablative conditioning. Clinical Immunology (Orlando, Fla.). 120: 33-44. PMID 16675304 DOI: 10.1016/J.Clim.2006.03.004 |
0.489 |
|
| 2006 |
Xu Y, Yang YG, Ohdan H, Ryan D, Harper D, Wu C, Kruger-Grey HS, Thall AD, Awwad M, Sykes M. Characterization of anti-Gal antibody-producing cells of baboons and humans. Transplantation. 81: 940-8. PMID 16570021 DOI: 10.1097/01.Tp.0000203300.87272.A3 |
0.369 |
|
| 2006 |
Koporc Z, Bigenzahn S, Blaha P, Fariborz E, Selzer E, Sykes M, Muehlbacher F, Wekerle T. Induction of mixed chimerism through transplantation of CD45-congenic mobilized peripheral blood stem cells after nonmyeloablative irradiation. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. 12: 284-92. PMID 16503497 DOI: 10.1016/J.Bbmt.2005.11.011 |
0.581 |
|
| 2006 |
Shimizu I, Smith NR, Zhao G, Medof E, Sykes M. Decay-accelerating factor prevents acute humoral rejection induced by low levels of anti-alphaGal natural antibodies. Transplantation. 81: 95-100. PMID 16421483 DOI: 10.1097/01.Tp.0000188176.18666.68 |
0.354 |
|
| 2006 |
Kawahara T, Shimizu I, Ohdan H, Zhao G, Sykes M. Differing mechanisms of early and late B cell hyporesponsiveness induced by mixed chimerism. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 5: 2821-9. PMID 16302994 DOI: 10.1111/J.1600-6143.2005.01121.X |
0.472 |
|
| 2006 |
Ghazi A, Griesemer A, Okumi M, Hirsh E, Lo D, Sykes M, Sachs DH, Yamada K, Huang CA. Specific Non-Responsiveness to Pig in Baboons Receiving BMT from GalT-KO Pigs. Blood. 108: 5265-5265. DOI: 10.1182/Blood.V108.11.5265.5265 |
0.457 |
|
| 2006 |
Saito TI, Sykes M. NK1.1+ Cells Are Involved in the Anti-Tumor Immunity Induced by the Rejection of Donor Hematopoietic Cells in Mixed Bone Marrow Chimeras. Blood. 108: 3166-3166. DOI: 10.1182/Blood.V108.11.3166.3166 |
0.483 |
|
| 2006 |
Andreola G, Shaffer J, Cosimi AB, Kawai T, Cotter P, Dey BR, Tolkoff-Rubin N, Preffer FI, Saidman S, Kattleman K, Sachs DH, Spitzer TR, Sykes M. Donor Specific Unresponsiveness Develops Following Loss of Chimerism in Recipients of Haploidentical Combined Bone Marrow/Kidney Transplantation but Not in Recipients of Bone Marrow Transplant Alone. Blood. 108: 3103-3103. DOI: 10.1182/Blood.V108.11.3103.3103 |
0.545 |
|
| 2006 |
Saito T, Sykes M. Long-lasting anti-tumor immunity induced by the rejection of donor hematopoietic cells in mixed bone marrow chimeras Biology of Blood and Marrow Transplantation. 12: 49. DOI: 10.1182/Blood.V106.11.1319.1319 |
0.39 |
|
| 2005 |
Yamamoto S, Lavelle JM, Vagefi PA, Arakawa H, Samelson-Jones E, Moran S, Teranishi K, Kamano C, Fishman J, Awwad M, Neville DM, Shimizu A, Sykes M, Sachs DH, Yamada K. Vascularized thymic lobe transplantation in a pig-to-baboon model: a novel strategy for xenogeneic tolerance induction and T-cell reconstitution. Transplantation. 80: 1783-90. PMID 16378075 DOI: 10.1097/01.Tp.0000184445.70285.4B |
0.515 |
|
| 2005 |
Eom HS, Rubio MT, Means TK, Luster AD, Sykes M. T-cell P/E-selectin ligand alpha(1,3)fucosylation is not required for graft-vs-host disease induction. Experimental Hematology. 33: 1564-73. PMID 16338500 DOI: 10.1016/J.Exphem.2005.08.003 |
0.384 |
|
| 2005 |
Fehr T, Bardwell PD, Sykes M. Use of skin grafting to demonstrate tolerance before kidney transplantation without immunosuppression in the recipient of a previous bone marrow transplant. Transplantation. 80: 1359-60. PMID 16314813 DOI: 10.1097/01.Tp.0000177636.84097.E1 |
0.497 |
|
| 2005 |
Rubio MT, Means TK, Chakraverty R, Shaffer J, Fudaba Y, Chittenden M, Luster AD, Sykes M. Maturation of human monocyte-derived dendritic cells (MoDCs) in the presence of prostaglandin E2 optimizes CD4 and CD8 T cell-mediated responses to protein antigens: role of PGE2 in chemokine and cytokine expression by MoDCs. International Immunology. 17: 1561-72. PMID 16303787 DOI: 10.1093/Intimm/Dxh335 |
0.435 |
|
| 2005 |
Sykes M, Spitzer TR. Protecting the host naturally. Nature Medicine. 11: 1164-5. PMID 16270073 DOI: 10.1038/Nm1105-1164 |
0.453 |
|
| 2005 |
Rodríguez-Barbosa JI, Haller GW, Zhao G, Sachs DH, Sykes M. Host thymectomy and cyclosporine lead to unstable skin graft tolerance after class I mismatched allogeneic neonatal thymic transplantation in mice. Transplant Immunology. 15: 25-33. PMID 16223670 DOI: 10.1016/J.Trim.2005.04.004 |
0.504 |
|
| 2005 |
Fehr T, Takeuchi Y, Kurtz J, Wekerle T, Sykes M. Early regulation of CD8 T cell alloreactivity by CD4+CD25- T cells in recipients of anti-CD154 antibody and allogeneic BMT is followed by rapid peripheral deletion of donor-reactive CD8+ T cells, precluding a role for sustained regulation. European Journal of Immunology. 35: 2679-90. PMID 16082727 DOI: 10.1002/Eji.200526190 |
0.76 |
|
| 2005 |
Blaha P, Bigenzahn S, Koporc Z, Sykes M, Muehlbacher F, Wekerle T. Short-term immunosuppression facilitates induction of mixed chimerism and tolerance after bone marrow transplantation without cytoreductive conditioning. Transplantation. 80: 237-43. PMID 16041269 DOI: 10.1097/01.Tp.0000164510.25625.70 |
0.479 |
|
| 2005 |
Rubio MT, Saito TI, Kattleman K, Zhao G, Buchli J, Sykes M. Mechanisms of the antitumor responses and host-versus-graft reactions induced by recipient leukocyte infusions in mixed chimeras prepared with nonmyeloablative conditioning: a critical role for recipient CD4+ T cells and recipient leukocyte infusion-derived IFN-gamma-producing CD8+ T cells. Journal of Immunology (Baltimore, Md. : 1950). 175: 665-76. PMID 16002661 DOI: 10.4049/Jimmunol.175.2.665 |
0.583 |
|
| 2005 |
Domenig C, Sanchez-Fueyo A, Kurtz J, Alexopoulos SP, Mariat C, Sykes M, Strom TB, Zheng XX. Roles of deletion and regulation in creating mixed chimerism and allograft tolerance using a nonlymphoablative irradiation-free protocol. Journal of Immunology (Baltimore, Md. : 1950). 175: 51-60. PMID 15972631 DOI: 10.4049/Jimmunol.175.1.51 |
0.763 |
|
| 2005 |
Lechler RI, Sykes M, Thomson AW, Turka LA. Organ transplantation--how much of the promise has been realized? Nature Medicine. 11: 605-13. PMID 15937473 DOI: 10.1038/Nm1251 |
0.44 |
|
| 2005 |
Sykes M, Nikolic B. Treatment of severe autoimmune disease by stem-cell transplantation. Nature. 435: 620-7. PMID 15931215 DOI: 10.1038/Nature03728 |
0.434 |
|
| 2005 |
Giovino MA, Wang H, Sykes M, Yang YG. Role of VLA-4 and VLA-5 in ex vivo maintenance of human and pig hematopoiesis in human stroma-supported long-term cultures. Experimental Hematology. 33: 363-70. PMID 15730860 DOI: 10.1016/J.Exphem.2004.11.011 |
0.351 |
|
| 2005 |
Sykes M, Shimizu I, Kawahara T. Mixed hematopoietic chimerism for the simultaneous induction of T and B cell tolerance. Transplantation. 79: S28-9. PMID 15699742 DOI: 10.1097/01.Tp.0000153296.80385.E7 |
0.473 |
|
| 2005 |
Dey BR, McAfee S, Colby C, Cieply K, Caron M, Saidman S, Preffer F, Shaffer J, Tarbell N, Sackstein R, Sachs D, Sykes M, Spitzer TR. Anti-tumour response despite loss of donor chimaerism in patients treated with non-myeloablative conditioning and allogeneic stem cell transplantation. British Journal of Haematology. 128: 351-9. PMID 15667537 DOI: 10.1111/J.1365-2141.2004.05328.X |
0.539 |
|
| 2005 |
Yamada K, Yazawa K, Shimizu A, Iwanaga T, Hisashi Y, Nuhn M, O'Malley P, Nobori S, Vagefi PA, Patience C, Fishman J, Cooper DKC, Hawley RJ, Greenstein J, Schuurman HJ, ... ... Sykes M, et al. Marked prolongation of porcine renal xenograft survival in baboons through the use of α1,3-galactosyltransferase gene-knockout donors and the cotransplantation of vascularized thymic tissue Nature Medicine. 11: 32-34. PMID 15619627 DOI: 10.1038/Nm1172 |
0.407 |
|
| 2005 |
Mapara MY, Sykes M. Induction of mixed vs full chimerism to potentiate GVL effects after bone-marrow transplantation. Methods in Molecular Medicine. 109: 469-74. PMID 15585939 DOI: 10.1385/1-59259-862-5:469 |
0.567 |
|
| 2005 |
Fehr T, Sykes M. Tolerance induction in clinical transplantation. Transplant Immunology. 13: 117-30. PMID 15380542 DOI: 10.1016/J.Trim.2004.05.009 |
0.561 |
|
| 2005 |
Kawai T, Sogawa H, Boskovic S, Abrahamian G, Smith RN, Wee SL, Andrews D, Nadazdin O, Koyama I, Sykes M, Winn HJ, Colvin RB, Sachs DH, Cosimi AB. CD154 blockade for induction of mixed chimerism and prolonged renal allograft survival in nonhuman primates. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 4: 1391-8. PMID 15307826 DOI: 10.1111/J.1600-6143.2004.00523.X |
0.519 |
|
| 2005 |
Spitzer TR, McAfee SL, Bimalangshu DR, Ballen K, Attar E, Colby C, Preffer F, Saidman S, Shaffer J, Sachs DH, Sykes M. In Vivo and Ex Vivo T-Cell Depleted (TCD) NonmyeloablativeHaploidentical Stem Cell Transplantation (NSCT) for Hematologic Malignancy (HM). Blood. 106: 5431-5431. DOI: 10.1182/Blood.V106.11.5431.5431 |
0.527 |
|
| 2005 |
Yee AJ, Spitzer TR, Saidman SL, Shaffer J, Power KA, McAfee SL, Ballen KK, Attar EC, Preffer FI, Sykes M, Dey BR. Minimal HLA Disparity and KIR Ligand Compatibility in Host Versus Graft Direction May Facilitate Donor Engraftment Following In Vivo and Ex Vivo T Cell Depleted (TCD) Nonmyeloablative Haploidentical Stem Cell Transplantation for Hematologic Malignancies. Blood. 106: 3668-3668. DOI: 10.1182/Blood.V106.11.3668.3668 |
0.545 |
|
| 2005 |
Ting DT, Dey B, Chaudhary A, Colby C, Power K, McAfee S, Ballen K, Attar E, Saidman S, Preffer F, Sackstein R, Shaffer J, Sykes M, Spitzer TR. Development of Late over Early Full Donor Chimerism (FDC) Results in Improved Progression-Free and Overall Survival in Patients with Advanced Malignant Lymphomas Receiving Nonmyeloablative Allogeneic Hematopoietic Stem Cell Transplantation (HSCT). Blood. 106: 3665-3665. DOI: 10.1182/Blood.V106.11.3665.3665 |
0.444 |
|
| 2005 |
Linden E, McAfee SL, Dey BR, Ballen K, Saidman S, Colby C, Sykes M, Spitzer TR. Outcomes of Patients with Engraftment Syndrome (ES) Following Nonmyeloablative Hematopoietic Stem Cell Transplant (SCT) for Hematologic Malignancy(HM). Blood. 106: 3661-3661. DOI: 10.1182/Blood.V106.11.3661.3661 |
0.374 |
|
| 2005 |
Shaffer JM, Villard J, Means T, Dombkowski D, Dey B, McAffee S, Ballen K, Power K, Saidman S, Preffer F, Spitzer TR, Sykes M. Fludarabine Treatment Is Associated with Depletion of Host CD4+CD25high, FOXP3+, CTLA-4+ Cells and Increased Incidences of Full Donor Chimerism and GVHD in Non-Myeloablative Haploidentical Hematopoietic Cell Transplant Recipients. Blood. 106: 2898-2898. DOI: 10.1182/Blood.V106.11.2898.2898 |
0.592 |
|
| 2005 |
Bardwell PD, Ohdan H, Sykes M. B cell tolerance and xenotransplantation Current Opinion in Organ Transplantation. 10: 252-258. DOI: 10.1097/01.Mot.0000175544.97974.92 |
0.471 |
|
| 2005 |
Chakraverty R, Buchli J, Zao G, Sykes M, Lin C. Clonal expansion but impaired trafficking of GVH-reactive T cells following delayed DLI to mixed chimeras Biology of Blood and Marrow Transplantation. 11: 10. DOI: 10.1016/J.Bbmt.2004.12.029 |
0.389 |
|
| 2005 |
Chakraverty R, Buchli J, Zhao G, Hsu R, Croft M, Sykes M. Sequential blockade and engagement of costimulatory pathways: A potential strategy for amplifying graft-versus-leukemia responses without graft-versus-host disease Biology of Blood and Marrow Transplantation. 11: 10. DOI: 10.1016/J.Bbmt.2004.12.028 |
0.383 |
|
| 2004 |
Eguchi H, Knosalla C, Lan P, Cheng J, Diouf B, Wang L, Abe M, Schuurman HJ, Sachs DH, Sykes M, Cooper DK, Yang YG. T cells from presensitized donors fail to cause graft-versus-host disease in a pig-to-mouse xenotransplantation model. Transplantation. 78: 1609-17. PMID 15591949 DOI: 10.1097/01.Tp.0000142621.52211.79 |
0.552 |
|
| 2004 |
Kurtz J, Wekerle T, Sykes M. Tolerance in mixed chimerism - a role for regulatory cells? Trends in Immunology. 25: 518-23. PMID 15364053 DOI: 10.1016/J.It.2004.08.007 |
0.757 |
|
| 2004 |
Yang YG, Wood JC, Lan P, Wilkinson RA, Sykes M, Fishman JA, Patience C. Mouse retrovirus mediates porcine endogenous retrovirus transmission into human cells in long-term human-porcine chimeric mice. The Journal of Clinical Investigation. 114: 695-700. PMID 15343388 DOI: 10.1172/Jci21946 |
0.396 |
|
| 2004 |
Wekerle T, Sykes M. Induction of tolerance. Surgery. 135: 359-64. PMID 15041958 DOI: 10.1016/J.Surg.2003.10.010 |
0.315 |
|
| 2004 |
Mapara MY, Sykes M. Tolerance and cancer: mechanisms of tumor evasion and strategies for breaking tolerance. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 22: 1136-51. PMID 15020616 DOI: 10.1200/Jco.2004.10.041 |
0.425 |
|
| 2004 |
Kurtz J, Shaffer J, Lie A, Anosova N, Benichou G, Sykes M. Mechanisms of early peripheral CD4 T-cell tolerance induction by anti-CD154 monoclonal antibody and allogeneic bone marrow transplantation: evidence for anergy and deletion but not regulatory cells. Blood. 103: 4336-43. PMID 14962909 DOI: 10.1182/Blood-2003-08-2642 |
0.789 |
|
| 2004 |
Nikolic B, Takeuchi Y, Leykin I, Fudaba Y, Smith RN, Sykes M. Mixed hematopoietic chimerism allows cure of autoimmune diabetes through allogeneic tolerance and reversal of autoimmunity. Diabetes. 53: 376-83. PMID 14747288 DOI: 10.2337/Diabetes.53.2.376 |
0.457 |
|
| 2004 |
Lan P, Wang L, Diouf B, Eguchi H, Su H, Bronson R, Sachs DH, Sykes M, Yang YG. Induction of human T-cell tolerance to porcine xenoantigens through mixed hematopoietic chimerism. Blood. 103: 3964-9. PMID 14739221 DOI: 10.1182/Blood-2003-10-3697 |
0.509 |
|
| 2004 |
Takeuchi Y, Ito H, Kurtz J, Wekerle T, Ho L, Sykes M. Earlier low-dose TBI or DST overcomes CD8+ T-cell-mediated alloresistance to allogeneic marrow in recipients of anti-CD40L. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 4: 31-40. PMID 14678032 DOI: 10.1046/J.1600-6135.2003.00272.X |
0.783 |
|
| 2004 |
Sykes M. JAKing up immunosuppression. Nature Medicine. 9: 1458-9. PMID 14647518 DOI: 10.1038/Nm1203-1458 |
0.44 |
|
| 2004 |
Kawahara T, Ohdan H, Zhao G, Yang YG, Sykes M. Peritoneal cavity B cells are precursors of splenic IgM natural antibody-producing cells. Journal of Immunology (Baltimore, Md. : 1950). 171: 5406-14. PMID 14607944 DOI: 10.4049/Jimmunol.171.10.5406 |
0.362 |
|
| 2004 |
Kim YM, Mapara MY, Down JD, Johnson KW, Boisgerault F, Akiyama Y, Benichou G, Pelot M, Zhao G, Sykes M. Graft-versus-host-reactive donor CD4 cells can induce T cell-mediated rejection of the donor marrow in mixed allogeneic chimeras prepared with nonmyeloablative conditioning. Blood. 103: 732-9. PMID 14512313 DOI: 10.1182/Blood-2003-02-0643 |
0.621 |
|
| 2004 |
Kurtz J, Lie A, Griffith M, Eysaman S, Shaffer J, Anosova N, Turka L, Benichou G, Sykes M. Lack of role for CsA-sensitive or Fas pathways in the tolerization of CD4 T cells via BMT and anti-CD40L. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 3: 804-16. PMID 12814472 DOI: 10.1034/J.1600-6143.2003.00128.X |
0.799 |
|
| 2004 |
Chakraverty R, Buchli J, Zhao G, Sykes M. Proliferation, Expansion, Effector Differentiation and Survival of GVH-Reactive T Cells Following Delayed DLI to Mixed Chimeras. Blood. 104: 594-594. DOI: 10.1182/Blood.V104.11.594.594 |
0.543 |
|
| 2004 |
Chakraverty R, Buchli J, Zhao G, Hsu R, Croft M, Sykes M. Sequential Blockade and Engagement of Co-Stimulatory Pathways: A Potential Strategy for Amplifying Graft-Versus-Leukemia Responses without GVHD. Blood. 104: 3075-3075. DOI: 10.1182/blood.v104.11.3075.3075 |
0.471 |
|
| 2004 |
Chakraverty R, Buchli J, Zhao G, Hsu R, Sykes M. Host Environment Dictates the Outcome Following Transfer of Graft-Versus-Host Reactive Effector/Memory T Cells. Blood. 104: 3046-3046. DOI: 10.1182/Blood.V104.11.3046.3046 |
0.549 |
|
| 2004 |
Eom H, Chakraverty R, Sachs J, Zhao G, Sykes M. Requirement for CD4 Help for Optimal GVL Effects of Alloreactive T Cells Given to Established Mixed Chimeras but Not Freshly Irradiated Mice. Blood. 104: 3044-3044. DOI: 10.1182/Blood.V104.11.3044.3044 |
0.555 |
|
| 2004 |
Saito TI, Rubio MT, Sykes M. Clinical Relevance of Recipient Leukocyte Infusion (RLI) Therapy. Blood. 104: 2120-2120. DOI: 10.1182/Blood.V104.11.2120.2120 |
0.458 |
|
| 2004 |
Takeuchi Y, Nikolic B, Sykes M. T CELL-DEPLETED ALLOGENEIC BONE MARROW TRANSPLANTATION (BMT) INDUCES MIXED CHIMERISM AND DONOR - SPECIFIC TOLERANCE AND PREVENTS DIABETES IN NOD MICE RECEIVING LOW-DOSE (4 GY) TOTAL BODY IRRADIATION (TBI), CD8 T CELL DEPLETION, AND ANTI-CD40LMAB. Transplantation. 78: 432. DOI: 10.1097/00007890-200407271-01158 |
0.49 |
|
| 2004 |
Yamada K, Yazawa K, Shimizu A, Nuhn M, Moran S, Hisashi Y, Nobori S, Fishman J, Cooper DK, Hawley R, Patience C, Greenstein J, Schuurman H, Sykes M, Sachs DH. CO-TRANSPLANTING A VASCULARIZED DONOR THYMIC GRAFT AND LIFE-SUPPORTING KIDNEY USING GALT-KO DONORS IN BABOONS Transplantation. 78: 157. DOI: 10.1097/00007890-200407271-00415 |
0.46 |
|
| 2004 |
Ito H, Kurtz J, Shaffer J, Sykes M. ANTI-CD40L MAB OVERCOMES CD4 T CELL-MEDIATED RESISTANCE TO XENOGENEIC MARROW ENGRAFTMENT Transplantation. 78: 156-157. DOI: 10.1097/00007890-200407271-00413 |
0.719 |
|
| 2004 |
Koporc Z, Bigenzahn S, Blaha P, Muehlbacher F, Sykes M, Wekerle T. THE USE OF MOBILIZED PERIPHERAL BLOOD STEM CELLS FOR THE INDUCTION OF MIXED CHIMERISM AND TOLERANCE Transplantation. 78: 131. DOI: 10.1097/00007890-200407271-00349 |
0.345 |
|
| 2004 |
Boskovic S, Kawai T, Wee SL, Nadazdin O, Koyama I, Smith RN, Elias N, Ochiai T, Sykes M, Colvin RB, Sachs DH, Cosimi AB. LONG TERM OBSERVATIONS IN RENAL ALLOGRAFT RECIPIENTS TREATED WITH A CHIMERISM- INDUCING NONMYELOABLATIVE REGIMEN WITH CD154 BLOCKADE Transplantation. 78: 43. DOI: 10.1097/00007890-200407271-00124 |
0.424 |
|
| 2004 |
Blaha P, Bigenzahn S, Koporc Z, Muehlbacher F, Sykes M, Wekerle T. SHORT-COURSE IMMUNOSUPPRESSION FACILITATES CHIMERISM AND TOLERANCE IN A NON-CYTOREDUCTIVE MODEL USING BMT AND COSTIMULATION BLOCKADEANONE MARROW TRANSPLANTATION Transplantation. 78: 41-42. DOI: 10.1097/00007890-200407271-00121 |
0.497 |
|
| 2004 |
Fehr T, Takeuchi Y, Kurtz J, Sykes M. CD8+ T CELL TOLERANCE AFTER BONE MARROW TRANSPLANTATION USING NON-MYELOABLATIVE CONDITIONING WITH TBI AND ANTI-CD154 MAB: IMPORTANCE OF SIGNAL 1, CD4+ T CELLS AND CTLA4, BUT NO EVIDENCE FOR LONG-TERM REGULATION Transplantation. 78: 41. DOI: 10.1097/00007890-200407271-00120 |
0.767 |
|
| 2003 |
Ito H, Takeuchi Y, Shaffer J, Sykes M. Local irradiation enhances congenic donor pluripotent hematopoietic stem cell engraftment similarly in irradiated and nonirradiated sites. Blood. 103: 1949-54. PMID 14592817 DOI: 10.1182/Blood-2003-09-3249 |
0.453 |
|
| 2003 |
Koenecke C, Shaffer J, Alexander SI, Preffer F, Dombkowski D, Saidman SL, Dey B, McAfee S, Spitzer TR, Sykes M. NK cell recovery, chimerism, function, and recognition in recipients of haploidentical hematopoietic cell transplantation following nonmyeloablative conditioning using a humanized anti-CD2 mAb, Medi-507 Experimental Hematology. 31: 911-923. PMID 14550807 DOI: 10.1016/S0301-472X(03)00224-8 |
0.577 |
|
| 2003 |
Le Guern AC, Giovino MA, Abe M, Theodore PR, Qi J, Down JD, Sachs DH, Sykes M, Yang YG. Stem cell activity of porcine c-kit+ hematopoietic cells. Experimental Hematology. 31: 833-40. PMID 12962730 DOI: 10.1016/S0301-472X(03)00197-8 |
0.396 |
|
| 2003 |
Mapara MY, Kim YM, Marx J, Sykes M. Donor lymphocyte infusion-mediated graft-versus-leukemia effects in mixed chimeras established with a nonmyeloablative conditioning regimen: extinction of graft-versus-leukemia effects after conversion to full donor chimerism. Transplantation. 76: 297-305. PMID 12883182 DOI: 10.1097/01.Tp.0000072014.83469.2D |
0.471 |
|
| 2003 |
Kraus AB, Shaffer J, Toh HC, Preffer F, Dombkowski D, Saidman S, Colby C, George R, McAfee S, Sackstein R, Dey B, Spitzer TR, Sykes M. Early host CD8 T-cell recovery and sensitized anti-donor interleukin-2-producing and cytotoxic T-cell responses associated with marrow graft rejection following nonmyeloablative allogeneic bone marrow transplantation Experimental Hematology. 31: 609-621. PMID 12842706 DOI: 10.1016/S0301-472X(03)00082-1 |
0.584 |
|
| 2003 |
Daly AS, McAfee S, Dey B, Colby C, Schulte L, Yeap B, Sackstein R, Tarbell NJ, Sachs D, Sykes M, Spitzer TR. Nonmyeloablative bone marrow transplantation: Infectious complications in 65 recipients of HLA-identical and mismatched transplants Biology of Blood and Marrow Transplantation. 9: 373-382. PMID 12813445 DOI: 10.1016/S1083-8791(03)00100-9 |
0.479 |
|
| 2003 |
Zhao Y, Rodriguez-Barbosa JI, Shimizu A, Sachs DH, Sykes M. Despite efficient intrathymic negative selection of host-reactive T cells, autoimmune disease may develop in porcine thymus-grafted athymic mice: evidence for failure of regulatory mechanisms suppressing autoimmunity. Transplantation. 75: 1832-40. PMID 12811242 DOI: 10.1097/01.Tp.0000065292.20062.F0 |
0.486 |
|
| 2003 |
Rubio MT, Kim YM, Sachs T, Mapara M, Zhao G, Sykes M. Antitumor effect of donor marrow graft rejection induced by recipient leukocyte infusions in mixed chimeras prepared with nonmyeloablative conditioning: critical role for recipient-derived IFN-gamma. Blood. 102: 2300-7. PMID 12791660 DOI: 10.1182/Blood-2002-12-3949 |
0.503 |
|
| 2003 |
Spitzer TR, McAfee SL, Dey BR, Colby C, Hope J, Grossberg H, Preffer F, Shaffer J, Alexander SI, Sachs DH, Sykes M. Nonmyeloablative haploidentical stem-cell transplantation using anti-CD2 monoclonal antibody (MEDI-507)-based conditioning for refractory hematologic malignancies. Transplantation. 75: 1748-51. PMID 12777868 DOI: 10.1097/01.Tp.0000064211.23536.Ad |
0.57 |
|
| 2003 |
Barth RN, Yamamoto S, LaMattina JC, Kumagai N, Kitamura H, Vagefi PA, Awwad M, Colvin RB, Cooper DK, Sykes M, Sachs DH, Yamada K. Xenogeneic thymokidney and thymic tissue transplantation in a pig-to-baboon model: I. Evidence for pig-specific T-cell unresponsiveness. Transplantation. 75: 1615-24. PMID 12777846 DOI: 10.1097/01.Tp.0000064335.50622.20 |
0.507 |
|
| 2003 |
Dey BR, McAfee S, Colby C, Sackstein R, Saidman S, Tarbell N, Sachs DH, Sykes M, Spitzer TR. Impact of prophylactic donor leukocyte infusions on mixed chimerism, graft-versus-host disease, and antitumor response in patients with advanced hematologic malignancies treated with nonmyeloablative conditioning and allogeneic bone marrow transplantation Biology of Blood and Marrow Transplantation. 9: 320-329. PMID 12766882 DOI: 10.1016/S1083-8791(03)00077-6 |
0.532 |
|
| 2003 |
Zhao Y, Ohdan H, Manilay JO, Sykes M. NK cell tolerance in mixed allogeneic chimeras. Journal of Immunology (Baltimore, Md. : 1950). 170: 5398-405. PMID 12759414 DOI: 10.4049/Jimmunol.170.11.5398 |
0.455 |
|
| 2003 |
Kim YM, Sachs T, Asavaroengchai W, Bronson R, Sykes M. Graft-versus-host disease can be separated from graft-versus-lymphoma effects by control of lymphocyte trafficking with FTY720. The Journal of Clinical Investigation. 111: 659-69. PMID 12618520 DOI: 10.1172/Jci16950 |
0.496 |
|
| 2003 |
Wu A, Yamada K, Neville DM, Awwad M, Wain JC, Shimizu A, Gojo S, Kitamura H, Colvin RB, Cooper DK, Sykes M, Sachs DH. Xenogeneic thymus transplantation in a pig-to-baboon model. Transplantation. 75: 282-91. PMID 12589146 DOI: 10.1097/01.Tp.0000044137.97841.99 |
0.457 |
|
| 2003 |
Ohdan H, Sykes M. B cell tolerance to xenoantigens. Xenotransplantation. 10: 98-106. PMID 12588643 DOI: 10.1034/J.1399-3089.2003.02108.X |
0.468 |
|
| 2003 |
Rodriguez-Barbosa JI, Zhao Y, Houser S, Zhao G, Sykes M. Fetal porcine thymus engraftment, survival and CD4 reconstitution in alphaGal-KO mice is impaired in the presence of high levels of antibodies against alphaGal. Xenotransplantation. 10: 24-40. PMID 12535223 DOI: 10.1034/J.1399-3089.2003.01104.X |
0.504 |
|
| 2003 |
Rodriguez-Barbosa JI, Zhao Y, Zhao G, Ezquerra A, Sykes M. Murine CD4 T cells selected in a highly disparate xenogeneic porcine thymus graft do not show rapid decay in the absence of selecting MHC in the periphery. Journal of Immunology (Baltimore, Md. : 1950). 169: 6697-710. PMID 12471101 DOI: 10.4049/Jimmunol.169.12.6697 |
0.554 |
|
| 2003 |
Preffer FI, Dombkowski D, Sykes M, Scadden D, Yang YG. Lineage-negative side-population (SP) cells with restricted hematopoietic capacity circulate in normal human adult blood: immunophenotypic and functional characterization. Stem Cells (Dayton, Ohio). 20: 417-27. PMID 12351812 DOI: 10.1634/Stemcells.20-5-417 |
0.41 |
|
| 2003 |
Wekerle T, Kurtz J, Bigenzahn S, Takeuchi Y, Sykes M. Mechanisms of transplant tolerance induction using costimulatory blockade. Current Opinion in Immunology. 14: 592-600. PMID 12183158 DOI: 10.1016/S0952-7915(02)00378-3 |
0.73 |
|
| 2003 |
Mapara MY, Pelot M, Zhao G, Swenson K, Pearson D, Sykes M. Induction of stable long-term mixed hematopoietic chimerism following nonmyeloablative conditioning with T cell-depleting antibodies, cyclophosphamide, and thymic irradiation leads to donor-specific in vitro and in vivo tolerance. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. 7: 646-55. PMID 11787527 DOI: 10.1053/Bbmt.2001.V7.Pm11787527 |
0.526 |
|
| 2003 |
Sykes M, Garrigue V, Johnson RP, Nikolic B, Rodriguez-Barbosa JI, Rosenzweig M, Sachs DH, Wu A, Yamada K, Zhao Y. Xenogeneic thymic replacement to achieve immune restoration in HIV infection Clinical and Applied Immunology Reviews. 3: 167-171. DOI: 10.1016/S1529-1049(02)00160-5 |
0.461 |
|
| 2002 |
Toh HC, Spitzer TR, Preffer F, Alexander SI, McAfee S, Dombkowski D, Clark JS, Colby C, Saidman S, Sackstein R, Sykes M. Fluctuating lymphocyte chimerism, tolerance and anti-tumor response in a patient with refractory lymphoma receiving non-myeloablative conditioning and a haploidentical related allogeneic bone marrow transplant Cytokines, Cellular and Molecular Therapy. 7: 43-47. PMID 12607794 DOI: 10.1080/13684730412331302054 |
0.5 |
|
| 2002 |
Blaha P, Bigenzahn S, Koporc Z, Schmid M, Langer F, Selzer E, Bergmeister H, Wrba F, Kurtz J, Kiss C, Roth E, Muehlbacher F, Sykes M, Wekerle T. The influence of immunosuppressive drugs on tolerance induction through bone marrow transplantation with costimulation blockade. Blood. 101: 2886-93. PMID 12433677 DOI: 10.1182/Blood-2002-10-3014 |
0.764 |
|
| 2002 |
Mapara MY, Kim YM, Wang SP, Bronson R, Sachs DH, Sykes M. Donor lymphocyte infusions mediate superior graft-versus-leukemia effects in mixed compared to fully allogeneic chimeras: a critical role for host antigen-presenting cells. Blood. 100: 1903-9. PMID 12176915 DOI: 10.1182/Blood-2002-01-0023 |
0.545 |
|
| 2002 |
Heinz M, Huang CA, Emery DW, Giovino MA, LeGuern A, Kurilla-Mahon B, Theodore P, Arn JS, Sykes M, Mulligan R, Down JD, Sachs DH, Goodell MA. Use of CD9 expression to enrich for porcine hematopoietic progenitors. Experimental Hematology. 30: 809-15. PMID 12135680 DOI: 10.1016/S0301-472X(02)00835-4 |
0.439 |
|
| 2002 |
Kurtz J, Ito H, Wekerle T, Shaffer J, Sykes M. Mechanisms involved in the establishment of tolerance through costimulatory blockade and BMT: lack of requirement for CD40L-mediated signaling for tolerance or deletion of donor-reactive CD4+ cells. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 1: 339-49. PMID 12099378 DOI: 10.1034/J.1600-6143.2001.10409.X |
0.799 |
|
| 2002 |
Theodore PR, Simon AR, Warrens AN, Sackstein R, Sykes M. Porcine mononuclear cells adhere to human fibronectin independently of very late antigen-5: implications for donor-specific tolerance induction in xenotransplantation. Xenotransplantation. 9: 277-89. PMID 12060464 DOI: 10.1034/J.1399-3089.2002.01086.X |
0.432 |
|
| 2002 |
Wekerle T, Nikolic B, Pearson DA, Swenson KG, Sykes M. Minimal conditioning required in a murine model of T cell depletion, thymic irradiation and high-dose bone marrow transplantation for the induction of mixed chimerism and tolerance Transplant International. 15: 248-253. PMID 12012046 DOI: 10.1007/S00147-002-0411-3 |
0.485 |
|
| 2002 |
Yang YG, Qi J, Wang MG, Sykes M. Donor-derived interferon gamma separates graft-versus-leukemia effects and graft-versus-host disease induced by donor CD8 T cells. Blood. 99: 4207-15. PMID 12010827 DOI: 10.1182/Blood.V99.11.4207 |
0.587 |
|
| 2002 |
Abe M, Qi J, Sykes M, Yang YG. Mixed chimerism induces donor-specific T-cell tolerance across a highly disparate xenogeneic barrier. Blood. 99: 3823-9. PMID 11986242 DOI: 10.1182/Blood.V99.10.3823 |
0.534 |
|
| 2002 |
Sykes M, Spitzer TR. Non-myeloblative induction of mixed hematopoietic chimerism: application to transplantation tolerance and hematologic malignancies in experimental and clinical studies. Cancer Treatment and Research. 110: 79-99. PMID 11908201 DOI: 10.1007/978-1-4615-0919-6_4 |
0.527 |
|
| 2002 |
Giovino MA, Down JD, Jackson JD, Sykes M, Monroy RL, White-Scharf ME. Porcine hematopoiesis on primate stroma in long-term cultures: enhanced growth with neutralizing tumor necrosis factor-alpha and tumor growth factor-beta antibodies. Transplantation. 73: 723-31. PMID 11907417 DOI: 10.1097/00007890-200203150-00011 |
0.436 |
|
| 2002 |
Bühler L, Awwad M, Treter S, Chang Q, Basker M, Alwayn IP, Teranishi K, Ericsson T, Moran K, Harper D, Kurilla-Mahon B, Huang CA, Sackstein R, Sykes M, White-Scharf ME, et al. Pig hematopoietic cell chimerism in baboons conditioned with a nonmyeloablative regimen and CD154 blockade. Transplantation. 73: 12-22. PMID 11792972 DOI: 10.1097/00007890-200201150-00004 |
0.537 |
|
| 2002 |
Abe M, Cheng J, Qi J, Glaser RM, Thall AD, Sykes M, Yang YG. Elimination of porcine hemopoietic cells by macrophages in mice. Journal of Immunology (Baltimore, Md. : 1950). 168: 621-8. PMID 11777954 DOI: 10.4049/Jimmunol.168.2.621 |
0.459 |
|
| 2002 |
Ohdan H, Swenson KG, Kitamura H, Yang YG, Sykes M. Tolerization of Gal alpha 1,3Gal-reactive B cells in pre-sensitized alpha 1,3-galactosyltransferase-deficient mice by nonmyeloablative induction of mixed chimerism. Xenotransplantation. 8: 227-38. PMID 11737848 DOI: 10.1034/J.1399-3089.2001.00006.X |
0.497 |
|
| 2002 |
Yang Y, Sykes M. Graft-versus-Host Disease and Graft-versus-Leukemic Effect in Allogeneic Bone Marrow Transplantation Graft. 5: 250-255. DOI: 10.1177/152216280200500408 |
0.369 |
|
| 2002 |
Blaha P, Kiss C, Langer F, Selzer E, Bergmeister H, Kurtz J, Roth E, Muehlbacher F, Sykes M, Wekerle T. The effects of rapamycin and cyclosporin a on tolerance induction through bone marrow transplantation with costimulation blockade Journal of Heart and Lung Transplantation. 21: 155. DOI: 10.1016/S1053-2498(01)00712-4 |
0.736 |
|
| 2001 |
Dey BR, McAfee S, Sackstein R, Colby C, Saidman S, Weymouth D, Poliquin C, Vanderklish J, Sachs DH, Sykes M, Spitzer TR. Successful allogeneic stem cell transplantation with nonmyeloablative conditioning in patients with relapsed hematologic malignancy following autologous stem cell transplantation Biology of Blood and Marrow Transplantation. 7: 604-612. PMID 11760148 DOI: 10.1053/Bbmt.2001.V7.Pm11760148 |
0.446 |
|
| 2001 |
Zhao Y, Rodriguez-Barbosa JI, Swenson K, Zhao G, Arn JS, Sykes M. Highly disparate xenogeneic skin graft tolerance induction by fetal pig thymus in thymectomized mice: Conditioning requirements and the role of coimplantation of fetal pig liver. Transplantation. 72: 1608-15. PMID 11726819 DOI: 10.1097/00007890-200111270-00006 |
0.378 |
|
| 2001 |
Russell PS, Chase CM, Sykes M, Ito H, Shaffer J, Colvin RB. Tolerance, mixed chimerism, and chronic transplant arteriopathy Journal of Immunology. 167: 5731-5740. PMID 11698446 DOI: 10.4049/Jimmunol.167.10.5731 |
0.591 |
|
| 2001 |
Rodriguez-Barbosa JI, Zhao Y, Barth R, Zhao G, Arn JS, Sachs DH, Sykes M. Enhanced CD4 reconstitution by grafting neonatal porcine tissue in alternative locations is associated with donor-specific tolerance and suppression of preexisting xenoreactive T cells. Transplantation. 72: 1223-31. PMID 11602846 DOI: 10.1097/00007890-200110150-00007 |
0.441 |
|
| 2001 |
Kawai T, Sogawa H, Koulmanda M, Smith RN, O'Neil JJ, Wee SL, Boskovic S, Sykes M, Colvin RB, Sachs DH, Auchincloss H, Cosimi AB, C Ko DS. Long-term islet allograft function in the absence of chronic immunosuppression: a case report of a nonhuman primate previously made tolerant to a renal allograft from the same donor. Transplantation. 72: 351-4. PMID 11477369 DOI: 10.1097/00007890-200107270-00036 |
0.393 |
|
| 2001 |
Ohdan H, Yang YG, Swenson KG, Kitamura H, Sykes M. T cell and B cell tolerance to GALalpha1,3GAL-expressing heart xenografts is achieved in alpha1,3-galactosyltransferase-deficient mice by nonmyeloablative induction of mixed chimerism. Transplantation. 71: 1532-42. PMID 11435961 DOI: 10.1097/00007890-200106150-00009 |
0.47 |
|
| 2001 |
Sykes M, Sachs DH. Mixed chimerism. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 356: 707-26. PMID 11375074 DOI: 10.1098/rstb.2001.0853 |
0.424 |
|
| 2001 |
Sykes M. Mixed chimerism and transplant tolerance. Immunity. 14: 417-24. PMID 11336687 DOI: 10.1016/S1074-7613(01)00122-4 |
0.45 |
|
| 2001 |
Nikolic B, Khan A, Sykes M. Induction of tolerance by mixed chimerism with nonmyeloblative host conditioning: the importance of overcoming intrathymic alloresistance. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. 7: 144-53. PMID 11302548 DOI: 10.1053/Bbmt.2001.V7.Pm11302548 |
0.522 |
|
| 2001 |
Wu A, Yamada K, Awwad M, Kitamura H, Wain J, Neville DM, Cooper DKC, Sykes M, Sachs DH. Effects of xenogeneic thymic transplantation in baboons. Transplantation Proceedings. 33: 766. PMID 11267060 DOI: 10.1016/S0041-1345(00)02244-2 |
0.475 |
|
| 2001 |
Nikolic B, Zhao G, Sykes M. A role for donor-derived B cells but not T cells in the maintenance of mixed hematopoietic chimerism. Transplantation Proceedings. 33: 182. PMID 11266770 DOI: 10.1016/S0041-1345(00)01966-7 |
0.537 |
|
| 2001 |
Ito H, Kurtz J, Shaffer J, Sykes M. CD4 T cell-mediated alloresistance to fully MHC-mismatched allogeneic bone marrow engraftment is dependent on CD40-CD40 ligand interactions, and lasting T cell tolerance is induced by bone marrow transplantation with initial blockade of this pathway. Journal of Immunology (Baltimore, Md. : 1950). 166: 2970-81. PMID 11207246 DOI: 10.4049/Jimmunol.166.5.2970 |
0.774 |
|
| 2001 |
Burk RD, Poller DN, Spitzer TR, Sykes M, Childs R, Barrett AJ, Linehan WM. Treatment of renal-cell cancer by transplantation of allogeneic stem cells [1] (multiple letters) New England Journal of Medicine. 344: 137-138. PMID 11188409 DOI: 10.1056/NEJM200101113440211 |
0.305 |
|
| 2001 |
Wekerle T, Sykes M. Mixed chimerism and transplantation tolerance. Annual Review of Medicine. 52: 353-70. PMID 11160784 DOI: 10.1146/Annurev.Med.52.1.353 |
0.473 |
|
| 2001 |
Wekerle T, Kurtz J, Sayegh M, Ito H, Wells A, Bensinger S, Shaffer J, Turka L, Sykes M. Peripheral deletion after bone marrow transplantation with costimulatory blockade has features of both activation-induced cell death and passive cell death. Journal of Immunology (Baltimore, Md. : 1950). 166: 2311-6. PMID 11160287 DOI: 10.4049/Jimmunol.166.4.2311 |
0.774 |
|
| 2001 |
Nikolic B, Cooke DT, Zhao G, Sykes M. Both gamma delta T cells and NK cells inhibit the engraftment of xenogeneic rat bone marrow cells and the induction of xenograft tolerance in mice. Journal of Immunology (Baltimore, Md. : 1950). 166: 1398-404. PMID 11145725 DOI: 10.4049/Jimmunol.166.2.1398 |
0.53 |
|
| 2001 |
Sykes M. Graft-versus-host alloresponses to treat nonlymphohematopoietic tumors: is there a solid approach? Journal of Immunotherapy. 24: 101-103. DOI: 10.1097/00002371-200103000-00002 |
0.316 |
|
| 2000 |
Ohdan H, Swenson KG, Kruger Gray HS, Yang YG, Xu Y, Thall AD, Sykes M. Mac-1-negative B-1b phenotype of natural antibody-producing cells, including those responding to Gal alpha 1,3Gal epitopes in alpha 1,3-galactosyltransferase-deficient mice. Journal of Immunology (Baltimore, Md. : 1950). 165: 5518-29. PMID 11067905 DOI: 10.4049/Jimmunol.165.10.5518 |
0.393 |
|
| 2000 |
Zhao Y, Swenson K, Wekerle T, Rodriguez-Barbosa JI, Arn JS, Sykes M. The critical role of mouse CD4+ cells in the rejection of highly disparate xenogeneic pig thymus grafts. Xenotransplantation. 7: 129-37. PMID 10961297 DOI: 10.1034/J.1399-3089.2000.00048.X |
0.566 |
|
| 2000 |
Bühler L, Awwad M, Basker M, Gojo S, Thall A, Down JD, Sykes M, Andrews D, Sackstein R, White-Scharf ME, Sachs DH, Cooper DK. A nonmyeloablative regimen with CD40L blockade leads to humoral and cellular hyporesponsiveness to pig hematopoietic cells in baboons. Transplantation Proceedings. 32: 1100. PMID 10936377 DOI: 10.1016/S0041-1345(00)01142-8 |
0.428 |
|
| 2000 |
Wu A, Yamada K, Awwad M, Shimizu A, Watts A, Murphy M, Gojo S, Neville D, Cooper DKC, Sykes M, Sachs DH. Experience with porcine thymic transplantation in baboons. Transplantation Proceedings. 32: 1048. PMID 10936347 DOI: 10.1016/S0041-1345(00)01113-1 |
0.449 |
|
| 2000 |
Chen AM, Zhou Y, Swenson K, Sachs DH, Sykes M, Yang YG. Porcine stem cell engraftment and seeding of murine thymus with class II+ cells in mice expressing porcine cytokines: toward tolerance induction across discordant xenogeneic barriers. Transplantation. 69: 2484-90. PMID 10910267 DOI: 10.1097/00007890-200006270-00005 |
0.493 |
|
| 2000 |
Spitzer TR, McAfee S, Sackstein R, Colby C, Toh HC, Mulkani P, Saidman S, Weymouth D, Preffer F, Poliquin C, Foley A, Cox B, Andrews D, Sachs DH, Sykes M. Intentional Induction of Mixed Chimerism and Achievement of Antitumor Responses after Nonmyeloablative Conditioning Therapy and HLA-Matched Donor Bone Marrow Transplantation for Refractory Hematologic Malignancies Biology of Blood and Marrow Transplantation. 6: 309-320. PMID 10905768 DOI: 10.1016/S1083-8791(00)70056-5 |
0.475 |
|
| 2000 |
Bühler L, Awwad M, Basker M, Gojo S, Watts A, Treter S, Nash K, Oravec G, Chang Q, Thall A, Down JD, Sykes M, Andrews D, Sackstein R, White-Scharf ME, et al. High-dose porcine hematopoietic cell transplantation combined with CD40 ligand blockade in baboons prevents an induced anti-pig humoral response. Transplantation. 69: 2296-304. PMID 10868629 DOI: 10.1097/00007890-200006150-00013 |
0.484 |
|
| 2000 |
Fuchimoto Y, Huang CA, Yamada K, Shimizu A, Kitamura H, Colvin RB, Ferrara V, Murphy MC, Sykes M, White-Scharf M, Neville DM, Sachs DH. Mixed chimerism and tolerance without whole body irradiation in a large animal model. The Journal of Clinical Investigation. 105: 1779-89. PMID 10862793 DOI: 10.1172/Jci8721 |
0.531 |
|
| 2000 |
Yang YG, Chen AM, Garrett LJ, Sergio JJ, Theodore P, Awwad M, VerHalen J, Bodine DM, Sachs DH, Sykes M. Development and analysis of transgenic mice expressing porcine hematopoietic cytokines: A model for achieving, durable porcine hematopoietic chimerism across an extensive xenogeneic barrier Xenotransplantation. 7: 58-64. PMID 10809058 DOI: 10.1034/J.1399-3089.2000.00044.X |
0.325 |
|
| 2000 |
Zhao Y, Rodriguez-Barbosa JI, Swenson K, Barth RN, Shimizu A, Arn JS, Sachs DH, Sykes M. The induction of specific pig skin graft tolerance by grafting with neonatal pig thymus in thymectomized mice. Transplantation. 69: 1447-51. PMID 10798769 DOI: 10.1097/00007890-200004150-00040 |
0.307 |
|
| 2000 |
Nikolic B, Lee S, Bronson RT, Grusby MJ, Sykes M. Th1 and Th2 mediate acute graft-versus-host disease, each with distinct end-organ targets Journal of Clinical Investigation. 105: 1289-1298. PMID 10792004 DOI: 10.1172/Jci7894 |
0.43 |
|
| 2000 |
Ohdan H, Yang YG, Swenson KG, Thall AD, Sykes M. In vivo T-cell depletion enhances production of anti-GALalpha1,3GAL natural antibodies in alpha1,3-galactosyltransferase-deficient mice. Transplantation. 69: 910-3. PMID 10755549 DOI: 10.1097/00007890-200003150-00041 |
0.399 |
|
| 2000 |
Wekerle T, Kurtz J, Ito H, Ronquillo JV, Dong V, Zhao G, Shaffer J, Sayegh MH, Sykes M. Allogeneic bone marrow transplantation with co-stimulatory blockade induces macrochimerism and tolerance without cytoreductive host treatment. Nature Medicine. 6: 464-9. PMID 10742157 DOI: 10.1038/74731 |
0.772 |
|
| 2000 |
Cheng T, Rodrigues N, Shen H, Yang Y, Dombkowski D, Sykes M, Scadden DT. Hematopoietic stem cell quiescence maintained by p21cip1/waf1. Science (New York, N.Y.). 287: 1804-8. PMID 10710306 DOI: 10.1126/Science.287.5459.1804 |
0.389 |
|
| 2000 |
Warrens AN, Simon AR, Theodore PR, Sachs DH, Sykes M. Cross-species compatibility of intercellular adhesion molecule-1 (CD54) with its ligands. Transplantation. 69: 394-9. PMID 10706049 DOI: 10.1097/00007890-200002150-00015 |
0.396 |
|
| 2000 |
Kozlowski T, Sablinski T, Basker M, Kitamura H, Spitzer TR, Fishman J, Sykes M, Cooper DK, Sachs DH. Decreased graft-versus-host disease after haplotype mismatched bone marrow allografts in miniature swine following interleukin-2 treatment. Bone Marrow Transplantation. 25: 47-52. PMID 10654014 DOI: 10.1038/Sj.Bmt.1702083 |
0.451 |
|
| 2000 |
Yang YG, Chen AM, Sergio JJ, Zhou Y, Sykes M. Role of antibody-independent complement activation in rejection of porcine bone marrow cells in mice. Transplantation. 69: 163-5. PMID 10653396 DOI: 10.1097/00007890-200001150-00027 |
0.428 |
|
| 2000 |
Nikolic B, Zhao G, Swenson K, Sykes M. A novel application of cyclosporine A in nonmyeloablative pretransplant host conditioning for allogeneic BMT Blood. 96: 1166-1172. DOI: 10.1182/Blood.V96.3.1166.015K41_1166_1172 |
0.547 |
|
| 2000 |
Ito H, Kurtz J, Shaffer J, Sykes M. ONE INJECTION OF ANTI-CD40L MAB OVERCOMES CD4 T CELL-MEDIATED RESISTANCE TO FULLY MHC-MISMATCHED ALLOGENEIC MARROW ENGRAFTMENT. Transplantation. 69: S371. DOI: 10.1097/00007890-200004271-00995 |
0.73 |
|
| 2000 |
Wekerle T, Kurtz J, Ito H, Shaffer J, Sykes M. A ONE-DAY PROTOCOL OF BONE MARROW TRANSPLANTATION WITH COSTIMULATORY BLOCKADE FOR THE RAPID INDUCTION OF DONOR-SPECIFIC SKIN GRAFT TOLERANCE WITHOUT PRE-CONDITIONING. Transplantation. 69: S370. DOI: 10.1097/00007890-200004271-00994 |
0.739 |
|
| 2000 |
Kurtz J, Ito H, Shaffer J, Sykes M. SYNERGISTIC EFFECT OF COSTIMULATORY BLOCKADE AND CYCLOSPORIN TREATMENT IN THE ESTABLISHMENT OF EARLY MIXED HEMATAPOIETIC CHIMERISM. Transplantation. 69: S370. DOI: 10.1097/00007890-200004271-00993 |
0.633 |
|
| 2000 |
Alexander SI, Sykes M, McAfee S, Hope J, Preffer F, Sackstein R, Saidman SL, Dombkowski D, Sachs DH, Spitzer TR. CAN MIXED CHIMERISM BE ACHIEVED WITHOUT GVHD ACROSS HLA BARRIERS USING NON-MYELOABLATIVE CONDITIONING WITH EXHAUSTIVE IN VIVO T CELL DEPLETION? PRELIMINARY EXPERIENCE IN PATIENTS WITH HEMATOLOGICAL MALIGNANCIES. Transplantation. 69: S295. DOI: 10.1097/00007890-200004271-00704 |
0.438 |
|
| 2000 |
Rodriguez-Barbosa JI, Zhao Y, Zhao G, Swenson K, Sachs DH, Sykes M. IMPROVED CD4 RECONSTITUTION IN THYMECTOMIZED, T/ NK CELL DEPLETED MICE GRAFTED IN ALTERNATIVE SITES WITH NEONATAL PORCINE THYMUS TISSUE. Transplantation. 69: S257. DOI: 10.1097/00007890-200004271-00561 |
0.489 |
|
| 2000 |
Sykes M. Progress on macrochimerism and tolerance Experimental Hematology. 28: 130-131. DOI: 10.1016/S0301-472X(00)00494-X |
0.591 |
|
| 1999 |
Wekerle T, Sayegh MH, Ito H, Hill J, Cnandraker A, Pearson DA, Swenson KG, Zhao G, Sykes M. Anti-CD154 or CTLA4Ig obviates the need for thymic irradiation in a non- myeloablative conditioning regimen for the induction of mixed hematopoietic chimerism and tolerance Transplantation. 68: 1348-1355. PMID 10573075 DOI: 10.1097/00007890-199911150-00022 |
0.584 |
|
| 1999 |
Sykes M, Pearson DA, Taylor PA, Szot GL, Goldman SJ, Blazar BR. Dose and timing of interleukin (IL)-12 and timing and type of total-body irradiation: Effects on graft-vs.-host disease inhibition and toxicity of exogenous IL-12 in murine bone marrow transplant recipients Biology of Blood and Marrow Transplantation. 5: 277-284. PMID 10534057 DOI: 10.1016/S1083-8791(99)70002-9 |
0.342 |
|
| 1999 |
Spitzer TR, Delmonico F, Tolkoff-Rubin N, McAfee S, Sackstein R, Saidman S, Colby C, Sykes M, Sachs DH, Cosimi AB. Combined histocompatibility leukocyte antigen-matched donor bone marrow and renal transplantation for multiple myeloma with end stage renal disease: The induction of allograft tolerance through mixed lymphohematopoietic chimerism Transplantation. 68: 480-484. PMID 10480403 DOI: 10.1097/00007890-199908270-00006 |
0.385 |
|
| 1999 |
Wekerle T, Sykes M. Mixed chimerism as an approach for the induction of transplantation tolerance. Transplantation. 68: 459-67. PMID 10480398 DOI: 10.1097/00007890-199908270-00001 |
0.463 |
|
| 1999 |
Ohdan H, Yang YG, Shimizu A, Swenson KG, Sykes M. Mixed chimerism induced without lethal conditioning prevents T cell- and anti-Gal alpha 1,3Gal-mediated graft rejection. The Journal of Clinical Investigation. 104: 281-90. PMID 10430609 DOI: 10.1172/Jci6656 |
0.553 |
|
| 1999 |
Dey B, Yang YG, Preffer F, Shimizu A, Swenson K, Dombkowski D, Sykes M. The fate of donor T-cell receptor transgenic T cells with known host antigen specificity in a graft-versus-host disease model. Transplantation. 68: 141-9. PMID 10428282 DOI: 10.1097/00007890-199907150-00026 |
0.521 |
|
| 1999 |
Pelot MR, Pearson DA, Swenson K, Zhao G, Sachs J, Yang YG, Sykes M. Lymphohematopoietic graft-vs.-host reactions can be induced without graft-vs.-host disease in murine mixed chimeras established with a cyclophosphamide-based nonmyeloablative conditioning regimen Biology of Blood and Marrow Transplantation. 5: 133-143. PMID 10392959 DOI: 10.1053/Bbmt.1999.V5.Pm10392959 |
0.588 |
|
| 1999 |
Sykes M, Preffer F, McAfee S, Saidman SL, Weymouth D, Andrews DM, Colby C, Sackstein R, Sachs DH, Spitzer TR. Mixed symphohaemopoietic chimerism and graft-versus-lymphoma effects after non-myeloablative therapy and HLA-mismatched bone-marrow transplantation Lancet. 353: 1755-1759. PMID 10347989 DOI: 10.1016/S0140-6736(98)11135-2 |
0.486 |
|
| 1999 |
Yang YG, Sykes M. The role of interleukin-12 in preserving the graft-versus-leukemia effect of allogeneic CD8 T cells independently of GVHD. Leukemia & Lymphoma. 33: 409-20. PMID 10342569 DOI: 10.3109/10428199909058446 |
0.472 |
|
| 1999 |
Wu A, Esnaola NF, Yamada K, Awwad M, Shimizu A, Huang C, Wain J, Zhao Y, Neville DM, Cooper DKC, Sykes M, Sachs DH. Xenogeneic thymic transplantation in a pig-to-nonhuman primate model. Transplantation Proceedings. 31: 957. PMID 10083424 DOI: 10.1016/S0041-1345(98)01854-5 |
0.45 |
|
| 1999 |
Ohdan H, Yang YG, Sykes M. Reduction of anti-Gal alpha 1-3Gal natural antibodies in sera of alpha 1,3-galactosyltransferase-deficient mice receiving Gal-positive bone marrow transplantation. Transplantation Proceedings. 31: 945-6. PMID 10083418 DOI: 10.1016/S0041-1345(98)01848-X |
0.367 |
|
| 1999 |
Nikolic B, Sykes M. Porcine thymus supports development of human T cells that are tolerant to porcine xenoantigens. Transplantation Proceedings. 31: 924. PMID 10083407 DOI: 10.1016/S0041-1345(98)01838-7 |
0.402 |
|
| 1999 |
Cooke DT, Nikolic B, Sykes M. The role of atypical T cells and NK cells in inhibiting primary engraftment of xenogeneic donor rat bone marrow cells. Transplantation Proceedings. 31: 683. PMID 10083294 DOI: 10.1016/S0041-1345(98)01607-8 |
0.457 |
|
| 1999 |
Wekerle T, Sayegh MH, Chandraker A, Swenson KG, Zhao Y, Sykes M. Role of peripheral clonal deletion in tolerance induction with bone marrow transplantation and costimulatory blockade. Transplantation Proceedings. 31: 680. PMID 10083292 DOI: 10.1016/S0041-1345(98)01605-4 |
0.474 |
|
| 1999 |
Manilay JO, Waneck GL, Sykes M. Altered expression of Ly-49 receptors on NK cells developing in mixed allogeneic bone marrow chimeras. International Immunology. 10: 1943-55. PMID 9885916 DOI: 10.1093/Intimm/10.12.1943 |
0.463 |
|
| 1999 |
Sykes M, Ohdan H, Manilay JO, Wekerle T, Yang YG. Hematopoietic chimerism and tolerance of T cells, B cells, and NK cells. Transplantation Proceedings. 30: 4020. PMID 9865282 DOI: 10.1016/S0041-1345(98)01325-6 |
0.429 |
|
| 1999 |
Wekerle T, Kurtz J, Sykes M. Mixed hematopoietic chimerism and transplantation tolerance: insights from experimental models Current Opinion in Organ Transplantation. 4: 44. DOI: 10.1097/00075200-199903000-00009 |
0.73 |
|
| 1999 |
Wu A, Yamada K, Awwad M, Shimizu A, Watts A, Gojo S, Neville D, Cooper DK, Sykes M, Sachs DH. PROLONGED XENOGENEIC SKIN GRAFT SURVIVAL AFTER XENOGENEIC PORCINE THYMIC TRANSPLANTATION IN A NON-HUMAN PRIMATE MODEL Transplantation. 67: S259. DOI: 10.1097/00007890-199904150-01035 |
0.427 |
|
| 1999 |
Wekerle T, Turka LA, Sayegh MH, Kurtz J, Ito H, Wells AD, Shaffer J, Sykes M. EARLY DELETION AFTER BONE MARROW TRANSPLANTATION WITH COSTIMULATORY BLOCKADE IS FAS-DEPENDENT AND IS PREVENTED BY BCL-XL OVEREXPRESSION Transplantation. 67: S242. DOI: 10.1097/00007890-199904150-00965 |
0.721 |
|
| 1999 |
Kurtz J, Wekerle T, Ito H, Shaffer J, Sykes M. AN UNEXPECTED ROLE FOR CD28 AND LACK OF A ROLE FOR CD40L SIGNALING IN PERIPHERAL DELETION OF DONOR-REACTIVE CD4+ T CELLS AND ESTABLISHMENT OF MIXED CHIMERISM THROUGH COSTIMULATORY BLOCKADE Transplantation. 67: S120. DOI: 10.1097/00007890-199904150-00481 |
0.717 |
|
| 1999 |
Haller GW, Esnaola N, Yamada K, Wu A, Shimizu A, Colvin RB, Sykes M, Sachs DH. INDUCTION OF T CELL TOLERANCE IN MINIATURE SWINE WITH ALLOGENEIC THYMUS TRANSPLANTS ACROSS A CLASS I BARRIER Transplantation. 67: S68. DOI: 10.1097/00007890-199904150-00275 |
0.547 |
|
| 1999 |
Wekerle T, Sayegh MH, Kurtz J, Ronquillo JV, Dong V, Swenson KG, Zhao G, Sykes M. SUBSTANTIAL DONOR CHIMERISM AND TOLERANCE ACROSS A FULL MHC BARRIER WITHOUT HOST PRE-CONDITIONING Transplantation. 67: S34. DOI: 10.1097/00007890-199904150-00138 |
0.672 |
|
| 1999 |
Ito H, Wekerle T, Kurtz J, Sayegh MH, Hill J, Chandraker A, Pearson DA, Swenson KG, Zhao G, Sykes M. INDUCTION OF MIXED HEMATOPOIETIC CHIMERISM AND TOLERANCE WITH SUBOPTIMAL RECIPIENT T CELL DEPLETION, 3GY TBI AND ANTI-CD154 OR CTLA4Ig: TOWARD A CLINICAL REGIMEN USEFUL FOR CADAVERIC DONORS Transplantation. 67: S34. DOI: 10.1097/00007890-199904150-00137 |
0.766 |
|
| 1999 |
Sykes M. Transplantation: Bone marrow and solid organ transplantation start to converge Current Opinion in Immunology. 11: 493-496. DOI: 10.1016/S0952-7915(99)00018-7 |
0.472 |
|
| 1998 |
Yang YG, Dey BR, Sergio JJ, Pearson DA, Sykes M. Donor-derived interferon γ is required for inhibition of acute graft- versus-host disease by interleukin 12 Journal of Clinical Investigation. 102: 2126-2135. PMID 9854048 DOI: 10.1172/Jci4992 |
0.393 |
|
| 1998 |
Manilay JO, Sykes M. Natural killer cells and their role in graft rejection. Current Opinion in Immunology. 10: 532-8. PMID 9794835 DOI: 10.1016/S0952-7915(98)80219-7 |
0.522 |
|
| 1998 |
Dey B, Sykes M, Spitzer TR. Outcomes of recipients of both bone marrow and solid organ transplants: A review Medicine. 77: 355-369. PMID 9772924 DOI: 10.1097/00005792-199809000-00005 |
0.497 |
|
| 1998 |
Wekerle T, Sachs DH, Sykes M. Mixed chimerism for the induction of tolerance: potential applicability in clinical composite tissue grafting. Transplantation Proceedings. 30: 2708-10. PMID 9745551 DOI: 10.1016/S0041-1345(98)00793-3 |
0.333 |
|
| 1998 |
Simon AR, Warrens AN, Yazzie NP, Seebach JD, Sachs DH, Sykes M. Cross-species interaction of porcine and human integrins with their respective ligands: implications for xenogeneic tolerance induction. Transplantation. 66: 385-94. PMID 9721809 DOI: 10.1097/00007890-199808150-00017 |
0.437 |
|
| 1998 |
Warrens AN, Simon AR, Theodore PR, Sachs DH, Sykes M. Function of porcine adhesion molecules in a human marrow microenvironment. Transplantation. 66: 252-9. PMID 9701274 DOI: 10.1097/00007890-199807270-00020 |
0.487 |
|
| 1998 |
Manilay JO, Pearson DA, Sergio JJ, Swenson KG, Sykes M. Intrathymic deletion of alloreactive T cells in mixed bone marrow chimeras prepared with a nonmyeloablative conditioning regimen Transplantation. 66: 96-102. PMID 9679828 DOI: 10.1097/00007890-199807150-00015 |
0.627 |
|
| 1998 |
Yang YG, deGoma E, Barth R, Sergio JJ, Sykes M. B-cell reconstitution and xenoreactive anti-pig natural antibody production in severe combined immunodeficient mice reconstituted with immunocompetent B cells from varying sources. Transplantation. 66: 89-95. PMID 9679827 DOI: 10.1097/00007890-199807150-00014 |
0.343 |
|
| 1998 |
Wekerle T, Sayegh MH, Hill J, Zhao Y, Chandraker A, Swenson KG, Zhao G, Sykes M. Extrathymic T cell deletion and allogeneic stem cell engraftment induced with costimulatory blockade is followed by central T cell tolerance. The Journal of Experimental Medicine. 187: 2037-44. PMID 9625763 DOI: 10.1084/Jem.187.12.2037 |
0.632 |
|
| 1998 |
Nikolic B, Lei H, Pearson DA, Sergio JJ, Swenson KG, Sykes M. Role of intrathymic rat class II+ cells in maintaining deletional tolerance in xenogeneic rat→mouse bone marrow chimeras Transplantation. 65: 1216-1224. PMID 9603171 DOI: 10.1097/00007890-199805150-00013 |
0.468 |
|
| 1998 |
Yang YG, deGoma E, Ohdan H, Bracy JL, Xu Y, Iacomini J, Thall AD, Sykes M. Tolerization of anti-Galalpha1-3Gal natural antibody-forming B cells by induction of mixed chimerism. The Journal of Experimental Medicine. 187: 1335-42. PMID 9547344 DOI: 10.1084/Jem.187.8.1335 |
0.494 |
|
| 1998 |
Zhao Y, Barth RN, Swenson K, Pearson DA, Sykes M. Functionally and phenotypically mature mouse CD8+ T cells develop in porcine thymus grafts in mice Xenotransplantation. 5: 99-104. PMID 9507740 DOI: 10.1111/J.1399-3089.1998.Tb00015.X |
0.542 |
|
| 1998 |
Nikolic B, Sykes M. Bone marrow chimerism and transplantation tolerance. Current Opinion in Immunology. 9: 634-40. PMID 9368771 DOI: 10.1016/S0952-7915(97)80042-8 |
0.563 |
|
| 1998 |
Dey BR, Yang Y, Szot GL, Pearson DA, Sykes M. Interleukin-12 Inhibits Graft-Versus-Host Disease Through an Fas-Mediated Mechanism Associated With Alterations in Donor T-Cell Activation and Expansion Blood. 91: 3315-3322. DOI: 10.1182/Blood.V91.9.3315.3315_3315_3322 |
0.521 |
|
| 1998 |
Wu A, Esnaola NF, Yamada K, Awwad M, Shimizu A, Huang C, Wain J, Zhao Y, Neville D, Cooper DK, Sykes M, Sachs DH. XENOGENEIC THYMIC TRANSPLANTATION IN A PIG-TO-NON-HUMAN-PRIMATE MODEL Transplantation. 65: 194. DOI: 10.1097/00007890-199805131-00462 |
0.424 |
|
| 1998 |
Wekerle T, Sayegh MH, Hill J, Chandraker A, Swenson KA, Zhao G, Sykes M. HIGH LEVELS OF STABLE MULTI-LINEAGE HEMATOPOIETIC CHIMERISM AND DONOR-SPECIFIC ALLOGENEIC SKIN GRAFT TOLERANCE WITH T-CELL COSTIMULATORY BLOCKADE Transplantation. 65: 157. DOI: 10.1097/00007890-199805131-00313 |
0.51 |
|
| 1998 |
Zhao Y, Swenson K, Zhao G, Sykes M. ROLE OF REGULATORY CELLS DEVELOPING IN PORCINE THYMUS GRAFTS IN TOLERANCE TO BOTH HOST AND DONOR ANTIGENS Transplantation. 65: 88. DOI: 10.1097/00007890-199805131-00039 |
0.392 |
|
| 1997 |
Nikolic B, Sykes M. Mixed hematopoietic chimerism and transplantation tolerance. Immunologic Research. 16: 217-28. PMID 9379073 DOI: 10.1007/Bf02786391 |
0.552 |
|
| 1997 |
Yang YG, Dey B, Sergio JJ, Sykes M. Interleukin-12 prevents severe acute graft-versus-host disease (GVHD) and GVHD-associated immune dysfunction in a fully major histocompatibility complex haplotype-mismatched murine bone marrow transplantation model Transplantation. 64: 1343-1352. PMID 9371678 DOI: 10.1097/00007890-199711150-00018 |
0.532 |
|
| 1997 |
Sykes M, Zhao Y, Yang YG. Tolerance induction for xenotransplantation. World Journal of Surgery. 21: 932-8. PMID 9361507 DOI: 10.1007/S002689900329 |
0.508 |
|
| 1997 |
Zhao Y, Sykes M. Resistance to monoclonal antibody-induced CD8+ T-cell depletion in thymectomized MHC class II-deficient mice. Transplantation. 64: 489-94. PMID 9275117 DOI: 10.1097/00007890-199708150-00019 |
0.436 |
|
| 1997 |
Sykes M, Szot GL, Swenson KA, Pearson DA. Induction of high levels of allogeneic hematopoietic reconstitution and donor-specific tolerance without myelosuppressive conditioning Nature Medicine. 3: 783-787. PMID 9212108 DOI: 10.1038/Nm0797-783 |
0.601 |
|
| 1997 |
Mayfield RS, Hayashi H, Sawada T, Bergen K, LeGuern C, Sykes M, Sachs DH, Iacomini J. The mechanism of specific prolongation of class I-mismatched skin grafts induced by retroviral gene therapy. European Journal of Immunology. 27: 1177-81. PMID 9174608 DOI: 10.1002/Eji.1830270519 |
0.445 |
|
| 1997 |
Zhao Y, Sergio JJ, Pearson DA, Szot GL, Arn JS, Sachs DH, Sykes M. Repopulation of mouse CD4 cells in BALB/c nude mice receiving fetal pig thymus/liver grafts Transplantation Proceedings. 29: 1228-1229. PMID 9123286 DOI: 10.1016/S0041-1345(96)00569-6 |
0.348 |
|
| 1997 |
Hayashi H, Mayfield RS, Sawada T, Germana S, Sykes M, Iacomini J, Sachs DH, LeGuern C. Role of the thymus in donor specific hyporesponsiveness induced by retroviral transduction of bone marrow using an MHC class I gene. Transplantation Proceedings. 29: 1133. PMID 9123234 DOI: 10.1016/S0041-1345(96)00467-8 |
0.379 |
|
| 1997 |
Khan A, Sergio JJ, Zhao Y, Pearson DA, Sachs DH, Sykes M. Discordant xenogeneic neonatal thymic transplantation can induce donor- specific tolerance Transplantation. 63: 124-131. PMID 9000673 DOI: 10.1097/00007890-199701150-00023 |
0.539 |
|
| 1997 |
Sykes M. Chimerism and central tolerance. Current Opinion in Immunology. 8: 694-703. PMID 8902396 DOI: 10.1016/S0952-7915(96)80088-4 |
0.43 |
|
| 1997 |
Yang Y, Sergio JJ, Pearson DA, Szot GL, Shimizu A, Sykes M. Interleukin-12 Preserves the Graft-Versus-Leukemia Effect of Allogeneic CD8 T Cells While Inhibiting CD4-Dependent Graft-Versus-Host Disease in Mice Blood. 90: 4651-4660. DOI: 10.1182/Blood.V90.11.4651.4651_4651_4660 |
0.525 |
|
| 1997 |
Yang Y, Sergio JJ, Sykes M. Engraftment of discordant xenogeneic swine bone marrow cells in immunodeficient mice Xenotransplantation. 4: 235-244. DOI: 10.1111/J.1399-3089.1997.Tb00188.X |
0.499 |
|
| 1996 |
Zhao Y, Swenson K, Sergio JJ, Arn JS, Sachs DH, Sykes M. Skin graft tolerance across a discordant xenogeneic barrier. Nature Medicine. 2: 1211-6. PMID 8898747 DOI: 10.1038/Nm1196-1211 |
0.512 |
|
| 1996 |
Khan A, Tomita Y, Sykes M. Thymic dependence of loss of tolerance in mixed allogeneic bone marrow chimeras after depletion of donor antigen. Peripheral mechanisms do not contribute to maintenance of tolerance. Transplantation. 62: 380-7. PMID 8779687 DOI: 10.1097/00007890-199608150-00014 |
0.559 |
|
| 1996 |
Hayashi H, LeGuern C, Sachs DH, Sykes M. Long-term engraftment of precultured post-5-fluorouracil allogeneic marrow in mice conditioned with a nonmyeloablative regimen: relevance for a gene therapy approach to tolerance induction. Transplant Immunology. 4: 86-90. PMID 8762020 DOI: 10.1016/S0966-3274(96)80044-X |
0.52 |
|
| 1996 |
Sykes M. Immunobiology of transplantation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 10: 721-30. PMID 8635689 DOI: 10.1096/fasebj.10.7.8635689 |
0.36 |
|
| 1996 |
Tomita Y, Khan A, Sykes M. Mechanism by which additional monoclonal antibody (mAB) injections overcome the requirement for thymic irradiation to achieve mixed chimerism in mice receiving bone marrow transplantation after conditioning with anti-T cell mABs and 3-Gy whole body irradiation. Transplantation. 61: 477-85. PMID 8610364 DOI: 10.1097/00007890-199602150-00028 |
0.583 |
|
| 1996 |
Tomita Y, Sachs DH, Khan A, Sykes M. Additional monoclonal antibody (mAB) injections can replace thymic irradiation to allow induction of mixed chimerism and tolerance in mice receiving bone marrow transplantation after conditioning with anti-T cell mABs and 3-Gy whole body irradiation. Transplantation. 61: 469-77. PMID 8610363 DOI: 10.1097/00007890-199602150-00027 |
0.568 |
|
| 1996 |
Lee LA, Sergio JJ, Sykes M. Natural killer cells weakly resist engraftment of allogeneic, long-term, multilineage-repopulating hematopoietic stem cells Transplantation. 61: 125-132. PMID 8560550 DOI: 10.1097/00007890-199601150-00024 |
0.518 |
|
| 1996 |
Gritsch HA, Sykes M. Host marrow has a competitive advantage that limits donor hematopoietic repopulation in mixed xenogeneic chimeras Xenotransplantation. 3: 312-320. DOI: 10.1111/J.1399-3089.1996.Tb00153.X |
0.471 |
|
| 1996 |
Yang Y, Sergio JJ, Swenson K, Glaser RM, Monroy R, Sykes M. Donor-specific growth factors promote swine hematopoiesis in severe combined immune deficient mice Xenotransplantation. 3: 92-101. DOI: 10.1111/J.1399-3089.1996.Tb00125.X |
0.526 |
|
| 1995 |
Wang MG, Szebeni J, Pearson DA, Szot GL, Sykes M. Inhibition of graft-versus-host disease by interleukin-2 treatment is associated with altered cytokine production by expanded graft-versus-ho st-reactive CD4<sup>+</sup> helper cells Transplantation. 60: 481-490. PMID 7676498 DOI: 10.1097/00007890-199509000-00014 |
0.424 |
|
| 1995 |
Sykes M, Szot GL, Nguyen PL, Pearson DA. Interleukin-12 inhibits murine graft-versus-host disease Blood. 86: 2429-2438. DOI: 10.1182/Blood.V86.6.2429.Bloodjournal8662429 |
0.513 |
|
| 1995 |
Sablinski T, Latinne D, Gianello P, Bailin M, Bergen K, Colvin RB, Foley A, Hong H, Lorf T, Meehan S, Monroy R, Powelson JA, Sykes M, Tanak M, Cosimi AB, et al. Xenotransplantation of pig kidneys to nonhuman primates:I. Development of the model Xenotransplantation. 2: 264-270. DOI: 10.1111/J.1399-3089.1995.Tb00107.X |
0.429 |
|
| 1995 |
Lee LA, Sergio JJ, Sykes M. Evidence for nonimmune mechanisms in the loss of hematopoietic chimerism in rat→mouse mixed xenogeneic chimeras Xenotransplantation. 2: 57-66. DOI: 10.1111/J.1399-3089.1995.Tb00068.X |
0.497 |
|
| 1994 |
Sykes M, Harty MW, Pearson DA. Strain dependence of interleukin-2-induced graft-versus-host disease protection: Evidence that interleukin-2 inhibits selected CD4 functions Journal of Immunotherapy. 15: 11-21. PMID 8110726 DOI: 10.1097/00002371-199401000-00002 |
0.478 |
|
| 1994 |
Lee LA, Gritsch HA, Sergio JJ, Arn JS, Glaser RM, Sablinski T, Sachs DH, Sykes M. Specific tolerance across a discordant xenogeneic transplantation barrier. Proceedings of the National Academy of Sciences of the United States of America. 91: 10864-7. PMID 7971974 DOI: 10.1073/Pnas.91.23.10864 |
0.613 |
|
| 1994 |
Gritsch HA, Glaser RM, Emery DW, Lee LA, Smith CV, Sablinski T, Arn JS, Sachs DH, Sykes M. The importance of nonimmune factors in reconstitution by discordant xenogeneic hematopoietic cells Transplantation. 57: 906-917. PMID 7908768 DOI: 10.1097/00007890-199403270-00024 |
0.418 |
|
| 1994 |
Sykes M, Harty MW, Szot GL, Pearson DA. Interleukin-2 inhibits graft-versus-host disease-promoting activity of CD4+ cells while preserving CD4- and CD8-mediated graft-versus-leukemia effects Blood. 83: 2560-2569. DOI: 10.1182/Blood.V83.9.2560.2560 |
0.546 |
|
| 1994 |
Tomita Y, Sachs D, Sykes M. Myelosuppressive conditioning is required to achieve engraftment of pluripotent stem cells contained in moderate doses of syngeneic bone marrow Blood. 83: 939-948. DOI: 10.1182/Blood.V83.4.939.Bloodjournal834939 |
0.516 |
|
| 1994 |
Tomita Y, Lee LA, Sykes M. Engraftment of rat bone marrow and its role in negative selection of murine T cells in mice conditioned with a modified nonmyeloablative regimen Xenotransplantation. 1: 109-117. DOI: 10.1111/J.1399-3089.1994.Tb00056.X |
0.509 |
|
| 1994 |
Latinne D, Vitiello DM, Sachs DH, Sykes M. Tolerance to discordant xenografts. I. Sharing of human natural antibody determinants on miniature swine bone marrow cells and endothelial cells. Transplantation. 57: 238-244. DOI: 10.1097/00007890-199401001-00015 |
0.471 |
|
| 1993 |
Sykes M, Sachs DH, Nienhuis AW, Pearson DA, Moulton AD, Bodine DM. Specific prolongation of skin graft survival following retroviral transduction of bone marrow with an allogeneic major histocompatibility complex gene. Transplantation. 55: 197-202. PMID 8420048 DOI: 10.1097/00007890-199301000-00037 |
0.507 |
|
| 1993 |
Sykes M, Harty MW, Karlhofer FM, Pearson DA, Szot G, Yokoyama W. Hematopoietic cells and radioresistant host elements influence natural killer cell differentiation Journal of Experimental Medicine. 178: 223-229. PMID 8315379 DOI: 10.1084/Jem.178.1.223 |
0.419 |
|
| 1993 |
Sykes M. Novel Approaches To The Control Of Graft Versus Host Disease Current Opinion in Immunology. 5: 774-781. PMID 8240740 DOI: 10.1016/0952-7915(93)90136-G |
0.452 |
|
| 1992 |
Aksentijevich I, Sachs DH, Sykes M. Humoral tolerance in xenogeneic BMT recipients conditioned by a nonmyeloablative regimen. Transplantation. 53: 1108-14. PMID 1585475 DOI: 10.1097/00007890-199205000-00025 |
0.526 |
|
| 1992 |
Sykes M, Abraham VS. The mechanism of IL-2-mediated protection against GVHD in mice. II. Protection occurs independently of NK/LAK cells. Transplantation. 53: 1063-70. PMID 1533968 DOI: 10.1097/00007890-199205000-00018 |
0.31 |
|
| 1990 |
Sykes M, Romick ML, Sachs DH. Interleukin 2 prevents graft-versus-host disease while preserving the graft-versus-leukemia effect of allogeneic T cells. Proceedings of the National Academy of Sciences of the United States of America. 87: 5633-7. PMID 2377601 DOI: 10.1073/pnas.87.15.5633 |
0.441 |
|
| 1990 |
Sykes M, Romick ML, Hoyles KA, Sachs DH. In vivo administration of interleukin 2 plus T cell-depleted syngeneic marrow prevents graft-versus-host disease mortality and permits alloengraftment. The Journal of Experimental Medicine. 171: 645-58. PMID 2307931 DOI: 10.1084/jem.171.3.645 |
0.33 |
|
| 1990 |
Sykes M, Hoyles KA, Romick ML, Sachs DH. In vitro and in vivo analysis of bone marrow-derived CD3+, CD4-, CD8-, NK1.1+ cell lines. Cellular Immunology. 129: 478-93. PMID 2143439 DOI: 10.1016/0008-8749(90)90222-D |
0.437 |
|
| 1990 |
Sykes M, Sharabi Y, Sachs DH. Natural suppressor cells in spleens of irradiated, bone marrow-reconstituted mice and normal bone marrow: lack of Sca-1 expression and enrichment by depletion of Mac1-positive cells. Cellular Immunology. 127: 260-74. PMID 1970279 DOI: 10.1016/0008-8749(90)90131-A |
0.409 |
|
| 1989 |
Sykes M, Sheard MA, Sachs DH. Graft-versus-host-related immunosuppression is induced in mixed chimeras by alloresponses against either host or donor lymphohematopoietic cells. The Journal of Experimental Medicine. 168: 2391-6. PMID 3264329 DOI: 10.1084/jem.168.6.2391 |
0.365 |
|
| 1989 |
Sykes M, Sachs DH. Mixed allogeneic chimerism as an approach to transplantation tolerance. Immunology Today. 9: 23-7. PMID 3076756 DOI: 10.1016/0167-5699(88)91352-7 |
0.365 |
|
| 1989 |
Chester CH, Sykes M, Sachs DH. Multiple mixed chimeras: reconstitution of lethally irradiated mice with syngeneic plus allogeneic bone marrow from multiple strains. Research in Immunology. 140: 503-16. PMID 2675227 DOI: 10.1016/0923-2494(89)90116-8 |
0.413 |
|
| 1989 |
Rüedi E, Sykes M, Ildstad ST, Chester CH, Althage A, Hengartner H, Sachs DH, Zinkernagel RM. Antiviral T cell competence and restriction specificity of mixed allogeneic (P1 + P2----P1) irradiation chimeras. Cellular Immunology. 121: 185-95. PMID 2470518 DOI: 10.1016/0008-8749(89)90016-6 |
0.342 |
|
| 1988 |
Sykes M, Sheard MA, Sachs DH. Effects of T cell depletion in radiation bone marrow chimeras. II. Requirement for allogeneic T cells in the reconstituting bone marrow inoculum for subsequent resistance to breaking of tolerance. The Journal of Experimental Medicine. 168: 661-73. PMID 3045249 DOI: 10.1084/jem.168.2.661 |
0.464 |
|
| 1988 |
Sykes M, Sachs DH. Mechanisms of suppression in mixed allogeneic chimeras. Transplantation. 46: 135S-142S. PMID 2970138 DOI: 10.1097/00007890-198808001-00025 |
0.459 |
|
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