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Aditi U. Gurkar, Ph.D. - Publications

Affiliations: 
2010 Boston University, Boston, MA, United States 
Area:
Molecular Biology, Cell Biology
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14 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Han S, Sims A, Aceto A, Schmidt BF, Bruchez MP, Gurkar AU. A Chemoptogenetic Tool for Spatiotemporal Induction of Oxidative DNA Lesions . Genes. 14. PMID 36833412 DOI: 10.3390/genes14020485  0.459
2022 Hamsanathan S, Anthonymuthu T, Han S, Shinglot H, Siefken E, Sims A, Sen P, Pepper HL, Snyder NW, Bayir H, Kagan V, Gurkar AU. Integrated -omics approach reveals persistent DNA damage rewires lipid metabolism and histone hyperacetylation via MYS-1/Tip60. Science Advances. 8: eabl6083. PMID 35171671 DOI: 10.1126/sciadv.abl6083  0.413
2021 Marchal L, Hamsanathan S, Karthikappallil R, Han S, Shinglot H, Gurkar AU. Analysis of representative mutants for key DNA repair pathways on healthspan in Caenorhabditis elegans. Mechanisms of Ageing and Development. 111573. PMID 34562508 DOI: 10.1016/j.mad.2021.111573  0.461
2020 Zhao J, Zhang L, Lu A, Han Y, Colangelo D, Bukata C, Scibetta A, Yousefzadeh MJ, Li X, Gurkar AU, McGowan SJ, Angelini L, O'Kelly R, Li H, Corbo L, et al. ATM is a key driver of NF-κB-dependent DNA-damage-induced senescence, stem cell dysfunction and aging. Aging. 12. PMID 32201398 DOI: 10.18632/aging.102863  0.403
2018 Gurkar AU, Robinson AR, Cui Y, Li X, Allani SK, Webster A, Muravia M, Fallahi M, Weissbach H, Robbins PD, Wang Y, Kelley EE, Croix CMS, Niedernhofer LJ, Gill MS. Dysregulation of DAF-16/FOXO3A-mediated stress responses accelerates oxidative DNA damage induced aging. Redox Biology. 18: 191-199. PMID 30031267 DOI: 10.1016/J.Redox.2018.06.005  0.486
2018 Niedernhofer LJ, Gurkar AU, Wang Y, Vijg J, Hoeijmakers JHJ, Robbins PD. Nuclear Genomic Instability and Aging. Annual Review of Biochemistry. 87: 295-322. PMID 29925262 DOI: 10.1146/Annurev-Biochem-062917-012239  0.395
2018 Czerwińska J, Nowak M, Wojtczak P, Dziuban-Lech D, Cieśla JM, Kołata D, Gajewska B, Barańczyk-Kuźma A, Robinson AR, Shane HL, Gregg SQ, Rigatti LH, Yousefzadeh MJ, Gurkar AU, McGowan SJ, et al. ERCC1-deficient cells and mice are hypersensitive to lipid peroxidation. Free Radical Biology & Medicine. PMID 29860127 DOI: 10.1016/J.Freeradbiomed.2018.05.088  0.572
2018 Robinson AR, Yousefzadeh MJ, Rozgaja TA, Wang J, Li X, Tilstra JS, Feldman CH, Gregg SQ, Johnson CH, Skoda EM, Frantz MC, Bell-Temin H, Pope-Varsalona H, Gurkar AU, Nasto LA, et al. Spontaneous DNA damage to the nuclear genome promotes senescence, redox imbalance and aging. Redox Biology. 17: 259-273. PMID 29747066 DOI: 10.1016/J.Redox.2018.04.007  0.454
2017 Zhao J, Fuhrmann-Stroissnigg H, Gurkar AU, Flores RR, Dorronsoro A, Stolz DB, St Croix CM, Niedernhofer LJ, Robbins PD. Quantitative Analysis of Cellular Senescence in Culture and In Vivo. Current Protocols in Cytometry. 79: 9.51.1-9.51.25. PMID 28055114 DOI: 10.1002/Cpcy.16  0.422
2015 Zhu Y, Tchkonia T, Pirtskhalava T, Gower AC, Ding H, Giorgadze N, Palmer AK, Ikeno Y, Hubbard GB, Lenburg M, O'Hara SP, LaRusso NF, Miller JD, Roos CM, Verzosa GC, ... ... Gurkar AU, et al. The Achilles' heel of senescent cells: from transcriptome to senolytic drugs. Aging Cell. 14: 644-58. PMID 25754370 DOI: 10.1111/Acel.12344  0.326
2013 Gurkar AU, Chu K, Raj L, Bouley R, Lee SH, Kim YB, Dunn SE, Mandinova A, Lee SW. Identification of ROCK1 kinase as a critical regulator of Beclin1-mediated autophagy during metabolic stress. Nature Communications. 4: 2189. PMID 23877263 DOI: 10.1038/Ncomms3189  0.415
2012 Barkley LR, Palle K, Durando M, Day TA, Gurkar A, Kakusho N, Li J, Masai H, Vaziri C. c-Jun N-terminal kinase-mediated Rad18 phosphorylation facilitates Polη recruitment to stalled replication forks. Molecular Biology of the Cell. 23: 1943-54. PMID 22456510 DOI: 10.1091/Mbc.E11-10-0829  0.555
2011 Raj L, Ide T, Gurkar AU, Foley M, Schenone M, Li X, Tolliday NJ, Golub TR, Carr SA, Shamji AF, Stern AM, Mandinova A, Schreiber SL, Lee SW. Selective killing of cancer cells by a small molecule targeting the stress response to ROS. Nature. 475: 231-4. PMID 21753854 DOI: 10.1038/Nature10167  0.364
2010 Song IY, Palle K, Gurkar A, Tateishi S, Kupfer GM, Vaziri C. Rad18-mediated translesion synthesis of bulky DNA adducts is coupled to activation of the Fanconi anemia DNA repair pathway. The Journal of Biological Chemistry. 285: 31525-36. PMID 20675655 DOI: 10.1074/Jbc.M110.138206  0.57
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