Katalin Szaszi - Publications

Affiliations: 
Medical Science University of Toronto, Toronto, ON, Canada 
Area:
Molecular Biology, Cell Biology

67 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Anwer S, Branchard E, Dan Q, Dan A, Szaszi K. Tumor Necrosis Factor-α Induces Claudin-3 Upregulation in Kidney Tubular Epithelial Cells through NFκB and CREB1. American Journal of Physiology. Cell Physiology. PMID 33439776 DOI: 10.1152/ajpcell.00185.2020  0.467
2019 Venugopal S, Anwer S, Szászi K. Claudin-2: Roles beyond Permeability Functions. International Journal of Molecular Sciences. 20. PMID 31726679 DOI: 10.3390/Ijms20225655  0.369
2019 Dan Q, Shi Y, Rabani R, Venugopal S, Xiao J, Anwer S, Ding M, Speight P, Pan W, Alexander RT, Kapus A, Szászi K. Claudin-2 suppresses GEF-H1, RHOA, and MRTF thereby impacting proliferation and profibrotic phenotype of tubular cells. The Journal of Biological Chemistry. PMID 31481470 DOI: 10.1074/Jbc.Ra118.006484  0.545
2019 Bialik JF, Ding M, Speight P, Dan Q, Miranda MZ, Di Ciano-Oliveira C, Kofler MM, Rotstein OD, Pedersen SF, Szászi K, Kapus A. Profibrotic epithelial phenotype: a central role for MRTF and TAZ. Scientific Reports. 9: 4323. PMID 30867502 DOI: 10.1038/S41598-019-40764-7  0.448
2018 Kofler M, Speight P, Little D, Di Ciano-Oliveira C, Szászi K, Kapus A. Mediated nuclear import and export of TAZ and the underlying molecular requirements. Nature Communications. 9: 4966. PMID 30470756 DOI: 10.1038/S41467-018-07450-0  0.407
2018 Rabani R, Volchuk A, Jerkic M, Ormesher L, Garces-Ramirez L, Canton J, Masterson C, Gagnon S, Tatham KC, Marshall J, Grinstein S, Laffey JG, Szaszi K, Curley GF. Mesenchymal stem cells enhance NOX2 dependent ROS production and bacterial killing in macrophages during sepsis. The European Respiratory Journal. PMID 29519920 DOI: 10.1183/13993003.02021-2017  0.323
2017 Amoozadeh Y, Anwer S, Dan Q, Venugopal S, Shi Y, Branchard E, Liedtke E, Ailenberg M, Rotstein OD, Kapus A, Szaszi K. Cell confluence regulates claudin-2 expression: possible role for ZO-1 and Rac. American Journal of Physiology. Cell Physiology. ajpcell.00234.2017. PMID 29187366 DOI: 10.1152/Ajpcell.00234.2017  0.465
2017 Miranda MZ, Bialik JF, Speight P, Dan Q, Yeung T, Szászi K, Pedersen SF, Kapus A. TGF-β1 regulates the expression and transcriptional activity of TAZ via a Smad3-independent, myocardin-related transcription factor-mediated mechanism. The Journal of Biological Chemistry. PMID 28739802 DOI: 10.1074/Jbc.M117.780502  0.495
2016 Amoozadeh Y, Dan Q, Anwer S, Huang HH, Barbieri V, Waheed F, Maishan M, Szászi K. Tumor Necrosis Factor-α Increases Claudin-1, 4 and 7 Expression in Tubular Cells: Role in Permeability Changes. Journal of Cellular Physiology. PMID 27966776 DOI: 10.1002/Jcp.25736  0.755
2016 Speight P, Kofler M, Szászi K, Kapus A. Context-dependent switch in chemo/mechanotransduction via multilevel crosstalk among cytoskeleton-regulated MRTF and TAZ and TGFβ-regulated Smad3. Nature Communications. 7: 11642. PMID 27189435 DOI: 10.1038/Ncomms11642  0.438
2016 Tsang JL, Jia SH, Parodo J, Plant P, Lodyga M, Charbonney E, Szaszi K, Kapus A, Marshall JC. Tyrosine Phosphorylation of Caspase-8 Abrogates Its Apoptotic Activity and Promotes Activation of c-Src. Plos One. 11: e0153946. PMID 27101103 DOI: 10.1371/Journal.Pone.0153946  0.41
2016 Rozycki M, Bialik JF, Speight P, Dan Q, Knudsen TE, Szeto SG, Yuen DA, Szászi K, Pedersen SF, Kapus A. Myocardin-related Transcription Factor Regulates Nox4 Protein Expression: LINKING CYTOSKELETAL ORGANIZATION TO REDOX STATE. The Journal of Biological Chemistry. 291: 227-43. PMID 26555261 DOI: 10.1074/Jbc.M115.674606  0.446
2015 Yin J, Michalick L, Tang C, Tabuchi A, Goldenberg N, Dan Q, Awwad K, Wang L, Erfinanda L, Nouailles-Kursar G, Witzenrath M, Vogelzang A, Lv L, Lee WL, Zhang H, ... ... Szaszi K, et al. Role of Transient Receptor Potential Vanilloid 4 in Neutrophil Activation and Acute Lung Injury. American Journal of Respiratory Cell and Molecular Biology. PMID 26222277 DOI: 10.1165/Rcmb.2014-0225Oc  0.372
2015 Amoozadeh Y, Dan Q, Xiao J, Waheed F, Szászi K. Tumor necrosis factor-α induces a biphasic change in claudin-2 expression in tubular epithelial cells: role in barrier functions. American Journal of Physiology. Cell Physiology. 309: C38-50. PMID 25948735 DOI: 10.1152/Ajpcell.00388.2014  0.75
2015 Tawadros PS, Powers KA, Ailenberg M, Birch SE, Marshall JC, Szaszi K, Kapus A, Rotstein OD. Oxidative Stress Increases Surface Toll-Like Receptor 4 Expression in Murine Macrophages via Ceramide Generation. Shock (Augusta, Ga.). PMID 25944793 DOI: 10.1097/Shk.0000000000000392  0.407
2015 Ailenberg M, Di Ciano-Oliveira C, Szaszi K, Dan Q, Rozycki M, Kapus A, Rotstein OD. Dynasore enhances the formation of mitochondrial antiviral signalling aggregates and endocytosis-independent NF-κB activation. British Journal of Pharmacology. 172: 3748-63. PMID 25850711 DOI: 10.1111/Bph.13162  0.423
2014 Szaszi K, Amoozadeh Y. New insights into functions, regulation, and pathological roles of tight junctions in kidney tubular epithelium. International Review of Cell and Molecular Biology. 308: 205-71. PMID 24411173 DOI: 10.1016/B978-0-12-800097-7.00006-3  0.331
2014 Mouawad F, Aoudjit L, Jiang R, Szaszi K, Takano T. Role of guanine nucleotide exchange factor-H1 in complement-mediated RhoA activation in glomerular epithelial cells. The Journal of Biological Chemistry. 289: 4206-18. PMID 24356971 DOI: 10.1074/Jbc.M113.506816  0.517
2013 Waheed F, Dan Q, Amoozadeh Y, Zhang Y, Tanimura S, Speight P, Kapus A, Szászi K. Central role of the exchange factor GEF-H1 in TNF-α-induced sequential activation of Rac, ADAM17/TACE, and RhoA in tubular epithelial cells. Molecular Biology of the Cell. 24: 1068-82. PMID 23389627 DOI: 10.1091/Mbc.E12-09-0661  0.775
2013 Ly DL, Waheed F, Lodyga M, Speight P, Masszi A, Nakano H, Hersom M, Pedersen SF, Szászi K, Kapus A. Hyperosmotic stress regulates the distribution and stability of myocardin-related transcription factor, a key modulator of the cytoskeleton. American Journal of Physiology. Cell Physiology. 304: C115-27. PMID 23054059 DOI: 10.1152/Ajpcell.00290.2012  0.76
2012 Waheed F, Speight P, Dan Q, Garcia-Mata R, Szaszi K. Affinity precipitation of active Rho-GEFs using a GST-tagged mutant Rho protein (GST-RhoA(G17A)) from epithelial cell lysates. Journal of Visualized Experiments : Jove. PMID 22491204 DOI: 10.3791/3932  0.734
2012 Martin-Martin N, Dan Q, Amoozadeh Y, Waheed F, McMorrow T, Ryan MP, Szászi K. RhoA and Rho kinase mediate cyclosporine A and sirolimus-induced barrier tightening in renal proximal tubular cells. The International Journal of Biochemistry & Cell Biology. 44: 178-88. PMID 22062948 DOI: 10.1016/J.Biocel.2011.10.014  0.771
2011 Malam Z, Parodo J, Waheed F, Szaszi K, Kapus A, Marshall JC. Pre-B cell colony-enhancing factor (PBEF/Nampt/visfatin) primes neutrophils for augmented respiratory burst activity through partial assembly of the NADPH oxidase. Journal of Immunology (Baltimore, Md. : 1950). 186: 6474-84. PMID 21518975 DOI: 10.4049/Jimmunol.1003706  0.746
2011 Kakiashvili E, Dan Q, Vandermeer M, Zhang Y, Waheed F, Pham M, Szászi K. The epidermal growth factor receptor mediates tumor necrosis factor-alpha-induced activation of the ERK/GEF-H1/RhoA pathway in tubular epithelium. The Journal of Biological Chemistry. 286: 9268-79. PMID 21212278 DOI: 10.1074/Jbc.M110.179903  0.77
2011 Papia G, Fan J, Kapus A, Szaszi K, Marshall JC, Tawadros P, Ailenberg M, Rotstein OD. Altered inhibitory κBα expression in LPS-stimulated alveolar macrophages following resuscitated hemorrhagic shock. Shock (Augusta, Ga.). 35: 171-7. PMID 20661182 DOI: 10.1097/Shk.0B013E3181F21D2D  0.371
2010 Waheed F, Speight P, Kawai G, Dan Q, Kapus A, Szászi K. Extracellular signal-regulated kinase and GEF-H1 mediate depolarization-induced Rho activation and paracellular permeability increase. American Journal of Physiology. Cell Physiology. 298: C1376-87. PMID 20237148 DOI: 10.1152/Ajpcell.00408.2009  0.777
2010 Masszi A, Speight P, Charbonney E, Lodyga M, Nakano H, Szászi K, Kapus A. Fate-determining mechanisms in epithelial-myofibroblast transition: major inhibitory role for Smad3. The Journal of Cell Biology. 188: 383-99. PMID 20123992 DOI: 10.1083/Jcb.200906155  0.332
2009 Kakiashvili E, Speight P, Waheed F, Seth R, Lodyga M, Tanimura S, Kohno M, Rotstein OD, Kapus A, Szászi K. GEF-H1 mediates tumor necrosis factor-alpha-induced Rho activation and myosin phosphorylation: role in the regulation of tubular paracellular permeability. The Journal of Biological Chemistry. 284: 11454-66. PMID 19261619 DOI: 10.1074/Jbc.M805933200  0.758
2009 Thirone AC, Speight P, Zulys M, Rotstein OD, Szászi K, Pedersen SF, Kapus A. Hyperosmotic stress induces Rho/Rho kinase/LIM kinase-mediated cofilin phosphorylation in tubular cells: key role in the osmotically triggered F-actin response. American Journal of Physiology. Cell Physiology. 296: C463-75. PMID 19109524 DOI: 10.1152/Ajpcell.00467.2008  0.438
2008 Sebe A, Masszi A, Zulys M, Yeung T, Speight P, Rotstein OD, Nakano H, Mucsi I, Szászi K, Kapus A. Rac, PAK and p38 regulate cell contact-dependent nuclear translocation of myocardin-related transcription factor. Febs Letters. 582: 291-8. PMID 18154735 DOI: 10.1016/J.Febslet.2007.12.021  0.454
2008 Tawadros PS, Jung JJ, Birch SE, Kapus A, Szaszi K, Rotstein OD. QS377. Oxidant-Induced Activation of ERK in RAW 264.7 Macrophages Is Mediated by Sphingosine-1-Phosphate Journal of Surgical Research. 144: 417. DOI: 10.1016/J.Jss.2007.12.631  0.402
2008 Birch SE, Campbell M, Tawadros P, Szaszi K, Kapus A, Rotstein OD. QS375. The Role of p38 in Fer Kinase Dependent Regulation of the Jak/STAT Pathway Journal of Surgical Research. 144: 416-417. DOI: 10.1016/J.Jss.2007.12.629  0.417
2007 Tawadros PS, Powers KA, Yang I, Becker DA, Ginsberg MD, Szaszi K, Kapus A, Rotstein OD. Stilbazulenyl nitrone decreases oxidative stress and reduces lung injury after hemorrhagic shock/resuscitation and LPS. Antioxidants & Redox Signaling. 9: 1971-7. PMID 17715998 DOI: 10.1089/Ars.2007.1765  0.319
2007 Zhao XH, Laschinger C, Arora P, Szászi K, Kapus A, McCulloch CA. Force activates smooth muscle alpha-actin promoter activity through the Rho signaling pathway. Journal of Cell Science. 120: 1801-9. PMID 17456553 DOI: 10.1242/Jcs.001586  0.428
2007 Fan L, Sebe A, Péterfi Z, Masszi A, Thirone AC, Rotstein OD, Nakano H, McCulloch CA, Szászi K, Mucsi I, Kapus A. Cell contact-dependent regulation of epithelial-myofibroblast transition via the rho-rho kinase-phospho-myosin pathway. Molecular Biology of the Cell. 18: 1083-97. PMID 17215519 DOI: 10.1091/Mbc.E06-07-0602  0.443
2007 Hyduk SJ, Chan JR, Duffy ST, Chen M, Peterson MD, Waddell TK, Digby GC, Szaszi K, Kapus A, Cybulsky MI. Phospholipase C, calcium, and calmodulin are critical for alpha4beta1 integrin affinity up-regulation and monocyte arrest triggered by chemoattractants. Blood. 109: 176-84. PMID 16960156 DOI: 10.1182/Blood-2006-01-029199  0.443
2007 Di Ciano-Oliveira C, Thirone AC, Szászi K, Kapus A. Osmotic stress and the cytoskeleton: the R(h)ole of Rho GTPases. Acta Physiologica (Oxford, England). 187: 257-72. PMID 16734763 DOI: 10.1111/J.1748-1716.2006.01535.X  0.386
2007 Tawadros P, Wang Z, Birch S, Szaszi K, Kapus A, Marshall J, Rotstein O. Oxidant-induced TLR4 translocation in murine macrophages is Src kinase dependent Critical Care. 11: P44. DOI: 10.1186/Cc6023  0.391
2006 Kapus A, Szászi K. Coupling between apical and paracellular transport processes. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 84: 870-80. PMID 17215874 DOI: 10.1139/o06-202  0.316
2006 Powers KA, Szászi K, Khadaroo RG, Tawadros PS, Marshall JC, Kapus A, Rotstein OD. Oxidative stress generated by hemorrhagic shock recruits Toll-like receptor 4 to the plasma membrane in macrophages. The Journal of Experimental Medicine. 203: 1951-61. PMID 16847070 DOI: 10.1084/Jem.20060943  0.337
2006 Birch SE, Tawadros P, Szaszi K, Kapus A, Rotstein OD. Fer kinase is a novel regulator of Jak/STAT signaling pathway Journal of the American College of Surgeons. 203: S27-S28. DOI: 10.1016/J.Jamcollsurg.2006.05.067  0.389
2006 Tawadros PS, Birch SE, Zou M, Szaszi K, Kapus A, Rotstein OD. Oxidant-induced Akt phosphorylation in murine macrophages involves ceramide generation through the acid sphingomyelinase pathway Journal of the American College of Surgeons. 203: S26. DOI: 10.1016/J.Jamcollsurg.2006.05.063  0.402
2005 Alexander RT, Furuya W, Szászi K, Orlowski J, Grinstein S. Rho GTPases dictate the mobility of the Na/H exchanger NHE3 in epithelia: role in apical retention and targeting. Proceedings of the National Academy of Sciences of the United States of America. 102: 12253-8. PMID 16103375 DOI: 10.1073/Pnas.0409197102  0.361
2005 Szászi K, Sirokmány G, Di Ciano-Oliveira C, Rotstein OD, Kapus A. Depolarization induces Rho-Rho kinase-mediated myosin light chain phosphorylation in kidney tubular cells. American Journal of Physiology. Cell Physiology. 289: C673-85. PMID 15857905 DOI: 10.1152/Ajpcell.00481.2004  0.49
2005 Szászi K, Jones JJ, Nathens AB, Lo AY, Marsden PA, Kapus A, Rotstein OD. Glutathione depletion inhibits lipopolysaccharide-induced intercellular adhesion molecule 1 synthesis. Free Radical Biology & Medicine. 38: 1333-43. PMID 15855051 DOI: 10.1016/J.Freeradbiomed.2005.01.013  0.452
2005 Di Ciano-Oliveira C, Lodyga M, Fan L, Szászi K, Hosoya H, Rotstein OD, Kapus A. Is myosin light-chain phosphorylation a regulatory signal for the osmotic activation of the Na+-K+-2Cl- cotransporter? American Journal of Physiology. Cell Physiology. 289: C68-81. PMID 15728707 DOI: 10.1152/Ajpcell.00631.2004  0.495
2005 Powers KA, Zurawska J, Szaszi K, Khadaroo RG, Kapus A, Rotstein OD. Hypertonic resuscitation of hemorrhagic shock prevents alveolar macrophage activation by preventing systemic oxidative stress due to gut ischemia/reperfusion. Surgery. 137: 66-74. PMID 15614283 DOI: 10.1016/J.Surg.2004.05.051  0.332
2005 Powers KA, Szaszi K, Khadaroo R, Tawadros P, Marshall JC, Kapus A, Rotstein OD. Hemorrhagic shock recruits Toll-like receptor 4 to the plasma membrane in macrophages: A novel mechanism of cell priming for LPS signaling Journal of the American College of Surgeons. 201: S36. DOI: 10.1016/J.Jamcollsurg.2005.06.070  0.324
2004 Hayashi H, Szászi K, Coady-Osberg N, Furuya W, Bretscher AP, Orlowski J, Grinstein S. Inhibition and redistribution of NHE3, the apical Na+/H+ exchanger, by Clostridium difficile toxin B. The Journal of General Physiology. 123: 491-504. PMID 15078917 DOI: 10.1085/Jgp.200308979  0.436
2003 Di Ciano-Oliveira C, Sirokmány G, Szászi K, Arthur WT, Masszi A, Peterson M, Rotstein OD, Kapus A. Hyperosmotic stress activates Rho: differential involvement in Rho kinase-dependent MLC phosphorylation and NKCC activation. American Journal of Physiology. Cell Physiology. 285: C555-66. PMID 12748065 DOI: 10.1152/Ajpcell.00086.2003  0.504
2002 Hayashi H, Szászi K, Grinstein S. Multiple modes of regulation of Na+/H+ exchangers. Annals of the New York Academy of Sciences. 976: 248-58. PMID 12502567 DOI: 10.1111/J.1749-6632.2002.Tb04747.X  0.396
2002 Szaszi K, Paulsen A, Szabo EZ, Numata M, Grinstein S, Orlowski J. Clathrin-mediated endocytosis and recycling of the neuron-specific Na+/H+ exchanger NHE5 isoform. Regulation by phosphatidylinositol 3'-kinase and the actin cytoskeleton. The Journal of Biological Chemistry. 277: 42623-32. PMID 12205089 DOI: 10.1074/Jbc.M206629200  0.474
2002 Di Ciano C, Nie Z, Szászi K, Lewis A, Uruno T, Zhan X, Rotstein OD, Mak A, Kapus A. Osmotic stress-induced remodeling of the cortical cytoskeleton. American Journal of Physiology. Cell Physiology. 283: C850-65. PMID 12176742 DOI: 10.1152/Ajpcell.00018.2002  0.441
2002 Hayashi H, Szászi K, Coady-Osberg N, Orlowski J, Kinsella JL, Grinstein S. A slow pH-dependent conformational transition underlies a novel mode of activation of the epithelial Na+/H+ exchanger-3 isoform. The Journal of Biological Chemistry. 277: 11090-6. PMID 11792708 DOI: 10.1074/Jbc.M111868200  0.394
2001 Szászi K, Kurashima K, Kaibuchi K, Grinstein S, Orlowski J. Role of the cytoskeleton in mediating cAMP-dependent protein kinase inhibition of the epithelial Na+/H+ exchanger NHE3. The Journal of Biological Chemistry. 276: 40761-8. PMID 11522794 DOI: 10.1074/Jbc.M106724200  0.503
2001 Aharonovitz O, Kapus A, Szászi K, Coady-Osberg N, Jancelewicz T, Orlowski J, Grinstein S. Modulation of Na+/H+ exchange activity by Cl- American Journal of Physiology - Cell Physiology. 281. PMID 11401835 DOI: 10.1152/Ajpcell.2001.281.1.C133  0.414
2000 Szászi K, Grinstein S, Orlowski J, Kapus A. Regulation of the epithelial Na+/H+ exchanger isoform by the cytoskeleton Cellular Physiology and Biochemistry. 10: 265-272. PMID 11125205 DOI: 10.1159/000016358  0.457
2000 Szászi K, Kurashima K, Kapus A, Paulsen A, Kaibuchi K, Grinstein S, Orlowski J. RhoA and rho kinase regulate the epithelial Na+/H+ exchanger NHE3. Role of myosin light chain phosphorylation. The Journal of Biological Chemistry. 275: 28599-606. PMID 10893221 DOI: 10.1016/S1095-6433(00)80283-4  0.491
2000 Szászi K, Kurashima K, Kapus A, Kaibuchi K, Grinstein S, Orlowski J. Rhoa and Rho-kinase regulate the epithelial Na+/H+ exchanger NHE3: role of myosin light chain phosphorylation Comparative Biochemistry and Physiology Part a: Molecular & Integrative Physiology. 126: 143. DOI: 10.1016/s1095-6433(00)80283-4  0.311
2000 Kapus A, Sun J, Szászi K, DiCiano C, Wong T, Mak A, Rotstein O. Cell volume-dependent phosphorylation and reorganization of elements of the cortical cytoskeleton and the cell-cell contacts Comparative Biochemistry and Physiology Part a: Molecular & Integrative Physiology. 126: 75. DOI: 10.1016/S1095-6433(00)80148-8  0.339
1999 Szászi K, Korda A, Wölfl J, Paclet MH, Morel F, Ligeti E. Possible role of RAC-GTPase-activating protein in the termination of superoxide production in phagocytic cells. Free Radical Biology & Medicine. 27: 764-72. PMID 10515580 DOI: 10.1016/S0891-5849(99)00126-4  0.389
1999 Kurashia K, D'Souza S, Szászi K, Ramjeesingh R, Orlowski J, Grinstein S. The apical Na+/H+ exchanger isoform NHE3 is regulated by the actin cytoskeleton Journal of Biological Chemistry. 274: 29843-29849. PMID 10514464 DOI: 10.1074/Jbc.274.42.29843  0.381
1999 Kapus A, Szászi K, Sun J, Rizoli S, Rotstein OD. Cell shrinkage regulates Src kinases and induces tyrosine phosphorylation of cortactin, independent of the osmotic regulation of Na+/H+ exchangers. The Journal of Biological Chemistry. 274: 8093-102. PMID 10075710 DOI: 10.1074/Jbc.274.12.8093  0.488
1997 Szászi K, Buday L, Kapus A. Shrinkage-induced Protein Tyrosine Phosphorylation in Chinese Hamster Ovary Cells Journal of Biological Chemistry. 272: 16670-16678. PMID 9195983 DOI: 10.1074/Jbc.272.26.16670  0.447
1996 Káldi K, Szászi K, Koncz G, Suszták K, Ligeti E. Arachidonic acid activatable electrogenic H+ transport in the absence of cytochrome b558 in human T lymphocytes. Febs Letters. 381: 156-60. PMID 8641428 DOI: 10.1016/0014-5793(96)00105-6  0.309
1994 Káldi K, Szászi K, Suszták K, Kapus A, Ligeti E. Lymphocytes possess an electrogenic H(+)-transporting pathway in their plasma membrane. The Biochemical Journal. 329-34. PMID 7519007 DOI: 10.1042/Bj3010329  0.348
1992 Kapus A, Szászi K, Ligeti E. Phorbol 12-myristate 13-acetate activates an electrogenic H(+)-conducting pathway in the membrane of neutrophils. The Biochemical Journal. 697-701. PMID 1371386 DOI: 10.1042/Bj2810697  0.406
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