| Year |
Citation |
Score |
| 2017 |
Meyers K, Cogan DA, Burke J, Arenas R, Balestra M, Brown NF, Cerny MA, Clifford HE, Colombo F, Fader L, Frederick KS, Guo X, Hornberger KR, Kugler S, Lord J, et al. Dihydrobenzisoxazole-4-one compounds are novel selective inhibitors of aldosterone synthase (CYP11B2) with in vivo activity. Bioorganic & Medicinal Chemistry Letters. PMID 29254646 DOI: 10.1016/J.Bmcl.2017.12.015 |
0.42 |
|
| 2016 |
Abeywardane A, Caviness G, Choi Y, Cogan D, Gao A, Goldberg D, Heim-Riether A, Jeanfavre D, Klein E, Kowalski JA, Mao W, Miller C, Moss N, Ramsden P, Raymond E, et al. N-Arylsulfonyl-α-amino carboxamides are potent and selective inhibitors of the chemokine receptor CCR10 that show efficacy in the murine DNFB model of contact hypersensitivity. Bioorganic & Medicinal Chemistry Letters. PMID 27692854 DOI: 10.1016/J.Bmcl.2016.09.047 |
0.4 |
|
| 2016 |
Weldon SM, Cerny MA, Gueneva-Boucheva K, Cogan D, Guo X, Moss N, Parmentier JH, Richman J, Reinhart GA, Brown NF. Selectivity of BI 689648 - A Novel, Highly Selective Aldosterone Synthase Inhibitor: Comparison to FAD286 and LCI699 in Non-Human Primates. The Journal of Pharmacology and Experimental Therapeutics. PMID 27481775 DOI: 10.1124/Jpet.116.236463 |
0.377 |
|
| 2012 |
Moss N, Xiong Z, Burke M, Cogan D, Gao DA, Haverty K, Heim-Riether A, Hickey ER, Nagaraja R, Netherton M, O'Shea K, Ramsden P, Schwartz R, Shih DT, Ward Y, et al. Exploration of cathepsin S inhibitors characterized by a triazole P1-P2 amide replacement. Bioorganic & Medicinal Chemistry Letters. 22: 7189-93. PMID 23084902 DOI: 10.1016/J.Bmcl.2012.09.054 |
0.398 |
|
| 2012 |
Boyer SJ, Burke J, Guo X, Kirrane TM, Snow RJ, Zhang Y, Sarko C, Soleymanzadeh L, Swinamer A, Westbrook J, Dicapua F, Padyana A, Cogan D, Gao A, Xiong Z, et al. Indole RSK inhibitors. Part 1: discovery and initial SAR. Bioorganic & Medicinal Chemistry Letters. 22: 733-7. PMID 22100312 DOI: 10.1016/J.Bmcl.2011.10.030 |
0.418 |
|
| 2009 |
Moss N, Choi Y, Cogan D, Flegg A, Kahrs A, Loke P, Meyn O, Nagaraja R, Napier S, Parker A, Thomas Peterson J, Ramsden P, Sarko C, Skow D, Tomlinson J, et al. A new class of 5-HT2B antagonists possesses favorable potency, selectivity, and rat pharmacokinetic properties. Bioorganic & Medicinal Chemistry Letters. 19: 2206-10. PMID 19307114 DOI: 10.1016/J.Bmcl.2009.02.126 |
0.388 |
|
| 2008 |
Xiong Z, Gao DA, Cogan DA, Goldberg DR, Hao MH, Moss N, Pack E, Pargellis C, Skow D, Trieselmann T, Werneburg B, White A. Synthesis and SAR studies of indole-based MK2 inhibitors. Bioorganic & Medicinal Chemistry Letters. 18: 1994-9. PMID 18291646 DOI: 10.1016/j.bmcl.2008.01.119 |
0.344 |
|
| 2008 |
Goldberg DR, Choi Y, Cogan D, Corson M, DeLeon R, Gao A, Gruenbaum L, Hao MH, Joseph D, Kashem MA, Miller C, Moss N, Netherton MR, Pargellis CP, Pelletier J, et al. Pyrazinoindolone inhibitors of MAPKAP-K2. Bioorganic & Medicinal Chemistry Letters. 18: 938-41. PMID 18221871 DOI: 10.1016/J.Bmcl.2007.12.037 |
0.333 |
|
| 2007 |
Cywin CL, Dahmann G, Prokopowicz AS, Young ER, Magolda RL, Cardozo MG, Cogan DA, Disalvo D, Ginn JD, Kashem MA, Wolak JP, Homon CA, Farrell TM, Grbic H, Hu H, et al. Discovery of potent and selective PKC-theta inhibitors. Bioorganic & Medicinal Chemistry Letters. 17: 225-30. PMID 17055721 DOI: 10.1016/J.Bmcl.2006.09.056 |
0.486 |
|
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