| Year |
Citation |
Score |
| 2022 |
Showpnil IA, Selich-Anderson J, Taslim C, Boone MA, Crow JC, Theisen ER, Lessnick SL. EWS/FLI mediated reprogramming of 3D chromatin promotes an altered transcriptional state in Ewing sarcoma. Nucleic Acids Research. PMID 36124657 DOI: 10.1093/nar/gkac747 |
0.372 |
|
| 2022 |
Shulman DS, Whittle SB, Surdez D, Bailey KM, de Álava E, Yustein JT, Shlien A, Hayashi M, Bishop AJR, Crompton BD, DuBois SG, Shukla N, Leavey PJ, Lessnick SL, Kovar H, et al. An international working group consensus report for the prioritization of molecular biomarkers for Ewing sarcoma. Npj Precision Oncology. 6: 65. PMID 36115869 DOI: 10.1038/s41698-022-00307-2 |
0.311 |
|
| 2021 |
Boone MA, Taslim C, Crow JC, Selich-Anderson J, Watson M, Heppner P, Hamill J, Wood AC, Lessnick SL, Winstanley M. Identification of a novel FUS/ETV4 fusion and comparative analysis with other Ewing sarcoma fusion proteins. Molecular Cancer Research : McR. PMID 34465585 DOI: 10.1158/1541-7786.MCR-21-0354 |
0.356 |
|
| 2021 |
Boone MA, Taslim C, Crow JC, Selich-Anderson J, Byrum AK, Showpnil IA, Sunkel BD, Wang M, Stanton BZ, Theisen ER, Lessnick SL. The FLI portion of EWS/FLI contributes a transcriptional regulatory function that is distinct and separable from its DNA-binding function in Ewing sarcoma. Oncogene. PMID 34145397 DOI: 10.1038/s41388-021-01876-5 |
0.322 |
|
| 2020 |
Theisen ER, Selich-Anderson J, Miller KR, Tanner JM, Taslim C, Pishas KI, Sharma S, Lessnick SL. Chromatin profiling reveals relocalization of lysine-specific demethylase 1 by an oncogenic fusion protein. Epigenetics. 1-20. PMID 32842875 DOI: 10.1080/15592294.2020.1805678 |
0.381 |
|
| 2020 |
Showpnil IA, Miller KR, Taslim C, Pishas KI, Lessnick SL, Theisen ER. Mapping the Structure-Function Relationships of Disordered Oncogenic Transcription Factors Using Transcriptomic Analysis. Journal of Visualized Experiments : Jove. PMID 32658189 DOI: 10.3791/61564 |
0.348 |
|
| 2020 |
Luo W, Xu C, Phillips S, Gardenswartz A, Rosenblum JM, Ayello J, Lessnick SL, Hao HX, Cairo MS. Protein phosphatase 1 regulatory subunit 1A regulates cell cycle progression in Ewing sarcoma. Oncotarget. 11: 1691-1704. PMID 32477459 DOI: 10.18632/oncotarget.27571 |
0.377 |
|
| 2019 |
Patel PO, Pishas KI, Taslim C, Selich-Anderson J, Theisen ER, Lessnick SL. Investigating the role of LSD2 as an epigenetic regulator in Ewing sarcoma. Oncotarget. 10: 3865-3878. PMID 31231465 DOI: 10.18632/oncotarget.26988 |
0.355 |
|
| 2019 |
Theisen ER, Miller KR, Showpnil IA, Taslim C, Pishas KI, Lessnick SL. Transcriptomic analysis functionally maps the intrinsically disordered domain of EWS/FLI and reveals novel transcriptional dependencies for oncogenesis. Genes & Cancer. 10: 21-38. PMID 30899417 DOI: 10.18632/genesandcancer.188 |
0.313 |
|
| 2019 |
Harlow ML, Chasse MH, Boguslawski EA, Sorensen KM, Gedminas JM, Kitchen-Goosen SM, Rothbart SB, Taslim C, Lessnick SL, Peck AS, Madaj ZB, Bowman MJ, Grohar PJ. Trabectedin Inhibits EWS-FLI1 and Evicts SWI/SNF from Chromatin in a Schedule Dependent Manner. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 30723142 DOI: 10.1158/1078-0432.Ccr-18-3511 |
0.301 |
|
| 2018 |
Gorthi A, Romero JC, Loranc E, Cao L, Lawrence LA, Goodale E, Iniguez AB, Bernard X, Masamsetti VP, Roston S, Lawlor ER, Toretsky JA, Stegmaier K, Lessnick SL, Chen Y, et al. EWS-FLI1 increases transcription to cause R-loops and block BRCA1 repair in Ewing sarcoma. Nature. PMID 29513652 DOI: 10.1038/Nature25748 |
0.326 |
|
| 2017 |
Johnson KM, Mahler NR, Saund RS, Theisen ER, Taslim C, Callender NW, Crow JC, Miller KR, Lessnick SL. Role for the EWS domain of EWS/FLI in binding GGAA-microsatellites required for Ewing sarcoma anchorage independent growth. Proceedings of the National Academy of Sciences of the United States of America. PMID 28847958 DOI: 10.1073/pnas.1701872114 |
0.306 |
|
| 2016 |
Sankar S, Bell R, Stephens B, Zhuo R, Sharma S, Bearss DJ, Lessnick SL. Mechanism and relevance of EWS/FLI-mediated transcriptional repression in Ewing sarcoma. Oncogene. PMID 27345405 DOI: 10.1038/onc.2016.142 |
0.613 |
|
| 2016 |
Osgood CL, Maloney N, Kidd CG, Kitchen-Goosen SM, Segars LE, Gebregiorgis M, Woldemichael GM, He M, Sankar S, Lessnick SL, Kang MH, Smith MA, Turner L, Madaj ZB, Winn ME, et al. Identification of mithramycin analogs with improved targeting of the EWS-FLI1 transcription factor. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 26979396 DOI: 10.1158/1078-0432.Ccr-15-2624 |
0.611 |
|
| 2016 |
Theisen ER, Pishas KI, Saund RS, Lessnick SL. Therapeutic opportunities in Ewing sarcoma: EWS-FLI inhibition via LSD1 targeting. Oncotarget. PMID 26848860 DOI: 10.18632/oncotarget.7124 |
0.421 |
|
| 2016 |
Kovar H, Amatruda J, Brunet E, Burdach S, Cidre-Aranaz F, de Alava E, Dirksen U, van der Ent W, Grohar P, Grünewald TG, Helman L, Houghton P, Iljin K, Korsching E, Ladanyi M, ... ... Lessnick S, et al. The second European interdisciplinary Ewing sarcoma research summit - A joint effort to deconstructing the multiple layers of a complex disease. Oncotarget. PMID 26802024 DOI: 10.18632/Oncotarget.6937 |
0.34 |
|
| 2015 |
Fadul J, Bell R, Hoffman LM, Beckerle MC, Engel ME, Lessnick SL. EWS/FLI utilizes NKX2-2 to repress mesenchymal features of Ewing sarcoma. Genes & Cancer. 6: 129-43. PMID 26000096 |
0.359 |
|
| 2015 |
Lerman DM, Monument MJ, McIlvaine E, Liu XQ, Huang D, Monovich L, Beeler N, Gorlick RG, Marina NM, Womer RB, Bridge JA, Krailo MD, Randall RL, Lessnick SL. Tumoral TP53 and/or CDKN2A alterations are not reliable prognostic biomarkers in patients with localized Ewing sarcoma: a report from the Children's Oncology Group. Pediatric Blood & Cancer. 62: 759-65. PMID 25464386 DOI: 10.1002/Pbc.25340 |
0.377 |
|
| 2015 |
Abbott D, Randall RL, Schiffman J, Lessnick S, Cannon-Albright LA. Abstract 2748: A population-based survey of excess cancers observed in Ewing's sarcoma and in their first-, second-, and third-degree relatives Cancer Research. 75: 2748-2748. DOI: 10.1158/1538-7445.Am2015-2748 |
0.309 |
|
| 2014 |
Zhuo R, Kosak KM, Sankar S, Wiles ET, Sun Y, Zhang J, Ayello J, Prestwich GD, Shami PJ, Cairo MS, Lessnick SL, Luo W. Targeting Glutathione S-transferase M4 in Ewing sarcoma. Frontiers in Pediatrics. 2: 83. PMID 25147782 DOI: 10.3389/Fped.2014.00083 |
0.682 |
|
| 2014 |
Monument MJ, Johnson KM, McIlvaine E, Abegglen L, Watkins WS, Jorde LB, Womer RB, Beeler N, Monovich L, Lawlor ER, Bridge JA, Schiffman JD, Krailo MD, Randall RL, Lessnick SL. Clinical and biochemical function of polymorphic NR0B1 GGAA-microsatellites in Ewing sarcoma: a report from the Children's Oncology Group. Plos One. 9: e104378. PMID 25093581 DOI: 10.1371/Journal.Pone.0104378 |
0.43 |
|
| 2014 |
Chaturvedi A, Hoffman LM, Jensen CC, Lin YC, Grossmann AH, Randall RL, Lessnick SL, Welm AL, Beckerle MC. Molecular dissection of the mechanism by which EWS/FLI expression compromises actin cytoskeletal integrity and cell adhesion in Ewing sarcoma. Molecular Biology of the Cell. 25: 2695-709. PMID 25057021 DOI: 10.1091/Mbc.E14-01-0007 |
0.45 |
|
| 2014 |
Sankar S, Theisen ER, Bearss J, Mulvihill T, Hoffman LM, Sorna V, Beckerle MC, Sharma S, Lessnick SL. Reversible LSD1 inhibition interferes with global EWS/ETS transcriptional activity and impedes Ewing sarcoma tumor growth. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 20: 4584-97. PMID 24963049 DOI: 10.1158/1078-0432.Ccr-14-0072 |
0.703 |
|
| 2014 |
Kumar P P, Emechebe U, Smith R, Franklin S, Moore B, Yandell M, Lessnick SL, Moon AM. Coordinated control of senescence by lncRNA and a novel T-box3 co-repressor complex. Elife. 3. PMID 24876127 DOI: 10.7554/Elife.02805 |
0.356 |
|
| 2013 |
Wiles ET, Bell R, Thomas D, Beckerle M, Lessnick SL. ZEB2 Represses the Epithelial Phenotype and Facilitates Metastasis in Ewing Sarcoma. Genes & Cancer. 4: 486-500. PMID 24386509 DOI: 10.1177/1947601913506115 |
0.32 |
|
| 2013 |
Sankar S, Gomez NC, Bell R, Patel M, Davis IJ, Lessnick SL, Luo W. EWS and RE1-Silencing Transcription Factor Inhibit Neuronal Phenotype Development and Oncogenic Transformation in Ewing Sarcoma. Genes & Cancer. 4: 213-23. PMID 24069508 DOI: 10.1177/1947601913489569 |
0.691 |
|
| 2013 |
Sankar S, Tanner JM, Bell R, Chaturvedi A, Randall RL, Beckerle MC, Lessnick SL. A novel role for keratin 17 in coordinating oncogenic transformation and cellular adhesion in Ewing sarcoma. Molecular and Cellular Biology. 33: 4448-60. PMID 24043308 DOI: 10.1128/Mcb.00241-13 |
0.663 |
|
| 2013 |
Wiles ET, Lui-Sargent B, Bell R, Lessnick SL. BCL11B is up-regulated by EWS/FLI and contributes to the transformed phenotype in Ewing sarcoma. Plos One. 8: e59369. PMID 23527175 DOI: 10.1371/Journal.Pone.0059369 |
0.524 |
|
| 2013 |
Gorlick R, Janeway K, Lessnick S, Randall RL, Marina N. Children's oncology group's 2013 blueprint for research: Bone tumors Pediatric Blood and Cancer. 60: 1009-1015. PMID 23255238 DOI: 10.1002/Pbc.24429 |
0.349 |
|
| 2013 |
Sankar S, Bell R, Stephens B, Zhuo R, Sharma S, Bearss DJ, Lessnick SL. Mechanism and relevance of EWS/FLI-mediated transcriptional repression in Ewing sarcoma. Oncogene. 32: 5089-100. PMID 23178492 DOI: 10.1038/Onc.2012.525 |
0.702 |
|
| 2012 |
Monument MJ, Johnson KM, Grossmann AH, Schiffman JD, Randall RL, Lessnick SL. Microsatellites with macro-influence in ewing sarcoma. Genes. 3: 444-60. PMID 24704979 DOI: 10.3390/genes3030444 |
0.382 |
|
| 2012 |
Chaturvedi A, Hoffman LM, Welm AL, Lessnick SL, Beckerle MC. The EWS/FLI Oncogene Drives Changes in Cellular Morphology, Adhesion, and Migration in Ewing Sarcoma. Genes & Cancer. 3: 102-16. PMID 23050043 DOI: 10.1177/1947601912457024 |
0.46 |
|
| 2012 |
Evans CH, Liu F, Porter RM, O'Sullivan RP, Merghoub T, Lunsford EP, Robichaud K, Van Valen F, Lessnick SL, Gebhardt MC, Wells JW. EWS-FLI-1-targeted cytotoxic T-cell killing of multiple tumor types belonging to the Ewing sarcoma family of tumors. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 5341-51. PMID 22879388 DOI: 10.1158/1078-0432.CCR-12-1985 |
0.332 |
|
| 2012 |
Jahromi MS, Putnam AR, Druzgal C, Wright J, Spraker-Perlman H, Kinsey M, Zhou H, Boucher KM, Randall RL, Jones KB, Lucas D, Rosenberg A, Thomas D, Lessnick SL, Schiffman JD. Molecular inversion probe analysis detects novel copy number alterations in Ewing sarcoma. Cancer Genetics. 205: 391-404. PMID 22868000 DOI: 10.1016/J.Cancergen.2012.05.012 |
0.422 |
|
| 2012 |
Beck R, Monument MJ, Watkins WS, Smith R, Boucher KM, Schiffman JD, Jorde LB, Randall RL, Lessnick SL. EWS/FLI-responsive GGAA microsatellites exhibit polymorphic differences between European and African populations. Cancer Genetics. 205: 304-12. PMID 22749036 DOI: 10.1016/J.Cancergen.2012.04.004 |
0.399 |
|
| 2012 |
Spraker HL, Price SL, Chaturvedi A, Schiffman JD, Jones KB, Lessnick SL, Beckerle M, Randall RL. The clone wars - revenge of the metastatic rogue state: the sarcoma paradigm. Frontiers in Oncology. 2: 2. PMID 22649772 DOI: 10.3389/Fonc.2012.00002 |
0.424 |
|
| 2012 |
Luo W, Milash B, Dalley B, Smith R, Zhou H, Dutrow N, Cairns BR, Lessnick SL. Antibody detection of translocations in Ewing sarcoma. Embo Molecular Medicine. 4: 453-61. PMID 22419563 DOI: 10.1002/Emmm.201200225 |
0.341 |
|
| 2012 |
Lessnick SL, Ladanyi M. Molecular pathogenesis of Ewing sarcoma: new therapeutic and transcriptional targets. Annual Review of Pathology. 7: 145-59. PMID 21942527 DOI: 10.1146/Annurev-Pathol-011110-130237 |
0.483 |
|
| 2012 |
DuBois SG, Goldsby R, Segal M, Woo J, Copren K, Kane JP, Pullinger CR, Matthay KK, Witte J, Lessnick SL, Robison LL, Bhatia S, Strong LC. Evaluation of polymorphisms in EWSR1 and risk of Ewing sarcoma: a report from the Childhood Cancer Survivor Study. Pediatric Blood & Cancer. 59: 52-6. PMID 21793187 DOI: 10.1002/Pbc.23263 |
0.351 |
|
| 2012 |
Monument MJ, Beck R, Watkins WS, Jorde LB, Randall RL, Lessnick SL. Abstract 3979: Ethnic polymorphisms in the GGAA microsatellite response element of key Ewing's sarcoma EWS/FLI-target genes Cancer Research. 72: 3979-3979. DOI: 10.1158/1538-7445.Am2012-3979 |
0.41 |
|
| 2011 |
Joyner DE, Jones KB, Lessnick SL, Schiffman JD, Randall RL. Potential for modulation of the fas apoptotic pathway by epidermal growth factor in sarcomas. Sarcoma. 2011: 847409. PMID 22135505 DOI: 10.1155/2011/847409 |
0.323 |
|
| 2011 |
Sankar S, Lessnick SL. Promiscuous partnerships in Ewing's sarcoma. Cancer Genetics. 204: 351-65. PMID 21872822 DOI: 10.1016/J.Cancergen.2011.07.008 |
0.731 |
|
| 2011 |
Kowalewski AA, Randall RL, Lessnick SL. Cell Cycle Deregulation in Ewing's Sarcoma Pathogenesis. Sarcoma. 2011: 598704. PMID 21052502 DOI: 10.1155/2011/598704 |
0.529 |
|
| 2010 |
Gangwal K, Close D, Enriquez CA, Hill CP, Lessnick SL. Emergent Properties of EWS/FLI Regulation via GGAA Microsatellites in Ewing's Sarcoma. Genes & Cancer. 1: 177-187. PMID 20827386 DOI: 10.1177/1947601910361495 |
0.442 |
|
| 2010 |
Toomey EC, Schiffman JD, Lessnick SL. Recent advances in the molecular pathogenesis of Ewing's sarcoma. Oncogene. 29: 4504-16. PMID 20543858 DOI: 10.1038/Onc.2010.205 |
0.686 |
|
| 2010 |
van Doorninck JA, Ji L, Schaub B, Shimada H, Wing MR, Krailo MD, Lessnick SL, Marina N, Triche TJ, Sposto R, Womer RB, Lawlor ER. Current treatment protocols have eliminated the prognostic advantage of type 1 fusions in Ewing sarcoma: a report from the Children's Oncology Group. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 28: 1989-94. PMID 20308669 DOI: 10.1200/Jco.2009.24.5845 |
0.326 |
|
| 2010 |
Randall RL, Lessnick SL, Jones KB, Gouw LG, Cummings JE, Cannon-Albright L, Schiffman JD. Is There a Predisposition Gene for Ewing's Sarcoma? Journal of Oncology. 2010: 397632. PMID 20300555 DOI: 10.1155/2010/397632 |
0.513 |
|
| 2009 |
Kinsey M, Smith R, Iyer AK, McCabe ER, Lessnick SL. EWS/FLI and its downstream target NR0B1 interact directly to modulate transcription and oncogenesis in Ewing's sarcoma. Cancer Research. 69: 9047-55. PMID 19920188 DOI: 10.1158/0008-5472.Can-09-1540 |
0.444 |
|
| 2009 |
Luo W, Gangwal K, Sankar S, Boucher KM, Thomas D, Lessnick SL. GSTM4 is a microsatellite-containing EWS/FLI target involved in Ewing's sarcoma oncogenesis and therapeutic resistance. Oncogene. 28: 4126-32. PMID 19718047 DOI: 10.1038/Onc.2009.262 |
0.729 |
|
| 2009 |
Lessnick SL, Dei Tos AP, Sorensen PH, Dileo P, Baker LH, Ferrari S, Hall KS. Small round cell sarcomas. Seminars in Oncology. 36: 338-46. PMID 19664494 DOI: 10.1053/J.Seminoncol.2009.06.006 |
0.415 |
|
| 2009 |
Braun BS, Lessnick SL. Pediatric malignancies: update on sarcomas and leukemia development in children. Current Opinion in Genetics & Development. 19: 92-6. PMID 19186049 DOI: 10.1016/J.Gde.2008.12.005 |
0.43 |
|
| 2008 |
Gangwal K, Lessnick SL. Microsatellites are EWS/FLI response elements: genomic "junk" is EWS/FLI's treasure. Cell Cycle (Georgetown, Tex.). 7: 3127-32. PMID 18927503 DOI: 10.4161/cc.7.20.6892 |
0.488 |
|
| 2008 |
Gangwal K, Sankar S, Hollenhorst PC, Kinsey M, Haroldsen SC, Shah AA, Boucher KM, Watkins WS, Jorde LB, Graves BJ, Lessnick SL. Microsatellites as EWS/FLI response elements in Ewing's sarcoma. Proceedings of the National Academy of Sciences of the United States of America. 105: 10149-54. PMID 18626011 DOI: 10.1073/Pnas.0801073105 |
0.707 |
|
| 2008 |
Meyer JS, Nadel HR, Marina N, Womer RB, Brown KL, Eary JF, Gorlick R, Grier HE, Randall RL, Lawlor ER, Lessnick SL, Schomberg PJ, Kailo MD. Imaging guidelines for children with Ewing sarcoma and osteosarcoma: a report from the Children's Oncology Group Bone Tumor Committee. Pediatric Blood & Cancer. 51: 163-70. PMID 18454470 DOI: 10.1002/Pbc.21596 |
0.317 |
|
| 2008 |
Owen LA, Kowalewski AA, Lessnick SL. EWS/FLI mediates transcriptional repression via NKX2.2 during oncogenic transformation in Ewing's sarcoma Plos One. 3. PMID 18414662 DOI: 10.1371/journal.pone.0001965 |
0.731 |
|
| 2008 |
Hancock JD, Lessnick SL. A transcriptional profiling meta-analysis reveals a core EWS-FLI gene expression signature. Cell Cycle (Georgetown, Tex.). 7: 250-6. PMID 18256529 DOI: 10.4161/Cc.7.2.5229 |
0.507 |
|
| 2008 |
Meyer JS, Nadel HR, Marina N, Womer RB, Brown KLB, Eary JF, Gorlick R, Grier HE, Randall RL, Lawlor ER, Lessnick SL, Schomberg PJ, Kailo MD. Response to "imaging guidelines for children with Ewing sarcoma and osteosarcoma: A report from the Children's Oncology Group Bone Tumor Committee" Pediatric Blood and Cancer. 51: 839-840. DOI: 10.1002/Pbc.21724 |
0.334 |
|
| 2007 |
Potikyan G, Savene RO, Gaulden JM, France KA, Zhou Z, Kleinerman ES, Lessnick SL, Denny CT. EWS/FLI1 regulates tumor angiogenesis in Ewing's sarcoma via suppression of thrombospondins. Cancer Research. 67: 6675-84. PMID 17638877 DOI: 10.1158/0008-5472.Can-06-4140 |
0.753 |
|
| 2007 |
Stegmaier K, Wong JS, Ross KN, Chow KT, Peck D, Wright RD, Lessnick SL, Kung AL, Golub TR. Signature-based small molecule screening identifies cytosine arabinoside as an EWS/FLI modulator in Ewing sarcoma. Plos Medicine. 4: e122. PMID 17425403 DOI: 10.1371/Journal.Pmed.0040122 |
0.53 |
|
| 2007 |
Haldar M, Hancock JD, Coffin CM, Lessnick SL, Capecchi MR. A conditional mouse model of synovial sarcoma: insights into a myogenic origin. Cancer Cell. 11: 375-88. PMID 17418413 DOI: 10.1016/J.Ccr.2007.01.016 |
0.394 |
|
| 2006 |
Braunreiter CL, Hancock JD, Coffin CM, Boucher KM, Lessnick SL. Expression of EWS-ETS fusions in NIH3T3 cells reveals significant differences to Ewing's sarcoma. Cell Cycle (Georgetown, Tex.). 5: 2753-9. PMID 17172842 DOI: 10.4161/Cc.5.23.3505 |
0.458 |
|
| 2006 |
Kinsey M, Smith R, Lessnick SL. NR0B1 is required for the oncogenic phenotype mediated by EWS/FLI in Ewing's sarcoma. Molecular Cancer Research : McR. 4: 851-9. PMID 17114343 DOI: 10.1158/1541-7786.Mcr-06-0090 |
0.558 |
|
| 2006 |
Owen LA, Lessnick SL. Identification of target genes in their native cellular context: An analysis of EWS/FLI in Ewing's sarcoma Cell Cycle. 5: 2049-2053. PMID 16969112 DOI: 10.4161/Cc.5.18.3213 |
0.732 |
|
| 2006 |
Davis IJ, Kim JJ, Ozsolak F, Widlund HR, Rozenblatt-Rosen O, Granter SR, Du J, Fletcher JA, Denny CT, Lessnick SL, Linehan WM, Kung AL, Fisher DE. Oncogenic MITF dysregulation in clear cell sarcoma: defining the MiT family of human cancers. Cancer Cell. 9: 473-84. PMID 16766266 DOI: 10.1016/J.Ccr.2006.04.021 |
0.702 |
|
| 2006 |
Smith R, Owen LA, Trem DJ, Wong JS, Whangbo JS, Golub TR, Lessnick SL. Expression profiling of EWS/FLI identifies NKX2.2 as a critical target gene in Ewing's sarcoma. Cancer Cell. 9: 405-16. PMID 16697960 DOI: 10.1016/J.Ccr.2006.04.004 |
0.787 |
|
| 2003 |
Gozani O, Karuman P, Jones DR, Ivanov D, Cha J, Lugovskoy AA, Baird CL, Zhu H, Field SJ, Lessnick SL, Villasenor J, Mehrotra B, Chen J, Rao VR, Brugge JS, et al. The PHD finger of the chromatin-associated protein ING2 functions as a nuclear phosphoinositide receptor. Cell. 114: 99-111. PMID 12859901 DOI: 10.1016/S0092-8674(03)00480-X |
0.353 |
|
| 2003 |
Dolma S, Lessnick SL, Hahn WC, Stockwell BR. Identification of genotype-selective antitumor agents using synthetic lethal chemical screening in engineered human tumor cells. Cancer Cell. 3: 285-96. PMID 12676586 DOI: 10.1016/S1535-6108(03)00050-3 |
0.318 |
|
| 2002 |
Widlund HR, Horstmann MA, Price ER, Cui J, Lessnick SL, Wu M, He X, Fisher DE. Beta-catenin-induced melanoma growth requires the downstream target Microphthalmia-associated transcription factor. The Journal of Cell Biology. 158: 1079-87. PMID 12235125 DOI: 10.1083/Jcb.200202049 |
0.395 |
|
| 2002 |
Lessnick SL, Dacwag CS, Golub TR. The Ewing's sarcoma oncoprotein EWS/FLI induces a p53-dependent growth arrest in primary human fibroblasts. Cancer Cell. 1: 393-401. PMID 12086853 DOI: 10.1016/S1535-6108(02)00056-9 |
0.625 |
|
| 1995 |
Braun BS, Frieden R, Lessnick SL, May WA, Denny CT. Identification of target genes for the Ewing's sarcoma EWS/FLI fusion protein by representational difference analysis. Molecular and Cellular Biology. 15: 4623-30. PMID 7623854 DOI: 10.1128/Mcb.15.8.4623 |
0.727 |
|
| 1994 |
Sorensen PH, Lessnick SL, Lopez-Terrada D, Liu XF, Triche TJ, Denny CT. A second Ewing's sarcoma translocation, t(21;22), fuses the EWS gene to another ETS-family transcription factor, ERG. Nature Genetics. 6: 146-51. PMID 8162068 DOI: 10.1038/Ng0294-146 |
0.698 |
|
| 1993 |
May WA, Gishizky ML, Lessnick SL, Lunsford LB, Lewis BC, Delattre O, Zucman J, Thomas G, Denny CT. Ewing sarcoma 11;22 translocation produces a chimeric transcription factor that requires the DNA-binding domain encoded by FLI1 for transformation. Proceedings of the National Academy of Sciences of the United States of America. 90: 5752-6. PMID 8516324 DOI: 10.1073/Pnas.90.12.5752 |
0.722 |
|
| 1993 |
May WA, Lessnick SL, Braun BS, Klemsz M, Lewis BC, Lunsford LB, Hromas R, Denny CT. The Ewing's sarcoma EWS/FLI-1 fusion gene encodes a more potent transcriptional activator and is a more powerful transforming gene than FLI-1. Molecular and Cellular Biology. 13: 7393-8. PMID 8246959 DOI: 10.1128/mcb.13.12.7393-7398.1993 |
0.762 |
|
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