Paul Jedlicka - Publications

Affiliations: 
Cancer Biology University of Colorado Anschutz Medical Campus, Denver, Aurora, CO 
Area:
General Biology, Molecular Biology

63 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Sobral LM, Hicks HM, Parrish JK, McCann TS, Hsieh J, Goodspeed A, Costello JC, Black JC, Jedlicka P. KDM3A/Ets1 epigenetic axis contributes to PAX3/FOXO1-driven and independent disease-promoting gene expression in fusion-positive Rhabdomyosarcoma. Molecular Oncology. PMID 32697014 DOI: 10.1002/1878-0261.12769  0.323
2020 Sobral LM, Sechler M, Parrish JK, McCann TS, Jones KL, Black JC, Jedlicka P. KDM3A/Ets1/MCAM axis promotes growth and metastatic properties in Rhabdomyosarcoma. Genes & Cancer. 11: 53-65. PMID 32577157 DOI: 10.18632/Genesandcancer.200  0.386
2020 Olli KE, Rapp C, O'Connell L, Collins CB, McNamee EN, Jensen O, Jedlicka P, Allison KC, Goldberg MS, Gerich ME, Frank DN, Ir D, Robertson CE, Evans CM, Aherne CM. Muc5ac Expression Protects the Colonic Barrier in Experimental Colitis. Inflammatory Bowel Diseases. PMID 32385500 DOI: 10.1093/Ibd/Izaa064  0.305
2019 McCann TS, Sobral LM, Self C, Hsieh J, Sechler M, Jedlicka P. Biology and targeting of the Jumonji-domain histone demethylase family in childhood neoplasia: a preclinical overview. Expert Opinion On Therapeutic Targets. PMID 30759030 DOI: 10.1080/14728222.2019.1580692  0.313
2018 Aherne CM, Collins CB, Rapp CR, Olli KE, Perrenoud L, Jedlicka P, Bowser JL, Mills TW, Karmouty-Quintana H, Blackburn MR, Eltzschig HK. Coordination of ENT2-dependent adenosine transport and signaling dampens mucosal inflammation. Jci Insight. 3. PMID 30333323 DOI: 10.1172/Jci.Insight.121521  0.346
2018 Sanctuary MR, Huang RH, Jones AA, Luck ME, Aherne CM, Jedlicka P, de Zoeten EF, Collins CB. miR-106a deficiency attenuates inflammation in murine IBD models. Mucosal Immunology. PMID 30327532 DOI: 10.1038/S41385-018-0091-7  0.429
2018 Parrish JK, McCann TS, Sechler M, Sobral LM, Ren W, Jones KL, Tan AC, Jedlicka P. The Jumonji-domain histone demethylase inhibitor JIB-04 deregulates oncogenic programs and increases DNA damage in Ewing Sarcoma, resulting in impaired cell proliferation and survival, and reduced tumor growth. Oncotarget. 9: 33110-33123. PMID 30237855 DOI: 10.18632/Oncotarget.26011  0.349
2018 Collins CB, Puthoor PR, Nguyen TT, Jedlicka P, Friedman JE, de Zoeten EF. C/EBPβ deletion promotes expansion of poorly functional intestinal regulatory T cells. Journal of Crohn's & Colitis. PMID 30085016 DOI: 10.1093/Ecco-Jcc/Jjy105  0.342
2018 Sobral LM, Jedlicka P. Abstract A33: Histone demethylase KDM3A in rhabdomyosarcoma Clinical Cancer Research. 24. DOI: 10.1158/1557-3265.Sarcomas17-A33  0.338
2018 Gumer L, Jedlicka P, Masterson JC, Furuta G, Mack M, McNamee E. Tu1833 - The Micro-RNA MIR-223 Regulates the Inflammatory Tone of CCR2 + Monocytes to Limit Experimental Colitis and Influence Mucosal Healing Gastroenterology. 154: S-1032. DOI: 10.1016/S0016-5085(18)33459-0  0.378
2017 Leinwand KL, Jones AA, Huang RH, Jedlicka P, Kao DJ, de Zoeten EF, Ghosh S, Moaddel R, Wehkamp J, Ostaff MJ, Bader J, Aherne CM, Collins CB. Cannabinoid Receptor-2 Ameliorates Inflammation in Murine Model of Crohn's Disease. Journal of Crohn's & Colitis. PMID 28981653 DOI: 10.1093/Ecco-Jcc/Jjx096  0.34
2017 Moore C, Parrish JK, Jedlicka P. MiR-193b, downregulated in Ewing Sarcoma, targets the ErbB4 oncogene to inhibit anchorage-independent growth. Plos One. 12: e0178028. PMID 28542597 DOI: 10.1371/Journal.Pone.0178028  0.404
2017 Neudecker V, Haneklaus M, Jensen O, Khailova L, Masterson JC, Tye H, Biette K, Jedlicka P, Brodsky KS, Gerich ME, Mack M, Robertson AAB, Cooper MA, Furuta GT, Dinarello CA, et al. Myeloid-derived miR-223 regulates intestinal inflammation via repression of the NLRP3 inflammasome. The Journal of Experimental Medicine. PMID 28487310 DOI: 10.1084/Jem.20160462  0.42
2017 MacManus CF, Collins CB, Nguyen TT, Alfano RW, Jedlicka P, de Zoeten EF. VEN-120, a recombinant human lactoferrin, promotes a regulatory T cell (Treg) phenotype and drives resolution of inflammation in distinct murine models of inflammatory bowel disease. Journal of Crohn's & Colitis. PMID 28472424 DOI: 10.1093/Ecco-Jcc/Jjx056  0.335
2017 Sechler M, Parrish JK, Birks DK, Jedlicka P. The histone demethylase KDM3A, and its downstream target MCAM, promote Ewing Sarcoma cell migration and metastasis. Oncogene. PMID 28319067 DOI: 10.1038/Onc.2017.44  0.379
2016 Spoelstra NS, Cittelly DM, Christenson JL, Gordon MA, Elias A, Jedlicka P, Richer JK. Dicer Expression in Estrogen Receptor Positive versus Triple-Negative Breast Cancer: An Antibody Comparison. Human Pathology. PMID 27260947 DOI: 10.1016/J.Humpath.2016.05.014  0.306
2016 Sechler M, Parrish J, Jedlicka P. Abstract 1635: The histone demethylase KDM3A in Ewing Sarcoma metastasis Cancer Research. 76: 1635-1635. DOI: 10.1158/1538-7445.Am2016-1635  0.372
2015 Aherne CM, Saeedi B, Collins CB, Masterson JC, McNamee EN, Perrenoud L, Rapp CR, Curtis VF, Bayless A, Fletcher A, Glover LE, Evans CM, Jedlicka P, Furuta GT, de Zoeten EF, et al. Epithelial-specific A2B adenosine receptor signaling protects the colonic epithelial barrier during acute colitis. Mucosal Immunology. 8: 1324-38. PMID 25850656 DOI: 10.1038/Mi.2015.22  0.345
2015 Barton VN, D'Amato NC, Gordon MA, Lind HT, Spoelstra NS, Babbs BL, Heinz RE, Elias A, Jedlicka P, Jacobsen BM, Richer JK. Multiple molecular subtypes of triple-negative breast cancer critically rely on androgen receptor and respond to enzalutamide in vivo. Molecular Cancer Therapeutics. 14: 769-78. PMID 25713333 DOI: 10.1158/1535-7163.Mct-14-0926  0.331
2015 McNamee EN, Masterson JC, Veny M, Collins CB, Jedlicka P, Byrne FR, Ng GY, Rivera-Nieves J. Chemokine receptor CCR7 regulates the intestinal TH1/TH17/Treg balance during Crohn's-like murine ileitis. Journal of Leukocyte Biology. 97: 1011-22. PMID 25637591 DOI: 10.1189/Jlb.3Hi0614-303R  0.319
2015 Niemeyer BF, Parrish JK, Spoelstra NS, Joyal T, Richer JK, Jedlicka P. Variable expression of PIK3R3 and PTEN in Ewing Sarcoma impacts oncogenic phenotypes. Plos One. 10: e0116895. PMID 25603314 DOI: 10.1371/Journal.Pone.0116895  0.35
2015 Masterson JC, McNamee EN, Fillon SA, Hosford L, Harris R, Fernando SD, Jedlicka P, Iwamoto R, Jacobsen E, Protheroe C, Eltzschig HK, Colgan SP, Arita M, Lee JJ, Furuta GT. Eosinophil-mediated signalling attenuates inflammatory responses in experimental colitis. Gut. 64: 1236-47. PMID 25209655 DOI: 10.1136/Gutjnl-2014-306998  0.329
2015 Parrish JK, Sechler M, Winn RA, Jedlicka P. The histone demethylase KDM3A is a microRNA-22-regulated tumor promoter in Ewing Sarcoma. Oncogene. 34: 257-62. PMID 24362521 DOI: 10.1038/Onc.2013.541  0.424
2014 Ogba N, Manning NG, Bliesner BS, Ambler SK, Haughian JM, Pinto MP, Jedlicka P, Joensuu K, Heikkilä P, Horwitz KB. Luminal breast cancer metastases and tumor arousal from dormancy are promoted by direct actions of estradiol and progesterone on the malignant cells. Breast Cancer Research : Bcr. 16: 489. PMID 25475897 DOI: 10.1186/S13058-014-0489-4  0.319
2014 Wang CA, Harrell JC, Iwanaga R, Jedlicka P, Ford HL. Vascular endothelial growth factor C promotes breast cancer progression via a novel antioxidant mechanism that involves regulation of superoxide dismutase 3. Breast Cancer Research : Bcr. 16: 462. PMID 25358638 DOI: 10.1186/S13058-014-0462-2  0.302
2014 Wang CA, Drasin D, Pham C, Jedlicka P, Zaberezhnyy V, Guney M, Li H, Nemenoff R, Costello JC, Tan AC, Ford HL. Homeoprotein Six2 promotes breast cancer metastasis via transcriptional and epigenetic control of E-cadherin expression. Cancer Research. 74: 7357-70. PMID 25348955 DOI: 10.1158/0008-5472.Can-14-0666  0.347
2014 Collins CB, Strassheim D, Aherne CM, Yeckes AR, Jedlicka P, de Zoeten EF. Targeted inhibition of heat shock protein 90 suppresses tumor necrosis factor-α and ameliorates murine intestinal inflammation. Inflammatory Bowel Diseases. 20: 685-94. PMID 24552830 DOI: 10.1097/01.Mib.0000442839.28664.75  0.331
2014 Cochrane DR, Bernales S, Jacobsen BM, Cittelly DM, Howe EN, D'Amato NC, Spoelstra NS, Edgerton SM, Jean A, Guerrero J, Gómez F, Medicherla S, Alfaro IE, McCullagh E, Jedlicka P, et al. Role of the androgen receptor in breast cancer and preclinical analysis of enzalutamide. Breast Cancer Research : Bcr. 16: R7. PMID 24451109 DOI: 10.1186/Bcr3599  0.306
2014 Campbell EL, Bruyninckx WJ, Kelly CJ, Glover LE, McNamee EN, Bowers BE, Bayless AJ, Scully M, Saeedi BJ, Golden-Mason L, Ehrentraut SF, Curtis VF, Burgess A, Garvey JF, Sorensen A, ... ... Jedlicka P, et al. Transmigrating neutrophils shape the mucosal microenvironment through localized oxygen depletion to influence resolution of inflammation. Immunity. 40: 66-77. PMID 24412613 DOI: 10.1016/J.Immuni.2013.11.020  0.34
2014 Parrish JK, Sechler M, Jedlicka P. Abstract A75: A new, microRNA-regulated, epigenetic tumor-promoting pathway in Ewing sarcoma Cancer Research. 74. DOI: 10.1158/1538-7445.Pedcan-A75  0.425
2013 Glover LE, Bowers BE, Saeedi B, Ehrentraut SF, Campbell EL, Bayless AJ, Dobrinskikh E, Kendrick AA, Kelly CJ, Burgess A, Miller L, Kominsky DJ, Jedlicka P, Colgan SP. Control of creatine metabolism by HIF is an endogenous mechanism of barrier regulation in colitis. Proceedings of the National Academy of Sciences of the United States of America. 110: 19820-5. PMID 24248342 DOI: 10.1073/Pnas.1302840110  0.339
2013 Collins CB, Aherne CM, Ehrentraut SF, Gerich ME, McNamee EN, McManus MC, Lebsack MD, Jedlicka P, Azam T, de Zoeten EF, Dinarello CA, Rivera-Nieves J. Alpha-1-antitrypsin therapy ameliorates acute colitis and chronic murine ileitis. Inflammatory Bowel Diseases. 19: 1964-73. PMID 23835442 DOI: 10.1097/Mib.0B013E31829292Aa  0.352
2013 Dylla L, Jedlicka P. Growth-promoting role of the miR-106a~363 cluster in Ewing sarcoma. Plos One. 8: e63032. PMID 23638178 DOI: 10.1371/Journal.Pone.0063032  0.689
2013 Dylla L, Moore C, Jedlicka P. MicroRNAs in Ewing Sarcoma. Frontiers in Oncology. 3: 65. PMID 23543617 DOI: 10.3389/Fonc.2013.00065  0.694
2013 Collins CB, Aherne CM, Yeckes A, Pound K, Eltzschig HK, Jedlicka P, de Zoeten EF. Inhibition of N-terminal ATPase on HSP90 attenuates colitis through enhanced Treg function. Mucosal Immunology. 6: 960-71. PMID 23321985 DOI: 10.1038/Mi.2012.134  0.322
2013 Linger RM, Cohen RA, Cummings CT, Sather S, Migdall-Wilson J, Middleton DH, Lu X, Barón AE, Franklin WA, Merrick DT, Jedlicka P, DeRyckere D, Heasley LE, Graham DK. Mer or Axl receptor tyrosine kinase inhibition promotes apoptosis, blocks growth and enhances chemosensitivity of human non-small cell lung cancer. Oncogene. 32: 3420-31. PMID 22890323 DOI: 10.1038/Onc.2012.355  0.352
2013 McNamee EN, Masterson JC, Jedlicka P, Collins CB, Williams IR, Rivera-Nieves J. Ectopic lymphoid tissue alters the chemokine gradient, increases lymphocyte retention and exacerbates murine ileitis. Gut. 62: 53-62. PMID 22267601 DOI: 10.1136/Gutjnl-2011-301272  0.308
2013 Wang C, Jedlicka P, Tan A, Pham C, Zaberezhnvv V, Ford H. Abstract PR04: The Six2 homeoprotein mediates breast cancer metastasis via repressing E-cadherin Molecular Cancer Research. 11. DOI: 10.1158/1557-3125.Advbc-Pr04  0.372
2013 D'Amato NC, Gu H, Cochrane DR, Bernales S, Jacobsen BM, Jedlicka P, Torkko KC, Edgerton SM, Thor AD, Elias AD, Protter AA, Richer JK. Abstract 4756: Elucidating the role of AR in breast cancer . Cancer Research. 73: 4756-4756. DOI: 10.1158/1538-7445.Am2013-4756  0.333
2013 Moore C, Jedlicka P. Abstract 4176: MicroRNA-193b is growth-inhibitory in Ewing sarcoma, and represses ErbB4. Cancer Research. 73: 4176-4176. DOI: 10.1158/1538-7445.Am2013-4176  0.418
2013 Wang C, Jedlicka P, Zaberezhnyy V, Tan A, Ford H. Abstract 2705: Novel functions of the homeoprotein SIX2 in mediating anchorage independence and metastasis in breast cancer. Cancer Research. 73: 2705-2705. DOI: 10.1158/1538-7445.Am2013-2705  0.374
2012 Clambey ET, McNamee EN, Westrich JA, Glover LE, Campbell EL, Jedlicka P, de Zoeten EF, Cambier JC, Stenmark KR, Colgan SP, Eltzschig HK. Hypoxia-inducible factor-1 alpha-dependent induction of FoxP3 drives regulatory T-cell abundance and function during inflammatory hypoxia of the mucosa. Proceedings of the National Academy of Sciences of the United States of America. 109: E2784-93. PMID 22988108 DOI: 10.1073/Pnas.1202366109  0.342
2012 Iwanaga R, Wang CA, Micalizzi DS, Harrell JC, Jedlicka P, Sartorius CA, Kabos P, Farabaugh SM, Bradford AP, Ford HL. Expression of Six1 in luminal breast cancers predicts poor prognosis and promotes increases in tumor initiating cells by activation of extracellular signal-regulated kinase and transforming growth factor-beta signaling pathways. Breast Cancer Research : Bcr. 14: R100. PMID 22765220 DOI: 10.1186/Bcr3219  0.363
2012 Robin TP, Smith A, McKinsey E, Reaves L, Jedlicka P, Ford HL. EWS/FLI1 regulates EYA3 in Ewing sarcoma via modulation of miRNA-708, resulting in increased cell survival and chemoresistance. Molecular Cancer Research : McR. 10: 1098-108. PMID 22723308 DOI: 10.1158/1541-7786.Mcr-12-0086  0.419
2012 Kern HB, Niemeyer BF, Parrish JK, Kerr CA, Yaghi NK, Prescott JD, Gutierrez-Hartmann A, Jedlicka P. Control of MicroRNA-21 expression in colorectal cancer cells by oncogenic epidermal growth factor/Ras signaling and Ets transcription factors. Dna and Cell Biology. 31: 1403-11. PMID 22553926 DOI: 10.1089/Dna.2011.1469  0.422
2012 Wang CA, Jedlicka P, Patrick AN, Micalizzi DS, Lemmer KC, Deitsch E, Casás-Selves M, Harrell JC, Ford HL. SIX1 induces lymphangiogenesis and metastasis via upregulation of VEGF-C in mouse models of breast cancer. The Journal of Clinical Investigation. 122: 1895-906. PMID 22466647 DOI: 10.1172/Jci59858  0.334
2012 Farabaugh SM, Micalizzi DS, Jedlicka P, Zhao R, Ford HL. Eya2 is required to mediate the pro-metastatic functions of Six1 via the induction of TGF-β signaling, epithelial-mesenchymal transition, and cancer stem cell properties. Oncogene. 31: 552-62. PMID 21706047 DOI: 10.1038/Onc.2011.259  0.375
2011 Masterson JC, McNamee EN, Jedlicka P, Fillon S, Ruybal J, Hosford L, Rivera-Nieves J, Lee JJ, Furuta GT. CCR3 Blockade Attenuates Eosinophilic Ileitis and Associated Remodeling. The American Journal of Pathology. 179: 2302-14. PMID 21945903 DOI: 10.1016/J.Ajpath.2011.07.039  0.351
2011 McKinsey EL, Parrish JK, Irwin AE, Niemeyer BF, Kern HB, Birks DK, Jedlicka P. A novel oncogenic mechanism in Ewing sarcoma involving IGF pathway targeting by EWS/Fli1-regulated microRNAs. Oncogene. 30: 4910-20. PMID 21643012 DOI: 10.1038/Onc.2011.197  0.431
2011 Múnera J, Ceceña G, Jedlicka P, Wankell M, Oshima RG. Ets2 regulates colonic stem cells and sensitivity to tumorigenesis. Stem Cells (Dayton, Ohio). 29: 430-9. PMID 21425406 DOI: 10.1002/Stem.599  0.352
2011 Wermers JD, McNamee EN, Wurbel MA, Jedlicka P, Rivera-Nieves J. The chemokine receptor CCR9 is required for the T-cell-mediated regulation of chronic ileitis in mice. Gastroenterology. 140: 1526-35.e3. PMID 21300065 DOI: 10.1053/J.Gastro.2011.01.044  0.33
2011 Wang C, Jedlicka P, Christensen KL, Micalizzi DS, Harrell JC, Ford HL. Abstract 1463: SIX1 induces lymphatic and distant metastasis by upregulating VEGF-C and stimulating lymphangiogenesis in breast cancer Cancer Research. 71: 1463-1463. DOI: 10.1158/1538-7445.Am2011-1463  0.325
2011 Robin TP, Kreuger A, McKinsey E, Reaves L, Jedlicka P, Zhao R, Ford HL. Abstract B78: A novel EWS/Fli1 target gene, Eya3, is upregulated in Ewing's sarcoma to mediate chemoresistance. Molecular Cancer Therapeutics. 10. DOI: 10.1158/1535-7163.Targ-11-B78  0.396
2009 Micalizzi DS, Christensen KL, Jedlicka P, Coletta RD, Barón AE, Harrell JC, Horwitz KB, Billheimer D, Heichman KA, Welm AL, Schiemann WP, Ford HL. The Six1 homeoprotein induces human mammary carcinoma cells to undergo epithelial-mesenchymal transition and metastasis in mice through increasing TGF-beta signaling. The Journal of Clinical Investigation. 119: 2678-90. PMID 19726885 DOI: 10.1172/Jci37815  0.318
2009 McCoy EL, Iwanaga R, Jedlicka P, Abbey NS, Chodosh LA, Heichman KA, Welm AL, Ford HL. Six1 expands the mouse mammary epithelial stem/progenitor cell pool and induces mammary tumors that undergo epithelial-mesenchymal transition. The Journal of Clinical Investigation. 119: 2663-77. PMID 19726883 DOI: 10.1172/Jci37691  0.358
2009 Jedlicka P, Sui X, Gutierrez-Hartmann A. The Ets dominant repressor En/Erm enhances intestinal epithelial tumorigenesis in ApcMin mice. Bmc Cancer. 9: 197. PMID 19545444 DOI: 10.1186/1471-2407-9-197  0.309
2009 Jedlicka P, Sui X, Sussel L, Gutierrez-Hartmann A. Ets transcription factors control epithelial maturation and transit and crypt-villus morphogenesis in the mammalian intestine. The American Journal of Pathology. 174: 1280-90. PMID 19264912 DOI: 10.2353/Ajpath.2009.080409  0.342
2008 Jedlicka P, Gutierrez-Hartmann A. Ets transcription factors in intestinal morphogenesis, homeostasis and disease. Histology and Histopathology. 23: 1417-24. PMID 18785124 DOI: 10.14670/Hh-23.1417  0.332
2008 Coletta RD, Christensen KL, Micalizzi DS, Jedlicka P, Varella-Garcia M, Ford HL. Six1 overexpression in mammary cells induces genomic instability and is sufficient for malignant transformation. Cancer Research. 68: 2204-13. PMID 18381426 DOI: 10.1158/0008-5472.Can-07-3141  0.374
2007 Harrell JC, Dye WW, Harvell DM, Pinto M, Jedlicka P, Sartorius CA, Horwitz KB. Estrogen insensitivity in a model of estrogen receptor positive breast cancer lymph node metastasis. Cancer Research. 67: 10582-91. PMID 17975003 DOI: 10.1158/0008-5472.Can-07-1655  0.336
2006 Harrell JC, Dye WW, Allred DC, Jedlicka P, Spoelstra NS, Sartorius CA, Horwitz KB. Estrogen receptor positive breast cancer metastasis: altered hormonal sensitivity and tumor aggressiveness in lymphatic vessels and lymph nodes. Cancer Research. 66: 9308-15. PMID 16982776 DOI: 10.1158/0008-5472.Can-06-1769  0.338
2006 Jacobsen BM, Harrell JC, Jedlicka P, Borges VF, Varella-Garcia M, Horwitz KB. Spontaneous fusion with, and transformation of mouse stroma by, malignant human breast cancer epithelium. Cancer Research. 66: 8274-9. PMID 16912208 DOI: 10.1158/0008-5472.Can-06-1456  0.321
2004 Coletta RD, Jedlicka P, Gutierrez-Hartmann A, Ford HL. Transcriptional control of the cell cycle in mammary gland development and tumorigenesis. Journal of Mammary Gland Biology and Neoplasia. 9: 39-53. PMID 15082917 DOI: 10.1023/B:Jomg.0000023587.40966.F6  0.334
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