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Angela Casini - Publications

Affiliations: 
School of Chemistry, Minneapolis, MN, United States 
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Year Citation  Score
2024 Casini A, Pöthig A. Metals in Cancer Research: Beyond Platinum Metallodrugs. Acs Central Science. 10: 242-250. PMID 38435529 DOI: 10.1021/acscentsci.3c01340  0.316
2023 Park M, Schmidt C, Türck S, Hanusch F, Hirmer SV, Ott I, Casini A, Inoue S. Potent Anticancer Activity of a Dinuclear Gold(I) Bis-N-Heterocyclic Imine Complex Related to Thioredoxin Reductase Inhibition in Vitro. Chempluschem. e202300557. PMID 37937471 DOI: 10.1002/cplu.202300557  0.319
2023 Deiser S, Drexler M, Moreno-Alcántar G, Irl M, Schmidt C, Günther T, Casini A. Synthesis of Lu-Labeled, Somatostatin-2 Receptor-Targeted Metalla-Assemblies: Challenges in the Design of Supramolecular Radiotherapeutics. Inorganic Chemistry. PMID 37556427 DOI: 10.1021/acs.inorgchem.3c02090  0.78
2023 Scalcon V, Bonsignore R, Aupič J, Thomas SR, Folda A, Heidecker AA, Pöthig A, Magistrato A, Casini A, Rigobello MP. Exploring the Anticancer Activity of Tamoxifen-Based Metal Complexes Targeting Mitochondria. Journal of Medicinal Chemistry. PMID 37410388 DOI: 10.1021/acs.jmedchem.3c00617  0.322
2023 Kumar NM, Gruhs P, Casini A, Biedermann F, Moreno-Alcántar G, Picchetti P. Electrochemical Detection of Drugs via a Supramolecular Cucurbit[7]uril-Based Indicator Displacement Assay. Acs Sensors. PMID 37339775 DOI: 10.1021/acssensors.3c00008  0.771
2023 Moreno-Alcántar G, Picchetti P, Casini A. Gold Complexes in Anticancer Therapy: From New Design Principles to Particle-Based Delivery Systems. Angewandte Chemie (International Ed. in English). e202218000. PMID 36847211 DOI: 10.1002/anie.202218000  0.791
2022 Kaußler C, Wragg D, Schmidt C, Moreno-Alcántar G, Jandl C, Stephan J, Fischer RA, Leoni S, Casini A, Bonsignore R. "Dynamical Docking" of Cyclic Dinuclear Au(I) Bis-N-heterocyclic Complexes Facilitates Their Binding to G-Quadruplexes. Inorganic Chemistry. PMID 36484812 DOI: 10.1021/acs.inorgchem.2c03041  0.798
2022 Moreno-Alcántar G, Casini A. Bioinorganic Supramolecular Coordination Complexes and Their Biomedical Applications. Febs Letters. PMID 36345593 DOI: 10.1002/1873-3468.14535  0.778
2022 Schmidt C, Zollo M, Bonsignore R, Casini A, Hacker SM. Competitive profiling of ligandable cysteines in with an organogold compound. Chemical Communications (Cambridge, England). 58: 5526-5529. PMID 35420608 DOI: 10.1039/d2cc01259f  0.326
2020 Meier-Menches S, Neuditschko B, Zappe K, Schaier M, Gerner M, Schmetterer K, Del Favero G, Bonsignore R, Cichna-Makl M, Koellensperger G, Casini A, Gerner C. An organometallic gold(I) bis-N-heterocyclic carbene complex with multimodal activity in ovarian cancer cells. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 32902006 DOI: 10.1002/Chem.202003495  0.42
2020 Minori K, Rosa LB, Bonsignore R, Casini A, Miguel DC. Comparing the antileishmanial activity of gold(I) and gold(III) compounds in L. amazonensis and L. braziliensisin vitro. Chemmedchem. PMID 32830445 DOI: 10.1002/Cmdc.202000536  0.355
2020 Kaur G, Javed W, Ponomarenko O, Shekh K, Swanlund DP, Zhou JR, Summers KL, Casini A, Wenzel M, Casey JR, Cordat E, Pickering IJ, George GN, Leslie EM. Human Red Blood Cell Uptake and Sequestration of Arsenite and Selenite: Evidence of Seleno-bis(S-glutathionyl) Arsinium Ion Formation in Human Cells. Biochemical Pharmacology. 114141. PMID 32652143 DOI: 10.1016/J.Bcp.2020.114141  0.317
2020 Thomas SR, Bonsignore R, Escudero Sanchez J, Meier-Menches SM, Brown C, Wolf M, Barone G, Luk LY, Casini A. Exploring the chemoselectivity towards cysteine arylation by cyclometalated Au(III) compounds: new mechanistic insights. Chembiochem : a European Journal of Chemical Biology. PMID 32511840 DOI: 10.1002/Cbic.202000262  0.366
2020 Han J, Sun J, Song S, Beljaars L, Groothuis GMM, Permentier H, Bischoff R, Halmos GB, Verhoeven CJ, Amstalden van Hove ER, Horvatovich P, Casini A. Targeted imaging of integrins in cancer tissues using photocleavable Ru(ii) polypyridine complexes as mass-tags. Chemical Communications (Cambridge, England). PMID 32347235 DOI: 10.1039/D0Cc00774A  0.308
2020 Thomas SR, Casini A. Gold compounds for catalysis and metal-mediated transformations in biological systems. Current Opinion in Chemical Biology. 55: 103-110. PMID 32086166 DOI: 10.1016/J.Cbpa.2019.12.007  0.351
2020 Daga M, de Graaf IAM, Argenziano M, Barranco ASM, Loeck M, Mohammed Y, Cucci MA, Caldera F, Trotta F, Barrera G, Casini A, Cavalli R, Pizzimenti S. Glutathione-responsive cyclodextrin-nanosponges as drug delivery systems for doxorubicin: Evaluation of toxicity and transport mechanisms in the liver. Toxicology in Vitro : An International Journal Published in Association With Bibra. 104800. PMID 32084521 DOI: 10.1016/J.Tiv.2020.104800  0.308
2020 Bonsignore R, Thomas S, Klooster W, Coles S, Bourissou D, Jenkins R, Barone G, Casini A. Carbon-Phosphorus Coupling from C^N Cyclometalated Au(III) Complexes. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 31994237 DOI: 10.1002/Chem.201905392  0.354
2020 Oberkofler J, Aikman B, Bonsignore R, Pöthig A, Platts J, Casini A, Kühn FE. Exploring the Reactivity and Biological Effects of Heteroleptic N-Heterocyclic Carbene Gold(I)-Alkynyl Complexes European Journal of Inorganic Chemistry. 2020: 1040-1051. DOI: 10.1002/Ejic.201901043  0.422
2019 Estrada-Ortiz N, Lopez-Gonzales E, Woods B, Stürup S, de Graaf IAM, Groothuis GMM, Casini A. toxicological evaluation of experimental anticancer gold(i) complexes with lansoprazole-type ligands. Toxicology Research. 8: 885-895. PMID 32190293 DOI: 10.1039/C9Tx00149B  0.469
2019 Meier-Menches SM, Aikman B, Döllerer D, Klooster WT, Coles SJ, Santi N, Luk L, Casini A, Bonsignore R. Comparative biological evaluation and G-quadruplex interaction studies of two new families of organometallic gold(I) complexes featuring N-heterocyclic carbene and alkynyl ligands. Journal of Inorganic Biochemistry. 202: 110844. PMID 31739113 DOI: 10.1016/J.Jinorgbio.2019.110844  0.434
2019 Woods B, Döllerer D, Aikman B, Wenzel MN, Sayers EJ, Kühn FE, Jones AT, Casini A. Highly luminescent metallacages featuring bispyridyl ligands functionalised with BODIPY for imaging in cancer cells. Journal of Inorganic Biochemistry. 199: 110781. PMID 31357067 DOI: 10.1016/J.Jinorgbio.2019.110781  0.37
2019 Pöthig A, Casini A. Recent Developments of Supramolecular Metal-based Structures for Applications in Cancer Therapy and Imaging. Theranostics. 9: 3150-3169. PMID 31244947 DOI: 10.7150/Thno.31828  0.383
2019 Wragg D, de Almeida A, Casini A, Leoni S. Unveiling the mechanisms of aquaglyceroporin-3 water and glycerol permeation by metadynamics. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 31081563 DOI: 10.1002/Chem.201902121  0.712
2019 Mazzei L, Wenzel MN, Cianci M, Palombo M, Casini A, Ciurli S. Inhibition Mechanism of Urease by Au(III) Compounds Unveiled by X-ray Diffraction Analysis. Acs Medicinal Chemistry Letters. 10: 564-570. PMID 30996797 DOI: 10.1021/Acsmedchemlett.8B00585  0.431
2019 Wenzel M, Bonsignore R, Thomas S, Bourissou D, Barone G, Casini A. Cyclometalated Au(III) Complexes for Cysteine Arylation in Zinc Finger Protein Domains: Towards Controlled Reductive Elimination. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 30990916 DOI: 10.1002/Chem.201901535  0.425
2019 Pinho JO, Amaral JD, Castro RE, Rodrigues CM, Casini A, Soveral G, Gaspar MM. Copper complex nanoformulations featuring highly promising therapeutic potential in murine melanoma models. Nanomedicine (London, England). PMID 30875274 DOI: 10.2217/Nnm-2018-0388  0.337
2019 Woods B, Wenzel MN, Williams T, Thomas SR, Jenkins RL, Casini A. -Functionalized Metallacages as Host-Guest Systems for the Anticancer Drug Cisplatin. Frontiers in Chemistry. 7: 68. PMID 30834242 DOI: 10.3389/Fchem.2019.00068  0.371
2019 Wenzel MN, Mósca AF, Graziani V, Aikman B, Thomas SR, de Almeida A, Platts JA, Re N, Coletti C, Marrone A, Soveral G, Casini A. Insights into the Mechanisms of Aquaporin-3 Inhibition by Gold(III) Complexes: the Importance of Non-Coordinative Adduct Formation. Inorganic Chemistry. PMID 30645101 DOI: 10.1021/Acs.Inorgchem.8B03233  0.8
2018 Carboni S, Zucca A, Stoccoro S, Maiore L, Arca M, Ortu F, Artner C, Keppler BK, Meier-Menches SM, Casini A, Cinellu MA. New Variations on the Theme of Gold(III) CNN Cyclometalated Complexes as Anticancer Agents: Synthesis and Biological Characterization. Inorganic Chemistry. PMID 30457328 DOI: 10.1021/Acs.Inorgchem.8B02604  0.471
2018 Mósca AF, de Almeida A, Wragg D, Martins AP, Sabir F, Leoni S, Moura TF, Prista C, Casini A, Soveral G. Molecular Basis of Aquaporin-7 Permeability Regulation by pH. Cells. 7. PMID 30423801 DOI: 10.3390/Cells7110207  0.718
2018 Han J, Rader A, Reichart F, Aikman B, Wenzel MN, Woods B, Weinmüller M, Ludwig BS, Sturup S, Groothuis GMM, Permentier HP, Bischoff R, Kessler H, Horvatovich P, Casini A. Bioconjugation of Supramolecular Metallacages to Integrin Ligands for Targeted Delivery of Cisplatin. Bioconjugate Chemistry. PMID 30380298 DOI: 10.1021/Acs.Bioconjchem.8B00682  0.372
2018 Spreckelmeyer S, van der Zee M, Bertrand B, Bodio E, Stürup S, Casini A. Relevance of Copper and Organic Cation Transporters in the Activity and Transport Mechanisms of an Anticancer Cyclometallated Gold(III) Compound in Comparison to Cisplatin. Frontiers in Chemistry. 6: 377. PMID 30234099 DOI: 10.3389/Fchem.2018.00377  0.41
2018 Wragg D, de Almeida A, Bonsignore R, Kuehn F, Leoni S, Casini A. On the mechanism of gold NHC compounds binding to DNA G- quadruplexes elucidated by combined metadynamics and biophysical methods. Angewandte Chemie (International Ed. in English). PMID 29972613 DOI: 10.1002/Anie.201805727  0.751
2018 Aikman B, de Almeida A, Meier-Menches SM, Casini A. Aquaporins in cancer development: opportunities for bioinorganic chemistry to contribute novel chemical probes and therapeutic agents. Metallomics : Integrated Biometal Science. PMID 29766198 DOI: 10.1039/C8Mt00072G  0.761
2018 Boscutti G, Nardon C, Marchiò L, Crisma M, Biondi B, Dalzoppo D, Dalla Via L, Formaggio F, Casini A, Fregona D. Anticancer gold(III) peptidomimetics: from synthesis to in vitro and ex vivo biological evaluation. Chemmedchem. PMID 29570944 DOI: 10.1002/Cmdc.201800098  0.404
2018 Casini A, Sun RW, Ott I. Medicinal Chemistry of Gold Anticancer Metallodrugs. Metal Ions in Life Sciences. 18. PMID 29394026 DOI: 10.1515/9783110470734-013  0.351
2018 Wenzel MN, Meier-Menches SM, Williams TL, Rämisch E, Barone G, Casini A. Selective targeting of PARP-1 zinc finger recognition domains with Au(iii) organometallics. Chemical Communications (Cambridge, England). PMID 29292454 DOI: 10.1039/C7Cc08406D  0.401
2017 Casini A, Woods B, Wenzel M. The Promise of Self-Assembled 3D Supramolecular Coordination Complexes for Biomedical Applications. Inorganic Chemistry. 56: 14715-14729. PMID 29172467 DOI: 10.1021/Acs.Inorgchem.7B02599  0.34
2017 Spreckelmeyer S, Estrada-Ortiz N, Prins GGH, van der Zee M, Gammelgaard B, Stürup S, de Graaf IAM, Groothuis GMM, Casini A. On the toxicity and transport mechanisms of cisplatin in kidney tissues in comparison to a gold-based cytotoxic agent. Metallomics : Integrated Biometal Science. PMID 29104982 DOI: 10.1039/C7Mt00271H  0.386
2017 Karaca Ö, Scalcon V, Meier-Menches SM, Bonsignore R, Brouwer JMJL, Tonolo F, Folda A, Rigobello MP, Kühn FE, Casini A. Characterization of Hydrophilic Gold(I) N-Heterocyclic Carbene (NHC) Complexes as Potent TrxR Inhibitors Using Biochemical and Mass Spectrometric Approaches. Inorganic Chemistry. PMID 29095609 DOI: 10.1021/Acs.Inorgchem.7B02345  0.511
2017 Boorsma CE, van der Veen TA, Putri KSS, de Almeida A, Draijer C, Mauad T, Fejer G, Brandsma CA, van den Berge M, Bossé Y, Sin D, Hao K, Reithmeier A, Andersson G, Olinga P, ... ... Casini A, et al. A Potent Tartrate Resistant Acid Phosphatase Inhibitor to Study the Function of TRAP in Alveolar Macrophages. Scientific Reports. 7: 12570. PMID 28974738 DOI: 10.1038/S41598-017-12623-W  0.719
2017 Jürgens S, Scalcon V, Estrada-Ortiz N, Folda A, Tonolo F, Jandl C, Browne DL, Rigobello MP, Kühn FE, Casini A. Exploring the C^N^C theme: Synthesis and biological properties of tridentate cyclometalated gold(III) complexes. Bioorganic & Medicinal Chemistry. PMID 28823538 DOI: 10.1016/J.Bmc.2017.08.001  0.398
2017 Graziani V, Marrone A, Re N, Coletti C, Platts JA, Casini A. A multilevel theoretical study to disclose the binding mechanisms of gold(III) bipyridyl compounds as selective aquaglyceroporin inhibitors. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 28776779 DOI: 10.1002/Chem.201703092  0.44
2017 Casini A, Estrada-Ortiz N, Gabbiani C, Guarra F, Groothuis G, de Graaf I, de Jager M, Marchetti L. Anticancer gold N-heterocyclic carbene complexes: a comparative in vitro and ex vivo study. Chemmedchem. PMID 28741878 DOI: 10.1002/Cmdc.201700316  0.443
2017 Karaca Ö, Meier-Menches SM, Casini A, Kühn FE. On the binding modes of metal NHC complexes with DNA secondary structures: implications for therapy and imaging. Chemical Communications (Cambridge, England). PMID 28653066 DOI: 10.1039/C7Cc03074F  0.397
2017 Jürgens S, Casini A. Mechanistic Insights into Gold Organometallic Compounds and their Biomedical Applications. Chimia. 71: 308. PMID 28576158 DOI: 10.2533/Chimia.2017.308  0.363
2017 Jürgens S, Kühn FE, Casini A. Cyclometalated complexes of platinum and gold with biological properties: state-of-the-art and future perspectives. Current Medicinal Chemistry. PMID 28554319 DOI: 10.2174/0929867324666170529125229  0.441
2017 Jürgens S, Casini A. Mechanistic Insights into Gold Organometallic Compounds and their Biomedical Applications. Chimia. 71: 92-101. PMID 28351454 DOI: 10.2533/Chimia.2017.92  0.425
2017 de Almeida A, Mósca AF, Wragg D, Wenzel M, Kavanagh P, Barone G, Leoni S, Soveral G, Casini A. The mechanism of aquaporin inhibition by gold compounds elucidated by biophysical and computational methods. Chemical Communications (Cambridge, England). PMID 28304043 DOI: 10.1039/C7Cc00318H  0.77
2017 Wenzel M, Casini A. Mass spectrometry as a powerful tool to study therapeutic metallodrugs speciation mechanisms: Current frontiers and perspectives Coordination Chemistry Reviews. 352: 432-460. DOI: 10.1016/J.Ccr.2017.02.012  0.403
2017 Medrano MA, Morais M, Ferreira VFC, Correia JDG, Paulo A, Santos I, Navarro-Ranninger C, Valdes AA, Casini A, Mendes F, Quiroga AG. Nonconventionaltrans-Platinum Complexes Functionalized with RDG Peptides: Chemical and Cytototoxicity Studies European Journal of Inorganic Chemistry. 2017: 1835-1840. DOI: 10.1002/Ejic.201700072  0.338
2016 Muenzner JK, Biersack B, Albrecht A, Rehm T, Lacher U, Milius W, Casini A, Zhang JJ, Ott I, Brabec V, Stuchlikova O, Andronache IC, Schuppan D, Kaps L, Schobert R. Ferrocenyl-Coupled N-Heterocyclic Carbene Complexes of Gold(I): a Successful Approach to Multinuclear Anticancer Drugs. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 27761940 DOI: 10.1002/Chem.201604246  0.389
2016 Khan RA, de Almeida A, Al-Farhan K, Alsalme A, Casini A, Ghazzali M, Reedijk J. Transition-metal norharmane compounds as possible cytotoxic agents: New insights based on a coordination chemistry perspective. Journal of Inorganic Biochemistry. PMID 27453532 DOI: 10.1016/J.Jinorgbio.2016.07.001  0.77
2016 Schmidt A, Hollering M, Han J, Casini A, Kühn FE. Self-assembly of highly luminescent heteronuclear coordination cages. Dalton Transactions (Cambridge, England : 2003). PMID 27436541 DOI: 10.1039/C6Dt02708C  0.364
2016 Nave M, Castro RE, Rodrigues CM, Casini A, Soveral G, Gaspar MM. Nanoformulations of a potent copper-based aquaporin inhibitor with cytotoxic effect against cancer cells. Nanomedicine (London, England). 11: 1817-30. PMID 27388811 DOI: 10.2217/Nnm-2016-0086  0.314
2016 Gabbiani C, Pratesi A, Marchetti L, Casini A, Leoni P, Pillozzi S, Crociani O, Bartoli G, Messori L. Potent in vitro antiproliferative properties for a triplatinum cluster toward triple negative breast cancer cells. Journal of Inorganic Biochemistry. PMID 27381671 DOI: 10.1016/J.Jinorgbio.2016.06.024  0.561
2016 Schmidt A, Hollering M, Drees M, Casini A, Kühn FE. Supramolecular exo-functionalized palladium cages: fluorescent properties and biological activity. Dalton Transactions (Cambridge, England : 2003). PMID 27126799 DOI: 10.1039/C6Dt00654J  0.352
2016 de Almeida A, Martins AP, Mósca AF, Wijma HJ, Prista C, Soveral G, Casini A. Exploring the gating mechanisms of aquaporin-3: new clues for the design of inhibitors? Molecular Biosystems. 12: 1564-73. PMID 26960817 DOI: 10.1039/C6Mb00013D  0.732
2016 Bazzicalupi C, Ferraroni M, Papi F, Massai L, Bertrand B, Messori L, Gratteri P, Casini A. Determinants for Tight and Selective Binding of a Medicinal Dicarbene Gold(I) Complex to a Telomeric DNA G-Quadruplex: a Joint ESI MS and XRD Investigation. Angewandte Chemie (International Ed. in English). PMID 26929051 DOI: 10.1002/Anie.201511999  0.583
2016 Wenzel M, de Almeida A, Bigaeva E, Kavanagh P, Picquet M, Le Gendre P, Bodio E, Casini A. New Luminescent Polynuclear Metal Complexes with Anticancer Properties: Toward Structure-Activity Relationships. Inorganic Chemistry. PMID 26867101 DOI: 10.1021/Acs.Inorgchem.5B02910  0.783
2016 Meier SM, Gerner C, Keppler BK, Cinellu MA, Casini A. Mass Spectrometry Uncovers Molecular Reactivities of Coordination and Organometallic Gold(III) Drug Candidates in Competitive Experiments That Correlate with Their Biological Effects. Inorganic Chemistry. 55: 4248-59. PMID 26866307 DOI: 10.1021/Acs.Inorgchem.5B03000  0.428
2016 Spinello A, de Almeida A, Casini A, Barone G. The inhibition of glycerol permeation through aquaglyceroporin-3 induced by mercury(II): A molecular dynamics study. Journal of Inorganic Biochemistry. 160: 78-84. PMID 26766001 DOI: 10.1016/J.Jinorgbio.2015.11.027  0.748
2016 Schmidt A, Molano V, Hollering M, Pöthig A, Casini A, Kühn FE. Evaluation of New Palladium Cages as Potential Delivery Systems for the Anticancer Drug Cisplatin. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 26756963 DOI: 10.1002/Chem.201504930  0.314
2016 Citta A, Scalcon V, Göbel P, Bertrand B, Wenzel M, Folda A, Rigobello MP, Meggers E, Casini A. Toward anticancer gold-based compounds targeting PARP-1: a new case study Rsc Advances. 6: 79147-79152. DOI: 10.1039/C6Ra11606J  0.483
2016 Tsitsa I, Tarushi A, Doukoume P, Perdih F, de Almeida A, Papadopoulos A, Kalogiannis S, Casini A, Turel I, Psomas G. Structure and biological activities of metal complexes of flumequine Rsc Advances. 6: 19555-19570. DOI: 10.1039/C5Ra25776J  0.391
2016 Hahn EM, Estrada-Ortiz N, Han J, Ferreira VFC, Kapp TG, Correia JDG, Casini A, Kühn FE. Functionalization of Ruthenium(II) Terpyridine Complexes with Cyclic RGD Peptides To Target Integrin Receptors in Cancer Cells European Journal of Inorganic Chemistry. 2017: 1667-1672. DOI: 10.1002/Ejic.201601094  0.374
2016 Kaiser F, Schmidt A, Heydenreuter W, Altmann PJ, Casini A, Sieber SA, Kühn FE. Self-Assembled Palladium and Platinum Coordination Cages: Photophysical Studies and Anticancer Activity European Journal of Inorganic Chemistry. 2016: 5189-5196. DOI: 10.1002/Ejic.201600811  0.368
2015 Folda A, Scalcon V, Ghazzali M, Jaafar MH, Khan RA, Casini A, Citta A, Bindoli A, Rigobello MP, Al-Farhan K, Alsalme A, Reedijk J. Insights into the strong in-vitro anticancer effects for bis(triphenylphosphane)iminium compounds having perchlorate, tetrafluoridoborate and bis(chlorido)argentate anions. Journal of Inorganic Biochemistry. PMID 26384162 DOI: 10.1016/J.Jinorgbio.2015.08.030  0.439
2015 Rajaratnam R, Martin EK, Dörr M, Harms K, Casini A, Meggers E. Correlation between the Stereochemistry and Bioactivity in Octahedral Rhodium Prolinato Complexes. Inorganic Chemistry. 54: 8111-20. PMID 26251218 DOI: 10.1021/Acs.Inorgchem.5B01349  0.416
2015 Bertrand B, Citta A, Franken IL, Picquet M, Folda A, Scalcon V, Rigobello MP, Le Gendre P, Casini A, Bodio E. Gold(I) NHC-based homo- and heterobimetallic complexes: synthesis, characterization and evaluation as potential anticancer agents. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 20: 1005-20. PMID 26202908 DOI: 10.1007/S00775-015-1283-1  0.467
2015 Muenzner JK, Rehm T, Biersack B, Casini A, de Graaf IA, Worawutputtapong P, Noor A, Kempe R, Brabec V, Kasparkova J, Schobert R. Adjusting the DNA Interaction and Anticancer Activity of Pt(II) N-Heterocyclic Carbene Complexes by Steric Shielding of the Trans Leaving Group. Journal of Medicinal Chemistry. 58: 6283-92. PMID 26182125 DOI: 10.1021/Acs.Jmedchem.5B00896  0.388
2015 Bertrand B, Spreckelmeyer S, Bodio E, Cocco F, Picquet M, Richard P, Le Gendre P, Orvig C, Cinellu MA, Casini A. Exploring the potential of gold(iii) cyclometallated compounds as cytotoxic agents: variations on the C^N theme. Dalton Transactions (Cambridge, England : 2003). 44: 11911-8. PMID 26060937 DOI: 10.1039/C5Dt01023C  0.439
2015 Jacques A, Lebrun C, Casini A, Kieffer I, Proux O, Latour JM, Sénèque O. Reactivity of Cys4 zinc finger domains with gold(III) complexes: Insights into the formation of "gold fingers" Inorganic Chemistry. 54: 4104-4113. PMID 25839236 DOI: 10.1021/Acs.Inorgchem.5B00360  0.428
2015 Laskay ÜA, Garino C, Tsybin YO, Salassa L, Casini A. Gold finger formation studied by high-resolution mass spectrometry and in silico methods. Chemical Communications (Cambridge, England). 51: 1612-5. PMID 25500668 DOI: 10.1039/C4Cc07490D  0.355
2015 Bertrand B, Bodio E, Richard P, Picquet M, Le Gendre P, Casini A. Gold(I) N-heterocyclic carbene complexes with an "activable" ester moiety: Possible biological applications Journal of Organometallic Chemistry. 775: 124-129. DOI: 10.1016/J.Jorganchem.2014.03.020  0.459
2014 Frik M, Jiménez J, Vasilevski V, Carreira M, de Almeida A, Gascón E, Benoit F, Sanaú M, Casini A, Contel M. Luminescent iminophosphorane gold, palladium and platinum complexes as potential anticancer agents. Inorganic Chemistry Frontiers. 1: 231-241. PMID 27660713 DOI: 10.1039/C4Qi00003J  0.784
2014 Spreckelmeyer S, Orvig C, Casini A. Cellular transport mechanisms of cytotoxic metallodrugs: an overview beyond cisplatin. Molecules (Basel, Switzerland). 19: 15584-610. PMID 25268716 DOI: 10.3390/Molecules191015584  0.429
2014 Wenzel M, Bigaeva E, Richard P, Le Gendre P, Picquet M, Casini A, Bodio E. New heteronuclear gold(I)-platinum(II) complexes with cytotoxic properties: are two metals better than one? Journal of Inorganic Biochemistry. 141: 10-6. PMID 25172993 DOI: 10.1016/J.Jinorgbio.2014.07.011  0.494
2014 Ahmad Khan R, Al-Farhan K, de Almeida A, Alsalme A, Casini A, Ghazzali M, Reedijk J. Light-stable bis(norharmane)silver(I) compounds: synthesis, characterization and antiproliferative effects in cancer cells. Journal of Inorganic Biochemistry. 140: 1-5. PMID 25042730 DOI: 10.1016/J.Jinorgbio.2014.06.019  0.769
2014 Madeira A, De Almeida A, De Graaf C, Camps M, Zorzano A, Moura TF, Casini A, Soveral G. A gold coordination compound as a chemical probe to unravel aquaporin-7 function Chembiochem. 15: 1487-1494. PMID 24891084 DOI: 10.1002/Cbic.201402103  0.763
2014 Rubbiani R, Salassa L, de Almeida A, Casini A, Ott I. Cytotoxic gold(I) N-heterocyclic carbene complexes with phosphane ligands as potent enzyme inhibitors. Chemmedchem. 9: 1205-10. PMID 24677779 DOI: 10.1002/Cmdc.201400056  0.78
2014 Serna A, Galán-Cobo A, Rodrigues C, Sánchez-Gomar I, Toledo-Aral JJ, Moura TF, Casini A, Soveral G, Echevarría M. Functional inhibition of aquaporin-3 with a gold-based compound induces blockage of cell proliferation. Journal of Cellular Physiology. 229: 1787-801. PMID 24676973 DOI: 10.1002/Jcp.24632  0.34
2014 De March M, Demitri N, De Zorzi R, Casini A, Gabbiani C, Guerri A, Messori L, Geremia S. Nitrate as a probe of cytochrome c surface: crystallographic identification of crucial "hot spots" for protein-protein recognition. Journal of Inorganic Biochemistry. 135: 58-67. PMID 24662464 DOI: 10.1016/J.Jinorgbio.2014.02.015  0.522
2014 Bertrand B, Stefan L, Pirrotta M, Monchaud D, Bodio E, Richard P, Le Gendre P, Warmerdam E, de Jager MH, Groothuis GM, Picquet M, Casini A. Caffeine-based gold(I) N-heterocyclic carbenes as possible anticancer agents: synthesis and biological properties. Inorganic Chemistry. 53: 2296-303. PMID 24499428 DOI: 10.1021/Ic403011H  0.448
2014 Bertrand B, Casini A. A golden future in medicinal inorganic chemistry: the promise of anticancer gold organometallic compounds. Dalton Transactions (Cambridge, England : 2003). 43: 4209-19. PMID 24225667 DOI: 10.1039/C3Dt52524D  0.469
2014 de Almeida A, Soveral G, Casini A. Gold compounds as aquaporin inhibitors: new opportunities for therapy and imaging Med. Chem. Commun.. 5: 1444-1453. DOI: 10.1039/C4Md00265B  0.368
2014 Serratice M, Bertrand B, Janssen EFJ, Hemelt E, Zucca A, Cocco F, Cinellu MA, Casini A. Gold(i) compounds with lansoprazole-type ligands: synthesis, characterization and anticancer properties in vitro Med. Chem. Commun.. 5: 1418-1422. DOI: 10.1039/C4Md00241E  0.408
2014 Hahn EM, Casini A, Kühn FE. Re(VII) and Tc(VII) trioxo complexes stabilized by tridentate ligands and their potential use as radiopharmaceuticals Coordination Chemistry Reviews. 276: 97-111. DOI: 10.1016/J.Ccr.2014.05.021  0.403
2014 Schmidt A, Casini A, Kühn FE. Self-assembled M2L4 coordination cages: Synthesis and potential applications Coordination Chemistry Reviews. 275: 19-36. DOI: 10.1016/J.Ccr.2014.03.037  0.344
2014 Bertrand B, Almeida Ad, Burgt EPMvd, Picquet M, Citta A, Folda A, Rigobello MP, Gendre PL, Bodio E, Casini A. New Gold(I) Organometallic Compounds with Biological Activity in Cancer Cells (Eur. J. Inorg. Chem. 27/2014) European Journal of Inorganic Chemistry. 2014. DOI: 10.1002/Ejic.201490137  0.371
2014 Bertrand B, Almeida Ad, Burgt EPMvd, Picquet M, Citta A, Folda A, Rigobello MP, Gendre PL, Bodio E, Casini A. New Gold(I) Organometallic Compounds with Biological Activity in Cancer Cells European Journal of Inorganic Chemistry. 2014: 4532-4536. DOI: 10.1002/Ejic.201402248  0.427
2014 Rubbiani R, Salassa L, Almeida Ad, Casini A, Ott I. Cover Picture: Cytotoxic Gold(I) N‐heterocyclic Carbene Complexes with Phosphane Ligands as Potent Enzyme Inhibitors (ChemMedChem 6/2014) Chemmedchem. 9: 1085-1085. DOI: 10.1002/Cmdc.201490020  0.377
2013 Hanif M, Meier SM, Nazarov AA, Risse J, Legin A, Casini A, Jakupec MA, Keppler BK, Hartinger CG. Influence of the π-coordinated arene on the anticancer activity of ruthenium(II) carbohydrate organometallic complexes. Frontiers in Chemistry. 1: 27. PMID 24790955 DOI: 10.3389/Fchem.2013.00027  0.471
2013 Lease N, Vasilevski V, Carreira M, de Almeida A, Sanaú M, Hirva P, Casini A, Contel M. Potential anticancer heterometallic Fe-Au and Fe-Pd agents: initial mechanistic insights. Journal of Medicinal Chemistry. 56: 5806-18. PMID 23786413 DOI: 10.1021/Jm4007615  0.758
2013 Citta A, Schuh E, Mohr F, Folda A, Massimino ML, Bindoli A, Casini A, Rigobello MP. Fluorescent silver(I) and gold(I)-N-heterocyclic carbene complexes with cytotoxic properties: mechanistic insights. Metallomics : Integrated Biometal Science. 5: 1006-15. PMID 23661165 DOI: 10.1039/C3Mt20260G  0.392
2013 Hartinger CG, Groessl M, Meier SM, Casini A, Dyson PJ. Application of mass spectrometric techniques to delineate the modes-of-action of anticancer metallodrugs. Chemical Society Reviews. 42: 6186-99. PMID 23660626 DOI: 10.1039/C3Cs35532B  0.366
2013 Martins AP, Ciancetta A, deAlmeida A, Marrone A, Re N, Soveral G, Casini A. Aquaporin inhibition by gold(III) compounds: New insights Chemmedchem. 8: 1086-1092. PMID 23653381 DOI: 10.1002/Cmdc.201300107  0.445
2013 Tasan S, Zava O, Bertrand B, Bernhard C, Goze C, Picquet M, Le Gendre P, Harvey P, Denat F, Casini A, Bodio E. BODIPY-phosphane as a versatile tool for easy access to new metal-based theranostics. Dalton Transactions (Cambridge, England : 2003). 42: 6102-9. PMID 23232925 DOI: 10.1039/C2Dt32055J  0.395
2013 De Luca A, Hartinger CG, Dyson PJ, Lo Bello M, Casini A. A new target for gold(I) compounds: glutathione-S-transferase inhibition by auranofin. Journal of Inorganic Biochemistry. 119: 38-42. PMID 23183361 DOI: 10.1016/J.Jinorgbio.2012.08.006  0.433
2013 Guidi F, Modesti A, Landini I, Nobili S, Mini E, Bini L, Puglia M, Casini A, Dyson PJ, Gabbiani C, Messori L. The molecular mechanisms of antimetastatic ruthenium compounds explored through DIGE proteomics. Journal of Inorganic Biochemistry. 118: 94-9. PMID 23142974 DOI: 10.1016/J.Jinorgbio.2012.10.003  0.565
2013 de Almeida A, Oliveira BL, Correia JD, Soveral G, Casini A. Emerging protein targets for metal-based pharmaceutical agents: An update Coordination Chemistry Reviews. 257: 2689-2704. DOI: 10.1016/J.Ccr.2013.01.031  0.411
2012 Martins AP, Marrone A, Ciancetta A, Galán Cobo A, Echevarría M, Moura TF, Re N, Casini A, Soveral G. Targeting aquaporin function: potent inhibition of aquaglyceroporin-3 by a gold-based compound. Plos One. 7: e37435. PMID 22624030 DOI: 10.1371/Journal.Pone.0037435  0.47
2012 Schuh E, Pflüger C, Citta A, Folda A, Rigobello MP, Bindoli A, Casini A, Mohr F. Gold(I) carbene complexes causing thioredoxin 1 and thioredoxin 2 oxidation as potential anticancer agents. Journal of Medicinal Chemistry. 55: 5518-28. PMID 22621714 DOI: 10.1021/Jm300428V  0.449
2012 Casini A. Exploring the mechanisms of metal-based pharmacological agents via an integrated approach. Journal of Inorganic Biochemistry. 109: 97-106. PMID 22342074 DOI: 10.1016/J.Jinorgbio.2011.12.007  0.38
2012 Serratrice M, Edafe F, Mendes F, Scopelliti R, Zakeeruddin SM, Grätzel M, Santos I, Cinellu MA, Casini A. Cytotoxic gold compounds: synthesis, biological characterization and investigation of their inhibition properties of the zinc finger protein PARP-1. Dalton Transactions (Cambridge, England : 2003). 41: 3287-93. PMID 22289927 DOI: 10.1039/C2Dt11913G  0.49
2012 Komeda S, Casini A. Next-generation anticancer metallodrugs. Current Topics in Medicinal Chemistry. 12: 219-35. PMID 22236158 DOI: 10.2174/156802612799078964  0.436
2012 Messori L, Cubo L, Gabbiani C, Álvarez-Valdés A, Michelucci E, Pieraccini G, Ríos-Luci C, León LG, Padrón JM, Navarro-Ranninger C, Casini A, Quiroga AG. Reactivity and biological properties of a series of cytotoxic PtI2(amine)2 complexes, either cis or trans configured. Inorganic Chemistry. 51: 1717-26. PMID 22225466 DOI: 10.1021/Ic202036C  0.603
2012 Casini A, Reedijk J. Interactions of anticancer Pt compounds with proteins: An overlooked topic in medicinal inorganic chemistry? Chemical Science. 3: 3135-3144. DOI: 10.1039/C2Sc20627G  0.416
2011 Stepanenko IN, Casini A, Edafe F, Novak MS, Arion VB, Dyson PJ, Jakupec MA, Keppler BK. Conjugation of organoruthenium(II) 3-(1H-benzimidazol-2-yl)pyrazolo[3,4-b]pyridines and indolo[3,2-d]benzazepines to recombinant human serum albumin: a strategy to enhance cytotoxicity in cancer cells. Inorganic Chemistry. 50: 12669-79. PMID 22111668 DOI: 10.1021/Ic201801E  0.369
2011 Casini A, Messori L. Molecular mechanisms and proposed targets for selected anticancer gold compounds. Current Topics in Medicinal Chemistry. 11: 2647-60. PMID 22039866 DOI: 10.2174/156802611798040732  0.607
2011 Vergara E, Cerrada E, Clavel C, Casini A, Laguna M. Thiolato gold(I) complexes containing water-soluble phosphane ligands: a characterization of their chemical and biological properties. Dalton Transactions (Cambridge, England : 2003). 40: 10927-35. PMID 21904768 DOI: 10.1039/C1Dt10892A  0.431
2011 Gabbiani C, Casini A, Kelter G, Cocco F, Cinellu MA, Fiebig HH, Messori L. Mechanistic studies on two dinuclear organogold(III) compounds showing appreciable antiproliferative properties and a high redox stability. Metallomics : Integrated Biometal Science. 3: 1318-23. PMID 21887452 DOI: 10.1039/C1Mt00113B  0.586
2011 Wenzel M, Bertrand B, Eymin MJ, Comte V, Harvey JA, Richard P, Groessl M, Zava O, Amrouche H, Harvey PD, Le Gendre P, Picquet M, Casini A. Multinuclear cytotoxic metallodrugs: physicochemical characterization and biological properties of novel heteronuclear gold-titanium complexes. Inorganic Chemistry. 50: 9472-80. PMID 21875041 DOI: 10.1021/Ic201155Y  0.387
2011 Nowak-Sliwinska P, van Beijnum JR, Casini A, Nazarov AA, Wagnieres G, van den Bergh H, Dyson PJ, Griffioen AW. Organometallic ruthenium(II) arene compounds with antiangiogenic activity. Journal of Medicinal Chemistry. 54: 3895-902. PMID 21534534 DOI: 10.1021/Jm2002074  0.418
2011 Mendes F, Groessl M, Nazarov AA, Tsybin YO, Sava G, Santos I, Dyson PJ, Casini A. Metal-based inhibition of poly(ADP-ribose) polymerase--the guardian angel of DNA. Journal of Medicinal Chemistry. 54: 2196-206. PMID 21370912 DOI: 10.1021/Jm2000135  0.384
2011 Mügge C, Rothenburger C, Beyer A, Görls H, Gabbiani C, Casini A, Michelucci E, Landini I, Nobili S, Mini E, Messori L, Weigand W. Structure, solution chemistry, antiproliferative actions and protein binding properties of non-conventional platinum(II) compounds with sulfur and phosphorus donors. Dalton Transactions (Cambridge, England : 2003). 40: 2006-16. PMID 21212880 DOI: 10.1039/C0Dt00845A  0.598
2011 Marcon G, Casini A, Mura P, Messori L, Bergamo A, Orioli P. Biological Properties of IRIM, the Iridium(III) Analogue of (Imidazolium (Bisimidazole) Tetrachlororuthenate) (ICR). Metal-Based Drugs. 7: 195-200. PMID 18475945 DOI: 10.1155/Mbd.2000.195  0.556
2011 Ascone I, Messori L, Balerna A, Castellano C, Gabbiani C, Casini A, Marchioni C, Castellano AC. XAS/XRD complementary data on metallodrugs and their proteins complexes Acta Crystallographica Section A. 67: 517-517. DOI: 10.1107/S0108767311086909  0.515
2011 Gabbiani C, Mastrobuoni G, Sorrentino F, Dani B, Rigobello MP, Bindoli A, Cinellu MA, Pieraccini G, Messori L, Casini A. Thioredoxin reductase, an emerging target for anticancer metallodrugs. Enzyme inhibition by cytotoxic gold(iii) compounds studied with combined mass spectrometry and biochemical assays Medchemcomm. 2: 50-54. DOI: 10.1039/C0Md00181C  0.6
2011 Snelders DJM, Casini A, Edafe F, Van Koten G, Klein Gebbink RJM, Dyson PJ. Ruthenium(II) arene complexes with oligocationic triarylphosphine ligands: Synthesis, DNA interactions and in vitro properties Journal of Organometallic Chemistry. 696: 1108-1116. DOI: 10.1016/J.Jorganchem.2010.11.025  0.415
2011 Ang WH, Casini A, Sava G, Dyson PJ. Organometallic ruthenium-based antitumor compounds with novel modes of action Journal of Organometallic Chemistry. 696: 989-998. DOI: 10.1016/J.Jorganchem.2010.11.009  0.469
2010 Messori L, Casini A, Gabbiani C, Michelucci E, Cubo L, Ríos-Luci C, Padrón JM, Navarro-Ranninger C, Quiroga AG. Cytotoxic Profile and Peculiar Reactivity with Biomolecules of a Novel "Rule-Breaker" Iodidoplatinum(II) Complex. Acs Medicinal Chemistry Letters. 1: 381-5. PMID 24900222 DOI: 10.1021/Ml100081E  0.577
2010 Cinellu MA, Maiore L, Manassero M, Casini A, Arca M, Fiebig HH, Kelter G, Michelucci E, Pieraccini G, Gabbiani C, Messori L. [Au2(phen(2Me))2(μ-O)2](PF6)2, a Novel Dinuclear Gold(III) Complex Showing Excellent Antiproliferative Properties. Acs Medicinal Chemistry Letters. 1: 336-9. PMID 24900215 DOI: 10.1021/Ml100097F  0.637
2010 Messori L, Balerna A, Ascone I, Castellano C, Gabbiani C, Casini A, Marchioni C, Jaouen G, Congiu Castellano A. X-ray absorption spectroscopy studies of the adducts formed between cytotoxic gold compounds and two major serum proteins. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 16: 491-9. PMID 21181484 DOI: 10.1007/S00775-010-0748-5  0.554
2010 Groessl M, Terenghi M, Casini A, Elviri L, Lobinski R, Dyson PJ. Reactivity of anticancer metallodrugs with serum proteins: new insights from size exclusion chromatography-ICP-MS and ESI-MS. Journal of Analytical Atomic Spectrometry. 25: 305-313. PMID 21151827 DOI: 10.1039/B922701F  0.324
2010 Casini A, Temperini C, Gabbiani C, Supuran CT, Messori L. The x-ray structure of the adduct between NAMI-A and carbonic anhydrase provides insights into the reactivity of this metallodrug with proteins. Chemmedchem. 5: 1989-94. PMID 20931644 DOI: 10.1002/Cmdc.201000331  0.522
2010 Pelletier F, Comte V, Massard A, Wenzel M, Toulot S, Richard P, Picquet M, Le Gendre P, Zava O, Edafe F, Casini A, Dyson PJ. Development of bimetallic titanocene-ruthenium-arene complexes as anticancer agents: relationships between structural and biological properties. Journal of Medicinal Chemistry. 53: 6923-33. PMID 20822096 DOI: 10.1021/Jm1004804  0.393
2010 Cubo L, Groessl M, Dyson PJ, Quiroga AG, Navarro-Ranninger C, Casini A. Proteins as possible targets for cytotoxic trans-platinum(II) complexes with aliphatic amine ligands: Further exceptions to the DNA paradigm. Chemmedchem. 5: 1335-43. PMID 20564276 DOI: 10.1002/Cmdc.201000104  0.4
2010 Casini A, Edafe F, Erlandsson M, Gonsalvi L, Ciancetta A, Re N, Ienco A, Messori L, Peruzzini M, Dyson PJ. Rationalization of the inhibition activity of structurally related organometallic compounds against the drug target cathepsin B by DFT. Dalton Transactions (Cambridge, England : 2003). 39: 5556-63. PMID 20467693 DOI: 10.1039/C003218B  0.6
2010 Casini A, Diawara MC, Scopelliti R, Zakeeruddin SM, Grätzel M, Dyson PJ. Synthesis, characterisation and biological properties of gold(III) compounds with modified bipyridine and bipyridylamine ligands. Dalton Transactions (Cambridge, England : 2003). 39: 2239-45. PMID 20162197 DOI: 10.1039/B921019A  0.458
2010 Innocenti M, Salvietti E, Guidotti M, Casini A, Bellandi S, Foresti ML, Gabbiani C, Pozzi A, Zatta P, Messori L. Trace copper(II) or zinc(II) ions drastically modify the aggregation behavior of amyloid-beta1-42: an AFM study. Journal of Alzheimer's Disease : Jad. 19: 1323-9. PMID 20061619 DOI: 10.3233/Jad-2010-1338  0.477
2010 Mura P, Camalli M, Casini A, Gabbiani C, Messori L. Trans-cis-cis-[RuCl2(DMSO)2(2-amino-5-methyl-thiazole)2], (PMRu52), a novel ruthenium(II) compound acting as a strong inhibitor of cathepsin B. Journal of Inorganic Biochemistry. 104: 111-7. PMID 19939460 DOI: 10.1016/J.Jinorgbio.2009.10.002  0.594
2010 Vergara E, Casini A, Sorrentino F, Zava O, Cerrada E, Rigobello MP, Bindoli A, Laguna M, Dyson PJ. Anticancer therapeutics that target selenoenzymes: synthesis, characterization, in vitro cytotoxicity, and thioredoxin reductase inhibition of a series of gold(I) complexes containing hydrophilic phosphine ligands. Chemmedchem. 5: 96-102. PMID 19937669 DOI: 10.1002/Cmdc.200900370  0.447
2010 Nobili S, Mini E, Landini I, Gabbiani C, Casini A, Messori L. Gold compounds as anticancer agents: chemistry, cellular pharmacology, and preclinical studies. Medicinal Research Reviews. 30: 550-80. PMID 19634148 DOI: 10.1002/Med.20168  0.609
2010 Vergara E, Cerrada E, Casini A, Zava O, Laguna M, Dyson PJ. Antiproliferative Activity of Gold(I) Alkyne Complexes Containing Water-Soluble Phosphane Ligands Organometallics. 29: 2596-2603. DOI: 10.1021/Om100300A  0.457
2010 Gras M, Therrien B, Süss-Fink G, Casini A, Edafe F, Dyson PJ. Anticancer activity of new organo-ruthenium, rhodium and iridium complexes containing the 2-(pyridine-2-yl)thiazole N,N-chelating ligand Journal of Organometallic Chemistry. 695: 1119-1125. DOI: 10.1016/J.Jorganchem.2010.01.020  0.394
2010 Casini A, Hartinger CG, Nazarov AA, Dyson PJ. Organometallic Antitumour Agents with Alternative Modes of Action Topics in Organometallic Chemistry. 32: 57-80. DOI: 10.1007/978-3-642-13185-1_3  0.351
2010 Vergara E, Casini A, Sorrentino F, Zava O, Cerrada E, Rigobello M, Bindoli A, Laguna M, Dyson P. Inside Cover: Anticancer Therapeutics That Target Selenoenzymes: Synthesis, Characterization, in vitro Cytotoxicity, and Thioredoxin Reductase Inhibition of a Series of Gold(I) Complexes Containing Hydrophilic Phosphine Ligands (ChemMedChem 1/2010) Chemmedchem. 5: 2-2. DOI: 10.1002/Cmdc.200990065  0.417
2009 Casini A, Karotki A, Gabbiani C, Rugi F, Vašák M, Messori L, Dyson PJ. Reactivity of an antimetastatic organometallic ruthenium compound with metallothionein-2: relevance to the mechanism of action. Metallomics : Integrated Biometal Science. 1: 434-41. PMID 21305148 DOI: 10.1039/B909185H  0.555
2009 Cubo L, Casini A, Gabbiani C, Mastrobuoni G, Messori L, Jiménez-Barbero J, Navarro-Ranninger C, Quiroga AG. Solution behaviour and biomolecular interactions of two cytotoxic trans-platinum(II) complexes bearing aliphatic amine ligands Chemistry (Weinheim An Der Bergstrasse, Germany). 15: 9139-9146. PMID 19655350 DOI: 10.1002/Chem.200901090  0.575
2009 Casini A, Kelter G, Gabbiani C, Cinellu MA, Minghetti G, Fregona D, Fiebig HH, Messori L. Chemistry, antiproliferative properties, tumor selectivity, and molecular mechanisms of novel gold(III) compounds for cancer treatment: a systematic study. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 14: 1139-49. PMID 19543922 DOI: 10.1007/S00775-009-0558-9  0.615
2009 Grossi C, Francese S, Casini A, Rosi MC, Luccarini I, Fiorentini A, Gabbiani C, Messori L, Moneti G, Casamenti F. Clioquinol decreases amyloid-beta burden and reduces working memory impairment in a transgenic mouse model of Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 17: 423-40. PMID 19363260 DOI: 10.3233/Jad-2009-1063  0.497
2009 Casini A, Gabbiani C, Michelucci E, Pieraccini G, Moneti G, Dyson PJ, Messori L. Exploring metallodrug-protein interactions by mass spectrometry: comparisons between platinum coordination complexes and an organometallic ruthenium compound. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 14: 761-70. PMID 19288144 DOI: 10.1007/S00775-009-0489-5  0.568
2009 Gabbiani C, Messori L, Cinellu MA, Casini A, Mura P, Sannella AR, Severini C, Majori G, Bilia AR, Vincieri FF. Outstanding plasmodicidal properties within a small panel of metallic compounds: Hints for the development of new metal-based antimalarials. Journal of Inorganic Biochemistry. 103: 310-2. PMID 19027959 DOI: 10.1016/J.Jinorgbio.2008.10.004  0.602
2009 Bindoli A, Rigobello MP, Scutari G, Gabbiani C, Casini A, Messori L. Thioredoxin reductase: A target for gold compounds acting as potential anticancer drugs Coordination Chemistry Reviews. 253: 1692-1707. DOI: 10.1016/J.Ccr.2009.02.026  0.61
2008 Hartinger CG, Casini A, Duhot C, Tsybin YO, Messori L, Dyson PJ. Stability of an organometallic ruthenium-ubiquitin adduct in the presence of glutathione: relevance to antitumour activity. Journal of Inorganic Biochemistry. 102: 2136-41. PMID 18834634 DOI: 10.1016/J.Jinorgbio.2008.08.002  0.567
2008 Casini A, Gabbiani C, Sorrentino F, Rigobello MP, Bindoli A, Geldbach TJ, Marrone A, Re N, Hartinger CG, Dyson PJ, Messori L. Emerging protein targets for anticancer metallodrugs: inhibition of thioredoxin reductase and cathepsin B by antitumor ruthenium(II)-arene compounds. Journal of Medicinal Chemistry. 51: 6773-81. PMID 18834187 DOI: 10.1021/Jm8006678  0.593
2008 Chiellini C, Casini A, Cochet O, Gabbiani C, Ailhaud G, Dani C, Messori L, Amri EZ. The influence of auranofin, a clinically established antiarthritic gold drug, on bone metabolism: analysis of its effects on human multipotent adipose-derived stem cells, taken as a model. Chemistry & Biodiversity. 5: 1513-20. PMID 18729088 DOI: 10.1002/Cbdv.200890140  0.496
2008 Ascone I, Messori L, Casini A, Gabbiani C, Balerna A, Dell'Unto F, Castellano AC. Exploiting soft and hard X-ray absorption spectroscopy to characterize metallodrug/protein interactions: the binding of [trans-RuCl4(Im)(dimethylsulfoxide)][ImH] (Im = imidazole) to bovine serum albumin. Inorganic Chemistry. 47: 8629-34. PMID 18722420 DOI: 10.1021/Ic8001477  0.507
2008 Gabbiani C, Casini A, Mastrobuoni G, Kirshenbaum N, Moshel O, Pieraccini G, Moneti G, Messori L, Gibson D. Peculiar mechanistic and structural features of the carboplatin-cytochrome c system revealed by ESI-MS analysis Journal of Biological Inorganic Chemistry. 13: 755-764. PMID 18350322 DOI: 10.1007/S00775-008-0361-Z  0.534
2008 Gabbiani C, Casini A, Messori L, Guerri A, Cinellu MA, Minghetti G, Corsini M, Rosani C, Zanello P, Arca M. Structural characterization, solution studies, and DFT calculations on a series of binuclear gold(III) oxo complexes: relationships to biological properties. Inorganic Chemistry. 47: 2368-79. PMID 18314951 DOI: 10.1021/Ic701254S  0.558
2008 Sannella AR, Casini A, Gabbiani C, Messori L, Bilia AR, Vincieri FF, Majori G, Severini C. New uses for old drugs. Auranofin, a clinically established antiarthritic metallodrug, exhibits potent antimalarial effects in vitro: Mechanistic and pharmacological implications. Febs Letters. 582: 844-7. PMID 18294965 DOI: 10.1016/J.Febslet.2008.02.028  0.538
2008 Casini A, Guerri A, Gabbiani C, Messori L. Biophysical characterisation of adducts formed between anticancer metallodrugs and selected proteins: new insights from X-ray diffraction and mass spectrometry studies. Journal of Inorganic Biochemistry. 102: 995-1006. PMID 18289690 DOI: 10.1016/J.Jinorgbio.2007.12.022  0.558
2008 Casini A, Hartinger C, Gabbiani C, Mini E, Dyson PJ, Keppler BK, Messori L. Gold(III) compounds as anticancer agents: relevance of gold-protein interactions for their mechanism of action. Journal of Inorganic Biochemistry. 102: 564-75. PMID 18177942 DOI: 10.1016/J.Jinorgbio.2007.11.003  0.607
2008 Drago D, Bettella M, Bolognin S, Cendron L, Scancar J, Milacic R, Ricchelli F, Casini A, Messori L, Tognon G, Zatta P. Potential pathogenic role of beta-amyloid(1-42)-aluminum complex in Alzheimer's disease. The International Journal of Biochemistry & Cell Biology. 40: 731-46. PMID 18060826 DOI: 10.1016/J.Biocel.2007.10.014  0.469
2008 Bilia AR, Sannella AR, Vincieri FF, Messori L, Casini A, Gabbiani C, Severini C, Majori G. Antiplasmodial Effects of a few Selected Natural Flavonoids and their Modulation of Artemisinin Activity Natural Product Communications. 3: 1934578X0800301. DOI: 10.1177/1934578X0800301212  0.492
2008 Muniz-Miranda M, Pagliai M, Cardini G, Messori L, Bruni B, Casini A, Vaira MD, Schettino V. A multi-technique approach to predicting the molecular structure of cuprizone in the gas phase and in the crystalline state Crystengcomm. 10: 416-422. DOI: 10.1039/B715131D  0.496
2007 Pratesi A, Zanello P, Giorgi G, Messori L, Laschi F, Casini A, Corsini M, Gabbiani C, Orfei M, Rosani C, Ginanneschi M. New copper(II)/cyclic tetrapeptide system that easily oxidizes to copper(III) under atmospheric oxygen. Inorganic Chemistry. 46: 10038-40. PMID 17979273 DOI: 10.1021/Ic701411Y  0.52
2007 Mura P, Camalli M, Bindoli A, Sorrentino F, Casini A, Gabbiani C, Corsini M, Zanello P, Rigobello MP, Messori L. Activity of rat cytosolic thioredoxin reductase is strongly decreased by trans-[bis(2-amino-5- methylthiazole)tetrachlororuthenate(III)]: first report of relevant thioredoxin reductase inhibition for a ruthenium compound. Journal of Medicinal Chemistry. 50: 5871-4. PMID 17975904 DOI: 10.1021/Jm0708578  0.603
2007 Casini A, Gabbiani C, Mastrobuoni G, Pellicani RZ, Intini FP, Arnesano F, Natile G, Moneti G, Francese S, Messori L. Insights into the molecular mechanisms of protein platination from a case study: The reaction of anticancer platinum(II) iminoethers with horse heart cytochrome C Biochemistry. 46: 12220-12230. PMID 17924668 DOI: 10.1021/Bi701516Q  0.529
2007 Casini A, Mastrobuoni G, Terenghi M, Gabbiani C, Monzani E, Moneti G, Casella L, Messori L. Ruthenium anticancer drugs and proteins: A study of the interactions of the ruthenium(III) complex imidazolium trans-[tetrachloro(dimethyl sulfoxide)(imidazole)ruthenate(III)] with hen egg white lysozyme and horse heart cytochrome c Journal of Biological Inorganic Chemistry. 12: 1107-1117. PMID 17680283 DOI: 10.1007/S00775-007-0280-4  0.564
2007 Messori L, Casini A, Gabbiani C, Sorace L, Muniz-Miranda M, Zatta P. Unravelling the chemical nature of copper cuprizone. Dalton Transactions (Cambridge, England : 2003). 2112-4. PMID 17514330 DOI: 10.1039/B701896G  0.511
2007 Casini A, Mastrobuoni G, Ang WH, Gabbiani C, Pieraccini G, Moneti G, Dyson PJ, Messori L. ESI-MS characterisation of protein adducts of anticancer ruthenium(II)-arene PTA (RAPTA) complexes Chemmedchem. 2: 631-635. PMID 17366652 DOI: 10.1002/Cmdc.200600258  0.566
2007 Ciani L, Casini A, Gabbiani C, Ristori S, Messori L, Martini G. DOTAP/DOPE and DC-Chol/DOPE lipoplexes for gene delivery studied by circular dichroism and other biophysical techniques. Biophysical Chemistry. 127: 213-20. PMID 17350156 DOI: 10.1016/J.Bpc.2007.02.003  0.494
2007 Cini R, Defazio S, Tamasi G, Casolaro M, Messori L, Casini A, Morpurgo M, Hursthouse M. fac-{Ru(CO)3}2+-core complexes and design of metal-based drugs. synthesis, structure, and reactivity of Ru-thiazole derivative with serum proteins and absorption-release studies with acryloyl and silica hydrogels as carriers in physiological media. Inorganic Chemistry. 46: 79-92. PMID 17198415 DOI: 10.1021/Ic060755S  0.586
2007 Casini A, Mastrobuoni G, Temperini C, Gabbiani C, Francese S, Moneti G, Supuran CT, Scozzafava A, Messori L. ESI mass spectrometry and X-ray diffraction studies of adducts between anticancer platinum drugs and hen egg white lysozyme Chemical Communications. 156-158. PMID 17180231 DOI: 10.1039/B611122J  0.509
2007 Sannella AR, Messori L, Casini A, Francesco Vincieri F, Bilia AR, Majori G, Severini C. Antimalarial properties of green tea. Biochemical and Biophysical Research Communications. 353: 177-81. PMID 17174271 DOI: 10.1016/J.Bbrc.2006.12.005  0.504
2007 Sannella A, Messori L, Casini A, Vincieri F, Maiori G, Severini C, Bilia A. Modulation of the in vitro antimalarial effects of artemisinin by selected flavonoids and by reducing agents Planta Medica. 73. DOI: 10.1055/S-2007-986916  0.497
2007 Hartinger CG, Ang WH, Casini A, Messori L, Keppler BK, Dyson PJ. Mass spectrometric analysis of ubiquitin–platinum interactions of leading anticancer drugs: MALDI versus ESI Journal of Analytical Atomic Spectrometry. 22: 960-967. DOI: 10.1039/B703350H  0.539
2007 Gabbiani C, Casini A, Messori L. Gold(III) compounds as anticancer drugs Gold Bulletin. 40: 73-81. DOI: 10.1007/Bf03215296  0.629
2006 Casini A, Cinellu MA, Minghetti G, Gabbiani C, Coronnello M, Mini E, Messori L. Structural and solution chemistry, antiproliferative effects, and DNA and protein binding properties of a series of dinuclear gold(III) compounds with bipyridyl ligands. Journal of Medicinal Chemistry. 49: 5524-31. PMID 16942025 DOI: 10.1021/Jm060436A  0.611
2006 Casini A, Gabbiani C, Mastrobuoni G, Messori L, Moneti G, Pieraccini G. Exploring metallodrug-protein interactions by ESI mass spectrometry: the reaction of anticancer platinum drugs with horse heart cytochrome c Chemmedchem. 1: 413-417. PMID 16892376 DOI: 10.1002/Cmdc.200500079  0.496
2006 Calderone V, Casini A, Mangani S, Messori L, Orioli PL. Structural investigation of cisplatin-protein interactions: selective platination of His19 in a cuprozinc superoxide dismutase. Angewandte Chemie (International Ed. in English). 45: 1267-9. PMID 16416478 DOI: 10.1002/Anie.200502599  0.508
2006 Messori L, Gabbiani C, Casini A, Siragusa M, Vincieri FF, Bilia AR. The reaction of artemisinins with hemoglobin: a unified picture. Bioorganic & Medicinal Chemistry. 14: 2972-7. PMID 16412643 DOI: 10.1016/J.Bmc.2005.12.038  0.505
2005 Mincione F, Starnotti M, Masini E, Bacciottini L, Scrivanti C, Casini A, Vullo D, Scozzafava A, Supuran CT. Carbonic anhydrase inhibitors: design of thioureido sulfonamides with potent isozyme II and XII inhibitory properties and intraocular pressure lowering activity in a rabbit model of glaucoma. Bioorganic & Medicinal Chemistry Letters. 15: 3821-7. PMID 16039853 DOI: 10.1016/J.Bmcl.2005.06.054  0.303
2005 De Simone G, Di Fiore A, Menchise V, Pedone C, Antel J, Casini A, Scozzafava A, Wurl M, Supuran CT. Carbonic anhydrase inhibitors. Zonisamide is an effective inhibitor of the cytosolic isozyme II and mitochondrial isozyme V: solution and X-ray crystallographic studies. Bioorganic & Medicinal Chemistry Letters. 15: 2315-20. PMID 15837316 DOI: 10.1016/J.Bmcl.2005.03.032  0.34
2005 Di Fiore A, De Simone G, Menchise V, Pedone C, Casini A, Scozzafava A, Supuran CT. Carbonic anhydrase inhibitors: X-ray crystal structure of a benzenesulfonamide strong CA II and CA IX inhibitor bearing a pentafluorophenylaminothioureido tail in complex with isozyme II. Bioorganic & Medicinal Chemistry Letters. 15: 1937-42. PMID 15780637 DOI: 10.1016/J.Bmcl.2005.01.086  0.352
2005 Winum JY, Dogné JM, Casini A, de Leval X, Montero JL, Scozzafava A, Vullo D, Innocenti A, Supuran CT. Carbonic anhydrase inhibitors: synthesis and inhibition of cytosolic/membrane-associated carbonic anhydrase isozymes I, II, and IX with sulfonamides incorporating hydrazino moieties. Journal of Medicinal Chemistry. 48: 2121-5. PMID 15771455 DOI: 10.1021/Jm0494826  0.32
2004 Zimmerman S, Innocenti A, Casini A, Ferry JG, Scozzafava A, Supuran CT. Carbonic anhydrase inhibitors. Inhibition of the prokariotic beta and gamma-class enzymes from Archaea with sulfonamides. Bioorganic & Medicinal Chemistry Letters. 14: 6001-6. PMID 15546717 DOI: 10.1016/J.Bmcl.2004.09.085  0.317
2004 Bonnac L, Innocenti A, Winum JY, Casini A, Montero JL, Scozzafava A, Barragan V, Supuran CT. Carbonic anhydrase inhibitors: aliphatic N-phosphorylated sulfamates--a novel zinc-anchoring group leading to nanomolar inhibitors. Journal of Enzyme Inhibition and Medicinal Chemistry. 19: 275-8. PMID 15500000 DOI: 10.1080/14756360410001689522  0.347
2004 Galli A, Ceni E, Crabb DW, Mello T, Salzano R, Grappone C, Milani S, Surrenti E, Surrenti C, Casini A. Antidiabetic thiazolidinediones inhibit invasiveness of pancreatic cancer cells via PPARgamma independent mechanisms. Gut. 53: 1688-97. PMID 15479693 DOI: 10.1136/Gut.2003.031997  0.32
2004 Innocenti A, Casini A, Alcaro MC, Papini AM, Scozzafava A, Supuran CT. Carbonic anhydrase inhibitors: the first on-resin screening of a 4-sulfamoylphenylthiourea library. Journal of Medicinal Chemistry. 47: 5224-9. PMID 15456265 DOI: 10.1021/Jm049692I  0.306
2004 Supuran CT, Vullo D, Manole G, Casini A, Scozzafava A. Designing of novel carbonic anhydrase inhibitors and activators. Current Medicinal Chemistry. Cardiovascular and Hematological Agents. 2: 49-68. PMID 15328829 DOI: 10.2174/1568016043477305  0.3
2004 Supuran CT, Casini A, Mastrolorenzo A, Scozzafava A. COX-2 selective inhibitors, carbonic anhydrase inhibition and anticancer properties of sulfonamides belonging to this class of pharmacological agents. Mini Reviews in Medicinal Chemistry. 4: 625-32. PMID 15279596 DOI: 10.2174/1389557043403792  0.337
2004 Lehtonen JM, Parkkila S, Vullo D, Casini A, Scozzafava A, Supuran CT. Carbonic anhydrase inhibitors. Inhibition of cytosolic isozyme XIII with aromatic and heterocyclic sulfonamides: a novel target for the drug design. Bioorganic & Medicinal Chemistry Letters. 14: 3757-62. PMID 15203157 DOI: 10.1016/J.Bmcl.2004.04.106  0.326
2004 de Leval X, Ilies M, Casini A, Dogné JM, Scozzafava A, Masini E, Mincione F, Starnotti M, Supuran CT. Carbonic anhydrase inhibitors: synthesis and topical intraocular pressure lowering effects of fluorine-containing inhibitors devoid of enhanced reactivity. Journal of Medicinal Chemistry. 47: 2796-804. PMID 15139757 DOI: 10.1021/Jm031116J  0.349
2004 Dogné JM, de Leval X, Hanson J, Frederich M, Lambermont B, Ghuysen A, Casini A, Masereel B, Ruan KH, Pirotte B, Kolh P. New developments on thromboxane and prostacyclin modulators part I: thromboxane modulators. Current Medicinal Chemistry. 11: 1223-41. PMID 15134516 DOI: 10.2174/0929867043365260  0.314
2004 Abbate F, Casini A, Scozzafava A, Supuran CT. Carbonic anhydrase inhibitors: X-ray crystallographic structure of the adduct of human isozyme II with a topically acting antiglaucoma sulfonamide. Bioorganic & Medicinal Chemistry Letters. 14: 2357-2361. PMID 15081040 DOI: 10.1016/J.Bmcl.2004.01.096  0.356
2004 Weber A, Casini A, Heine A, Kuhn D, Supuran CT, Scozzafava aA, Klebe G. Unexpected nanomolar inhibition of carbonic anhydrase by COX-2-selective celecoxib: new pharmacological opportunities due to related binding site recognition. Journal of Medicinal Chemistry. 47: 550-557. PMID 14736236 DOI: 10.1021/Jm030912M  0.33
2004 Abbate F, Coetzee A, Casini A, Ciattini S, Scozzafava A, Supuran CT. Carbonic anhydrase inhibitors: X-ray crystallographic structure of the adduct of human isozyme II with the antipsychotic drug sulpiride. Bioorganic & Medicinal Chemistry Letters. 14: 337-341. PMID 14698154 DOI: 10.1016/J.Bmcl.2003.11.014  0.393
2004 Abbate F, Winum JY, Potter BV, Casini A, Montero JL, Scozzafava A, Supuran CT. Carbonic anhydrase inhibitors: X-ray crystallographic structure of the adduct of human isozyme II with EMATE, a dual inhibitor of carbonic anhydrases and steroid sulfatase. Bioorganic & Medicinal Chemistry Letters. 14: 231-4. PMID 14684333 DOI: 10.1016/J.Bmcl.2003.09.064  0.352
2004 Abbate F, Casini A, Owa T, Scozzafava A, Supuran CT. Carbonic anhydrase inhibitors: E7070, a sulfonamide anticancer agent, potently inhibits cytosolic isozymes I and II, and transmembrane, tumor-associated isozyme IX. Bioorganic & Medicinal Chemistry Letters. 14: 217-23. PMID 14684331 DOI: 10.1016/J.Bmcl.2003.09.062  0.362
2004 Abbate F, Casini A, Scozzafava A, Supuran CT. Carbonic anhydrase inhibitors: X-ray crystallographic structure of the adduct of human isozyme II with the perfluorobenzoyl analogue of methazolamide. Implications for the drug design of fluorinated inhibitors. Journal of Enzyme Inhibition and Medicinal Chemistry. 18: 303-8. PMID 14567544 DOI: 10.1080/1475636031000119337  0.376
2003 Winum †J, Vullo D, Casini A, Montero †J, Scozzafava aA, Supuran CT. Carbonic Anhydrase Inhibitors: Inhibition of Transmembrane, Tumor-Associated Isozyme IX, and Cytosolic Isozymes I and II with Aliphatic Sulfamates Journal of Medicinal Chemistry. 46: 5471-5477. PMID 14640555 DOI: 10.1021/Jm030911U  0.308
2003 Casini A, Scozzafava A, Mincione F, Menabuoni L, Starnotti M, Supuran CT. Carbonic anhydrase inhibitors: topically acting antiglaucoma sulfonamides incorporating esters and amides of 3- and 4-carboxybenzolamide. Bioorganic & Medicinal Chemistry Letters. 13: 2867-2873. PMID 14611846 DOI: 10.1016/S0960-894X(03)00580-8  0.32
2003 Casini A, Caccia S, Scozzafava A, Supuran CT. Carbonic anhydrase activators. The selective serotonin reuptake inhibitors fluoxetine, sertraline and citalopram are strong activators of isozymes I and II. Bioorganic & Medicinal Chemistry Letters. 13: 2765-2768. PMID 12873510 DOI: 10.1016/S0960-894X(03)00507-9  0.317
2003 Casini A, Abbate F, Scozzafava A, Supuran CT. Carbonic anhydrase inhibitors: X-ray crystallographic structure of the adduct of human isozyme II with a bis-sulfonamide-two heads are better than one? Bioorganic & Medicinal Chemistry Letters. 13: 2759-2763. PMID 12873509 DOI: 10.1016/S0960-894X(03)00508-0  0.338
2003 Supuran CT, Casini A, Scozzafava A. Protease inhibitors of the sulfonamide type: Anticancer, antiinflammatory, and antiviral agents Medicinal Research Reviews. 23: 535-558. PMID 12789686 DOI: 10.1002/Med.10047  0.354
2003 Winum †J, Vullo D, Casini A, Montero †J, Scozzafava aA, Supuran CT. Carbonic anhydrase inhibitors. Inhibition of cytosolic isozymes I and II and transmembrane, tumor-associated isozyme IX with sulfamates including EMATE also acting as steroid sulfatase inhibitors. Journal of Medicinal Chemistry. 46: 2197-2204. PMID 12747791 DOI: 10.1021/Jm021124K  0.305
2003 Casini A, Antel J, Abbate F, Scozzafava A, David S, Waldeck H, Schäfer S, Supuran CT. Carbonic anhydrase inhibitors: SAR and X-ray crystallographic study for the interaction of sugar sulfamates/sulfamides with isozymes I, II and IV. Bioorganic & Medicinal Chemistry Letters. 13: 841-5. PMID 12617904 DOI: 10.1016/S0960-894X(03)00029-5  0.379
2003 Casini A, Winum J, Montero J, Scozzafava A, Supuran CT. Carbonic anhydrase inhibitors: inhibition of cytosolic isozymes I and II with sulfamide derivatives. Bioorganic & Medicinal Chemistry Letters. 13: 837-840. PMID 12617903 DOI: 10.1016/S0960-894X(03)00028-3  0.356
2003 Maestrelli F, Mura P, Casini A, Mincione F, Scozzafava A, Supuran CT. Cyclodextrin complexes of sulfonamide carbonic anhydrase inhibitors as long-lasting topically acting antiglaucoma agents. Journal of Pharmaceutical Sciences. 91: 2211-9. PMID 12226848 DOI: 10.1002/Jps.10215  0.322
2002 Casini A, Scozzafava A, Supuran CT. Cysteine-modifying agents: a possible approach for effective anticancer and antiviral drugs. Environmental Health Perspectives. 110: 801-806. PMID 12426135 DOI: 10.1289/Ehp.02110S5801  0.339
2002 Casini A, Mincione F, Vullo D, Menabuoni L, Scozzafava A, Supuran CT. Carbonic anhydrase inhibitors with strong topical antiglaucoma properties incorporating a 4-(2-aminopyrimidin-4-yl-amino)-benzenesulfonamide scaffold. Journal of Enzyme Inhibition and Medicinal Chemistry. 17: 9-18. PMID 12365464 DOI: 10.1080/14756360290018602  0.303
2002 casini A, Scozzafava A, Mastrolorenzo A, Supuran CT. Sulfonamides and sulfonylated derivatives as anticancer agents. Current Cancer Drug Targets. 2: 55-75. PMID 12188921 DOI: 10.2174/1568009023334060  0.38
2002 Scozzafava A, Casini A, Supuran CT. Targeting cysteine residues of biomolecules: new approaches for the design of antiviral and anticancer drugs. Current Medicinal Chemistry. 9: 1167-1185. PMID 12052170 DOI: 10.2174/0929867023370077  0.339
2002 Casini A, Scozzafava A, Supuran CT. Sulfonamide derivatives with protease inhibitory action as anticancer, anti-inflammatory and antiviral agents Expert Opinion On Therapeutic Patents. 12: 1307-1327. DOI: 10.1517/13543776.12.9.1307  0.332
2001 Casini A, Messori L, Orioli P, Gielen M, Kemmer M, Willem R. Interactions of two cytotoxic organotin(IV) compounds with calf thymus DNA. Journal of Inorganic Biochemistry. 85: 297-300. PMID 11551387 DOI: 10.1016/S0162-0134(01)00215-X  0.554
2001 Mincione F, Starnotti M, Menabuoni L, Scozzafava A, Casini A, Supuran CT. Carbonic anhydrase inhibitors: 4-sulfamoyl-benzenecarboxamides and 4-chloro-3-sulfamoyl-benzenecarboxamides with strong topical antiglaucoma properties Bioorganic & Medicinal Chemistry Letters. 11: 1787-1791. PMID 11425561 DOI: 10.1016/S0960-894X(01)00303-1  0.312
2001 Casini A, Mincione F, Ilies MA, Menabuoni L, Scozzafava A, Supuran CT. Carbonic anhydrase inhibitors: synthesis and inhibition against isozymes I, II and IV of topically acting antiglaucoma sulfonamides incorporating cis-5-norbornene-endo-3-carboxy-2-carboxamido moieties. Journal of Enzyme Inhibition. 16: 113-23. PMID 11342280 DOI: 10.1080/14756360109162361  0.354
2001 Mura P, Casini A, Marcon G, Messori L. Synthesis, molecular structure and solution chemistry of the iridium(III) complex imidazolium [trans(bisimidazole)tetrachloro iridate(III)] (IRIM) Inorganica Chimica Acta. 312: 74-80. DOI: 10.1016/S0020-1693(00)00330-3  0.563
2000 Casini A, Scozzafava A, Mincione F, Menabuoni L, Ilies MA, Supuran CT. Carbonic anhydrase inhibitors: water-soluble 4-sulfamoylphenylthioureas as topical intraocular pressure-lowering agents with long-lasting effects. Journal of Medicinal Chemistry. 43: 4884-92. PMID 11123998 DOI: 10.1021/Jm001051+  0.327
2000 Ilies M, Supuran CT, Scozzafava A, Casini A, Mincione F, Menabuoni L, Caproiu MT, Maganu M, Banciu MD. Carbonic anhydrase inhibitors: sulfonamides incorporating furan-, thiophene- and pyrrole-carboxamido groups possess strong topical intraocular pressure lowering properties as aqueous suspensions. Bioorganic & Medicinal Chemistry. 8: 2145-2155. PMID 11003159 DOI: 10.1016/S0968-0896(00)00143-7  0.362
2000 Gallori E, Vettori C, Alessio E, Vilchez FG, Vilaplana R, Orioli P, Casini A, Messori L. DNA as a Possible Target for Antitumor Ruthenium(III) Complexes: A Spectroscopic and Molecular Biology Study of the Interactions of Two Representative Antineoplastic Ruthenium(III) Complexes with DNA Archives of Biochemistry and Biophysics. 376: 156-162. PMID 10729201 DOI: 10.1006/Abbi.1999.1654  0.557
2000 Ottaviani MF, Furini F, Casini A, Turro NJ, Jockusch S, Tomalia DA, Messori L. Formation of supramolecular structures between DNA and starburst dendrimers studied by EPR, CD, UV, and melting profiles Macromolecules. 33: 7842-7851. DOI: 10.1021/Ma000877I  0.505
2000 Messori L, Casini A, Vullo D, Haroutiunian S, Dalian E, Orioli P. Effects of two representative antitumor ruthenium(III) complexes on thermal denaturation profiles of DNA Inorganica Chimica Acta. 303: 283-286. DOI: 10.1016/S0020-1693(99)00528-9  0.547
Low-probability matches (unlikely to be authored by this person)
2004 Pastorekova S, Casini A, Scozzafava A, Vullo D, Pastorek J, Supuran CT. Carbonic anhydrase inhibitors: the first selective, membrane-impermeant inhibitors targeting the tumor-associated isozyme IX. Bioorganic & Medicinal Chemistry Letters. 14: 869-873. PMID 15012984 DOI: 10.1016/J.Bmcl.2003.12.029  0.299
2021 Pimpão C, Wragg D, Bonsignore R, Aikman B, Pedersen PA, Leoni S, Soveral G, Casini A. Mechanisms of irreversible aquaporin-10 inhibition by organogold compounds studied by combined biophysical methods and atomistic simulations. Metallomics : Integrated Biometal Science. PMID 34468767 DOI: 10.1093/mtomcs/mfab053  0.298
2020 Meier-Menches SM, Casini A. Design Strategies and Medicinal Applications of Metal-Peptidic Bioconjugates. Bioconjugate Chemistry. PMID 32243752 DOI: 10.1021/Acs.Bioconjchem.0C00152  0.297
2021 Chakraborty P, Oosterhuis D, Bonsignore R, Casini A, Olinga P, Scheffers DJ. An organogold compound as potential antimicrobial agent against drug resistant bacteria: initial mechanistic insights. Chemmedchem. PMID 34181818 DOI: 10.1002/cmdc.202100342  0.294
2005 Pastorekova S, Vullo D, Casini A, Scozzafava A, Pastorek J, Nishimori I, Supuran CT. Carbonic anhydrase inhibitors: Inhibition of the tumor-associated isozymes IX and XII with polyfluorinated aromatic/heterocyclic sulfonamides. Journal of Enzyme Inhibition and Medicinal Chemistry. 20: 211-7. PMID 16119190 DOI: 10.1080/14756360400028101  0.294
2023 de Andrade Querino AL, de Sousa AM, Thomas SR, de Lima GM, Dittz D, Casini A, do Monte-Neto RL, Silva H. Organogold(III)-dithiocarbamate compounds and their coordination analogues as anti-tumor and anti-leishmanial metallodrugs. Journal of Inorganic Biochemistry. 247: 112346. PMID 37536162 DOI: 10.1016/j.jinorgbio.2023.112346  0.292
2013 Avanti C, Hinrichs WL, Casini A, Eissens AC, Dam AV, Kedrov A, Driessen AJ, Frijlink HW, Permentier HP. The formation of oxytocin dimers is suppressed by the zinc-aspartate-oxytocin complex. Journal of Pharmaceutical Sciences. 102: 1734-41. PMID 23589380 DOI: 10.1002/Jps.23546  0.291
2017 Han J, Schmidt A, Zhang T, Permentier H, Groothuis GM, Bischoff R, Kühn FE, Horvatovich P, Casini A. Bioconjugation strategies to couple supramolecular exo-functionalized palladium cages to peptides for biomedical applications. Chemical Communications (Cambridge, England). PMID 28079225 DOI: 10.1039/C6Cc08937B  0.289
2002 Casini A, Scozzafava A, Mincione F, Menabuoni L, Supuran CT. Carbonic anhydrase inhibitors: Synthesis of water soluble sulfonamides incorporating a 4-sulfamoylphenylmethylthiourea scaffold, with potent intraocular pressure lowering properties Journal of Enzyme Inhibition and Medicinal Chemistry. 17: 333-343. PMID 12683750 DOI: 10.1080/1475636021000010950  0.286
2015 Daum S, Chekhun VF, Todor IN, Lukianova NY, Shvets YV, Sellner L, Putzker K, Lewis J, Zenz T, de Graaf IA, Groothuis GM, Casini A, Zozulia O, Hampel F, Mokhir A. Improved synthesis of N-benzylaminoferrocene-based prodrugs and evaluation of their toxicity and antileukemic activity. Journal of Medicinal Chemistry. 58: 2015-24. PMID 25633601 DOI: 10.1021/Jm5019548  0.283
2005 Fiore AD, Simone GD, Menchise V, Pedone C, Casini A, Scozzafava A, Supuran CT. The crystal structure of human CA II bound to a strong benzenesulfonamide inhibitor Acta Crystallographica Section A. 61: 216-216. DOI: 10.1107/S0108767305090811  0.282
2009 Spencer J, Casini A, Zava O, Rathnam RP, Velhanda SK, Pfeffer M, Callear SK, Hursthouse MB, Dyson PJ. Excellent correlation between cathepsin B inhibition and cytotoxicity for a series of palladacycles. Dalton Transactions (Cambridge, England : 2003). 10731-5. PMID 20023902 DOI: 10.1039/B912096C  0.282
2020 Sabir F, Di Pizio A, Loureiro-Dias MC, Casini A, Soveral G, Prista C. Insights into the Selectivity Mechanisms of Grapevine NIP Aquaporins. International Journal of Molecular Sciences. 21. PMID 32933135 DOI: 10.3390/Ijms21186697  0.276
2022 Aikman B, Bonsignore R, Woods B, Doellerer D, Scotti R, Schmidt C, Heidecker AA, Pöthig A, Sayers EJ, Jones AT, Casini A. Highly-fluorescent BODIPY-functionalised metallacages as drug delivery systems: synthesis, characterisation and cellular accumulation studies. Dalton Transactions (Cambridge, England : 2003). 51: 7476-7490. PMID 35470841 DOI: 10.1039/d2dt00337f  0.275
2019 Casini A, Crowley JD. Editorial: Supramolecular Metal-Based Entities for Biomedical and Biological Applications. Frontiers in Chemistry. 7: 293. PMID 31080795 DOI: 10.3389/Fchem.2019.00293  0.271
2019 van Dijk F, Teekamp N, Post E, Schuppan D, Kim YO, Zuidema J, Steendam R, Casini A, Horvatovich PL, Sijbrandi NJ, Frijlink HW, Hinrichs WLJ, Poelstra K, Beljaars L, Olinga P. The antifibrotic potential of a sustained release formulation of a PDGFβ-receptor targeted rho kinase inhibitor. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 30682444 DOI: 10.1016/J.Jconrel.2018.12.039  0.267
2019 Han J, Permentier H, Bischoff R, Groothuis G, Casini A, Horvatovich P. Imaging of protein distribution in tissues using mass spectrometry: An interdisciplinary challenge Trac Trends in Analytical Chemistry. 112: 13-28. DOI: 10.1016/J.Trac.2018.12.016  0.267
2016 Kaiser F, Schmidt A, Heydenreuter W, Altmann PJ, Casini A, Sieber SA, Kühn FE. Front Cover: Self-Assembled Palladium and Platinum Coordination Cages: Photophysical Studies and Anticancer Activity (Eur. J. Inorg. Chem. 33/2016) European Journal of Inorganic Chemistry. 2016: 5180-5180. DOI: 10.1002/Ejic.201670331  0.266
2003 Lehtonen J, Shen B, Vihinen M, Casini A, Scozzafava A, Supuran CT, Parkkila AK, Saarnio J, Kivelä AJ, Waheed A, Sly WS, Parkkila S. Characterization of CA XIII, a novel member of the carbonic anhydrase isozyme family. The Journal of Biological Chemistry. 279: 2719-27. PMID 14600151 DOI: 10.1074/Jbc.M308984200  0.263
2016 Soveral G, Casini A. Aquaporin modulators: a patent review (2010-2015). Expert Opinion On Therapeutic Patents. PMID 27622909 DOI: 10.1080/13543776.2017.1236085  0.261
2005 Casini A, Simone GD, Pedone C, Antel J, Scozzafava A, Supuran CT. X-ray crystallograpy of the antiepileptic drug zonisamide with CA II Acta Crystallographica Section A. 61: 242-242. DOI: 10.1107/S0108767305089695  0.26
2020 Leslie EM, Kaur G, Javed W, Ponomarenko O, Swanlund DP, Hu M, Summers KL, Casini A, Wenzel M, Casey JR, Cordat E, Pickering IJ, George GN. Human Red Blood Cell Uptake and Sequestration of Arsenite and Selenite: Evidence for the Formation of a Protective Glutathione Conjugate The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.06204  0.259
2024 da Silva IV, Pimpão C, Paccetti-Alves I, Thomas SR, Barateiro A, Casini A, Soveral G. Blockage of aquaporin-3 peroxiporin activity by organogold compounds affects melanoma cell adhesion, proliferation and migration. The Journal of Physiology. PMID 38323926 DOI: 10.1113/JP284155  0.258
2004 Svastová E, Hulíková A, Rafajová M, Zat'ovicová M, Gibadulinová A, Casini A, Cecchi A, Scozzafava A, Supuran CT, Pastorek J, Pastoreková S. Hypoxia activates the capacity of tumor-associated carbonic anhydrase IX to acidify extracellular pH. Febs Letters. 577: 439-45. PMID 15556624 DOI: 10.1016/J.Febslet.2004.10.043  0.258
1994 Casini A, Ceni E, Salzano R, Schuppan D, Milani S, Pellegrini G, Surrenti C. Regulation of Undulin Synthesis and Gene Expression in Human Fat-Storing Cells by Acetaldehyde and Transforming Growth Factor-β1: Comparison with Fibronectin Biochemical and Biophysical Research Communications. 199: 1019-1026. PMID 8135774 DOI: 10.1006/Bbrc.1994.1331  0.248
1993 Rotella CM, Galli G, Casini A, Bianchi S, Mannucci E, Cresci B, Schuppan D, Conti A, Brandi ML. Release of extracellular matrix components by bovine bone endothelial cells in continuous culture. Biochemical and Biophysical Research Communications. 190: 502-8. PMID 8427593 DOI: 10.1006/Bbrc.1993.1076  0.246
2017 Casini A, Orvig C, Correia JDG. Frontiers in radionuclide imaging and therapy, a chemical journey from naturally radioactive elements to targeted theranostic agents. Dalton Transactions (Cambridge, England : 2003). PMID 29057999 DOI: 10.1039/C7Dt90181J  0.242
2021 Pinho JO, da Silva IV, Amaral JD, Rodrigues CMP, Casini A, Soveral G, Manuela Gaspar M. Therapeutic potential of a copper complex loaded in pH-sensitive long circulating liposomes for colon cancer management. International Journal of Pharmaceutics. 120463. PMID 33711474 DOI: 10.1016/j.ijpharm.2021.120463  0.224
1991 Casini A, Galli G, Salzano R, Evangelista S, Maggi CA, Santicioli P, Rotella CM, Surrenti C. CGRP increases the production of glycosaminoglycans but not of collagen type I and III in cultures of rat fat-storing cells Regulatory Peptides. 34: 125. DOI: 10.1016/0167-0115(91)90466-T  0.221
2022 Thomas S, Yang W, Morgan DJ, Davies T, Li JJ, Fischer R, Huang J, Dimitratos N, Casini A. Bottom-up Synthesis of Water-Soluble Gold Nanoparticles Stabilized by N-heterocyclic Carbenes: From Structural Characterization to Applications. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 35801389 DOI: 10.1002/chem.202201575  0.217
2022 Pimpão C, Wragg D, da Silva IV, Casini A, Soveral G. Aquaglyceroporin Modulators as Emergent Pharmacological Molecules for Human Diseases. Frontiers in Molecular Biosciences. 9: 845237. PMID 35187089 DOI: 10.3389/fmolb.2022.845237  0.215
1976 Carelli I, Cardinali ME, Casini A, Arnone A. Electrochemical reduction of 3-cyano-1-methylpyridinium iodide, a nicotinamide adenine dinucleotide model compound. The Journal of Organic Chemistry. 41: 3967-9. PMID 186576 DOI: 10.1021/jo00887a007  0.206
2019 Casini A. In My Element: Gold Chemistry: a European Journal. 25: 12234-12234. DOI: 10.1002/Chem.201904008  0.199
2004 Winum JY, Casini A, Mincione F, Starnotti M, Montero JL, Scozzafava A, Supuran CT. Carbonic anhydrase inhibitors: N-(p-sulfamoylphenyl)-alpha-D-glycopyranosylamines as topically acting antiglaucoma agents in hypertensive rabbits. Bioorganic & Medicinal Chemistry Letters. 14: 225-9. PMID 14684332 DOI: 10.1016/j.bmcl.2003.09.063  0.198
1988 Casini A, Geppetti P, Maggi CA, Salzano R, Surrenti C. AbstractEffects of neurokinin A and calcitonin gene-related peptide on human peripheral blood leukocyte mitogenic response to phytohaemagglutinin Regulatory Peptides. 22: 44. DOI: 10.1016/0167-0115(88)90264-9  0.197
2023 Zhang JJ, Xu QJ, Schmidt C, Maaty MAAE, Song J, Yu C, Zhou J, Han K, Sun H, Casini A, Ott I, Wölfl S. Elucidating the Multimodal Anticancer Mechanism of an Organometallic Terpyridine Platinum(II) N-Heterocyclic Carbene Complex against Triple-Negative Breast Cancer In Vitro and In Vivo. Journal of Medicinal Chemistry. 66: 3995-4008. PMID 36898000 DOI: 10.1021/acs.jmedchem.2c01925  0.195
2023 Craig JS, Melidis L, Williams HD, Dettmer SJ, Heidecker AA, Altmann PJ, Guan S, Campbell C, Browning DF, Sigel RKO, Johannsen S, Egan RT, Aikman B, Casini A, Pöthig A, et al. Organometallic Pillarplexes That Bind DNA 4-Way Holliday Junctions and Forks. Journal of the American Chemical Society. PMID 37318835 DOI: 10.1021/jacs.3c00118  0.189
2022 Lutz TM, Kimna C, Casini A, Lieleg O. Bio-based and bio-inspired adhesives from animals and plants for biomedical applications. Materials Today. Bio. 13: 100203. PMID 35079700 DOI: 10.1016/j.mtbio.2022.100203  0.181
2022 Günther T, Konrad M, Stopper L, Kunert JP, Fischer S, Beck R, Casini A, Wester HJ. Optimization of the Pharmacokinetic Profile of [Tc]Tc-N-Bombesin Derivatives by Modification of the Pharmacophoric Gln-Trp Sequence. Pharmaceuticals (Basel, Switzerland). 15. PMID 36145354 DOI: 10.3390/ph15091133  0.181
2023 Siddiqui GA, Stebani JA, Wragg D, Koutsourelakis PS, Casini A, Gagliardi A. Application of Machine Learning Algorithms to Metadynamics for the Elucidation of the Binding Modes and Free Energy Landscape of Drug/Target Interactions: a Case Study. Chemistry (Weinheim An Der Bergstrasse, Germany). 29: e202302375. PMID 37555841 DOI: 10.1002/chem.202302375  0.172
2021 Guan S, Mayer DC, Jandl C, Weishäupl SJ, Casini A, Pöthig A. Investigation of Solvatomorphism and Its Photophysical Implications for Archetypal Trinuclear Au(1-Methylimidazolate). Molecules (Basel, Switzerland). 26. PMID 34361569 DOI: 10.3390/molecules26154404  0.172
2021 Bonsignore R, Thomas SR, Rigoulet M, Jandl C, Poethig A, Bourissou D, Barone G, Casini A. C-C Cross-couplings from a Cyclometalated Au(III) C^N complex: Mechanistic Insights and Synthetic Developments. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 34310783 DOI: 10.1002/chem.202102668  0.171
2021 Babak MV, Chong KR, Rapta P, Zannikou M, Tang HM, Reichert L, Chang MR, Kushnarev V, Heffeter P, Meier-Menches SM, Lim ZC, Yap JY, Casini A, Balyasnikova IV, Ang WH. Interfering with Metabolic Profile of Triple-Negative Breast Cancer using Rationally-Designed Metformin Prodrugs. Angewandte Chemie (International Ed. in English). PMID 33755286 DOI: 10.1002/anie.202102266  0.17
2004 Supuran CT, Vullo D, Manole G, Casini A, Scozzafava A. Designing of Novel Carbonic Anhydrase Inhibitors and Activators. Current Medicinal Chemistry. Cardiovascular and Hematological Agents. 2: 51-70. PMID 15320807  0.162
2003 Supuran CT, Scozzafava A, Casini A. Carbonic anhydrase inhibitors. Medicinal Research Reviews. 23: 146-89. PMID 12500287 DOI: 10.1002/med.10025  0.155
2021 Ge EJ, Bush AI, Casini A, Cobine PA, Cross JR, DeNicola GM, Dou QP, Franz KJ, Gohil VM, Gupta S, Kaler SG, Lutsenko S, Mittal V, Petris MJ, Polishchuk R, et al. Connecting copper and cancer: from transition metal signalling to metalloplasia. Nature Reviews. Cancer. PMID 34764459 DOI: 10.1038/s41568-021-00417-2  0.155
1996 Parola M, Pinzani M, Casini A, Leonarduzzi G, Marra F, Caligiuri A, Ceni E, Biondi P, Poli G, Dianzani MU. Induction of procollagen type I gene expression and synthesis in human hepatic stellate cells by 4-hydroxy-2,3-nonenal and other 4-hydroxy-2,3-alkenals is related to their molecular structure. Biochemical and Biophysical Research Communications. 222: 261-4. PMID 8670193 DOI: 10.1006/bbrc.1996.0732  0.144
1985 Gerson RJ, Casini A, Gilfor D, Serroni A, Farber JL. Oxygen-mediated cell injury in the killing of cultured hepatocytes by acetaminophen. Biochemical and Biophysical Research Communications. 126: 1129-37. PMID 3977907 DOI: 10.1016/0006-291X(85)90303-1  0.135
2020 Wragg D, Leoni S, Casini A. Aquaporin-driven hydrogen peroxide transport: a case of molecular mimicry? Rsc Chemical Biology. 1: 390-394. PMID 34458769 DOI: 10.1039/d0cb00160k  0.134
2022 Cosialls R, Simo' C, Borros S, Gçomez-Vallejo V, Schmidt C, Llop J, Cuenca AB, Casini A. PET imaging of self-assembled 18F-labelled Pd2L4 metallacages for anticancer drug delivery. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 36239701 DOI: 10.1002/chem.202202604  0.132
2020 da Silva IV, Cardoso C, Martínez-Banaclocha H, Casini A, Pelegrín P, Soveral G. Aquaporin-3 is involved in NLRP3-inflammasome activation contributing to the setting of inflammatory response. Cellular and Molecular Life Sciences : Cmls. PMID 33231721 DOI: 10.1007/s00018-020-03708-3  0.13
2021 Casini A, Vilar R. Editorial overview: Bioinorganic chemistry. Current Opinion in Chemical Biology. 61: A4-A5. PMID 33958103 DOI: 10.1016/j.cbpa.2021.04.007  0.12
1980 Carelli V, Liberatore F, Casini A, Mondelli R, Arnone A, Carelli I, Rotilio G, Mavelli I. Dimers of nicotinamide adenine dinucleotide: New evidence for the structure and the involvement in an enzymatic redox process Bioorganic Chemistry. 9: 342-351. DOI: 10.1016/0045-2068(80)90044-9  0.116
1991 Ragg E, Scaglioni L, Mondelli R, Carelli I, Casini A, Tortorella S. 1H-, 13C-, 31P-NMR studies and conformational analysis of NADP+, NADPH coenzymes and of dimers from electrochemical reduction of NADP+. Biochimica Et Biophysica Acta. 1076: 49-60. PMID 1824754 DOI: 10.1016/0167-4838(91)90218-O  0.114
1971 Liberatore F, Casini A, Carelli V, Arnone A, Mondelli R. Borohydride reduction of pyridinium salts. III. Formation of a Diels-Alder adduct in the reduction of 1-methyl-4-cyanopyridinium iodide. Tetrahedron Letters. 12: 2381-2384. DOI: 10.1016/S0040-4039(01)96869-8  0.105
2004 Mastrolorenzo A, Zuccati G, Massi D, Gabrielli MG, Casini A, Scozzafava A, Supuran CT. Immunohistochemical study of carbonic anhydrase isozymes in human skin. European Journal of Dermatology : Ejd. 13: 440-4. PMID 14693486  0.104
2021 Craven HM, Bonsignore R, Lenis V, Santi N, Berrar D, Swain M, Whiteland H, Casini A, Hoffmann KF. Identifying and validating the presence of Guanine-Quadruplexes (G4) within the blood fluke parasite Schistosoma mansoni. Plos Neglected Tropical Diseases. 15: e0008770. PMID 33600427 DOI: 10.1371/journal.pntd.0008770  0.104
2022 Dummert SV, Saini H, Hussain MZ, Yadava K, Jayaramulu K, Casini A, Fischer RA. Cyclodextrin metal-organic frameworks and derivatives: recent developments and applications. Chemical Society Reviews. PMID 35670434 DOI: 10.1039/d1cs00550b  0.102
2021 Stanley PM, Haimerl J, Thomas C, Urstoeger A, Schuster M, Shustova NB, Casini A, Rieger B, Warnan J, Fischer RA. Host-Guest Interactions in Metal-Organic Framework Isoreticular Series for Molecular Photocatalytic CO2 Reduction. Angewandte Chemie (International Ed. in English). PMID 34014024 DOI: 10.1002/anie.202102729  0.099
1989 Carelli V, Casini A, Desideri A, Finazzi Agrò A, Liberatore F, Tortorella S. Adriamycin-catalyzed aerobic photooxidation of NAD dimers to NAD+. Biochimica Et Biophysica Acta. 991: 25-9. PMID 2540842 DOI: 10.1016/0304-4165(89)90023-8  0.098
1993 Parola M, Pinzani M, Casini A, Albano E, Poli G, Gentilini A, Gentilini P, Dianzani MU. Stimulation of lipid peroxidation or 4-hydroxynonenal treatment increases procollagen alpha 1 (I) gene expression in human liver fat-storing cells. Biochemical and Biophysical Research Communications. 194: 1044-50. PMID 8352762 DOI: 10.1006/bbrc.1993.1927  0.098
1997 Parola M, Robino G, Bordone R, Leonarduzzi G, Casini A, Pinzani M, Neve E, Bellomo G, Dianzani MU, Ingelman-Sundberg M, Albano E. Detection of cytochrome P4503A (CYP3A) in human hepatic stellate cells. Biochemical and Biophysical Research Communications. 238: 420-4. PMID 9299524 DOI: 10.1006/BBRC.1997.7307  0.098
2024 Weingarten P, Thomas SR, Luiza de Andrade Querino A, Halama K, Kränzlein M, Casini A, Rieger B. A graft-to strategy of poly(vinylphosphonates) on dopazide-coated gold nanoparticles using catalyst activation. Rsc Advances. 14: 8145-8149. PMID 38464693 DOI: 10.1039/d4ra01116c  0.095
1981 Carelli I, Rosati R, Casini A. Electrochemical oxidation of dimers of nicotinamide adenine dinucleotide in aqueous medium Electrochimica Acta. 26: 1695-1697. DOI: 10.1016/0013-4686(81)85149-3  0.079
1983 Ramarli D, Canonica GW, Melioli G, Biagioni P, Nieri S, Casini A, Surrenti C. Abnormalities of immunocompetent cells in primary biliary cirrhosis. Scandinavian Journal of Immunology. 16: 201-7. PMID 6983114 DOI: 10.1111/j.1365-3083.1982.tb00715.x  0.077
2023 Holzleitner N, Cwojdzinski T, Beck R, Urtz-Urban N, Hillhouse CC, Grundler PV, van der Meulen NP, Talip Z, Ramaekers S, Van de Voorde M, Ponsard B, Casini A, Günther T. Preclinical Evaluation of Gastrin-Releasing Peptide Receptor Antagonists Labeled with Tb and Lu: A Comparative Study. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 38124121 DOI: 10.2967/jnumed.123.266233  0.077
1971 Liberatore F, Casini A, Carelli V, Arnone A, Mondelli R. Borohydride reduction of piridinium salts. IV. Simultaneous low temperature formation of (2+2) and (4+2) cycloadducts in the reduction of 1-methyl-4-cyano-pyridinium iodide Tetrahedron Letters. 12: 3829-3832. DOI: 10.1016/S0040-4039(01)97300-9  0.073
1983 Casini A, Martini F, Nieri S, Ramarli D, Franconi F, Surrenti C. High-performance liquid chromatographic determination of hydroxyproline after derivatization with 4-dimethylaminoazobenzene-4'-sulphonyl chloride. Journal of Chromatography. 249: 187-92. PMID 6816807 DOI: 10.1016/S0021-9673(00)80248-4  0.043
2021 Woods B, Silva RDM, Schmidt C, Wragg D, Cavaco M, Neves V, Ferreira VFC, Gano L, Morais TS, Mendes F, Correia JDG, Casini A. Bioconjugate Supramolecular Pd Metallacages Penetrate the Blood Brain Barrier and . Bioconjugate Chemistry. PMID 33440122 DOI: 10.1021/acs.bioconjchem.0c00659  0.025
2016 Casini A, Contel M. Preface. Journal of Inorganic Biochemistry. 165: 54-55. PMID 27938735 DOI: 10.1016/j.jinorgbio.2016.11.029  0.01
1965 Jahn RG, Von Jaskowsky W, Casini AJ. Gas‐Triggered Pinch Discharge Switch Review of Scientific Instruments. 36: 101-102. DOI: 10.1063/1.1719302  0.01
1963 Jahn RG, Von Jaskowsky W, Casini AJ. Gas‐Triggered Inverse Pinch Switch Review of Scientific Instruments. 34: 1439-1440. DOI: 10.1063/1.1718266  0.01
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