| Year |
Citation |
Score |
| 2023 |
Crouse B, Miller SM, Muelken P, Hicks L, Vigliaturo JR, Marker CL, Guedes AGP, Pentel PR, Evans JT, LeSage MG, Pravetoni M. A TLR7/8 agonist increases efficacy of anti-fentanyl vaccines in rodent and porcine models. Npj Vaccines. 8: 107. PMID 37488109 DOI: 10.1038/s41541-023-00697-9 |
0.545 |
|
| 2022 |
Hamid FA, Marker CL, Raleigh MD, Khaimraj A, Winston S, Pentel PR, Pravetoni M. Pre-clinical safety and toxicology profile of a candidate vaccine to treat oxycodone use disorder. Vaccine. 40: 3244-3252. PMID 35469698 DOI: 10.1016/j.vaccine.2022.03.053 |
0.832 |
|
| 2021 |
Raleigh MD, Beltraminelli N, Fallot S, LeSage MG, Saykao A, Pentel PR, Fuller S, Thisted T, Biesova Z, Horrigan S, Sampey D, Zhou B, Kalnik MW. Attenuating nicotine's effects with high affinity human anti-nicotine monoclonal antibodies. Plos One. 16: e0254247. PMID 34329335 DOI: 10.1371/journal.pone.0254247 |
0.814 |
|
| 2020 |
Raleigh MD, King SJ, Saykao AT, Baruffaldi F, Gradinati V, Winston S, Pentel PR, Pravetoni M. Functional
in vivo
characteristics of antibodies generated by an oxycodone vaccine The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.03354 |
0.817 |
|
| 2019 |
Hu Y, Smith D, Zhao Z, Harmon T, Pentel PR, Ehrich M, Zhang C. Alum as an adjuvant for nanoparticle based vaccines: A case study with a hybrid nanoparticle-based nicotine vaccine. Nanomedicine : Nanotechnology, Biology, and Medicine. 102023. PMID 31181264 DOI: 10.1016/J.Nano.2019.102023 |
0.655 |
|
| 2019 |
Zhao Z, Hu Y, Harmon T, Pentel P, Ehrich M, Zhang C. Effect of adjuvant release rate on the immunogenicity of nanoparticle-based vaccines: A case study with a nanoparticle-based nicotine vaccine. Molecular Pharmaceutics. PMID 31075204 DOI: 10.1021/Acs.Molpharmaceut.9B00279 |
0.635 |
|
| 2019 |
Baruffaldi F, Raleigh MD, King S, Roslawski M, Birnbaum A, Hassler C, Carroll FI, Runyon SP, Winston S, Pentel PR, Pravetoni M. Formulation and characterization of conjugate vaccines to reduce opioid use disorders suitable for pharmaceutical manufacturing and clinical evaluation. Molecular Pharmaceutics. PMID 31018096 DOI: 10.1021/Acs.Molpharmaceut.8B01296 |
0.828 |
|
| 2018 |
Raleigh MD, Baruffaldi F, Peterson SJ, Le Naour M, Harmon TM, Vigliaturo JR, Pentel PR, Pravetoni M. Vaccination reduces fentanyl distribution to the brain and fentanyl-induced toxicity in mice and rats: a potential role for a prophylactic vaccine against fentanyl-induced overdose. The Journal of Pharmacology and Experimental Therapeutics. PMID 30409833 DOI: 10.1124/Jpet.118.253674 |
0.817 |
|
| 2018 |
Hu Y, Zhao Z, Harmon T, Pentel PR, Ehrich M, Zhang C. Paradox of PEGylation in fabricating hybrid nanoparticle-based nicotine vaccines. Biomaterials. 182: 72-81. PMID 30107271 DOI: 10.1016/J.Biomaterials.2018.08.015 |
0.517 |
|
| 2018 |
Pentel PR, Raleigh MD, LeSage MG, Thisted T, Horrigan S, Biesova Z, Kalnik MW. The nicotine-degrading enzyme NicA2 reduces nicotine levels in blood, nicotine distribution to brain, and nicotine discrimination and reinforcement in rats. Bmc Biotechnology. 18: 46. PMID 30041697 DOI: 10.1186/S12896-018-0457-7 |
0.775 |
|
| 2018 |
Zhao Z, Hu Y, Harmon T, Pentel PR, Ehrich M, Zhang C. Hybrid nanoparticle-based nicotine nanovaccines: Boosting the immunological efficacy by conjugation of potent carrier proteins. Nanomedicine : Nanotechnology, Biology, and Medicine. PMID 29719216 DOI: 10.1016/J.Nano.2018.04.016 |
0.392 |
|
| 2018 |
Raleigh MD, Laudenbach M, Baruffaldi F, Peterson SJ, Roslawski MJ, Birnbaum AK, Carroll FI, Runyon SP, Winston S, Pentel PR, Pravetoni M. Opioid dose- and route-dependent efficacy of oxycodone and heroin vaccines in rats. The Journal of Pharmacology and Experimental Therapeutics. PMID 29535156 DOI: 10.1124/Jpet.117.247049 |
0.811 |
|
| 2018 |
Zhao Z, Harris B, Hu Y, Harmon T, Pentel PR, Ehrich M, Zhang C. Rational incorporation of molecular adjuvants into a hybrid nanoparticle-based nicotine vaccine for immunotherapy against nicotine addiction. Biomaterials. 155: 165-175. PMID 29179132 DOI: 10.1016/J.Biomaterials.2017.11.021 |
0.584 |
|
| 2017 |
Raleigh MD, Peterson SJ, Laudenbach M, Baruffaldi F, Carroll FI, Comer SD, Navarro HA, Langston TL, Runyon SP, Winston S, Pravetoni M, Pentel PR. Safety and efficacy of an oxycodone vaccine: Addressing some of the unique considerations posed by opioid abuse. Plos One. 12: e0184876. PMID 29194445 DOI: 10.1371/Journal.Pone.0184876 |
0.797 |
|
| 2017 |
Zhao Z, Hu Y, Harmon T, Pentel P, Ehrich M, Zhang C. Rationalization of a nanoparticle-based nicotine nanovaccine as an effective next-generation nicotine vaccine: A focus on hapten localization. Biomaterials. 138: 46-56. PMID 28551462 DOI: 10.1016/J.Biomaterials.2017.05.031 |
0.505 |
|
| 2017 |
Arutla V, Leal J, Liu X, Sokalingam S, Raleigh M, Adaralegbe A, Liu L, Pentel PR, Hecht SM, Chang Y. Pre-screening of nicotine hapten linkers in vitro to select hapten-conjugate vaccine candidates for pharmacokinetics evaluation in vivo. Acs Combinatorial Science. PMID 28383252 DOI: 10.1021/Acscombsci.6B00179 |
0.846 |
|
| 2017 |
Zhao Z, Powers K, Hu Y, Raleigh M, Pentel P, Zhang C. Engineering of a hybrid nanoparticle-based nicotine nanovaccine as a next-generation immunotherapeutic strategy against nicotine addiction: A focus on hapten density. Biomaterials. 123: 107-117. PMID 28167389 DOI: 10.1016/J.Biomaterials.2017.01.038 |
0.838 |
|
| 2016 |
Zhao Z, Hu Y, Hoerle R, Devine M, Raleigh M, Pentel P, Zhang C. A nanoparticle-based nicotine vaccine and the influence of particle size on its immunogenicity and efficacy. Nanomedicine : Nanotechnology, Biology, and Medicine. PMID 27520729 DOI: 10.1016/J.Nano.2016.07.015 |
0.855 |
|
| 2016 |
Mooney ME, Schmitz JM, Allen S, Grabowski J, Pentel P, Oliver A, Hatsukami DK. Bupropion and Naltrexone for Smoking Cessation: A Double-Blind Randomized Placebo-Controlled Clinical Trial. Clinical Pharmacology and Therapeutics. PMID 27213949 DOI: 10.1002/Cpt.402 |
0.347 |
|
| 2015 |
Zheng H, Hu Y, Huang W, de Villiers S, Pentel P, Zhang J, Dorn H, Ehrich M, Zhang C. Negatively Charged Carbon Nanohorn Supported Cationic Liposome Nanoparticles: A Novel Delivery Vehicle for Anti-Nicotine Vaccine. Journal of Biomedical Nanotechnology. 11: 2197-210. PMID 26510313 DOI: 10.1166/jbn.2015.2156 |
0.619 |
|
| 2015 |
Grebenstein PE, Burroughs D, Roiko SA, Pentel PR, LeSage MG. Predictors of the nicotine reinforcement threshold, compensation, and elasticity of demand in a rodent model of nicotine reduction policy. Drug and Alcohol Dependence. 151: 181-93. PMID 25891231 DOI: 10.1016/J.Drugalcdep.2015.03.030 |
0.787 |
|
| 2015 |
LeSage MG, Staley M, Pentel PR. Immunization increases the reinforcement threshold but not elasticity of demand for nicotine in an animal model of nicotine reduction policy Drug and Alcohol Dependence. 146: e174. DOI: 10.1016/j.drugalcdep.2014.09.390 |
0.354 |
|
| 2014 |
Raleigh MD, Pentel PR, LeSage MG. Pharmacokinetic correlates of the effects of a heroin vaccine on heroin self-administration in rats. Plos One. 9: e115696. PMID 25536404 DOI: 10.1371/Journal.Pone.0115696 |
0.84 |
|
| 2014 |
Pravetoni M, Pentel PR, Potter DN, Chartoff EH, Tally L, LeSage MG. Effects of an oxycodone conjugate vaccine on oxycodone self-administration and oxycodone-induced brain gene expression in rats. Plos One. 9: e101807. PMID 25025380 DOI: 10.1371/Journal.Pone.0101807 |
0.561 |
|
| 2014 |
Pravetoni M, Vervacke JS, Distefano MD, Tucker AM, Laudenbach M, Pentel PR. Effect of currently approved carriers and adjuvants on the pre-clinical efficacy of a conjugate vaccine against oxycodone in mice and rats. Plos One. 9: e96547. PMID 24797666 DOI: 10.1371/Journal.Pone.0096547 |
0.531 |
|
| 2014 |
Pentel PR, LeSage MG. New directions in nicotine vaccine design and use. Advances in Pharmacology (San Diego, Calif.). 69: 553-80. PMID 24484987 DOI: 10.1016/B978-0-12-420118-7.00014-7 |
0.635 |
|
| 2014 |
LeSage MG, Raleigh MD, Pravetoni M, Tally L, Pentel P. Effects of a morphine-conjugate vaccine on heroin self-administration in rats Drug and Alcohol Dependence. 140: e119. DOI: 10.1016/J.Drugalcdep.2014.02.341 |
0.81 |
|
| 2013 |
Cornish KE, de Villiers SH, Pravetoni M, Pentel PR. Immunogenicity of individual vaccine components in a bivalent nicotine vaccine differ according to vaccine formulation and administration conditions. Plos One. 8: e82557. PMID 24312662 DOI: 10.1371/Journal.Pone.0082557 |
0.839 |
|
| 2013 |
de Villiers SH, Cornish KE, Troska AJ, Pravetoni M, Pentel PR. Increased efficacy of a trivalent nicotine vaccine compared to a dose-matched monovalent vaccine when formulated with alum. Vaccine. 31: 6185-93. PMID 24176492 DOI: 10.1016/J.Vaccine.2013.10.051 |
0.836 |
|
| 2013 |
Pravetoni M, Le Naour M, Tucker AM, Harmon TM, Hawley TM, Portoghese PS, Pentel PR. Reduced antinociception of opioids in rats and mice by vaccination with immunogens containing oxycodone and hydrocodone haptens. Journal of Medicinal Chemistry. 56: 915-23. PMID 23249238 DOI: 10.1021/Jm3013745 |
0.49 |
|
| 2013 |
Jones JM, Raleigh MD, Pentel PR, Harmon TM, Keyler DE, Remmel RP, Birnbaum AK. Stability of heroin, 6-monoacetylmorphine, and morphine in biological samples and validation of an LC-MS assay for delayed analyses of pharmacokinetic samples in rats. Journal of Pharmaceutical and Biomedical Analysis. 74: 291-7. PMID 23245263 DOI: 10.1016/J.Jpba.2012.10.033 |
0.703 |
|
| 2013 |
Raleigh MD, Pravetoni M, Harris AC, Birnbaum AK, Pentel PR. Selective effects of a morphine conjugate vaccine on heroin and metabolite distribution and heroin-induced behaviors in rats. The Journal of Pharmacology and Experimental Therapeutics. 344: 397-406. PMID 23220743 DOI: 10.1124/Jpet.112.201194 |
0.819 |
|
| 2012 |
Chen X, Pravetoni M, Bhayana B, Pentel PR, Wu MX. High immunogenicity of nicotine vaccines obtained by intradermal delivery with safe adjuvants. Vaccine. 31: 159-64. PMID 23123021 DOI: 10.1016/J.Vaccine.2012.10.069 |
0.638 |
|
| 2012 |
LeSage MG, Shelley D, Pravetoni M, Pentel PR. Enhanced attenuation of nicotine discrimination in rats by combining nicotine-specific antibodies with a nicotinic receptor antagonist. Pharmacology, Biochemistry, and Behavior. 102: 157-62. PMID 22503967 DOI: 10.1016/J.Pbb.2012.03.026 |
0.454 |
|
| 2012 |
Pravetoni M, Le Naour M, Harmon TM, Tucker AM, Portoghese PS, Pentel PR. An oxycodone conjugate vaccine elicits drug-specific antibodies that reduce oxycodone distribution to brain and hot-plate analgesia. The Journal of Pharmacology and Experimental Therapeutics. 341: 225-32. PMID 22262924 DOI: 10.1124/Jpet.111.189506 |
0.549 |
|
| 2012 |
Pravetoni M, Keyler DE, Pidaparthi RR, Carroll FI, Runyon SP, Murtaugh MP, Earley CA, Pentel PR. Structurally distinct nicotine immunogens elicit antibodies with non-overlapping specificities. Biochemical Pharmacology. 83: 543-50. PMID 22100986 DOI: 10.1016/J.Bcp.2011.11.004 |
0.631 |
|
| 2012 |
Harris AC, Stepanov I, Pentel PR, Lesage MG. Delivery of nicotine in an extract of a smokeless tobacco product reduces its reinforcement-attenuating and discriminative stimulus effects in rats. Psychopharmacology. 220: 565-76. PMID 21960181 DOI: 10.1007/s00213-011-2514-y |
0.335 |
|
| 2011 |
Cornish KE, Harris AC, LeSage MG, Keyler DE, Burroughs D, Earley C, Pentel PR. Combined active and passive immunization against nicotine: minimizing monoclonal antibody requirements using a target antibody concentration strategy. International Immunopharmacology. 11: 1809-15. PMID 21802529 DOI: 10.1016/J.Intimp.2011.07.009 |
0.835 |
|
| 2011 |
Harris AC, Pentel PR, Burroughs D, Staley MD, Lesage MG. A lack of association between severity of nicotine withdrawal and individual differences in compensatory nicotine self-administration in rats. Psychopharmacology. 217: 153-66. PMID 21494791 DOI: 10.1007/s00213-011-2273-9 |
0.352 |
|
| 2011 |
Pravetoni M, Keyler DE, Raleigh MD, Harris AC, Lesage MG, Mattson CK, Pettersson S, Pentel PR. Vaccination against nicotine alters the distribution of nicotine delivered via cigarette smoke inhalation to rats. Biochemical Pharmacology. 81: 1164-70. PMID 21333633 DOI: 10.1016/J.Bcp.2011.02.004 |
0.841 |
|
| 2010 |
Harris AC, Mattson C, Lesage MG, Keyler DE, Pentel PR. Comparison of the behavioral effects of cigarette smoke and pure nicotine in rats. Pharmacology, Biochemistry, and Behavior. 96: 217-27. PMID 20494826 DOI: 10.1016/j.pbb.2010.05.008 |
0.372 |
|
| 2009 |
Harris AC, Pentel PR, LeSage MG. Correlates of individual differences in compensatory nicotine self-administration in rats following a decrease in nicotine unit dose. Psychopharmacology. 205: 599-611. PMID 19475400 DOI: 10.1007/s00213-009-1567-7 |
0.35 |
|
| 2009 |
Roiko SA, Harris AC, LeSage MG, Keyler DE, Pentel PR. Passive immunization with a nicotine-specific monoclonal antibody decreases brain nicotine levels but does not precipitate withdrawal in nicotine-dependent rats. Pharmacology, Biochemistry, and Behavior. 93: 105-11. PMID 19393688 DOI: 10.1016/J.Pbb.2009.04.011 |
0.837 |
|
| 2009 |
Pentel P. Immunotherapy for Nicotine Addiction The Canadian Journal of Addiction. 1: 35. DOI: 10.1097/02024458-200912000-00078 |
0.394 |
|
| 2008 |
Keyler DE, Roiko SA, Earley CA, Murtaugh MP, Pentel PR. Enhanced immunogenicity of a bivalent nicotine vaccine. International Immunopharmacology. 8: 1589-94. PMID 18656557 DOI: 10.1016/J.Intimp.2008.07.001 |
0.876 |
|
| 2008 |
Roiko SA, Harris AC, Keyler DE, Lesage MG, Zhang Y, Pentel PR. Combined active and passive immunization enhances the efficacy of immunotherapy against nicotine in rats. The Journal of Pharmacology and Experimental Therapeutics. 325: 985-93. PMID 18305013 DOI: 10.1124/Jpet.107.135111 |
0.873 |
|
| 2008 |
Harris AC, Burroughs D, Pentel PR, LeSage MG. Compensatory nicotine self-administration in rats during reduced access to nicotine: an animal model of smoking reduction. Experimental and Clinical Psychopharmacology. 16: 86-97. PMID 18266555 DOI: 10.1037/1064-1297.16.1.86 |
0.368 |
|
| 2007 |
Kotlyar M, Mendoza-Baumgart MI, Li ZZ, Pentel PR, Barnett BC, Feuer RM, Smith EA, Hatsukami DK. Nicotine pharmacokinetics and subjective effects of three potential reduced exposure products, moist snuff and nicotine lozenge. Tobacco Control. 16: 138-42. PMID 17400953 DOI: 10.1136/Tc.2006.018440 |
0.343 |
|
| 2007 |
Cao J, Belluzzi JD, Loughlin SE, Keyler DE, Pentel PR, Leslie FM. Acetaldehyde, a major constituent of tobacco smoke, enhances behavioral, endocrine, and neuronal responses to nicotine in adolescent and adult rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 32: 2025-35. PMID 17287824 DOI: 10.1038/Sj.Npp.1301327 |
0.356 |
|
| 2006 |
LeSage MG, Keyler DE, Pentel PR. Erratum to Current status of immunologic approaches to treating tobacco dependence: Vaccines and nicotine-specific antibodies. The Aaps Journal. 8: E622. PMID 28341938 DOI: 10.1208/aapsj080370c |
0.61 |
|
| 2006 |
LeSage MG, Gustaf E, Dufek MB, Pentel PR. Effects of maternal intravenous nicotine administration on locomotor behavior in pre-weanling rats. Pharmacology, Biochemistry, and Behavior. 85: 575-83. PMID 17141848 DOI: 10.1016/j.pbb.2006.10.012 |
0.379 |
|
| 2006 |
Pentel PR, Keyler DE, Chen Y, LeSage MG, Dufek MB, Le C, Leslie FM. Vaccination against nicotine does not prevent nicotine-induced changes in fetal nicotinic receptor binding and c-fos mRNA expression in rats. Neurotoxicology and Teratology. 28: 589-96. PMID 16996246 DOI: 10.1016/j.ntt.2006.08.001 |
0.582 |
|
| 2006 |
Keyler DE, Lesage MG, Dufek MB, Pentel PR. Changes in maternal and fetal nicotine distribution after maternal administration of monoclonal nicotine-specific antibody to rats. International Immunopharmacology. 6: 1665-72. PMID 16979120 DOI: 10.1016/J.INTIMP.2006.06.013 |
0.539 |
|
| 2006 |
Skott M, Andreassen TT, Ulrich-Vinther M, Chen X, Keyler DE, LeSage MG, Pentel PR, Bechtold JE, Soballe K. Tobacco extract but not nicotine impairs the mechanical strength of fracture healing in rats. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 24: 1472-9. PMID 16705735 DOI: 10.1002/jor.20187 |
0.315 |
|
| 2006 |
LeSage MG, Burroughs D, Pentel PR. Effects of nicotine withdrawal on performance under a progressive-ratio schedule of sucrose pellet delivery in rats. Pharmacology, Biochemistry, and Behavior. 83: 585-91. PMID 16643998 DOI: 10.1016/j.pbb.2006.03.021 |
0.308 |
|
| 2006 |
LeSage MG, Keyler DE, Pentel PR. Current status of immunologic approaches to treating tobacco dependence: vaccines and nicotine-specific antibodies. The Aaps Journal. 8: E65-75. PMID 16584135 DOI: 10.1208/aapsj080108 |
0.576 |
|
| 2006 |
Pentel PR, Dufek MB, Roiko SA, Lesage MG, Keyler DE. Differential effects of passive immunization with nicotine-specific antibodies on the acute and chronic distribution of nicotine to brain in rats. The Journal of Pharmacology and Experimental Therapeutics. 317: 660-6. PMID 16407464 DOI: 10.1124/jpet.105.097873 |
0.549 |
|
| 2006 |
LeSage MG, Keyler DE, Hieda Y, Collins G, Burroughs D, Le C, Pentel PR. Effects of a nicotine conjugate vaccine on the acquisition and maintenance of nicotine self-administration in rats Psychopharmacology. 184: 409-416. PMID 15991003 DOI: 10.1007/S00213-005-0027-2 |
0.625 |
|
| 2005 |
Hatsukami DK, Rennard S, Jorenby D, Fiore M, Koopmeiners J, de Vos A, Horwith G, Pentel PR. Safety and immunogenicity of a nicotine conjugate vaccine in current smokers. Clinical Pharmacology and Therapeutics. 78: 456-67. PMID 16321612 DOI: 10.1016/J.Clpt.2005.08.007 |
0.656 |
|
| 2005 |
Nekhayeva IA, Nanovskaya TN, Pentel PR, Keyler DE, Hankins GD, Ahmed MS. Effects of nicotine-specific antibodies, Nic311 and Nic-IgG, on the transfer of nicotine across the human placenta. Biochemical Pharmacology. 70: 1664-72. PMID 16223470 DOI: 10.1016/j.bcp.2005.08.013 |
0.467 |
|
| 2005 |
Keyler DE, Roiko SA, Benlhabib E, LeSage MG, St. Peter JV, Stewart S, Fuller S, Le CT, Pentel PR. Monoclonal nicotine-specific antibodies reduce nicotine distribution to brain in rats: Dose- and affinity-response relationships Drug Metabolism and Disposition. 33: 1056-1061. PMID 15843487 DOI: 10.1124/dmd.105.004234 |
0.552 |
|
| 2005 |
Keyler DE, Dufek MB, Calvin AD, Bramwell TJ, LeSage MG, Raphael DE, Ross CA, Le CT, Pentel PR. Reduced nicotine distribution from mother to fetal brain in rats vaccinated against nicotine: Time course and influence of nicotine dosing regimen Biochemical Pharmacology. 69: 1385-1395. PMID 15826609 DOI: 10.1016/j.bcp.2005.02.007 |
0.582 |
|
| 2004 |
LeSage MG, Burroughs D, Dufek M, Keyler DE, Pentel PR. Reinstatement of nicotine self-administration in rats by presentation of nicotine-paired stimuli, but not nicotine priming. Pharmacology, Biochemistry, and Behavior. 79: 507-13. PMID 15582022 DOI: 10.1016/j.pbb.2004.09.002 |
0.352 |
|
| 2004 |
Satoskar SD, Keyler DE, LeSage MG, Raphael DE, Ross CA, Pentel PR. Tissue-dependent effects of immunization with a nicotine conjugate vaccine on the distribution of nicotine in rats. International Immunopharmacology. 3: 957-70. PMID 12810353 DOI: 10.1016/S1567-5769(03)00094-8 |
0.637 |
|
| 2003 |
Keyler D, Pentel PR, Kuehl G, Collins G, Murphy SE. Effects of nicotine infusion on the metabolism of the tobacco carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in rats. Cancer Letters. 202: 1-9. PMID 14643020 DOI: 10.1016/J.Canlet.2003.07.004 |
0.371 |
|
| 2003 |
LeSage MG, Keyler DE, Collins G, Pentel PR. Effects of continuous nicotine infusion on nicotine self-administration in rats: Relationship between continuously infused and self-administered nicotine doses and serum concentrations Psychopharmacology. 170: 278-286. PMID 12898121 DOI: 10.1007/S00213-003-1539-2 |
0.408 |
|
| 2003 |
Hatsukami DK, Jensen J, Brauer LH, Mooney M, Schulte S, Sofuoglu M, Pentel PR. Lack of effect of 5HT3 antagonist in mediating subjective and behavioral responses to cotinine. Pharmacology, Biochemistry, and Behavior. 75: 1-7. PMID 12759107 DOI: 10.1016/S0091-3057(03)00035-2 |
0.303 |
|
| 2003 |
Keyler DE, Shoeman D, LeSage MG, Calvin AD, Pentel PR. Maternal vaccination against nicotine reduces nicotine distribution to fetal brain in rats. The Journal of Pharmacology and Experimental Therapeutics. 305: 587-92. PMID 12606612 DOI: 10.1124/JPET.102.046805 |
0.593 |
|
| 2002 |
Pentel P, Malin D. A vaccine for nicotine dependence: targeting the drug rather than the brain. Respiration; International Review of Thoracic Diseases. 69: 193-7. PMID 12097758 DOI: 10.1159/000063617 |
0.698 |
|
| 2002 |
LeSage MG, Keyler DE, Shoeman D, Raphael D, Collins G, Pentel PR. Continuous nicotine infusion reduces nicotine self-administration in rats with 23-h/day access to nicotine Pharmacology Biochemistry and Behavior. 72: 279-289. PMID 11900798 DOI: 10.1016/S0091-3057(01)00775-4 |
0.404 |
|
| 2002 |
Tuncok Y, Hieda Y, Keyler DE, Brown S, Ennifar S, Fattom A, Pentel PR. Inhibition of nicotine-induced seizures in rats by combining vaccination against nicotine with chronic nicotine infusion. Experimental and Clinical Psychopharmacology. 9: 228-34. PMID 11518099 DOI: 10.1037//1064-1297.9.2.228 |
0.654 |
|
| 2001 |
Tunock Y, Hieda Y, Keyler DE, Brown S, Ennifar S, Fattom A, Pentel PR. Inhibition of nicotine-induced seizures in rats by combining vaccination against nicotine with chronic nicotine infusion. Experimental and Clinical Psychopharmacology. 9: 228-234. DOI: 10.1037/1064-1297.9.2.228 |
0.533 |
|
| 2000 |
Keyler DE, Hieda Y, St Peter J, Pentel PR. Altered disposition of repeated nicotine doses in rats immunized against nicotine. Nicotine & Tobacco Research : Official Journal of the Society For Research On Nicotine and Tobacco. 1: 241-9. PMID 11072421 DOI: 10.1080/14622299050011361 |
0.475 |
|
| 2000 |
Hieda Y, Keyler DE, Ennifar S, Fattom A, Pentel PR. Vaccination against nicotine during continued nicotine administration in rats: immunogenicity of the vaccine and effects on nicotine distribution to brain. International Journal of Immunopharmacology. 22: 809-19. PMID 10963853 DOI: 10.1016/S0192-0561(00)00042-4 |
0.643 |
|
| 2000 |
Pentel PR, Malin DH, Ennifar S, Hieda Y, Keyler DE, Lake JR, Milstein JR, Basham LE, Coy RT, Moon JW, Naso R, Fattom A. A nicotine conjugate vaccine reduces nicotine distribution to brain and attenuates its behavioral and cardiovascular effects in rats. Pharmacology, Biochemistry, and Behavior. 65: 191-8. PMID 10638653 DOI: 10.1016/S0091-3057(99)00206-3 |
0.565 |
|
| 1998 |
Hatsukami D, Lexau B, Nelson D, Pentel PR, Sofuoglu M, Goldman A. Effects of cotinine on cigarette self-administration. Psychopharmacology. 138: 184-9. PMID 9718288 DOI: 10.1007/S002130050661 |
0.344 |
|
| 1998 |
Hatsukami D, Pentel PR, Jensen J, Nelson D, Allen SS, Goldman A, Rafael D. Cotinine: Effects with and without nicotine Psychopharmacology. 135: 141-150. PMID 9497019 DOI: 10.1007/S002130050495 |
0.358 |
|
| 1990 |
Keyler D, Brunn G, Pentel P. Monoclonal antibody effects on imipramine distribution in rats Annals of Emergency Medicine. 19: 629. DOI: 10.1016/S0196-0644(05)82455-2 |
0.345 |
|
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