| Year |
Citation |
Score |
| 2021 |
Dhara D, Dhara A, Bennett J, Murphy PV. Cyclisations and Strategies for Stereoselective Synthesis of Piperidine Iminosugars. Chemical Record (New York, N.Y.). 21: 2958-2979. PMID 34713557 DOI: 10.1002/tcr.202100221 |
0.438 |
|
| 2020 |
Sweeney S, McArdle P, Taciak B, Robakiewicz S, Król M, Murphy PV. Migrastatin analogues with an (E)-alkene at the ring C-3: synthesis, conformational analysis and biological evaluation Arkivoc. 2021: 51-64. DOI: 10.24820/Ark.5550190.P011.261 |
0.449 |
|
| 2020 |
Fox KA, Chadda R, Cardona F, Barron S, McArdle P, Murphy PV. Building blocks from monosaccharides for synthesis of scaffolds, including macrocycles. Application of allylic azide rearrangement, azide-alkyne cycloaddition and ring closing metathesis Tetrahedron. 76: 131495. DOI: 10.1016/J.Tet.2020.131495 |
0.498 |
|
| 2020 |
Chadda R, Murphy PV. Cover Feature: A Route to 1-Deoxynojirimycin and 1-Deoxymannojirimycin Derivatives with Quaternary Centers Adjacent to the Ring Nitrogen from Methyl α-d
-Mannopyranoside (Eur. J. Org. Chem. 16/2020) European Journal of Organic Chemistry. 2020: 2307-2307. DOI: 10.1002/Ejoc.202000478 |
0.443 |
|
| 2020 |
Chadda R, Murphy PV. A Route to 1-Deoxynojirimycin and 1-Deoxymannojirimycin Derivatives with Quaternary Centers Adjacent to the Ring Nitrogen from Methyl α-d
-Mannopyranoside European Journal of Organic Chemistry. 2020: 2389-2398. DOI: 10.1002/Ejoc.201901875 |
0.444 |
|
| 2019 |
Negi A, Reilly CO, Jarikote DV, Zhou J, Murphy PV. Multi-targeting protein-protein interaction inhibitors: Evolution of macrocyclic ligands with embedded carbohydrates (MECs) to improve selectivity. European Journal of Medicinal Chemistry. 176: 292-309. PMID 31112891 DOI: 10.1016/J.Ejmech.2019.04.064 |
0.405 |
|
| 2019 |
Kutzner TJ, Gabba A, FitzGerald FG, Shilova NV, García Caballero G, Ludwig AK, Manning JC, Knospe C, Kaltner H, Sinowatz F, Murphy PV, Cudic M, Bovin NV, Gabius HJ. How altering the modular architecture affects aspects of lectin activity: case study on human galectin-1. Glycobiology. PMID 31091305 DOI: 10.1093/Glycob/Cwz034 |
0.406 |
|
| 2019 |
Doyle LM, Meany FB, Murphy PV. Lewis acid promoted anomerisation of alkyl O- and S-xylo-, arabino- and fucopyranosides. Carbohydrate Research. 471: 85-94. PMID 30508660 DOI: 10.1016/J.Carres.2018.11.010 |
0.407 |
|
| 2019 |
Negi A, Zhou J, Sweeney S, Murphy PV. Ligand design for somatostatin receptor isoforms 4 and 5. European Journal of Medicinal Chemistry. 163: 148-159. PMID 30503939 DOI: 10.1016/J.Ejmech.2018.11.030 |
0.333 |
|
| 2019 |
Roux A, Loffredo S, Ferrara AL, Murphy PV. Synthesis and biological evaluation of S-simplexides and other analogues of simplexide Pure and Applied Chemistry. 91: 1257-1276. DOI: 10.1515/Pac-2019-0218 |
0.362 |
|
| 2018 |
Zhou J, Negi A, Mirallai SI, Warta R, Herold-Mende C, Carty MP, Ye XS, Murphy PV. N-Alkyl-1,5-dideoxy-1,5-imino-l-fucitols as fucosidase inhibitors: Synthesis, molecular modelling and activity against cancer cell lines. Bioorganic Chemistry. 84: 418-433. PMID 30554081 DOI: 10.1016/J.Bioorg.2018.12.003 |
0.302 |
|
| 2018 |
Kerins L, Byrne S, Gabba A, Murphy PV. Anomer Preferences for Glucuronic and Galacturonic Acid and Derivatives and Influence of Electron Withdrawing Substituents. The Journal of Organic Chemistry. PMID 29969902 DOI: 10.1021/Acs.Joc.8B00610 |
0.372 |
|
| 2018 |
Farrell MP, Doyle LM, Murphy PV. Influence of acyl groups on glucopyranoside reactivity in Lewis acid promoted anomerisation Tetrahedron Letters. 59: 2726-2731. DOI: 10.1016/J.Tetlet.2018.05.076 |
0.339 |
|
| 2017 |
Doyle LM, O'Sullivan S, Di Salvo C, McKinney M, McArdle P, Murphy PV. Stereoselective Epimerizations of Glycosyl Thiols. Organic Letters. PMID 29039672 DOI: 10.1021/Acs.Orglett.7B02760 |
0.346 |
|
| 2017 |
Murphy P, Chadda R, McArdle P. Allylic Azide Rearrangement in Tandem with Intramolecular Huisgen Cycloaddition for Iminosugar and Glycomimetic Synthesis: Functionalized Piperidine, Pyrrolidine, and Pyrrolotriazoles from d-Mannose Synthesis. 49: 2138-2152. DOI: 10.1055/S-0036-1588791 |
0.305 |
|
| 2017 |
Mahajan N, Chadda R, Calabro K, Solanki H, O' Connell E, Murphy PV, Thomas OP. Isolation and synthesis of pygmanilines, phenylurea derivatives from the Northeastern Atlantic lichen Lichina pygmaea Tetrahedron Letters. 58: 1237-1239. DOI: 10.1016/J.Tetlet.2017.02.037 |
0.337 |
|
| 2016 |
Roy R, Cao Y, Kaltner H, Kottari N, Shiao TC, Belkhadem K, André S, Manning JC, Murphy PV, Gabius HJ. Teaming up synthetic chemistry and histochemistry for activity screening in galectin-directed inhibitor design. Histochemistry and Cell Biology. PMID 28013366 DOI: 10.1007/S00418-016-1525-5 |
0.338 |
|
| 2016 |
Lo Re D, Jones L, Giralt E, Murphy PV. Synthesis of an orthogonally protected polyhydroxylated cyclopentene from L-sorbose. Chemistry, An Asian Journal. PMID 27304425 DOI: 10.1002/Asia.201600736 |
0.372 |
|
| 2016 |
Roy R, Murphy PV, Gabius HJ. Multivalent Carbohydrate-Lectin Interactions: How Synthetic Chemistry Enables Insights into Nanometric Recognition. Molecules (Basel, Switzerland). 21. PMID 27187342 DOI: 10.3390/Molecules21050629 |
0.325 |
|
| 2016 |
McDonagh AW, Mahon MF, Murphy PV. Lewis Acid Induced Anomerization of Se-Glycosides. Application to Synthesis of α-Se-GalCer. Organic Letters. 18: 552-5. PMID 26794638 DOI: 10.1021/Acs.Orglett.5B03591 |
0.412 |
|
| 2016 |
Sweeney SM, Bullen GA, Gillis RB, Adams GG, Rowe AJ, Harding SE, Tucker JHR, Peacock AFA, Murphy PV. Coiled coil type neoglycoproteins presenting three lactose residues Tetrahedron Letters. 57: 1414-1417. DOI: 10.1016/J.Tetlet.2016.02.005 |
0.307 |
|
| 2016 |
Gabba A, Robakiewicz S, Taciak B, Ulewicz K, Broggini G, Rastelli G, Krol M, Murphy PV, Passarella D. Synthesis and Biological Evaluation of Migrastatin Macrotriazoles European Journal of Organic Chemistry. 2017: 60-69. DOI: 10.1002/Ejoc.201600988 |
0.408 |
|
| 2015 |
André S, Kaltner H, Kayser K, Murphy PV, Gabius HJ. Merging carbohydrate chemistry with lectin histochemistry to study inhibition of lectin binding by glycoclusters in the natural tissue context. Histochemistry and Cell Biology. PMID 26553286 DOI: 10.1007/S00418-015-1383-6 |
0.326 |
|
| 2015 |
Lo Re D, Zhou Y, Mucha J, Jones LF, Leahy L, Santocanale C, Krol M, Murphy PV. Synthesis of Migrastatin Analogues as Inhibitors of Tumour Cell Migration: Exploring Structural Change in and on the Macrocyclic Ring. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 26531227 DOI: 10.1002/Chem.201502861 |
0.413 |
|
| 2015 |
Swanson MD, Boudreaux DM, Salmon L, Chugh J, Winter HC, Meagher JL, André S, Murphy PV, Oscarson S, Roy R, King S, Kaplan MH, Goldstein IJ, Tarbet EB, Hurst BL, et al. Engineering a Therapeutic Lectin by Uncoupling Mitogenicity from Antiviral Activity. Cell. 163: 746-58. PMID 26496612 DOI: 10.1016/J.Cell.2015.09.056 |
0.338 |
|
| 2015 |
André S, O'Sullivan S, Koller C, Murphy PV, Gabius HJ. Bi- to tetravalent glycoclusters presenting GlcNAc/GalNAc as inhibitors: from plant agglutinins to human macrophage galactose-type lectin (CD301) and galectins. Organic & Biomolecular Chemistry. 13: 4190-203. PMID 25721929 DOI: 10.1039/C5Ob00048C |
0.384 |
|
| 2015 |
André S, Kaltner H, Manning JC, Murphy PV, Gabius HJ. Lectins: getting familiar with translators of the sugar code. Molecules (Basel, Switzerland). 20: 1788-823. PMID 25621423 DOI: 10.3390/Molecules20021788 |
0.318 |
|
| 2015 |
André S, O'Sullivan S, Gabius HJ, Murphy PV. Glycoclusters as lectin inhibitors: Comparative analysis on two plant agglutinins with different folding as a step towards rules for selectivity Tetrahedron. 71: 6867-6880. DOI: 10.1016/J.Tet.2015.07.020 |
0.36 |
|
| 2015 |
Lo Re D, Zhou Y, Mucha J, Jones LF, Leahy L, Santocanale C, Krol M, Murphy PV. Cover Picture: Synthesis of Migrastatin Analogues as Inhibitors of Tumour Cell Migration: Exploring Structural Change in and on the Macrocyclic Ring (Chem. Eur. J. 50/2015) Chemistry - a European Journal. 21: 17989-17989. DOI: 10.1002/Chem.201585001 |
0.388 |
|
| 2014 |
Lo Re D, Zhou Y, Nobis M, Anderson KI, Murphy PV. Synthesis of migrastatin and its macroketone analogue and in vivo FRAP analysis of the macroketone on E-cadherin dynamics. Chembiochem : a European Journal of Chemical Biology. 15: 1459-64. PMID 24919421 DOI: 10.1002/Cbic.201402061 |
0.341 |
|
| 2014 |
André S, Wang GN, Gabius HJ, Murphy PV. Combining glycocluster synthesis with protein engineering: an approach to probe into the significance of linker length in a tandem-repeat-type lectin (galectin-4). Carbohydrate Research. 389: 25-38. PMID 24698724 DOI: 10.1016/J.Carres.2013.12.024 |
0.345 |
|
| 2014 |
Barron S, Murphy PV. Synthesis of iminosugar derivatives presenting naphthyl and alkyl amine interacting groups and binding to somatostatin receptors Medchemcomm. 5: 1150-1158. DOI: 10.1039/C4Md00074A |
0.407 |
|
| 2014 |
McDonagh AW, Murphy PV. Synthesis of α-galactosyl ceramide analogues with an α-triazole at the anomeric carbon Tetrahedron. 70: 3191-3196. DOI: 10.1016/J.Tet.2014.03.029 |
0.332 |
|
| 2013 |
Farrell M, Zhou J, Murphy PV. Regiospecific anomerisation of acylated glycosyl azides and benzoylated disaccharides by using TiCl4. Chemistry (Weinheim An Der Bergstrasse, Germany). 19: 14836-51. PMID 24591217 DOI: 10.1002/Chem.201302572 |
0.677 |
|
| 2013 |
Breen EP, Pilgrim W, Clarke KJ, Yssel C, Farrell M, Zhou J, Murphy PV, Porter RK. Lack of activation of UCP1 in isolated brown adipose tissue mitochondria by glucose-O-ω-modified saturated fatty acids of various chain lengths. Journal of Chemical Biology. 6: 121-33. PMID 24432128 DOI: 10.1007/S12154-013-0093-6 |
0.649 |
|
| 2013 |
Pilgrim W, O'Reilly C, Murphy PV. Synthesis of α-O- and α-S-glycosphingolipids related to Sphingomonous cell wall antigens using anomerisation. Molecules (Basel, Switzerland). 18: 11198-218. PMID 24036511 DOI: 10.3390/Molecules180911198 |
0.316 |
|
| 2013 |
Murphy PV, André S, Gabius HJ. The third dimension of reading the sugar code by lectins: design of glycoclusters with cyclic scaffolds as tools with the aim to define correlations between spatial presentation and activity. Molecules (Basel, Switzerland). 18: 4026-53. PMID 23558543 DOI: 10.3390/Molecules18044026 |
0.304 |
|
| 2012 |
Yan D, Naughton J, Clyne M, Murphy PV. Synthesis of bivalent glycoclusters containing GlcNAc as hexasaccharide mimetics. Bactericidal activity against Helicobacter pylori. Carbohydrate Research. 360: 1-7. PMID 22975273 DOI: 10.1016/J.Carres.2012.07.011 |
0.318 |
|
| 2012 |
Wang GN, André S, Gabius HJ, Murphy PV. Bi- to tetravalent glycoclusters: synthesis, structure-activity profiles as lectin inhibitors and impact of combining both valency and headgroup tailoring on selectivity. Organic & Biomolecular Chemistry. 10: 6893-907. PMID 22842468 DOI: 10.1039/C2Ob25870F |
0.378 |
|
| 2012 |
André S, Jarikote DV, Yan D, Vincenz L, Wang GN, Kaltner H, Murphy PV, Gabius HJ. Synthesis of bivalent lactosides and their activity as sensors for differences between lectins in inter- and intrafamily comparisons. Bioorganic & Medicinal Chemistry Letters. 22: 313-8. PMID 22142540 DOI: 10.1016/J.Bmcl.2011.11.010 |
0.32 |
|
| 2012 |
Napolitano C, Palwai VR, Eriksson LA, Murphy PV. Synthesis, kinase activity and molecular modeling of a resorcylic acid lactone incorporating an amide and a trans-enone in the macrocycle Tetrahedron. 68: 5533-5540. DOI: 10.1016/J.Tet.2012.04.082 |
0.389 |
|
| 2011 |
Zhou J, Matos MC, Murphy PV. Synthesis of a benzomacrolactone-based somatostatin mimetic. Organic Letters. 13: 5716-9. PMID 21988463 DOI: 10.1021/Ol202528K |
0.419 |
|
| 2011 |
O'Reilly C, Murphy PV. Synthesis of α-S-glycosphingolipids based on uronic acids. Organic Letters. 13: 5168-71. PMID 21875123 DOI: 10.1021/Ol202042H |
0.412 |
|
| 2011 |
Napolitano C, Natoni A, Santocanale C, Evensen L, Lorens JB, Murphy PV. Isosteric replacement of the Z-enone with haloethyl ketone and E-enone in a resorcylic acid lactone series and biological evaluation. Bioorganic & Medicinal Chemistry Letters. 21: 1167-70. PMID 21273066 DOI: 10.1016/J.Bmcl.2010.12.100 |
0.365 |
|
| 2011 |
Zhao Y, Liu M, Chagnault V, Wang J, Zhang X, Murphy PV. Biological study of a somatostatin mimetic based on the 1-deoxynojrimycin scaffold. Bioorganic & Medicinal Chemistry Letters. 21: 824-8. PMID 21194941 DOI: 10.1016/J.Bmcl.2010.11.088 |
0.301 |
|
| 2011 |
Brien CO, Murphy PV. Synthesis of 1-Deoxynojirimycin Derivatives from L-Sorbose via Wittig Reactions Journal of Carbohydrate Chemistry. 30: 626-640. DOI: 10.1080/07328303.2011.619287 |
0.371 |
|
| 2010 |
Napolitano C, McArdle P, Murphy PV. Access to resorcylic acid lactones via phosphonate based intramolecular olefination. The Journal of Organic Chemistry. 75: 7404-7. PMID 20939525 DOI: 10.1021/Jo100998B |
0.444 |
|
| 2010 |
Pilgrim W, Murphy PV. SnCl(4)- and TiCl(4)-catalyzed anomerization of acylated O- and S-glycosides: analysis of factors that lead to higher α:β anomer ratios and reaction rates. The Journal of Organic Chemistry. 75: 6747-55. PMID 20836488 DOI: 10.1021/Jo101090F |
0.363 |
|
| 2010 |
Zhao Y, Zhou Y, O' Boyle KM, Murphy PV. Biological study of the angiogenesis inhibitor N-(8-(3-ethynylphenoxy)octyl-1-deoxynojirimycin. Chemical Biology & Drug Design. 75: 570-7. PMID 20565474 DOI: 10.1111/J.1747-0285.2010.00968.X |
0.317 |
|
| 2010 |
Jarikote DV, O’Reilly C, Murphy PV. Ultrasound-assisted synthesis of C-glycosides Tetrahedron Letters. 51: 6776-6778. DOI: 10.1016/J.Tetlet.2010.10.113 |
0.32 |
|
| 2010 |
Zhou Y, Murphy PV. Synthesis of congeners of migrastatin and dorrigocin A from d-xylose Tetrahedron Letters. 51: 5262-5264. DOI: 10.1016/J.Tetlet.2010.07.141 |
0.404 |
|
| 2010 |
Jarikote DV, Murphy PV. Metathesis and Macrocycles with Embedded Carbohydrates European Journal of Organic Chemistry. 2010: 4959-4970. DOI: 10.1002/Ejoc.201000491 |
0.377 |
|
| 2009 |
Leyden R, Velasco-Torrijos T, André S, Gouin S, Gabius HJ, Murphy PV. Synthesis of bivalent lactosides based on terephthalamide, N,N'-diglucosylterephthalamide, and glycophane scaffolds and assessment of their inhibitory capacity on medically relevant lectins. The Journal of Organic Chemistry. 74: 9010-26. PMID 19899775 DOI: 10.1021/Jo901667R |
0.402 |
|
| 2009 |
André S, Velasco-Torrijos T, Leyden R, Gouin S, Tosin M, Murphy PV, Gabius HJ. Phenylenediamine-based bivalent glycocyclophanes: synthesis and analysis of the influence of scaffold rigidity and ligand spacing on lectin binding in cell systems with different glycomic profiles. Organic & Biomolecular Chemistry. 7: 4715-25. PMID 19865709 DOI: 10.1039/B913010A |
0.701 |
|
| 2009 |
Pilgrim W, Murphy PV. Alpha-glycosphingolipids via chelation-induced anomerization of O- and S-glucuronic and galacturonic acid derivatives. Organic Letters. 11: 939-42. PMID 19178158 DOI: 10.1021/Ol802915H |
0.329 |
|
| 2009 |
Rountree JSS, Murphy PV. Synthesis of a novel polyhydroxylated salicylic acid lactone framework Organic Letters. 11: 871-874. PMID 19170571 DOI: 10.1021/Ol802852R |
0.426 |
|
| 2009 |
Murphy P, Leyden R. Glycotriazolophane Synthesis via Click Chemistry Synlett. 2009: 1949-1950. DOI: 10.1055/S-0029-1217534 |
0.394 |
|
| 2009 |
O’Reilly C, O’Brien C, Murphy PV. Synthesis of a constrained polyfunctional bicyclic iminocyclitol scaffold from l-sorbose via a tandem sequence including stereoselective intramolecular Huisgen cycloaddition Tetrahedron Letters. 50: 4427-4429. DOI: 10.1016/J.Tetlet.2009.05.060 |
0.419 |
|
| 2008 |
Zhou Y, Murphy PV. New access to 1-deoxynojirimycin derivatives via azide-alkene cycloaddition. Organic Letters. 10: 3777-80. PMID 18672879 DOI: 10.1021/Ol8014495 |
0.393 |
|
| 2008 |
Doyle D, Murphy PV. Synthesis of novel glycophanes derived from glucuronic acid by ring closing alkene and alkyne metathesis. Carbohydrate Research. 343: 2535-44. PMID 18619584 DOI: 10.1016/J.Carres.2008.06.007 |
0.463 |
|
| 2008 |
Zhao Y, Zhou Y, O'Boyle KM, Murphy PV. Hybrids of 1-deoxynojirimycin and aryl-1,2,3-triazoles and biological studies related to angiogenesis. Bioorganic & Medicinal Chemistry. 16: 6333-7. PMID 18504133 DOI: 10.1016/J.Bmc.2008.05.012 |
0.332 |
|
| 2008 |
Chagnault V, Lalot J, Murphy PV. Synthesis of somatostatin mimetics based on 1-deoxynojirimycin. Chemmedchem. 3: 1071-6. PMID 18418832 DOI: 10.1002/Cmdc.200800038 |
0.307 |
|
| 2008 |
Zhou Y, Zhao Y, O' Boyle KM, Murphy PV. Hybrid angiogenesis inhibitors: synthesis and biological evaluation of bifunctional compounds based on 1-deoxynojirimycin and aryl-1,2,3-triazoles. Bioorganic & Medicinal Chemistry Letters. 18: 954-8. PMID 18166456 DOI: 10.1016/J.Bmcl.2007.12.034 |
0.368 |
|
| 2008 |
Anquetin G, Rawe SL, McMahon K, Murphy EP, Murphy PV. Synthesis of novel migrastatin and dorrigocin A analogues from D-glucal. Chemistry (Weinheim An Der Bergstrasse, Germany). 14: 1592-600. PMID 18038383 DOI: 10.1002/Chem.200701033 |
0.466 |
|
| 2008 |
Loukou C, Tosin M, Müller-Bunz H, Murphy PV. Corrigendum to “Synthesis of sugar-lactams from azides of glucuronic acid” Carbohydrate Research. 343: 412-413. DOI: 10.1016/J.Carres.2007.10.009 |
0.688 |
|
| 2008 |
Anquetin G, Horgan G, Rawe S, Murray D, Madden A, MacMathuna P, Doran P, Murphy PV. Synthesis of Novel Macrolactam and Macroketone Analogues of Migrastatin fromD-Glucal and Comparison with Macrolactone and Acyclic Analogues: A Dorrigocin A Congener Is a Potent Inhibitor of Gastric Cancer Cell Migration European Journal of Organic Chemistry. 2008: 1953-1958. DOI: 10.1002/Ejoc.200701192 |
0.371 |
|
| 2008 |
Chagnault V, Lalot J, Murphy P. Cover Picture: Synthesis of Somatostatin Mimetics Based on 1‐Deoxynojirimycin (ChemMedChem 7/2008) Chemmedchem. 3: 1009-1009. DOI: 10.1002/Cmdc.200890026 |
0.363 |
|
| 2007 |
Loukou C, Tosin M, Müller-Bunz H, Murphy PV. Synthesis of sugar-lactams from azides of glucuronic acid. Carbohydrate Research. 342: 1953-9. PMID 17477912 DOI: 10.1016/J.Carres.2007.04.003 |
0.72 |
|
| 2007 |
Matos MC, Murphy PV. Synthesis of macrolide-saccharide hybrids by ring-closing metathesis of precursors derived from glycitols and benzoic acids. The Journal of Organic Chemistry. 72: 1803-6. PMID 17274658 DOI: 10.1021/Jo062159L |
0.481 |
|
| 2007 |
Cronin L, Tosin M, Müller-Bunz H, Murphy PV. The synthesis of cyclic imidates from amides of glucuronic acid and investigation of glycosidation reactions. Carbohydrate Research. 342: 111-8. PMID 17123491 DOI: 10.1016/J.Carres.2006.10.023 |
0.723 |
|
| 2007 |
O'Brien C, Poláková M, Pitt N, Tosin M, Murphy PV. Glycosidation-anomerisation reactions of 6,1-anhydroglucopyranuronic acid and anomerisation of beta-D-glucopyranosiduronic acids promoted by SnCl(4). Chemistry (Weinheim An Der Bergstrasse, Germany). 13: 902-9. PMID 17086575 DOI: 10.1002/Chem.200601111 |
0.692 |
|
| 2007 |
Danieli E, Lalot J, Murphy PV. Selective protecting group manipulations on the 1-deoxynojirimycin scaffold Tetrahedron. 63: 6827-6834. DOI: 10.1016/J.Tet.2007.04.070 |
0.38 |
|
| 2007 |
Murphy PV. Peptidomimetics, Glycomimetics and Scaffolds from Carbohydrate Building Blocks Cheminform. 38. DOI: 10.1002/Ejoc.200700248 |
0.404 |
|
| 2006 |
Rawe SL, Doyle D, Zaric V, Rozas I, McMahon K, Tosin M, Bunz HM, Murphy EP, O' Boyle KM, Murphy PV. N-Glycosyl-thiophene-2-carboxamides: synthesis, structure and effects on the growth of diverse cell types. Carbohydrate Research. 341: 1370-90. PMID 16716276 DOI: 10.1016/J.Carres.2006.04.041 |
0.701 |
|
| 2006 |
Murphy PV, Rutledge PJ. Symbiosis in chemistry and biology. Nature Chemical Biology. 2: 59-62. PMID 16421580 DOI: 10.1038/Nchembio0206-59 |
0.32 |
|
| 2005 |
Gouin SG, Murphy PV. Synthesis of somatostatin mimetics based on the 1-deoxymannojirimycin scaffold. The Journal of Organic Chemistry. 70: 8527-32. PMID 16209603 DOI: 10.1021/Jo051454N |
0.368 |
|
| 2005 |
Cronin L, Murphy PV. Novel synthesis of castanospermine and 1-epicastanospermine. Organic Letters. 7: 2691-3. PMID 15957923 DOI: 10.1021/Ol0508577 |
0.363 |
|
| 2005 |
Gouin SG, Pilgrim W, Porter RK, Murphy PV. Synthesis of a glycolipid for studying mechanisms of mitochondrial uncoupling proteins Carbohydrate Research. 340: 1547-1552. PMID 15885669 DOI: 10.1016/J.Carres.2005.04.004 |
0.387 |
|
| 2005 |
Tosin M, Murphy PV. Synthesis of structurally defined scaffolds for bivalent ligand display based on glucuronic acid anilides. The degree of tertiary amide isomerism and folding depends on the configuration of a glycosyl azide. The Journal of Organic Chemistry. 70: 4107-17. PMID 15876103 DOI: 10.1021/Jo050200Z |
0.711 |
|
| 2005 |
Tosin M, O'Brien C, Fitzpatrick GM, Müller-Bunz H, Glass WK, Murphy PV. Synthesis and structural analysis of the anilides of glucuronic acid and orientation of the groups on the carbohydrate scaffolding. The Journal of Organic Chemistry. 70: 4096-106. PMID 15876102 DOI: 10.1021/Jo0501994 |
0.704 |
|
| 2005 |
Tosin M, Gouin SG, Murphy PV. Synthesis of structurally diverse and defined bivalent mannosides on saccharide scaffolding. Organic Letters. 7: 211-4. PMID 15646960 DOI: 10.1021/Ol047841L |
0.707 |
|
| 2005 |
Cronin L, Murphy PV. Synthesis of Castanospermine Synfacts. 2005: 285-285. DOI: 10.1055/S-2005-921590 |
0.381 |
|
| 2005 |
Killoran J, Gallagher JF, Murphy PV, O’Shea DF. A study of the effects of subunit pre-orientation for diarylpyrrole esters; design of new aryl-heteroaryl fluorescent sensors New Journal of Chemistry. 29: 1258. DOI: 10.1039/B507669B |
0.372 |
|
| 2005 |
Velasco-Torrijos T, Murphy PV. Synthesis and conformational analysis of novel water soluble macrocycles incorporating carbohydrates, including a β-cyclodextrin mimic Tetrahedron: Asymmetry. 16: 261-272. DOI: 10.1016/J.Tetasy.2004.11.020 |
0.364 |
|
| 2004 |
Velasco-Torrijos T, Murphy PV. Metathesis of structurally preorganized bivalent carbohydrates. Synthesis of macrocyclic and oligomeric scaffolds. Organic Letters. 6: 3961-4. PMID 15496074 DOI: 10.1021/Ol0484254 |
0.442 |
|
| 2004 |
McDonnell C, López O, Murphy P, Fernández Bolaños JG, Hazell R, Bols M. Conformational effects on glycoside reactivity: study of the high reactive conformer of glucose. Journal of the American Chemical Society. 126: 12374-85. PMID 15453771 DOI: 10.1021/Ja047476T |
0.324 |
|
| 2004 |
O'Brien A, Lynch C, O'Boyle KM, Murphy PV. Synthesis of disaccharides derived from heparin and evaluation of effects on endothelial cell growth and on binding of heparin to FGF-2. Carbohydrate Research. 339: 2343-54. PMID 15388349 DOI: 10.1016/J.Carres.2004.07.018 |
0.318 |
|
| 2004 |
Pitt N, Duane RM, O'Brien A, Bradley H, Wilson SJ, O'Boyle KM, Murphy PV. Synthesis of a glucuronic acid and glucose conjugate library and evaluation of effects on endothelial cell growth. Carbohydrate Research. 339: 1873-87. PMID 15261580 DOI: 10.1016/J.Carres.2004.05.024 |
0.309 |
|
| 2004 |
McDonnell C, Cronin L, O'Brien JL, Murphy PV. A general synthesis of iminosugars. The Journal of Organic Chemistry. 69: 3565-8. PMID 15132573 DOI: 10.1021/Jo035763U |
0.343 |
|
| 2004 |
Poláková M, Pitt N, Tosin M, Murphy PV. Glycosidation reactions of silyl ethers with conformationally inverted donors derived from glucuronic acid: stereoselective synthesis of glycosides and 2-deoxyglycosides. Angewandte Chemie (International Ed. in English). 43: 2518-21. PMID 15127440 DOI: 10.1002/Anie.200353196 |
0.722 |
|
| 2004 |
Tosin M, Müller-Bunz H, Murphy PV. Synthesis and X-ray single crystal structure of a bivalent glycocluster. Chemical Communications (Cambridge, England). 494-5. PMID 14973574 DOI: 10.1039/B313934D |
0.685 |
|
| 2004 |
Chery F, Murphy PV. Synthesis of an iminosugar based peptidomimetic analogue Tetrahedron Letters. 45: 2067-2069. DOI: 10.1016/J.Tetlet.2004.01.064 |
0.418 |
|
| 2004 |
Chery F, Cronin L, O'Brien JL, Murphy PV. Synthesis of peptidomimetics based on iminosugar and β-D- glucopyranoside scaffolds and inhibiton of HIV-protease Tetrahedron. 60: 6597-6608. DOI: 10.1016/J.Tet.2004.05.080 |
0.357 |
|
| 2003 |
Murphy PV, Bradley H, Tosin M, Pitt N, Fitzpatrick GM, Glass WK. Development of carbohydrate-based scaffolds for restricted presentation of recognition groups. Extension to divalent ligands and implications for the structure of dimerized receptors. The Journal of Organic Chemistry. 68: 5692-704. PMID 12839465 DOI: 10.1021/Jo034336D |
0.697 |
|
| 2003 |
Murphy PV, McDonnell C, Hämig L, Paterson DE, Taylor RJ. Confirmation of the structure of a glucono-1,4-lactone derivative obtained from silylation of glucono-1,5-lactone Tetrahedron: Asymmetry. 14: 79-85. DOI: 10.1016/S0957-4166(02)00747-4 |
0.56 |
|
| 2003 |
Murphy PV, O'Brien JL, Gorey-Feret LJ, Smith ABI. Synthesis of Novel HIV-1 Protease Inhibitors Based on Carbohydrate Scaffolds. Cheminform. 34. DOI: 10.1016/S0040-4020(03)00208-4 |
0.323 |
|
| 2002 |
Murphy PV, Pitt N, O'Brien A, Enright PM, Dunne A, Wilson SJ, Duane RM, O'Boyle KM. Identification of novel inhibitors of fibroblast growth factor (FGF-2) binding to heparin and endothelial cell survival from a structurally diverse carbohybrid library. Bioorganic & Medicinal Chemistry Letters. 12: 3287-90. PMID 12392734 DOI: 10.1016/S0960-894X(02)00700-X |
0.339 |
|
| 2002 |
Tosin M, Murphy PV. Synthesis of alpha-glucuronic acid and amide derivatives in the presence of a participating 2-acyl protecting group. Organic Letters. 4: 3675-8. PMID 12375916 DOI: 10.1021/Ol026629J |
0.705 |
|
| 2002 |
Murphy PV, O'Brien JL, Gorey-Feret LJ, Smith AB. Structure-based design and synthesis of HIV-1 protease inhibitors employing beta-D-mannopyranoside scaffolds. Bioorganic & Medicinal Chemistry Letters. 12: 1763-6. PMID 12067556 DOI: 10.1016/S0960-894X(02)00220-2 |
0.333 |
|
| 2002 |
Enright PM, Tosin M, Nieuwenhuyzen M, Cronin L, Murphy PV. A study of the epoxidation of 6-deoxyhex-5-enopyranosides. 1,5-Dicarbonyl derivatives and novel synthetic routes to D-xylo-hexos-5-ulose and D-lyxo-hexos-5-ulose. The Journal of Organic Chemistry. 67: 3733-41. PMID 12027687 DOI: 10.1021/Jo016378C |
0.713 |
|
| 2002 |
Griffin F, Paterson D, Murphy P, Taylor R. A New Route toexo-Glycals Using the Ramberg−Bäcklund Rearrangement European Journal of Organic Chemistry. 2002: 1305-1322. DOI: 10.1002/1099-0690(200204)2002:7<1305::Aid-Ejoc1305>3.0.Co;2-0 |
0.345 |
|
| 2001 |
O'Brien JL, Tosin M, Murphy PV. Novel synthesis of the glycosidase inhibitor deoxymannojirimycin and of a synthetic precursor D-lyxo-hexos-5-ulose. Organic Letters. 3: 3353-6. PMID 11594832 DOI: 10.1021/Ol016596S |
0.72 |
|
| 2001 |
Murphy PV, O'Brien JL, Smith AB. Stereospecific synthesis of beta-D-allopyranosides by dihydroxylation of beta-D-erythro-2,3-dideoxyhex-2-enopyranosides. Carbohydrate Research. 334: 327-35. PMID 11527535 DOI: 10.1016/S0008-6215(01)00181-1 |
0.334 |
|
| 2001 |
Bradley H, Fitzpatrick G, Glass WK, Kunz H, Murphy PV. Application of Ugi reactions in synthesis of divalent neoglycoconjugates: evidence that the sugars are presented in restricted conformation. Organic Letters. 3: 2629-32. PMID 11506595 DOI: 10.1021/Ol016294Q |
0.397 |
|
| 2001 |
Enright PM, O'Boyle KM, Murphy PV. Synthesis of D-hexos-5-uloses by novel in situ hydrolysis of epoxides derived from 6-deoxyhex-5-enopyranosides. Organic Letters. 2: 3929-32. PMID 11101456 DOI: 10.1021/Ol006714W |
0.451 |
|
| 2001 |
Enright PM, O'Boyle KM, Murphy PV. ChemInform Abstract: Synthesis of D-Hexos-5-uloses by Novel in situ Hydrolysis of Epoxides Derived from 6-Deoxyhex-5-enopyranosides. Cheminform. 32: no-no. DOI: 10.1002/CHIN.200115203 |
0.301 |
|
| 2000 |
Murphy PV, O’Sullivan TJ, Kennedy BD, Geraghty NWA. The reactions of diazo compounds with lactones. Part 2. The reaction of cyclic 2-diazo-1,3-dicarbonyl compounds with diketene: benzofuran formation Journal of the Chemical Society-Perkin Transactions 1. 2121-2126. DOI: 10.1039/B001394N |
0.368 |
|
| 2000 |
Murphy PV, O’Sullivan TJ, Geraghty NWA. The reactions of diazo compounds with lactones. Part 1. Cyclopropanespiro-β-lactones from diketene: synthesis and reactions Journal of the Chemical Society-Perkin Transactions 1. 2109-2119. DOI: 10.1039/B001393P |
0.327 |
|
| 1999 |
Murphy PV, Hubbard RE, Manallack DT, Wills RE, Montana JG, Taylor RJ. The design, synthesis, and evaluation of novel conformationally rigid analogues of sialyl Lewis(x). Bioorganic & Medicinal Chemistry. 6: 2421-39. PMID 9925299 DOI: 10.1016/S0968-0896(98)80017-5 |
0.447 |
|
| 1998 |
Griffin FK, Murphy PV, Paterson DE, Taylor RJ. A Ramberg-Bäcklund approach to exo-glycals Tetrahedron Letters. 39: 8179-8182. DOI: 10.1016/S0040-4039(98)01822-X |
0.501 |
|
| 1998 |
Murphy PV, Hubbard RE, Manallack DT, Montana JG, Taylor RJ. The synthesis of novel structural analogues of sialyl Lewisx Tetrahedron Letters. 39: 3273-3276. DOI: 10.1016/S0040-4039(98)00468-7 |
0.493 |
|
| 1997 |
Cunningham PD, Geraghty NWA, McArdle PJ, Murphy PV, O'Sullivan TJ. The reaction of cyclic 2-diazo-1,3-dicarbonyl compounds with β-and γ-lactones: formation of benzodioxepinones, benzodioxecinonesand benzofurans Journal of the Chemical Society-Perkin Transactions 1. 1-4. DOI: 10.1039/A604850A |
0.394 |
|
| 1996 |
Hubbard RE, Montana JG, Murphy PV, Taylor RJ. Glycosylation reactions of 2,3,4-tri-O-chlorosulfonyl-β-l-fucopyranosyl chloride and 2,3,4-tri-O-chlorosulfonyl-β-d-xylopyranosyl chloride Carbohydrate Research. 287: 247-253. DOI: 10.1016/0008-6215(96)00077-8 |
0.366 |
|
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