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Yang Luo - Publications

Affiliations: 
Genetics Brigham & Women's Hospital, Harvard Medical School, Boston, MA, United States 
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33 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Kang JB, Shen AZ, Gurajala S, Nathan A, Rumker L, Aguiar VRC, Valencia C, Lagattuta KA, Zhang F, Jonsson AH, Yazar S, Alquicira-Hernandez J, Khalili H, Ananthakrishnan AN, Jagadeesh K, ... ... Luo Y, et al. Mapping the dynamic genetic regulatory architecture of HLA genes at single-cell resolution. Nature Genetics. PMID 38036787 DOI: 10.1038/s41588-023-01586-6  0.52
2023 Sakaue S, Gurajala S, Curtis M, Luo Y, Choi W, Ishigaki K, Kang JB, Rumker L, Deutsch AJ, Schönherr S, Forer L, LeFaive J, Fuchsberger C, Han B, Lenz TL, et al. Tutorial: a statistical genetics guide to identifying HLA alleles driving complex disease. Nature Protocols. PMID 37495751 DOI: 10.1038/s41596-023-00853-4  0.496
2023 Suliman S, Nieto-Caballero VE, Asgari S, Lopez K, Iwany SK, Luo Y, Nathan A, Fernandez-Salinas D, Chiñas M, Huang CC, Zhang Z, León SR, Calderon RI, Lecca L, Murray M, et al. History of tuberculosis disease is associated with genetic regulatory variation in Peruvians. Medrxiv : the Preprint Server For Health Sciences. PMID 37425785 DOI: 10.1101/2023.06.20.23291558  0.485
2023 Barry A, McNulty MT, Jia X, Gupta Y, Debiec H, Luo Y, Nagano C, Horinouchi T, Jung S, Colucci M, Ahram DF, Mitrotti A, Sinha A, Teeninga N, Jin G, et al. Multi-population genome-wide association study implicates immune and non-immune factors in pediatric steroid-sensitive nephrotic syndrome. Nature Communications. 14: 2481. PMID 37120605 DOI: 10.1038/s41467-023-37985-w  0.518
2023 Kang JB, Shen AZ, Sakaue S, Luo Y, Gurajala S, Nathan A, Rumker L, Aguiar VRC, Valencia C, Lagattuta K, Zhang F, Jonsson AH, Yazar S, Alquicira-Hernandez J, Khalili H, et al. Mapping the dynamic genetic regulatory architecture of genes at single-cell resolution. Medrxiv : the Preprint Server For Health Sciences. PMID 36993194 DOI: 10.1101/2023.03.14.23287257  0.506
2022 Ishigaki K, Sakaue S, Terao C, Luo Y, Sonehara K, Yamaguchi K, Amariuta T, Too CL, Laufer VA, Scott IC, Viatte S, Takahashi M, Ohmura K, Murasawa A, Hashimoto M, et al. Multi-ancestry genome-wide association analyses identify novel genetic mechanisms in rheumatoid arthritis. Nature Genetics. PMID 36333501 DOI: 10.1038/s41588-022-01213-w  0.468
2022 Asgari S, Luo Y, Huang CC, Zhang Z, Calderon R, Jimenez J, Yataco R, Contreras C, Galea JT, Lecca L, Jones D, Moody DB, Murray MB, Raychaudhuri S. Higher native Peruvian genetic ancestry proportion is associated with tuberculosis progression risk. Cell Genomics. 2. PMID 35873671 DOI: 10.1016/j.xgen.2022.100151  0.453
2022 Nathan A, Asgari S, Ishigaki K, Valencia C, Amariuta T, Luo Y, Beynor JI, Baglaenko Y, Suliman S, Price AL, Lecca L, Murray MB, Moody DB, Raychaudhuri S. Single-cell eQTL models reveal dynamic T cell state dependence of disease loci. Nature. PMID 35545678 DOI: 10.1038/s41586-022-04713-1  0.468
2022 Ishigaki K, Lagattuta KA, Luo Y, James EA, Buckner JH, Raychaudhuri S. HLA autoimmune risk alleles restrict the hypervariable region of T cell receptors. Nature Genetics. PMID 35332318 DOI: 10.1038/s41588-022-01032-z  0.491
2021 Luo Y, Kanai M, Choi W, Li X, Sakaue S, Yamamoto K, Ogawa K, Gutierrez-Arcelus M, Gregersen PK, Stuart PE, Elder JT, Forer L, Schönherr S, Fuchsberger C, Smith AV, et al. Author Correction: A high-resolution HLA reference panel capturing global population diversity enables multi-ancestry fine-mapping in HIV host response. Nature Genetics. PMID 34728834 DOI: 10.1038/s41588-021-00979-9  0.417
2021 Luo Y, Kanai M, Choi W, Li X, Sakaue S, Yamamoto K, Ogawa K, Gutierrez-Arcelus M, Gregersen PK, Stuart PE, Elder JT, Forer L, Schönherr S, Fuchsberger C, Smith AV, et al. A high-resolution HLA reference panel capturing global population diversity enables multi-ancestry fine-mapping in HIV host response. Nature Genetics. 53: 1504-1516. PMID 34611364 DOI: 10.1038/s41588-021-00935-7  0.473
2021 Gamache I, Legault MA, Grenier JC, Sanchez R, Rhéaume E, Asgari S, Barhdadi A, Zada YF, Trochet H, Luo Y, Lecca L, Murray M, Raychaudhuri S, Tardif JC, Dubé MP, et al. A sex-specific evolutionary interaction between and . Elife. 10. PMID 34609279 DOI: 10.7554/eLife.69198  0.459
2021 Nathan A, Beynor JI, Baglaenko Y, Suliman S, Ishigaki K, Asgari S, Huang CC, Luo Y, Zhang Z, Lopez K, Lindestam Arlehamn CS, Ernst JD, Jimenez J, Calderón RI, Lecca L, et al. Multimodally profiling memory T cells from a tuberculosis cohort identifies cell state associations with demographics, environment and disease. Nature Immunology. PMID 34031617 DOI: 10.1038/s41590-021-00933-1  0.454
2021 Luo Y, Li X, Wang X, Gazal S, Mercader JM, Neale BM, Florez JC, Auton A, Price AL, Finucane HK, Raychaudhuri S. Estimating heritability and its enrichment in tissue-specific gene sets in admixed populations. Human Molecular Genetics. PMID 33987664 DOI: 10.1093/hmg/ddab130  0.438
2021 Cook S, Choi W, Lim H, Luo Y, Kim K, Jia X, Raychaudhuri S, Han B. Accurate imputation of human leukocyte antigens with CookHLA. Nature Communications. 12: 1264. PMID 33627654 DOI: 10.1038/s41467-021-21541-5  0.468
2021 Shi H, Gazal S, Kanai M, Koch EM, Schoech AP, Siewert KM, Kim SS, Luo Y, Amariuta T, Huang H, Okada Y, Raychaudhuri S, Sunyaev SR, Price AL. Population-specific causal disease effect sizes in functionally important regions impacted by selection. Nature Communications. 12: 1098. PMID 33597505 DOI: 10.1038/s41467-021-21286-1  0.477
2020 Krebs K, Bovijn J, Zheng N, Lepamets M, Censin JC, Jürgenson T, Särg D, Abner E, Laisk T, Luo Y, Skotte L, Geller F, Feenstra B, Wang W, Auton A, et al. Genome-wide Study Identifies Association between HLA-B55:01 and Self-Reported Penicillin Allergy. American Journal of Human Genetics. PMID 32888428 DOI: 10.1016/J.Ajhg.2020.08.008  0.505
2020 Choi W, Luo Y, Raychaudhuri S, Han B. HATK: HLA Analysis Toolkit. Bioinformatics (Oxford, England). PMID 32735319 DOI: 10.1093/Bioinformatics/Btaa684  0.516
2020 Asgari S, Luo Y, Akbari A, Belbin GM, Li X, Harris DN, Selig M, Bartell E, Calderon R, Slowikowski K, Contreras C, Yataco R, Galea JT, Jimenez J, Coit JM, et al. A positively selected FBN1 missense variant reduces height in Peruvian individuals. Nature. PMID 32499652 DOI: 10.1038/S41586-020-2302-0  0.52
2020 Gutierrez-Arcelus M, Baglaenko Y, Arora J, Hannes S, Luo Y, Amariuta T, Teslovich N, Rao DA, Ermann J, Jonsson AH, Navarrete C, Rich SS, Taylor KD, Rotter JI, et al. Allele-specific expression changes dynamically during T cell activation in HLA and other autoimmune loci. Nature Genetics. PMID 32066938 DOI: 10.1038/S41588-020-0579-4  0.557
2019 Amariuta T, Luo Y, Knevel R, Okada Y, Raychaudhuri S. Advances in genetics toward identifying pathogenic cell states of rheumatoid arthritis. Immunological Reviews. PMID 31782165 DOI: 10.1111/Imr.12827  0.533
2019 Luo Y, Suliman S, Asgari S, Amariuta T, Baglaenko Y, Martínez-Bonet M, Ishigaki K, Gutierrez-Arcelus M, Calderon R, Lecca L, León SR, Jimenez J, Yataco R, Contreras C, Galea JT, et al. Early progression to active tuberculosis is a highly heritable trait driven by 3q23 in Peruvians. Nature Communications. 10: 3765. PMID 31434886 DOI: 10.1038/S41467-019-11664-1  0.507
2019 Amariuta T, Luo Y, Gazal S, Davenport EE, van de Geijn B, Ishigaki K, Westra HJ, Teslovich N, Okada Y, Yamamoto K, Price AL, Raychaudhuri S. IMPACT: Genomic Annotation of Cell-State-Specific Regulatory Elements Inferred from the Epigenome of Bound Transcription Factors. American Journal of Human Genetics. PMID 31006511 DOI: 10.1016/J.Ajhg.2019.03.012  0.511
2018 Davenport EE, Amariuta T, Gutierrez-Arcelus M, Slowikowski K, Westra HJ, Luo Y, Shen C, Rao DA, Zhang Y, Pearson S, von Schack D, Beebe JS, Bing N, John S, Vincent MS, et al. Discovering in vivo cytokine-eQTL interactions from a lupus clinical trial. Genome Biology. 19: 168. PMID 30340504 DOI: 10.1186/S13059-018-1560-8  0.494
2018 Westra HJ, Martínez-Bonet M, Onengut-Gumuscu S, Lee A, Luo Y, Teslovich N, Worthington J, Martin J, Huizinga T, Klareskog L, Rantapaa-Dahlqvist S, Chen WM, Quinlan A, Todd JA, Eyre S, et al. Fine-mapping and functional studies highlight potential causal variants for rheumatoid arthritis and type 1 diabetes. Nature Genetics. PMID 30224649 DOI: 10.1038/S41588-018-0216-7  0.519
2017 Moutsianas L, De Lange K, Luo Y, Lee J, Jostins L, Lamb C, Kennedy N, Mansfield J, Parkes M, Barrett J, Anderson C. OP001 Whole genome sequencing and imputation in inflammatory bowel disease identifies 26 novel loci and offers therapeutically-relevant mechanistic insights. Journal of Crohn's & Colitis. 11: S1. PMID 28174916 DOI: 10.1093/Ecco-Jcc/Jjx002.000  0.306
2017 Luo Y, de Lange KM, Jostins L, Moutsianas L, Randall J, Kennedy NA, Lamb CA, McCarthy S, Ahmad T, Edwards C, Serra EG, Hart A, Hawkey C, Mansfield JC, Mowat C, et al. Exploring the genetic architecture of inflammatory bowel disease by whole-genome sequencing identifies association at ADCY7. Nature Genetics. PMID 28067910 DOI: 10.1038/Ng.3761  0.353
2017 de Lange KM, Moutsianas L, Lee JC, Lamb CA, Luo Y, Kennedy NA, Jostins L, Rice DL, Gutierrez-Achury J, Ji SG, Heap G, Nimmo ER, Edwards C, Henderson P, Mowat C, et al. Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease. Nature Genetics. PMID 28067908 DOI: 10.1038/Ng.3760  0.385
2016 Ni M, Chen C, Qian J, Xiao HX, Shi WF, Luo Y, Wang HY, Li Z, Wu J, Xu PS, Chen SH, Wong G, Bi Y, Xia ZP, Li W, et al. Intra-host dynamics of Ebola virus during 2014. Nature Microbiology. 1: 16151. PMID 27595345 DOI: 10.1038/Nmicrobiol.2016.151  0.304
2016 McCarthy S, Das S, Kretzschmar W, Delaneau O, Wood AR, Teumer A, Kang HM, Fuchsberger C, Danecek P, Sharp K, Luo Y, Sidore C, Kwong A, Timpson N, Koskinen S, et al. A reference panel of 64,976 haplotypes for genotype imputation. Nature Genetics. PMID 27548312 DOI: 10.1038/Ng.3643  0.334
2016 Rivas MA, Graham D, Sulem P, Stevens C, Desch AN, Goyette P, Gudbjartsson D, Jonsdottir I, Thorsteinsdottir U, Degenhardt F, Mucha S, Kurki MI, Li D, D'Amato M, Annese V, ... ... Luo Y, et al. A protein-truncating R179X variant in RNF186 confers protection against ulcerative colitis. Nature Communications. 7: 12342. PMID 27503255 DOI: 10.1038/Ncomms12342  0.319
2016 Sveinbjornsson G, Gudbjartsson DF, Halldorsson BV, Kristinsson KG, Gottfredsson M, Barrett JC, Gudmundsson LJ, Blondal K, Gylfason A, Gudjonsson SA, Helgadottir HT, Jonasdottir A, Jonasdottir A, Karason A, Kardum LB, ... ... Luo Y, et al. HLA class II sequence variants influence tuberculosis risk in populations of European ancestry. Nature Genetics. PMID 26829749 DOI: 10.1038/Ng.3498  0.352
2015 Curtis J, Luo Y, Zenner HL, Cuchet-Lourenço D, Wu C, Lo K, Maes M, Alisaac A, Stebbings E, Liu JZ, Kopanitsa L, Ignatyeva O, Balabanova Y, Nikolayevskyy V, Baessmann I, et al. Susceptibility to tuberculosis is associated with variants in the ASAP1 gene encoding a regulator of dendritic cell migration. Nature Genetics. 47: 523-7. PMID 25774636 DOI: 10.1038/Ng.3248  0.34
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