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Xinying Yang - Publications

Affiliations: 
2005-2006 Chemistry Georgia State University, Atlanta, GA, United States 
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23 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Zhao Y, Yao Z, Ren W, Yang X, Hou X, Cao S, Fang H. Design, synthesis and bioactivity evaluations of 8-substituted-quinoline-2-carboxamide derivatives as novel histone deacetylase (HDAC) inhibitors. Bioorganic & Medicinal Chemistry. 85: 117242. PMID 37079967 DOI: 10.1016/j.bmc.2023.117242  0.317
2022 Liang H, Zhu Y, Zhao Z, Du J, Yang X, Fang H, Hou X. Structure-Based Design of 2-Aminopurine Derivatives as CDK2 Inhibitors for Triple-Negative Breast Cancer. Frontiers in Pharmacology. 13: 864342. PMID 35592410 DOI: 10.3389/fphar.2022.864342  0.313
2022 Liang X, Li X, Zhao Z, Nie Y, Yao Z, Ren W, Yang X, Hou X, Fang H. Design, synthesis and biological evaluation of hydantoin derivatives as Mcl-1 selective inhibitors. Bioorganic Chemistry. 121: 105643. PMID 35150958 DOI: 10.1016/j.bioorg.2022.105643  0.326
2021 Liang T, Xue J, Yao Z, Ye Y, Yang X, Hou X, Fang H. Design, synthesis and biological evaluation of 3, 4-disubstituted-imidazolidine-2, 5-dione derivatives as HDAC6 selective inhibitors. European Journal of Medicinal Chemistry. 221: 113526. PMID 33992929 DOI: 10.1016/j.ejmech.2021.113526  0.343
2020 Zhou Y, Liu X, Xue J, Liu L, Liang T, Li W, Yang X, Hou X, Fang H. Discovery of Peptide Boronate Derivatives as Histone Deacetylase (HDAC) and Proteasome Dual Inhibitors for Overcoming Bortezomib Resistance of Multiple Myeloma. Journal of Medicinal Chemistry. PMID 32267687 DOI: 10.1021/Acs.Jmedchem.9B02161  0.316
2020 Liu L, Liu R, Yang X, Hou X, Fang H. Design, synthesis and biological evaluation of tyrosine derivatives as Mcl-1 inhibitors. European Journal of Medicinal Chemistry. 191: 112142. PMID 32088497 DOI: 10.1016/J.Ejmech.2020.112142  0.437
2019 Chen C, Yang X, Fang H, Hou X. Design, synthesis and preliminary bioactivity evaluations of 8-hydroxyquinoline derivatives as matrix metalloproteinase (MMP) inhibitors. European Journal of Medicinal Chemistry. 181: 111563. PMID 31415980 DOI: 10.1016/J.Ejmech.2019.111563  0.312
2019 Liang T, Hou X, Zhou Y, Yang X, Fang H. Design, Synthesis, and Biological Evaluation of 2,4-Imidazolinedione Derivatives as HDAC6 Isoform-Selective Inhibitors. Acs Medicinal Chemistry Letters. 10: 1122-1127. PMID 31413795 DOI: 10.1021/Acsmedchemlett.9B00084  0.414
2019 Chen C, Nie Y, Xu G, Yang X, Fang H, Hou X. Design, synthesis and preliminary bioactivity studies of indomethacin derivatives as Bcl-2/Mcl-1 dual inhibitors. Bioorganic & Medicinal Chemistry. PMID 31079964 DOI: 10.1016/J.Bmc.2019.05.003  0.386
2019 Liu R, Liu L, Yang X, Fang H. Discovery and development of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid derivatives as Bcl-2/Mcl-1 inhibitors. Bioorganic Chemistry. 88: 102938. PMID 31028992 DOI: 10.1016/J.Bioorg.2019.102938  0.429
2019 Li Y, Fang H, Hou Z, Sang L, Yang X. An in-line capillary electrophoresis assay for the high-throughput screening of histone deacetylase inhibitors. Journal of Chromatography. A. PMID 30665742 DOI: 10.1016/J.Chroma.2019.01.025  0.328
2018 Liu R, Liu L, Liu T, Yang X, Wan Y, Fang H. Discovery and development of substituted tyrosine derivatives as Bcl-2/Mcl-1 inhibitors. Bioorganic & Medicinal Chemistry. PMID 30170927 DOI: 10.1016/J.Bmc.2018.08.030  0.393
2017 Xu G, Liu T, Zhou Y, Yang X, Fang H. 1-Phenyl-1H-indole derivatives as a new class of Bcl-2/Mcl-1 dual inhibitors: Design, synthesis, and preliminary biological evaluation. Bioorganic & Medicinal Chemistry. PMID 28866374 DOI: 10.1016/J.Bmc.2017.08.024  0.407
2017 Su R, Hou Z, Sang L, Zhou ZM, Fang H, Yang X. Enantioseparation of angiotensin II receptor type 1 blockers: evaluation of 6-substituted carbamoyl benzimidazoles on immobilized polysaccharide-based chiral stationary phases. Unusual temperature behavior. Journal of Chromatography. A. PMID 28784322 DOI: 10.1016/J.Chroma.2017.07.081  0.312
2017 Zhou Y, Dun Y, Fu H, Wang L, Pan X, Yang X, Fang H. Design, synthesis and preliminary bioactivity evaluation of N-benzylpyrimidin-2-amine derivatives as novel histone deacetylase (HDAC) inhibitor. Chemical Biology & Drug Design. PMID 28489276 DOI: 10.1111/Cbdd.13019  0.405
2017 Chen C, Hou X, Wang G, Pan W, Yang X, Zhang Y, Fang H. Design, synthesis and biological evaluation of quinoline derivatives as HDAC class I inhibitors. European Journal of Medicinal Chemistry. 133: 11-23. PMID 28371677 DOI: 10.1016/J.Ejmech.2017.03.064  0.403
2015 Fu H, Hou X, Wang L, Dun Y, Yang X, Fang H. Design, synthesis and biological evaluation of 3-aryl-rhodanine benzoic acids as anti-apoptotic protein Bcl-2 inhibitors. Bioorganic & Medicinal Chemistry Letters. PMID 26421995 DOI: 10.1016/J.Bmcl.2015.09.051  0.411
2015 Yan Y, Chen X, Yang X, Zhang J, Xu W, Zhang Y. Synthesis of chiral ND-322, ND-364 and ND-364 derivatives as selective inhibitors of human gelatinase. Bioorganic & Medicinal Chemistry. PMID 26386821 DOI: 10.1016/J.Bmc.2015.09.013  0.358
2015 Wan Y, Wu S, Xiao G, Liu T, Hou X, Chen C, Guan P, Yang X, Fang H. Design, synthesis and preliminary bioactivity studies of 2-thioxo-4-thiazolidinone derivatives as Bcl-2 inhibitors. Bioorganic & Medicinal Chemistry. 23: 1994-2003. PMID 25818766 DOI: 10.1016/J.Bmc.2015.03.024  0.41
2014 Chen D, Shen A, Li J, Shi F, Chen W, Ren J, Liu H, Xu Y, Wang X, Yang X, Sun Y, Yang M, He J, Wang Y, Zhang L, et al. Discovery of potent N-(isoxazol-5-yl)amides as HSP90 inhibitors. European Journal of Medicinal Chemistry. 87: 765-81. PMID 25313505 DOI: 10.1016/j.ejmech.2014.09.065  0.303
2014 Yang X, Su L, Hou X, Ding S, Xu W, Wang B, Fang H. High-performance liquid chromatographic enantioseparation of 3,5-disubstituted hydantoins analogs and temperature-induced reversals of elution orders on a polysaccharide-based chiral stationary phase. Journal of Chromatography. A. 1355: 291-5. PMID 24973033 DOI: 10.1016/J.Chroma.2014.06.022  0.459
2012 Yang X, Hou X, Wang B, Li M, Fang H. Density functional theory based quantitative structure-property relationship studies on coumarin-based prodrugs. Bioscience Trends. 6: 234-40. PMID 23229116 DOI: 10.5582/Bst.2012.V6.5.234  0.427
2012 Wu Z, Yang X, Xu W, Wang B, Fang H. A new boronic acid-based fluorescent sensor for L-dihydroxyphenylalanine. Drug Discoveries and Therapeutics. 6: 238-241. DOI: 10.5582/Ddt.2012.V6.5.238  0.425
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