| Year |
Citation |
Score |
| 2024 |
Laible E, Wegner A, Knutson K, Kacmaz H, Garramone GK, Gogineni K, Matveyenko A, Linden DR, Farrugia G, Beyder A. Circadian rhythm and whole gut transit in mice. Neurogastroenterology and Motility. e14771. PMID 38396340 DOI: 10.1111/nmo.14771 |
0.519 |
|
| 2024 |
Niloy SI, Strege PR, Hannan EC, Cowan LM, Linsenmeier F, Friedrich O, Farrugia G, Beyder A. Stretch response of the mechano-gated channel TMEM63A in membrane patches and single cells. American Journal of Physiology. Cell Physiology. PMID 38189136 DOI: 10.1152/ajpcell.00583.2023 |
0.607 |
|
| 2023 |
Strege PR, Cowan LM, Alcaino C, Mazzone A, Ahern CA, Milescu LS, Farrugia G, Beyder A. Mechanosensitive pore opening of a prokaryotic voltage-gated sodium channel. Elife. 12. PMID 36912788 DOI: 10.7554/eLife.79271 |
0.802 |
|
| 2022 |
Knutson KR, Whiteman ST, Alcaino C, Mercado-Perez A, Finholm I, Serlin HK, Bellampalli SS, Linden DR, Farrugia G, Beyder A. Intestinal enteroendocrine cells rely on ryanodine and IP calcium store receptors for mechanotransduction. The Journal of Physiology. PMID 36428286 DOI: 10.1113/JP283383 |
0.766 |
|
| 2022 |
Aghababaie Z, O'Grady G, Nisbet LA, Modesto AE, Chan CA, Matthee A, Amirapu S, Beyder A, Farrugia G, Asirvatham SJ, Sands GB, Paskaranandavadivel N, Cheng LK, Angeli-Gordon TR. Localized bioelectrical conduction block from radiofrequency gastric ablation persists post-healing: safety and feasibility in a recovery model. American Journal of Physiology. Gastrointestinal and Liver Physiology. PMID 36255716 DOI: 10.1152/ajpgi.00116.2022 |
0.543 |
|
| 2022 |
Cowan LM, Strege PR, Rusinova R, Andersen OS, Farrugia G, Beyder A. Capsaicin as an amphipathic modulator of Na1.5 mechanosensitivity. Channels (Austin, Tex.). 16: 9-26. PMID 35412435 DOI: 10.1080/19336950.2022.2026015 |
0.577 |
|
| 2022 |
Aghababaie Z, Cheng LK, Paskaranandavadivel N, Avci R, Chan CA, Matthee A, Amirapu S, Asirvatham SJ, Farrugia G, Beyder A, O'Grady G, Angeli-Gordon TR. Targeted ablation of gastric pacemaker sites to modulate patterns of bioelectrical slow wave activation and propagation, in an anesthetized pig model. American Journal of Physiology. Gastrointestinal and Liver Physiology. PMID 35137624 DOI: 10.1152/ajpgi.00332.2021 |
0.551 |
|
| 2021 |
Treichel AJ, Finholm I, Knutson KR, Alcaino C, Whiteman ST, Brown MR, Matveyenko A, Wegner A, Kacmaz H, Mercado-Perez A, Gajdos GB, Ordog T, Grover M, Szurzewski J, Linden DR, ... Farrugia G, et al. Specialized mechanosensory epithelial cells in mouse gut intrinsic tactile sensitivity. Gastroenterology. PMID 34688712 DOI: 10.1053/j.gastro.2021.10.026 |
0.785 |
|
| 2021 |
Zheng T, Ellinghaus D, Juzenas S, Cossais F, Burmeister G, Mayr G, Jørgensen IF, Teder-Laving M, Skogholt AH, Chen S, Strege PR, Ito G, Banasik K, Becker T, Bokelmann F, ... ... Farrugia G, et al. Genome-wide analysis of 944 133 individuals provides insights into the etiology of haemorrhoidal disease. Gut. PMID 33888516 DOI: 10.1136/gutjnl-2020-323868 |
0.502 |
|
| 2021 |
Joshi V, Strege PR, Farrugia G, Beyder A. Mechanotransduction in gastrointestinal smooth muscle cells: Role of mechanosensitive ion channels. American Journal of Physiology. Gastrointestinal and Liver Physiology. PMID 33729004 DOI: 10.1152/ajpgi.00481.2020 |
0.62 |
|
| 2021 |
Aghababaie Z, Paskaranandavadivel N, Amirapu S, Chan CA, Du P, Asirvatham S, Farrugia G, Beyder A, O'Grady G, Cheng LK, Angeli-Gordon TR. Gastric Ablation as a Novel Technique for Modulating Electrical Conduction in the in-vivo Stomach. American Journal of Physiology. Gastrointestinal and Liver Physiology. PMID 33470186 DOI: 10.1152/ajpgi.00448.2020 |
0.56 |
|
| 2020 |
Kacmaz H, Alto A, Knutson K, Linden DR, Gibbons SJ, Farrugia G, Beyder A. A simple automated approach to measure mouse whole gut transit. Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society. e13994. PMID 33000540 DOI: 10.1111/nmo.13994 |
0.54 |
|
| 2020 |
Knutson KR, Finholm I, Treichel AJ, Whiteman S, Linden DR, Grover M, Farrugia G, Beyder A. Epithelial Mechanosensitive Ion Channel Piezo2 Contributes to Pressure‐Induced Epithelial Chloride Secretion in Mouse Colon The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.04209 |
0.641 |
|
| 2020 |
Strege PR, Alcaino C, Ahern CA, Farrugia G, Beyder A. Tu1195 ELUCIDATION OF THE MECHANISMS BY WHICH STRETCH ALTERS SODIUM CHANNEL FUNCTION THROUGH USE OF A MUTATED BACTERIAL CHANNEL Gastroenterology. 158: S-1014. DOI: 10.1016/S0016-5085(20)33206-6 |
0.79 |
|
| 2020 |
Knutson KR, Finholm IW, Treichel AJ, Whiteman S, Linden DR, Grover M, Farrugia G, Beyder A. Su1225 PRESSURE-INDUCED EPITHELIAL ION TRANSPORT OF THE MURINE GASTROINTESTINAL EPITHELIUM IS DEPENDENT ON CHLORIDE SECRETION AND THE MECHANOSENSTITIVE ION CHANNEL PIEZO2. Gastroenterology. 158: S-550. DOI: 10.1016/S0016-5085(20)32073-4 |
0.612 |
|
| 2019 |
Du P, Mazzone A, Calder S, Qian A, Gibbons SJ, Farrugia G, Beyder A. A Method for Multi-day Tracking of Gastrointestinal Smooth Muscle Contractile Patterns in Organotypic Culture. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 2019: 4791-4794. PMID 31946933 DOI: 10.1109/EMBC.2019.8857365 |
0.552 |
|
| 2019 |
Aghababaie Z, Chan CA, Paskaranandavadivel N, Beyder A, Farrugia G, Asirvatham S, O'Grady G, Cheng LK, Angeli TR. Feasibility of High-Resolution Electrical Mapping for Characterizing Conduction Blocks Created by Gastric Ablation. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 2019: 170-173. PMID 31945871 DOI: 10.1109/EMBC.2019.8856406 |
0.555 |
|
| 2019 |
Mazzone A, Strege PR, Gibbons SJ, Alcaino C, Joshi V, Haak AJ, Tschumperlin DJ, Bernard CE, Cima RR, Larson DW, Chua HK, Graham RP, El Refaey M, Mohler PJ, Hayashi Y, ... ... Farrugia G, et al. microRNA overexpression in slow transit constipation leads to reduced Na1.5 current and altered smooth muscle contractility. Gut. PMID 31757880 DOI: 10.1136/Gutjnl-2019-318747 |
0.766 |
|
| 2019 |
DeSimone CV, McLeod CJ, Gomez Pinilla PJ, Beyder A, Farrugia G, Asirvatham SJ, Kapa S. Telocytes express ANO-1-encoded chloride channels in canine ventricular myocardium. Journal of Arrhythmia. 35: 515-521. PMID 31293701 DOI: 10.1002/Joa3.12176 |
0.621 |
|
| 2019 |
Strege PR, Mercado-Perez A, Mazzone A, Saito YA, Bernard CE, Farrugia G, Beyder A. mutation G615E results in Na1.5 voltage-gated sodium channels with normal voltage-dependent function yet loss of mechanosensitivity. Channels (Austin, Tex.). 13: 287-298. PMID 31262209 DOI: 10.1080/19336950.2019.1632670 |
0.649 |
|
| 2019 |
Alcaino C, Knutson KR, Nayak V, Strege PR, Kacmaz H, Treichel AJ, Li J, Leiter AB, Farrugia G, Beyder A. 1013 – Exploring the Roles of Voltage-Gated Calcium Channels in Mouse Enteroendocrine Cell Mechanotransduction Gastroenterology. 156: S-220. DOI: 10.1016/S0016-5085(19)37345-7 |
0.795 |
|
| 2019 |
Mazzone A, Strege PR, Alcaino C, Haak AJ, Tschumperlin DJ, Refaey ME, Mohler PJ, Hayashi Y, Ordog T, Calder SS, Du P, Gibbons SJ, Farrugia G, Beyder A. 788 – Microrna Let-7F is Overexpressed in Colonic Smooth Muscle from Patients with Slow Transit Constipation, Reduces Voltage-Gated Sodium Channel Nav1.5 Current Density and Gastrointestinal Smooth Muscle Contractility Gastroenterology. 156: S-165. DOI: 10.1016/S0016-5085(19)37205-1 |
0.791 |
|
| 2018 |
Knutson K, Strege PR, Li J, Leiter AB, Farrugia G, Beyder A. Whole Cell Electrophysiology of Primary Cultured Murine Enterochromaffin Cells. Journal of Visualized Experiments : Jove. PMID 30320764 DOI: 10.3791/58112 |
0.608 |
|
| 2018 |
Alcaino C, Knutson KR, Treichel AJ, Yildiz G, Strege PR, Linden DR, Li JH, Leiter AB, Szurszewski JH, Farrugia G, Beyder A. A population of gut epithelial enterochromaffin cells is mechanosensitive and requires Piezo2 to convert force into serotonin release. Proceedings of the National Academy of Sciences of the United States of America. PMID 30037999 DOI: 10.1073/Pnas.1804938115 |
0.802 |
|
| 2018 |
Treichel AJ, Farrugia G, Beyder A. The touchy business of gastrointestinal (GI) mechanosensitivity. Brain Research. 1693: 197-200. PMID 29903622 DOI: 10.1016/J.Brainres.2018.02.039 |
0.615 |
|
| 2018 |
Strege PR, Mazzone A, Loftus YAS, Bernard C, Gibbons SJ, Linden DR, Chang L, Beyder A, Farrugia G. Tu1268 - IBS-Associated Scn5A Mutation G615E Results in Nav1.5 Voltage-Dependent Sodium Channels with Normal Voltage-Dependent Function and Loss of Mechanosensitivity Gastroenterology. 154: S-920. DOI: 10.1016/S0016-5085(18)33094-4 |
0.629 |
|
| 2018 |
Ayala CAA, Knutson KR, Yildiz G, Linden DR, Li J, Leiter AB, Farrugia G, Beyder A. Mo1594 - The Role of Piezo2 Mechanosensitive Ion Channel in Enterochromaffin (EC) Cell Mechanosensitivity Gastroenterology. 154: S-764. DOI: 10.1016/S0016-5085(18)32645-3 |
0.634 |
|
| 2017 |
Strege PR, Mazzone A, Bernard CE, Neshatian L, Gibbons SJ, Saito YA, Tester DJ, Calvert ML, Mayer EA, Chang L, Ackerman MJ, Beyder A, Farrugia G. Irritable bowel syndrome (IBS) patients have SCN5A channelopathies that lead to decreased NaV1.5 current and mechanosensitivity. American Journal of Physiology. Gastrointestinal and Liver Physiology. ajpgi.00016.2017. PMID 29167113 DOI: 10.1152/Ajpgi.00016.2017 |
0.633 |
|
| 2017 |
Strege PR, Knutson K, Eggers SJ, Li JH, Wang F, Linden D, Szurszewski JH, Milescu L, Leiter AB, Farrugia G, Beyder A. Sodium channel NaV1.3 is important for enterochromaffin cell excitability and serotonin release. Scientific Reports. 7: 15650. PMID 29142310 DOI: 10.1038/S41598-017-15834-3 |
0.648 |
|
| 2017 |
Saravanaperumal SA, Gibbons SJ, Malysz J, Sha L, Linden DR, Szurszewski JH, Farrugia G. Extracellular Cl(-) regulates electrical slow waves and setting of smooth muscle membrane potential by interstitial cells of Cajal in mouse jejunum. Experimental Physiology. PMID 28971566 DOI: 10.1113/Ep086367 |
0.316 |
|
| 2017 |
Alcaino C, Farrugia G, Beyder A. Mechanosensitive Piezo Channels in the Gastrointestinal Tract. Current Topics in Membranes. 79: 219-244. PMID 28728818 DOI: 10.1016/Bs.Ctm.2016.11.003 |
0.81 |
|
| 2017 |
Bhattarai Y, Schmidt BA, Linden DR, Larson ED, Grover M, Beyder A, Farrugia G, Kashyap PC. Human Derived Gut Microbiota Modulates Colonic Secretion in Mice by Regulating 5-HT3 Receptor Expression via Acetate Production. American Journal of Physiology. Gastrointestinal and Liver Physiology. ajpgi.00448.2016. PMID 28408644 DOI: 10.1152/Ajpgi.00448.2016 |
0.579 |
|
| 2017 |
Strege PR, Gibbons SJ, Mazzone A, Bernard CE, Beyder A, Farrugia G. EAVK "segment c" sequence confers Ca(2+)-dependent changes to the kinetics of full length human Ano1. American Journal of Physiology. Gastrointestinal and Liver Physiology. ajpgi.00429.2016. PMID 28336549 DOI: 10.1152/Ajpgi.00429.2016 |
0.616 |
|
| 2017 |
Alcaino C, Knutson K, Gottlieb PA, Farrugia G, Beyder A. Mechanosensitive ion channel Piezo2 is inhibited by D-GsMTx4. Channels (Austin, Tex.). 0. PMID 28085630 DOI: 10.1080/19336950.2017.1279370 |
0.801 |
|
| 2017 |
Strege PR, Gibbons SJ, Mazzone A, Bernard C, Beyder A, Farrugia G. EAVK and Segment C†Sequence Confers CA 2+ -Dependent Changes to the Kinetics of Full Length Human ANO1 Gastroenterology. 152: S930. DOI: 10.1016/S0016-5085(17)33171-2 |
0.562 |
|
| 2017 |
Strege PR, Knutson KR, Eggers S, Wang F, Li HJ, Leiter AB, Farrugia G, Beyder A. SCN3A-Encoded Voltage-Gated Sodium Channel NaV1.3 Bestows Mouse Enterochromaffin Cells with Patterns of Bursting Electrical Activity Gastroenterology. 152: S710. DOI: 10.1016/S0016-5085(17)32477-0 |
0.646 |
|
| 2017 |
Castaneda D, Wang F, Treichel AJ, Streyle M, Knutson KR, Bernard C, Li HJ, Leiter AB, Farrugia G, Beyder A. Mechanosensitive ION Channel Piezo2 Distribution in Mouse Small Bowel and Colon Enterochromaffin Cells Gastroenterology. 152: S180. DOI: 10.1016/S0016-5085(17)30916-2 |
0.639 |
|
| 2016 |
Malysz J, Gibbons SJ, Saravanaperumal SA, Du P, Eisenman ST, Cao C, Oh U, Saur D, Klein S, Ordog T, Farrugia G. Conditional genetic deletion of Ano1 in interstitial cells of Cajal impairs Ca2+ transients and slow-waves in adult mouse small intestine. American Journal of Physiology. Gastrointestinal and Liver Physiology. ajpgi.00363.2016. PMID 27979828 DOI: 10.1152/Ajpgi.00363.2016 |
0.301 |
|
| 2016 |
Henström M, Hadizadeh F, Beyder A, Bonfiglio F, Zheng T, Assadi G, Rafter J, Bujanda L, Agreus L, Andreasson A, Dlugosz A, Lindberg G, Schmidt PT, Karling P, Ohlsson B, ... ... Farrugia G, et al. TRPM8 polymorphisms associated with increased risk of IBS-C and IBS-M. Gut. PMID 27974553 DOI: 10.1136/Gutjnl-2016-313346 |
0.639 |
|
| 2016 |
Choi KM, Gibbons SJ, Sha L, Beyder A, Verhulst PJ, Cipriani G, Phillips JE, Bauer AJ, Ordog T, Camp JJ, Ge X, Bharucha AE, Linden DR, Szurszewski JH, Kashyap PC, ... Farrugia G, et al. Interleukin 10 Restores Gastric Emptying, Electrical Activity, and Interstitial Cells of Cajal Networks in Diabetic Mice. Cellular and Molecular Gastroenterology and Hepatology. 2: 454-467. PMID 27795979 DOI: 10.1016/J.Jcmgh.2016.04.006 |
0.593 |
|
| 2016 |
Beyder A, Farrugia G. Ion channelopathies in functional GI disorders. American Journal of Physiology. Gastrointestinal and Liver Physiology. ajpgi.00237.2016. PMID 27514480 DOI: 10.1152/Ajpgi.00237.2016 |
0.636 |
|
| 2016 |
Wang F, Knutson K, Alcaino C, Linden DR, Gibbons SJ, Kashyap P, Grover M, Oeckler R, Gottlieb PA, Li HJ, Leiter AB, Farrugia G, Beyder A. Mechanosensitive ion channel Piezo2 is important for enterochromaffin cell response to mechanical forces. The Journal of Physiology. PMID 27392819 DOI: 10.1113/Jp272718 |
0.79 |
|
| 2016 |
Rajan E, Gostout CJ, Wong Kee Song LM, Szarka LA, Kashyap PC, Smyrk TC, Bingener J, Deters JL, Knipschield MA, Bernard CE, Farrugia G. Innovative gastric endoscopic muscle biopsy to identify all cell types, including myenteric neurons and interstitial cells of Cajal in patients with idiopathic gastroparesis: a feasibility study (with video). Gastrointestinal Endoscopy. PMID 27129395 DOI: 10.1016/J.Gie.2016.04.029 |
0.333 |
|
| 2016 |
Cipriani G, Gibbons SJ, Verhulst PJ, Choi KM, Eisenman ST, Hein SS, Ordog T, Linden DR, Szurszewski JH, Farrugia G. Diabetic Csf1(op/op) mice lacking macrophages are protected against the development of delayed gastric emptying. Cellular and Molecular Gastroenterology and Hepatology. 2: 40-47. PMID 26771000 DOI: 10.1016/J.Jcmgh.2015.09.001 |
0.313 |
|
| 2016 |
Knutson K, Wang F, Alcaino C, Bernard C, Farrugia G, Beyder A. The mechanosensitive ion channel Piezo2 is selectively expressed in enterochromaffin (EC) cells of the human and mouse gastrointestinal mucosa The Faseb Journal. 30. DOI: 10.1096/Fasebj.30.1_Supplement.1254.5 |
0.797 |
|
| 2016 |
Alcaino CA, Strege PR, Bernard CE, Farrugia G, Beyder A. Mechanosensitivity of the Bacterial Voltage-Gated Sodium Channel NaChBac Biophysical Journal. 110: 110a. DOI: 10.1016/S0016-5085(17)30845-4 |
0.804 |
|
| 2016 |
Strege PR, Beyder A, Mazzone A, Bernard C, Linden DR, Gibbons SJ, Chang L, Mayer EA, Farrugia G. Tu1803 IBS-Associated SCN5A Mutation G615E Results in a NaV1.5 Channel With Normal Na+ Current Density but Loss of Mechanosensitivity Gastroenterology. 150: S952. DOI: 10.1016/S0016-5085(16)33214-0 |
0.618 |
|
| 2016 |
Angeli TR, Quesada MJH, Du P, Paskaranandavadivel N, Amirapu S, Beyder A, Asirvatham SJ, Farrugia G, Cheng LK, O'Grady G. Mo1587 Gastric Ablation As a Novel Therapeutic Technique for Modulating Gastric Slow Wave Activity Gastroenterology. 150: S721. DOI: 10.1016/S0016-5085(16)32458-1 |
0.581 |
|
| 2016 |
Strege PR, Knutson KR, Kashyap PC, Li HJ, Leiter AB, Farrugia G, Beyder A. 181 Mouse Colon Enterochromaffin (EC) Cells Express Voltage-Gated Sodium Channels and Are Electrically Excitable Gastroenterology. 150: S47. DOI: 10.1016/S0016-5085(16)30282-7 |
0.653 |
|
| 2016 |
Wang F, Ayala CAA, Knutson KR, Grover M, Bernard C, Linden DR, Kashyap PC, Li HJ, Leiter AB, Farrugia G, Beyder A. 179 Mechanosensitive Ion Channel Piezo2 in Mouse Enterochromaffin Cells Is Important for Pressure-Induced Secretion From Small Bowel Mucosa Gastroenterology. 150: S46. DOI: 10.1016/S0016-5085(16)30280-3 |
0.639 |
|
| 2016 |
Mazzone A, Strege PR, Bernard C, Cima RR, Larson DW, Dozois E, Hayashi Y, Ordog T, Gibbons SJ, Beyder A, Farrugia G. 132 Regulation of Expression of the NaV1.5 Ion Channel by Let-7f miRNA in Human Gastrointestinal Smooth Muscle Gastroenterology. 150: S31-S32. DOI: 10.1016/S0016-5085(16)30233-5 |
0.612 |
|
| 2016 |
Choi KM, Gibbons SJ, Sha L, Beyder A, Verhulst PJ, Cipriani G, Phillips JE, Bauer AJ, Ordog T, Camp JJ, Ge X, Bharucha AE, Linden DR, Szurszewski JH, Kashyap PC, ... Farrugia G, et al. Interleukin 10 Restores Gastric Emptying, Electrical Activity, and Interstitial Cells of Cajal Networks in Diabetic Mice Cmgh Cellular and Molecular Gastroenterology and Hepatology. 2: 454-467. DOI: 10.1016/j.jcmgh.2016.04.006 |
0.556 |
|
| 2015 |
Beyder A, Gibbons SJ, Mazzone A, Strege PR, Saravanaperumal SA, Sha L, Higgins S, Eisenman ST, Bernard CE, Geurts A, Kline CF, Mohler PJ, Farrugia G. Expression and function of the Scn5a-encoded voltage-gated sodium channel NaV 1.5 in the rat jejunum. Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society. PMID 26459913 DOI: 10.1111/Nmo.12697 |
0.643 |
|
| 2015 |
Strege PR, Bernard CE, Mazzone A, Linden DR, Beyder A, Gibbons SJ, Farrugia G. A novel exon in the human Ca2+-activated Cl- channel Ano1 imparts greater sensitivity to intracellular Ca2. American Journal of Physiology. Gastrointestinal and Liver Physiology. ajpgi.00074.2015. PMID 26359375 DOI: 10.1152/Ajpgi.00074.2015 |
0.631 |
|
| 2015 |
Neshatian L, Strege PR, Rhee PL, Kraichely RE, Mazzone A, Bernard CE, Cima RR, Larson DW, Dozois EJ, Kline CF, Mohler PJ, Beyder A, Farrugia G. Ranolazine inhibits voltage-gated mechanosensitive sodium channels in human colon circular smooth muscle cells. American Journal of Physiology. Gastrointestinal and Liver Physiology. 309: G506-12. PMID 26185330 DOI: 10.1152/Ajpgi.00051.2015 |
0.641 |
|
| 2015 |
Neshatian L, Strege PR, Beyder A, Bernard CE, Mazzone A, Gibbons SJ, Tester DJ, Will ML, Mayer EA, Chang L, Ackerman MJ, Farrugia G. 677 IBS Patients Have SCN5A Mutations That Result in Decreased NaV1.5 Current and Mechanosensitivity Gastroenterology. 148: S-130-S-131. DOI: 10.1016/S0016-5085(15)30452-2 |
0.611 |
|
| 2015 |
Malysz J, Saravanaperumal SA, Eisenman ST, Cao C, Oh U, Saur D, Klein S, Ordog T, Gibbons SJ, Farrugia G. 385 Conditional Genomic Deletion of Ano1 in Kit-Expressing Cells of Adult Mice Results in Loss of Slow Waves and Reduced Coordination of Ca2+ Transients in Myenteric Interstitial Cells of Cajal of the Small Intestine Gastroenterology. 148: S-80. DOI: 10.1016/S0016-5085(15)30279-1 |
0.305 |
|
| 2014 |
Singh RD, Gibbons SJ, Saravanaperumal SA, Du P, Hennig GW, Eisenman ST, Mazzone A, Hayashi Y, Cao C, Stoltz GJ, Ordog T, Rock JR, Harfe BD, Szurszewski JH, Farrugia G. Ano1, a Ca2+-activated Cl- channel, coordinates contractility in mouse intestine by Ca2+ transient coordination between interstitial cells of Cajal. The Journal of Physiology. 592: 4051-68. PMID 25063822 DOI: 10.1113/Jphysiol.2014.277152 |
0.339 |
|
| 2014 |
Beyder A, Mazzone A, Strege PR, Tester DJ, Saito YA, Bernard CE, Enders FT, Ek WE, Schmidt PT, Dlugosz A, Lindberg G, Karling P, Ohlsson B, Gazouli M, Nardone G, ... ... Farrugia G, et al. Loss-of-function of the voltage-gated sodium channel NaV1.5 (channelopathies) in patients with irritable bowel syndrome. Gastroenterology. 146: 1659-68. PMID 24613995 DOI: 10.1053/J.Gastro.2014.02.054 |
0.634 |
|
| 2014 |
Lees-Green R, Gibbons SJ, Farrugia G, Sneyd J, Cheng LK. Computational modeling of anoctamin 1 calcium-activated chloride channels as pacemaker channels in interstitial cells of Cajal. American Journal of Physiology. Gastrointestinal and Liver Physiology. 306: G711-27. PMID 24481603 DOI: 10.1152/Ajpgi.00449.2013 |
0.375 |
|
| 2014 |
Sha L, Linden DR, Farrugia G, Szurszewski JH. Effect of endogenous hydrogen sulfide on the transwall gradient of the mouse colon circular smooth muscle. The Journal of Physiology. 592: 1077-89. PMID 24366262 DOI: 10.1113/Jphysiol.2013.266841 |
0.303 |
|
| 2014 |
Sondo E, Scudieri P, Tomati V, Caci E, Mazzone A, Farrugia G, Ravazzolo R, Galietta LJ. Non-canonical translation start sites in the TMEM16A chloride channel. Biochimica Et Biophysica Acta. 1838: 89-97. PMID 23994600 DOI: 10.1016/J.Bbamem.2013.08.010 |
0.319 |
|
| 2014 |
Neshatian L, Strege P, Larson D, Cima R, Beyder A, Farrugia G. Ranolazine Blocks NaV1.5 Peak Current and Shear Sensitivity in Human Colonic Circular Smooth Muscle: 669 The American Journal of Gastroenterology. 109. DOI: 10.14309/00000434-201410002-00669 |
0.606 |
|
| 2014 |
Neshatian L, Strege PR, Bernard CE, Beyder A, Farrugia G. Su2035 Y1767 Is Important for Block of NaV1.5 Shear Sensitivity by Ranolazine Gastroenterology. 146: S-528. DOI: 10.1016/S0016-5085(14)61913-2 |
0.568 |
|
| 2014 |
Beyder A, Strege PR, Rainey JF, Bernard CE, Giandomenico V, Kashyap PC, Farrugia G. Sa2048 Shear Sensitivity of the Voltage-Gated Sodium Selective Ion Channels (NaV) in the Neuroendocrine Cell Line QGP-1 Gastroenterology. 146: S-363. DOI: 10.1016/S0016-5085(14)61315-9 |
0.64 |
|
| 2014 |
Strege PR, Bernard CE, Mazzone A, Beyder A, Gibbons SJ, Farrugia G. 789 A Novel Exon of the Human Calcium-Activated Chloride Channel Ano1 Imparts Greater Sensitivity of Cl-Current to Intracellular CA2+ Gastroenterology. 146: S-135. DOI: 10.1016/S0016-5085(14)60477-7 |
0.628 |
|
| 2014 |
Rekdal VM, Alnahhas MF, Rainey JF, Reigstad CS, Khanna S, Grover M, Devine MDF, Chia N, Loftus EV, Boardman LA, Ahlquist DA, Pardi DS, Farrugia G, Kashyap PC. 389 Chronic Diarrhea in Subset of Patients With IBD and IBS is Associated With Altered Microbiota Gastroenterology. 146: S-83. DOI: 10.1016/S0016-5085(14)60297-3 |
0.317 |
|
| 2013 |
Hayashi Y, Toyomasu Y, Bardsley MR, Mason JE, Eisenman ST, Choi KM, Linden DR, Szurszewski JH, Rubin BP, Farrugia G, Ordog T. 163 Hyperglycemia-Induced Hyperplasia of Interstitial Cells of Cajal (ICC) and ICC Stem Cells (ICC-SC) Is Associated With Accelerated Gastric Emptying in Obese Diabetic LeprDb/Db Mice Gastroenterology. 144. DOI: 10.1016/S0016-5085(13)60134-1 |
0.31 |
|
| 2012 |
Strege P, Beyder A, Bernard C, Crespo-Diaz R, Behfar A, Terzic A, Ackerman M, Farrugia G. Ranolazine inhibits shear sensitivity of endogenous Na+ current and spontaneous action potentials in HL-1 cells. Channels (Austin, Tex.). 6: 457-62. PMID 23018927 DOI: 10.4161/Chan.22017 |
0.622 |
|
| 2012 |
Mazzone A, Eisenman ST, Strege PR, Yao Z, Ordog T, Gibbons SJ, Farrugia G. Inhibition of cell proliferation by a selective inhibitor of the Ca(2+)-activated Cl(-) channel, Ano1. Biochemical and Biophysical Research Communications. 427: 248-53. PMID 22995309 DOI: 10.1016/J.Bbrc.2012.09.022 |
0.38 |
|
| 2012 |
Beyder A, Strege PR, Bernard C, Farrugia G. Membrane permeable local anesthetics modulate Na(V)1.5 mechanosensitivity. Channels (Austin, Tex.). 6: 308-16. PMID 22874086 DOI: 10.4161/Chan.21202 |
0.617 |
|
| 2012 |
Grover M, Bernard CE, Pasricha PJ, Parkman HP, Abell TL, Nguyen LA, Snape W, Shen KR, Sarr M, Swain J, Kendrick M, Gibbons S, Ordog T, Farrugia G. Platelet-derived growth factor receptor α (PDGFRα)-expressing "fibroblast-like cells" in diabetic and idiopathic gastroparesis of humans. Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society. 24: 844-52. PMID 22650155 DOI: 10.1111/J.1365-2982.2012.01944.X |
0.369 |
|
| 2012 |
Beyder A, Strege PR, Reyes S, Bernard CE, Terzic A, Makielski J, Ackerman MJ, Farrugia G. Ranolazine decreases mechanosensitivity of the voltage-gated sodium ion channel Na(v)1.5: a novel mechanism of drug action. Circulation. 125: 2698-706. PMID 22565935 DOI: 10.1161/Circulationaha.112.094714 |
0.633 |
|
| 2012 |
Beyder A, Farrugia G. Targeting ion channels for the treatment of gastrointestinal motility disorders. Therapeutic Advances in Gastroenterology. 5: 5-21. PMID 22282704 DOI: 10.1177/1756283X11415892 |
0.651 |
|
| 2012 |
Poh YC, Beyder A, Strege PR, Farrugia G, Buist ML. Quantification of gastrointestinal sodium channelopathy. Journal of Theoretical Biology. 293: 41-8. PMID 21959314 DOI: 10.1016/J.Jtbi.2011.09.014 |
0.656 |
|
| 2012 |
Kasparek MS, Linden DR, Farrugia G, Sarr MG. Hydrogen sulfide modulates contractile function in rat jejunum. Journal of Surgical Research. 175: 234-242. PMID 21571312 DOI: 10.1016/J.Jss.2011.03.069 |
0.337 |
|
| 2012 |
Beyder A, Strege PR, Mazzone A, Bernard CE, Tester DJ, Saito YA, Ackerman MJ, Farrugia G. 1000 Missense Mutations in SCN5A From Patients With Irritable Bowel Syndrome (IBS) Result in Abnormal NaV1.5 Function Gastroenterology. 142: S-177. DOI: 10.1016/S0016-5085(12)60665-9 |
0.573 |
|
| 2012 |
Gibbons SJ, Mazzone A, Sha L, Strege PR, Higgins S, Beyder A, Farrugia G. 123 Characterization and Functional Role of the Voltage and Mechano-Sensitive Na+ Channel, Nv1.5 in Rat Small Intestine Gastroenterology. 142: S-30. DOI: 10.1016/S0016-5085(12)60118-8 |
0.634 |
|
| 2011 |
Stanich JE, Gibbons SJ, Eisenman ST, Bardsley MR, Rock JR, Harfe BD, Ordog T, Farrugia G. Ano1 as a regulator of proliferation. American Journal of Physiology. Gastrointestinal and Liver Physiology. 301: G1044-51. PMID 21940901 DOI: 10.1152/Ajpgi.00196.2011 |
0.374 |
|
| 2011 |
Lees-Green R, Du P, O'Grady G, Beyder A, Farrugia G, Pullan AJ. Biophysically based modeling of the interstitial cells of cajal: current status and future perspectives. Frontiers in Physiology. 2: 29. PMID 21772822 DOI: 10.3389/Fphys.2011.00029 |
0.587 |
|
| 2011 |
Asuzu DT, Hayashi Y, Izbeki F, Popko LN, Young DL, Bardsley MR, Lorincz A, Kuro-O M, Linden DR, Farrugia G, Ordog T. Generalized neuromuscular hypoplasia, reduced smooth muscle myosin and altered gut motility in the klotho model of premature aging. Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society. 23: e309-23. PMID 21605285 DOI: 10.1111/J.1365-2982.2011.01730.X |
0.336 |
|
| 2011 |
Strege PR, Bernard CE, Kraichely RE, Mazzone A, Sha L, Beyder A, Gibbons SJ, Linden DR, Kendrick ML, Sarr MG, Szurszewski JH, Farrugia G. Hydrogen sulfide is a partially redox-independent activator of the human jejunum Na+ channel, Nav1.5. American Journal of Physiology. Gastrointestinal and Liver Physiology. 300: G1105-14. PMID 21393430 DOI: 10.1152/Ajpgi.00556.2010 |
0.635 |
|
| 2011 |
Mazzone A, Bernard CE, Strege PR, Beyder A, Galietta LJ, Pasricha PJ, Rae JL, Parkman HP, Linden DR, Szurszewski JH, Ördög T, Gibbons SJ, Farrugia G. Altered expression of Ano1 variants in human diabetic gastroparesis. The Journal of Biological Chemistry. 286: 13393-403. PMID 21349842 DOI: 10.1074/Jbc.M110.196089 |
0.62 |
|
| 2011 |
Strege PR, Bernard CE, Beyder A, Gibbons SJ, Linden DR, Szurszewski JH, Farrugia G. Sodium Hydrogen Sulfide is a Partly Redox-Independent Activator of Na V 1.5, the Na + Channel in Human Jejunal Myocytes Gastroenterology. 140: S-375-S-376. DOI: 10.1016/S0016-5085(11)61536-9 |
0.62 |
|
| 2011 |
Lees-Green R, Beyder A, Farrugia G, O'Grady G, Poh YC, Buist M, Pullan AJ. Computational Modeling of the Human Sodium Channel: Mechanical Stretch Effects on the Electrical Function of Interstitial Cells of Cajal and Smooth Muscle Cells Gastroenterology. 140: S-120. DOI: 10.1016/S0016-5085(11)60489-7 |
0.645 |
|
| 2011 |
Beyder A, Strege PR, Mazzone A, Bernard CE, Tester DJ, Saito YA, Ackerman MJ, Farrugia G. Mutations in SCN5A From Patients With IBS Result in Abnormal Na V 1.5 Function Gastroenterology. 140: S-111. DOI: 10.1016/S0016-5085(11)60449-6 |
0.576 |
|
| 2011 |
Mazzone A, Bernard CE, Strege PR, Beyder A, Galietta LJ, Pasricha PJ, Parkman HP, Linden DR, Szurszewski JH, Ordog T, Gibbons SJ, Farrugia G. Altered Expression of Ano1 Transcript Variants in Diabetes and Gastroparesis Gastroenterology. 140: S-70. DOI: 10.1016/S0016-5085(11)60285-0 |
0.563 |
|
| 2010 |
Beyder A, Rae JL, Bernard C, Strege PR, Sachs F, Farrugia G. Mechanosensitivity of Nav1.5, a voltage-sensitive sodium channel. The Journal of Physiology. 588: 4969-85. PMID 21041530 DOI: 10.1113/Jphysiol.2010.199034 |
0.717 |
|
| 2010 |
Izbeki F, Asuzu DT, Lorincz A, Bardsley MR, Popko LN, Choi KM, Young DL, Hayashi Y, Linden DR, Kuro-o M, Farrugia G, Ordog T. Loss of Kitlow progenitors, reduced stem cell factor and high oxidative stress underlie gastric dysfunction in progeric mice. The Journal of Physiology. 588: 3101-17. PMID 20581042 DOI: 10.1113/Jphysiol.2010.191023 |
0.326 |
|
| 2010 |
Sha L, Farrugia G, Linden DR, Szurszewski JH. The transwall gradient across the mouse colonic circular muscle layer is carbon monoxide dependent. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 3840-9. PMID 20543114 DOI: 10.1096/Fj.10-156232 |
0.3 |
|
| 2010 |
Strege PR, Sha L, Beyder A, Bernard CE, Perez-Reyes E, Evangelista S, Gibbons SJ, Szurszewski JH, Farrugia G. T-type Ca(2+) channel modulation by otilonium bromide. American Journal of Physiology. Gastrointestinal and Liver Physiology. 298: G706-13. PMID 20203058 DOI: 10.1152/Ajpgi.00437.2009 |
0.607 |
|
| 2010 |
Tharayil VS, Wouters MM, Stanich JE, Roeder JL, Lei S, Beyder A, Gomez-Pinilla PJ, Gershon MD, Maroteaux L, Gibbons SJ, Farrugia G. Lack of serotonin 5-HT2B receptor alters proliferation and network volume of interstitial cells of Cajal in vivo. Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society. 22: 462-9, e109-10. PMID 19941613 DOI: 10.1111/J.1365-2982.2009.01435.X |
0.586 |
|
| 2010 |
Beyder A, Rae JL, Strege PR, Bernard CE, Sachs F, Farrugia G. T2067 Mechanosensitivity of NaV1.5, a Voltage-Gated Sodium Selective Ion Channel Found in the Human Gastrointestinal Tract Gastroenterology. 138: S-625. DOI: 10.1016/S0016-5085(10)62880-6 |
0.656 |
|
| 2010 |
Beyder A, Rae JL, Bernard C, Farrugia G. Mechanosensitivity of a Voltage-Gated Ion Channel, Nav1.5 Biophysical Journal. 98: 323a. DOI: 10.1016/J.Bpj.2009.12.1754 |
0.654 |
|
| 2009 |
Huizinga JD, Zarate N, Farrugia G. Physiology, injury, and recovery of interstitial cells of Cajal: basic and clinical science. Gastroenterology. 137: 1548-56. PMID 19778538 DOI: 10.1053/J.Gastro.2009.09.023 |
0.313 |
|
| 2009 |
Gibbons SJ, Strege PR, Lei S, Roeder JL, Mazzone A, Ou Y, Rich A, Farrugia G. The α1H Ca2+ channel subunit is expressed in mouse jejunal interstitial cells of Cajal and myocytes Journal of Cellular and Molecular Medicine. 13: 4422-4431. PMID 19413888 DOI: 10.1111/J.1582-4934.2008.00623.X |
0.379 |
|
| 2009 |
Gomez-Pinilla PJ, Gibbons SJ, Bardsley MR, Lorincz A, Pozo MJ, Pasricha PJ, Van de Rijn M, West RB, Sarr MG, Kendrick ML, Cima RR, Dozois EJ, Larson DW, Ordog T, Farrugia G. Ano1 is a selective marker of interstitial cells of Cajal in the human and mouse gastrointestinal tract. American Journal of Physiology. Gastrointestinal and Liver Physiology. 296: G1370-81. PMID 19372102 DOI: 10.1152/Ajpgi.00074.2009 |
0.342 |
|
| 2009 |
Kraichely RE, Strege PR, Sarr MG, Kendrick ML, Farrugia G. Lysophosphatidyl choline modulates mechanosensitive L-type Ca2+ current in circular smooth muscle cells from human jejunum American Journal of Physiology-Gastrointestinal and Liver Physiology. 296. PMID 19179622 DOI: 10.1152/Ajpgi.90610.2008 |
0.325 |
|
| 2009 |
Saito YA, Strege PR, Tester DJ, Locke GR, Talley NJ, Bernard CE, Rae JL, Makielski JC, Ackerman MJ, Farrugia G. Sodium channel mutation in irritable bowel syndrome: evidence for an ion channelopathy. American Journal of Physiology. Gastrointestinal and Liver Physiology. 296: G211-8. PMID 19056759 DOI: 10.1152/Ajpgi.90571.2008 |
0.388 |
|
| 2009 |
Gibbons SJ, Giorgio RD, Pellegrini MSF, Garrity‐park MM, Miller SM, Schmalz PF, Young‐fadok TM, Larson DW, Dozois EJ, Camilleri M, Stanghellini V, Szurszewski JH, Farrugia G. Apoptotic cell death of human interstitial cells of Cajal. Neurogastroenterology and Motility. 21: 85-93. PMID 18798796 DOI: 10.1111/J.1365-2982.2008.01185.X |
0.305 |
|
| 2008 |
Ueda K, Valdivia C, Medeiros-Domingo A, Tester DJ, Vatta M, Farrugia G, Ackerman MJ, Makielski JC. Syntrophin mutation associated with long QT syndrome through activation of the nNOS-SCN5A macromolecular complex. Proceedings of the National Academy of Sciences of the United States of America. 105: 9355-60. PMID 18591664 DOI: 10.1073/Pnas.0801294105 |
0.339 |
|
| 2008 |
Pasricha PJ, Pehlivanov ND, Gomez G, Vittal H, Lurken MS, Farrugia G. Changes in the gastric enteric nervous system and muscle: a case report on two patients with diabetic gastroparesis. Bmc Gastroenterology. 8: 21. PMID 18513423 DOI: 10.1186/1471-230X-8-21 |
0.306 |
|
| 2008 |
Mazzone A, Strege PR, Tester DJ, Bernard CE, Faulkner G, De Giorgio R, Makielski JC, Stanghellini V, Gibbons SJ, Ackerman MJ, Farrugia G. A mutation in telethonin alters Nav1.5 function. The Journal of Biological Chemistry. 283: 16537-44. PMID 18408010 DOI: 10.1074/Jbc.M801744200 |
0.398 |
|
| 2008 |
Farrugia G. Interstitial cells of Cajal in health and disease. Neurogastroenterology and Motility. 20: 54-63. PMID 18402642 DOI: 10.1111/J.1365-2982.2008.01109.X |
0.32 |
|
| 2007 |
Vittal H, Farrugia G, Gomez G, Pasricha PJ. Mechanisms of disease: the pathological basis of gastroparesis--a review of experimental and clinical studies. Nature Clinical Practice. Gastroenterology & Hepatology. 4: 336-46. PMID 17541447 DOI: 10.1038/Ncpgasthep0838 |
0.307 |
|
| 2007 |
Kraichely RE, Farrugia G. Mechanosensitive ion channels in interstitial cells of Cajal and smooth muscle of the gastrointestinal tract Neurogastroenterology and Motility. 19: 245-252. PMID 17391240 DOI: 10.1111/J.1365-2982.2006.00880.X |
0.386 |
|
| 2007 |
Strege PR, Mazzone A, Kraichely RE, Sha L, Holm AN, Ou Y, Lim I, Gibbons SJ, Sarr MG, Farrugia G. Species dependent expression of intestinal smooth muscle mechanosensitive sodium channels. Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society. 19: 135-43. PMID 17244168 DOI: 10.1111/J.1365-2982.2006.00844.X |
0.383 |
|
| 2006 |
Locke GR, Ackerman MJ, Zinsmeister AR, Thapa P, Farrugia G. Gastrointestinal symptoms in families of patients with an SCN5A-encoded cardiac channelopathy: Evidence of an intestinal channelopathy American Journal of Gastroenterology. 101: 1299-1304. PMID 16771953 DOI: 10.1111/J.1572-0241.2006.00507.X |
0.322 |
|
| 2005 |
Strege PR, Bernard CE, Ou Y, Gibbons SJ, Farrugia G. Effect of mibefradil on sodium and calcium currents American Journal of Physiology - Gastrointestinal and Liver Physiology. 289. PMID 15790762 DOI: 10.1152/Ajpgi.00022.2005 |
0.356 |
|
| 2005 |
Lim I, Gibbons SJ, Lyford GL, Miller SM, Strege PR, Sarr MG, Chatterjee S, Szurszewski JH, Shah VH, Farrugia G. Carbon monoxide activates human intestinal smooth muscle L-type Ca2+ channels through a nitric oxide-dependent mechanism. American Journal of Physiology-Gastrointestinal and Liver Physiology. 288. PMID 15319183 DOI: 10.1152/Ajpgi.00205.2004 |
0.332 |
|
| 2004 |
Strege PR, Evangelista S, Lyford GL, Sarr MG, Farrugia G. Otilonium bromide inhibits calcium entry through L-type calcium channels in human intestinal smooth muscle. Neurogastroenterology and Motility. 16: 167-173. PMID 15086870 DOI: 10.1111/J.1365-2982.2004.00517.X |
0.344 |
|
| 2004 |
Szurszewski JH, Farrugia G. Carbon monoxide is an endogenous hyperpolarizing factor in the gastrointestinal tract. Neurogastroenterology and Motility. 16: 81-85. PMID 15066010 DOI: 10.1111/J.1743-3150.2004.00480.X |
0.332 |
|
| 2003 |
Lyford GL, Farrugia G. Ion channels in gastrointestinal smooth muscle and interstitial cells of Cajal. Current Opinion in Pharmacology. 3: 583-587. PMID 14644008 DOI: 10.1016/J.Coph.2003.06.010 |
0.388 |
|
| 2003 |
Strege PR, Ou Y, Sha L, Rich A, Gibbons SJ, Szurszewski JH, Sarr MG, Farrugia G. Sodium current in human intestinal interstitial cells of Cajal. American Journal of Physiology. Gastrointestinal and Liver Physiology. 285: G1111-21. PMID 12893628 DOI: 10.1152/Ajpgi.00152.2003 |
0.341 |
|
| 2003 |
Farrugia G, Lei S, Lin X, Miller SM, Nath KA, Ferris CD, Levitt M, Szurszewski JH. A major role for carbon monoxide as an endogenous hyperpolarizing factor in the gastrointestinal tract. Proceedings of the National Academy of Sciences of the United States of America. 100: 8567-70. PMID 12832617 DOI: 10.1073/Pnas.1431233100 |
0.326 |
|
| 2003 |
Strege PR, Holm AN, Rich A, Miller SM, Ou Y, Sarr MG, Farrugia G. Cytoskeletal modulation of sodium current in human jejunal circular smooth muscle cells American Journal of Physiology-Cell Physiology. 284. PMID 12475760 DOI: 10.1152/Ajpcell.00532.2001 |
0.35 |
|
| 2002 |
Ou Y, Gibbons SJ, Miller SM, Strege PR, Rich A, Distad MA, Ackerman MJ, Rae JL, Szurszewski JH, Farrugia G. SCN5A is expressed in human jejunal circular smooth muscle cells. Neurogastroenterology and Motility. 14: 477-486. PMID 12358675 DOI: 10.1046/J.1365-2982.2002.00348.X |
0.36 |
|
| 2002 |
Lyford GL, He CL, Soffer E, Hull TL, Strong SA, Senagore AJ, Burgart LJ, Young-Fadok T, Szurszewski JH, Farrugia G. Pan-colonic decrease in interstitial cells of Cajal in patients with slow transit constipation Gut. 51: 496-501. PMID 12235070 DOI: 10.1136/Gut.51.4.496 |
0.307 |
|
| 2002 |
Lyford GL, Strege PR, Shepard A, Ou Y, Ermilov L, Miller SM, Gibbons SJ, Rae JL, Szurszewski JH, Farrugia G. alpha(1C) (Ca(V)1.2) L-type calcium channel mediates mechanosensitive calcium regulation. American Journal of Physiology. Cell Physiology. 283: C1001-8. PMID 12176756 DOI: 10.1152/Ajpcell.00140.2002 |
0.313 |
|
| 2002 |
Holm AN, Rich A, Miller SM, Strege P, Ou Y, Gibbons S, Sarr MG, Szurszewski JH, Rae JL, Farrugia G. Sodium current in human jejunal circular smooth muscle cells. Gastroenterology. 122: 178-87. PMID 11781292 DOI: 10.1053/Gast.2002.30346 |
0.402 |
|
| 2002 |
Pardi DS, Miller SM, Miller DL, Burgart LJ, Szurszewski JH, Lennon VA, Farrugia G. Paraneoplastic dysmotility: loss of interstitial cells of Cajal. The American Journal of Gastroenterology. 97: 1828-1833. DOI: 10.1016/S0002-9270(02)04207-7 |
0.318 |
|
| 2002 |
Malysz J, Farrugia G, Ou Y, Szurszewski JH, Nehra A, Gibbons SJ. The Kv2.2 α Subunit Contributes to Delayed Rectifier K+ Currents in Myocytes From Rabbit Corpus Cavernosum Journal of Andrology. 23: 899-910. DOI: 10.1002/J.1939-4640.2002.Tb02348.X |
0.331 |
|
| 2001 |
Malysz J, Gibbons SJ, Miller SM, Gettman M, Nehra A, Szurszewski JH, Farrugia G. Potassium Outward Currents In Freshly Dissociated Rabbit Corpus Cavernosum Myocytes The Journal of Urology. 166: 1167-1177. DOI: 10.1016/S0022-5347(05)65940-X |
0.368 |
|
| 2001 |
Strege PR, Rich AJ, Ou Y, Gibbons SJ, Sarr MG, Szurszewski JH, Farrugia G. Sodium current in human small intestinal interstitial cells of cajal Gastroenterology. 120. DOI: 10.1016/S0016-5085(08)80994-8 |
0.342 |
|
| 2000 |
Holm AN, Rich A, Sarr MG, Farrugia G. Whole cell current and membrane potential regulation by a human smooth muscle mechanosensitive calcium channel. American Journal of Physiology-Gastrointestinal and Liver Physiology. 279. PMID 11093937 DOI: 10.1152/Ajpgi.2000.279.6.G1155 |
0.389 |
|
| 2000 |
He C, Burgart L, Wang L, Pemberton J, Young–Fadok T, Szurszewski J, Farrugia G. Decreased interstitial cell of Cajal volume in patients with slow-transit constipation Gastroenterology. 118: 14-21. PMID 10611149 DOI: 10.1016/S0016-5085(00)70409-4 |
0.318 |
|
| 2000 |
Holm AN, Rich A, Sarr MG, Szurszewski JH, Farrugia G. The mechano-sensitive calcium current in human jejunal circular smooth muscle cells is made up of two components Gastroenterology. 118. DOI: 10.1016/S0016-5085(00)85575-4 |
0.311 |
|
| 1999 |
Farrugia G, Szurszewski JH. Heme oxygenase, carbon monoxide, and interstitial cells of Cajal. Microscopy Research and Technique. 47: 321-324. PMID 10602291 DOI: 10.1002/(Sici)1097-0029(19991201)47:5<321::Aid-Jemt3>3.0.Co;2-J |
0.331 |
|
| 1999 |
Farrugia G, Holm AN, Rich A, Sarr MG, Szurszewski JH, Rae JL. A mechanosensitive calcium channel in human intestinal smooth muscle cells. Gastroenterology. 117: 900-905. PMID 10500073 DOI: 10.1016/S0016-5085(99)70349-5 |
0.379 |
|
| 1999 |
Farrugia G. Ionic Conductances In Gastrointestinal Smooth Muscles And Interstitial Cells Of Cajal Annual Review of Physiology. 61: 45-84. PMID 10099682 DOI: 10.1146/Annurev.Physiol.61.1.45 |
0.386 |
|
| 1998 |
Farrugia G, Miller SM, Rich A, Liu X, Maines MD, Rae JL, Szurszewski JH. Distribution of heme oxygenase and effects of exogenous carbon monoxide in canine jejunum. American Journal of Physiology. Gastrointestinal and Liver Physiology. 274: G350-G358. PMID 29591594 DOI: 10.1152/Ajpgi.1998.274.2.G350 |
0.335 |
|
| 1997 |
Farrugia G. G-protein regulation of an L-type calcium channel current in canine jejunal circular smooth muscle. The Journal of Membrane Biology. 160: 39-46. PMID 9351890 DOI: 10.1007/S002329900293 |
0.339 |
|
| 1997 |
Farrugia G, Macielag MJ, Peeters TL, Sarr MG, Galdes A, Szurszewski JH. Motilin and OHM-11526 activate a calcium current in human and canine jejunal circular smooth muscle. American Journal of Physiology-Gastrointestinal and Liver Physiology. 273. PMID 9277420 DOI: 10.1152/Ajpgi.1997.273.2.G404 |
0.339 |
|
| 1997 |
Rich A, Bartling C, Farrugia G, Rae JL. Effects of pH on the potassium current in rabbit corneal epithelial cells American Journal of Physiology-Cell Physiology. 272. PMID 9124319 DOI: 10.1152/Ajpcell.1997.272.2.C744 |
0.306 |
|
| 1996 |
Farrugia G. Modulation of ionic currents in isolated canine and human jejunal circular smooth muscle cells by fluoxetine Gastroenterology. 110: 1438-1445. PMID 8613049 DOI: 10.1053/Gast.1996.V110.Pm8613049 |
0.333 |
|
| 1995 |
Farrugia G, Rich A, Rae JL, Sarr MG, Szurszewski JH. Calcium currents in human and canine jejunal circular smooth muscle cells. Gastroenterology. 109: 707-717. PMID 7544750 DOI: 10.1016/0016-5085(95)90377-1 |
0.33 |
|
| 1994 |
Rich A, Farrugia G, Rae JL. Carbon monoxide stimulates a potassium-selective current in rabbit corneal epithelial cells. American Journal of Physiology-Cell Physiology. 267. PMID 8074178 DOI: 10.1152/Ajpcell.1994.267.2.C435 |
0.368 |
|
| 1994 |
Farrugia G, Rich A, Rae JL, Szurszewski JH. Activation of a whole cell current in canine jejunal circular smooth muscle cells by carbon monoxide — A model for the human jejunum Gastroenterology. 107: 1226. DOI: 10.1016/0016-5085(94)90301-8 |
0.316 |
|
| 1994 |
Farrugia G, Rich A, Lu G, Sarr MG, Rae JL, Szurszewski JH. Effect of erythromycin on dihydropyridine sensitive calcium channels and intracellular calcium in human and canine jejunal circular smooth muscle cells Gastroenterology. 107: 1226. DOI: 10.1016/0016-5085(94)90300-X |
0.332 |
|
| 1993 |
Farrugia G, Rae J. Effect of volume changes on a potassium current in rabbit corneal epithelial cells. American Journal of Physiology-Cell Physiology. 264. PMID 8498483 DOI: 10.1152/Ajpcell.1993.264.5.C1238 |
0.359 |
|
| 1993 |
Farrugia G, Irons WA, Rae JL, Sarr MG, Szurszewski JH. Activation of whole cell currents in isolated human jejunal circular smooth muscle cells by carbon monoxide American Journal of Physiology-Gastrointestinal and Liver Physiology. 264. PMID 8392811 DOI: 10.1152/Ajpgi.1993.264.6.G1184 |
0.352 |
|
| 1993 |
Farrugia G, Rae JL, Szurszewski JH. Characterization of an outward potassium current in canine jejunal circular smooth muscle and its activation by fenamates. The Journal of Physiology. 468: 297-310. PMID 8254511 DOI: 10.1113/Jphysiol.1993.Sp019772 |
0.335 |
|
| 1993 |
Farrugia G, Rae JL, Sarr MG, Szurszewski JH. Potassium current in circular smooth muscle of human jejunum activated by fenamates American Journal of Physiology-Gastrointestinal and Liver Physiology. 265. PMID 8238516 DOI: 10.1152/Ajpgi.1993.265.5.G873 |
0.337 |
|
| 1992 |
Rae JL, Farrugia G. Whole-cell potassium current in rabbit corneal epithelium activated by fenamates. The Journal of Membrane Biology. 129: 81-97. PMID 1404342 DOI: 10.1007/Bf00232057 |
0.382 |
|
| 1992 |
Farrugia G, Raet JL. Regulation of a potassium-selective current in rabbit corneal epithelium by cyclic GMP, carbachol and diltiazem. The Journal of Membrane Biology. 129: 99-107. PMID 1328648 DOI: 10.1007/Bf00232058 |
0.371 |
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