Year |
Citation |
Score |
2023 |
Werman JM, Chen YC, Yuan T, Yang X, Sampson NS. A Chemoproteomic Approach to Elucidate the Mechanism of Action of 6-Azasteroids with Unique Activity in Mycobacteria. Acs Infectious Diseases. 9: 1993-2004. PMID 37774412 DOI: 10.1021/acsinfecdis.3c00296 |
0.641 |
|
2021 |
Rosa TLSA, Marques MAM, DeBoard Z, Hutchins K, Silva CAA, Montague CR, Yuan T, Amaral JJ, Atella GC, Rosa PS, Mattos KA, VanderVen BC, Lahiri R, Sampson NS, Brennan PJ, et al. Corrigendum: Reductive Power Generated by Through Cholesterol Oxidation Contributes to Lipid and ATP Synthesis. Frontiers in Cellular and Infection Microbiology. 11: 765326. PMID 34650934 DOI: 10.3389/fcimb.2021.765326 |
0.548 |
|
2021 |
Rosa TLSA, Marques MAM, DeBoard Z, Hutchins K, Silva CAA, Montague CR, Yuan T, Amaral JJ, Atella GC, Rosa PS, Mattos KA, VanderVen BC, Lahiri R, Sampson NS, Brennan PJ, et al. Reductive Power Generated by Through Cholesterol Oxidation Contributes to Lipid and ATP Synthesis. Frontiers in Cellular and Infection Microbiology. 11: 709972. PMID 34395315 DOI: 10.3389/fcimb.2021.709972 |
0.625 |
|
2021 |
Yuan T, Werman JM, Sampson NS. The pursuit of mechanism of action: uncovering drug complexity in TB drug discovery. Rsc Chemical Biology. 2: 423-440. PMID 33928253 DOI: 10.1039/d0cb00226g |
0.577 |
|
2021 |
Yuan T, Werman JM, Yin X, Yang M, Garcia-Diaz M, Sampson NS. Enzymatic β-Oxidation of the Cholesterol Side Chain in Bifurcates Stereospecifically at Hydration of 3-Oxo-cholest-4,22-dien-24-oyl-CoA. Acs Infectious Diseases. PMID 33826843 DOI: 10.1021/acsinfecdis.1c00069 |
0.654 |
|
2020 |
Bonds A, Yuan T, Werman J, Jang J, Lu R, Nesbitt NM, Garcia-Diaz M, Sampson NS. Post-translational succinylation of enoyl-CoA hydratase EchA19 slows catalytic hydration of cholesterol catabolite 3-oxo-chol-4,22-diene-24-oyl-CoA. Acs Infectious Diseases. PMID 32649175 DOI: 10.1021/Acsinfecdis.0C00329 |
0.654 |
|
2020 |
Gadbery J, Round J, Yuan T, Wipperman MF, Story KT, Crowe A, Casabon I, Liu J, Yang X, Eltis LD, Sampson NS. IpdE1-IpdE2 is a heterotetrameric acyl coenzyme A dehydrogenase that is widely distributed in steroid-degrading bacteria. Biochemistry. PMID 32101684 DOI: 10.1021/Acs.Biochem.0C00005 |
0.644 |
|
2019 |
Yuan T, Yang M, Gehring K, Sampson NS. exploits a heterohexameric enoyl-CoA hydratase retro-aldolase complex for cholesterol catabolism. Biochemistry. PMID 31568719 DOI: 10.1021/Acs.Biochem.9B00673 |
0.648 |
|
2019 |
Yuan T, Sampson NS. Correction to Hit Generation in TB Drug Discovery: From Genome to Granuloma. Chemical Reviews. PMID 31058490 DOI: 10.1021/Acs.Chemrev.9B00244 |
0.583 |
|
2019 |
Yang X, Yuan T, Ma R, Chacko K, Smith M, Deikus G, Sebra R, Kasarkskis A, van Bakel H, Franzblau SG, Sampson NS. The Mce3R stress-resistance pathway is vulnerable to small molecule targeting that improves tuberculosis drug activities. Acs Infectious Diseases. PMID 31012313 DOI: 10.1021/Acsinfecdis.9B00099 |
0.672 |
|
2018 |
Yuan T, Sampson NS. Hit Generation in TB Drug Discovery: From Genome to Granuloma. Chemical Reviews. PMID 29384369 DOI: 10.1021/Acs.Chemrev.7B00602 |
0.609 |
|
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