| Year |
Citation |
Score |
| 2018 |
Moustakim M, Riedel K, Schuller M, Gehring AP, Monteiro OP, Martin SP, Fedorov O, Heer J, Dixon DJ, Elkins JM, Knapp S, Bracher F, Brennan PE. Discovery of a novel allosteric inhibitor scaffold for polyadenosine-diphosphate-ribose polymerase 14 (PARP14) macrodomain 2. Bioorganic & Medicinal Chemistry. PMID 29567296 DOI: 10.1016/J.Bmc.2018.03.020 |
0.374 |
|
| 2007 |
Howard-Jones AR, Elkins JM, Clifton IJ, Roach PL, Adlington RM, Baldwin JE, Rutledge PJ. Interactions of isopenicillin N synthase with cyclopropyl-containing substrate analogues reveal new mechanistic insight Biochemistry. 46: 4755-4762. PMID 17397141 DOI: 10.1021/Bi062314Q |
0.726 |
|
| 2005 |
Elkins JM, Kershaw NJ, Schofield CJ. X-ray crystal structure of ornithine acetyltransferase from the clavulanic acid biosynthesis gene cluster. The Biochemical Journal. 385: 565-73. PMID 15352873 DOI: 10.1042/Bj20040814 |
0.544 |
|
| 2003 |
Caines ME, Elkins JM, Hewitson KS, Schofield CJ. Crystal structure and mechanistic implications of N2-(2-carboxyethyl)arginine synthase, the first enzyme in the clavulanic acid biosynthesis pathway. The Journal of Biological Chemistry. 279: 5685-92. PMID 14623876 DOI: 10.1074/Jbc.M310803200 |
0.578 |
|
| 2003 |
Elkins JM, Rutledge PJ, Burzlaff NI, Clifton IJ, Adlington RM, Roach PL, Baldwin JE. Crystallographic studies on the reaction of isopenicillin N synthase with an unsaturated substrate analogue. Organic & Biomolecular Chemistry. 1: 1455-60. PMID 12926272 DOI: 10.1039/B212270G |
0.726 |
|
| 2003 |
Hewitson KS, McNeill LA, Elkins JM, Schofield CJ. The role of iron and 2-oxoglutarate oxygenases in signalling. Biochemical Society Transactions. 31: 510-5. PMID 12773146 DOI: 10.1042/Bst0310510 |
0.4 |
|
| 2003 |
Elkins JM, Hewitson KS, McNeill LA, Seibel JF, Schlemminger I, Pugh CW, Ratcliffe PJ, Schofield CJ. Structure of factor-inhibiting hypoxia-inducible factor (HIF) reveals mechanism of oxidative modification of HIF-1 alpha. The Journal of Biological Chemistry. 278: 1802-6. PMID 12446723 DOI: 10.1074/Jbc.C200644200 |
0.5 |
|
| 2003 |
Elkins JM, Rutledge PJ, Burzlaff NI, Clifton IJ, Adlington RM, Roach PL, Baldwin JE. Crystallographic studies on the reaction of isopenicillin N synthase with an unsaturated substrate analogue Organic and Biomolecular Chemistry. 1: 1455-1460. DOI: 10.1039/b212270g |
0.696 |
|
| 2002 |
Rutledge PJ, Burzlaff NI, Elkins JM, Pickford M, Baldwin JE, Roach PL. A device for the high-pressure oxygenation of protein crystals. Analytical Biochemistry. 308: 265-8. PMID 12419338 DOI: 10.1016/S0003-2697(02)00246-4 |
0.681 |
|
| 2002 |
Hewitson KS, McNeill LA, Riordan MV, Tian YM, Bullock AN, Welford RW, Elkins JM, Oldham NJ, Bhattacharya S, Gleadle JM, Ratcliffe PJ, Pugh CW, Schofield CJ. Hypoxia-inducible factor (HIF) asparagine hydroxylase is identical to factor inhibiting HIF (FIH) and is related to the cupin structural family. The Journal of Biological Chemistry. 277: 26351-5. PMID 12042299 DOI: 10.1074/Jbc.C200273200 |
0.458 |
|
| 2002 |
Elkins JM, Clifton IJ, Hernández H, Doan LX, Robinson CV, Schofield CJ, Hewitson KS. Oligomeric structure of proclavaminic acid amidino hydrolase: evolution of a hydrolytic enzyme in clavulanic acid biosynthesis. The Biochemical Journal. 366: 423-34. PMID 12020346 DOI: 10.1042/Bj20020125 |
0.518 |
|
| 2002 |
Elkins JM, Ryle MJ, Clifton IJ, Dunning Hotopp JC, Lloyd JS, Burzlaff NI, Baldwin JE, Hausinger RP, Roach PL. X-ray crystal structure of Escherichia coli taurine/alpha-ketoglutarate dioxygenase complexed to ferrous iron and substrates. Biochemistry. 41: 5185-92. PMID 11955067 DOI: 10.1021/Bi016014E |
0.685 |
|
| 2001 |
Ogle JM, Clifton IJ, Rutledge PJ, Elkins JM, Burzlaff NI, Adlington RM, Roach PL, Baldwin JE. Alternative oxidation by isopenicillin N synthase observed by X-ray diffraction. Chemistry & Biology. 8: 1231-7. PMID 11755401 DOI: 10.1016/S1074-5521(01)00090-4 |
0.728 |
|
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