| Year |
Citation |
Score |
| 2024 |
Lazzarino M, Zanetti M, Chen SN, Gao S, Peña B, Lam CK, Wu JC, Taylor MRG, Mestroni L, Sbaizero O. Defective Biomechanics and Pharmacological Rescue of Human Cardiomyocytes with Filamin C Truncations. International Journal of Molecular Sciences. 25. PMID 38474188 DOI: 10.3390/ijms25052942 |
0.484 |
|
| 2024 |
Gao S, He L, Lam CK, Taylor MRG, Mestroni L, Lombardi R, Chen SN. Filamin C Deficiency Impairs Sarcomere Stability and Activates Focal Adhesion Kinase through PDGFRA Signaling in Induced Pluripotent Stem Cell-Derived Cardiomyocytes. Cells. 13. PMID 38334670 DOI: 10.3390/cells13030278 |
0.429 |
|
| 2023 |
Tu C, Caudal A, Liu Y, Gorgodze N, Zhang H, Lam CK, Dai Y, Zhang A, Wnorowski A, Wu MA, Yang H, Abilez OJ, Lyu X, Narayan SM, Mestroni L, et al. Tachycardia-induced metabolic rewiring as a driver of contractile dysfunction. Nature Biomedical Engineering. PMID 38012305 DOI: 10.1038/s41551-023-01134-x |
0.745 |
|
| 2023 |
Ramachandran A, Livingston CE, Vite A, Corbin EA, Bennett AI, Turner KT, Lee BW, Lam CK, Wu JC, Margulies KB. Biomechanical Impact of Pathogenic MYBPC3 Truncation Variant Revealed by Dynamically Tuning In Vitro Afterload. Journal of Cardiovascular Translational Research. PMID 36877449 DOI: 10.1007/s12265-022-10348-4 |
0.468 |
|
| 2022 |
Wang YJ, Zhang X, Lam CK, Guo H, Wang C, Zhang S, Wu JC, Snyder M, Li J. Systems analysis of de novo mutations in congenital heart diseases identified a protein network in the hypoplastic left heart syndrome. Cell Systems. PMID 36167075 DOI: 10.1016/j.cels.2022.09.001 |
0.441 |
|
| 2022 |
Chen SN, Lam CK, Wan YW, Gao S, Malak OA, Zhao SR, Lombardi R, Ambardekar AV, Bristow MR, Cleveland J, Gigli M, Sinagra G, Graw S, Taylor MRG, Wu JC, et al. Activation of PDGFRA signaling contributes to filamin C-related arrhythmogenic cardiomyopathy. Science Advances. 8: eabk0052. PMID 35196083 DOI: 10.1126/sciadv.abk0052 |
0.605 |
|
| 2021 |
Roberts RJ, Hallee L, Lam CK. The Potential of Hsp90 in Targeting Pathological Pathways in Cardiac Diseases. Journal of Personalized Medicine. 11. PMID 34945845 DOI: 10.3390/jpm11121373 |
0.408 |
|
| 2021 |
Sen S, Hallee L, Lam CK. The Potential of Gamma Secretase as a Therapeutic Target for Cardiac Diseases. Journal of Personalized Medicine. 11. PMID 34945766 DOI: 10.3390/jpm11121294 |
0.643 |
|
| 2021 |
Lam CK, Wu JC. Clinical Trial in a Dish: Using Patient-Derived Induced Pluripotent Stem Cells to Identify Risks of Drug-Induced Cardiotoxicity. Arteriosclerosis, Thrombosis, and Vascular Biology. ATVBAHA120314695. PMID 33472401 DOI: 10.1161/ATVBAHA.120.314695 |
0.494 |
|
| 2020 |
Feyen DAM, McKeithan WL, Bruyneel AAN, Spiering S, Hörmann L, Ulmer B, Zhang H, Briganti F, Schweizer M, Hegyi B, Liao Z, Pölönen RP, Ginsburg KS, Lam CK, Serrano R, et al. Metabolic Maturation Media Improve Physiological Function of Human iPSC-Derived Cardiomyocytes. Cell Reports. 32: 107925. PMID 32697997 DOI: 10.1016/J.Celrep.2020.107925 |
0.574 |
|
| 2020 |
Rhee JW, Yi H, Thomas D, Lam CK, Belbachir N, Tian L, Qin X, Malisa J, Lau E, Paik DT, Kim Y, Choi BS, Sayed N, Sallam K, Liao R, et al. Modeling Secondary Iron Overload Cardiomyopathy with Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes. Cell Reports. 32: 107886. PMID 32668256 DOI: 10.1016/J.Celrep.2020.107886 |
0.762 |
|
| 2019 |
Lee J, Termglinchan V, Diecke S, Itzhaki I, Lam CK, Garg P, Lau E, Greenhaw M, Seeger T, Wu H, Zhang JZ, Chen X, Gil IP, Ameen M, Sallam K, et al. Activation of PDGF pathway links LMNA mutation to dilated cardiomyopathy. Nature. PMID 31316208 DOI: 10.1038/S41586-019-1406-X |
0.725 |
|
| 2019 |
Wu H, Yang H, Rhee JW, Zhang JZ, Lam CK, Sallam K, Chang ACY, Ma N, Lee J, Zhang H, Blau HM, Bers DM, Wu JC. Modelling diastolic dysfunction in induced pluripotent stem cell-derived cardiomyocytes from hypertrophic cardiomyopathy patients. European Heart Journal. PMID 31219556 DOI: 10.1093/Eurheartj/Ehz326 |
0.781 |
|
| 2019 |
Lam CK, Tian L, Belbachir N, Shrestha R, Ma N, Kitani T, Rhee JW, Wnorowski A, Wu JC. Identifying the Transcriptome Signatures of Calcium Channel Blockers in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes. Circulation Research. PMID 31079550 DOI: 10.1161/Circresaha.118.314202 |
0.749 |
|
| 2019 |
Zhang JZ, Termglinchan V, Shao NY, Itzhaki I, Liu C, Ma N, Tian L, Wang VY, Chang ACY, Guo H, Kitani T, Wu H, Lam CK, Kodo K, Sayed N, et al. A Human iPSC Double-Reporter System Enables Purification of Cardiac Lineage Subpopulations with Distinct Function and Drug Response Profiles. Cell Stem Cell. PMID 30880024 DOI: 10.1016/J.Stem.2019.02.015 |
0.751 |
|
| 2019 |
Kitani T, Ong SG, Lam CK, Rhee JW, Zhang JZ, Oikonomopoulos A, Ma N, Tian L, Lee J, Telli ML, Witteles RM, Sharma A, Sayed N, Wu JC. Human Induced Pluripotent Stem Cell Model of Trastuzumab-Induced Cardiac Dysfunction in Breast Cancer Patients. Circulation. PMID 30866650 DOI: 10.1161/Circulationaha.118.037357 |
0.764 |
|
| 2018 |
Seeger T, Shrestha R, Lam CK, Chen C, McKeithan WL, Lau E, Wnorowski A, McMullen G, Greenhaw M, Lee J, Oikonomopoulos A, Lee S, Yang H, Mercola M, Wheeler M, et al. A Premature Termination Codon Mutation in MYBPC3 Causes Hypertrophic Cardiomyopathy via Chronic Activation of Nonsense-Mediated Decay. Circulation. PMID 30586709 DOI: 10.1161/Circulationaha.118.034624 |
0.742 |
|
| 2018 |
Lam CK, Wu JC. Disease modelling and drug discovery for hypertrophic cardiomyopathy using pluripotent stem cells: how far have we come? European Heart Journal. PMID 30010924 DOI: 10.1093/Eurheartj/Ehy388 |
0.487 |
|
| 2018 |
Garg P, Oikonomopoulos A, Chen H, Li Y, Lam CK, Sallam K, Perez M, Lux RL, Sanguinetti MC, Wu JC. Genome Editing of Induced Pluripotent Stem Cells to Decipher Cardiac Channelopathy Variant. Journal of the American College of Cardiology. 72: 62-75. PMID 29957233 DOI: 10.1016/J.Jacc.2018.04.041 |
0.765 |
|
| 2018 |
Ma N, Zhang J, Itzhaki I, Zhang SL, Chen H, Haddad F, Kitani T, Wilson KD, Tian L, Shrestha R, Wu H, Lam CK, Sayed N, Wu JC. Determining the Pathogenicity of a Genomic Variant of Uncertain Significance Using CRISPR/Cas9 and Human-Induced Pluripotent Stem Cells. Circulation. PMID 29914921 DOI: 10.1161/Circulationaha.117.032273 |
0.78 |
|
| 2018 |
Liu GS, Gardner G, Adly G, Jiang M, Cai WF, Lam CK, Alogaili F, Robbins N, Rubinstein J, Kranias EG. A novel human S10F-Hsp20 mutation induces lethal peripartum cardiomyopathy. Journal of Cellular and Molecular Medicine. PMID 29761889 DOI: 10.1111/Jcmm.13665 |
0.335 |
|
| 2016 |
Liang P, Sallam K, Wu H, Li Y, Itzhaki I, Garg P, Zhang Y, Vermglinchan V, Lan F, Gu M, Gong T, Zhuge Y, He C, Ebert AD, Sanchez-Freire V, ... ... Lam CK, et al. Patient-Specific and Genome-Edited Induced Pluripotent Stem Cell-Derived Cardiomyocytes Elucidate Single-Cell Phenotype of Brugada Syndrome. Journal of the American College of Cardiology. 68: 2086-2096. PMID 27810048 DOI: 10.1016/J.Jacc.2016.07.779 |
0.703 |
|
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