Hakon Leffler - Publications

Affiliations: 
1984-1990 University of California, San Diego, La Jolla, CA 

150 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Mahanti M, Pal KB, Sundin AP, Leffler H, Nilsson UJ. Epimers Switch Galectin-9 Domain Selectivity: 3-Aryl Galactosides Bind the C-Terminal and Gulosides Bind the N-Terminal. Acs Medicinal Chemistry Letters. 11: 34-39. PMID 31938460 DOI: 10.1021/Acsmedchemlett.9B00396  0.337
2019 Dahlqvist A, Mandal S, Peterson K, Håkansson M, Logan DT, Zetterberg FR, Leffler H, Nilsson UJ. 3-Substituted 1-Naphthamidomethyl-C-galactosyls Interact with Two Unique Sub-sites for High-Affinity and High-Selectivity Inhibition of Galectin-3. Molecules (Basel, Switzerland). 24. PMID 31842451 DOI: 10.3390/Molecules24244554  0.376
2019 Pal KB, Mahanti M, Leffler H, Nilsson UJ. A Galactoside-Binding Protein Tricked into Binding Unnatural Pyranose Derivatives: 3-Deoxy-3-Methyl-Gulosides Selectively Inhibit Galectin-1. International Journal of Molecular Sciences. 20. PMID 31382488 DOI: 10.3390/Ijms20153786  0.321
2019 Dahlqvist A, Zetterberg FR, Leffler H, Nilsson UJ. Aminopyrimidine-galactose hybrids are highly selective galectin-3 inhibitors. Medchemcomm. 10: 913-925. PMID 31303989 DOI: 10.1039/C9Md00183B  0.353
2019 Kumar R, Ignjatović MM, Peterson K, Olsson M, Leffler H, Ryde U, Nilsson UJ, Logan DT. Structure and energetics of ligand-fluorine interactions with galectin-3 backbone and side-chain amides - insight into solvation effects and multipolar interactions. Chemmedchem. PMID 31246331 DOI: 10.2210/Pdb6Qlo/Pdb  0.34
2019 Dahlqvist A, Furevi A, Warlin N, Leffler H, Nilsson UJ. Stereo- and regioselective hydroboration of 1--methylene pyranoses: discovery of aryltriazolylmethyl C-galactopyranosides as selective galectin-1 inhibitors. Beilstein Journal of Organic Chemistry. 15: 1046-1060. PMID 31164942 DOI: 10.3762/Bjoc.15.102  0.323
2019 Stegmayr J, Zetterberg F, Carlsson MC, Huang X, Sharma G, Kahl-Knutson B, Schambye H, Nilsson UJ, Oredsson S, Leffler H. Extracellular and intracellular small-molecule galectin-3 inhibitors. Scientific Reports. 9: 2186. PMID 30778105 DOI: 10.1038/S41598-019-38497-8  0.348
2019 Bojić-Trbojević Ž, Jovanović Krivokuća M, Vilotić A, Kolundžić N, Stefanoska I, Zetterberg F, Nilsson UJ, Leffler H, Vićovac L. Human trophoblast requires galectin-3 for cell migration and invasion. Scientific Reports. 9: 2136. PMID 30765738 DOI: 10.1038/S41598-018-38374-W  0.301
2019 Kumar R, Peterson K, Misini Ignjatović M, Leffler H, Ryde U, Nilsson UJ, Logan DT. Substituted polyfluoroaryl interactions with an arginine side chain in galectin-3 are governed by steric-, desolvation and electronic conjugation effects. Organic & Biomolecular Chemistry. PMID 30632578 DOI: 10.2210/Pdb6I76/Pdb  0.414
2019 Verteramo ML, Stenström O, Misini Ignjatovic M, Caldararu O, Olsson MA, Manzoni F, Leffler H, Oksanen E, Logan DT, Nilsson UJ, Ryde U, Akke M. Interplay between Conformational Entropy and Solvation Entropy in Protein-Ligand Binding. Journal of the American Chemical Society. PMID 30618244 DOI: 10.1021/Jacs.8B11099  0.34
2018 Ingemann Nielsen M, Stegmayr J, Grant OC, Yang Z, Nilsson UJ, Boos I, Carlsson MC, Woods RJ, Unverzagt C, Leffler H, Wandall HH. Galectin binding to cells and glycoproteins with genetically modified glycosylation reveals galectin-glycan specificities in a natural context. The Journal of Biological Chemistry. PMID 30385505 DOI: 10.1074/Jbc.Ra118.004636  0.432
2018 Pal KB, Mahanti M, Huang X, Persson S, Sundin AP, Zetterberg FR, Oredsson S, Leffler H, Nilsson UJ. Quinoline-galactose hybrids bind selectively with high affinity to a galectin-8 N-terminal domain. Organic & Biomolecular Chemistry. PMID 30117507 DOI: 10.1039/C8Ob01354C  0.367
2018 Johannes L, Jacob R, Leffler H. Galectins at a glance. Journal of Cell Science. 131. PMID 29717004 DOI: 10.1242/Jcs.208884  0.345
2018 Aanhane E, Schulkens IA, Heusschen R, Castricum K, Leffler H, Griffioen AW, Thijssen VL. Different angioregulatory activity of monovalent galectin-9 isoforms. Angiogenesis. PMID 29500586 DOI: 10.1007/S10456-018-9607-8  0.306
2018 Sundqvist M, Welin A, Elmwall J, Osla V, Nilsson UJ, Leffler H, Bylund J, Karlsson A. Galectin-3 type-C self-association on neutrophil surfaces; The carbohydrate recognition domain regulates cell function. Journal of Leukocyte Biology. PMID 29345346 DOI: 10.1002/Jlb.3A0317-110R  0.374
2018 Peterson K, Collins PM, Huang X, Kahl-Knutsson B, Essén S, Zetterberg FR, Oredsson S, Leffler H, Blanchard H, Nilsson UJ. Aromatic heterocycle galectin-1 interactions for selective single-digit nM affinity ligands Rsc Advances. 8: 24913-24922. DOI: 10.1039/C8Ra04389B  0.306
2017 Noresson AL, Aurelius O, Öberg CT, Engström O, Sundin AP, Håkansson M, Stenström O, Akke M, Logan DT, Leffler H, Nilsson UJ. Designing interactions by control of protein-ligand complex conformation: tuning arginine-arene interaction geometry for enhanced electrostatic protein-ligand interactions. Chemical Science. 9: 1014-1021. PMID 29675148 DOI: 10.1039/C7Sc04749E  0.352
2017 Peterson K, Kumar R, Stenström O, Verma P, Verma PR, Håkansson M, Kahl-Knutsson B, Zetterberg F, Leffler H, Akke M, Logan DT, Nilsson UJ. Systematic tuning of fluoro-galectin-3 interactions provides thiodigalactoside derivatives with single digit nM affinity and high selectivity. Journal of Medicinal Chemistry. PMID 29284090 DOI: 10.1021/Acs.Jmedchem.7B01626  0.338
2017 Zetterberg FR, Peterson K, Johnsson R, Brimert T, Håkansson M, Logan DT, Leffler H, Nilsson UJ. Monosaccharide derivatives with low nM lectin affinity and high selectivity based on combined fluorine-amide, phenyl-arginine, sulfur-π, and halogen bond interactions. Chemmedchem. PMID 29194992 DOI: 10.1002/Cmdc.201700744  0.36
2017 Magescas J, Sengmanivong L, Viau A, Mayeux A, Dang T, Burtin M, Nilsson UJ, Leffler H, Poirier F, Terzi F, Delacour D. Spindle pole cohesion requires glycosylation-mediated localization of NuMA. Scientific Reports. 7: 1474. PMID 28469279 DOI: 10.1038/S41598-017-01614-6  0.327
2016 Rajput VK, MacKinnon A, Mandal S, Collins P, Blanchard H, Leffler H, Sethi T, Schambye H, Mukhopadhyay B, Nilsson UJ. A selective galactose-coumarin-derived galectin-3 inhibitor demonstrates involvement of galectin-3-glycan interactions in a pulmonary fibrosis model. Journal of Medicinal Chemistry. PMID 27500311 DOI: 10.1021/Acs.Jmedchem.6B00957  0.31
2016 Delaine T, Collins P, Mac Kinnon A, Sharma G, Stegmayr J, Rajput VK, Mandal S, Cumpstey I, Larumbe A, Salameh BA, Kahl-Knutsson B, Van Hattum H, Van Scherpenzeel M, Pieters RJ, Sethi T, ... ... Leffler H, et al. Galectin-3-binding glycomimetics that strongly reduce bleomycin-induced lung fibrosis and modulate intracellular glycan recognition. Chembiochem : a European Journal of Chemical Biology. PMID 27356186 DOI: 10.1002/Cbic.201600285  0.379
2016 Stegmayr J, Lepur A, Kahl-Knutson B, Aguilar-Moncayo M, Klyosov AA, Field RA, Oredsson S, Nilsson UJ, Leffler H. Low or no inhibitory potency of the canonical galectin carbohydrate binding site by pectins and galactomannans. The Journal of Biological Chemistry. PMID 27129206 DOI: 10.1074/Jbc.M116.721464  0.374
2016 Ippel H, Miller MC, Vértesy S, Zhang Y, Cañada FJ, Suylen D, Umemoto K, Romanò C, Hackeng T, Tai G, Leffler H, Kopitz J, André S, Kübler D, Jiménez-Barbero J, et al. Intra- and inter-molecular interactions of human galectin-3: assessment by full-assignment-based NMR. Glycobiology. PMID 26911284 DOI: 10.1093/Glycob/Cww021  0.38
2016 Bum-Erdene K, Leffler H, Nilsson UJ, Blanchard H. Structural characterisation of human galectin-4 N-terminal carbohydrate recognition domain in complex with glycerol, lactose, 3'-sulfo-lactose, and 2'-fucosyllactose. Scientific Reports. 6: 20289. PMID 26828567 DOI: 10.1038/Srep20289  0.395
2016 Mandal S, Rajput VK, Sundin AP, Leffler H, Mukhopadhyay B, Nilsson UJ. Galactose-amidine derivatives as selective antagonists of galectin-9 Canadian Journal of Chemistry. 94: 936-939. DOI: 10.1139/Cjc-2015-0598  0.323
2015 Bum-Erdene K, Leffler H, Nilsson UJ, Blanchard H. Structural characterization of human galectin-4 C-terminal domain: elucidating the molecular basis for recognition of glycosphingolipids, sulfated saccharides and blood group antigens. The Febs Journal. PMID 26077389 DOI: 10.1111/Febs.13348  0.426
2015 Mackinnon A, Chen WS, Leffler H, Panjwani N, Schambye H, Sethi T, Nilsson UJ. Design, synthesis, And applications of galectin modulators in human health Topics in Medicinal Chemistry. 12: 95-122. DOI: 10.1007/7355_2014_49  0.386
2014 Rajput VK, Leffler H, Nilsson UJ, Mukhopadhyay B. Synthesis and evaluation of iminocoumaryl and coumaryl derivatized glycosides as galectin antagonists. Bioorganic & Medicinal Chemistry Letters. 24: 3516-20. PMID 24973029 DOI: 10.1016/J.Bmcl.2014.05.063  0.309
2014 von Mach T, Carlsson MC, Straube T, Nilsson U, Leffler H, Jacob R. Ligand binding and complex formation of galectin-3 is modulated by pH variations. The Biochemical Journal. 457: 107-15. PMID 24147723 DOI: 10.1042/Bj20130933  0.355
2013 Carlsson MC, Bengtson P, Cucak H, Leffler H. Galectin-3 guides intracellular trafficking of some human serotransferrin glycoforms. The Journal of Biological Chemistry. 288: 28398-408. PMID 23926108 DOI: 10.1074/Jbc.M113.487793  0.353
2013 Bum-Erdene K, Gagarinov IA, Collins PM, Winger M, Pearson AG, Wilson JC, Leffler H, Nilsson UJ, Grice ID, Blanchard H. Investigation into the feasibility of thioditaloside as a novel scaffold for galectin-3-specific inhibitors. Chembiochem : a European Journal of Chemical Biology. 14: 1331-42. PMID 23864426 DOI: 10.1002/Cbic.201300245  0.379
2013 van Hattum H, Branderhorst HM, Moret EE, Nilsson UJ, Leffler H, Pieters RJ. Tuning the preference of thiodigalactoside- and lactosamine-based ligands to galectin-3 over galectin-1. Journal of Medicinal Chemistry. 56: 1350-4. PMID 23281927 DOI: 10.1021/Jm301677R  0.31
2012 Breimer ME, Hansson GC, Karlsson KA, Larson G, Leffler H. Glycosphingolipid composition of epithelial cells isolated along the villus axis of small intestine of a single human individual. Glycobiology. 22: 1721-30. PMID 22833314 DOI: 10.1093/Glycob/Cws115  0.337
2012 Lepur A, Salomonsson E, Nilsson UJ, Leffler H. Ligand induced galectin-3 protein self-association. The Journal of Biological Chemistry. 287: 21751-6. PMID 22549776 DOI: 10.1074/Jbc.C112.358002  0.357
2012 Carlsson MC, Balog CI, Kilsgård O, Hellmark T, Bakoush O, Segelmark M, Fernö M, Olsson H, Malmström J, Wuhrer M, Leffler H. Different fractions of human serum glycoproteins bind galectin-1 or galectin-8, and their ratio may provide a refined biomarker for pathophysiological conditions in cancer and inflammatory disease. Biochimica Et Biophysica Acta. 1820: 1366-72. PMID 22285770 DOI: 10.1016/J.Bbagen.2012.01.007  0.309
2012 Cederfur C, Malmström J, Nihlberg K, Block M, Breimer ME, Bjermer L, Westergren-Thorsson G, Leffler H. Glycoproteomic identification of galectin-3 and -8 ligands in bronchoalveolar lavage of mild asthmatics and healthy subjects. Biochimica Et Biophysica Acta. 1820: 1429-36. PMID 22240167 DOI: 10.1016/J.Bbagen.2011.12.016  0.319
2012 Carlsson MC, Bakoush O, Tengroth L, Kilsgård O, Malmström J, Hellmark T, Segelmark M, Leffler H. Galectin-8 in IgA nephritis: decreased binding of IgA by galectin-8 affinity chromatography and associated increased binding in non-IgA serum glycoproteins. Journal of Clinical Immunology. 32: 246-55. PMID 22173878 DOI: 10.1007/S10875-011-9618-3  0.327
2012 Collins PM, Oberg CT, Leffler H, Nilsson UJ, Blanchard H. Taloside inhibitors of galectin-1 and galectin-3. Chemical Biology & Drug Design. 79: 339-46. PMID 22136701 DOI: 10.1111/J.1747-0285.2011.01283.X  0.347
2012 Saraboji K, HÃ¥kansson M, Genheden S, Diehl C, Qvist J, Weininger U, Nilsson UJ, Leffler H, Ryde U, Akke M, Logan DT. The carbohydrate-binding site in galectin-3 is preorganized to recognize a sugarlike framework of oxygens: ultra-high-resolution structures and water dynamics. Biochemistry. 51: 296-306. PMID 22111949 DOI: 10.1021/Bi201459P  0.352
2012 Masuyer G, Jabeen T, Öberg CT, Leffler H, Nilsson UJ, Acharya KR. Inhibition mechanism of human galectin-7 by a novel galactose-benzylphosphate inhibitor. The Febs Journal. 279: 193-202. PMID 22059385 DOI: 10.1111/J.1742-4658.2011.08414.X  0.374
2011 Carlsson MC, Cederfur C, Schaar V, Balog CI, Lepur A, Touret F, Salomonsson E, Deelder AM, Fernö M, Olsson H, Wuhrer M, Leffler H. Galectin-1-binding glycoforms of haptoglobin with altered intracellular trafficking, and increase in metastatic breast cancer patients. Plos One. 6: e26560. PMID 22028908 DOI: 10.1371/Journal.Pone.0026560  0.375
2011 Öberg CT, Noresson AL, Leffler H, Nilsson UJ. Arene-anion based arginine-binding motif on a galactose scaffold: structure-activity relationships of interactions with arginine-rich galectins. Chemistry (Weinheim An Der Bergstrasse, Germany). 17: 8139-44. PMID 21656580 DOI: 10.1002/Chem.201003247  0.315
2011 Oberg CT, Leffler H, Nilsson UJ. Inhibition of galectins with small molecules. Chimia. 65: 18-23. PMID 21469439 DOI: 10.2533/Chimia.2011.18  0.398
2011 Salomonsson E, Thijssen VL, Griffioen AW, Nilsson UJ, Leffler H. The anti-angiogenic peptide anginex greatly enhances galectin-1 binding affinity for glycoproteins. The Journal of Biological Chemistry. 286: 13801-4. PMID 21372130 DOI: 10.1074/Jbc.C111.229096  0.353
2010 Diehl C, Engström O, Delaine T, Håkansson M, Genheden S, Modig K, Leffler H, Ryde U, Nilsson UJ, Akke M. Protein flexibility and conformational entropy in ligand design targeting the carbohydrate recognition domain of galectin-3. Journal of the American Chemical Society. 132: 14577-89. PMID 20873837 DOI: 10.1021/Ja105852Y  0.388
2010 Salomonsson E, Larumbe A, Tejler J, Tullberg E, Rydberg H, Sundin A, Khabut A, Frejd T, Lobsanov YD, Rini JM, Nilsson UJ, Leffler H. Monovalent interactions of galectin-1. Biochemistry. 49: 9518-32. PMID 20873803 DOI: 10.1021/Bi1009584  0.403
2010 Stannard KA, Collins PM, Ito K, Sullivan EM, Scott SA, Gabutero E, Darren Grice I, Low P, Nilsson UJ, Leffler H, Blanchard H, Ralph SJ. Galectin inhibitory disaccharides promote tumour immunity in a breast cancer model. Cancer Letters. 299: 95-110. PMID 20826047 DOI: 10.1016/J.Canlet.2010.08.005  0.301
2010 Salomonsson E, Carlsson MC, Osla V, Hendus-Altenburger R, Kahl-Knutson B, Oberg CT, Sundin A, Nilsson R, Nordberg-Karlsson E, Nilsson UJ, Karlsson A, Rini JM, Leffler H. Mutational tuning of galectin-3 specificity and biological function. The Journal of Biological Chemistry. 285: 35079-91. PMID 20807768 DOI: 10.1074/Jbc.M109.098160  0.398
2010 Gouin SG, García Fernández JM, Vanquelef E, Dupradeau FY, Salomonsson E, Leffler H, Ortega-Muñoz M, Nilsson UJ, Kovensky J. Multimeric lactoside "click clusters" as tools to investigate the effect of linker length in specific interactions with peanut lectin, galectin-1, and -3. Chembiochem : a European Journal of Chemical Biology. 11: 1430-42. PMID 20549756 DOI: 10.1002/Cbic.201000167  0.375
2010 Salameh BA, Cumpstey I, Sundin A, Leffler H, Nilsson UJ. 1H-1,2,3-triazol-1-yl thiodigalactoside derivatives as high affinity galectin-3 inhibitors. Bioorganic & Medicinal Chemistry. 18: 5367-78. PMID 20538469 DOI: 10.1016/J.Bmc.2010.05.040  0.32
2010 Paz I, Sachse M, Dupont N, Mounier J, Cederfur C, Enninga J, Leffler H, Poirier F, Prevost MC, Lafont F, Sansonetti P. Galectin-3, a marker for vacuole lysis by invasive pathogens. Cellular Microbiology. 12: 530-44. PMID 19951367 DOI: 10.1111/J.1462-5822.2009.01415.X  0.404
2009 Tejler J, Salameh B, Leffler H, Nilsson UJ. Fragment-based development of triazole-substituted O-galactosyl aldoximes with fragment-induced affinity and selectivity for galectin-3. Organic & Biomolecular Chemistry. 7: 3982-90. PMID 19763301 DOI: 10.1039/B909091F  0.332
2009 van Scherpenzeel M, Moret EE, Ballell L, Liskamp RM, Nilsson UJ, Leffler H, Pieters RJ. Synthesis and evaluation of new thiodigalactoside-based chemical probes to label galectin-3. Chembiochem : a European Journal of Chemical Biology. 10: 1724-33. PMID 19492387 DOI: 10.1002/Cbic.200900198  0.345
2009 Jendholm J, Mörgelin M, Perez Vidakovics ML, Carlsson M, Leffler H, Cardell LO, Riesbeck K. Superantigen- and TLR-dependent activation of tonsillar B cells after receptor-mediated endocytosis. Journal of Immunology (Baltimore, Md. : 1950). 182: 4713-20. PMID 19342647 DOI: 10.4049/Jimmunol.0803032  0.304
2009 Diskin S, Cao Z, Leffler H, Panjwani N. The role of integrin glycosylation in galectin-8-mediated trabecular meshwork cell adhesion and spreading. Glycobiology. 19: 29-37. PMID 18849583 DOI: 10.1093/Glycob/Cwn100  0.347
2009 Karlsson A, Christenson K, Matlak M, Björstad A, Brown KL, Telemo E, Salomonsson E, Leffler H, Bylund J. Galectin-3 functions as an opsonin and enhances the macrophage clearance of apoptotic neutrophils. Glycobiology. 19: 16-20. PMID 18849325 DOI: 10.1093/Glycob/Cwn104  0.346
2008 Delaine T, Cumpstey I, Ingrassia L, Le Mercier M, Okechukwu P, Leffler H, Kiss R, Nilsson UJ. Galectin-inhibitory thiodigalactoside ester derivatives have antimigratory effects in cultured lung and prostate cancer cells. Journal of Medicinal Chemistry. 51: 8109-14. PMID 19053747 DOI: 10.1021/Jm801077J  0.313
2008 Forsman H, Salomonsson E, Onnheim K, Karlsson J, Björstad A, Leffler H, Bylund J, Karlsson A, Dahlgren C. The beta-galactoside binding immunomodulatory lectin galectin-3 reverses the desensitized state induced in neutrophils by the chemotactic peptide f-Met-Leu-Phe: role of reactive oxygen species generated by the NADPH-oxidase and inactivation of the agonist. Glycobiology. 18: 905-12. PMID 18725453 DOI: 10.1093/Glycob/Cwn081  0.375
2008 Oberg CT, Blanchard H, Leffler H, Nilsson UJ. Protein subtype-targeting through ligand epimerization: talose-selectivity of galectin-4 and galectin-8. Bioorganic & Medicinal Chemistry Letters. 18: 3691-4. PMID 18539029 DOI: 10.1016/J.Bmcl.2008.05.066  0.332
2008 Cumpstey I, Salomonsson E, Sundin A, Leffler H, Nilsson UJ. Double affinity amplification of galectin-ligand interactions through arginine-arene interactions: synthetic, thermodynamic, and computational studies with aromatic diamido thiodigalactosides. Chemistry (Weinheim An Der Bergstrasse, Germany). 14: 4233-45. PMID 18366047 DOI: 10.1002/Chem.200701932  0.39
2008 Oberg CT, Leffler H, Nilsson UJ. Arginine binding motifs: design and synthesis of galactose-derived arginine tweezers as galectin-3 inhibitors. Journal of Medicinal Chemistry. 51: 2297-301. PMID 18318467 DOI: 10.1021/Jm701266Y  0.314
2008 Stowell SR, Qian Y, Karmakar S, Koyama NS, Dias-Baruffi M, Leffler H, McEver RP, Cummings RD. Differential roles of galectin-1 and galectin-3 in regulating leukocyte viability and cytokine secretion. Journal of Immunology (Baltimore, Md. : 1950). 180: 3091-102. PMID 18292532 DOI: 10.4049/Jimmunol.180.5.3091  0.314
2008 Cederfur C, Salomonsson E, Nilsson J, Halim A, Oberg CT, Larson G, Nilsson UJ, Leffler H. Different affinity of galectins for human serum glycoproteins: galectin-3 binds many protease inhibitors and acute phase proteins. Glycobiology. 18: 384-94. PMID 18263896 DOI: 10.1093/Glycob/Cwn015  0.385
2008 Stowell SR, Arthur CM, Mehta P, Slanina KA, Blixt O, Leffler H, Smith DF, Cummings RD. Galectin-1, -2, and -3 exhibit differential recognition of sialylated glycans and blood group antigens. The Journal of Biological Chemistry. 283: 10109-23. PMID 18216021 DOI: 10.1074/Jbc.M709545200  0.426
2007 Bax M, García-Vallejo JJ, Jang-Lee J, North SJ, Gilmartin TJ, Hernández G, Crocker PR, Leffler H, Head SR, Haslam SM, Dell A, van Kooyk Y. Dendritic cell maturation results in pronounced changes in glycan expression affecting recognition by siglecs and galectins. Journal of Immunology (Baltimore, Md. : 1950). 179: 8216-24. PMID 18056365 DOI: 10.4049/Jimmunol.179.12.8216  0.334
2007 Cumpstey I, Salomonsson E, Sundin A, Leffler H, Nilsson UJ. Studies of arginine-arene interactions through synthesis and evaluation of a series of galectin-binding aromatic lactose esters. Chembiochem : a European Journal of Chemical Biology. 8: 1389-98. PMID 17631664 DOI: 10.1002/Cbic.200700040  0.371
2007 Carlsson S, Carlsson MC, Leffler H. Intracellular sorting of galectin-8 based on carbohydrate fine specificity. Glycobiology. 17: 906-12. PMID 17580315 DOI: 10.1093/Glycob/Cwm059  0.381
2007 Gustavsson P, Linsmeier CE, Leffler H, Kanje M. Galectin-3 inhibits Schwann cell proliferation in cultured sciatic nerve. Neuroreport. 18: 669-73. PMID 17426596 DOI: 10.1097/Wnr.0B013E3280Bef97B  0.318
2007 Tejler J, Skogman F, Leffler H, Nilsson UJ. Synthesis of galactose-mimicking 1H-(1,2,3-triazol-1-yl)-mannosides as selective galectin-3 and 9N inhibitors. Carbohydrate Research. 342: 1869-75. PMID 17407769 DOI: 10.1016/J.Carres.2007.03.012  0.34
2007 Carlsson S, Oberg CT, Carlsson MC, Sundin A, Nilsson UJ, Smith D, Cummings RD, Almkvist J, Karlsson A, Leffler H. Affinity of galectin-8 and its carbohydrate recognition domains for ligands in solution and at the cell surface. Glycobiology. 17: 663-76. PMID 17339281 DOI: 10.1093/Glycob/Cwm026  0.423
2007 Delacour D, Greb C, Koch A, Salomonsson E, Leffler H, Le Bivic A, Jacob R. Apical sorting by galectin-3-dependent glycoprotein clustering. Traffic (Copenhagen, Denmark). 8: 379-88. PMID 17319896 DOI: 10.1111/J.1600-0854.2007.00539.X  0.321
2006 Zhuang T, Leffler H, Prestegard JH. Enhancement of bound-state residual dipolar couplings: conformational analysis of lactose bound to Galectin-3. Protein Science : a Publication of the Protein Society. 15: 1780-90. PMID 16751604 DOI: 10.1110/Ps.051994306  0.346
2006 Tejler J, Tullberg E, Frejd T, Leffler H, Nilsson UJ. Synthesis of multivalent lactose derivatives by 1,3-dipolar cycloadditions: selective galectin-1 inhibition. Carbohydrate Research. 341: 1353-62. PMID 16697988 DOI: 10.1016/J.Carres.2006.04.028  0.324
2006 Patnaik SK, Potvin B, Carlsson S, Sturm D, Leffler H, Stanley P. Complex N-glycans are the major ligands for galectin-1, -3, and -8 on Chinese hamster ovary cells. Glycobiology. 16: 305-17. PMID 16319083 DOI: 10.1093/Glycob/Cwj063  0.45
2005 Cumpstey I, Sundin A, Leffler H, Nilsson UJ. C2-symmetrical thiodigalactoside bis-benzamido derivatives as high-affinity inhibitors of galectin-3: efficient lectin inhibition through double arginine-arene interactions. Angewandte Chemie (International Ed. in English). 44: 5110-2. PMID 16007713 DOI: 10.1002/Anie.200500627  0.321
2005 Cumpstey I, Carlsson S, Leffler H, Nilsson UJ. Synthesis of a phenyl thio-beta-D-galactopyranoside library from 1,5-difluoro-2,4-dinitrobenzene: discovery of efficient and selective monosaccharide inhibitors of galectin-7. Organic & Biomolecular Chemistry. 3: 1922-32. PMID 15889175 DOI: 10.1039/B502354H  0.334
2005 Sörme P, Arnoux P, Kahl-Knutsson B, Leffler H, Rini JM, Nilsson UJ. Structural and thermodynamic studies on cation-Pi interactions in lectin-ligand complexes: high-affinity galectin-3 inhibitors through fine-tuning of an arginine-arene interaction. Journal of the American Chemical Society. 127: 1737-43. PMID 15701008 DOI: 10.1021/Ja043475P  0.391
2004 Sörme P, Kahl-Knutsson B, Huflejt M, Nilsson UJ, Leffler H. Fluorescence polarization as an analytical tool to evaluate galectin-ligand interactions. Analytical Biochemistry. 334: 36-47. PMID 15464951 DOI: 10.1016/J.Ab.2004.06.042  0.376
2004 Almkvist J, Dahlgren C, Leffler H, Karlsson A. Newcastle disease virus neuraminidase primes neutrophils for stimulation by galectin-3 and formyl-Met-Leu-Phe. Experimental Cell Research. 298: 74-82. PMID 15242763 DOI: 10.1016/J.Yexcr.2004.04.006  0.33
2004 Huflejt ME, Leffler H. Galectin-4 in normal tissues and cancer. Glycoconjugate Journal. 20: 247-55. PMID 15115909 DOI: 10.1023/B:Glyc.0000025819.54723.A0  0.368
2004 Houzelstein D, Gonçalves IR, Fadden AJ, Sidhu SS, Cooper DN, Drickamer K, Leffler H, Poirier F. Phylogenetic analysis of the vertebrate galectin family. Molecular Biology and Evolution. 21: 1177-87. PMID 14963092 DOI: 10.1093/Molbev/Msh082  0.529
2003 Sörme P, Kahl-Knutsson B, Wellmar U, Magnusson BG, Leffler H, Nilsson UJ. Design and synthesis of galectin inhibitors. Methods in Enzymology. 363: 157-69. PMID 14579574 DOI: 10.1016/S0076-6879(03)01050-4  0.395
2003 Sörme P, Kahl-Knutson B, Wellmar U, Nilsson UJ, Leffler H. Fluorescence polarization to study galectin-ligand interactions. Methods in Enzymology. 362: 504-12. PMID 12968384 DOI: 10.1016/S0076-6879(03)01033-4  0.369
2003 Umemoto K, Leffler H, Venot A, Valafar H, Prestegard JH. Conformational differences in liganded and unliganded states of Galectin-3. Biochemistry. 42: 3688-95. PMID 12667058 DOI: 10.1021/Bi026671M  0.37
2002 John CM, Jarvis GA, Swanson KV, Leffler H, Cooper MD, Huflejt ME, Griffiss JM. Galectin-3 binds lactosaminylated lipooligosaccharides from Neisseria gonorrhoeae and is selectively expressed by mucosal epithelial cells that are infected. Cellular Microbiology. 4: 649-62. PMID 12366402 DOI: 10.1046/J.1462-5822.2002.00219.X  0.424
2002 Almkvist J, Dahlgren C, Leffler H, Karlsson A. Activation of the neutrophil nicotinamide adenine dinucleotide phosphate oxidase by galectin-1. Journal of Immunology (Baltimore, Md. : 1950). 168: 4034-41. PMID 11937561 DOI: 10.4049/Jimmunol.168.8.4034  0.382
2002 Sörme P, Qian Y, Nyholm PG, Leffler H, Nilsson UJ. Low micromolar inhibitors of galectin-3 based on 3'-derivatization of N-acetyllactosamine. Chembiochem : a European Journal of Chemical Biology. 3: 183-9. PMID 11921396 DOI: 10.1002/1439-7633(20020301)3:2/3<183::Aid-Cbic183>3.0.Co;2-#  0.315
2002 Thomsson KA, Prakobphol A, Leffler H, Reddy MS, Levine MJ, Fisher SJ, Hansson GC. The salivary mucin MG1 (MUC5B) carries a repertoire of unique oligosaccharides that is large and diverse. Glycobiology. 12: 1-14. PMID 11825880 DOI: 10.1093/Glycob/12.1.1  0.342
2001 Jain NU, Venot A, Umemoto K, Leffler H, Prestegard JH. Distance mapping of protein-binding sites using spin-labeled oligosaccharide ligands. Protein Science : a Publication of the Protein Society. 10: 2393-400. PMID 11604544 DOI: 10.1110/Ps.17401  0.346
2001 Capon C, Maes E, Michalski JC, Leffler H, Kim YS. Sd(a)-antigen-like structures carried on core 3 are prominent features of glycans from the mucin of normal human descending colon. The Biochemical Journal. 358: 657-64. PMID 11577689 DOI: 10.1042/Bj3580657  0.307
2001 Leffler H. Galectins structure and function--a synopsis. Results and Problems in Cell Differentiation. 33: 57-83. PMID 11190679 DOI: 10.1007/978-3-540-46410-5_4  0.331
2001 Almkvist J, Fäldt J, Dahlgren C, Leffler H, Karlsson A. Lipopolysaccharide-induced gelatinase granule mobilization primes neutrophils for activation by galectin-3 and formylmethionyl-Leu-Phe. Infection and Immunity. 69: 832-7. PMID 11159975 DOI: 10.1128/Iai.69.2.832-837.2001  0.301
2000 Prakobphol A, Xu F, Hoang VM, Larsson T, Bergstrom J, Johansson I, Frängsmyr L, Holmskov U, Leffler H, Nilsson C, Borén T, Wright JR, Strömberg N, Fisher SJ. Salivary agglutinin, which binds Streptococcus mutans and Helicobacter pylori, is the lung scavenger receptor cysteine-rich protein gp-340. The Journal of Biological Chemistry. 275: 39860-6. PMID 11007786 DOI: 10.1074/Jbc.M006928200  0.337
1999 Prakobphol A, Tangemann K, Rosen SD, Hoover CI, Leffler H, Fisher SJ. Separate oligosaccharide determinants mediate interactions of the low-molecular-weight salivary mucin with neutrophils and bacteria. Biochemistry. 38: 6817-25. PMID 10346903 DOI: 10.1021/Bi990145M  0.545
1998 Seetharaman J, Kanigsberg A, Slaaby R, Leffler H, Barondes SH, Rini JM. X-ray crystal structure of the human galectin-3 carbohydrate recognition domain at 2.1-A resolution. The Journal of Biological Chemistry. 273: 13047-52. PMID 9582341 DOI: 10.1074/Jbc.273.21.13047  0.599
1998 Karlsson A, Follin P, Leffler H, Dahlgren C. Galectin-3 activates the NADPH-oxidase in exudated but not peripheral blood neutrophils. Blood. 91: 3430-8. PMID 9558402 DOI: 10.1182/Blood.V91.9.3430.3430_3430_3438  0.357
1998 Prakobphol A, Thomsson KA, Hansson GC, Rosen SD, Singer MS, Phillips NJ, Medzihradszky KF, Burlingame AL, Leffler H, Fisher SJ. Human low-molecular-weight salivary mucin expresses the sialyl lewisx determinant and has L-selectin ligand activity. Biochemistry. 37: 4916-27. PMID 9538010 DOI: 10.1021/Bi972612A  0.575
1998 Gitt MA, Xia YR, Atchison RE, Lusis AJ, Barondes SH, Leffler H. Sequence, structure, and chromosomal mapping of the mouse Lgals6 gene, encoding galectin-6. The Journal of Biological Chemistry. 273: 2961-70. PMID 9446609 DOI: 10.1074/Jbc.273.5.2961  0.526
1998 Gitt MA, Colnot C, Poirier F, Nani KJ, Barondes SH, Leffler H. Galectin-4 and galectin-6 are two closely related lectins expressed in mouse gastrointestinal tract. The Journal of Biological Chemistry. 273: 2954-60. PMID 9446608 DOI: 10.1074/Jbc.273.5.2954  0.58
1997 Capon C, Wieruszeski JM, Lemoine J, Byrd JC, Leffler H, Kim YS. Sulfated lewis X determinants as a major structural motif in glycans from LS174T-HM7 human colon carcinoma mucin. The Journal of Biological Chemistry. 272: 31957-68. PMID 9405387 DOI: 10.1074/Jbc.272.51.31957  0.307
1997 Prakobphol A, Leffler H, Hoover CI, Fisher SJ. Palmitoyl carnitine, a lysophospholipase-transacylase inhibitor, prevents Candida adherence in vitro. Fems Microbiology Letters. 151: 89-94. PMID 9198287 DOI: 10.1111/J.1574-6968.1997.Tb10399.X  0.332
1997 Huflejt ME, Jordan ET, Gitt MA, Barondes SH, Leffler H. Strikingly different localization of galectin-3 and galectin-4 in human colon adenocarcinoma T84 cells. Galectin-4 is localized at sites of cell adhesion. The Journal of Biological Chemistry. 272: 14294-303. PMID 9162064 DOI: 10.1074/Jbc.272.22.14294  0.595
1996 Mey A, Leffler H, Hmama Z, Normier G, Revillard JP. The animal lectin galectin-3 interacts with bacterial lipopolysaccharides via two independent sites. Journal of Immunology (Baltimore, Md. : 1950). 156: 1572-7. PMID 8568262  0.308
1996 Rini JM, Kanigsberg AI, Seetharaman J, Kayden CS, Leffler H, Barondes SH. X-ray crystal structures of galectins and their carbohydrate complexes Acta Crystallographica Section a Foundations of Crystallography. 52: C192-C192. DOI: 10.1107/S0108767396091659  0.442
1995 Leonidas DD, Elbert BL, Zhou Z, Leffler H, Ackerman SJ, Acharya KR. Crystal structure of human Charcot-Leyden crystal protein, an eosinophil lysophospholipase, identifies it as a new member of the carbohydrate-binding family of galectins. Structure (London, England : 1993). 3: 1379-93. PMID 8747464 DOI: 10.1016/S0969-2126(01)00275-1  0.304
1995 Gitt MA, Wiser MF, Leffler H, Herrmann J, Xia YR, Massa SM, Cooper DN, Lusis AJ, Barondes SH. Sequence and mapping of galectin-5, a beta-galactoside-binding lectin, found in rat erythrocytes. The Journal of Biological Chemistry. 270: 5032-8. PMID 7890611 DOI: 10.1074/Jbc.270.10.5032  0.662
1995 Hemmerich S, Leffler H, Rosen SD. Structure of the O-glycans in GlyCAM-1, an endothelial-derived ligand for L-selectin. The Journal of Biological Chemistry. 270: 12035-47. PMID 7538131 DOI: 10.1074/Jbc.270.20.12035  0.586
1995 Leffler H, Agace W, Hedges S, Lindstedt R, Svensson M, Svanborg C. Strategies for studying bacterial adhesion in vivo Methods in Enzymology. 253: 206-220. PMID 7476387 DOI: 10.1016/S0076-6879(95)53020-7  0.346
1995 Prakobphol A, Leffler H, Fisher SJ. Identifying bacterial receptor proteins and quantifying strength of interactions they mediate Methods in Enzymology. 253: 132-142. PMID 7476382 DOI: 10.1016/S0076-6879(95)53014-2  0.339
1994 Barondes SH, Cooper DN, Gitt MA, Leffler H. Galectins. Structure and function of a large family of animal lectins. The Journal of Biological Chemistry. 269: 20807-10. PMID 8063692  0.581
1994 Mandrell RE, Apicella MA, Lindstedt R, Leffler H. Possible interaction between animal lectins and bacterial carbohydrates Methods in Enzymology. 236: 231-254. PMID 7968613 DOI: 10.1016/0076-6879(94)36019-7  0.327
1994 Hemmerich S, Bertozzi CR, Leffler H, Rosen SD. Identification of the sulfated monosaccharides of GlyCAM-1, an endothelial-derived ligand for L-selectin. Biochemistry. 33: 4820-9. PMID 7512827 DOI: 10.1021/Bi00182A010  0.581
1993 Lindstedt R, Apodaca G, Barondes SH, Mostov KE, Leffler H. Apical secretion of a cytosolic protein by Madin-Darby canine kidney cells. Evidence for polarized release of an endogenous lectin by a nonclassical secretory pathway. The Journal of Biological Chemistry. 268: 11750-7. PMID 8505302  0.499
1993 Oda Y, Herrmann J, Gitt MA, Turck CW, Burlingame AL, Barondes SH, Leffler H. Soluble lactose-binding lectin from rat intestine with two different carbohydrate-binding domains in the same peptide chain. The Journal of Biological Chemistry. 268: 5929-39. PMID 8449956  0.554
1993 Mehrabian M, Gitt MA, Sparkes RS, Leffler H, Barondes SH, Lusis AJ. Two members of the S-lac lectin gene family, LGALS1 and LGALS2, reside in close proximity on human chromosome 22q12-q13. Genomics. 15: 418-20. PMID 8449510 DOI: 10.1006/Geno.1993.1078  0.538
1993 Massa SM, Cooper DN, Leffler H, Barondes SH. L-29, an endogenous lectin, binds to glycoconjugate ligands with positive cooperativity. Biochemistry. 32: 260-7. PMID 8418845 DOI: 10.1021/Bi00052A033  0.669
1993 Lobsanov YD, Gitt MA, Leffler H, Barondes S, Rini JM. Crystallization and preliminary X-ray diffraction analysis of the human dimeric S-Lac lectin (L-14-II). Journal of Molecular Biology. 233: 553-5. PMID 8411163 DOI: 10.1006/Jmbi.1993.1533  0.522
1993 Lobsanov YD, Gitt MA, Leffler H, Barondes SH, Rini JM. X-ray crystal structure of the human dimeric S-Lac lectin, L-14-II, in complex with lactose at 2.9-A resolution. The Journal of Biological Chemistry. 268: 27034-8. PMID 8262940 DOI: 10.2210/Pdb1Hlc/Pdb  0.603
1993 Huflejt ME, Turck CW, Lindstedt R, Barondes SH, Leffler H. L-29, a soluble lactose-binding lectin, is phosphorylated on serine 6 and serine 12 in vivo and by casein kinase I. The Journal of Biological Chemistry. 268: 26712-8. PMID 8253806  0.493
1993 Herrmann J, Turck CW, Atchison RE, Huflejt ME, Poulter L, Gitt MA, Burlingame AL, Barondes SH, Leffler H. Primary structure of the soluble lactose binding lectin L-29 from rat and dog and interaction of its non-collagenous proline-, glycine-, tyrosine-rich sequence with bacterial and tissue collagenase. The Journal of Biological Chemistry. 268: 26704-11. PMID 8253805  0.525
1992 Marschal P, Herrmann J, Leffler H, Barondes SH, Cooper DN. Sequence and specificity of a soluble lactose-binding lectin from Xenopus laevis skin. The Journal of Biological Chemistry. 267: 12942-9. PMID 1618791  0.645
1992 Gitt MA, Massa SM, Leffler H, Barondes SH. Isolation and expression of a gene encoding L-14-II, a new human soluble lactose-binding lectin. The Journal of Biological Chemistry. 267: 10601-6. PMID 1375225  0.528
1991 Oda Y, Leffler H, Sakakura Y, Kasai K, Barondes SH. Human breast carcinoma cDNA encoding a galactoside-binding lectin homologous to mouse Mac-2 antigen. Gene. 99: 279-83. PMID 2022338 DOI: 10.1016/0378-1119(91)90139-3  0.621
1991 Rafiee P, Leffler H, Byrd JC, Cassels FJ, Boedeker EC, Kim YS. A sialoglycoprotein complex linked to the microvillus cytoskeleton acts as a receptor for pilus (AF/R1) mediated adhesion of enteropathogenic Escherichia coli (RDEC-1) in rabbit small intestine Journal of Cell Biology. 115: 1021-1029. PMID 1683351 DOI: 10.1083/Jcb.115.4.1021  0.311
1991 Lindstedt R, Larson G, Falk P, Jodal U, Leffler H, Svanborg C. The receptor repertoir defines the host range for attaching Escherichia coli strains that recognize globo-A Infection and Immunity. 59: 1086-1092. PMID 1671774 DOI: 10.1128/Iai.59.3.1086-1092.1991  0.32
1990 Leffler H, Svanborg-Eden C. Host epithelial glycoconjugates and pathogenic bacteria American Journal of Respiratory Cell and Molecular Biology. 2: 409-411. PMID 2187491 DOI: 10.1165/Ajrcmb/2.5.409  0.352
1990 Baker N, Hansson GC, Leffler H, Riise G, Svanborg-Eden C. Glycosphingolipid receptors for Pseudomonas aeruginosa Infection and Immunity. 58: 2361-2366. PMID 2114364 DOI: 10.1128/Iai.58.7.2361-2366.1990  0.404
1989 Leffler H, Masiarz FR, Barondes SH. Soluble lactose-binding vertebrate lectins: a growing family. Biochemistry. 28: 9222-9. PMID 2605254 DOI: 10.1021/Bi00449A039  0.614
1989 Lindstedt R, Baker N, Falk P, Hull R, Hull S, Karr J, Leffler H, Svanborg Edén C, Larson G. Binding specificities of wild-type and cloned Escherichia coli strains that recognize globo-A. Infection and Immunity. 57: 3389-94. PMID 2572551 DOI: 10.1128/Iai.57.11.3389-3394.1989  0.366
1988 Barondes SH, Gitt MA, Leffler H, Cooper DN. Multiple soluble vertebrate galactoside-binding lectins. Biochimie. 70: 1627-32. PMID 3149527 DOI: 10.1016/0300-9084(88)90298-2  0.695
1987 Barondes SH, Leffler H. Soluble lactose-binding lectins from chicken and rat. Methods in Enzymology. 138: 510-5. PMID 3600343 DOI: 10.1016/0076-6879(87)38044-9  0.578
1987 Enerback S, Larsson AC, Leffler H, Lundell A, de Man P, Nilsson B, Svanborg-Edén C. Binding to galactoseα1→4galactoseβ-containing receptors as potential diagnostic tool in urinary tract infection Journal of Clinical Microbiology. 25: 407-411. PMID 2880868 DOI: 10.1128/Jcm.25.2.407-411.1987  0.361
1987 de Man P, Cedergren B, Enerback S, Larsson AC, Leffler H, Lundell AL, Nilsson B, Svanborg-Edén C. Receptor-specific agglutination tests for detection of bacteria that bind globoseries glycolipids Journal of Clinical Microbiology. 25: 401-406. PMID 2880867 DOI: 10.1128/Jcm.25.2.401-406.1987  0.331
1987 Sparrow CP, Leffler H, Barondes SH. Multiple soluble beta-galactoside-binding lectins from human lung. The Journal of Biological Chemistry. 262: 7383-90. PMID 2438278  0.556
1986 Leffler H, Barondes SH. Specificity of binding of three soluble rat lung lectins to substituted and unsubstituted mammalian beta-galactosides. The Journal of Biological Chemistry. 261: 10119-26. PMID 3733704  0.568
1986 Lomberg H, Cedergren B, Leffler H, Nilsson B, Carlström AS, Svanborg-Edén C. Influence of blood group on the availability of receptors for attachment of uropathogenic Escherichia coli Infection and Immunity. 51: 919-926. PMID 2868993 DOI: 10.1128/Iai.51.3.919-926.1986  0.324
1985 Breimer ME, Hansson GC, Leffler H. The specific glycosphingolipid composition of human ureteral epithelial cells Journal of Biochemistry. 98: 1169-1180. PMID 4086474 DOI: 10.1093/Oxfordjournals.Jbchem.A135383  0.338
1984 Andersson B, Fogh A, Jørgensen F, Larsson S, Leffler H, Magnusson G, Nylén O, Südow C, Svanborg Edén C. Attachment of Streptococcus pneumoniae to human pharyngeal epithelial cells in vitro - mechanism of binding Otolaryngology - Head and Neck Surgery. 92: 266-269. PMID 6431363 DOI: 10.1177/019459988409200304  0.385
1984 Svanborg Edén C, Bjursten LM, Hull R, Hull S, Magnusson KE, Moldovano Z, Leffler H. Influence of adhesins on the interaction of Escherichia coli with human phagocytes. Infection and Immunity. 44: 672-680. DOI: 10.1128/Iai.44.3.672-680.1984  0.352
1983 Andersson B, Dahmen J, Frejd T, Leffler H, Magnusson G, Noori G, Edén CS. Identification of an active disaccharide unit of a glycoconjugate receptor for pneumococci attaching to human pharyngeal epithelial cells Journal of Experimental Medicine. 158: 559-567. PMID 6886624 DOI: 10.1084/Jem.158.2.559  0.335
1982 Hansson GC, Karlsson KA, Leffler H, Strömberg N. Gangliotetraosylceramide is a major glycolipid of epithelial cells of mouse small intestine Febs Letters. 139: 291-294. PMID 7075779 DOI: 10.1016/0014-5793(82)80873-9  0.305
1982 Ångström J, Breimer ME, Falk KE, Hansson GC, Karlsson KA, Leffler H, Pascher I. Structural characterization of glycolipids of rat small intestine having one to eight hexoses in a linear sequence Archives of Biochemistry and Biophysics. 213: 708-725. PMID 7073294 DOI: 10.1016/0003-9861(82)90601-4  0.314
1982 Eden CS, Freter R, Hagberg L, Hull R, Hull S, Leffler H, Schoolnik G. Inhibition of experimental ascending urinary tract infection by an epithelial cell-surface receptor analogue Nature. 298: 560-562. PMID 7048106 DOI: 10.1038/298560A0  0.333
1981 Angstrom J, Breimer ME, Falk KE, Griph I, Hansson GC, Karlsson KA, Leffler H. Separation and characterization of hematosides with different sialic acids and ceramides from rat small intestine. Different composition of epithelial cells versus non-epithelial tissue and of duodenum versus jejunum-ileum Journal of Biochemistry. 90: 909-921. PMID 7309719 DOI: 10.1093/Oxfordjournals.Jbchem.A133579  0.311
1981 Breimer ME, Hansson GC, Karlsson KA, Leffler H. Glycosphingolipids and the differentiation of intestinal epithelium. Experimental Cell Research. 135: 1-13. PMID 7286072 DOI: 10.1016/0014-4827(81)90293-7  0.305
1981 Breimer ME, Hansson GC, Karlsson KA, Leffler H, Pimlott W, Samuelsson BE. Sequencing of oligosaccharides by mass spectrometry applied on a 12-sugar glycolipid. Febs Letters. 124: 299-303. PMID 7227534 DOI: 10.1016/0014-5793(81)80160-3  0.301
1981 Korhonen TK, Leffler H, Edén CS. Binding Specificity of Piliated Strains of Escherichia coli and Salmonella typhimurium to Epithelial Cells, Saccharomyces cerevisiae Cells, and Erythrocytes Infection and Immunity. 32: 796-804. DOI: 10.1128/Iai.32.2.796-804.1981  0.333
1980 Breimer ME, Hansson GC, Karlsson KA, Leffler H. Glycolipids of rat small intestine. Characterization of a novel blood group H-active triglycosylceramide. Biochimica Et Biophysica Acta. 617: 85-96. PMID 7353025 DOI: 10.1016/0005-2760(80)90226-X  0.311
1978 Breimer ME, Hansson GC, Karlsson KA, Leffler H, Pimlott W, Samuelsson BE. Structure determination of blood group type glycolipids of cat small intestine by mass fragmentography. Febs Letters. 89: 42-6. PMID 658400 DOI: 10.1016/0014-5793(78)80518-3  0.306
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