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Luisa Cimmino, Ph.D. - Publications

Affiliations: 
Columbia University, New York, NY 
Area:
gene regulation in the immune system
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29 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Marie IJ, Brambilla L, Azzouz D, Chen Z, Baracho GV, Arnett A, Li HS, Liu W, Cimmino L, Chattopadhyay P, Silverman G, Watowich SS, Khor B, Levy D. Tonic interferon restricts pathogenic IL-17-driven inflammatory disease via balancing the microbiome. Elife. 10. PMID 34378531 DOI: 10.7554/eLife.68371  0.346
2019 McKenzie MD, Ghisi M, Oxley EP, Ngo S, Cimmino L, Esnault C, Liu R, Salmon JM, Bell CC, Ahmed N, Erlichster M, Witkowski MT, Liu GJ, Chopin M, Dakic A, et al. Interconversion between Tumorigenic and Differentiated States in Acute Myeloid Leukemia. Cell Stem Cell. 25: 258-272.e9. PMID 31374198 DOI: 10.1016/J.Stem.2019.07.001  0.353
2018 Dominguez PM, Ghamlouch H, Rosikiewicz W, Kumar P, Béguelin W, Fontan L, Rivas MA, Pawlikowska P, Armand M, Mouly E, Torres-Martin M, Doane AS, Calvo Fernandez MT, Durant M, Della-Valle V, ... ... Cimmino L, et al. TET2 deficiency causes germinal center hyperplasia, impairs plasma cell differentiation and promotes B-cell lymphomagenesis. Cancer Discovery. PMID 30274972 DOI: 10.1158/2159-8290.Cd-18-0657  0.403
2018 Cimmino L, Neel BG, Aifantis I. Vitamin C in Stem Cell Reprogramming and Cancer. Trends in Cell Biology. PMID 29724526 DOI: 10.1016/J.Tcb.2018.04.001  0.314
2018 Teater M, Dominguez PM, Redmond D, Chen Z, Ennishi D, Scott DW, Cimmino L, Ghione P, Chaudhuri J, Gascoyne RD, Aifantis I, Inghirami G, Elemento O, Melnick A, Shaknovich R. AICDA drives epigenetic heterogeneity and accelerates germinal center-derived lymphomagenesis. Nature Communications. 9: 222. PMID 29335468 DOI: 10.1038/S41467-017-02595-W  0.403
2017 Cimmino L, Dolgalev I, Wang Y, Yoshimi A, Martin GH, Wang J, Ng V, Xia B, Witkowski MT, Mitchell-Flack M, Grillo I, Bakogianni S, Ndiaye-Lobry D, Martín MT, Guillamot M, et al. Restoration of TET2 Function Blocks Aberrant Self-Renewal and Leukemia Progression. Cell. PMID 28823558 DOI: 10.1016/J.Cell.2017.07.032  0.372
2017 Witkowski MT, Hu Y, Roberts KG, Boer JM, McKenzie MD, Liu GJ, Le Grice OD, Tremblay CS, Ghisi M, Willson TA, Horstmann MA, Aifantis I, Cimmino L, Frietze S, den Boer ML, et al. Conserved IKAROS-regulated genes associated with B-progenitor acute lymphoblastic leukemia outcome. The Journal of Experimental Medicine. PMID 28190000 DOI: 10.1084/Jem.20160048  0.416
2017 Cimmino L. Methylation maintains HSC division fate. Proceedings of the National Academy of Sciences of the United States of America. PMID 28049842 DOI: 10.1073/Pnas.1619390114  0.338
2016 Inoue S, Li WY, Tseng A, Beerman I, Elia AJ, Bendall SC, Lemonnier F, Kron KJ, Cescon DW, Hao Z, Lind EF, Takayama N, Planello AC, Shen SY, Shih AH, ... ... Cimmino L, et al. Mutant IDH1 Downregulates ATM and Alters DNA Repair and Sensitivity to DNA Damage Independent of TET2. Cancer Cell. PMID 27424808 DOI: 10.1016/J.Ccell.2016.05.018  0.304
2015 Gao J, Buckley SM, Cimmino L, Guillamot M, Strikoudis A, Cang Y, Goff SP, Aifantis I. The CUL4-DDB1 ubiquitin ligase complex controls adult and embryonic stem cell differentiation and homeostasis. Elife. 4. PMID 26613412 DOI: 10.7554/Elife.07539  0.375
2015 Mullenders J, Aranda-Orgilles B, Lhoumaud P, Keller M, Pae J, Wang K, Kayembe C, Rocha PP, Raviram R, Gong Y, Premsrirut PK, Tsirigos A, Bonneau R, Skok JA, Cimmino L, et al. Cohesin loss alters adult hematopoietic stem cell homeostasis, leading to myeloproliferative neoplasms. The Journal of Experimental Medicine. PMID 26438359 DOI: 10.1084/Jem.20151323  0.383
2015 Shih AH, Jiang Y, Meydan C, Shank K, Pandey S, Barreyro L, Antony-Debre I, Viale A, Socci N, Sun Y, Robertson A, Cavatore M, de Stanchina E, Hricik T, Rapaport F, ... ... Cimmino L, et al. Mutational cooperativity linked to combinatorial epigenetic gain of function in acute myeloid leukemia. Cancer Cell. 27: 502-15. PMID 25873173 DOI: 10.1016/J.Ccell.2015.03.009  0.345
2015 Cimmino L, Dawlaty MM, Ndiaye-Lobry D, Yap YS, Bakogianni S, Yu Y, Bhattacharyya S, Shaknovich R, Geng H, Lobry C, Mullenders J, King B, Trimarchi T, Aranda-Orgilles B, Liu C, et al. TET1 is a tumor suppressor of hematopoietic malignancy. Nature Immunology. 16: 653-62. PMID 25867473 DOI: 10.1038/Ni.3148  0.442
2015 Witkowski MT, Cimmino L, Hu Y, Trimarchi T, Tagoh H, McKenzie MD, Best SA, Tuohey L, Willson TA, Nutt SL, Busslinger M, Aifantis I, Smyth GK, Dickins RA. Activated Notch counteracts Ikaros tumor suppression in mouse and human T-cell acute lymphoblastic leukemia. Leukemia. 29: 1301-11. PMID 25655195 DOI: 10.1038/Leu.2015.27  0.524
2014 Liu GJ, Cimmino L, Jude JG, Hu Y, Witkowski MT, McKenzie MD, Kartal-Kaess M, Best SA, Tuohey L, Liao Y, Shi W, Mullighan CG, Farrar MA, Nutt SL, Smyth GK, et al. Pax5 loss imposes a reversible differentiation block in B-progenitor acute lymphoblastic leukemia. Genes & Development. 28: 1337-50. PMID 24939936 DOI: 10.1016/J.Exphem.2013.05.059  0.466
2014 Schwickert TA, Tagoh H, Gültekin S, Dakic A, Axelsson E, Minnich M, Ebert A, Werner B, Roth M, Cimmino L, Dickins RA, Zuber J, Jaritz M, Busslinger M. Stage-specific control of early B cell development by the transcription factor Ikaros. Nature Immunology. 15: 283-93. PMID 24509509 DOI: 10.1038/Ni.2828  0.447
2014 Witkowski MT, Hu Y, Cimmino L, McKenzie MD, Liu GJ, Smyth GK, Dickins RA. Reversible Tumor Suppression By Ikzf1/Ikaros in Mouse Models of BCR-ABL1+ B-ALL Blood. 124: 288-288. DOI: 10.1182/Blood.V124.21.288.288  0.424
2014 Witkowski M, Hu Y, Sathe P, McKenzie M, Cimmino L, Liu G, Keniry A, Smyth GK, Huntington N, Dickins R. Probing IKAROS functions in B-ALL using novel mouse models Experimental Hematology. 42. DOI: 10.1016/J.Exphem.2014.07.252  0.331
2013 Lobry C, Ntziachristos P, Ndiaye-Lobry D, Oh P, Cimmino L, Zhu N, Araldi E, Hu W, Freund J, Abdel-Wahab O, Ibrahim S, Skokos D, Armstrong SA, Levine RL, Park CY, et al. Notch pathway activation targets AML-initiating cell homeostasis and differentiation. The Journal of Experimental Medicine. 210: 301-19. PMID 23359070 DOI: 10.1084/Jem.20121484  0.361
2013 Shih AH, Jiang Y, Shank K, Pandey S, Viale A, Sun Y, Socci N, Robertson A, de Stanchina E, Hricik T, Rapaport F, Woods B, Cimmino L, Barreyro L, Steidl U, et al. Epigenetic Profiling Of Leukemia Stem Cells In a Model Of TET2/FLT3-Mutant AML Blood. 122: 476-476. DOI: 10.1182/Blood.V122.21.476.476  0.41
2012 Cimmino L, Aifantis I. Fingerprinting acute leukemia: DNA methylation profiling of B-acute lymphoblastic leukemia. Cancer Discovery. 2: 976-8. PMID 23148371 DOI: 10.1158/2159-8290.Cd-12-0435  0.339
2012 Kallin EM, Rodríguez-Ubreva J, Christensen J, Cimmino L, Aifantis I, Helin K, Ballestar E, Graf T. Tet2 facilitates the derepression of myeloid target genes during CEBPα-induced transdifferentiation of pre-B cells. Molecular Cell. 48: 266-76. PMID 22981865 DOI: 10.1016/J.Molcel.2012.08.007  0.441
2012 Kartal-Kaess M, Cimmino L, Infantino S, Yabas M, Zhang J, Tuohey L, Gelman IH, Scott JD, Nutt SL, Enders A, Tarlinton D, Dickins RA. RNAi Screening Identifies A Novel Role for A-Kinase Anchoring Protein 12 (AKAP12) in B Cell Development and Function Blood. 120: 855-855. DOI: 10.1182/Blood.V120.21.855.855  0.445
2012 McKenzie MD, Cimmino L, Hu Y, Rago LD, Mifsud S, Metcalf D, Smyth GK, Dickins R. Mechanisms of Tumor Suppression by the Hematopoietic Transcription Factor PU.1. Blood. 120: 2432-2432. DOI: 10.1182/Blood.V120.21.2432.2432  0.409
2011 Cimmino L, Abdel-Wahab O, Levine RL, Aifantis I. TET family proteins and their role in stem cell differentiation and transformation. Cell Stem Cell. 9: 193-204. PMID 21885017 DOI: 10.1016/J.Stem.2011.08.007  0.354
2008 Martins GA, Cimmino L, Liao J, Magnusdottir E, Calame K. Blimp-1 directly represses Il2 and the Il2 activator Fos, attenuating T cell proliferation and survival. The Journal of Experimental Medicine. 205: 1959-65. PMID 18725523 DOI: 10.1084/Jem.20080526  0.72
2008 Cimmino L, Martins GA, Liao J, Magnusdottir E, Grunig G, Perez RK, Calame KL. Blimp-1 attenuates Th1 differentiation by repression of ifng, tbx21, and bcl6 gene expression. Journal of Immunology (Baltimore, Md. : 1950). 181: 2338-47. PMID 18684923 DOI: 10.4049/Jimmunol.181.4.2338  0.721
2007 Savitsky D, Cimmino L, Kuo T, Martins GA, Calame K. Multiple roles for Blimp-1 in B and T lymphocytes. Advances in Experimental Medicine and Biology. 596: 9-30. PMID 17338172 DOI: 10.1007/0-387-46530-8_2  0.638
2006 Martins GA, Cimmino L, Shapiro-Shelef M, Szabolcs M, Herron A, Magnusdottir E, Calame K. Transcriptional repressor Blimp-1 regulates T cell homeostasis and function. Nature Immunology. 7: 457-65. PMID 16565721 DOI: 10.1038/Ni1320  0.743
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