| Year |
Citation |
Score |
| 2020 |
Sarkar D, Olejniczak ET, Phan J, Coker JA, Sai J, Arnold AL, Beesetty Y, Waterson AG, Fesik SW. Discovery of Sulfonamide-Derived Agonists of SOS1-Mediated Nucleotide Exchange on RAS Using Fragment-Based Methods. Journal of Medicinal Chemistry. PMID 32673492 DOI: 10.1021/Acs.Jmedchem.0C00511 |
0.32 |
|
| 2019 |
Tian J, Teuscher K, Aho ER, Alvarado JR, Mills JJ, Meyers KM, Gogliotti RD, Han C, Macdonald JD, Sai J, Shaw JG, Sensintaffar JL, Zhao B, Rietz TA, Thomas LR, et al. Discovery and Structure-Based Optimization of Potent and Selective WD repeat domain 5 (WDR5) Inhibitors Containing a Dihydroisoquinolinone Bicyclic Core. Journal of Medicinal Chemistry. PMID 31858797 DOI: 10.1021/Acs.Jmedchem.9B01608 |
0.343 |
|
| 2019 |
Macdonald JD, Chacon Simon S, Han C, Wang F, Shaw JG, Howes JE, Sai J, Yuh J, Camper DV, Alicie BM, Alvarado J, Nikhar S, Payne WG, Aho ER, Bauer J, et al. Discovery and Optimization of Salicylic Acid-Derived Sulfonamide Inhibitors of the WD Repeat-Containing Protein 5 (WDR5)-MYC Protein-Protein Interaction. Journal of Medicinal Chemistry. PMID 31724864 DOI: 10.1021/Acs.Jmedchem.9B01411 |
0.325 |
|
| 2019 |
Kessler D, Gmachl M, Mantoulidis A, Martin LJ, Zoephel A, Mayer M, Gollner A, Covini D, Fischer S, Gerstberger T, Gmaschitz T, Goodwin C, Greb P, Häring D, Hela W, ... ... Sai J, et al. Drugging an undruggable pocket on KRAS. Proceedings of the National Academy of Sciences of the United States of America. PMID 31332011 DOI: 10.1073/Pnas.1904529116 |
0.333 |
|
| 2019 |
Akan DT, Howes JE, Sai J, Arnold AL, Beesetty Y, Phan J, Olejniczak ET, Waterson AG, Fesik SW. Small molecule SOS1 agonists modulate MAPK and PI3K signaling via independent cellular responses. Acs Chemical Biology. PMID 30735352 DOI: 10.1021/Acschembio.8B00869 |
0.331 |
|
| 2016 |
Saxon JA, Sherrill TP, Polosukhin VV, Sai J, Zaynagetdinov R, McLoed AG, Gulleman PM, Barham W, Cheng DS, Hunt RP, Gleaves LA, Richmond A, Young LR, Yull FE, Blackwell TS. Epithelial NF-κB signaling promotes EGFR-driven lung carcinogenesis via macrophage recruitment. Oncoimmunology. 5: e1168549. PMID 27471643 DOI: 10.1080/2162402X.2016.1168549 |
0.319 |
|
| 2016 |
Sai J, Rogers M, Hockemeyer K, Wikswo JP, Richmond A. Study of Chemotaxis and Cell-Cell Interactions in Cancer with Microfluidic Devices. Methods in Enzymology. 570: 19-45. PMID 26921940 DOI: 10.1016/Bs.Mie.2015.09.023 |
0.338 |
|
| 2016 |
Lavender N, Yang J, Sai J, Novitskiy S, Horton L, Johnson A, Abramson V, Mayer I, Meszoely I, Kelley M, Richmond A. Abstract 1410: PI3K inhibitors reduce breast cancer tumor growth and enhance anti-tumor leukocyte activity Cancer Research. 76: 1410-1410. DOI: 10.1158/1538-7445.Am2016-1410 |
0.302 |
|
| 2015 |
Lavender N, Sai J, Yang J, Novitskiy SV, Richmond A. Abstract 422: The role of CCL2 in the breast cancer tumor microenvironment and metastasis Cancer Research. 75: 422-422. DOI: 10.1158/1538-7445.Am2015-422 |
0.311 |
|
| 2014 |
Raman D, Sai J, Hawkins O, Richmond A. Adaptor protein2 (AP2) orchestrates CXCR2-mediated cell migration Traffic. 15: 451-469. PMID 24450359 DOI: 10.1111/Tra.12154 |
0.34 |
|
| 2011 |
Neel NF, Sai J, Ham AJ, Sobolik-Delmaire T, Mernaugh RL, Richmond A. IQGAP1 is a novel CXCR2-interacting protein and essential component of the "chemosynapse". Plos One. 6: e23813. PMID 21876773 DOI: 10.1371/Journal.Pone.0023813 |
0.403 |
|
| 2010 |
Das ST, Rajagopalan L, Guerrero-Plata A, Sai J, Richmond A, Garofalo RP, Rajarathnam K. Monomeric and dimeric CXCL8 are both essential for in vivo neutrophil recruitment. Plos One. 5: e11754. PMID 20668677 DOI: 10.1371/Journal.Pone.0011754 |
0.348 |
|
| 2010 |
Raman D, Sai J, Neel NF, Chew CS, Richmond A. LIM and SH3 protein-1 modulates CXCR2-mediated cell migration. Plos One. 5: e10050. PMID 20419088 DOI: 10.1371/Journal.Pone.0010050 |
0.375 |
|
| 2009 |
Raman D, Neel NF, Sai J, Mernaugh RL, Ham AJ, Richmond AJ. Characterization of chemokine receptor CXCR2 interacting proteins using a proteomics approach to define the CXCR2 "chemosynapse". Methods in Enzymology. 460: 315-30. PMID 19446732 DOI: 10.1016/S0076-6879(09)05215-X |
0.355 |
|
| 2009 |
Neel NF, Barzik M, Raman D, Sobolik-Delmaire T, Sai J, Ham AJ, Mernaugh RL, Gertler FB, Richmond A. VASP is a CXCR2-interacting protein that regulates CXCR2-mediated polarization and chemotaxis. Journal of Cell Science. 122: 1882-94. PMID 19435808 DOI: 10.1242/Jcs.039057 |
0.386 |
|
| 2008 |
Sai J, Raman D, Liu Y, Wikswo J, Richmond A. Parallel phosphatidylinositol 3-kinase (PI3K)-dependent and Src-dependent pathways lead to CXCL8-mediated Rac2 activation and chemotaxis. The Journal of Biological Chemistry. 283: 26538-47. PMID 18662984 DOI: 10.1074/Jbc.M805611200 |
0.36 |
|
| 2008 |
Liu Y, Sai J, Richmond A, Wikswo JP. Microfluidic switching system for analyzing chemotaxis responses of wortmannin-inhibited HL-60 cells. Biomedical Microdevices. 10: 499-507. PMID 18205049 DOI: 10.1007/S10544-007-9158-Z |
0.332 |
|
| 2007 |
Miller-Kittrell M, Sai J, Penfold M, Richmond A, Sparer TE. Functional characterization of chimpanzee cytomegalovirus chemokine, vCXCL-1(CCMV). Virology. 364: 454-65. PMID 17433398 DOI: 10.1016/J.Virol.2007.03.002 |
0.331 |
|
| 2006 |
Sai J, Walker G, Wikswo J, Richmond A. The IL sequence in the LLKIL motif in CXCR2 is required for full ligand-induced activation of Erk, Akt, and chemotaxis in HL60 cells. The Journal of Biological Chemistry. 281: 35931-41. PMID 16990258 DOI: 10.1074/Jbc.M605883200 |
0.376 |
|
| 2005 |
Neel NF, Schutyser E, Sai J, Fan GH, Richmond A. Chemokine receptor internalization and intracellular trafficking. Cytokine & Growth Factor Reviews. 16: 637-58. PMID 15998596 DOI: 10.1016/J.Cytogfr.2005.05.008 |
0.316 |
|
| 2004 |
Sai J, Fan GH, Wang D, Richmond A. The C-terminal domain LLKIL motif of CXCR2 is required for ligand-mediated polarization of early signals during chemotaxis. Journal of Cell Science. 117: 5489-96. PMID 15479720 DOI: 10.1242/Jcs.01398 |
0.387 |
|
| 2004 |
Fan GH, Lapierre LA, Goldenring JR, Sai J, Richmond A. Rab11-family interacting protein 2 and myosin Vb are required for CXCR2 recycling and receptor-mediated chemotaxis. Molecular Biology of the Cell. 15: 2456-69. PMID 15004234 DOI: 10.1091/Mbc.E03-09-0706 |
0.379 |
|
| 2003 |
Wang D, Sai J, Richmond A. Cell surface heparan sulfate participates in CXCL1-induced signaling. Biochemistry. 42: 1071-7. PMID 12549928 DOI: 10.1021/Bi026425A |
0.383 |
|
| 2002 |
Sai J, Johnson CH. Dark-stimulated calcium ion fluxes in the chloroplast stroma and cytosol. The Plant Cell. 14: 1279-91. PMID 12084827 DOI: 10.1105/Tpc.000653 |
0.416 |
|
| 2002 |
Fan GH, Yang W, Sai J, Richmond A. Hsc/Hsp70 interacting protein (hip) associates with CXCR2 and regulates the receptor signaling and trafficking. The Journal of Biological Chemistry. 277: 6590-7. PMID 11751889 DOI: 10.1074/Jbc.M110588200 |
0.386 |
|
| 2001 |
Fan GH, Yang W, Sai J, Richmond A. Phosphorylation-independent association of CXCR2 with the protein phosphatase 2A core enzyme. The Journal of Biological Chemistry. 276: 16960-8. PMID 11278485 DOI: 10.1074/Jbc.M009292200 |
0.367 |
|
| 1999 |
Sai J, Johnson CH. Different circadian oscillators control Ca(2+) fluxes and lhcb gene expression. Proceedings of the National Academy of Sciences of the United States of America. 96: 11659-63. PMID 10500233 DOI: 10.1073/Pnas.96.20.11659 |
0.43 |
|
| Show low-probability matches. |