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Timothy C. Meredith, Ph.D. - Publications

Affiliations: 
2006 University of Michigan, Ann Arbor, Ann Arbor, MI 
Area:
Enzyme Mechanism of Carbohydrate Biosynthetic Pathways
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40 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Gardiner JH, Komazin G, Matsuo M, Cole K, Götz F, Meredith TC. Lipoprotein -Acylation in Is Catalyzed by a Two-Component Acyl Transferase System. Mbio. 11. PMID 32723923 DOI: 10.1128/Mbio.01619-20  0.441
2020 Armbruster KM, Komazin G, Meredith TC. Bacterial lyso-form lipoproteins are synthesized via an intramolecular acyl chain migration. The Journal of Biological Chemistry. PMID 32471867 DOI: 10.1074/Jbc.Ra120.014000  0.427
2019 Coe KA, Lee W, Stone MC, Komazin-Meredith G, Meredith TC, Grad YH, Walker S. Multi-strain Tn-Seq reveals common daptomycin resistance determinants in Staphylococcus aureus. Plos Pathogens. 15: e1007862. PMID 31738809 DOI: 10.1371/Journal.Ppat.1007862  0.378
2019 Komazin G, Maybin M, Woodard RW, Scior T, Schwudke D, Schombel U, Gisch N, Mamat U, Meredith TC. Substrate structure-activity relationship reveals a limited lipopolysaccharide chemotype range for intestinal alkaline phosphatase. The Journal of Biological Chemistry. PMID 31704704 DOI: 10.1074/Jbc.Ra119.010836  0.642
2019 Armbruster KM, Komazin G, Meredith TC. Copper-induced expression of a transmissible lipoprotein intramolecular transacylase alters lipoprotein acylation and the Toll-like receptor 2 response to . Journal of Bacteriology. PMID 30988036 DOI: 10.1128/Jb.00195-19  0.445
2018 Armbruster KM, Meredith TC. Enrichment of Bacterial Lipoproteins and Preparation of N-terminal Lipopeptides for Structural Determination by Mass Spectrometry. Journal of Visualized Experiments : Jove. PMID 29863685 DOI: 10.3791/56842  0.322
2018 Zhang G, Baidin V, Pahil KS, Moison E, Tomasek D, Ramadoss NS, Chatterjee AK, McNamara CW, Young TS, Schultz PG, Meredith TC, Kahne D. Cell-based screen for discovering lipopolysaccharide biogenesis inhibitors. Proceedings of the National Academy of Sciences of the United States of America. PMID 29735709 DOI: 10.1073/Pnas.1804670115  0.441
2018 Santiago M, Lee W, Fayad AA, Coe KA, Rajagopal M, Do T, Hennessen F, Srisuknimit V, Müller R, Meredith TC, Walker S. Genome-wide mutant profiling predicts the mechanism of a Lipid II binding antibiotic. Nature Chemical Biology. PMID 29662210 DOI: 10.1038/S41589-018-0041-4  0.377
2018 Kho K, Meredith TC. Salt-Induced Stress Stimulates a Lipoteichoic Acid-Specific Three Component Glycosylation System in . Journal of Bacteriology. PMID 29632092 DOI: 10.1128/Jb.00017-18  0.394
2018 Lee W, Do T, Zhang G, Kahne D, Meredith TC, Walker S. Antibiotic combinations that enable one-step, targeted mutagenesis of chromosomal genes. Acs Infectious Diseases. PMID 29534563 DOI: 10.1021/Acsinfecdis.8B00017  0.362
2017 Matano LM, Morris HG, Hesser AR, Martin SES, Lee W, Owens TW, Laney E, Nakaminami H, Hooper D, Meredith TC, Walker S. An antibiotic that inhibits the ATPase activity of an ABC transporter by binding to a remote extracellular site. Journal of the American Chemical Society. PMID 28727445 DOI: 10.1021/Jacs.7B04726  0.332
2017 Armbruster KM, Meredith TC. Identification of the Lyso-Form N-acyl Intramolecular Transferase in Low-GC Firmicutes. Journal of Bacteriology. PMID 28320885 DOI: 10.1128/Jb.00099-17  0.425
2017 Moison E, Xie R, Zhang G, Lebar MD, Meredith TC, Kahne D. A fluorescent probe distinguishes between inhibition of early and late steps of lipopolysaccharide biogenesis in whole cells. Acs Chemical Biology. PMID 28248483 DOI: 10.1021/Acschembio.7B00159  0.416
2016 Rajagopal M, Martin MJ, Santiago M, Lee W, Kos VN, Meredith T, Gilmore MS, Walker S. Multidrug Intrinsic Resistance Factors in Staphylococcus aureus Identified by Profiling Fitness within High-Diversity Transposon Libraries. Mbio. 7. PMID 27531908 DOI: 10.1128/Mbio.00950-16  0.369
2015 Pasquina L, Santa Maria JP, McKay Wood B, Moussa SH, Matano LM, Santiago M, Martin SE, Lee W, Meredith TC, Walker S. A synthetic lethal approach for compound and target identification in Staphylococcus aureus. Nature Chemical Biology. PMID 26619249 DOI: 10.1038/Nchembio.1967  0.363
2015 Mamat U, Wilke K, Bramhill D, Schromm AB, Lindner B, Kohl TA, Corchero JL, Villaverde A, Schaffer L, Head SR, Souvignier C, Meredith TC, Woodard RW. Erratum to: Detoxifying Escherichia coli for endotoxin-free production of recombinant proteins. Microbial Cell Factories. 14: 81. PMID 26063122 DOI: 10.1186/S12934-015-0265-X  0.545
2015 Mamat U, Wilke K, Bramhill D, Schromm AB, Lindner B, Kohl TA, Corchero JL, Villaverde A, Schaffer L, Head SR, Souvignier C, Meredith TC, Woodard RW. Detoxifying Escherichia coli for endotoxin-free production of recombinant proteins. Microbial Cell Factories. 14: 57. PMID 25890161 DOI: 10.1186/S12934-015-0241-5  0.663
2015 Santiago M, Matano LM, Moussa SH, Gilmore MS, Walker S, Meredith TC. A new platform for ultra-high density Staphylococcus aureus transposon libraries. Bmc Genomics. 16: 252. PMID 25888466 DOI: 10.1186/S12864-015-1361-3  0.358
2014 Six DA, Yuan Y, Leeds JA, Meredith TC. Deletion of the β-acetoacetyl synthase FabY in Pseudomonas aeruginosa induces hypoacylation of lipopolysaccharide and increases antimicrobial susceptibility. Antimicrobial Agents and Chemotherapy. 58: 153-61. PMID 24145528 DOI: 10.1128/Aac.01804-13  0.42
2013 Makitrynskyy R, Ostash B, Tsypik O, Rebets Y, Doud E, Meredith T, Luzhetskyy A, Bechthold A, Walker S, Fedorenko V. Pleiotropic regulatory genes bldA, adpA and absB are implicated in production of phosphoglycolipid antibiotic moenomycin. Open Biology. 3: 130121. PMID 24153004 DOI: 10.1098/Rsob.130121  0.305
2013 Zhang G, Meredith TC, Kahne D. On the essentiality of lipopolysaccharide to Gram-negative bacteria. Current Opinion in Microbiology. 16: 779-85. PMID 24148302 DOI: 10.1016/J.Mib.2013.09.007  0.429
2013 Wang H, Gill CJ, Lee SH, Mann P, Zuck P, Meredith TC, Murgolo N, She X, Kales S, Liang L, Liu J, Wu J, Santa Maria J, Su J, Pan J, et al. Discovery of wall teichoic acid inhibitors as potential anti-MRSA β-lactam combination agents. Chemistry & Biology. 20: 272-84. PMID 23438756 DOI: 10.1016/J.Chembiol.2012.11.013  0.32
2012 Meredith TC, Wang H, Beaulieu P, Gründling A, Roemer T. Harnessing the power of transposon mutagenesis for antibacterial target identification and evaluation. Mobile Genetic Elements. 2: 171-178. PMID 23094235 DOI: 10.4161/Mge.21647  0.365
2012 Brown S, Xia G, Luhachack LG, Campbell J, Meredith TC, Chen C, Winstel V, Gekeler C, Irazoqui JE, Peschel A, Walker S. Methicillin resistance in Staphylococcus aureus requires glycosylated wall teichoic acids. Proceedings of the National Academy of Sciences of the United States of America. 109: 18909-14. PMID 23027967 DOI: 10.1073/Pnas.1209126109  0.329
2012 Yuan Y, Sachdeva M, Leeds JA, Meredith TC. Fatty acid biosynthesis in Pseudomonas aeruginosa is initiated by the FabY class of β-ketoacyl acyl carrier protein synthases. Journal of Bacteriology. 194: 5171-84. PMID 22753059 DOI: 10.1128/Jb.00792-12  0.381
2012 Yuan Y, Leeds JA, Meredith TC. Pseudomonas aeruginosa directly shunts β-oxidation degradation intermediates into de novo fatty acid biosynthesis. Journal of Bacteriology. 194: 5185-96. PMID 22753057 DOI: 10.1128/Jb.00860-12  0.328
2012 Tan CM, Therien AG, Lu J, Lee SH, Caron A, Gill CJ, Lebeau-Jacob C, Benton-Perdomo L, Monteiro JM, Pereira PM, Elsen NL, Wu J, Deschamps K, Petcu M, Wong S, ... ... Meredith TC, et al. Restoring methicillin-resistant Staphylococcus aureus susceptibility to β-lactam antibiotics. Science Translational Medicine. 4: 126ra35. PMID 22440737 DOI: 10.1126/Scitranslmed.3003592  0.312
2011 Wang H, Claveau D, Vaillancourt JP, Roemer T, Meredith TC. High-frequency transposition for determining antibacterial mode of action. Nature Chemical Biology. 7: 720-9. PMID 21892185 DOI: 10.1038/Nchembio.643  0.338
2011 Mosberg JA, Yep A, Meredith TC, Smith S, Wang PF, Holler TP, Mobley HL, Woodard RW. A unique arabinose 5-phosphate isomerase found within a genomic island associated with the uropathogenicity of Escherichia coli CFT073. Journal of Bacteriology. 193: 2981-8. PMID 21498648 DOI: 10.1128/Jb.00033-11  0.597
2010 Brown S, Meredith T, Swoboda J, Walker S. Staphylococcus aureus and Bacillus subtilis W23 make polyribitol wall teichoic acids using different enzymatic pathways. Chemistry & Biology. 17: 1101-10. PMID 21035733 DOI: 10.1016/J.Chembiol.2010.07.017  0.363
2010 Swoboda JG, Campbell J, Meredith TC, Walker S. Wall teichoic acid function, biosynthesis, and inhibition. Chembiochem : a European Journal of Chemical Biology. 11: 35-45. PMID 19899094 DOI: 10.1002/Cbic.200900557  0.384
2009 Swoboda JG, Meredith TC, Campbell J, Brown S, Suzuki T, Bollenbach T, Malhowski AJ, Kishony R, Gilmore MS, Walker S. Discovery of a small molecule that blocks wall teichoic acid biosynthesis in Staphylococcus aureus. Acs Chemical Biology. 4: 875-83. PMID 19689117 DOI: 10.1021/Cb900151K  0.411
2009 Mamat U, Schmidt H, Munoz E, Lindner B, Fukase K, Hanuszkiewicz A, Wu J, Meredith TC, Woodard RW, Hilgenfeld R, Mesters JR, Holst O. WaaA of the hyperthermophilic bacterium Aquifex aeolicus is a monofunctional 3-deoxy-D-manno-oct-2-ulosonic acid transferase involved in lipopolysaccharide biosynthesis. The Journal of Biological Chemistry. 284: 22248-62. PMID 19546212 DOI: 10.1074/Jbc.M109.033308  0.677
2008 Meredith TC, Swoboda JG, Walker S. Late-stage polyribitol phosphate wall teichoic acid biosynthesis in Staphylococcus aureus. Journal of Bacteriology. 190: 3046-56. PMID 18281399 DOI: 10.1128/Jb.01880-07  0.382
2008 Mamat U, Meredith TC, Aggarwal P, Kühl A, Kirchhoff P, Lindner B, Hanuszkiewicz A, Sun J, Holst O, Woodard RW. Single amino acid substitutions in either YhjD or MsbA confer viability to 3-deoxy-d-manno-oct-2-ulosonic acid-depleted Escherichia coli. Molecular Microbiology. 67: 633-48. PMID 18093093 DOI: 10.1111/J.1365-2958.2007.06074.X  0.7
2007 Meredith TC, Mamat U, Kaczynski Z, Lindner B, Holst O, Woodard RW. Modification of lipopolysaccharide with colanic acid (M-antigen) repeats in Escherichia coli. The Journal of Biological Chemistry. 282: 7790-8. PMID 17227761 DOI: 10.1074/Jbc.M611034200  0.613
2006 Meredith TC, Aggarwal P, Mamat U, Lindner B, Woodard RW. Redefining the requisite lipopolysaccharide structure in Escherichia coli. Acs Chemical Biology. 1: 33-42. PMID 17163638 DOI: 10.1021/Cb0500015  0.712
2006 Meredith TC, Woodard RW. Characterization of Escherichia coli D-arabinose 5-phosphate isomerase encoded by kpsF: implications for group 2 capsule biosynthesis. The Biochemical Journal. 395: 427-32. PMID 16390329 DOI: 10.1042/Bj20051828  0.629
2005 Meredith TC, Woodard RW. Identification of GutQ from Escherichia coli as a D-arabinose 5-phosphate isomerase. Journal of Bacteriology. 187: 6936-42. PMID 16199563 DOI: 10.1128/Jb.187.20.6936-6942.2005  0.66
2003 Meredith TC, Woodard RW. Escherichia coli YrbH is a D-arabinose 5-phosphate isomerase. The Journal of Biological Chemistry. 278: 32771-7. PMID 12805358 DOI: 10.1074/Jbc.M303661200  0.621
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