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Sarah M. McLeod, Ph.D. - Publications

Affiliations: 
2001 University of California, Los Angeles, Los Angeles, CA 
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22 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Durand-Reville TF, Comita-Prevoir J, Zhang J, Wu X, May-Dracka T, Romero J, Wu F, Chen A, Shapiro AB, Carter N, McLeod S, Giacobbe R, Verheijen J, Lahiri S, Sacco M, et al. Discovery of an Orally Available Diazabicyclooctane Inhibitor (ETX0282) of Class A, C and D Serine β-lactamases. Journal of Medicinal Chemistry. PMID 32658473 DOI: 10.1021/Acs.Jmedchem.0C00579  0.336
2020 Miller AA, Shapiro AB, McLeod S, Carter NM, Moussa SH, Tommasi R, Mueller JP. In vitro Characterization of ETX1317, a broad-spectrum β-lactamase inhibitor that restores and enhances β-lactam activity against multidrug resistant Enterobacteriales, including carbapenem-resistant strains. Acs Infectious Diseases. PMID 32255609 DOI: 10.1021/Acsinfecdis.0C00020  0.356
2020 McLeod SM, Moussa SH, Hackel MA, Miller AA. activity of sulbactam-durlobactam against complex isolates collected globally from 2016-2017. Antimicrobial Agents and Chemotherapy. PMID 31988095 DOI: 10.1128/Aac.02534-19  0.38
2019 Miller A, McLeod S, Mathur T, Morrissey I. 694. In vitro Antibacterial Activity of Sulbactam–Durlobactam (ETX2514SUL) Against 121 Recent Acinetobacter baumannii Isolated from Patients in India Open Forum Infectious Diseases. 6: S314-S314. DOI: 10.1093/Ofid/Ofz360.762  0.356
2017 McLeod SM, Shapiro AB, Moussa SH, Johnstone M, McLaughlin RE, de Jonge BLM, Miller AA. The frequency and mechanism of spontaneous resistance to sulbactam combined with the novel β-lactamase inhibitor ETX2514 in clinical isolates of Acinetobacter baumannii. Antimicrobial Agents and Chemotherapy. PMID 29133555 DOI: 10.1128/Aac.01576-17  0.367
2017 Durand-Réville TF, Guler S, Comita-Prevoir J, Chen B, Bifulco N, Huynh H, Lahiri S, Shapiro AB, McLeod SM, Carter NM, Moussa SH, Velez-Vega C, Olivier NB, McLaughlin R, Gao N, et al. ETX2514 is a broad-spectrum β-lactamase inhibitor for the treatment of drug-resistant Gram-negative bacteria including Acinetobacter baumannii. Nature Microbiology. 2: 17104. PMID 28665414 DOI: 10.1038/Nmicrobiol.2017.104  0.375
2017 McLeod SM, Patey SA, Huband MD, Nichols WW. Impact of defined cell envelope mutations in Escherichia coli on the in vitro antibacterial activity of avibactam/β-lactam combinations. International Journal of Antimicrobial Agents. PMID 28242258 DOI: 10.1016/J.Ijantimicag.2016.12.011  0.395
2016 McLeod S, Shapiro A, Moussa S, Carter N, Johnstone M, McLaughlin R, Dejonge B, Tommasi R, Mueller J, Miller A. Sulbactam Combined With the Novel β-lactamase Inhibitor ETX2514 for the Treatment of Multidrug-Resistant Acinetobacter baumannii Infections Open Forum Infectious Diseases. 3. DOI: 10.1093/Ofid/Ofw172.1794  0.314
2015 Nayar AS, Dougherty TJ, Ferguson KE, Granger BA, McWilliams L, Stacey C, Leach LJ, Narita S, Tokuda H, Miller AA, Brown DG, McLeod SM. Novel antibacterial targets and compounds revealed by a high-throughput cell wall reporter assay. Journal of Bacteriology. 197: 1726-34. PMID 25733621 DOI: 10.1128/Jb.02552-14  0.338
2015 McLeod SM, Fleming PR, MacCormack K, McLaughlin RE, Whiteaker JD, Narita S, Mori M, Tokuda H, Miller AA. Small-molecule inhibitors of gram-negative lipoprotein trafficking discovered by phenotypic screening. Journal of Bacteriology. 197: 1075-82. PMID 25583975 DOI: 10.1128/Jb.02352-14  0.318
2014 Gao N, McLeod SM, Hajec L, Olivier NB, Lahiri SD, Bryan Prince D, Thresher J, Ross PL, Whiteaker JD, Doig P, Li AH, Hill PJ, Cornebise M, Reck F, Hale MR. Overexpression of Pseudomonas aeruginosa LpxC with its inhibitors in an acrB-deficient Escherichia coli strain. Protein Expression and Purification. 104: 57-64. PMID 25240855 DOI: 10.1016/J.Pep.2014.09.006  0.338
2014 Abibi A, Ferguson AD, Fleming PR, Gao N, Hajec LI, Hu J, Laganas VA, McKinney DC, McLeod SM, Prince DB, Shapiro AB, Buurman ET. The role of a novel auxiliary pocket in bacterial phenylalanyl-tRNA synthetase druggability. The Journal of Biological Chemistry. 289: 21651-62. PMID 24936059 DOI: 10.1074/Jbc.M114.574061  0.406
2014 Ma J, McLeod S, MacCormack K, Sriram S, Gao N, Breeze AL, Hu J. Real-time monitoring of New Delhi metallo-β-lactamase activity in living bacterial cells by 1H NMR spectroscopy. Angewandte Chemie (International Ed. in English). 53: 2130-3. PMID 24458501 DOI: 10.1002/Anie.201308636  0.354
2014 Gao N, McLeod SM, Hajec H, Lahiri SD, Prince DB, Thresher J, Whiteaker J, Ross P, Olivier NB, Doig P. Overexpression of Pseudomonas aeruginosa LpxC in the Presence of an Inhibitor in an acrB Deletion Escherichia coli strain for Structural Studies Protein Expression and Purification. DOI: 10.2210/Pdb4Okg/Pdb  0.301
2007 Yamaichi Y, Fogel MA, McLeod SM, Hui MP, Waldor MK. Distinct centromere-like parS sites on the two chromosomes of Vibrio spp. Journal of Bacteriology. 189: 5314-24. PMID 17496089 DOI: 10.1128/Jb.00416-07  0.329
2006 Skoko D, Yoo D, Bai H, Schnurr B, Yan J, McLeod SM, Marko JF, Johnson RC. Mechanism of chromosome compaction and looping by the Escherichia coli nucleoid protein Fis. Journal of Molecular Biology. 364: 777-98. PMID 17045294 DOI: 10.1016/J.Jmb.2006.09.043  0.464
2004 McLeod SM, Waldor MK. Characterization of XerC- and XerD-dependent CTX phage integration in Vibrio cholerae. Molecular Microbiology. 54: 935-47. PMID 15522078 DOI: 10.1111/J.1365-2958.2004.04309.X  0.337
2002 McLeod SM, Aiyar SE, Gourse RL, Johnson RC. The C-terminal domains of the RNA polymerase alpha subunits: contact site with Fis and localization during co-activation with CRP at the Escherichia coli proP P2 promoter. Journal of Molecular Biology. 316: 517-29. PMID 11866515 DOI: 10.1006/Jmbi.2001.5391  0.537
2002 Aiyar SE, McLeod SM, Ross W, Hirvonen CA, Thomas MS, Johnson RC, Gourse RL. Architecture of Fis-activated transcription complexes at the Escherichia coli rrnB P1 and rrnE P1 promoters. Journal of Molecular Biology. 316: 501-16. PMID 11866514 DOI: 10.1006/Jmbi.2001.5390  0.532
2001 McLeod SM, Johnson RC. Control of transcription by nucleoid proteins. Current Opinion in Microbiology. 4: 152-9. PMID 11282470 DOI: 10.1016/S1369-5274(00)00181-8  0.478
2000 McLeod SM, Xu J, Johnson RC. Coactivation of the RpoS-dependent proP P2 promoter by fis and cyclic AMP receptor protein. Journal of Bacteriology. 182: 4180-7. PMID 10894725 DOI: 10.1128/Jb.182.15.4180-4187.2000  0.547
1999 McLeod SM, Xu J, Cramton SE, Gaal T, Gourse RL, Johnson RC. Localization of amino acids required for Fis to function as a class II transcriptional activator at the RpoS-dependent proP P2 promoter. Journal of Molecular Biology. 294: 333-46. PMID 10610762 DOI: 10.1006/Jmbi.1999.3262  0.54
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