| Year |
Citation |
Score |
| 2024 |
Serafim MSM, Kronenberger T, Rocha REO, Rosa ADRA, Mello TLG, Poso A, Ferreira RS, Abrahão JS, Kroon EG, Mota BEF, Maltarollo VG. Aminopyrimidine Derivatives as Multiflavivirus Antiviral Compounds Identified from a Consensus Virtual Screening Approach. Journal of Chemical Information and Modeling. PMID 38194508 DOI: 10.1021/acs.jcim.3c01505 |
0.308 |
|
| 2023 |
Santos LH, Rocha REO, Dias DL, Ribeiro BMRM, Serafim MSM, Abrahão JS, Ferreira RS. Evaluating Known Zika Virus NS2B-NS3 Protease Inhibitor Scaffolds via In Silico Screening and Biochemical Assays. Pharmaceuticals (Basel, Switzerland). 16. PMID 37765127 DOI: 10.3390/ph16091319 |
0.44 |
|
| 2023 |
Reis RCFM, Dos Santos EG, Benedetti MD, Reis ACC, Brandão GC, Silva GND, Diniz LA, Ferreira RS, Caldas IS, Braga SFP, Souza TB. Design and synthesis of new 1,2,3-triazoles derived from eugenol and analogues with in vitro and in vivo activity against Trypanosoma cruzi. European Journal of Medicinal Chemistry. 258: 115622. PMID 37441850 DOI: 10.1016/j.ejmech.2023.115622 |
0.309 |
|
| 2023 |
Maltarollo VG, da Silva EB, Kronenberger T, Sena Andrade MM, de Lima Marques GV, Cândido Oliveira NJ, Santos LH, Oliveira Rezende Júnior C, Cassiano Martinho AC, Skinner D, Fajtová P, M Fernandes TH, Silveira Dos Santos ED, Rodrigues Gazolla PA, Martins de Souza AP, ... ... Ferreira RS, et al. Structure-based discovery of thiosemicarbazones as SARS-CoV-2 main protease inhibitors. Future Medicinal Chemistry. PMID 37435731 DOI: 10.4155/fmc-2023-0034 |
0.307 |
|
| 2023 |
Santos VC, Leite PG, Santos LH, Pascutti PG, Kolb P, Machado FS, Ferreira RS. Structure-based discovery of novel cruzain inhibitors with distinct trypanocidal activity profiles. European Journal of Medicinal Chemistry. 257: 115498. PMID 37290182 DOI: 10.1016/j.ejmech.2023.115498 |
0.682 |
|
| 2023 |
Gazolla PAR, de Aguiar AR, Costa MCA, Oliveira OV, Costa AV, da Silva CM, do Nascimento CJ, Junker J, Ferreira RS, de Oliveira FM, Vaz BG, do Carmo PHF, Santos DA, Ferreira MMC, Teixeira RR. Synthesis of vanillin derivatives with 1,2,3-triazole fragments and evaluation of their fungicide and fungistatic activities. Archiv Der Pharmazie. e202200653. PMID 36922908 DOI: 10.1002/ardp.202200653 |
0.31 |
|
| 2023 |
do Valle Moreira T, Martins LC, Diniz LA, Bernardes TCD, de Oliveira RB, Ferreira RS. Screening the Pathogen Box to Discover and Characterize New Cruzain and CatL Inhibitors. Pathogens (Basel, Switzerland). 12. PMID 36839523 DOI: 10.3390/pathogens12020251 |
0.306 |
|
| 2023 |
Martins LC, de Oliveira RB, Lameira J, Ferreira RS. Experimental and Computational Study of Aryl-thiosemicarbazones Inhibiting Cruzain Reveals Reversible Inhibition and a Stepwise Mechanism. Journal of Chemical Information and Modeling. PMID 36802548 DOI: 10.1021/acs.jcim.2c01566 |
0.329 |
|
| 2022 |
Braga SFP, Santos VC, Vieira RP, Silva EBD, Monti L, Krake SH, Martinez PDG, Dias LC, Caffrey CR, Siqueira-Neto JL, de Oliveira RB, Ferreira RS. From rational design to serendipity: Discovery of novel thiosemicarbazones as potent trypanocidal compounds. European Journal of Medicinal Chemistry. 244: 114876. PMID 36343429 DOI: 10.1016/j.ejmech.2022.114876 |
0.307 |
|
| 2022 |
Qayed WS, Ferreira RS, Silva JRA. In Silico Study towards Repositioning of FDA-Approved Drug Candidates for Anticoronaviral Therapy: Molecular Docking, Molecular Dynamics and Binding Free Energy Calculations. Molecules (Basel, Switzerland). 27. PMID 36144718 DOI: 10.3390/molecules27185988 |
0.306 |
|
| 2022 |
Fassio AV, Shub L, Ponzoni L, McKinley J, O'Meara MJ, Ferreira RS, Keiser MJ, de Melo Minardi RC. Prioritizing Virtual Screening with Interpretable Interaction Fingerprints. Journal of Chemical Information and Modeling. 62: 4300-4318. PMID 36102784 DOI: 10.1021/acs.jcim.2c00695 |
0.705 |
|
| 2022 |
Martinho ACC, Resende DM, Landin ES, Dit Lapierre TJWJ, Bernardes TCD, Martins LC, Ferreira RS, Murta SMF, de Oliveira Rezende Júnior C. Synthesis, Design, and Structure-Activity Relationship of a Benzenesulfonylpiperazine Series Against Trypanosoma Cruzi. Chemmedchem. PMID 35993440 DOI: 10.1002/cmdc.202200211 |
0.324 |
|
| 2022 |
Santos LH, Kronenberger T, Almeida RG, Silva EB, Rocha REO, Oliveira JC, Barreto LV, Skinner D, Fajtová P, Giardini MA, Woodworth B, Bardine C, Lourenço AL, Craik CS, Poso A, ... ... Ferreira RS, et al. Structure-Based Identification of Naphthoquinones and Derivatives as Novel Inhibitors of Main Protease M and Papain-like Protease PL of SARS-CoV-2. Journal of Chemical Information and Modeling. PMID 35960688 DOI: 10.1021/acs.jcim.2c00693 |
0.339 |
|
| 2022 |
Santos LH, Kronenberger T, Almeida RG, Silva EB, Rocha REO, Oliveira JC, Barreto LV, Skinner D, Fajtová P, Giardini MA, Woodworth B, Bardine C, Lourenço AL, Craik CS, Poso A, ... ... Ferreira RS, et al. Structure-based identification of naphthoquinones and derivatives as novel inhibitors of main protease Mpro and papain-like protease PLpro of SARS-CoV-2. Biorxiv : the Preprint Server For Biology. PMID 35018373 DOI: 10.1101/2022.01.05.475095 |
0.394 |
|
| 2021 |
Pauli I, Rezende CO, Slafer BW, Dessoy MA, de Souza ML, Ferreira LLG, Adjanohun ALM, Ferreira RS, Magalhães LG, Krogh R, Michelan-Duarte S, Del Pintor RV, da Silva FBR, Cruz FC, Dias LC, et al. Multiparameter Optimization of Trypanocidal Cruzain Inhibitors With Activity and Favorable Pharmacokinetics. Frontiers in Pharmacology. 12: 774069. PMID 35069198 DOI: 10.3389/fphar.2021.774069 |
0.333 |
|
| 2021 |
Barbosa da Silva E, Rocha DA, Fortes IS, Yang W, Monti L, Siqueira-Neto JL, Caffrey CR, McKerrow J, Andrade SF, Ferreira RS. Structure-Based Optimization of Quinazolines as Cruzain and CATL Inhibitors. Journal of Medicinal Chemistry. PMID 34461718 DOI: 10.1021/acs.jmedchem.1c01151 |
0.398 |
|
| 2020 |
Andrade MM, Martins LC, Marques GV, Silva CA, Faria G, Caldas S, Dos Santos JS, Leclercq SY, Maltarollo VG, Ferreira RS, Oliveira RB. Synthesis of quinoline derivatives as potential cysteine protease inhibitors. Future Medicinal Chemistry. PMID 32116030 DOI: 10.4155/Fmc-2019-0201 |
0.432 |
|
| 2019 |
Ferreira RAA, Pauli I, Sampaio TS, de Souza ML, Ferreira LLG, Magalhães LG, Rezende CO, Ferreira RS, Krogh R, Dias LC, Andricopulo AD. Structure-Based and Molecular Modeling Studies for the Discovery of Cyclic Imides as Reversible Cruzain Inhibitors With Potent Anti- Activity. Frontiers in Chemistry. 7: 798. PMID 31824926 DOI: 10.3389/Fchem.2019.00798 |
0.47 |
|
| 2019 |
Souza ML, de Oliveira Rezende Júnior C, Ferreira RS, Espinoza Chávez RM, Ferreira LLG, Slafer BW, Magalhaes LG, Krogh R, Oliva G, Cruz FC, Dias L, Andricopulo AD. Discovery of Potent, Reversible and Competitive Cruzain Inhibitors with Trypanocidal Activity: A Structure-Based Drug Design Approach. Journal of Chemical Information and Modeling. PMID 31765144 DOI: 10.1021/Acs.Jcim.9B00802 |
0.43 |
|
| 2019 |
Pereira GA, Santos LH, Wang SC, Martins LC, Villela FS, Liao W, Dessoy MA, Dias LC, Andricopulo AD, Costa MA, Nagem RA, Caffrey CR, Liedl KR, Caffarena ER, Ferreira RS. Benzimidazole inhibitors of the major cysteine protease of . Future Medicinal Chemistry. 11: 1537-1551. PMID 31469332 DOI: 10.4155/Fmc-2018-0523 |
0.459 |
|
| 2019 |
Santos LHS, Ferreira RS, Caffarena ER. Integrating Molecular Docking and Molecular Dynamics Simulations. Methods in Molecular Biology (Clifton, N.J.). 2053: 13-34. PMID 31452096 DOI: 10.1007/978-1-4939-9752-7_2 |
0.43 |
|
| 2019 |
Cardoso MVO, Oliveira Filho GB, Siqueira LRP, Espíndola JWP, Silva EBD, Mendes APO, Pereira VRA, Castro MCAB, Ferreira RS, Villela FS, Costa FMRD, Meira CS, Moreira DRM, Soares MBP, Leite ACL. 2-(phenylthio)ethylidene derivatives as anti-Trypanosoma cruzi compounds: Structural design, synthesis and antiparasitic activity. European Journal of Medicinal Chemistry. 180: 191-203. PMID 31306906 DOI: 10.1016/J.Ejmech.2019.07.018 |
0.418 |
|
| 2019 |
Pereira GAN, da Silva EB, Braga SFP, Leite PG, Martins LC, Vieira RP, Soh WT, Villela FS, Costa FMR, Ray D, de Andrade SF, Brandstetter H, Oliveira RB, Caffrey CR, Machado FS, ... Ferreira RS, et al. Discovery and characterization of trypanocidal cysteine protease inhibitors from the 'malaria box'. European Journal of Medicinal Chemistry. 179: 765-778. PMID 31284086 DOI: 10.1016/J.Ejmech.2019.06.062 |
0.518 |
|
| 2019 |
Barbosa da Silva E, Dall E, Briza P, Brandstetter H, Ferreira RS. Cruzain structures: apocruzain and cruzain bound to S-methyl thiomethanesulfonate and implications for drug design. Acta Crystallographica. Section F, Structural Biology Communications. 75: 419-427. PMID 31204688 DOI: 10.1107/S2053230X19006320 |
0.381 |
|
| 2019 |
Fahel JS, Vieira RP, Marinho FV, Santos VC, de Assis JV, Corsetti PP, Ferreira RS, de Almeida MV, Oliveira SC. JVA, an isoniazid analogue, is a bioactive compound against a clinical isolate of the Mycobacterium avium complex. Tuberculosis (Edinburgh, Scotland). 115: 108-112. PMID 30948164 DOI: 10.1016/J.Tube.2019.03.002 |
0.301 |
|
| 2019 |
Fassio AV, Santos LH, Silveira SA, Ferreira RS, de Melo-Minardi RC. nAPOLI: a graph-based strategy to detect and visualize conserved protein-ligand interactions in large-scale. Ieee/Acm Transactions On Computational Biology and Bioinformatics. PMID 30629512 DOI: 10.1109/Tcbb.2019.2892099 |
0.332 |
|
| 2018 |
Santos LH, Waldner BJ, Fuchs JE, Pereira GA, Liedl KR, Caffarena E, Ferreira RS. Understanding structure-activity relationships for trypanosomal cysteine protease inhibitors by simulations and free energy calculations. Journal of Chemical Information and Modeling. PMID 30532974 DOI: 10.1021/Acs.Jcim.8B00557 |
0.455 |
|
| 2018 |
Rocha DA, Silva EB, Fortes IS, Lopes MS, Ferreira RS, Andrade SF. Synthesis and structure-activity relationship studies of cruzain and rhodesain inhibitors. European Journal of Medicinal Chemistry. 157: 1426-1459. PMID 30282318 DOI: 10.1016/J.Ejmech.2018.08.079 |
0.448 |
|
| 2018 |
Moreira GA, de Almeida Lima GD, Siqueira RP, de Andrade Barros MV, Adjanohoun ALM, Santos VC, de Almeida Alves Barbosa É, Loterio RK, de Paiva JC, Gonçalves VHS, de Souza Viol LC, de Almeida Marques da Silva E, Júnior AS, Almeida MR, Fietto JLR, ... ... Ferreira RS, et al. Antimetastatic effect of the pharmacological inhibition of serine/arginine-rich protein kinases (SRPK) in murine melanoma. Toxicology and Applied Pharmacology. PMID 30138656 DOI: 10.1016/J.Taap.2018.08.012 |
0.388 |
|
| 2018 |
Ferreira LLG, Ferreira RS, Palomino DL, Andricopulo AD. Structure-Based Virtual Screening and Biochemical Evaluation for the Identification of Novel Trypanosoma Brucei Aldolase Inhibitors. Current Topics in Medicinal Chemistry. PMID 29701141 DOI: 10.2174/1568026618666180427150428 |
0.522 |
|
| 2018 |
Martins LC, Torres PHM, de Oliveira RB, Pascutti PG, Cino EA, Ferreira RS. Investigation of the binding mode of a novel cruzain inhibitor by docking, molecular dynamics, ab initio and MM/PBSA calculations. Journal of Computer-Aided Molecular Design. PMID 29564808 DOI: 10.1007/S10822-018-0112-3 |
0.326 |
|
| 2018 |
Oliveira AFCDS, de Souza APM, de Oliveira AS, da Silva ML, de Oliveira FM, Santos EG, da Silva ÍEP, Ferreira RS, Villela FS, Martins FT, Leal DHS, Vaz BG, Teixeira RR, de Paula SO. Zirconium catalyzed synthesis of 2-arylidene Indan-1,3-diones and evaluation of their inhibitory activity against NS2B-NS3 WNV protease. European Journal of Medicinal Chemistry. 149: 98-109. PMID 29499491 DOI: 10.1016/J.Ejmech.2018.02.037 |
0.37 |
|
| 2018 |
Teixeira RR, Gazolla PAR, da Silva AM, Borsodi MPG, Bergmann BR, Ferreira RS, Vaz BG, Vasconcelos GA, Lima WP. Synthesis and leishmanicidal activity of eugenol derivatives bearing 1,2,3-triazole functionalities. European Journal of Medicinal Chemistry. 146: 274-286. PMID 29407957 DOI: 10.1016/J.Ejmech.2018.01.046 |
0.384 |
|
| 2017 |
de Oliveira Filho GB, Cardoso MVO, Espíndola JWP, Oliveira E Silva DA, Ferreira RS, Coelho PL, Anjos PSD, Santos ES, Meira CS, Moreira DRM, Soares MBP, Leite ACL. Structural design, synthesis and pharmacological evaluation of thiazoles against Trypanosoma cruzi. European Journal of Medicinal Chemistry. 141: 346-361. PMID 29031078 DOI: 10.1016/J.Ejmech.2017.09.047 |
0.439 |
|
| 2017 |
Vieira RP, Santos VC, Ferreira RS. Structure-Based Approaches Targeting Parasite Cysteine Proteases. Current Medicinal Chemistry. PMID 28799498 DOI: 10.2174/0929867324666170810165302 |
0.42 |
|
| 2017 |
Pauli I, Ferreira LG, de Souza ML, Oliva G, Ferreira RS, Dessoy MA, Slafer BW, Dias LC, Andricopulo AD. Molecular modeling and structure-activity relationships for a series of benzimidazole derivatives as cruzain inhibitors. Future Medicinal Chemistry. PMID 28509592 DOI: 10.4155/Fmc-2016-0236 |
0.429 |
|
| 2017 |
da Silva EB, Oliveira E Silva DA, Oliveira AR, da Silva Mendes CH, Dos Santos TA, da Silva AC, de Castro MC, Ferreira RS, Moreira DR, Cardoso MV, de Simone CA, Pereira VR, Leite AC. Desing and synthesis of potent anti-Trypanosoma cruzi agents new thiazoles derivatives which induce apoptotic parasite death. European Journal of Medicinal Chemistry. 130: 39-50. PMID 28242550 DOI: 10.1016/J.Ejmech.2017.02.026 |
0.423 |
|
| 2017 |
Braga SF, Martins LC, da Silva EB, Sales Júnior PA, Murta SM, Romanha AJ, Soh WT, Brandstetter H, Ferreira RS, de Oliveira RB. Synthesis and biological evaluation of potential inhibitors of the cysteine proteases cruzain and rhodesain designed by molecular simplification. Bioorganic & Medicinal Chemistry. PMID 28215783 DOI: 10.1016/J.Bmc.2017.02.009 |
0.444 |
|
| 2016 |
Silva-Júnior EF, Silva EP, França PH, Silva JP, Barreto EO, Silva EB, Ferreira RS, Gatto CC, Moreira DR, Siqueira-Neto JL, Mendonça-Júnior FJ, Lima MC, Bortoluzzi JH, Scotti MT, Scotti L, et al. Design, synthesis, molecular docking and biological evaluation of thiophen-2-iminothiazolidine derivatives for use against Trypanosoma cruzi. Bioorganic & Medicinal Chemistry. PMID 27475533 DOI: 10.1016/J.Bmc.2016.07.013 |
0.428 |
|
| 2016 |
de Moraes Gomes PA, de Oliveira Barbosa M, Farias Santiago E, de Oliveira Cardoso MV, Capistrano Costa NT, Hernandes MZ, Moreira DR, da Silva AC, Dos Santos TA, Pereira VR, Brayner Dos Santosd FA, do Nascimento Pereira GA, Ferreira RS, Leite AC. New 1,3-thiazole derivatives and their biological and ultrastructural effects on Trypanosoma cruzi. European Journal of Medicinal Chemistry. 121: 387-398. PMID 27295485 DOI: 10.1016/J.Ejmech.2016.05.050 |
0.425 |
|
| 2016 |
Vital DG, Damasceno F, Rapado LN, Silber AM, Vilella FS, Ferreira RS, Maltarollo VG, Trossini GH. Aplication of bioisosterism in design of the semicarbazone derivatives: A theoretical and experimental study. Journal of Biomolecular Structure & Dynamics. 1-62. PMID 27064715 DOI: 10.1080/07391102.2016.1176603 |
0.44 |
|
| 2016 |
de Souza RA, Díaz N, Nagem RA, Ferreira RS, Suárez D. Unraveling the distinctive features of hemorrhagic and non-hemorrhagic snake venom metalloproteinases using molecular simulations. Journal of Computer-Aided Molecular Design. 30: 69-83. PMID 26676823 DOI: 10.1007/S10822-015-9889-5 |
0.329 |
|
| 2015 |
Santos LH, Ferreira RS, Caffarena ER. Computational drug design strategies applied to the modelling of human immunodeficiency virus-1 reverse transcriptase inhibitors. MemóRias Do Instituto Oswaldo Cruz. 110: 847-64. PMID 26560977 DOI: 10.1590/0074-02760150239 |
0.346 |
|
| 2015 |
de Oliveira Filho GB, de Oliveira Cardoso MV, Espíndola JW, Ferreira LF, de Simone CA, Ferreira RS, Coelho PL, Meira CS, Magalhaes Moreira DR, Soares MB, Lima Leite AC. Structural design, synthesis and pharmacological evaluation of 4-thiazolidinones against Trypanosoma cruzi. Bioorganic & Medicinal Chemistry. PMID 26549870 DOI: 10.1016/J.Bmc.2015.10.048 |
0.446 |
|
| 2015 |
Espíndola JW, Cardoso MV, Filho GB, Oliveira E Silva DA, Moreira DR, Bastos TM, Simone CA, Soares MB, Villela FS, Ferreira RS, Castro MC, Pereira VR, Murta SM, Sales Junior PA, Romanha AJ, et al. Synthesis and structure-activity relationship study of a new series of antiparasitic aryloxyl thiosemicarbazones inhibiting Trypanosoma cruzi cruzain. European Journal of Medicinal Chemistry. 101: 818-35. PMID 26231082 DOI: 10.1016/J.Ejmech.2015.06.048 |
0.451 |
|
| 2015 |
Radusky LG, Hassan S, Lanzarotti E, Tiwari S, Jamal S, Ali J, Ali A, Ferreira R, Barh D, Silva A, Turjanski AG, Azevedo VA. An integrated structural proteomics approach along the druggable genome of Corynebacterium pseudotuberculosis species for putative druggable targets. Bmc Genomics. 16: S9. PMID 26041381 DOI: 10.1186/1471-2164-16-S5-S9 |
0.341 |
|
| 2015 |
Folador EL, Junior AF, Tiwari S, Jamal SB, Ferreira RS, Barh D, Ghosh P, Silva A, Azevedo V. In Silico Protein-protein Interactions: Avoiding Data and Method Biases Over Sensitivity and Specificity. Current Protein & Peptide Science. PMID 25961403 DOI: 10.2174/1389203716666150505235437 |
0.301 |
|
| 2015 |
Fonseca NC, da Cruz LF, da Silva Villela F, do Nascimento Pereira GA, de Siqueira-Neto JL, Kellar D, Suzuki BM, Ray D, de Souza TB, Alves RJ, Sales Júnior PA, Romanha AJ, Murta SM, McKerrow JH, Caffrey CR, ... ... Ferreira RS, et al. Synthesis of a sugar-based thiosemicarbazone series and structure-activity relationship versus the parasite cysteine proteases rhodesain, cruzain, and Schistosoma mansoni cathepsin B1. Antimicrobial Agents and Chemotherapy. 59: 2666-77. PMID 25712353 DOI: 10.1128/Aac.04601-14 |
0.466 |
|
| 2014 |
Hassan SS, Tiwari S, Guimarães LC, Jamal SB, Folador E, Sharma NB, de Castro Soares S, Almeida S, Ali A, Islam A, Póvoa FD, de Abreu VA, Jain N, Bhattacharya A, Juneja L, ... ... Ferreira RS, et al. Proteome scale comparative modeling for conserved drug and vaccine targets identification in Corynebacterium pseudotuberculosis. Bmc Genomics. 15: S3. PMID 25573232 DOI: 10.1186/1471-2164-15-S7-S3 |
0.406 |
|
| 2014 |
Folador EL, Hassan SS, Lemke N, Barh D, Silva A, Ferreira RS, Azevedo V. An improved interolog mapping-based computational prediction of protein-protein interactions with increased network coverage. Integrative Biology : Quantitative Biosciences From Nano to Macro. 6: 1080-7. PMID 25209055 DOI: 10.1039/C4Ib00136B |
0.307 |
|
| 2014 |
Cardoso MV, de Siqueira LR, da Silva EB, Costa LB, Hernandes MZ, Rabello MM, Ferreira RS, da Cruz LF, Moreira DR, Pereira VR, de Castro MC, Bernhardt PV, Leite AC. 2-Pyridyl thiazoles as novel anti-Trypanosoma cruzi agents: structural design, synthesis and pharmacological evaluation. European Journal of Medicinal Chemistry. 86: 48-59. PMID 25147146 DOI: 10.1016/J.Ejmech.2014.08.012 |
0.443 |
|
| 2014 |
Magalhaes Moreira DR, de Oliveira AD, Teixeira de Moraes Gomes PA, de Simone CA, Villela FS, Ferreira RS, da Silva AC, dos Santos TA, Brelaz de Castro MC, Pereira VR, Leite AC. Conformational restriction of aryl thiosemicarbazones produces potent and selective anti-Trypanosoma cruzi compounds which induce apoptotic parasite death. European Journal of Medicinal Chemistry. 75: 467-78. PMID 24561675 DOI: 10.1016/J.Ejmech.2014.02.001 |
0.4 |
|
| 2014 |
Ferreira RS, Dessoy MA, Pauli I, Souza ML, Krogh R, Sales AI, Oliva G, Dias LC, Andricopulo AD. Synthesis, biological evaluation, and structure-activity relationships of potent noncovalent and nonpeptidic cruzain inhibitors as anti-Trypanosoma cruzi agents. Journal of Medicinal Chemistry. 57: 2380-92. PMID 24533839 DOI: 10.1021/Jm401709B |
0.449 |
|
| 2014 |
Braga SF, Alves ÉV, Ferreira RS, Fradico JR, Lage PS, Duarte MC, Ribeiro TG, Júnior PA, Romanha AJ, Tonini ML, Steindel M, Coelho EF, de Oliveira RB. Synthesis and evaluation of the antiparasitic activity of bis-(arylmethylidene) cycloalkanones. European Journal of Medicinal Chemistry. 71: 282-9. PMID 24321832 DOI: 10.1016/J.Ejmech.2013.11.011 |
0.418 |
|
| 2014 |
Moreira DR, Leite AC, Cardoso MV, Srivastava RM, Hernandes MZ, Rabello MM, da Cruz LF, Ferreira RS, de Simone CA, Meira CS, Guimaraes ET, da Silva AC, dos Santos TA, Pereira VR, Soares MB. Structural design, synthesis and structure-activity relationships of thiazolidinones with enhanced anti-Trypanosoma cruzi activity. Chemmedchem. 9: 177-88. PMID 24203393 DOI: 10.1002/Cmdc.201300354 |
0.423 |
|
| 2014 |
Ferreira RS, Andricopulo AD. Structure-based drug design to overcome drug resistance: challenges and opportunities. Current Pharmaceutical Design. 20: 687-93. PMID 23688077 DOI: 10.2174/138161282005140214161949 |
0.332 |
|
| 2012 |
Moreira DR, Costa SP, Hernandes MZ, Rabello MM, de Oliveira Filho GB, de Melo CM, da Rocha LF, de Simone CA, Ferreira RS, Fradico JR, Meira CS, Guimarães ET, Srivastava RM, Pereira VR, Soares MB, et al. Structural investigation of anti-Trypanosoma cruzi 2-iminothiazolidin-4-ones allows the identification of agents with efficacy in infected mice. Journal of Medicinal Chemistry. 55: 10918-36. PMID 23167554 DOI: 10.1021/Jm301518V |
0.402 |
|
| 2012 |
dos Santos Filho JM, Moreira DR, de Simone CA, Ferreira RS, McKerrow JH, Meira CS, Guimarães ET, Soares MB. Optimization of anti-Trypanosoma cruzi oxadiazoles leads to identification of compounds with efficacy in infected mice. Bioorganic & Medicinal Chemistry. 20: 6423-33. PMID 23006639 DOI: 10.1016/J.Bmc.2012.08.047 |
0.415 |
|
| 2011 |
Ferreira RS, Guido RV, Andricopulo AD, Oliva G. In silico screening strategies for novel inhibitors of parasitic diseases. Expert Opinion On Drug Discovery. 6: 481-9. PMID 22646074 DOI: 10.1517/17460441.2011.563297 |
0.37 |
|
| 2011 |
Ferreira RS, Oliva G, Andricopulo AD. Integração das técnicas de triagem virtual e triagem biológica automatizada em alta escala: oportunidades e desafios em P&D de fármacos QuíMica Nova. 34: 1770-1778. DOI: 10.1590/S0100-40422011001000010 |
0.411 |
|
| 2011 |
Ferreira RS, Oliva G, Andricopulo AD. Integrating virtual and high-throughput screening: Opportunities and challenges in drug research and development | Integração das técnicas de triagem virtual e triagem biológica automatizada em alta escala: Oportunidades e desafios em P&D de fármacos Quimica Nova. 34: 1770-1778. |
0.312 |
|
| 2010 |
Hernandes MZ, Rabello MM, Leite AC, Cardoso MV, Moreira DR, Brondani DJ, Simone CA, Reis LC, Souza MA, Pereira VR, Ferreira RS, McKerrow JH. Studies toward the structural optimization of novel thiazolylhydrazone-based potent antitrypanosomal agents. Bioorganic & Medicinal Chemistry. 18: 7826-35. PMID 20961766 DOI: 10.1016/J.Bmc.2010.09.056 |
0.459 |
|
| 2010 |
Ferreira RS, Simeonov A, Jadhav A, Eidam O, Mott BT, Keiser MJ, McKerrow JH, Maloney DJ, Irwin JJ, Shoichet BK. Complementarity between a docking and a high-throughput screen in discovering new cruzain inhibitors. Journal of Medicinal Chemistry. 53: 4891-905. PMID 20540517 DOI: 10.1021/Jm100488W |
0.714 |
|
| 2010 |
Mott BT, Ferreira RS, Simeonov A, Jadhav A, Ang KK, Leister W, Shen M, Silveira JT, Doyle PS, Arkin MR, McKerrow JH, Inglese J, Austin CP, Thomas CJ, Shoichet BK, et al. Identification and optimization of inhibitors of Trypanosomal cysteine proteases: cruzain, rhodesain, and TbCatB. Journal of Medicinal Chemistry. 53: 52-60. PMID 19908842 DOI: 10.1021/Jm901069A |
0.613 |
|
| 2010 |
Jadhav A, Ferreira RS, Klumpp C, Mott BT, Austin CP, Inglese J, Thomas CJ, Maloney DJ, Shoichet BK, Simeonov A. Quantitative analyses of aggregation, autofluorescence, and reactivity artifacts in a screen for inhibitors of a thiol protease. Journal of Medicinal Chemistry. 53: 37-51. PMID 19908840 DOI: 10.1021/Jm901070C |
0.611 |
|
| 2009 |
Bryant C, Kerr ID, Debnath M, Ang KK, Ratnam J, Ferreira RS, Jaishankar P, Zhao D, Arkin MR, McKerrow JH, Brinen LS, Renslo AR. Novel non-peptidic vinylsulfones targeting the S2 and S3 subsites of parasite cysteine proteases. Bioorganic & Medicinal Chemistry Letters. 19: 6218-21. PMID 19773167 DOI: 10.1016/J.Bmcl.2009.08.098 |
0.317 |
|
| 2009 |
Mckerrow JH, Doyle PS, Engel JC, Podust LM, Robertson SA, Ferreira R, Saxton T, Arkin M, Kerr ID, Brinen LS, Craik CS. Two approaches to discovering and developing new drugs for Chagas disease Memorias Do Instituto Oswaldo Cruz. 104: 263-269. PMID 19753483 DOI: 10.1590/S0074-02762009000900034 |
0.402 |
|
| 2009 |
Kolb P, Ferreira RS, Irwin JJ, Shoichet BK. Docking and chemoinformatic screens for new ligands and targets. Current Opinion in Biotechnology. 20: 429-36. PMID 19733475 DOI: 10.1016/J.Copbio.2009.08.003 |
0.711 |
|
| 2009 |
Ferreira RS, Bryant C, Ang KK, McKerrow JH, Shoichet BK, Renslo AR. Divergent modes of enzyme inhibition in a homologous structure-activity series. Journal of Medicinal Chemistry. 52: 5005-8. PMID 19637873 DOI: 10.1021/Jm9009229 |
0.597 |
|
| 2009 |
Teotico DG, Babaoglu K, Rocklin GJ, Ferreira RS, Giannetti AM, Shoichet BK. Docking for fragment inhibitors of AmpC beta-lactamase. Proceedings of the National Academy of Sciences of the United States of America. 106: 7455-60. PMID 19416920 DOI: 10.1073/Pnas.0813029106 |
0.727 |
|
| 2008 |
De Oliveira RB, Zani CL, Ferreira RS, Leite RS, Alves TMA, Da Silva THA, Romanha AJ. Synthesis, biological evaluation and molecular modeling of arylfurans as potential trypanothione reductase inhibitors | Síntese, avaliação biológica e modelagem molecular de arilfuranos como inibidores da enzima tripanotiona redutase Quimica Nova. 31: 261-267. DOI: 10.1590/S0100-40422008000200013 |
0.38 |
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