John N. Alumasa, Ph.D. - Publications

Affiliations: 
2010 Chemistry Georgetown University, Washington, DC 
Area:
Parasitology, Biochemistry, Molecular Biology

20 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Aron ZD, Mehrani A, Hoffer ED, Connolly KL, Srinivas P, Torhan MC, Alumasa JN, Cabrera M, Hosangadi D, Barbor JS, Cardinale SC, Kwasny SM, Morin LR, Butler MM, Opperman TJ, et al. trans-Translation inhibitors bind to a novel site on the ribosome and clear Neisseria gonorrhoeae in vivo. Nature Communications. 12: 1799. PMID 33741965 DOI: 10.1038/s41467-021-22012-7  0.522
2019 Huang Y, Alumasa JN, Callaghan LT, Baugh RS, Rae CD, Keiler KC, McGillivray SM. A Small-Molecule Inhibitor of -Translation Synergistically Interacts with Cathelicidin Antimicrobial Peptides To Impair Survival of Staphylococcus aureus. Antimicrobial Agents and Chemotherapy. 63. PMID 30917982 DOI: 10.1128/Aac.02362-18  0.391
2017 Alumasa JN, Manzanillo PS, Peterson ND, Lundrigan T, Baughn AD, Cox JS, Keiler KC. Ribosome Rescue Inhibitors Kill Actively Growing and Non-replicating Persister Mycobacterium tuberculosis Cells. Acs Infectious Diseases. PMID 28762275 DOI: 10.1021/Acsinfecdis.7B00028  0.412
2017 Alumasa JN, Goralski TDP, Keiler KC. Tetrazole-Based trans-Translation Inhibitors Kill Bacillus anthracis Spores to Protect Host Cells. Antimicrobial Agents and Chemotherapy. PMID 28760903 DOI: 10.1128/Aac.01199-17  0.356
2016 Goralski TD, Dewan KK, Alumasa JN, Avanzato V, Place DE, Markley RL, Katkere B, Rabadi SM, Bakshi CS, Keiler KC, Kirimanjeswara GS. Inhibitors of ribosome rescue arrest growth of Francisella tularensis at all stages of intracellular replication. Antimicrobial Agents and Chemotherapy. PMID 26953190 DOI: 10.1128/Aac.03089-15  0.33
2015 Alumasa JN, Keiler KC. Clicking on trans-translation drug targets. Frontiers in Microbiology. 6: 498. PMID 26042115 DOI: 10.3389/Fmicb.2015.00498  0.325
2015 El-Mowafi SA, Sineva E, Alumasa JN, Nicoloff H, Tomsho JW, Ades SE, Keiler KC. Identification of inhibitors of a bacterial sigma factor using a new high-throughput screening assay. Antimicrobial Agents and Chemotherapy. 59: 193-205. PMID 25331704 DOI: 10.1128/Aac.03979-14  0.332
2014 El-Mowafi SA, Alumasa JN, Ades SE, Keiler KC. Cell-based assay to identify inhibitors of the Hfq-sRNA regulatory pathway. Antimicrobial Agents and Chemotherapy. 58: 5500-9. PMID 25001303 DOI: 10.1128/Aac.03311-14  0.341
2013 Ramadoss NS, Alumasa JN, Cheng L, Wang Y, Li S, Chambers BS, Chang H, Chatterjee AK, Brinker A, Engels IH, Keiler KC. Small molecule inhibitors of trans-translation have broad-spectrum antibiotic activity. Proceedings of the National Academy of Sciences of the United States of America. 110: 10282-7. PMID 23733947 DOI: 10.1073/Pnas.1302816110  0.414
2013 Gorka AP, Alumasa JN, Sherlach KS, Jacobs LM, Nickley KB, Brower JP, de Dios AC, Roepe PD. Cytostatic versus cytocidal activities of chloroquine analogues and inhibition of hemozoin crystal growth. Antimicrobial Agents and Chemotherapy. 57: 356-64. PMID 23114783 DOI: 10.1128/Aac.01709-12  0.691
2012 McGillivray SM, Tran DN, Ramadoss NS, Alumasa JN, Okumura CY, Sakoulas G, Vaughn MM, Zhang DX, Keiler KC, Nizet V. Pharmacological inhibition of the ClpXP protease increases bacterial susceptibility to host cathelicidin antimicrobial peptides and cell envelope-active antibiotics. Antimicrobial Agents and Chemotherapy. 56: 1854-61. PMID 22252821 DOI: 10.1128/Aac.05131-11  0.389
2011 Pan E, Gorka AP, Alumasa JN, Slebodnick C, Harinantenaina L, Brodie PJ, Roepe PD, Randrianaivo R, Birkinshaw C, Kingston DG. Antiplasmodial and antiproliferative pseudoguaianolides of Athroisma proteiforme from the Madagascar Dry Forest. Journal of Natural Products. 74: 2174-80. PMID 21995542 DOI: 10.1021/Np200499D  0.685
2011 Alumasa JN, Gorka AP, Casabianca LB, Comstock E, de Dios AC, Roepe PD. The hydroxyl functionality and a rigid proximal N are required for forming a novel non-covalent quinine-heme complex. Journal of Inorganic Biochemistry. 105: 467-75. PMID 20864177 DOI: 10.1016/J.Jinorgbio.2010.08.011  0.691
2009 Iwaniuk DP, Whetmore ED, Rosa N, Ekoue-Kovi K, Alumasa J, de Dios AC, Roepe PD, Wolf C. Synthesis and antimalarial activity of new chloroquine analogues carrying a multifunctional linear side chain. Bioorganic & Medicinal Chemistry. 17: 6560-6. PMID 19703776 DOI: 10.1016/J.Bmc.2009.08.003  0.647
2009 Hou Y, Cao S, Brodie PJ, Callmander MW, Ratovoson F, Rakotobe EA, Rasamison VE, Ratsimbason M, Alumasa JN, Roepe PD, Kingston DG. Antiproliferative and antimalarial anthraquinones of Scutia myrtina from the Madagascar forest. Bioorganic & Medicinal Chemistry. 17: 2871-6. PMID 19282186 DOI: 10.1016/J.Bmc.2009.02.022  0.634
2009 Casabianca LB, Kallgren JB, Natarajan JK, Alumasa JN, Roepe PD, Wolf C, de Dios AC. Antimalarial drugs and heme in detergent micelles: An NMR study. Journal of Inorganic Biochemistry. 103: 745-8. PMID 19223262 DOI: 10.1016/J.Jinorgbio.2009.01.013  0.589
2009 Ekoue-Kovi K, Yearick K, Iwaniuk DP, Natarajan JK, Alumasa J, de Dios AC, Roepe PD, Wolf C. Synthesis and antimalarial activity of new 4-amino-7-chloroquinolyl amides, sulfonamides, ureas and thioureas. Bioorganic & Medicinal Chemistry. 17: 270-83. PMID 19041248 DOI: 10.1016/J.Bmc.2008.11.009  0.641
2008 Casabianca LB, An D, Natarajan JK, Alumasa JN, Roepe PD, Wolf C, de Dios AC. Quinine and chloroquine differentially perturb heme monomer-dimer equilibrium. Inorganic Chemistry. 47: 6077-81. PMID 18533646 DOI: 10.1021/Ic800440D  0.555
2008 Natarajan JK, Alumasa JN, Yearick K, Ekoue-Kovi KA, Casabianca LB, de Dios AC, Wolf C, Roepe PD. 4-N-, 4-S-, and 4-O-chloroquine analogues: influence of side chain length and quinolyl nitrogen pKa on activity vs chloroquine resistant malaria. Journal of Medicinal Chemistry. 51: 3466-79. PMID 18512900 DOI: 10.1021/Jm701478A  0.626
2008 Yearick K, Ekoue-Kovi K, Iwaniuk DP, Natarajan JK, Alumasa J, de Dios AC, Roepe PD, Wolf C. Overcoming drug resistance to heme-targeted antimalarials by systematic side chain variation of 7-chloro-4-aminoquinolines. Journal of Medicinal Chemistry. 51: 1995-8. PMID 18345611 DOI: 10.1021/Jm800106U  0.633
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