Fred Levine - Publications

Affiliations: 
Bioengineering University of California, San Diego, La Jolla, CA 
Area:
Biomedical Engineering

66 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Levine F. Approaches to Inducing β-Cell Regeneration. Biomedicines. 10. PMID 35327373 DOI: 10.3390/biomedicines10030571  0.329
2018 Lee SH, Hao E, Scharp D, Levine F. Insulin Acts as a Repressive Factor to Inhibit the Ability of PAR2 to Induce Islet Cell Transdifferentiation. Islets. 1-24. PMID 29723131 DOI: 10.1080/19382014.2018.1472839  0.513
2017 Lee SH, Cunha D, Piermarocchi C, Paternostro G, Pinkerton A, Ladriere L, Marchetti P, Eizirik DL, Cnop M, Levine F. High-Throughput Screening and Bioinformatic Analysis to Ascertain Compounds that Prevent Saturated Fatty Acid-Induced β-Cell Apoptosis. Biochemical Pharmacology. PMID 28522407 DOI: 10.1016/J.Bcp.2017.05.007  0.442
2016 Piran R, Lee SH, Kuss P, Hao E, Newlin R, Millán JL, Levine F. PAR2 regulates regeneration, transdifferentiation, and death. Cell Death & Disease. 7: e2452. PMID 27809303 DOI: 10.1038/Cddis.2016.357  0.491
2014 Chung CH, Miller A, Panopoulos A, Hao E, Margolis R, Terskikh A, Levine F. Maternal embryonic leucine zipper kinase regulates pancreatic ductal, but not β-cell, regeneration. Physiological Reports. 2. PMID 25194022 DOI: 10.14814/Phy2.12131  0.512
2013 Lee SH, Piran R, Keinan E, Pinkerton A, Levine F. Induction of β-cell replication by a synthetic HNF4α antagonist. Stem Cells (Dayton, Ohio). 31: 2396-407. PMID 23922283 DOI: 10.1002/Stem.1496  0.5
2013 Hao E, Lee SH, Levine F. Efficient β-cell regeneration by a combination of neogenesis and replication following β-cell ablation and reversal of pancreatic duct ligation. Stem Cells (Dayton, Ohio). 31: 2388-95. PMID 23922239 DOI: 10.1002/Stem.1492  0.528
2013 Lee SH, Athavankar S, Cohen T, Piran R, Kiselyuk A, Levine F. Identification of alverine and benfluorex as HNF4α activators. Acs Chemical Biology. 8: 1730-6. PMID 23675775 DOI: 10.1021/Cb4000986  0.345
2012 Kiselyuk A, Lee SH, Farber-Katz S, Zhang M, Athavankar S, Cohen T, Pinkerton AB, Ye M, Bushway P, Richardson AD, Hostetler HA, Rodriguez-Lee M, Huang L, Spangler B, Smith L, ... ... Levine F, et al. HNF4α antagonists discovered by a high-throughput screen for modulators of the human insulin promoter. Chemistry & Biology. 19: 806-18. PMID 22840769 DOI: 10.1016/J.Chembiol.2012.05.014  0.411
2011 Tyrberg B, Miles P, Azizian KT, Denzel MS, Nieves ML, Monosov EZ, Levine F, Ranscht B. T-cadherin (Cdh13) in association with pancreatic β-cell granules contributes to second phase insulin secretion. Islets. 3: 327-37. PMID 21975561 DOI: 10.4161/Isl.3.6.17705  0.408
2011 Lee SH, Hao E, Levine F, Itkin-Ansari P. Id3 upregulates BrdU incorporation associated with a DNA damage response, not replication, in human pancreatic β-cells. Islets. 3: 358-66. PMID 21964314 DOI: 10.4161/Isl.3.6.17923  0.555
2011 Lee SH, Hao E, Levine F. β-Cell replication and islet neogenesis following partial pancreatectomy. Islets. 3: 188-95. PMID 21623169 DOI: 10.4161/Isl.3.4.16338  0.509
2011 Lee SH, Hao E, Kiselyuk A, Shapiro J, Shields DJ, Lowy A, Levine F, Itkin-Ansari P. The Id3/E47 axis mediates cell-cycle control in human pancreatic ducts and adenocarcinoma. Molecular Cancer Research : McR. 9: 782-90. PMID 21498546 DOI: 10.1158/1541-7786.Mcr-10-0535  0.51
2010 Lee SH, Itkin-Ansari P, Levine F. CENP-A, a protein required for chromosome segregation in mitosis, declines with age in islet but not exocrine cells. Aging. 2: 785-90. PMID 21068465  0.397
2010 Chung CH, Levine F. Adult pancreatic alpha-cells: a new source of cells for beta-cell regeneration. The Review of Diabetic Studies : Rds. 7: 124-31. PMID 21060971 DOI: 10.1900/RDS.2010.7.124  0.425
2010 Chung CH, Hao E, Piran R, Keinan E, Levine F. Pancreatic β-cell neogenesis by direct conversion from mature α-cells. Stem Cells (Dayton, Ohio). 28: 1630-8. PMID 20653050 DOI: 10.1002/Stem.482  0.446
2010 Kiselyuk A, Farber-Katz S, Cohen T, Lee SH, Geron I, Azimi B, Heynen-Genel S, Singer O, Price J, Mercola M, Itkin-Ansari P, Levine F. Phenothiazine neuroleptics signal to the human insulin promoter as revealed by a novel high-throughput screen. Journal of Biomolecular Screening. 15: 663-70. PMID 20547533 DOI: 10.1177/1087057110372257  0.494
2010 Chung CH, Levine F. Adult pancreatic alpha cells: A new source of cells for beta-cell regeneration Review of Diabetic Studies. 7: 120-127. DOI: 10.1900/RDS.2010.7.120  0.426
2009 Demeterco C, Hao E, Lee SH, Itkin-Ansari P, Levine F. Adult human β-cell neogenesis? Diabetes, Obesity and Metabolism. 11: 46-53. PMID 19817788 DOI: 10.1111/J.1463-1326.2009.01105.X  0.542
2009 Zhang SS, Hao E, Yu J, Liu W, Wang J, Levine F, Feng GS. Coordinated regulation by Shp2 tyrosine phosphatase of signaling events controlling insulin biosynthesis in pancreatic beta-cells. Proceedings of the National Academy of Sciences of the United States of America. 106: 7531-6. PMID 19380737 DOI: 10.1073/Pnas.0811715106  0.455
2008 Lee SH, Demeterco C, Geron I, Abrahamsson A, Levine F, Itkin-Ansari P. Islet specific Wnt activation in human type II diabetes. Experimental Diabetes Research. 2008: 728763. PMID 19165345 DOI: 10.1155/2008/728763  0.392
2008 Levine F, Itkin-Ansari P. beta-cell Regeneration: neogenesis, replication or both? Journal of Molecular Medicine (Berlin, Germany). 86: 247-58. PMID 17922102 DOI: 10.1007/S00109-007-0259-1  0.549
2007 Ball AJ, Abrahamsson AE, Tyrberg B, Itkin-Ansari P, Levine F. HES6 reverses nuclear reprogramming of insulin-producing cells following cell fusion. Biochemical and Biophysical Research Communications. 355: 331-7. PMID 17300753 DOI: 10.1016/J.Bbrc.2007.01.153  0.579
2006 Katkov II, Kim MS, Bajpai R, Altman YS, Mercola M, Loring JF, Terskikh AV, Snyder EY, Levine F. Cryopreservation by slow cooling with DMSO diminished production of Oct-4 pluripotency marker in human embryonic stem cells. Cryobiology. 53: 194-205. PMID 16839540 DOI: 10.1016/J.Cryobiol.2006.05.005  0.45
2006 Hao E, Tyrberg B, Itkin-Ansari P, Lakey JR, Geron I, Monosov EZ, Barcova M, Mercola M, Levine F. Beta-cell differentiation from nonendocrine epithelial cells of the adult human pancreas. Nature Medicine. 12: 310-6. PMID 16491084 DOI: 10.1038/Nm1367  0.578
2006 Katkov II, Isachenko V, Isachenko E, Kim MS, Lulat AG-I, Mackay AM, Levine F. Low- and high-temperature vitrification as a new approach to biostabilization of reproductive and progenitor cells International Journal of Refrigeration-Revue Internationale Du Froid. 29: 346-357. DOI: 10.1016/J.Ijrefrig.2005.11.004  0.399
2006 Katkov II, Kim MS, Karpova NS, Lulat AG, Cao C, Levine F, Terskikh AV, Loring JF, Snyder EY. 6. Cryobiology for stem cell therapy: Research overview Cryobiology. 53: 369-370. DOI: 10.1016/J.Cryobiol.2006.10.007  0.353
2005 Itkin-Ansari P, Marcora E, Geron I, Tyrberg B, Demeterco C, Hao E, Padilla C, Ratineau C, Leiter A, Lee JE, Levine F. NeuroD1 in the endocrine pancreas: localization and dual function as an activator and repressor. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 233: 946-53. PMID 15906379 DOI: 10.1002/Dvdy.20443  0.545
2005 Ball AJ, Levine F. Telomere-independent cellular senescence in human fetal cardiomyocytes. Aging Cell. 4: 21-30. PMID 15659210 DOI: 10.1111/J.1474-9728.2004.00137.X  0.493
2004 Levine F, Mercola M. No pancreatic endocrine stem cells? The New England Journal of Medicine. 351: 1024-6. PMID 15342812 DOI: 10.1056/Nejmcibr041779  0.532
2004 Itkin-Ansari P, Levine F. Sources of beta-cells for human cell-based therapies for diabetes. Cell Biochemistry and Biophysics. 40: 103-12. PMID 15289647 DOI: 10.1385/Cbb:40:3:109  0.593
2003 Itkin-Ansari P, Geron I, Hao E, Demeterco C, Tyrberg B, Levine F. Cell-based therapies for diabetes: progress towards a transplantable human beta cell line. Annals of the New York Academy of Sciences. 1005: 138-47. PMID 14679048 DOI: 10.1196/Annals.1288.015  0.611
2002 Demeterco C, Itkin-Ansari P, Tyrberg B, Ford LP, Jarvis RA, Levine F. c-Myc controls proliferation versus differentiation in human pancreatic endocrine cells. The Journal of Clinical Endocrinology and Metabolism. 87: 3475-85. PMID 12107268 DOI: 10.1210/Jcem.87.7.8700  0.511
2002 Tyrberg B, Anachkov KA, Dib SA, Wang-Rodriguez J, Yoon KH, Levine F. Islet expression of the DNA repair enzyme 8-oxoguanosine DNA glycosylase (Ogg1) in human type 2 diabetes. Bmc Endocrine Disorders. 2: 2. PMID 12003641 DOI: 10.1186/1472-6823-2-2  0.395
2001 Halvorsen T, Levine F. Diabetes mellitus-cell transplantation and gene therapy approaches Current Molecular Medicine. 1: 273-286. PMID 11899076 DOI: 10.2174/1566524013363951  0.74
2001 Gordon SL, Oppenheimer SR, Mackay AM, Brunnabend J, Puhlev I, Levine F. Recovery of human mesenchymal stem cells following dehydration and rehydration. Cryobiology. 43: 182-7. PMID 11846472 DOI: 10.1006/Cryo.2001.2361  0.465
2001 Lao G, Polayes D, Xia JL, Bloom FR, Levine F, Mansbridge J. Overexpression of trehalose synthase and accumulation of intracellular trehalose in 293H and 293FTetR:Hyg cells. Cryobiology. 43: 106-13. PMID 11846465 DOI: 10.1006/Cryo.2001.2354  0.37
2001 Tyrberg B, Levine F. Current and future treatment strategies for type 2 diabetes: The β-cell a therapeutic target Current Opinion in Investigational Drugs. 2: 1568-1574. PMID 11763159  0.326
2001 Puhlev I, Guo N, Brown DR, Levine F. Desiccation tolerance in human cells Cryobiology. 42: 207-217. PMID 11578120 DOI: 10.1006/Cryo.2001.2324  0.497
2001 Wood LD, Halvorsen TL, Dhar S, Baur JA, Pandita RK, Wright WE, Hande MP, Calaf G, Hei TK, Levine F, Shay JW, Wang JJ, Pandita TK. Characterization of ataxia telangiectasia fibroblasts with extended life-span through telomerase expression. Oncogene. 20: 278-88. PMID 11313956 DOI: 10.1038/Sj.Onc.1204072  0.717
2001 de la Tour D, Halvorsen T, Demeterco C, Tyrberg B, Itkin-Ansari P, Loy M, Yoo SJ, Hao E, Bossie S, Levine F. Beta-cell differentiation from a human pancreatic cell line in vitro and in vivo. Molecular Endocrinology (Baltimore, Md.). 15: 476-83. PMID 11222748 DOI: 10.1210/Mend.15.3.0604  0.774
2000 Beattie GM, Hayek A, Levine F. Growth and genetic modification of human beta-cells and beta-cell precursors Genetic Engineering. 22: 99-120. PMID 11501383 DOI: 10.1007/978-1-4615-4199-8_7  0.543
2000 Beattie GM, Leibowitz G, Lopez AD, Levine F, Hayek A. Protection from cell death in cultured human fetal pancreatic cells Cell Transplantation. 9: 431-438. PMID 10972342 DOI: 10.1177/096368970000900314  0.507
2000 Halvorsen TL, Beattie GM, Lopez AD, Hayek A, Levine F. Accelerated telomere shortening and senescence in human pancreatic islet cells stimulated to divide in vitro. The Journal of Endocrinology. 166: 103-9. PMID 10856888 DOI: 10.1677/Joe.0.1660103  0.775
2000 Itkin-Ansari P, Demeterco C, Bossie S, de la Tour DD, Beattie GM, Movassat J, Mally MI, Hayek A, Levine F. PDX-1 and cell-cell contact act in synergy to promote delta-cell development in a human pancreatic endocrine precursor cell line. Molecular Endocrinology (Baltimore, Md.). 14: 814-22. PMID 10847584 DOI: 10.1210/Mend.14.6.0476  0.563
2000 Guo N, Puhlev I, Brown DR, Mansbridge J, Levine F. Trehalose expression confers desiccation tolerance on human cells. Nature Biotechnology. 18: 168-71. PMID 10657122 DOI: 10.1038/72616  0.44
1999 Beattie GM, Itkin-Ansari P, Cirulli V, Leibowitz G, Lopez AD, Bossie S, Mally MI, Levine F, Hayek A. Sustained proliferation of PDX-1+ cells derived from human islets. Diabetes. 48: 1013-9. PMID 10331405 DOI: 10.2337/Diabetes.48.5.1013  0.611
1999 Levine F, Leibowitz G. Towards gene therapy of diabetes mellitus Molecular Medicine Today. 5: 165-171. PMID 10203749 DOI: 10.1016/S1357-4310(98)01425-7  0.479
1999 Leibowitz G, Beattie GM, Kafri T, Cirulli V, Lopez AD, Hayek A, Levine F. Gene transfer to human pancreatic endocrine cells using viral vectors Diabetes. 48: 745-753. PMID 10102690 DOI: 10.2337/Diabetes.48.4.745  0.441
1999 Halvorsen TL, Leibowitz G, Levine F. Telomerase activity is sufficient to allow transformed cells to escape from crisis. Molecular and Cellular Biology. 19: 1864-70. PMID 10022873 DOI: 10.1128/Mcb.19.3.1864  0.751
1999 Leibowitz G, Levine F. Gene therapy for type 1 and type 2 diabetes Diabetes Reviews. 7: 124-138.  0.375
1997 Levine F. Gene therapy for diabetes: Strategies for β-cell modification and replacement Diabetes/Metabolism Reviews. 13: 209-246. PMID 9509277 DOI: 10.1002/(Sici)1099-0895(199712)13:4<209::Aid-Dmr198>3.0.Co;2-N  0.479
1997 Sinclair AM, Agrawal YP, Elbar E, Agrawal R, Ho AD, Levine F. Interaction of vesicular stomatitis virus-G pseudotyped retrovirus with CD34+ and CD34+ CD38- hematopoietic progenitor cells. Gene Therapy. 4: 918-27. PMID 9349428 DOI: 10.1038/Sj.Gt.3300479  0.317
1997 Wang S, Beattie GM, Mally MI, Lopez AD, Hayek A, Levine F. Analysis of a human fetal pancreatic islet cell line Transplantation Proceedings. 29: 2219. PMID 9193600 DOI: 10.1016/S0041-1345(97)00306-0  0.444
1997 Wang S, Beattie GM, Mally MI, Cirulli V, Itkin-Ansari P, Lopez AD, Hayek A, Levine F. Isolation and characterization of a cell line from the epithelial cells of the human fetal pancreas. Cell Transplantation. 6: 59-67. PMID 9040956 DOI: 10.1016/S0963-6897(96)00120-0  0.544
1997 Wang S, Beattie GM, Hayek A, Levine F. Development of a VSV-G protein pseudotyped retroviral vector system expressing dominant oncogenes from a lacO-modified inducible LTR promoter. Gene. 182: 145-50. PMID 8982080 DOI: 10.1016/S0378-1119(96)00536-7  0.457
1996 Itkin-Ansari P, Bain G, Beattie GM, Murre C, Hayek A, Levine F. E2A gene products are not required for insulin gene expression Endocrinology. 137: 3540-3543. PMID 8754784 DOI: 10.1210/Endo.137.8.8754784  0.37
1996 Levine F, Wang S, Beattie GM, Mally MI, Cirulli V, Lopez AD, Hayek A. Development and characterization of cell lines from human pancreatic β-cells and β-cell precurosrs using retroviral vectors expressing SV40 T-antigen and H-rasval12 Cell Transplantation. 5: 74. DOI: 10.1016/0963-6897(96)82302-5  0.47
1994 Beattie GM, Levine F, Mally MI, Otonkoski T, O'Brien JS, Salomon DR, Hayek A. Acid beta-galactosidase: a developmentally regulated marker of endocrine cell precursors in the human fetal pancreas. The Journal of Clinical Endocrinology and Metabolism. 78: 1232-40. PMID 8175983 DOI: 10.1210/Jcem.78.5.8175983  0.56
1994 Levine F, Beattie GM, Hayek A. Differential integrin expression facilitates isolation of human fetal pancreatic epithelial cells Cell Transplantation. 3: 307-313. PMID 7921635 DOI: 10.1177/096368979400300407  0.446
1994 Lu M, Maruyama M, Zhang N, Levine F, Friedmann T, Ho AD. High efficiency retroviral-mediated gene transduction into CD34+ cells purified from peripheral blood of breast cancer patients primed with chemotherapy and granulocyte-macrophage colony-stimulating factor. Human Gene Therapy. 5: 203-8. PMID 7514449 DOI: 10.1089/Hum.1994.5.2-203  0.341
1993 Hayek A, Beattie GM, Mally MI, Otonkoski T, O'Brien JS, Levine F. IDENTIFICATION OF A MARKER TO ENRICH POPULATIONS OF ENDOCRINE CELL PRECURSORS FROM THE HUMAN FETAL PANCREAS Pediatric Research. 33: S73-S73. DOI: 10.1203/00006450-199305001-00418  0.488
1992 Johnson PA, Miyanohara A, Levine F, Cahill T, Friedmann T. Cytotoxicity of a replication-defective mutant of herpes simplex virus type 1. Journal of Virology. 66: 2952-65. PMID 1373198 DOI: 10.1128/Jvi.66.5.2952-2965.1992  0.366
1991 Levine F, Jiing Kuan Yee, Friedmann T. Efficient gene expression in mammalian cells from a dicistronic transcriptional unit in an improved retroviral vector Gene. 108: 167-174. PMID 1660834 DOI: 10.1016/0378-1119(91)90431-A  0.33
1985 Levine F, Pious D. Different roles for cytosine methylation in HLA class ii gene expression Immunogenetics. 22: 427-440. PMID 2998981 DOI: 10.1007/Bf00418089  0.31
1985 Pious D, Dixon L, Levine F, Cotner T, Johnson R. HLA class II regulation and structure. Analysis with HLA-DR3 and HLA-DP point mutants. The Journal of Experimental Medicine. 162: 1193-207. PMID 2413154 DOI: 10.1084/Jem.162.4.1193  0.337
Show low-probability matches.